Dane was a strong advocate of self sufficiency for the manufacture of blood products in Britain from freely donated blood, rather than from imported blood from the US where donors were paid. The consequences of not following this advice, and Britain’s failure to be self-sufficient for treatment of haemophiliacs made the UK reliant upon importation of the then "new" treatment of factor VIII concentrate. Potentially disastrous for groups such as haemophiliacs, who early on became infected with HIV, his advice to James Wallace "Jimmie" Stewart to reserve concentrate use to those whose management absolutely depended on it saved many from HIV infection. He also was early to recognise the occurrence of hepatitis other than hepatitis A and B following treatment with the anti-haemophiliac concentrate.
