Leroy & Stitch, the finale to Lilo & Stitch: The Series, was released in 2006. Chase then appeared in the second season of Big Love, which aired in 2007. She also voiced Betsy in the PBS show Betsy's Kindergarten Adventures the same year. She reprised her role as Donnie Darko's younger sister, Samantha, in the film S. Darko. The story picks up seven years after the first film when Samantha Darko and her best friend Corey are now 18 years old and on a road trip to Los Angeles when they are afflicted by bizarre visions.
