In the epilogue, twenty years have passed since the team's victory over the Anti-Spirals. With many of Team Dai-Gurren having since finally retired, it is up to the new generations of pilots to prevent the Spiral Nemesis and ensure the safety of the universe. Other races across the galaxy, having contacted Earth upon being freed from the Anti-Spirals, have joined forces with President Rossiu of Kamina City and during the twenty years, created the Galactic Spiral Peace Conference. Yoko, now as Miss Yomako, has become the principal of the small school she worked as a teacher at during her seven years absence from the team. One of her students, Nakim, has become a representative of the galaxy in the Grapearl Squadron. Gimmy and Darry have used Simon's Core Drill to become the new pilots of Gurren Lagann. Viral has become the captain of the Super Galaxy Dai-Gurren and an emissary for Earth. Nia's memorial and her engagement ring are shown to have been placed next to the graves of Kamina and members of Team Dai-Gurren that sacrificed their lives in the final battle. Simon, still living as Simon the Digger, watches over them as a squadron of Gurren Laganns flies overhead through the night sky on their way to join their Spiral brethren in the stars.
