The Agence Nationale de Sécurité du Médicament et des Produits de Santé (ANSM) reported that the compound has a rat IC50 of 1.1-1.7 micromolar, and that this is 200 times the concentration required for inhibition with a different FAAH inhibitor developed by Pfizer (that is, much weaker). As such, the ANSM described the molecule as "a compound with a relatively poor specificity for the endocannabinoid FAAH." In the same report, the ANSM also noted that the inhibitor is irreversible, not reversible as claimed by the manufacturer Bial.
