The process of founding the country's public university began on 11 June 1833 with the passage of a law proposed by Senator Dámaso Antonio Larrañaga. It called for the creation of nine academic departments; the President of the Republic would pass a decree formally creating the departments once the majority of them were in operation. In 1836, the House of General Studies was formed, housing the departments of Latin, philosophy, mathematics, theology and jurisprudence. On 27 May 1838, Manuel Oribe passed a decree establishing the Greater University of the Republic. That decree had few practical effects, given the institutional instability of the Oriental Republic of the Uruguay at that time.
