During April 2007, Grady tore his anterior cruciate ligament and was lost for the season. In August, Brown broke his hand. It appeared Minor was seriously injured on October 13 when he was carted off the field and left the stadium wearing a protective boot on crutches. However, he recovered and for the next two weeks he and Brown combined to replace the injured Hart. He had his second 100-yard game and first 150-yard game on October 27 of that season during the 34–10 Little Brown Jug game victory against the Minnesota Golden Gophers when he rushed for 157 yards on 21 carries, including a 46-yard run and one touchdown. Although Hart returned to play in the Paul Bunyan Trophy game against Michigan State on November 3, he left the game early and Minor started the second half. Hart missed the next game on November 10, but Brown and Minor had poor performances. In all three of Hart's full game absences, Brown was the starter. As a sophomore on the 2007 Michigan Wolverines football team, Minor improved his rushing totals to 385 yards on 90 carries, which was again second on the team to Hart.
