The caspase-3 His-237 stabilizes the target Aspartate causing the break of the association of ICAD and CAD leaving the endonuclease CAD active allowing it to degrade chromosomal DNA .
DET PROPN NOUN VERB DET NOUN PROPN VERB DET NOUN ADP DET NOUN ADP PROPN CCONJ PROPN VERB DET NOUN PROPN ADJ VERB PRON PART VERB ADJ NOUN .