In 1842 Wentworth married Anne McNeil, a daughter of Solomon McNeil and niece of John McNeil Jr. John McNeil was married to Elizabeth Pierce, the daughter of Benjamin Pierce, and the sister of Benjamin Kendrick Pierce and Franklin Pierce. Because of the family connection to Franklin Pierce, who was president during Wentworth's House term, Wentworth was able to maintain cordial relations with Democrats despite disagreeing with them politically. As a result, he was sometimes employed by Whigs as a negotiator to create compromises with congressional Democrats and the Pierce administration.
