<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2024-644
Date of Submission: 2024-12-12

This report was submitted by a Other Healthcare Professional from Brennan-Medina Medical Center concerning patient ANON-PX-5324. The subject is a 62-year-old other with a significant medical history including hypertension, asthma. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Amoxicillin (Penicillin antibiotic) administered via the Oral route at a dosage of 176mg, initiated on 2024-10-22 for Bacterial infection and discontinued on 2024-11-28; Atorvastatin (Statin) administered via the Subcutaneous route at a dosage of 14mg, initiated on 2024-10-22 for Hypercholesterolemia and discontinued on 2024-11-28.

On approximately 2024-10-29, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Vomiting, Pruritus. The Vomiting was classified as Severe in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Unknown'. The Pruritus was classified as Mild in severity. This necessitated clinical intervention. The documented action was: Prescribed do and advised again. The current patient status regarding this symptom is 'Recovered'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. A Naranjo score of 1 was calculated, The assessment concluded the relationship was 'Possible'. Dechallenge/Rechallenge status was noted as: 'Not applicable'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Individual game edge involve. Account draw pay southern attention grow.</data>
report_id: ADR-2024-644
report_date: '2024-12-12'
patient_details:
  patient_id: ANON-PX-5324
  gender: Other
  relevant_history:
  - hypertension
  - asthma
  age_at_reaction: 62
suspected_drugs:
- drug_name: Amoxicillin
  dosage: 176mg
  route_of_administration: Oral
  start_date: '2024-10-22'
  indication_for_use: Bacterial infection
  drug_class: Penicillin antibiotic
  end_date: '2024-11-28'
- drug_name: Atorvastatin
  dosage: 14mg
  route_of_administration: Subcutaneous
  start_date: '2024-10-22'
  indication_for_use: Hypercholesterolemia
  drug_class: Statin
  end_date: '2024-11-28'
adverse_reactions:
- symptom_name: Vomiting
  onset_date: '2024-10-29'
  severity: Severe
  outcome: Unknown
  intervention_required: false
- symptom_name: Pruritus
  onset_date: '2024-10-29'
  severity: Mild
  outcome: Recovered
  intervention_required: true
  intervention_details: Prescribed do and advised again.
causality_assessment:
  assessment_conclusion: Possible
  dechallenge_rechallenge: Not applicable
  naranjo_score: 1
reporting_facility: Brennan-Medina Medical Center
reporter_type: Other Healthcare Professional
notes: Individual game edge involve. Account draw pay southern attention grow.
