H. isora is a rich source of antioxidants, carbohydrates, proteins, fibre, calcium, phosphorus, and iron.Gayathri, P., Gayathri Devi, S., & Sivagami Srinivasan, S. S. (2010). Screening and Quantitation of Phytochemicals and Nutritional Components of the Fruit and Bark of Helicteres isora. Hygeia journal for drugs and medicines, 2(1), 57-62. Active phytoconstituents include gallic acid, caffeic acid, vanillin, and p-coumaric acid.Jain Amita, Sinha Prakriti; Desai Neetin S.; (2014) Estimation of flavonoid, Phenol content and antioxidant potential of Indian screw tree (Helicteres isora L.); International Journal of Pharmaceutical Sciences and Research (4):1320–1330.Raaman, N., & Balasubramanian, K.(2012) Antioxidant and anticancer activity of Helicteres isora dried fruit solvent extracts. Journal of Academic and Industrial Research (1), 148-152. Cucurbitacin b and isocucurbitacin b have been isolated from the roots.Bean, M. F., Antoun, M., Abramson, D., Chang, C. J., McLaughlin, J. L., & Cassady, J. M. (1985). Cucurbitacin B and isocucurbitacin B: cytotoxic components of Helicteres isora. Journal of Natural Products, 48(3), 500-500. Additionally, Satake et al. (1999) isolated rosmarinic acid and their derivatives; isoscutellarein and their derivatives; D-glucopyranosyl isorinic acid with rosmarinic acid; helisterculins A and B; and helisorin.
