East of Bryan the road heads east, passing through mostly farmland with a few houses and some woodlands. The road becomes very curvy, before turning southeast. In eastern Williams County the highway crosses over the Tiffin River and has an intersection with SR 191. This intersection is the eastern end of the SR 2 concurrency with SR 2 heading north concurrent with SR 191. The road continues southeast, passing through farmland and entering Henry County. In western Henry County the route has a traffic signal at SR 66. The eastern terminus is at an intersection with US 6, northwest of Ridgeville Corners.
