In 1963, Pierikos played for the first time in the First National Division where he stayed for 9 whole years, while in the same year reached the final of the Greek Cup facing Olympiakos. Club's performances were often impressive, as it consistently finished in the top 10 of scoreboard of the league. In 1972 was demoted but returned soon. In 1975 the team got promoted to the First Division again and remained for 3 years. The club was then demoted again. Pierikos was promoted three more times to the First National, but never managed to establish itself again in the 1st Division. The biggest distinction of the club was to finish 3 times in the 5th place of the championship, but also the Cup final against Olympiakos in 1963 where it was defeated 3–0.
