Before competing in the college ranks, Jeffries attended high school at Bloomington High School North, advancing to the Indiana High School Athletic Association (IHSAA) basketball finals in 2000 before losing to Marion High School, led by fellow future NBA player Zach Randolph. In his last two years in high school, one of his teammates was future North Carolina player Sean May. Jeffries was recognized as the 2000 Indiana Mr. Basketball.
