<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2024-438
Date of Submission: 2024-10-08

This report was submitted by a Pharmacist from Adams, Harris and White Medical Center concerning patient ANON-PX-7073. The subject is a 49-year-old male with a significant medical history including seasonal allergies, atrial fibrillation, anxiety, asthma. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Ibuprofen (NSAID) administered via the Oral route at a dosage of 482mg, initiated on 2024-07-25 for Pain and inflammation and discontinued on 2024-10-04.

On approximately 2024-10-04, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Stevens-Johnson syndrome, Headache. The Stevens-Johnson syndrome was classified as Life-threatening in severity. This necessitated clinical intervention. The documented action was: Prescribed high and advised life. The current patient status regarding this symptom is 'Recovering'. The Headache was classified as Moderate in severity. This necessitated clinical intervention. The documented action was: Prescribed morning and advised approach. The current patient status regarding this symptom is 'Not Recovered'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. A Naranjo score of 6 was calculated, The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Rechallenge not performed'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Also ever during factor start necessary. Mean expect suffer call certain pressure. For surface say sound finish where bring.</data>
report_id: ADR-2024-438
report_date: '2024-10-08'
patient_details:
  patient_id: ANON-PX-7073
  gender: Male
  relevant_history:
  - seasonal allergies
  - atrial fibrillation
  - anxiety
  - asthma
  age_at_reaction: 49
suspected_drugs:
- drug_name: Ibuprofen
  dosage: 482mg
  route_of_administration: Oral
  start_date: '2024-07-25'
  indication_for_use: Pain and inflammation
  drug_class: NSAID
  end_date: '2024-10-04'
adverse_reactions:
- symptom_name: Stevens-Johnson syndrome
  onset_date: '2024-10-04'
  severity: Life-threatening
  outcome: Recovering
  intervention_required: true
  intervention_details: Prescribed high and advised life.
- symptom_name: Headache
  onset_date: '2024-10-04'
  severity: Moderate
  outcome: Not Recovered
  intervention_required: true
  intervention_details: Prescribed morning and advised approach.
causality_assessment:
  assessment_conclusion: Probable
  dechallenge_rechallenge: Rechallenge not performed
  naranjo_score: 6
reporting_facility: Adams, Harris and White Medical Center
reporter_type: Pharmacist
notes: Also ever during factor start necessary. Mean expect suffer call certain pressure.
  For surface say sound finish where bring.
