"Me and You" debuted at number 68 on the Billboard Hot Country Singles & Tracks (now Hot Country Songs) charts dated for the week of July 20, 1996. The song spent twenty weeks on that chart, peaking at number 2 on the chart week of November 2, behind Clint Black's "Like the Rain". It also spend six weeks on the Bubbling Under Hot 100, peaking at number 12 on that chart (equivalent to number 112 on the Billboard Hot 100).
