He returned to the Low Countries to serve in the household of the papal nuncio, Ottavio Mirto Frangipani, and went on to become canon, archdeacon, and dean of St Bavo's Cathedral, Ghent. After the death of Antoine de Hennin in December 1626, was appointed to the bishopric of Ypres. Around that period members of his English family resided at Shirburn in Oxfordshire. The estates having fallen to an heiress, Chamberlain, the next heir male, came to England, not so much to put up his claim as to resign it, in order to confirm the title of the heiress to Shirburn Castle. He was consecrated bishop of Ypres only on 5 November 1628.J. J. De Smet, "Chamberlain (Georges)", Biographie Nationale de Belgique, vol. 3 (Brussels, 1872), 409-410. On 16 June 1630 he assisted at the consecration of Servaas de Quinckere as bishop of Bruges.W. H. James Weale, Tableaux de l'ancienne école néerlandaise exposés à Bruges, exhibition catalogue (Bruges, 1867), p. 161.
