Central Lawrenceville has five land borders with the Pittsburgh neighborhoods of Upper Lawrenceville to the north, Stanton Heights to the east and northeast, Garfield to the southeast, Bloomfield to the south, and Lower Lawrenceville to the southwest. Across the Allegheny River to the northwest, Central Lawrenceville runs adjacent with Millvale (with a direct connector via 40th Street Bridge) and Shaler Township.
