Andy Mayo was born Andrew C Guariglia on 1 August 1901 in Italy to Emil and Columbia Guariglia. In 1903 the family emigrated to Philadelphia, Pennsylvania, where they lived at 1330 Moore St in South Philadelphia, Pennsylvania. Mayo was the oldest of began his Vaudeville career in 1918 and took his stage name from his mother's maiden name, DiMaio. Andy became a naturalized citizen of the United States in 1918 and he toured on the Vaudeville stage circuit most of his life. He married and was divorced 1927, remarried to Florence Mayo on 7 January 1932 who performed with him throughout the remainder of his career. In 1938 while Florence was attending to the birth of their first child, Mayo discovered Virginia Mayo in St Louis to take Florence's place as the female horse trainer. In 1939 Florence. Andy and Virginia Mayo were featured in the musical short Gallons and Guys. In 1943 Virginia Mayo's movie career started to gather attention and Andy left the Pansy the Horse act to manage the blossoming actress's career and leaving Pansy to his brother Allen and Frances Englebrecht in the horse costume and Dorthy Carlson as the trainer.
