Charles Locock was born to Henry Locock and his wife Susannah Smyth in Northampton. He studied under Benjamin Brodie and Andrew Duncan, graduating from medical school at Edinburgh University in 1821. Locock became a licensed doctor of the Royal College of Physicians in 1823 and a fellow in 1836. He opened his own obstetrical practice, which became the largest in London. In 1840 he became the first obstetrician to Queen Victoria, and was the attending doctor for the births of all her children. In 1842 he was elected a Fellow of the Royal College of Physicians. He published an 1857 paper in The Lancet outlining the use of potassium bromide as a treatment for epilepsy.Locock C. Discussion of paper by Sieveking EH. Analysis of fifty-two cases of epilepsy observed by the author. Lancet 1857; 1: 528
