The original leper colony was first established in Kalawao in the east, opposite to the village corner of the peninsula. It was there where Father Damien settled in 1873. Later it was moved to the location of the current village, which was originally a Native Hawaiian fishing village. The settlement was also attended by Mother Marianne Cope and physician Arthur Albert St. Mouritz, among others. In 1893–1894, the Board of Health tried to remove the last fishing village inhabitants in order to expand the colony to encompass the entire Kalaupapa peninsula, including Kalawao.
