A life member of the Actors Studio, McClanahan made her professional stage début at Pennsylvania's Erie Playhouse in 1957, in the play Inherit the Wind. She began acting off-Broadway in New York City in 1957, but did not make her Broadway début until 1969, when she portrayed Sally Weber in the original production of John Sebastian and Murray Schisgal's play with music, Jimmy Shine, with Dustin Hoffman in the title role.
