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<a href="https://shreygoel09.github.io/" target="_blank">Shrey Goel</a><sup>1</sup> <b>·</b> 
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<a href="https://www.linkedin.com/in/perin-schray-96855a32b/" target="_blank">Perin Schray</a><sup>2</sup> <b>·</b> 
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<a href="https://www.linkedin.com/in/yinuozhang98/" target="_blank">Yinuo Zhang</a><sup>
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<a href="https://www.linkedin.com/in/sophia-vincoff-185192146/" target="_blank">Sophia Vincoff</a><sup>
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<a href="https://www.linkedin.com/in/htkratochvil/" target="_blank">Huong T. Kratochvil</a><sup>2</sup> <b>·</b> 
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<a href="https://www.chatterjeelab.com/" target="_blank">Pranam Chatterjee</a><sup>
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<sup>1</sup> Duke University  
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<sup>2</sup> UNC—Chapel Hill  
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<sup>3</sup>
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<sup>4</sup>
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<sup>4</sup> Duke University
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# Token-Level Guided Discrete Diffusion for Membrane Protein Design
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arXiv preprint: https://arxiv.org/abs/2410.16735
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Reparameterized diffusion models (RDMs) have recently matched autoregressive methods in protein generation, motivating their use for challenging tasks such as designing membrane proteins, which possess interleaved soluble and transmembrane (TM) regions.
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<div align="center">
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<a href="https://shreygoel09.github.io/" target="_blank">Shrey Goel</a><sup>1</sup> <b>·</b> 
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<a href="https://www.linkedin.com/in/perin-schray-96855a32b/" target="_blank">Perin Schray</a><sup>2</sup> <b>·</b> 
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<a href="https://www.linkedin.com/in/yinuozhang98/" target="_blank">Yinuo Zhang</a><sup>3</sup> <b>·</b> 
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<a href="https://www.linkedin.com/in/sophia-vincoff-185192146/" target="_blank">Sophia Vincoff</a><sup>4</sup> <b>·</b> 
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<a href="https://www.linkedin.com/in/htkratochvil/" target="_blank">Huong T. Kratochvil</a><sup>2</sup> <b>·</b> 
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<a href="https://www.chatterjeelab.com/" target="_blank">Pranam Chatterjee</a><sup>4<sup>
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<br>
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<p style="font-size: 16px;">
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<sup>1</sup> Duke University  
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<sup>2</sup> UNC—Chapel Hill  
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<sup>3</sup> Duke-NUS Medical School  
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<sup>4</sup> University of Pennsylvania  
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Reparameterized diffusion models (RDMs) have recently matched autoregressive methods in protein generation, motivating their use for challenging tasks such as designing membrane proteins, which possess interleaved soluble and transmembrane (TM) regions.
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