Thatcher, born Kristine Marie Schneider, began acting at 16 with a small professional company in her hometown, Lansing, Michigan. She went on to work at regional theaters across the country. Her first husband was actor Tim Thatcher, at which point she created the stage name of Margaret "Maggie" Thatcher. In 1985, while married to her second husband, actor Tom Blair, she met David Darlow while the two performed in Tom Stoppard's The Real Thing, at the Northlight Theatre in Chicago. Darlow became her third husband.
