In his review for Allmusic, Greg Prato notes that "despite a lengthy absence from the concert trail, Primus is as wild 'n' wacky as ever, and not afraid to veer off into an extended jam on a moment's notice." He contends that "the Frizzle Fry portion certainly doesn't disappoint", elaborating that "while sonically the set is top-notch, the camera work could have been better... few front shots of drummer Alexander are included, so there is no clear view of what he's playing most of the time", but concludes that "these complaints are small; Hallucino-Genetics Live 2004 is a faithful representation of the group's reunion tour."
