Vaidišová captured her sixth WTA Tour title at the Tier III event in Strasbourg in May 2006. In June, she made a semifinal run at the French Open, her best Grand Slam performance to date. She defeated world No. 1 and home favourite, Amélie Mauresmo, in the fourth round and Venus Williams in the quarterfinal. However, she lost to Svetlana Kuznetsova in the next round, despite being only two points away from victory several times. At Wimbledon, she got to the fourth round before losing to Li Na. Vaidišová's fourth-round appearance meant that she has advanced to the round of 16 or better in each of the four Grand Slam tournaments.
