Guilty Gear Isuka was the 176th-bestselling Japanese title in 2004, with 74,270 copies sold for PlayStation 2 as of December 26. It was "Best Fighting Game" at the Best of E3 2004 Awards from IGN, and was nominated for "Best Sequel Fighting" at the 2004 National Academy of Video Game Testers and Reviewers (NAVGTR) Awards, which went to Dead or Alive Ultimate. The game received mixed reviews from critics, with a score of 76% at GameRankings and 73/100 at Metacritic. Allgame's Damian Francis gave the game three-and-a-half stars out of five; Famitsus four reviewers scored it 7, 7, 6, and 7 (out of 10) respectively, with a total score of 27 out of 40.
