On August 4, 2017, Márquez announced his retirement from professional boxing after a 21-year career. Márquez spoke to ESPN Deportes TV show Golpe a Golpe, "Today is a special and sad day for me because I'm announcing my retirement. The injuries pushed me to make this decision. It hurts, but I believe the right moment to put an end to my career has arrived. I would have loved to do a final fight to say goodbye inside the ring, but I have to listen to my body, and it was telling me that the right moment to stop boxing is now." He ended his career with a record of 56 wins, 7 losses and 1 draw, with 40 knockouts. Márquez admitted the decision was hard to make, but initially made the decision 10 days prior to announcing it.
