The brigade fought on the Italian front in World War I. On 30 September 1926 the brigade command and 64th Infantry Regiment "Cagliari" were disbanded, while the 63rd Infantry Regiment "Cagliari" was assigned to the XXVI Infantry Brigade. On 5 April 1939 the 64th Infantry Regiment "Cagliari" was reactivated in Ivrea and the 59th Artillery Regiment "Cagliari" was raised in Casale Monferrato. On the same date the 59th Infantry Division "Cagliari" was activated in Vercelli and was assigned its two namesake infantry regiments and the 59th Artillery Regiment "Cagliari".
