Misra is known to have been involved in advanced researches in the fields of Diabetes and Obesity and is reported to have introduced novel definitions for obesity. His research interests included abdominal obesity and Syndrome X in Indians and is credited with development of dietary and exercise guidelines for Indians. His group has worked extensively on body fat depots, specifically hepatic and pancreatic fat, and their relationship with insulin resistance and the metabolic syndrome in Indian population. He has also conducted several intervention trials with nuts, edible oils and proteins in individuals having high risk for diabetes. He was a part of several research projects on the subject and his researches have been documented by way of over 300 articles published in peer reviewed journals. He is also associated with 15 scientific publications as a member of their editorial boards and has written editorials for The Lancet on three occasions. He is a member of the Scientific Advisory Board of Elsevier and is the Associate Editor of Journal of Diabetes, European Journal of Clinical Nutrition and Editor-in Chief of Diabetes and Metabolic Syndrome: Research and Reviews. Besides, he is a reviewer for over 30 journals including New England Journal of Medicine, Lancet, Circulation and The Journal of Clinical Endocrinology and Metabolism. In India, Dr Misra has been participant of top Advisory Committees relating to Diabetes and Cardiovascular diseases. He has been in advisory board member of National Program for Cancer, Diabetes, and CVD. He has been a member of World Health Organization Expert Group of Childhood Obesity and Indian Council of Medical Research Expert Groups for Childhood Obesity, Fatty Liver, Diabetes, and Gestational Diabetes. He has been a Member, Technical Advisory Group on Adolescent Health, Ministry of Health, Governing Committee National Institute of Nutrition, National Nutrition Monitoring Bureau, and Expert Committee for Drugs Controller General of India. He has also been member of National Drug Technology Committee, and National Task Force on Male Fertility
