Over the next several years, Americans and Natives launched raids against each other, usually targeting settlements. In 1780, hundreds of Kentucky settlers were killed or captured in a British-Native expedition into Kentucky. George Rogers Clark of Virginia responded in August 1780 by leading an expedition that destroyed two Shawnee towns along the Mad River, but did little damage to the Native war effort. As most of the Lenapes had by then become pro-British, American Colonel Daniel Brodhead led an expedition into the Ohio Country in April 1781 and destroyed the Lenape town of Coshocton. Clark then recruited men for an expedition against Detroit in the summer of 1781, but Natives decisively defeated one hundred of his men along the Ohio River, effectively ending his campaign. Survivors fled to the militant towns on the Sandusky River.
