There are no known predators of P. manokwari. However, it is a paratenic host for the nematode Angiostrongylus cantonensis, also known as the rat lungworm. This nematode parasitizes P. manokwari as well as the giant African land snail, and both of these organisms are transmission vectors of the parasite. A. cantonensis parasitizes humans as well and causes angiostrongyliasis. P. manokwari is presumed to act as a transmission vector of the parasite to humans and affects the epidemiology of angiostrongyliasis.
