Comello was born and raised in San Daniele del Friuli near Udine in Friuli. She demonstrated her passion for art, acting, dance, guitar from a very young age. She started guitar lessons at age 8. In high school, she studied music theory and participated in dance and acting in her spare time. She attended I.S.I.S. Superiore Vincenzo Manzini, a public high school in San Daniele del Friuli. During her time at school, she won a science writing contest and was awarded a trip to Austria. She graduated high school in 2008. After completing her high school studies, she auditioned for and later took courses in music at M.A.S.: Music Arts & Show, a drama school in Milan, Italy in 2009. She attended M.A.S. from 2009 to 2011. In 2009, she was cast as a performer for the "Il Mondo di Patty" tour, the Italian version of the widely successful Argentine children's program, Patito Feo. The tour held concerts in Italy and Spain. She also appeared as a backup vocalist for Brenda Asnicar's special section of the same tour in Italy.
