After her studies, Giorio became a postdoc at the University of Padova where she worked on the environmental dispersion of neonicotinoid insecticides through dust emitted by seeders during the sowing of corn seeds treated with neonicotinoids, and the consequential in-flight contamination and acute toxicity for honeybees. She also worked on assessing the usability and environmental impact of vineyard pruning residues as an energy source.
In 2013, Giorio transferred to the University of Cambridge as a postdoctoral research associate in the Department of Chemistry in the Markus Kalberer research group. In Cambridge, Giorio‘s research was focused on determining the chemical composition and formation processes of secondary organic aerosols. She developed a method for the quantification of the highly reactive Criegee intermediates produced by ozonolysis reactions in the atmosphere and she studied the impact of aqueous phase processing on aerosol composition 
In January 2017, Dr. Giorio became a researcher at the French National Centre for Scientific Research and later that year, became tenure-track Assistant Professor at the University of Padova. As of March 2020, she is an Assistant Professor at the University of Cambridge. Research in Giorio’s Research Group is focused on the chemistry of the Earth’s atmosphere and its impact on air quality and climate.