Radiation therapy has been seen to also have a direct impact on the uterus, leading to changes to its vascular supply, volume and elasticity. Necrosis, atrophy and fibrosis have also all been observed in the endometrium and myometrium. Changes such as these have significant consequences in regard to pregnancy outcomes; studies suggest cancer patients receiving radiation have a higher chance of experiencing miscarriages or having low birth weight, premature children. The likelihood of perinatal infant mortality and low birth weight are significantly related to radiation dose.
