Like all Kryptonians, Ursa is vulnerable to Kryptonite and red solar radiation. Her virtual invulnerability does not provide protection from mind control or magic and can be overpowered and cause her to experience significant and even fatal injuries with significant force such as that of several atomic explosions or strikes from an opponent with superior strength and durability such as Doomsday. Her superhuman strength is inferior to the likes of Doomsday and her superhuman speed is inferior to Speedsters like the Flash. Her superhuman strength is limited due to her natural limits even while within the empowering light of Sol.
