Unlike other crossover events published by DC, the conflict of The Final Night did not revolve around a conventional villain. It was primarily a story of survival that focused on the main characters performing disaster response, while attempting to prevent impending mass extinction of all life on Earth. At the end of each issue was an in-story website feature written by S.T.A.R. Labs, giving information updates and emergency support to residents of the DC Universe as the crisis progressed.
