The p75 receptor and co-receptors have been found to influence the aggressiveness of tumors, specifically via the ability of neurotrophins to rescue cells from certain forms of cell death.Bassili, M., Birman, E., Schor, N. F., Saragovi, H. U. (2010). Differential roles of Trk and p75 neurotrophin receptors in tumorigenesis and chemoresistance ex vivo and in vivo. Cancer Chemotherapy and Pharmacology, 65, 1047-1056.
