<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2024-825
Date of Submission: 2024-10-03

This report was submitted by a Patient from Walton LLC Medical Center concerning patient ANON-PX-1091. The subject is an adult other with a significant medical history including type 2 diabetes, atrial fibrillation, anxiety. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Levothyroxine (Thyroid hormone) administered via the Oral route at a dosage of 110mg, initiated on 2024-09-08 for Hypothyroidism and discontinued on 2024-09-17.

On approximately 2024-09-12, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Nausea, Maculopapular Rash, Pruritus, Hepatotoxicity, Headache. The Nausea was classified as Mild in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovering'. The Maculopapular Rash was classified as Mild in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovered'. The Pruritus was classified as Mild in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Unknown'. The Hepatotoxicity was classified as Life-threatening in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovered'. The Headache was classified as Life-threatening in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Unknown'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. A Naranjo score of 5 was calculated, The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Rechallenge not performed'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Several summer appear arrive. Concern top police service again form. People form image use sea ten deep.</data>
report_id: ADR-2024-825
report_date: '2024-10-03'
patient_details:
  patient_id: ANON-PX-1091
  gender: Other
  relevant_history:
  - type 2 diabetes
  - atrial fibrillation
  - anxiety
suspected_drugs:
- drug_name: Levothyroxine
  dosage: 110mg
  route_of_administration: Oral
  start_date: '2024-09-08'
  indication_for_use: Hypothyroidism
  drug_class: Thyroid hormone
  end_date: '2024-09-17'
adverse_reactions:
- symptom_name: Nausea
  onset_date: '2024-09-12'
  severity: Mild
  outcome: Recovering
  intervention_required: false
- symptom_name: Maculopapular Rash
  onset_date: '2024-09-12'
  severity: Mild
  outcome: Recovered
  intervention_required: false
- symptom_name: Pruritus
  onset_date: '2024-09-12'
  severity: Mild
  outcome: Unknown
  intervention_required: false
- symptom_name: Hepatotoxicity
  onset_date: '2024-09-12'
  severity: Life-threatening
  outcome: Recovered
  intervention_required: false
- symptom_name: Headache
  onset_date: '2024-09-12'
  severity: Life-threatening
  outcome: Unknown
  intervention_required: false
causality_assessment:
  assessment_conclusion: Probable
  dechallenge_rechallenge: Rechallenge not performed
  naranjo_score: 5
reporting_facility: Walton LLC Medical Center
reporter_type: Patient
notes: Several summer appear arrive. Concern top police service again form. People
  form image use sea ten deep.
