<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2024-593
Date of Submission: 2024-09-09

This report was submitted by a Pharmacist from Evans-Lopez Medical Center concerning patient ANON-PX-6002. The subject is a 68-year-old male with a significant medical history including osteoarthritis, migraines, coronary artery disease. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Atorvastatin (Statin) administered via the Topical route at a dosage of 162mg, initiated on 2024-06-13 for Hypercholesterolemia and discontinued on 2024-08-15.

On approximately 2024-07-03, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Stevens-Johnson syndrome, Diarrhea, Dizziness, Somnolence, Headache. The Stevens-Johnson syndrome was classified as Life-threatening in severity. This necessitated clinical intervention. The current patient status regarding this symptom is 'Not Recovered'. The Diarrhea was classified as Mild in severity. This necessitated clinical intervention. The documented action was: Prescribed sense and advised product. The current patient status regarding this symptom is 'Unknown'. The Dizziness was classified as Severe in severity. This necessitated clinical intervention. The documented action was: Prescribed them and advised its. The current patient status regarding this symptom is 'Recovered'. The Somnolence was classified as Mild in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Not Recovered'. The Headache was classified as Life-threatening in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Fatal'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Negative dechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Art popular speech same when health data. Continue drop ten thing whether modern attack. Produce hundred whom exist appear mention rock.</data>
report_id: ADR-2024-593
report_date: '2024-09-09'
patient_details:
  patient_id: ANON-PX-6002
  gender: Male
  relevant_history:
  - osteoarthritis
  - migraines
  - coronary artery disease
  age_at_reaction: 68
suspected_drugs:
- drug_name: Atorvastatin
  dosage: 162mg
  route_of_administration: Topical
  start_date: '2024-06-13'
  indication_for_use: Hypercholesterolemia
  drug_class: Statin
  end_date: '2024-08-15'
adverse_reactions:
- symptom_name: Stevens-Johnson syndrome
  onset_date: '2024-07-03'
  severity: Life-threatening
  outcome: Not Recovered
  intervention_required: true
- symptom_name: Diarrhea
  onset_date: '2024-07-03'
  severity: Mild
  outcome: Unknown
  intervention_required: true
  intervention_details: Prescribed sense and advised product.
- symptom_name: Dizziness
  onset_date: '2024-07-03'
  severity: Severe
  outcome: Recovered
  intervention_required: true
  intervention_details: Prescribed them and advised its.
- symptom_name: Somnolence
  onset_date: '2024-07-03'
  severity: Mild
  outcome: Not Recovered
  intervention_required: false
- symptom_name: Headache
  onset_date: '2024-07-03'
  severity: Life-threatening
  outcome: Fatal
  intervention_required: false
causality_assessment:
  assessment_conclusion: Probable
  dechallenge_rechallenge: Negative dechallenge
reporting_facility: Evans-Lopez Medical Center
reporter_type: Pharmacist
notes: Art popular speech same when health data. Continue drop ten thing whether modern
  attack. Produce hundred whom exist appear mention rock.
