The route was identical to that of the 2017 event. At 135.5 km, the race was approximately half the distance of the men's event. It started in Bastogne, from where it headed north past Liège to finish in the industrial suburb of Ans on the same location as the men's race. The route featured four categorized climbs: the Côte de la Vecquée, Côte de La Redoute, Côte de la Roche aux faucons and Côte de Saint-Nicolas. The top of the last climb of Saint-Nicolas comes at 5.5 km from the finish.
