In Gadsden County, US 90 leaves the Central Time Zone and enters the Eastern Time Zone as it crosses the Victory Bridge over the Appalachicola River entering the City of Chattahoochee. Most of the road in the county is named "Memorial Blue Star Highway," except in specific cities. This area is where the route is closest to the Florida-Georgia State Line. It is also where the route gains a concurrency with County Road 269 between Bolivar Street (which is the westernmost street leading to Georgia) and Main Street. After passing by the Florida State Hospital, which includes the NRHP-listed U.S. Arsenal-Officers Quarters, another concurrency begins, this time with CR 269A, where the street name changes from West Washington Street to East Washington Street. After the route leaves the city and CR 269A turns north toward Georgia State Route 97, it starts to move further away from the border.
