<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2024-261
Date of Submission: 2024-12-07

This report was submitted by a Other Healthcare Professional from Taylor and Sons Medical Center concerning patient ANON-PX-8796. The subject is a 60-year-old male with a significant medical history including type 2 diabetes, asthma. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Lisinopril administered via the Subcutaneous route at a dosage of 188mg, initiated on 2024-10-16 for Hypertension with the course ongoing.

On approximately 2024-10-27, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Nausea, Hepatotoxicity, Angioedema, Diarrhea, Somnolence. The Nausea was classified as Life-threatening in severity. This necessitated clinical intervention. The documented action was: Prescribed art and advised magazine. The current patient status regarding this symptom is 'Fatal'. The Hepatotoxicity was classified as Mild in severity. This necessitated clinical intervention. The documented action was: Prescribed dark and advised when. The current patient status regarding this symptom is 'Unknown'. The Angioedema was classified as Life-threatening in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovering'. The Diarrhea was classified as Life-threatening in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Unknown'. The Somnolence was classified as Life-threatening in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Unknown'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Positive dechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Bar sing have success gas follow. Ball wind Republican family age than.</data>
report_id: ADR-2024-261
report_date: '2024-12-07'
patient_details:
  patient_id: ANON-PX-8796
  gender: Male
  relevant_history:
  - type 2 diabetes
  - asthma
  age_at_reaction: 60
suspected_drugs:
- drug_name: Lisinopril
  dosage: 188mg
  route_of_administration: Subcutaneous
  start_date: '2024-10-16'
  indication_for_use: Hypertension
adverse_reactions:
- symptom_name: Nausea
  onset_date: '2024-10-27'
  severity: Life-threatening
  outcome: Fatal
  intervention_required: true
  intervention_details: Prescribed art and advised magazine.
- symptom_name: Hepatotoxicity
  onset_date: '2024-10-27'
  severity: Mild
  outcome: Unknown
  intervention_required: true
  intervention_details: Prescribed dark and advised when.
- symptom_name: Angioedema
  onset_date: '2024-10-27'
  severity: Life-threatening
  outcome: Recovering
  intervention_required: false
- symptom_name: Diarrhea
  onset_date: '2024-10-27'
  severity: Life-threatening
  outcome: Unknown
  intervention_required: false
- symptom_name: Somnolence
  onset_date: '2024-10-27'
  severity: Life-threatening
  outcome: Unknown
  intervention_required: false
causality_assessment:
  assessment_conclusion: Probable
  dechallenge_rechallenge: Positive dechallenge
reporting_facility: Taylor and Sons Medical Center
reporter_type: Other Healthcare Professional
notes: Bar sing have success gas follow. Ball wind Republican family age than.
