Wolpoff was trained primarily as a paleoanthropologist at the University of Illinois under Eugene Giles. With his multidisciplinary training, he brings to the study of the human and non-human primate fossil record a background that combines evolutionary theory, population genetics, and biomechanics. With over 50 grants funded by the National Science Foundation, National Academy of Sciences, and the University of Michigan, Wolpoff has visited the museums where human and primate fossils are stored and has studied in detail and at length all the materials addressing the fossil evidence for human evolution across Europe, Asia, and Africa. His research foci have included the evolution and fate of the European Neandertals, the role of culture in early hominid evolution, the nature and explanation of allometry, robust australopithecine evolution, the distribution and explanation of sexual dimorphism, hominid origins, the pattern and explanation of Australasian hominid evolution, the contributions and role of genetics in paleoanthropological research, and the taxonomy of the genus Homo. In addition, he is a primary describer of many hominid fossil remains. Since 1976 Wolpoff has graduated more than 20 PhD students.
