PTH 16A continues along Main Street before meeting westbound PR 355 (6th Avenue N.W.) at the north end of the town. The highway leaves Minnedosa after passing PR 355 and starts transitioning to an east-west route for as it climbs out of the valley, completing the transition once it reaches the top. From this point, PTH 16A continues for to its western terminus with PTH 16 and PTH 10.
