Lanihau married a man named Opeka. His name is sometimes given as J. Opeka or Benjamin Opeka. They had a number of children although they are not all known by names. Two known daughters: Hannah Kailinaoa Opeka (1876–1914) and Mary Kiliwehi Opeka (1877–1909) attended the Kawaiahaʻo Seminary for Girls (precursor of the Mid-Pacific Institute).
