Stoke beat Wigan Athletic 1–0 on 2 November, with a goal from Josh Tymon on his return from Injury. They then lost a third straight home match 2–1 against Birmingham. Three days later they ended that run with a 2–0 victory against Luton Town with early goals from Powell and an own goal from Tom Lockyer, The game also marked Harry Souttar's return from injury after a year out. Stoke put in a poor performance against West Brom, losing 2–0 before the season took a four week break due to the 2022 FIFA World Cup.
