Southwest Florida International Airport, located to the south of Fort Myers, is the area's primary airport for commercial traffic, serving 10.3 million passengers in 2021 and becoming one of the 50 busiest airports in the United States. Since 2022, the Lufthansa subsidiary Eurowings Discover operates a direct route between Fort Myers and Frankfurt Airport, the sole nonstop flight to Europe in the region; the airport also facilitates travel between 28 states as well as the Canadian provinces of Quebec and Ontario and Havana.
