Fragile X syndrome (FXS) is a genetic disorder that is the most common single gene cause of intellectual disability and autism. Individuals with FXS often have a number of behavioral symptoms, including cognitive impairment, inattention, hyperactivity, impulsivity, autistic symptoms, shyness, aggression, anxiety, hand flapping, hand biting, and a high sensitivity to being touched. Autism spectrum disorder is seen in approximately 30% of males and 20% of females with FXS, and an additional 30% of FXS individuals display autistic symptoms without having the autism diagnosis. ADHD is commonly diagnosed in FXS and has been reported to occur in 59-80% of individuals with FXS.
