<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2025-111
Date of Submission: 2025-03-14

This report was submitted by a Patient from Mitchell, Mann and Kelley Medical Center concerning patient ANON-PX-4278. The subject is a 55-year-old other with a significant medical history including seasonal allergies, asthma. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Warfarin (Anticoagulant) administered via the Intravenous route at a dosage of 246mg, initiated on 2024-12-30 for Thromboembolism prevention and discontinued on 2025-03-06.

On approximately 2025-02-28, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Nausea, Angioedema, Headache. The Nausea was classified as Mild in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Unknown'. The Angioedema was classified as Life-threatening in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovering'. The Headache was classified as Mild in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Not Recovered'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Rechallenge not performed'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Modern later specific something. Perhaps large test sport range or because.</data>
report_id: ADR-2025-111
report_date: '2025-03-14'
patient_details:
  patient_id: ANON-PX-4278
  gender: Other
  relevant_history:
  - seasonal allergies
  - asthma
  age_at_reaction: 55
suspected_drugs:
- drug_name: Warfarin
  dosage: 246mg
  route_of_administration: Intravenous
  start_date: '2024-12-30'
  indication_for_use: Thromboembolism prevention
  drug_class: Anticoagulant
  end_date: '2025-03-06'
adverse_reactions:
- symptom_name: Nausea
  onset_date: '2025-02-28'
  severity: Mild
  outcome: Unknown
  intervention_required: false
- symptom_name: Angioedema
  onset_date: '2025-02-28'
  severity: Life-threatening
  outcome: Recovering
  intervention_required: false
- symptom_name: Headache
  onset_date: '2025-02-28'
  severity: Mild
  outcome: Not Recovered
  intervention_required: false
causality_assessment:
  assessment_conclusion: Probable
  dechallenge_rechallenge: Rechallenge not performed
reporting_facility: Mitchell, Mann and Kelley Medical Center
reporter_type: Patient
notes: Modern later specific something. Perhaps large test sport range or because.
