In 2002, a fatwa was issued by the Supreme Leader of Iran regarding the permissibility of “destruction of residual embryos from the in vitro fertilization cycle for the purpose of obtaining stem cells for research purposes” as accreditation for the country's ESCs scientific community. Following this positive fatwa, the stem cell department of the Royan Institute in Tehran was established in the same year to establish the ESCs lines and to develop techniques to differentiate these lineages into various mature cell types including cardiomyocytes, B cells, and neurons.
