After Skye and Jax exchanged vows, Jax's supposedly dead lover, Brenda, showed up to congratulate him. She wasn't dead after all, and had stayed away from Port Charles due to her mental illness. Jax later got shot while protecting Brenda and was temporarily paralyzed. Skye finally met Brenda in person when she found her sitting at Jax's bedside. Upset and jealous at first, Skye was somewhat relieved to learn Brenda was dying and didn't plan to try and win Jax back. Jax didn't feel it was right tying Skye to a crippled husband, so he enlisted Brenda's help in pushing her away. Hurt, Skye looked into Brenda's prognosis, and discovered that the doctor who had diagnosed Brenda's illness had been paid off by Luis Alcazar to falsely declare Brenda mentally ill. Skye kept the information to herself, but when Jax found out Brenda wasn't dying and Skye knew, he demanded a divorce, wanting to be with Brenda. Skye started drinking again. The night of Jax and Brenda's engagement party, Skye and Alcazar were both thrown out and ended up in bed together at his hotel suite. When Skye woke up, she heard Brenda arguing with Alcazar in the next room before passing out again. She awoke later to discover Alcazar had been pushed off the balcony to his death. Seeking revenge on Brenda, Skye told the police she saw Brenda kill Alcazar, but her constant state of drunkenness discredited her testimony. Skye later became the prime suspect, but eventually remembered seeing Alexis Davis push Alcazar.
