The 2021 Úrvalsdeild kvenna is contested by 10 teams, eight of which played in the division the previous season and two promoted from the 2020 1. deild kvenna. The bottom two teams from the previous season, FH and KR were relegated to the 1. deild kvenna and were replaced by Keflavík and Tindastóll, the winner and runners-up of the 2020 1. deild kvenna respectively.
