Buff officially lost the American Flyweight Championship on September 14, 1922, in an eleventh-round technical knockout against the great Filipino boxer Pancho Villa at Ebbets Field in New York City. Buff was down twice in the tenth and once in the eleventh. From the fourth through the sixth, Villa showed a clear advantage and delivered considerably more blows. By the ninth, Buff was becoming groggy from the blows of his opponent. In the tenth Villa scored two knockdowns. In the eleventh, under a vicious attack, Buff slipped to the floor while up against the ropes and receiving a series of uppercuts."Pancho Villa Beats Buff and Wins Flyweight Title", Arkansas Democrat, Little Rock, Arkansas, pg. 17, September 15, 1922
