As professor and head of the Department of Oral and Plastic Surgery from 1913-1944, Moorehead was senior author of the textbook Pathology of the Mouth and many research articles, and made advances in reconstructive surgery. In the summer of 1921, Moorehead, along with Henry Sage Dunning of New York and Truman W. Brophy, met in Chicago to organize the 1st association in North America of specialists in what would come to be known as plastic surgery. He also found time to serve on the staff of four other medical facilities, and maintain a private practice.
