Applying this technology to the organ transplantation, his team extracted pancreatic islets from wild type pigs, and transplanted those into hepatic portal vein in non-human primates. His team treated the monkeys with the anti-ICAM1 epitope antibody before the xenotransplantation process, expecting the induction of immune-tolerance to the pancreatic antigens of other species in the non-human primates. This trial of xenotransplantation of pancreatic islets was proved to be a fantastic success, inhibiting graft rejection for almost a year. Park's work has been continued to the further researches on the possibilities of various clinical applications. To offer an extended therapeutic scope using the induction mechanism of immune tolerance, his team is investigating the possibilities of transplantation of various organs and treatment of autoimmune disease.
