Lowe started writing when she was in her single digits. She remains a prolific songwriter, penning hundreds of songs. She moved to Houston in 1977 to continue a career in music, playing regularly at clubs and listening rooms in Houston and Austin while often traveling back to Arkansas to perform. Her favorite club to perform was Rockefeller's where she opened up for major acts including Bonnie Raitt, Jessie Collin Young, Donovan, and Loudon Wainwright, III. She was a regular at Morgenstern's in College Station and Anderson Fair. In 1984, Lowe was recognised as a winner of Kerrville Folk Festival’s New Folk Competition. Her song "Let Her Go Gently" on the Little by Little album was published in Sing Out Magazine and her 1977 custom OM cutaway guitar was featured in an ad for Collings guitars in the November 2005 issue of the Acoustic Guitar Magazine.
