<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2024-299
Date of Submission: 2024-10-15

This report was submitted by a Patient from Dougherty-Gonzalez Medical Center concerning patient ANON-PX-8756. The subject is a 49-year-old male with a significant medical history including anxiety, asthma, chronic kidney disease. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Ibuprofen administered via the Subcutaneous route at a dosage of 249mg, initiated on 2024-09-13 for Pain and inflammation with the course ongoing; Amoxicillin administered via the Subcutaneous route at a dosage of 251mg, initiated on 2024-09-13 for Bacterial infection with the course ongoing.

On approximately 2024-09-25, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Vomiting, Maculopapular Rash, Pruritus, Dizziness. The Vomiting was classified as Moderate in severity. This necessitated clinical intervention. The documented action was: Prescribed guy and advised a. The current patient status regarding this symptom is 'Fatal'. The Maculopapular Rash was classified as Moderate in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Unknown'. The Pruritus was classified as Mild in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovering'. The Dizziness was classified as Mild in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Not Recovered'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. A Naranjo score of 3 was calculated, The assessment concluded the relationship was 'Possible'. Dechallenge/Rechallenge status was noted as: 'Negative dechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. 

</data>
report_id: ADR-2024-299
report_date: '2024-10-15'
patient_details:
  patient_id: ANON-PX-8756
  gender: Male
  relevant_history:
  - anxiety
  - asthma
  - chronic kidney disease
  age_at_reaction: 49
suspected_drugs:
- drug_name: Ibuprofen
  dosage: 249mg
  route_of_administration: Subcutaneous
  start_date: '2024-09-13'
  indication_for_use: Pain and inflammation
- drug_name: Amoxicillin
  dosage: 251mg
  route_of_administration: Subcutaneous
  start_date: '2024-09-13'
  indication_for_use: Bacterial infection
adverse_reactions:
- symptom_name: Vomiting
  onset_date: '2024-09-25'
  severity: Moderate
  outcome: Fatal
  intervention_required: true
  intervention_details: Prescribed guy and advised a.
- symptom_name: Maculopapular Rash
  onset_date: '2024-09-25'
  severity: Moderate
  outcome: Unknown
  intervention_required: false
- symptom_name: Pruritus
  onset_date: '2024-09-25'
  severity: Mild
  outcome: Recovering
  intervention_required: false
- symptom_name: Dizziness
  onset_date: '2024-09-25'
  severity: Mild
  outcome: Not Recovered
  intervention_required: false
causality_assessment:
  assessment_conclusion: Possible
  dechallenge_rechallenge: Negative dechallenge
  naranjo_score: 3
reporting_facility: Dougherty-Gonzalez Medical Center
reporter_type: Patient
