During his time at Washington University, Mohanakumar has made numerous contributions in his success of clinical and research programs, including the immunological mechanisms underlying transplant rejection. Along with heading transplant programs, he also supervises islet location and is the Director of Histocompatibility, an important component of bone marrow and organ transplantation. He has received accomplishments, awards, and citations from the American Society for Histocompatibility and Immunogenetics, American Society of Transplantation, and the Juvenile Diabetes Research Foundation. In his research, he has published more than 350 manuscripts and has served on many National Institutes of Health (NIH) study sections. Mohanakumar and his research group have been studying the processes of lung transplant rejection for more than 20 years. Recently, they found a possible diagnosis for chronic lung allograft dysfunction (CLAD) by monitoring proteins, such as Zinc finger and BYB domain-containing protein 7A (ZBTB7A).
