Atherosclerosis and hypertension are grave contributors in the group of pathological conditions under the umbrella of Cardiovascular disease. Among these conditions is also the disfunction of the endothelium, which given its properties of vasodilation when functional, can cause excessive vasoconstriction, thus leading back to hypertension. Another effect of this particular disfunction may also be excessive platelet adhesion, signifying a significant increase in blood clots, thus the promotion of a prothrombotic state.
