Week 14 featured Eli Manning taking over for an injured Daniel Jones against the injury-ravaged Philadelphia Eagles. Following a scoreless first quarter, Manning delivered a 35-yard touchdown pass to Darius Slayton on the first play of the second to put New York up 7–0. After the teams traded field goals, Manning would throw another touchdown pass to Slayton, this time from 55 yards, to build the Giants' lead to 17–3 before halftime. However, the offense would fall silent in the second half, going three-and-out on four of six possessions and putting up just 30 yards of total offense. The Eagles would take advantage and score 14 unanswered points over the final two-quarters to force overtime. After the Eagles won the overtime coin toss, the Giants defense failed to slow Philadelphia down, and the Eagles prevailed on Carson Wentz's second touchdown pass of the night to Zach Ertz. With this loss, the Giants dropped to 2–11 on the year, and matched a franchise-worst nine-game losing streak set in 1976. Furthermore, the loss marked the first time that the Giants trailed the Eagles in their all-time series. It also marked the first time since 2006 a Eagles-Giants game went to overtime.
