On 6 August 2022, Walker-Peters made his appearance of the season in a 4–1 defeat to Tottenham Hotspur. A week later, Walker-Peters scored the equalising goal in a 2–2 draw with Leeds United. On 13 March 2023, Southampton said it was in touch with Hampshire Police after Walker-Peters received racist abuse on social media following the team's goalless draw with Manchester United on 12 March.
