Wallace has two main branches of research, the first of these being on the development of techniques, applications and methods for circular dichroism spectroscopy and particularly synchrotron radiation circular dichroism (SRCD) spectroscopy. Her position as the major figure behind the advancement of SRCD, through performing "proof of principle" experiments and novel cutting edge studies on membrane proteins lead to her receiving the 2009 Interdisciplinary Prize from the Royal Society of Chemistry and the 2010 AstraZeneca Award from the Biochemical Society (UK).
