Incumbent Democratic Congressman Eli T. Stackhouse of the 6th congressional district, in office since 1891, died on June 14, 1892, during the Democratic primary campaign. A special election for the remainder of the term was called to be held simultaneously with the regular election. The South Carolina Democratic Party decided that the winner of the primary election would be their candidate for both the special and regular elections. John L. McLaurin won the primary and defeated Republican challenger E.J. Sawyer in the general election.
