Samutsakhonburana School (abbreviated as S.K.N.) () is a provincial coeducational high school in Mahachai, Samut Sakhon, Thailand. The school was built as a school for women at Tha Chaloam, Samut Sakhon in 1912 by Khunsamutmaneerat (Mangha Maneerat). Samutsakhonburana School was subsequently rebuilt at Mahachai and transformed into a coeducational school.
