At the start, Álex Palou took the early lead of the race, with Rinus VeeKay and Scott Dixon behind. Dixon eventually passed VeeKay for second, allowing him and his teammate Palou to exchange positions regularly to drive to conserve fuel. These three remained at the front through to the first pit stops, which came around lap 31. After pit stops, VeeKay emerged ahead of Dixon for second. On lap 39, VeeKay caused the race's first caution period after losing control of his car in turn two and impacting the outside wall. VeeKay was uninjured, but was relegated to finishing 33rd and last. After the accident, Chip Ganassi Racing cars ran 1–2–3, with Palou leading Dixon and Marcus Ericsson.
