In 1924, Dr. Fu Manchu, his army of dacoits and his vicious daughter Lin Tang are kidnapping the daughters of prominent scientists and taking them to his hidden base in the Atlas Mountains, where he demands that their fathers help him to build a device that transmits blast waves through a radio transmitter, which he intends to use to take over the world. He plans to keep (even wed) the girls in question. But Dr. Fu Manchu's archenemy, Nayland Smith of Scotland Yard, is determined not to let that happen.
