After Echenique arrived at Wichita State, he collapsed after a workout, prompting him so see a cardiologist to see if he had a heart condition. The examination proved that his heart was healthy, Echenique just needed to work through his conditioning. As a junior, he averaged 9.2 points, 6.0 rebounds, and 1.4 blocks per game. Echenique considered redshirting his senior season, an idea coach Gregg Marshall rejected. He missed several games in the beginning of the season with a fractured hand. He posted season-highs of 20 points and 13 rebounds on January 15, 2020, in a 65–53 loss to Temple. On February 20, Echenique tied a career-high of 20 points and had a career-best 12-of-14 shooting from the foul line, along with nine rebounds, four blocks and two steals in a 65–55 victory over South Florida. As a senior, Echenique averaged 11.3 points, 7.1 rebounds and 1.6 blocks per game. He earned Second Team All-AAC honors.
