The William Winston House is a historic residence in Tuscumbia, Alabama. Construction was begun in the early 1800s by merchant Clark T. Barton and finished in 1824 by planter William Winston. Winston's son, John A. Winston, was Governor of Alabama from 1854 until 1857; Winston's daughter married another Governor, Robert B. Lindsay. The house remained in the family until 1948, when it was sold to the city, which constructed a new campus for Deshler High School around the house.
