The 1999 McNeese State Cowboys football team was an American football team that represented McNeese State University as a member of the Southland Conference (Southland) during the 1999 NCAA Division I-AA football season. In their first year under head coach Kirby Bruchhaus, the team compiled an overall record of 6–5, with a mark of 5–2 in conference play, and finished third in the Southland.
