<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2025-208
Date of Submission: 2025-02-14

This report was submitted by a Pharmacist from Sullivan-Reynolds Medical Center concerning patient ANON-PX-5402. The subject is a 51-year-old female with a significant medical history including chronic kidney disease, seasonal allergies, coronary artery disease, migraines. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Warfarin (Anticoagulant) administered via the Subcutaneous route at a dosage of 457mg, initiated on 2025-02-03 for Thromboembolism prevention and discontinued on 2025-02-10; Levothyroxine (Thyroid hormone) administered via the Subcutaneous route at a dosage of 99mg, initiated on 2025-02-03 for Hypothyroidism and discontinued on 2025-02-10.

On approximately 2025-02-08, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Anaphylaxis, Diarrhea, Dizziness, Stevens-Johnson syndrome. The Anaphylaxis was classified as Life-threatening in severity. This necessitated clinical intervention. The current patient status regarding this symptom is 'Recovering'. The Diarrhea was classified as Severe in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Not Recovered'. The Dizziness was classified as Severe in severity. This necessitated clinical intervention. The documented action was: Prescribed growth and advised pull. The current patient status regarding this symptom is 'Fatal'. The Stevens-Johnson syndrome was classified as Mild in severity. This necessitated clinical intervention. The documented action was: Prescribed moment and advised grow. The current patient status regarding this symptom is 'Recovering'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Rechallenge not performed'. The on-site pharmacist concurred with the assessment during a routine case review. 

</data>
report_id: ADR-2025-208
report_date: '2025-02-14'
patient_details:
  patient_id: ANON-PX-5402
  gender: Female
  relevant_history:
  - chronic kidney disease
  - seasonal allergies
  - coronary artery disease
  - migraines
  age_at_reaction: 51
suspected_drugs:
- drug_name: Warfarin
  dosage: 457mg
  route_of_administration: Subcutaneous
  start_date: '2025-02-03'
  indication_for_use: Thromboembolism prevention
  drug_class: Anticoagulant
  end_date: '2025-02-10'
- drug_name: Levothyroxine
  dosage: 99mg
  route_of_administration: Subcutaneous
  start_date: '2025-02-03'
  indication_for_use: Hypothyroidism
  drug_class: Thyroid hormone
  end_date: '2025-02-10'
adverse_reactions:
- symptom_name: Anaphylaxis
  onset_date: '2025-02-08'
  severity: Life-threatening
  outcome: Recovering
  intervention_required: true
- symptom_name: Diarrhea
  onset_date: '2025-02-08'
  severity: Severe
  outcome: Not Recovered
  intervention_required: false
- symptom_name: Dizziness
  onset_date: '2025-02-08'
  severity: Severe
  outcome: Fatal
  intervention_required: true
  intervention_details: Prescribed growth and advised pull.
- symptom_name: Stevens-Johnson syndrome
  onset_date: '2025-02-08'
  severity: Mild
  outcome: Recovering
  intervention_required: true
  intervention_details: Prescribed moment and advised grow.
causality_assessment:
  assessment_conclusion: Probable
  dechallenge_rechallenge: Rechallenge not performed
reporting_facility: Sullivan-Reynolds Medical Center
reporter_type: Pharmacist
