From 1735, he was engaged in preparing Guarini's Architettura Civile for publication in 1737. Following the death of Juvarra in 1736, several architectural commissions came his way. However, when the royal House of Savoy resumed its patronage of architecture in the early 1740s, they appointed Benedetto Innocente Alfieri as their architect, not Vittone. Instead, Vittone built up a clientele of patrons for who he designed buildings in the area around Turin.
