Milkovich joined the NASA Jet Propulsion Laboratory after completed her PhD. There she has worked on the Mars Phoenix landing spacecraft, the Cassini–Huygens mission and Mars Reconnaissance Orbiter. Her first rover was Curiosity, for which she was responsible for high-resolution imaging using HiRISE. She was most proud of the Mars Science Laboratory parachute image of Curiosity's landing. HiRISE allowed Milkovich and scientists to take turns to choose where images were taken, and took suggestions from the public. She featured on C-SPAN representing NASA to talk about developments in Curiosity.
