Sheffield shared his toothpaste formula with his son, L. T. Sheffield, who was a dentistry student at Harvard during this period. In response to toothpaste demands from patients, Sheffield started a manufacturing company, in early 1880. Initially, Sheffield was making toothpaste batches at his dental office at the corner of State Street and Green Street in New London, Connecticut. Demand grew rapidly and he was forced to build a laboratory and manufacturing facility behind his residence.
