The majority of people require more than one medication to control their hypertension. In those with a systolic blood pressure greater than 160 mmHg or a diastolic blood pressure greater than 100 mmHg, the American Heart Association recommends starting both a thiazide and an ACEI, ARB, or CCB. An ACEI and CCB combination can be used as well. In general, medications should be implemented in a stepped care approach when people do not reach target blood pressure levels.
