Higashi-Murayama Station is served by the Seibu Shinjuku Line, the Seibu Kokubunji Line, and the Seibuen Line. It is 26.0 km from the Tokyo terminus of the Seibu Shinjuku Line at Seibu Shinjuku Station and 7.8 kilometers from the terminus of the Seibu Kokubunji Line at Kokubunji Station. All trains (including limited express services) stop at this station. It is also the terminus station of the Seibuen Line.
