Manesus (also spelled Manesos; ) was a Parthian prince, who served as military governor and official (strategos and bidaxsh) of Parthian-ruled Mesopotamia and Parapotamia, in addition to being the ruler of the Arabs (arabarch) who lived in those areas. He was also collector of customs (παρ[αλή](πτου); perhaps a derivation of Iranian păhrbed). He held these posts during the reign of King Vologases III (110–147).
