Titans defensive coordinator Dean Pees retired on January 20, 2020, after spending the last two seasons with the team. On the same day, it was announced that secondary coach Kerry Coombs would be leaving to rejoin the coaching staff at Ohio State. On January 28, 2020, the Titans hired Anthony Midget to replace Coombs as secondary coach. On February 6, 2020, former New Orleans Saints and St. Louis Rams head coach Jim Haslett was hired to be the inside linebackers coach for the Titans. Head coach Mike Vrabel decided not to hire a defensive coordinator for the season. Following the Titans' 20–13 defeat against the Baltimore Ravens in the Wild Card round of the playoffs, Vrabel revealed that outside linebackers coach Shane Bowen was defensive coordinator in all but title, and that Bowen made the defensive play calls.
