On February 3, 1927, the Guards were reorganized as Company E, 106th Engineers, part of the engineer unit of the 31st Infantry Division. The company became part of the regiment's Florida-based 2nd Battalion. During the interwar period, Company E held regular drills at their armory every Wednesday night and participated in a two-week annual summer training camp. In 1929 they were called up to enforce the Mediterranean fruit fly quarantine at Fort Meade with road patrolling duties and on July 14 were relieved by Company A of the 124th Infantry. When the National Guard was mobilized due to World War II, the company departed Apalachicola and left Panama City by train on December 17 with four officers and 69 men. On December 18, 1940, it arrived at Camp Blanding with other units from the battalion. It later served in WWII under the 31st Infantry Division. After WWII the company was reorganized as Cannon Company, 124th Infantry, then redesignated as Heavy Mortar Company, 124th Infantry on November 1, 1948.
