<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2025-916
Date of Submission: 2025-03-15

This report was submitted by a Other Healthcare Professional from Bowman, Nelson and Camacho Medical Center concerning patient ANON-PX-3507. The subject is a 90-year-old male with a significant medical history including type 2 diabetes, asthma, coronary artery disease, atrial fibrillation. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Atorvastatin (Statin) administered via the Intramuscular route at a dosage of 266mg, initiated on 2024-12-16 for Hypercholesterolemia and discontinued on 2025-02-05; Amoxicillin (Penicillin antibiotic) administered via the Intramuscular route at a dosage of 19mg, initiated on 2024-12-16 for Bacterial infection and discontinued on 2025-02-05.

On approximately 2025-01-09, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Pruritus, Stevens-Johnson syndrome. The Pruritus was classified as Severe in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Not Recovered'. The Stevens-Johnson syndrome was classified as Life-threatening in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovered'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. A Naranjo score of 8 was calculated, The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Negative dechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Again natural two sell occur. Painting present politics control word democratic hope window.</data>
report_id: ADR-2025-916
report_date: '2025-03-15'
patient_details:
  patient_id: ANON-PX-3507
  gender: Male
  relevant_history:
  - type 2 diabetes
  - asthma
  - coronary artery disease
  - atrial fibrillation
  age_at_reaction: 90
suspected_drugs:
- drug_name: Atorvastatin
  dosage: 266mg
  route_of_administration: Intramuscular
  start_date: '2024-12-16'
  indication_for_use: Hypercholesterolemia
  drug_class: Statin
  end_date: '2025-02-05'
- drug_name: Amoxicillin
  dosage: 19mg
  route_of_administration: Intramuscular
  start_date: '2024-12-16'
  indication_for_use: Bacterial infection
  drug_class: Penicillin antibiotic
  end_date: '2025-02-05'
adverse_reactions:
- symptom_name: Pruritus
  onset_date: '2025-01-09'
  severity: Severe
  outcome: Not Recovered
  intervention_required: false
- symptom_name: Stevens-Johnson syndrome
  onset_date: '2025-01-09'
  severity: Life-threatening
  outcome: Recovered
  intervention_required: false
causality_assessment:
  assessment_conclusion: Probable
  dechallenge_rechallenge: Negative dechallenge
  naranjo_score: 8
reporting_facility: Bowman, Nelson and Camacho Medical Center
reporter_type: Other Healthcare Professional
notes: Again natural two sell occur. Painting present politics control word democratic
  hope window.
