<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2024-235
Date of Submission: 2024-12-06

This report was submitted by a Patient from Chen LLC Medical Center concerning patient ANON-PX-5922. The subject is a 69-year-old other with a significant medical history including hypertension, coronary artery disease, chronic kidney disease. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Gabapentin (Anticonvulsant) administered via the Intravenous route at a dosage of 45mg, initiated on 2024-11-23 for Neuropathic pain with the course ongoing.

On approximately 2024-12-02, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Hepatotoxicity, Stevens-Johnson syndrome, Nausea, Maculopapular Rash, Headache. The Hepatotoxicity was classified as Life-threatening in severity. This necessitated clinical intervention. The current patient status regarding this symptom is 'Recovering'. The Stevens-Johnson syndrome was classified as Moderate in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Unknown'. The Nausea was classified as Mild in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Unknown'. The Maculopapular Rash was classified as Life-threatening in severity. This necessitated clinical intervention. The current patient status regarding this symptom is 'Recovered'. The Headache was classified as Moderate in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Fatal'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. A Naranjo score of 10 was calculated, The assessment concluded the relationship was 'Highly Probable'. Dechallenge/Rechallenge status was noted as: 'Rechallenge not performed'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Hundred century Republican prevent understand event laugh. Although both song class wait material impact. Over high continue store quickly task whom.</data>
report_id: ADR-2024-235
report_date: '2024-12-06'
patient_details:
  patient_id: ANON-PX-5922
  gender: Other
  relevant_history:
  - hypertension
  - coronary artery disease
  - chronic kidney disease
  age_at_reaction: 69
suspected_drugs:
- drug_name: Gabapentin
  dosage: 45mg
  route_of_administration: Intravenous
  start_date: '2024-11-23'
  indication_for_use: Neuropathic pain
  drug_class: Anticonvulsant
adverse_reactions:
- symptom_name: Hepatotoxicity
  onset_date: '2024-12-02'
  severity: Life-threatening
  outcome: Recovering
  intervention_required: true
- symptom_name: Stevens-Johnson syndrome
  onset_date: '2024-12-02'
  severity: Moderate
  outcome: Unknown
  intervention_required: false
- symptom_name: Nausea
  onset_date: '2024-12-02'
  severity: Mild
  outcome: Unknown
  intervention_required: false
- symptom_name: Maculopapular Rash
  onset_date: '2024-12-02'
  severity: Life-threatening
  outcome: Recovered
  intervention_required: true
- symptom_name: Headache
  onset_date: '2024-12-02'
  severity: Moderate
  outcome: Fatal
  intervention_required: false
causality_assessment:
  assessment_conclusion: Highly Probable
  dechallenge_rechallenge: Rechallenge not performed
  naranjo_score: 10
reporting_facility: Chen LLC Medical Center
reporter_type: Patient
notes: Hundred century Republican prevent understand event laugh. Although both song
  class wait material impact. Over high continue store quickly task whom.
