There were three players from the 1957 season to be drafted to the National Football League in the 1958 NFL Draft. It was the eighth time in team history that Houston players were taken in the draft. Tackle Hogan Wharton was taken by the San Francisco 49ers in the eleventh round (131st overall), but remained on the team through the duration of the 1958 season. Similarly, Don McDonald was taken by the Philadelphia Eagles in the twenty-ninth round (340th overall), but did not leave Houston until after the 1959 season. Tackle John Peters was taken by the Green Bay Packers in the thirtieth round (350th overall). While Donnie Caraway, another Houston player was drafted in 1958, he did not play with the Cougars for the 1957 season.
