When compared with modern populations, USR1 shows closest genetic affinity to modern Native Americans, then Siberians and East Asians. USR1 does not cluster genetically with any modern Native American population. The genetic distance from USR1 to Mal'ta boy is the same as that from modern Native American populations to Mal'ta boy. USR1 shows additional genetic affinity for Denisovans that is not matched by modern Native Americans; this additional Denisovan affinity is likely due to sampling variation from an ancient population with higher levels of heterogenous Denisovan admixture.
