Engram recorded his first career 100-yard game in a Week 1 35–17 loss to the Dallas Cowboys with 11 receptions, 116 yards, and a touchdown. In Week 3 against the Tampa Bay Buccaneers, Engram caught six passes for 113 yards and a 75-yard touchdown as the Giants won 32–31, catching the first career NFL touchdown from rookie Daniel Jones. On December 17, Engram was placed on injured reserve with a foot injury after missing the last five games. He finished the season with 44 catches for 467 yards and three touchdowns through eight games.
