Kobozev actively studied thermodynamics and etropy. He believed that neither cells or molecules, nor atoms could factor reasoning. In order to explain it, he introduced the concept of special particles called psychons. In 1948 he also introduced the concept of vector-brownian motion aimed at finding out what in the nerve system rules living being's behavior. His work on the vector-brownian motion is believed to be the predecessor of cybernetics.
Kobozev had a specific concept of time in regards to life and death relationship. He classified time into translational (time of collective development) and dispersional (time of personal development). He believed that humans reasoning is tightly connected to the current time, while death is a persons disconnection from the knot (klubok) of the current time. In 1954 he developed the concept of advanced complex (operezhayuschiy kompleks) in chemical kinetics and worked on the problem of time in quantum mechanics.
Regarding reasoning, Kobozev believed it cannot be evolved from information, and it is given to a human with birth. He also believed that every ethnicity (race) has had its own symbolic means of communication expressed in language from creation rather than developed it during evolution.
He introduced the terms of negative entropy, which he thought was essential part of logic, and anti-entropy, which blocked systemic thinking.