<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2025-819
Date of Submission: 2025-01-21

This report was submitted by a Physician from Smith, Fischer and Fox Medical Center concerning patient ANON-PX-8603. The subject is an adult male with a significant medical history including seasonal allergies, chronic kidney disease, atrial fibrillation. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Warfarin (Anticoagulant) administered via the Intravenous route at a dosage of 322mg, initiated on 2024-10-23 for Thromboembolism prevention and discontinued on 2025-01-15; Sertraline administered via the Intravenous route at a dosage of 154mg, initiated on 2024-10-23 for Major depressive disorder and discontinued on 2025-01-15.

On approximately 2025-01-11, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Nausea, Vomiting, Hepatotoxicity. The Nausea was classified as Moderate in severity. This necessitated clinical intervention. The documented action was: Prescribed religious and advised sea. The current patient status regarding this symptom is 'Unknown'. The Vomiting was classified as Mild in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovering'. The Hepatotoxicity was classified as Mild in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Fatal'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Not applicable'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Remember pass success toward news whether seek. Answer general parent kind.</data>
report_id: ADR-2025-819
report_date: '2025-01-21'
patient_details:
  patient_id: ANON-PX-8603
  gender: Male
  relevant_history:
  - seasonal allergies
  - chronic kidney disease
  - atrial fibrillation
suspected_drugs:
- drug_name: Warfarin
  dosage: 322mg
  route_of_administration: Intravenous
  start_date: '2024-10-23'
  indication_for_use: Thromboembolism prevention
  drug_class: Anticoagulant
  end_date: '2025-01-15'
- drug_name: Sertraline
  dosage: 154mg
  route_of_administration: Intravenous
  start_date: '2024-10-23'
  indication_for_use: Major depressive disorder
  end_date: '2025-01-15'
adverse_reactions:
- symptom_name: Nausea
  onset_date: '2025-01-11'
  severity: Moderate
  outcome: Unknown
  intervention_required: true
  intervention_details: Prescribed religious and advised sea.
- symptom_name: Vomiting
  onset_date: '2025-01-11'
  severity: Mild
  outcome: Recovering
  intervention_required: false
- symptom_name: Hepatotoxicity
  onset_date: '2025-01-11'
  severity: Mild
  outcome: Fatal
  intervention_required: false
causality_assessment:
  assessment_conclusion: Probable
  dechallenge_rechallenge: Not applicable
reporting_facility: Smith, Fischer and Fox Medical Center
reporter_type: Physician
notes: Remember pass success toward news whether seek. Answer general parent kind.
