After the death of Ferdinand II in 1516, ownership of the island was transferred to Cardenal Cisneros. The island changed ownership again in 1520, when Francisco de Barrionuevo became the island's new landlord. By 1524, Alonso Manso, bishop of Puerto Rico, had become interested in gaining personal wealth, and he accused Barrionuevo, among others, of various crimes under the Spanish justice system of the time. Because of this situation, Barrionuevo exiled himself to one of Spain's colonies in South America, taking many Taínos along with him, and leaving the island practically deserted.
