In early 2018, Isaacson was hired by Paul Rosenberg for the EVP/GM position of Def Jam Recordings. Isaacson was the first major hire under new Def Jam CEO Paul Rosenberg, who started last November at the Universal Music subsidiary. Def Jam is home to the releases of various record labels, including Kanye West's GOOD Music,[1][2] and ARTium Recordings, headed by Def Jam's former executive vice president. Current artists include Alessia Cara, Logic, Big Sean, Kanye West, 2 Chainz, Jeezy, Jeremih, Pusha T, Vince Staples, Desiigner and Jhené Aiko among others. Isaacson separated from Def Jam in May, 2021 following the departure of Paul Rosenberg in February of 2020.
