<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2025-984
Date of Submission: 2025-03-22

This report was submitted by a Other Healthcare Professional from Green, Cameron and Crawford Medical Center concerning patient ANON-PX-8058. The subject is a 38-year-old male with a significant medical history including type 2 diabetes, osteoarthritis, atrial fibrillation, hypertension. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Atorvastatin (Statin) administered via the Oral route at a dosage of 450mg, initiated on 2024-12-30 for Hypercholesterolemia with the course ongoing.

On approximately 2025-01-04, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Hepatotoxicity, Pruritus, Vomiting, Angioedema. The Hepatotoxicity was classified as Severe in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Fatal'. The Pruritus was classified as Mild in severity. This necessitated clinical intervention. The documented action was: Prescribed event and advised he. The current patient status regarding this symptom is 'Recovering'. The Vomiting was classified as Life-threatening in severity. This necessitated clinical intervention. The current patient status regarding this symptom is 'Unknown'. The Angioedema was classified as Mild in severity. This necessitated clinical intervention. The documented action was: Prescribed politics and advised if. The current patient status regarding this symptom is 'Fatal'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Positive dechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: To even necessary great can. Play relationship seven. Situation pick along respond stand.</data>
report_id: ADR-2025-984
report_date: '2025-03-22'
patient_details:
  patient_id: ANON-PX-8058
  gender: Male
  relevant_history:
  - type 2 diabetes
  - osteoarthritis
  - atrial fibrillation
  - hypertension
  age_at_reaction: 38
suspected_drugs:
- drug_name: Atorvastatin
  dosage: 450mg
  route_of_administration: Oral
  start_date: '2024-12-30'
  indication_for_use: Hypercholesterolemia
  drug_class: Statin
adverse_reactions:
- symptom_name: Hepatotoxicity
  onset_date: '2025-01-04'
  severity: Severe
  outcome: Fatal
  intervention_required: false
- symptom_name: Pruritus
  onset_date: '2025-01-04'
  severity: Mild
  outcome: Recovering
  intervention_required: true
  intervention_details: Prescribed event and advised he.
- symptom_name: Vomiting
  onset_date: '2025-01-04'
  severity: Life-threatening
  outcome: Unknown
  intervention_required: true
- symptom_name: Angioedema
  onset_date: '2025-01-04'
  severity: Mild
  outcome: Fatal
  intervention_required: true
  intervention_details: Prescribed politics and advised if.
causality_assessment:
  assessment_conclusion: Probable
  dechallenge_rechallenge: Positive dechallenge
reporting_facility: Green, Cameron and Crawford Medical Center
reporter_type: Other Healthcare Professional
notes: To even necessary great can. Play relationship seven. Situation pick along
  respond stand.
