Attalus II also made frequent diplomatic visits to Rome, and sent frequent envoys such as Andronicus of Pergamum, gaining the esteem of the Romans. At one point, they offered him assistance to overthrow his brother, but he declined. When his brother died in 159 BC, his nephew was too young to rule at the time, so he ascended the throne as regent and married Stratonice once again. The Romans had assisted him in his own battles against Prusias II in 156–154 BC. In the summer of 152, he, Ptolemy IV, Ariarathes V, and Rome, helped the pretender Alexander Balas to seize the Seleucid throne from Demetrius I and in 149 BC, he helped Nicomedes II Epiphanes to seize the Bithynian throne from his father Prusias II.
