On May 23, Ayton made his NBA playoff debut, scoring 21 points on 10-of-11 shooting, to go along with 16 rebounds, in a 99–90 victory in Game 1 of the First Round over the defending champion Los Angeles Lakers. In Game 2 of the Conference Finals, Ayton put up 24 points, alongside a buzzer-beating, game-winning alley-oop dunk, and 14 rebounds, in a 104–103 victory over the Los Angeles Clippers to take a 2–0 series lead. In Game 4 of the Conference Finals, Ayton put up 19 points, 22 rebounds and 4 blocks in a 84–80 victory over the Clippers. In Game 6 of the Conference Finals, Ayton put up 16 points and 17 rebounds in a 130–103 victory over the Clippers, to lead the Suns to the NBA Finals for the first time since 1993. In Game 1 of the NBA Finals against the Milwaukee Bucks, Ayton put up 22 points and 19 rebounds in a 118–105 win. The Suns went on to take a 2–0 series lead, but lost the series in 6 games.
