Nikolaus Federmann (, ) (c. 1505, Ulm – February 1542, Valladolid) was a German adventurer and conquistador in what is modern-day Venezuela and Colombia. He is a significant figure in the history of Klein-Venedig (1528–1546), the concession of Venezuela Province that Charles I of Spain granted to the Welser banking family and the foundation of Santafe de Bogotá.
