Of the bishops who occupied the See of Assisi during the fifth and sixth centuries, Aventius interceded (545) with Totila in behalf of the Assisians, and saved the city from the Ostrogothic army on its way to Rome. In succeeding centuries mention is made of several Bishops of Assisi who were present at general councils of the Church. Thus, in 659, Aquilinus was summoned by Pope Martin I to be present at the Lateran Council, convened for the purpose of formulating decrees against the Monothelites.
