<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2025-158
Date of Submission: 2025-07-29

This report was submitted by a Nurse from Perez LLC Medical Center concerning patient ANON-PX-7219. The subject is a 55-year-old other with a significant medical history including asthma, hypertension. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Omeprazole (Proton-pump inhibitor) administered via the Subcutaneous route at a dosage of 349mg, initiated on 2025-06-02 for Gastroesophageal reflux disease with the course ongoing; Sertraline (SSRI) administered via the Intravenous route at a dosage of 370mg, initiated on 2025-06-02 for Major depressive disorder with the course ongoing.

On approximately 2025-07-17, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Headache, Nausea. The Headache was classified as Life-threatening in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovered'. The Nausea was classified as Moderate in severity. This necessitated clinical intervention. The documented action was: Prescribed speak and advised option. The current patient status regarding this symptom is 'Not Recovered'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. A Naranjo score of 3 was calculated, The assessment concluded the relationship was 'Possible'. Dechallenge/Rechallenge status was noted as: 'Rechallenge not performed'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Official stuff well foot team. Size although forward perhaps.</data>
report_id: ADR-2025-158
report_date: '2025-07-29'
patient_details:
  patient_id: ANON-PX-7219
  gender: Other
  relevant_history:
  - asthma
  - hypertension
  age_at_reaction: 55
suspected_drugs:
- drug_name: Omeprazole
  dosage: 349mg
  route_of_administration: Subcutaneous
  start_date: '2025-06-02'
  indication_for_use: Gastroesophageal reflux disease
  drug_class: Proton-pump inhibitor
- drug_name: Sertraline
  dosage: 370mg
  route_of_administration: Intravenous
  start_date: '2025-06-02'
  indication_for_use: Major depressive disorder
  drug_class: SSRI
adverse_reactions:
- symptom_name: Headache
  onset_date: '2025-07-17'
  severity: Life-threatening
  outcome: Recovered
  intervention_required: false
- symptom_name: Nausea
  onset_date: '2025-07-17'
  severity: Moderate
  outcome: Not Recovered
  intervention_required: true
  intervention_details: Prescribed speak and advised option.
causality_assessment:
  assessment_conclusion: Possible
  dechallenge_rechallenge: Rechallenge not performed
  naranjo_score: 3
reporting_facility: Perez LLC Medical Center
reporter_type: Nurse
notes: Official stuff well foot team. Size although forward perhaps.
