C. africana feeds on sponges. It is known to eat a species of the sponge genus Negombata.Rudman, W.B., 2005 (Oct 3). Comment on Chromodoris africana feeding by Lindsay Warren. [Message in] Sea Slug Forum. Australian Museum, Sydney.Rudman, W. B. & Bergquist, P. R. (2007) A review of feeding specificity in the sponge-feeding Chromodorididae (Nudibranchia: Mollusca). Molluscan Research, 27(2): 60-88
