In February 2020, Whittome organised a letter signed by 170 MPs demanding that Jamaican-born offenders not be deported to Jamaica. During the COVID-19 pandemic, she worked as a part-time carer at a care home. Whittome appeared on Newsnight in April where she discussed shortages in PPE at her workplace. Shortly after her appearance on the show, she claimed that she had been dismissed from her job as a carer for "spreading misinformation". Her employer ExtraCare denied that there were any shortages in PPE at the care home, and also stated that Whittome had not been dismissed, but that her services were "no longer needed" as their own in-house care team could now meet their needs. In September ExtraCare issued a statement in which they admitted that there had been shortages of PPE at the care home, and that Whittome had helped to resolve this through public appeals in March and April.
