The only highway in Hannan District is West Virginia Route 2, which runs along the Ohio River between Huntington and Point Pleasant. Other important roads include Jerry's Run Road, or County Road 37, which runs eastward from Route 2 at Mercers Bottom to U.S. Route 35 at Pliny, in Putnam County; and Ashton-Upland Road, County Road 41, which runs southeast from Route 2 at Ashton to Upland in the interior part of the district. From there, the road continues south to Mount Olive, and then to Milton in Cabell County, where it becomes John Morris Road; Mount Zion Road runs eastward from Upland to Fraziers Bottom in Putnam County, while Five and Twenty Mile Creek Road runs northeast from Mount Olive, also finishing at Fraziers Bottom.
