The 1942 Creighton Bluejays football team was an American football team that represented Creighton University as a member of the Missouri Valley Conference (MVC) during the 1942 college football season. In its second season under head coach Maurice H. Palrang, and its final season of intercollegiate football, Creighton compiled a 5–4 record (1–4 against MVC opponents) and outscored opponents by a total of 170 to 127. The team played its home games at Creighton Stadium in Omaha, Nebraska.
