Following the Olympics, Zverev reached his second Masters 1000 final of the year at the 2021 Western & Southern Open after defeating Lloyd Harris, Guido Pella, Casper Ruud and Stefanos Tsitsipas after a close three-set battle in the semifinal. Zverev had not won a match at the tournament in six prior appearances. He beat Andrey Rublev for the 17th title of his career and the fourth of the season, in 59 minutes, the shortest match in the tournament history.
