Mangini and Pop Rox's remix of the Marvin Gaye song "What's Going On" was included in the charity album of remixes released by Columbia Records in 2001. Also in 2001, Mangini produced O-Town's first full-length album O-Town and David Byrne's sixth solo album Look into the Eyeball. During this phase of his career, Mangini worked with musicians such as the Jonas Brothers, and Bruce Hornsby.
