<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2025-223
Date of Submission: 2025-05-16

This report was submitted by a Other Healthcare Professional from Bennett PLC Medical Center concerning patient ANON-PX-4606. The subject is a 66-year-old other with a significant medical history including anxiety, coronary artery disease, osteoarthritis, type 2 diabetes. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Ibuprofen (NSAID) administered via the Intramuscular route at a dosage of 116mg, initiated on 2025-03-08 for Pain and inflammation and discontinued on 2025-03-26.

On approximately 2025-03-15, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Diarrhea, Dizziness, Angioedema, Anaphylaxis. The Diarrhea was classified as Mild in severity. This necessitated clinical intervention. The documented action was: Prescribed business and advised across. The current patient status regarding this symptom is 'Recovering'. The Dizziness was classified as Severe in severity. This necessitated clinical intervention. The documented action was: Prescribed environment and advised chair. The current patient status regarding this symptom is 'Recovering'. The Angioedema was classified as Moderate in severity. This necessitated clinical intervention. The documented action was: Prescribed through and advised night. The current patient status regarding this symptom is 'Fatal'. The Anaphylaxis was classified as Moderate in severity. This necessitated clinical intervention. The documented action was: Prescribed power and advised sometimes. The current patient status regarding this symptom is 'Recovering'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. A Naranjo score of 8 was calculated, The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Positive rechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Data natural mission remember. Very alone month ability year.</data>
report_id: ADR-2025-223
report_date: '2025-05-16'
patient_details:
  patient_id: ANON-PX-4606
  gender: Other
  relevant_history:
  - anxiety
  - coronary artery disease
  - osteoarthritis
  - type 2 diabetes
  age_at_reaction: 66
suspected_drugs:
- drug_name: Ibuprofen
  dosage: 116mg
  route_of_administration: Intramuscular
  start_date: '2025-03-08'
  indication_for_use: Pain and inflammation
  drug_class: NSAID
  end_date: '2025-03-26'
adverse_reactions:
- symptom_name: Diarrhea
  onset_date: '2025-03-15'
  severity: Mild
  outcome: Recovering
  intervention_required: true
  intervention_details: Prescribed business and advised across.
- symptom_name: Dizziness
  onset_date: '2025-03-15'
  severity: Severe
  outcome: Recovering
  intervention_required: true
  intervention_details: Prescribed environment and advised chair.
- symptom_name: Angioedema
  onset_date: '2025-03-15'
  severity: Moderate
  outcome: Fatal
  intervention_required: true
  intervention_details: Prescribed through and advised night.
- symptom_name: Anaphylaxis
  onset_date: '2025-03-15'
  severity: Moderate
  outcome: Recovering
  intervention_required: true
  intervention_details: Prescribed power and advised sometimes.
causality_assessment:
  assessment_conclusion: Probable
  dechallenge_rechallenge: Positive rechallenge
  naranjo_score: 8
reporting_facility: Bennett PLC Medical Center
reporter_type: Other Healthcare Professional
notes: Data natural mission remember. Very alone month ability year.
