The 2016–17 Penn Quakers women's basketball team represented the University of Pennsylvania during the 2016–17 NCAA Division I women's basketball season. The Quakers, led by eighth year head coach Mike McLaughlin, play their home games at the Palestra and are members of the Ivy League. The team was picked by the Ivy League in the pre-season to be conference champions. They finished the season 22–8, 13–1 to win the Ivy League regular season title and their first ever Ivy League Tournament to earn an automatic trip to the NCAA women's tournament, which they had a 21 point lead before losing to Texas A&M in the first round.
