Keystone State primarily carried agricultural commodities north. In August 1855 she brought 3,300 sacks of wheat to Philadelphia. In November 1856 her cargo included 104 bales of cotton, and in December 1856, 50 casks of rice. In return, the ship carried a variety of manufactured or processed goods south. In March 1861 her cargo for Charleston included 950 barrels of whiskey, 350 hogsheads of bacon, 750 barrels of beer, 260 bales of cloth, 200 barrels of flour, 300 packages of boots and shoes, 100 cases of hats and caps, 70 carriages, and 250 boxes of candles.
