In 2003, she and her brother Philip donated $2 million toward a new exhibition gallery at the Denver Museum of Nature and Science. In 2013 she endowed a $2 million chair in retinal diseases at the University of Colorado School of Medicine. In 2018, she made an additional gift to the Department of Ophthalmology and University of Colorado Hospital which led to the designation of the program as the UCHealth Sue Anschutz-Rodgers Eye Center.
