<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2025-566
Date of Submission: 2025-02-18

This report was submitted by a Other Healthcare Professional from Parker Group Medical Center concerning patient ANON-PX-5679. The subject is a 73-year-old female with a significant medical history including osteoarthritis, type 2 diabetes, coronary artery disease, seasonal allergies. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Warfarin (Anticoagulant) administered via the Intravenous route at a dosage of 117mg, initiated on 2024-12-15 for Thromboembolism prevention with the course ongoing.

On approximately 2025-02-01, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Stevens-Johnson syndrome, Headache, Hepatotoxicity, Anaphylaxis, Maculopapular Rash. The Stevens-Johnson syndrome was classified as Severe in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovered'. The Headache was classified as Moderate in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Not Recovered'. The Hepatotoxicity was classified as Mild in severity. This necessitated clinical intervention. The documented action was: Prescribed low and advised society. The current patient status regarding this symptom is 'Fatal'. The Anaphylaxis was classified as Life-threatening in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Fatal'. The Maculopapular Rash was classified as Mild in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Unknown'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. A Naranjo score of 10 was calculated, The assessment concluded the relationship was 'Highly Probable'. Dechallenge/Rechallenge status was noted as: 'Rechallenge not performed'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Floor grow there military nearly. Amount natural report than nor read.</data>
report_id: ADR-2025-566
report_date: '2025-02-18'
patient_details:
  patient_id: ANON-PX-5679
  gender: Female
  relevant_history:
  - osteoarthritis
  - type 2 diabetes
  - coronary artery disease
  - seasonal allergies
  age_at_reaction: 73
suspected_drugs:
- drug_name: Warfarin
  dosage: 117mg
  route_of_administration: Intravenous
  start_date: '2024-12-15'
  indication_for_use: Thromboembolism prevention
  drug_class: Anticoagulant
adverse_reactions:
- symptom_name: Stevens-Johnson syndrome
  onset_date: '2025-02-01'
  severity: Severe
  outcome: Recovered
  intervention_required: false
- symptom_name: Headache
  onset_date: '2025-02-01'
  severity: Moderate
  outcome: Not Recovered
  intervention_required: false
- symptom_name: Hepatotoxicity
  onset_date: '2025-02-01'
  severity: Mild
  outcome: Fatal
  intervention_required: true
  intervention_details: Prescribed low and advised society.
- symptom_name: Anaphylaxis
  onset_date: '2025-02-01'
  severity: Life-threatening
  outcome: Fatal
  intervention_required: false
- symptom_name: Maculopapular Rash
  onset_date: '2025-02-01'
  severity: Mild
  outcome: Unknown
  intervention_required: false
causality_assessment:
  assessment_conclusion: Highly Probable
  dechallenge_rechallenge: Rechallenge not performed
  naranjo_score: 10
reporting_facility: Parker Group Medical Center
reporter_type: Other Healthcare Professional
notes: Floor grow there military nearly. Amount natural report than nor read.
