<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2025-897
Date of Submission: 2025-01-21

This report was submitted by a Nurse from Carr, Gordon and Mitchell Medical Center concerning patient ANON-PX-7372. The subject is a 61-year-old male with a significant medical history including coronary artery disease, asthma, osteoarthritis. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Levothyroxine administered via the Intramuscular route at a dosage of 375mg, initiated on 2024-11-26 for Hypothyroidism and discontinued on 2024-12-15; Amoxicillin administered via the Intravenous route at a dosage of 47mg, initiated on 2024-11-26 for Bacterial infection and discontinued on 2024-12-15.

On approximately 2024-12-09, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Vomiting, Somnolence, Anaphylaxis. The Vomiting was classified as Life-threatening in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovering'. The Somnolence was classified as Mild in severity. This necessitated clinical intervention. The documented action was: Prescribed social and advised account. The current patient status regarding this symptom is 'Recovering'. The Anaphylaxis was classified as Mild in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovered'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Positive rechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Difference remember nearly report program. Sport Congress again her. Today shake national send oil.</data>
report_id: ADR-2025-897
report_date: '2025-01-21'
patient_details:
  patient_id: ANON-PX-7372
  gender: Male
  relevant_history:
  - coronary artery disease
  - asthma
  - osteoarthritis
  age_at_reaction: 61
suspected_drugs:
- drug_name: Levothyroxine
  dosage: 375mg
  route_of_administration: Intramuscular
  start_date: '2024-11-26'
  indication_for_use: Hypothyroidism
  end_date: '2024-12-15'
- drug_name: Amoxicillin
  dosage: 47mg
  route_of_administration: Intravenous
  start_date: '2024-11-26'
  indication_for_use: Bacterial infection
  end_date: '2024-12-15'
adverse_reactions:
- symptom_name: Vomiting
  onset_date: '2024-12-09'
  severity: Life-threatening
  outcome: Recovering
  intervention_required: false
- symptom_name: Somnolence
  onset_date: '2024-12-09'
  severity: Mild
  outcome: Recovering
  intervention_required: true
  intervention_details: Prescribed social and advised account.
- symptom_name: Anaphylaxis
  onset_date: '2024-12-09'
  severity: Mild
  outcome: Recovered
  intervention_required: false
causality_assessment:
  assessment_conclusion: Probable
  dechallenge_rechallenge: Positive rechallenge
reporting_facility: Carr, Gordon and Mitchell Medical Center
reporter_type: Nurse
notes: Difference remember nearly report program. Sport Congress again her. Today
  shake national send oil.
