All C3 Picasso models have an anti-lock braking system (ABS), Electronic brakeforce distribution (EBD), child locks, remote central locking and two front airbags. Electronic Stability Control (ESC), once an option, is now included across the range. The vehicle is only available as a 5-seater, but with all models the three rear seats can be folded flat to increase the boot capacity from or including the hidden compartment to store the parcel shelf, up to a maximum of . The Exclusive model features a folding front passenger seat to increase the storage space further. All models in the range have a "Mistral Maxi Taylor" woven cloth interior; according to Citroën, top European engineers and designers including Donato Coco and Jean-Pierre Ploué were involved in designing the vehicle.
