<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2025-366
Date of Submission: 2025-06-21

This report was submitted by a Nurse from Mckinney Inc Medical Center concerning patient ANON-PX-3028. The subject is an adult male with a significant medical history including hypertension, migraines, atrial fibrillation. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Amoxicillin administered via the Intravenous route at a dosage of 273mg, initiated on 2025-05-28 for Bacterial infection with the course ongoing.

On approximately 2025-06-16, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Vomiting, Somnolence, Headache, Stevens-Johnson syndrome. The Vomiting was classified as Moderate in severity. This necessitated clinical intervention. The documented action was: Prescribed medical and advised specific. The current patient status regarding this symptom is 'Fatal'. The Somnolence was classified as Severe in severity. This necessitated clinical intervention. The current patient status regarding this symptom is 'Not Recovered'. The Headache was classified as Life-threatening in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Not Recovered'. The Stevens-Johnson syndrome was classified as Moderate in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovered'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. A Naranjo score of 4 was calculated, The assessment concluded the relationship was 'Possible'. Dechallenge/Rechallenge status was noted as: 'Positive rechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Listen shake piece. Training two somebody low attention five. Along court mission week wall letter about.</data>
report_id: ADR-2025-366
report_date: '2025-06-21'
patient_details:
  patient_id: ANON-PX-3028
  gender: Male
  relevant_history:
  - hypertension
  - migraines
  - atrial fibrillation
suspected_drugs:
- drug_name: Amoxicillin
  dosage: 273mg
  route_of_administration: Intravenous
  start_date: '2025-05-28'
  indication_for_use: Bacterial infection
adverse_reactions:
- symptom_name: Vomiting
  onset_date: '2025-06-16'
  severity: Moderate
  outcome: Fatal
  intervention_required: true
  intervention_details: Prescribed medical and advised specific.
- symptom_name: Somnolence
  onset_date: '2025-06-16'
  severity: Severe
  outcome: Not Recovered
  intervention_required: true
- symptom_name: Headache
  onset_date: '2025-06-16'
  severity: Life-threatening
  outcome: Not Recovered
  intervention_required: false
- symptom_name: Stevens-Johnson syndrome
  onset_date: '2025-06-16'
  severity: Moderate
  outcome: Recovered
  intervention_required: false
causality_assessment:
  assessment_conclusion: Possible
  dechallenge_rechallenge: Positive rechallenge
  naranjo_score: 4
reporting_facility: Mckinney Inc Medical Center
reporter_type: Nurse
notes: Listen shake piece. Training two somebody low attention five. Along court mission
  week wall letter about.
