The protagonist of the series is a shy young girl named Shizuka and her outgoing male friend Mamoru. The series revolves around Shizuka's high school life after she contracts "Translucent Syndrome", a mysterious condition which has only one symptom: The victim's body randomly turns translucent (and later completely invisible), but is otherwise left perfectly normal and healthy. Unfortunately for Shizuka, there is no known cure or treatment for Translucent Syndrome, other than it is tied to the emotional state of the person affected; positive emotions like happiness and love cause it to retract, negative emotions like stress and sadness cause it to accelerate.
