Musaazi met Mary Ritah Nansikombi while he was at King's College Budo and she was at Gayaza High School. In 1936 they were married in Kenya. They were blessed with 11 children. Mary, who is now 94 years old, is the granddaughter of Sir Apolo Kaggwa who was a Katikkiro (Prime Minister) in the kingdom of Buganda Government, and is the daughter of Mary and Sepiriya Kaddumukasa. She recalls the difficulties which she and her family faced because of her husband's resolve to fight for Uganda's independence: "My husband was imprisoned 37 times.... he was charged with treason for organising Ugandans to rebel against the colonialists"."I never enjoyed my marriage – Nansikombi", New Vision Newspaper (Uganda), 9 June 2012.
