Most parts of the Macrozamia miquelii are toxic with the seeds of the cycad having a higher concentration of azoxyglycosides, including cycasin and macrozamin, than other parts of the plant. Other toxins identified within the cycad include β-Methylamino-L-alanine (BMAA) which acts as a powerful neurotoxin if ingested. The ingestion of raw cycad seeds by an animal can lead to death and cause nausea and diarrhea in humans as well as death in some cases. Cycad leaves are also dangerous due to β-Methylamino-L-alanine and have been recorded to cause hind end paralysis and death in cattle.
