The TATA box is present in all genes that are transcribed by RNA polymerase II, which is most eukaryotic genes. The binding of the TATA box with TATA binding protein initiates the formation of a transcription factor complex. This is followed by binding of transcription factor TFIID, which then recruits TFIIB, TFIIF, RNA polymerase II and TFIIH (in that order) to form an initiation complex. It is typically 10 nucleotides long, and is present -30 to -20 nucleotides upstream from the transcription start site, in the core promoter region.
