Dreifus began to work as a journalist in the mid-1960s. She had a regular column in the underground newspaper The East Village Other"Who Was Who". The East Village Other: The Rise of Underground Comix and the Alternative Press. Retrieved 7 December 2015. and contributed to other small presses. During the 1970s, she interviewed female figures including performing artists Goldie Hawn and Loretta Lynn and congresswomen Patsy Mink and Eleanor Holmes Norton. She also published reviews of feminist authors Germaine GreerDreifus, Claudia. "The Selling of a Feminist." Review of The Female Eunuch by Germaine Greer. The Nation. June 7, 1971. p. 728 and Florynce Kennedy.Dreifus, Claudia. "Female bodies and the law." Review of Abortion Rap by Diane Schulder and Florynce Kennedy. The Nation. October 11, 1971. p. 342.
