Following back to back wins over division rivals, the Colts' returned to Lucas Oil Stadium to face the Baltimore Ravens. Andrew Luck and the Colts' offense drove 59 yards on their first offensive possession, with the drive ending on a turnover after the Colts failed to convert a fourth down. On the first play of the Ravens' offensive possession, Steve Smith fumbled the ball, which was then recovered by Montori Hughes of the Colts. The Colts settled for a 38-yard field goal by Adam Vinatieri, giving then an early 3–0 lead. A muffed punt return by Jacoby Jones resulted in a second Ravens' turnover, however, on the ensuing Colts' drive, Haloti Ngata intercepted Luck, their first turnover of the game. After a stalled Ravens' drive early in the second quarter, the Colts drove 70 yards in 20 plays, though they again settled for a Vinatieri. The Ravens responded, scoring on a 52-yard field goal from Justin Tucker as time expired, cutting the Colts' lead to 6–3 at halftime.
