The A660 starts in Leeds city centre, officially at the junction of Woodhouse Lane and Claypit Lane. The northbound carriageway passes Leeds Metropolitan University's "civic quarter" campus, crosses the A58(M) (Leeds Inner Ring Road), which is in a cutting, and passes the University of Leeds with its landmark tower. The southbound carriageway is separated, at one stage by several terraced streets. The carriageways combine before crossing Woodhouse Moor to Hyde Park. The road passes the buildings of Leeds Girls' High School and climbs to Headingley, passing St Michael's Church and many shops and bars including the Arndale Centre. Shortly after the church, a plaque shows the site of the original oak tree which gave its name to the wapentake of Skyrack ("Shire oak"): this is reflected in two pub names and nearby Shire Oak Road. The road continues through Far Headingley and West Park.
