This catacomb was constructed in approximately 350 CE, and includes three main galleries which were carved out of the bedrock. The passageways of the catacomb diverge from a 25 meter stairway that leads down from the original entrance towards a well. The main burials are located approximately 7-9 meters below the surface level, and to the south-west of the stairway to the well. The gallery with the burials of Vibia, Vincentius, and Caricus is roughly at the center of the complex. The so-called arcosolium of the Vintners is north-west of these. Further down the passageway south of Vibia's burial, there is a burial for some priests of Mithras; branching off just before this, there is a separate square chamber which includes multiple burials in both arcosolia and slot graves. The chamber is supported by columns in each corner that were carved out of the tufa and form a cross-vault overhead.
