Settee began working with the Revd. William Cockran at the CMS missions at St. Peter’s (Dynevor) and Nettle (Netley) Creek. During the winter of 1841–42 Settee was sent to the Beaver (Weatherald) Creek–Moose Mountain region of Saskatchewan as a missionary to a band of Cree-Assiniboine of the Southern Plains Cree, However Settee, as a northern Swampy Cree, lacked kinship and language ties with the Southern Plains Cree and the mission ended in 1845.
