Insulin resistance in women with PCOS is typically treated with insulin-sensitizer drugs such as metformin. Metformin can help to decrease weight and androgen levels. When combined with lifestyle modifications (changes in diet and exercise), it has been linked with lower body mass index and a reduction in menstrual problems. However, the use of metformin in women with PCOS should only be considered in patients with impaired glucose tolerance.Edited by Adam Balen Stephen Franks Roy Homburg and Sean Kehoe
