The route turns northeast and heads back into Centre Township, becoming Keystone Way and passes through agricultural areas with some homes. The road heads into a mix of farmland, woodland, and residences as it winds northeast and enters Oliver Township. Here, PA 34 curves north across forested Limestone Ridge prior to heading northeast again and passing through farmland and woodland with some homes and businesses. The route runs through Buffalo Bridge and reaches an intersection with PA 849. Here, PA 849 turns north to join PA 34, heading through more rural areas before crossing into the borough of Newport. The two routes turn northwest onto South 4th Street, passing homes. PA 34 splits from PA 849 by turning northeast onto Market Street and passing through the commercial downtown. The route passes under Norfolk Southern's Pittsburgh Line prior to crossing the Juniata River into Howe Township. At this point, the road becomes Red Hill Road and runs through agricultural and wooded areas with some development. PA 34 comes to an interchange with the US 22/US 322 freeway, with a park and ride lot located northeast of the interchange, and continues through more farmland with some homes. The route turns north to cross forested Berry Mountain and curves east-northeast to run through forests in between Buffalo Mountain to the north and Berry Mountain to the south, heading into Buffalo Township and becoming Hunters Valley Road. Farther east, the road heads through a mix of farmland and woodland with some homes. PA 34 curves south and then east to reach its northern terminus at US 11/US 15 just west of the Millersburg Ferry across the Susquehanna River.
