The species is geophilic, is abundant in soil and can be isolated around the world; it is in world wide distribution. However, it is rare in places such as the United States, United Kingdom, and Germany but common in South America. It is defined to be either cosmopolitan or confined to a certain graphical regions. The fungus can be found in soil of greenhouses and munition factories within these areas. The species itself commonly infects humans whom are closely tied to these areas because of agricultural work. In these areas, soil moisture is indicative role in the presence of the M. gypseum complex, areas with higher moisture tend to be preferred. Correlations between infections and soil types indicate that most improved soils of the clayey or clayey-sandy type are preferred, particularly those fertilized with keratinous manure. Additionally the fungus prefers soils with a pH of 7-7.5. Various soils in correlation with number of infections indicates that the fungus specifically prefers chernozemic soil (74%), of which positive isolates occur.
