In 1960, Facio and Alicia D'Amico opened a photography studio together. Facio co-founded La Azotea with María Cristina Orive in 1973. La Azotea was the first publishing house printing photo books in Latin America. In 1985, Facio established the Fotogalería of the Teatro Municipal General San Martín, which has become of the most prominent photographic exhibition spaces in Argentina. Facio served as the director of the gallery until 1998. In 1996, Facio illustrated Manuelita, a book of poetry by María Elena Walsh. A large exhibition of her work, taken between 1972 and 1974 and focusing on the effect that Juan Domingo Perón had on the country, was shown at the Museo de Arte Latinoamericano de Buenos Aires, MALBA, in 2018. She was granted the Platinum Konex Award from Argentina in 1992.
