On January 9, 2020, Dike was selected in the first round (5th overall) of the 2020 MLS SuperDraft by Orlando City having already signed a Generation Adidas contract. On July 25, 2020, he made his professional debut as an 75th-minute substitute for Tesho Akindele in a 1–0 victory over Montreal Impact during the MLS is Back Tournament round of 16. On August 22, Dike made his first start for the team in his first regular season MLS match and subsequently scored his first professional goal in a 3–2 defeat to Inter Miami. Four days later he scored his first career brace in a 3–1 win over Nashville SC. With three goals and two assists in five matches, Dike was named MLS Player of the Month for August 2020. In October, Dike was announced as #10 in the annual MLS 22 Under 22 list, the first Orlando player since Cyle Larin in 2017 to be included. With MLS electing to change the annual Rookie of the Year award to Young Player of the Year in 2020, Dike was the highest-ranked rookie but came third in the voting behind five-year pro Diego Rossi and second-year pro Brenden Aaronson.
