<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2025-755
Date of Submission: 2025-07-15

This report was submitted by a Pharmacist from Smith-Swanson Medical Center concerning patient ANON-PX-9326. The subject is a 47-year-old other with a significant medical history including hypertension, coronary artery disease, seasonal allergies. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Ibuprofen (NSAID) administered via the Intramuscular route at a dosage of 52mg, initiated on 2025-06-28 for Pain and inflammation and discontinued on 2025-07-09.

On approximately 2025-06-29, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Maculopapular Rash, Stevens-Johnson syndrome, Dizziness, Hepatotoxicity, Anaphylaxis. The Maculopapular Rash was classified as Mild in severity. This necessitated clinical intervention. The documented action was: Prescribed leader and advised task. The current patient status regarding this symptom is 'Not Recovered'. The Stevens-Johnson syndrome was classified as Life-threatening in severity. This necessitated clinical intervention. The current patient status regarding this symptom is 'Recovering'. The Dizziness was classified as Moderate in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Unknown'. The Hepatotoxicity was classified as Life-threatening in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovering'. The Anaphylaxis was classified as Severe in severity. This necessitated clinical intervention. The documented action was: Prescribed hundred and advised attack. The current patient status regarding this symptom is 'Recovering'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. A Naranjo score of 9 was calculated, The assessment concluded the relationship was 'Highly Probable'. Dechallenge/Rechallenge status was noted as: 'Positive rechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. 

</data>
report_id: ADR-2025-755
report_date: '2025-07-15'
patient_details:
  patient_id: ANON-PX-9326
  gender: Other
  relevant_history:
  - hypertension
  - coronary artery disease
  - seasonal allergies
  age_at_reaction: 47
suspected_drugs:
- drug_name: Ibuprofen
  dosage: 52mg
  route_of_administration: Intramuscular
  start_date: '2025-06-28'
  indication_for_use: Pain and inflammation
  drug_class: NSAID
  end_date: '2025-07-09'
adverse_reactions:
- symptom_name: Maculopapular Rash
  onset_date: '2025-06-29'
  severity: Mild
  outcome: Not Recovered
  intervention_required: true
  intervention_details: Prescribed leader and advised task.
- symptom_name: Stevens-Johnson syndrome
  onset_date: '2025-06-29'
  severity: Life-threatening
  outcome: Recovering
  intervention_required: true
- symptom_name: Dizziness
  onset_date: '2025-06-29'
  severity: Moderate
  outcome: Unknown
  intervention_required: false
- symptom_name: Hepatotoxicity
  onset_date: '2025-06-29'
  severity: Life-threatening
  outcome: Recovering
  intervention_required: false
- symptom_name: Anaphylaxis
  onset_date: '2025-06-29'
  severity: Severe
  outcome: Recovering
  intervention_required: true
  intervention_details: Prescribed hundred and advised attack.
causality_assessment:
  assessment_conclusion: Highly Probable
  dechallenge_rechallenge: Positive rechallenge
  naranjo_score: 9
reporting_facility: Smith-Swanson Medical Center
reporter_type: Pharmacist
