In October Act! became an occasional supporter of the government led by Matteo Renzi, whom Tosi held in high esteem, fueling rumors that the party might either enter in stable alliance with or join Renzi's Democratic Party (PD). However, during the party's national convention in February 2016, Tosi rejected any notion of a stable alliance with Renzi, while expressing his interest for an agreement with centre-right forces. In fact, Act! maintained its independence from the government, while occasionally supporting it and favouring the "yes" vote in the 2016 constitutional referendum, differently from the entire centre-right. The vote resulted in a huge defeat for Renzi, who resigned from Prime Minister and was replaced by Democrat Paolo Gentiloni, at the head of a similar centre-left government.
