Mayambala was one of the ten candidates who challenged long serving president Yoweri Musaveni in the January 14, 2021 presidential polls. Mayambala was less vibrant in the presidential campaigns and came last with only 0.15 per cent or 15,657 votes he received. He blamed his paltry vote on the low turnout of voters (57.22%), and the Electoral Commission for not sensitising the electorates to vote during the election.
