Tibiscus University started operating in 1991 as a limited liability company called the Institute of Studies and Continuing Education which organized university study programs, authorized to operate according to the legislative provisions of the time. In time, the institute changed its form of organization so that the study programs passed from the company, which was disbanded, to the association of the same name, ISEPT Tibiscus. In 1995, ISEPT Tibiscus founded, along with two other private structures, the Romanian Association for Unconventional Technologies and the Federation of Associated Farmers in Timiș County, a union called the Augusta Foundation.
