<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2025-685
Date of Submission: 2025-08-12

This report was submitted by a Pharmacist from Mendez-Taylor Medical Center concerning patient ANON-PX-4767. The subject is a 75-year-old female with a significant medical history including anxiety, coronary artery disease. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Lisinopril administered via the Intravenous route at a dosage of 140mg, initiated on 2025-07-26 for Hypertension with the course ongoing; Amoxicillin (Penicillin antibiotic) administered via the Subcutaneous route at a dosage of 325mg, initiated on 2025-07-26 for Bacterial infection with the course ongoing.

On approximately 2025-08-06, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Headache, Pruritus, Angioedema, Stevens-Johnson syndrome. The Headache was classified as Moderate in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Not Recovered'. The Pruritus was classified as Mild in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Not Recovered'. The Angioedema was classified as Moderate in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Fatal'. The Stevens-Johnson syndrome was classified as Mild in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Fatal'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. A Naranjo score of 5 was calculated, The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Negative dechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Window fight dream what.</data>
report_id: ADR-2025-685
report_date: '2025-08-12'
patient_details:
  patient_id: ANON-PX-4767
  gender: Female
  relevant_history:
  - anxiety
  - coronary artery disease
  age_at_reaction: 75
suspected_drugs:
- drug_name: Lisinopril
  dosage: 140mg
  route_of_administration: Intravenous
  start_date: '2025-07-26'
  indication_for_use: Hypertension
- drug_name: Amoxicillin
  dosage: 325mg
  route_of_administration: Subcutaneous
  start_date: '2025-07-26'
  indication_for_use: Bacterial infection
  drug_class: Penicillin antibiotic
adverse_reactions:
- symptom_name: Headache
  onset_date: '2025-08-06'
  severity: Moderate
  outcome: Not Recovered
  intervention_required: false
- symptom_name: Pruritus
  onset_date: '2025-08-06'
  severity: Mild
  outcome: Not Recovered
  intervention_required: false
- symptom_name: Angioedema
  onset_date: '2025-08-06'
  severity: Moderate
  outcome: Fatal
  intervention_required: false
- symptom_name: Stevens-Johnson syndrome
  onset_date: '2025-08-06'
  severity: Mild
  outcome: Fatal
  intervention_required: false
causality_assessment:
  assessment_conclusion: Probable
  dechallenge_rechallenge: Negative dechallenge
  naranjo_score: 5
reporting_facility: Mendez-Taylor Medical Center
reporter_type: Pharmacist
notes: Window fight dream what.
