<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2025-269
Date of Submission: 2025-06-01

This report was submitted by a Pharmacist from Baker, Collins and Cabrera Medical Center concerning patient ANON-PX-1910. The subject is a 52-year-old female with a significant medical history including anxiety, seasonal allergies, atrial fibrillation. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Gabapentin (Anticonvulsant) administered via the Topical route at a dosage of 394mg, initiated on 2025-03-12 for Neuropathic pain and discontinued on 2025-05-25; Levothyroxine administered via the Intravenous route at a dosage of 201mg, initiated on 2025-03-12 for Hypothyroidism and discontinued on 2025-05-25.

On approximately 2025-04-18, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Angioedema, Hepatotoxicity, Headache, Vomiting. The Angioedema was classified as Severe in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovered'. The Hepatotoxicity was classified as Mild in severity. This necessitated clinical intervention. The documented action was: Prescribed deep and advised machine. The current patient status regarding this symptom is 'Recovered'. The Headache was classified as Mild in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Not Recovered'. The Vomiting was classified as Severe in severity. This necessitated clinical intervention. The documented action was: Prescribed line and advised agency. The current patient status regarding this symptom is 'Fatal'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Not applicable'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Way late ability. Girl here summer television war.</data>
report_id: ADR-2025-269
report_date: '2025-06-01'
patient_details:
  patient_id: ANON-PX-1910
  gender: Female
  relevant_history:
  - anxiety
  - seasonal allergies
  - atrial fibrillation
  age_at_reaction: 52
suspected_drugs:
- drug_name: Gabapentin
  dosage: 394mg
  route_of_administration: Topical
  start_date: '2025-03-12'
  indication_for_use: Neuropathic pain
  drug_class: Anticonvulsant
  end_date: '2025-05-25'
- drug_name: Levothyroxine
  dosage: 201mg
  route_of_administration: Intravenous
  start_date: '2025-03-12'
  indication_for_use: Hypothyroidism
  end_date: '2025-05-25'
adverse_reactions:
- symptom_name: Angioedema
  onset_date: '2025-04-18'
  severity: Severe
  outcome: Recovered
  intervention_required: false
- symptom_name: Hepatotoxicity
  onset_date: '2025-04-18'
  severity: Mild
  outcome: Recovered
  intervention_required: true
  intervention_details: Prescribed deep and advised machine.
- symptom_name: Headache
  onset_date: '2025-04-18'
  severity: Mild
  outcome: Not Recovered
  intervention_required: false
- symptom_name: Vomiting
  onset_date: '2025-04-18'
  severity: Severe
  outcome: Fatal
  intervention_required: true
  intervention_details: Prescribed line and advised agency.
causality_assessment:
  assessment_conclusion: Probable
  dechallenge_rechallenge: Not applicable
reporting_facility: Baker, Collins and Cabrera Medical Center
reporter_type: Pharmacist
notes: Way late ability. Girl here summer television war.
