Sisler returned to the Tigers for the 1960 season, and manager Dykes noted that he was not confident that his bullpen could help when needed, pointing to the previous season as a reference. The Tigers bullpen had won just nine games in 1959, but began 1960 with three straight victories, with Sisler pitching a scoreless two-inning appearance on April 22. His performance was considered a surprise, due to having a poor spring training. Although he pitched well in his first game of the season, he quickly lost his form, and by May 18, his ERA had risen to 5.06 and had a 1–2 record. It was at this point in the season that he began to turn his fortunes around and regained his effectiveness, and by August 12 he had lowered his ERA to 1.90. His season totals included a 2.47 ERA and a 7-5 win–loss record, both career bests, and added six saves in 80 innings pitched.
