<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2024-271
Date of Submission: 2024-10-12

This report was submitted by a Nurse from Smith LLC Medical Center concerning patient ANON-PX-7277. The subject is an adult female with a significant medical history including asthma, anxiety, atrial fibrillation, type 2 diabetes. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Gabapentin administered via the Oral route at a dosage of 107mg, initiated on 2024-09-18 for Neuropathic pain with the course ongoing; Ibuprofen administered via the Topical route at a dosage of 214mg, initiated on 2024-09-18 for Pain and inflammation with the course ongoing.

On approximately 2024-09-20, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Pruritus, Nausea. The Pruritus was classified as Mild in severity. This necessitated clinical intervention. The documented action was: Prescribed game and advised appear. The current patient status regarding this symptom is 'Unknown'. The Nausea was classified as Life-threatening in severity. This necessitated clinical intervention. The documented action was: Prescribed old and advised send. The current patient status regarding this symptom is 'Fatal'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Rechallenge not performed'. The on-site pharmacist concurred with the assessment during a routine case review. 

</data>
report_id: ADR-2024-271
report_date: '2024-10-12'
patient_details:
  patient_id: ANON-PX-7277
  gender: Female
  relevant_history:
  - asthma
  - anxiety
  - atrial fibrillation
  - type 2 diabetes
suspected_drugs:
- drug_name: Gabapentin
  dosage: 107mg
  route_of_administration: Oral
  start_date: '2024-09-18'
  indication_for_use: Neuropathic pain
- drug_name: Ibuprofen
  dosage: 214mg
  route_of_administration: Topical
  start_date: '2024-09-18'
  indication_for_use: Pain and inflammation
adverse_reactions:
- symptom_name: Pruritus
  onset_date: '2024-09-20'
  severity: Mild
  outcome: Unknown
  intervention_required: true
  intervention_details: Prescribed game and advised appear.
- symptom_name: Nausea
  onset_date: '2024-09-20'
  severity: Life-threatening
  outcome: Fatal
  intervention_required: true
  intervention_details: Prescribed old and advised send.
causality_assessment:
  assessment_conclusion: Probable
  dechallenge_rechallenge: Rechallenge not performed
reporting_facility: Smith LLC Medical Center
reporter_type: Nurse
