<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2025-324
Date of Submission: 2025-02-06

This report was submitted by a Nurse from Stein and Sons Medical Center concerning patient ANON-PX-9269. The subject is an adult female with a significant medical history including osteoarthritis, chronic kidney disease, atrial fibrillation. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Sertraline administered via the Intravenous route at a dosage of 344mg, initiated on 2024-11-12 for Major depressive disorder with the course ongoing; Lisinopril (ACE inhibitor) administered via the Intravenous route at a dosage of 248mg, initiated on 2024-11-12 for Hypertension with the course ongoing.

On approximately 2024-11-27, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Nausea, Anaphylaxis, Diarrhea, Dizziness. The Nausea was classified as Severe in severity. This necessitated clinical intervention. The documented action was: Prescribed interesting and advised theory. The current patient status regarding this symptom is 'Unknown'. The Anaphylaxis was classified as Severe in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Unknown'. The Diarrhea was classified as Moderate in severity. This necessitated clinical intervention. The current patient status regarding this symptom is 'Fatal'. The Dizziness was classified as Moderate in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovering'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. A Naranjo score of 10 was calculated, The assessment concluded the relationship was 'Highly Probable'. Dechallenge/Rechallenge status was noted as: 'Not applicable'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Shake opportunity interview young. Grow thus character discover. Animal by theory prepare work.</data>
report_id: ADR-2025-324
report_date: '2025-02-06'
patient_details:
  patient_id: ANON-PX-9269
  gender: Female
  relevant_history:
  - osteoarthritis
  - chronic kidney disease
  - atrial fibrillation
suspected_drugs:
- drug_name: Sertraline
  dosage: 344mg
  route_of_administration: Intravenous
  start_date: '2024-11-12'
  indication_for_use: Major depressive disorder
- drug_name: Lisinopril
  dosage: 248mg
  route_of_administration: Intravenous
  start_date: '2024-11-12'
  indication_for_use: Hypertension
  drug_class: ACE inhibitor
adverse_reactions:
- symptom_name: Nausea
  onset_date: '2024-11-27'
  severity: Severe
  outcome: Unknown
  intervention_required: true
  intervention_details: Prescribed interesting and advised theory.
- symptom_name: Anaphylaxis
  onset_date: '2024-11-27'
  severity: Severe
  outcome: Unknown
  intervention_required: false
- symptom_name: Diarrhea
  onset_date: '2024-11-27'
  severity: Moderate
  outcome: Fatal
  intervention_required: true
- symptom_name: Dizziness
  onset_date: '2024-11-27'
  severity: Moderate
  outcome: Recovering
  intervention_required: false
causality_assessment:
  assessment_conclusion: Highly Probable
  dechallenge_rechallenge: Not applicable
  naranjo_score: 10
reporting_facility: Stein and Sons Medical Center
reporter_type: Nurse
notes: Shake opportunity interview young. Grow thus character discover. Animal by
  theory prepare work.
