His eldest son Henry Bourchier Fane was killed in a duel by Elizeus Burges, who later was British Resident in Venice. The second son, his heir, Charles was created Viscount Fane (1675/76–1744). The third son George (d. 1709) was a Captain in the Royal Navy and died a commander of (launched 1697) in the harbour of New York. Another son Henry (c. 1685–1712/13) was one of the nominees for the first British tontine of 1693. There was a fifth son, Thomas.
