Residues in the transmembrane domain of KCNE1 lies close to the selectivity filter of KCNQ1 within heteromeric KCNQ1-KCNE1 channel complexes. , The C-terminal domain of KCNE1 , specifically from amino acids 73 to 79 is necessary for stimulation of slow delayed potassium rectifier current by SGK1 .
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