Despite doing poorly in the minor leagues in 1987, Madrid still earned a call up to the Major Leagues, and on July 20, 1987, he made his big league debut. In his first game, while facing the Seattle Mariners, he pitched 1 innings, allowing four hits and three earned runs. Still, the Brewers won the game 13–11. He would pitch two more games in 1987, going 0–0 with a 15.19 ERA in 5 innings overall. He allowed 11 hits, nine earned runs and one walk.
