right|thumb|US 13 southbound on the Salisbury Bypass past the MD 513 interchange in FruitlandUS 13 crosses the Passerdyke Creek into Wicomico County, where it continues northeast as South Fruitland Boulevard through a mix of woods and farms. Shortly after entering Wicomico County, the route diverges from US 13 Bus. at a semi-directional Y interchange. US 13 Bus. continues toward Fruitland and downtown Salisbury on South Fruitland Boulevard while US 13 turns northeast and upgrades into the Salisbury Bypass, a four-lane freeway that soon passes over the Delmarva Central Railroad's Delmarva Subdivision line.
