Under the reign of Emir Ali ibn Muqallad (), the Banu Munqidh reached their territorial peak with the emirate extending from the Mediterranean port of Latakia to Apamea. The Seljuk conquest of Syria in 1085 and subsequent struggles with local Muslim lords reduced the Munqidh emirate to Shayzar and its environs. Under Emir Sultan ibn Ali (), the Banu Munqidh alternated between combating the Crusaders who landed in Syria in 1099 and paying tribute to them. During this period, the family also had to contend with Ismai'li newcomers encroaching on their domains. To firmly protect the emirate, Sultan ultimately put the Banu Munqidh under Zengid suzerainty. After the death of Emir Muhammad ibn Sultan () and his family in the 1157 earthquake, the emirate passed to the Zengid emir Nur al-Din, who granted it to the Banu al-Daya family.
