He split the 2019 season between the Single-A Quad Cities River Bandits and the Double-A Corpus Christi Hooks, posting a combined 6-3 record and 3.71 ERA with 93 strikeouts in 77.2 innings pitched. Bermúdez did not play in a game in 2020 due to the cancellation of the minor league season because of the COVID-19 pandemic. He spent the 2021 season split between Corpus Christi and the Triple-A Sugar Land Skeeters, logging a cumulative 5-6 record and 3.24 ERA with 146 strikeouts in 111.0 innings pitched.
