Research efforts during the 80-90s have shown that myocardial ischemia also induces changes to the depolarization phase and confirmed the use of HFQRS-RMS as a quantitative diagnostic measure of supply myocardial ischemiaMor-Avi V., Shargorodsky B., Abboud S., Laniado S., Akselrod S. Effects of coronary occlusion on high-frequency content of the epicardial electrogram and body surface electrocardiogram. Circulation 1987;76(1):237–43.Abboud S., Smith JM., Shargorodsky B., Laniado S., Sadeh D., Cohen RJ. High frequency electrocardiography of three orthogonal leads in dogs during a coronary artery occlusion. Pacing Clin Electrophysiol 1989;12(4 Pt 1):574–81.Abboud S., Cohen RJ., Sadeh D. A spectral analysis of the high frequency QRS potentials during acute myocardial ischemia in dogs. International Journal of Cardiology, 26: 285-290, 1990. and demand myocardial (stress-induced) ischemia.Beker A., Pinchas A., Erel J., Abboud S. Spectral Analysis of High Resolution QRS Complex During Exercise Induce Ischemia. Annals of Noninvasive Electrocardiology, 1(4): 386-392, 1996.
