Upon crossing into the city of Ise, Routes 42 and 167 meet the eastern terminus of the Ise Futami Toba Line, a limited-access highway signed as a bypass of National Route 42. The northern terminus and ending point of National Route 167 is at an intersection where the concurrency between it and National Route 42 meet National Route 23. National Route 42 continues beyond the ending point of National Route 167 in another concurrency with National Route 23.
