The reserve is home to many species of plants and animals, often endemic to the Andaman and Nicobars biogeographic region. Species of fauna in the reserve include: Nicobar scrubfowl (Megapodius nicobariensis, a megapode bird), the edible-nest swiftlet (Aerodramus fuciphagus), the Nicobar long-tailed macaque (Macaca fascicularis umbrosa), saltwater crocodile (Crocodylus porosus), Andaman water monitor (Varanus salvator andamanensis), giant leatherback sea turtle (Dermochelys coriacea), Malayan box turtle (Cuora amboinensis), Nicobar tree shrew (Tupaia nicobarica), reticulated python (Python reticulatus) and the giant robber crab (or coconut crab, Birgus latro).
