<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2024-744
Date of Submission: 2024-08-22

This report was submitted by a Physician from Jones LLC Medical Center concerning patient ANON-PX-4769. The subject is a 48-year-old female with a significant medical history including asthma, migraines. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Warfarin (Anticoagulant) administered via the Intramuscular route at a dosage of 354mg, initiated on 2024-08-09 for Thromboembolism prevention with the course ongoing; Atorvastatin (Statin) administered via the Intramuscular route at a dosage of 401mg, initiated on 2024-08-09 for Hypercholesterolemia with the course ongoing.

On approximately 2024-08-18, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Hepatotoxicity, Somnolence, Angioedema, Anaphylaxis, Headache. The Hepatotoxicity was classified as Severe in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Not Recovered'. The Somnolence was classified as Life-threatening in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovering'. The Angioedema was classified as Severe in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovering'. The Anaphylaxis was classified as Severe in severity. This necessitated clinical intervention. The documented action was: Prescribed player and advised country. The current patient status regarding this symptom is 'Recovered'. The Headache was classified as Severe in severity. This necessitated clinical intervention. The documented action was: Prescribed west and advised reality. The current patient status regarding this symptom is 'Unknown'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. A Naranjo score of 5 was calculated, The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Rechallenge not performed'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Ahead human still model. Go great successful serve.</data>
report_id: ADR-2024-744
report_date: '2024-08-22'
patient_details:
  patient_id: ANON-PX-4769
  gender: Female
  relevant_history:
  - asthma
  - migraines
  age_at_reaction: 48
suspected_drugs:
- drug_name: Warfarin
  dosage: 354mg
  route_of_administration: Intramuscular
  start_date: '2024-08-09'
  indication_for_use: Thromboembolism prevention
  drug_class: Anticoagulant
- drug_name: Atorvastatin
  dosage: 401mg
  route_of_administration: Intramuscular
  start_date: '2024-08-09'
  indication_for_use: Hypercholesterolemia
  drug_class: Statin
adverse_reactions:
- symptom_name: Hepatotoxicity
  onset_date: '2024-08-18'
  severity: Severe
  outcome: Not Recovered
  intervention_required: false
- symptom_name: Somnolence
  onset_date: '2024-08-18'
  severity: Life-threatening
  outcome: Recovering
  intervention_required: false
- symptom_name: Angioedema
  onset_date: '2024-08-18'
  severity: Severe
  outcome: Recovering
  intervention_required: false
- symptom_name: Anaphylaxis
  onset_date: '2024-08-18'
  severity: Severe
  outcome: Recovered
  intervention_required: true
  intervention_details: Prescribed player and advised country.
- symptom_name: Headache
  onset_date: '2024-08-18'
  severity: Severe
  outcome: Unknown
  intervention_required: true
  intervention_details: Prescribed west and advised reality.
causality_assessment:
  assessment_conclusion: Probable
  dechallenge_rechallenge: Rechallenge not performed
  naranjo_score: 5
reporting_facility: Jones LLC Medical Center
reporter_type: Physician
notes: Ahead human still model. Go great successful serve.
