Gréban may have come from the diocese of Cambrai; he lived in France and Italy. He was master of arts, bachelor of theology in 1458; from 1451 to 1456, he was organist and master of grammar and at the choir of Notre-Dame-de-Paris. He then served Charles, Count of Maine, until the death of the latter in 1472. He then left to Italy, was chaplain of San Lorenzo in Florence in 1476 and responsible for music at the House of Medici until 1485.
