Author of over 300 articles in peer-reviewed journals, Jean-Pierre Boissel has, throughout his career, formulated and contributed to the implementation of innovative solutions to many a scientific and methodological hurdle healthcare players are customarily faced with. In the 1970s, he designed and directed the first randomized multicenter clinical trial with a control group in France in cardiology for the assessment of aspirin in secondary prevention.The EPSIM Research Group. Controlled comparison of aspirin and oral anticoagulants in prevention of death after myocardial infarction. NEJM 1982;307:701-8 During the same period, he sets up the first European lab mastering animal and human arterial smooth muscle cell line culture.Boissel JP, Bourdillon MC, Loire R, Crouzet B. Histological arguments for collagen and elastin synthesis by primary cultures of rat aortic media cells. Atherosclerosis 1976;25:107-10
