Bruce developed an early interest in the use of computers in cardiology and established a computer laboratory in the Division of Cardiology. He devised a method for quantifying the QRS and ST segments in the EKG during exercise. In the late 1950s, he was also one of the first to suggest the possible benefit of thrombolysis in acute myocardial infarction. Bruce published more than 300 scientific articles, a major contribution to the knowledge of cardiovascular physiology in health and disease. He was a founding member of the Association of University Cardiologists and its second president, in 1969.
