The most notable endangered species of fauna in the park are Diana monkey, giant bongo antelope, yellow-backed duiker and African elephant. It is also an Important Bird Area recognized by the Bird Life International with the bird area fully overlapping the park area. The bird inventory confirmed 266 species in the park, including eight species of global conservation concern. One of these species of concern is the white-breasted guineafowl. Nine species of hornbill and the grey parrot have been recorded. It is very rich in butterflies as well, and a new species was discovered in 1993. As of 2012, the densest population of forest elephants in Ghana is located in Kakum.
