The Red Sox defeated the Indians, 4–3, in the first game of a three-game series. Prior to the game, Kiké Hernández and Christian Arroyo were placed on the COVID-related injured list. Starter Eduardo Rodríguez notched his 10th win of the season after holding Cleveland to three runs on eight hits in seven innings. Adam Ottavino got the save. Jonathan Araúz, just called up from Triple-A, had a three-run homer, one of only three Boston hits. Boston also won the second game of the series, 5–3 in 10 innings. Starter Nathan Eovaldi went innings while allowing two runs on six hits. Kyle Schwarber had a first-inning home run, helping to stake the Red Sox to an early 2–0 lead. After Cleveland tied the game, 2–2, in the second inning, there was no more scoring until extra innings. J. D. Martinez put the Red Sox ahead on a three-run homer. The Indians got one run back off of Martín Pérez, who was relieved by Ottavino who earned his 10th save of the season. The win went to Garrett Whitlock, who pitched a scoreless inning as the sixth of eight total Boston pitchers. The Twins won the final game of the series, 7–5, despite Boston building a 4–0 lead after five innings. Starter Tanner Houck went innings and allowed three runs on one hit and four walks. Austin Davis, the fourth of five Boston pitchers, allowed three runs on three hits and took the loss. Rafael Devers had two home runs and Bobby Dalbec had one.
