Depp was the daughter of John Burks Depp, a member of the Kentucky House of Representatives, and of Mariba Elizabeth Reneau (1846-1928). She was one of six children, including Elizabeth Eola "Lizzie" Depp Allen, Mary Pitsy Depp Rowland, Tipton Hanson Depp, Oren Richard Depp, and Lillie Belle Depp Matthews. Her middle names came from her maternal great grandmother, Mary Bayless Wood (1777-1863), and her paternal great grandmother, Mary Hanson Courts Depp (1793-1840).
