The Freeport Main Street Historic District encompasses a 1-2 block area of Main Street (U.S. Route 1) in Freeport, Maine. It extends from Grove and Holbrook Streets in the south to Mill and Nathan Nye Streets in the north, just south of the L. L. Bean complex. The district, listed on the National Register of Historic Places in 1977, encompasses a well-preserved remnant of Freeport's 19th century town center.
