<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2024-761
Date of Submission: 2024-09-27

This report was submitted by a Physician from Huffman-Medina Medical Center concerning patient ANON-PX-8747. The subject is a 77-year-old female with a significant medical history including type 2 diabetes, coronary artery disease. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Sertraline (SSRI) administered via the Topical route at a dosage of 273mg, initiated on 2024-07-14 for Major depressive disorder and discontinued on 2024-08-30.

On approximately 2024-07-18, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Vomiting, Dizziness, Diarrhea, Headache. The Vomiting was classified as Life-threatening in severity. This necessitated clinical intervention. The documented action was: Prescribed help and advised build. The current patient status regarding this symptom is 'Recovering'. The Dizziness was classified as Severe in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovered'. The Diarrhea was classified as Severe in severity. This necessitated clinical intervention. The documented action was: Prescribed nothing and advised business. The current patient status regarding this symptom is 'Unknown'. The Headache was classified as Moderate in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovering'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. A Naranjo score of 2 was calculated, The assessment concluded the relationship was 'Possible'. Dechallenge/Rechallenge status was noted as: 'Positive rechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Election guy hear rather enough. Only image onto past.</data>
report_id: ADR-2024-761
report_date: '2024-09-27'
patient_details:
  patient_id: ANON-PX-8747
  gender: Female
  relevant_history:
  - type 2 diabetes
  - coronary artery disease
  age_at_reaction: 77
suspected_drugs:
- drug_name: Sertraline
  dosage: 273mg
  route_of_administration: Topical
  start_date: '2024-07-14'
  indication_for_use: Major depressive disorder
  drug_class: SSRI
  end_date: '2024-08-30'
adverse_reactions:
- symptom_name: Vomiting
  onset_date: '2024-07-18'
  severity: Life-threatening
  outcome: Recovering
  intervention_required: true
  intervention_details: Prescribed help and advised build.
- symptom_name: Dizziness
  onset_date: '2024-07-18'
  severity: Severe
  outcome: Recovered
  intervention_required: false
- symptom_name: Diarrhea
  onset_date: '2024-07-18'
  severity: Severe
  outcome: Unknown
  intervention_required: true
  intervention_details: Prescribed nothing and advised business.
- symptom_name: Headache
  onset_date: '2024-07-18'
  severity: Moderate
  outcome: Recovering
  intervention_required: false
causality_assessment:
  assessment_conclusion: Possible
  dechallenge_rechallenge: Positive rechallenge
  naranjo_score: 2
reporting_facility: Huffman-Medina Medical Center
reporter_type: Physician
notes: Election guy hear rather enough. Only image onto past.
