White made his professional regular season debut and first career start on September 9, 2018 in the Los Angeles Chargers’ season-opener against the Kansas City Chiefs and recorded six combined tackles in their 38–28 loss. On September 16, 2018, White recorded four solo tackles, broke up two passes, and made his first career interception during a 31–20 win at the Buffalo Bills in Week 2. He made his first career interception off a pass thrown by Bills’ rookie quarterback Josh Allen intended for tight end Jason Croom, and returned it for a nine-yard gain in the game's fourth quarter. In a Week 3 game at the Los Angeles Rams, White suffered a knee injury that required minor surgery, and he was inactive for the following four games (Weeks 4–8). On November 3, 2018, the Chargers announced he was being placed on injured reserve.
