Since the start of the 21st century, a growing number of foreign and local investors have selected Isabela as site of their business ventures. Heading the list are Isabela's top investors, namely: Mindanao Grains Processing Company, Inc., SN Aboitiz Power- Magat Inc., Universal Leaf Philippines, Coca-Cola Bottlers Philippines, Inc., San Miguel Corporation, RC Cola and Pepsi Cola.
