<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2025-237
Date of Submission: 2025-04-04

This report was submitted by a Patient from Bauer, George and Garcia Medical Center concerning patient ANON-PX-5590. The subject is a 18-year-old male with a significant medical history including hypertension, osteoarthritis. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Lisinopril (ACE inhibitor) administered via the Topical route at a dosage of 224mg, initiated on 2025-02-11 for Hypertension with the course ongoing.

On approximately 2025-03-12, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Anaphylaxis, Headache, Dizziness. The Anaphylaxis was classified as Mild in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovering'. The Headache was classified as Moderate in severity. This necessitated clinical intervention. The documented action was: Prescribed several and advised rich. The current patient status regarding this symptom is 'Not Recovered'. The Dizziness was classified as Mild in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Not Recovered'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. A Naranjo score of 9 was calculated, The assessment concluded the relationship was 'Highly Probable'. Dechallenge/Rechallenge status was noted as: 'Positive rechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Administration center the fast behind cup affect weight. Maybe along knowledge range mission. Father call outside full product.</data>
report_id: ADR-2025-237
report_date: '2025-04-04'
patient_details:
  patient_id: ANON-PX-5590
  gender: Male
  relevant_history:
  - hypertension
  - osteoarthritis
  age_at_reaction: 18
suspected_drugs:
- drug_name: Lisinopril
  dosage: 224mg
  route_of_administration: Topical
  start_date: '2025-02-11'
  indication_for_use: Hypertension
  drug_class: ACE inhibitor
adverse_reactions:
- symptom_name: Anaphylaxis
  onset_date: '2025-03-12'
  severity: Mild
  outcome: Recovering
  intervention_required: false
- symptom_name: Headache
  onset_date: '2025-03-12'
  severity: Moderate
  outcome: Not Recovered
  intervention_required: true
  intervention_details: Prescribed several and advised rich.
- symptom_name: Dizziness
  onset_date: '2025-03-12'
  severity: Mild
  outcome: Not Recovered
  intervention_required: false
causality_assessment:
  assessment_conclusion: Highly Probable
  dechallenge_rechallenge: Positive rechallenge
  naranjo_score: 9
reporting_facility: Bauer, George and Garcia Medical Center
reporter_type: Patient
notes: Administration center the fast behind cup affect weight. Maybe along knowledge
  range mission. Father call outside full product.
