<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2025-175
Date of Submission: 2025-01-31

This report was submitted by a Nurse from Ali-Bailey Medical Center concerning patient ANON-PX-7098. The subject is an adult female with a significant medical history including hypertension, type 2 diabetes, coronary artery disease, atrial fibrillation. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Omeprazole (Proton-pump inhibitor) administered via the Oral route at a dosage of 434mg, initiated on 2024-12-28 for Gastroesophageal reflux disease and discontinued on 2025-01-18.

On approximately 2025-01-07, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Pruritus, Somnolence. The Pruritus was classified as Moderate in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Fatal'. The Somnolence was classified as Mild in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Fatal'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. A Naranjo score of 7 was calculated, The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Negative dechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Front fish sing threat. Ago local police change yeah everyone me.</data>
report_id: ADR-2025-175
report_date: '2025-01-31'
patient_details:
  patient_id: ANON-PX-7098
  gender: Female
  relevant_history:
  - hypertension
  - type 2 diabetes
  - coronary artery disease
  - atrial fibrillation
suspected_drugs:
- drug_name: Omeprazole
  dosage: 434mg
  route_of_administration: Oral
  start_date: '2024-12-28'
  indication_for_use: Gastroesophageal reflux disease
  drug_class: Proton-pump inhibitor
  end_date: '2025-01-18'
adverse_reactions:
- symptom_name: Pruritus
  onset_date: '2025-01-07'
  severity: Moderate
  outcome: Fatal
  intervention_required: false
- symptom_name: Somnolence
  onset_date: '2025-01-07'
  severity: Mild
  outcome: Fatal
  intervention_required: false
causality_assessment:
  assessment_conclusion: Probable
  dechallenge_rechallenge: Negative dechallenge
  naranjo_score: 7
reporting_facility: Ali-Bailey Medical Center
reporter_type: Nurse
notes: Front fish sing threat. Ago local police change yeah everyone me.
