Janković's next tournament was Family Circle Cup in Charleston where she lost in the semifinals to world No. 1, Caroline Wozniacki. She then played in the Fed Cup against Slovakia, beating Daniela Hantuchová and winning an epic doubles match with Aleksandra Krunić against Hantuchová and Magdaléna Rybáriková, saving three match points. With this, Serbia was placed in World Group I again. At Italian Open, Janković lost to world No. 1, Caroline Wozniacki in the quarterfinals for the third time in a row. Her ranking dropped to No. 10, the lowest it had been since the beginning of 2007. Janković was the tenth seed at the French Open. In the fourth round, Janković fell to fifth seed and defending champion Francesca Schiavone. As a result, she dropped out of top 10 for the first time since early 2007.
