On the US Billboard Hot 100, "Never Let You Go" first at appeared at number 65 on the week dated January 22, 2000, becoming that issue's "Hot Shot Debut". Ten weeks later, on April 1, 2000, the song reached its peak of number 14 on the Hot 100, and it stayed on the listing for 22 weeks, last charting at number 46 on June 17. The song became a top-five hit on four other Billboard charts, reaching number three on the Adult Top 40, number four on the Adult Alternative Songs and Modern Rock Tracks charts, and number five on the Mainstream Top 40. At the end of 2000, Billboard ranked the song as the 43rd-most-successful hit of the year. "Never Let You Go" became a number-one hit on Canada's RPM Top Singles chart, debuting at number 39 on January 24, 2000, and rising to the top position on the issue of March 27. In addition, the song peaked at number two on the RPM Top 30 Rock Report and number 37 on the Adult Contemporary Tracks ranking.
