In late May 2019, Owusu was named in Ghana's 29-man provisional squad for the 2019 Africa Cup of Nations. He subsequently debuted for the Black Stars in early June, coming on as a substitute in a 1–0 friendly loss to Namibia. Despite his team's defeat, Owusu made a strong impression, and got included in James Kwesi Appiah's final 23-man AFCON selection. He was part of the Ghanaian team for the 2021 African Cup of Nations in Cameroon.
