Sadho was General secretary of Indian Youth Congress, Madhya Pradesh from 1985 to 1992. She served as a member of Madhya Pradesh Legislative Assembly from 1985 to 1989. She has been a member of Public Accounts Committee, Committee on Women and Child Welfare and Committee on the Welfare for SC, ST and Other Backward Classes. From 1989 to 1990, she served as a parliamentary secretary. She was a member of Department of Public Health and Family Welfare and Department of Jails, Govt. of Madhya Pradesh from 1993 to 1998. From 1985 to 2018 she got elected to the MP Legislative assembly for 5 terms. She lost the elections in 1990 and 2003. In 2013 she didn't contest the elections as se got elected to Rajya Sabha.
