Although Tuke is already aware that insanity is also partially favored by a specific combination of genetic material and thus predetermined, in the last chapters he designates some characteristics and habits which can avoid insanity and terms this "auto-prophylaxes". He emphasizes that in general a mentally as well as physically balances life is of great importance to ensure mental health. This can reached by enough sleep, physical and mental exercise and a generally healthy lifestyle. He further stresses to distance oneself from any type of intoxication as it interferes with the regular cognitive functioning and also harms the cerebral cortex.
