The school was incorporated as a non-profit based out of Chicago, the location of its parent university, Midwestern University. AZCOM was the seventeenth osteopathic medical school to open in the United States. The first class of osteopathic medical students began classes on September 30, 1996. Upon graduating the first class of physicians on June 4, 2000, AZCOM received full accreditation by the American Osteopathic Association's Commission on Osteopathic College Accreditation.
