In June 2021, Missanelli launched his first off-air business entity, MikeMiss Ventures, that focuses on his interests outside of sports radio. Missanelli also launched "MikeMiss: The EveryDay Cook" show, based on his longtime passion for food and cooking and started "Behind the Mic", in which he evaluates aspiring broadcasters reels and provides feedback in a one-on-one call session and offers "MeetMike", a virtual meet and greet. In 2022, he released a children's book called "Shima the Shiba", which he details the human-like behavior of his Shiba Inu dog and how the dog can lay down valuable lessons in life for young children.
