Towards the top of Superga, more riders would drop until only 12 riders remained up front. Wilco Kelderman () continued to set the pace in the group throughout the rest of the first lap, also taking maximum KOM points at the first passages of Superga and Colle della Maddalena. As the group climbed Superga for the second time, Jai Hindley () accelerated, taking with him Vincenzo Nibali (), Mikel Landa (), López, and Carapaz. Meanwhile, Almeida dragged Pello Bilbao (), Emanuel Buchmann (), Domenico Pozzovivo (), and Yates with him in the chase group, which slowly bridged up to the front group. The two groups merged with around left. Towards the top, the race leader, López, was unable to follow the pace. At around the same time, Carapaz attacked, building a lead of around 20 seconds towards the top of Superga. His lead hovered between 20 and 30 seconds until he reached the foot of Colle della Maddalena.
