The institute is roughly divided into two parts: Collection Management and Research. Researchers carry out investigations in taxonomy (biology) and evolutionary biology of fungi, ecological and genomic issues are often involved. The institute also acts as a centre of expertise for questions related to fungi, yeasts and bacteria from scientists, business, government and the public. The institute also organises courses in general mycology, medical mycology, mycology relating to food and to the built environment. The CBS collection has been recognised as a repository of proprietary molds, yeasts and bacteria. The Institute carries out identifications of microorganisms for third parties and advises on problems caused by fungi and yeasts.
