<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2025-988
Date of Submission: 2025-06-03

This report was submitted by a Pharmacist from Villa-Mcdonald Medical Center concerning patient ANON-PX-7163. The subject is a 23-year-old male with a significant medical history including asthma, coronary artery disease, seasonal allergies, anxiety. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Warfarin (Anticoagulant) administered via the Intramuscular route at a dosage of 320mg, initiated on 2025-03-14 for Thromboembolism prevention and discontinued on 2025-05-21; Sertraline administered via the Topical route at a dosage of 362mg, initiated on 2025-03-14 for Major depressive disorder and discontinued on 2025-05-21.

On approximately 2025-04-30, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Headache, Anaphylaxis, Stevens-Johnson syndrome. The Headache was classified as Mild in severity. This necessitated clinical intervention. The documented action was: Prescribed compare and advised there. The current patient status regarding this symptom is 'Not Recovered'. The Anaphylaxis was classified as Mild in severity. This necessitated clinical intervention. The documented action was: Prescribed cell and advised water. The current patient status regarding this symptom is 'Fatal'. The Stevens-Johnson syndrome was classified as Mild in severity. This necessitated clinical intervention. The documented action was: Prescribed product and advised time. The current patient status regarding this symptom is 'Recovered'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. A Naranjo score of 3 was calculated, The assessment concluded the relationship was 'Possible'. Dechallenge/Rechallenge status was noted as: 'Positive rechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Receive consider exist main them reason some nearly. Bill how mention ahead compare fire.</data>
report_id: ADR-2025-988
report_date: '2025-06-03'
patient_details:
  patient_id: ANON-PX-7163
  gender: Male
  relevant_history:
  - asthma
  - coronary artery disease
  - seasonal allergies
  - anxiety
  age_at_reaction: 23
suspected_drugs:
- drug_name: Warfarin
  dosage: 320mg
  route_of_administration: Intramuscular
  start_date: '2025-03-14'
  indication_for_use: Thromboembolism prevention
  drug_class: Anticoagulant
  end_date: '2025-05-21'
- drug_name: Sertraline
  dosage: 362mg
  route_of_administration: Topical
  start_date: '2025-03-14'
  indication_for_use: Major depressive disorder
  end_date: '2025-05-21'
adverse_reactions:
- symptom_name: Headache
  onset_date: '2025-04-30'
  severity: Mild
  outcome: Not Recovered
  intervention_required: true
  intervention_details: Prescribed compare and advised there.
- symptom_name: Anaphylaxis
  onset_date: '2025-04-30'
  severity: Mild
  outcome: Fatal
  intervention_required: true
  intervention_details: Prescribed cell and advised water.
- symptom_name: Stevens-Johnson syndrome
  onset_date: '2025-04-30'
  severity: Mild
  outcome: Recovered
  intervention_required: true
  intervention_details: Prescribed product and advised time.
causality_assessment:
  assessment_conclusion: Possible
  dechallenge_rechallenge: Positive rechallenge
  naranjo_score: 3
reporting_facility: Villa-Mcdonald Medical Center
reporter_type: Pharmacist
notes: Receive consider exist main them reason some nearly. Bill how mention ahead
  compare fire.
