the effect of dementia. Parkinsonism Rel Disord 1998;4:179–181. While there are effective treatments for the motor symptoms of PD, unfortunately, there are few treatment options for cognitive impairment, in large part due to a limited understanding of its causes in patients with PD. The Center will address this limitation through studies involving patient volunteers and through the development of models to better understand what brain changes lead to cognitive impairment in PD. Better understanding could lead to new treatments for this significant problem for patients with PD. In addition to generating new discoveries, the Pacific Udall Center will develop novel resources for other clinical, translational, and basic science researchers studying cognitive impairment in PD.
