Džeko also helped Roma reach UEFA Champions League quarter-finals by scoring the winning goal against Shakhtar Donetsk. Džeko was instrumental in Roma's qualification to UEFA Champions League semi-finals, their first in over 30 years. He scored in both quarter-final legs against Barcelona, which Roma won on away goals. In the semi-finals, Džeko scored in both legs, but it wasn't enough, as Roma were eventually eliminated by Liverpool 6–7 on aggregate.
