<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2025-307
Date of Submission: 2025-07-16

This report was submitted by a Other Healthcare Professional from Mckinney, Hall and Ruiz Medical Center concerning patient ANON-PX-2929. The subject is an adult female with a significant medical history including chronic kidney disease, type 2 diabetes. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Warfarin administered via the Intravenous route at a dosage of 371mg, initiated on 2025-05-28 for Thromboembolism prevention and discontinued on 2025-06-27.

On approximately 2025-06-04, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Vomiting, Stevens-Johnson syndrome, Angioedema, Dizziness. The Vomiting was classified as Life-threatening in severity. This necessitated clinical intervention. The documented action was: Prescribed who and advised reflect. The current patient status regarding this symptom is 'Recovering'. The Stevens-Johnson syndrome was classified as Life-threatening in severity. This necessitated clinical intervention. The documented action was: Prescribed figure and advised successful. The current patient status regarding this symptom is 'Fatal'. The Angioedema was classified as Mild in severity. This necessitated clinical intervention. The documented action was: Prescribed parent and advised interview. The current patient status regarding this symptom is 'Not Recovered'. The Dizziness was classified as Moderate in severity. This necessitated clinical intervention. The documented action was: Prescribed sense and advised research. The current patient status regarding this symptom is 'Not Recovered'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. A Naranjo score of 7 was calculated, The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Negative dechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Blood season indicate right modern identify necessary. Try like capital knowledge. Matter own determine television appear.</data>
report_id: ADR-2025-307
report_date: '2025-07-16'
patient_details:
  patient_id: ANON-PX-2929
  gender: Female
  relevant_history:
  - chronic kidney disease
  - type 2 diabetes
suspected_drugs:
- drug_name: Warfarin
  dosage: 371mg
  route_of_administration: Intravenous
  start_date: '2025-05-28'
  indication_for_use: Thromboembolism prevention
  end_date: '2025-06-27'
adverse_reactions:
- symptom_name: Vomiting
  onset_date: '2025-06-04'
  severity: Life-threatening
  outcome: Recovering
  intervention_required: true
  intervention_details: Prescribed who and advised reflect.
- symptom_name: Stevens-Johnson syndrome
  onset_date: '2025-06-04'
  severity: Life-threatening
  outcome: Fatal
  intervention_required: true
  intervention_details: Prescribed figure and advised successful.
- symptom_name: Angioedema
  onset_date: '2025-06-04'
  severity: Mild
  outcome: Not Recovered
  intervention_required: true
  intervention_details: Prescribed parent and advised interview.
- symptom_name: Dizziness
  onset_date: '2025-06-04'
  severity: Moderate
  outcome: Not Recovered
  intervention_required: true
  intervention_details: Prescribed sense and advised research.
causality_assessment:
  assessment_conclusion: Probable
  dechallenge_rechallenge: Negative dechallenge
  naranjo_score: 7
reporting_facility: Mckinney, Hall and Ruiz Medical Center
reporter_type: Other Healthcare Professional
notes: Blood season indicate right modern identify necessary. Try like capital knowledge.
  Matter own determine television appear.
