First announced at the 2010 San Diego Comic-Con International by recurring cast member Patrick Warburton, the episode was written by series regular Tom Devanney and directed by series regular Brian Iles during the course of the ninth production season. Series veterans Peter Shin and James Purdum, both of whom having previously served as animation directors, served as supervising directors for the episode, with Andrew Goldberg, Alex Carter, Elaine Ko, Spencer Porter and Aaron Blitzstein serving as staff writers for the episode. Composer Ron Jones, who has worked on the series since its inception, returned to compose the music for "The Hand That Rocks the Wheelchair".
