<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2025-142
Date of Submission: 2025-02-08

This report was submitted by a Pharmacist from Perez-Evans Medical Center concerning patient ANON-PX-2491. The subject is a 48-year-old male with a significant medical history including atrial fibrillation, chronic kidney disease, hypertension. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Amoxicillin administered via the Intramuscular route at a dosage of 231mg, initiated on 2024-11-29 for Bacterial infection with the course ongoing; Gabapentin administered via the Oral route at a dosage of 69mg, initiated on 2024-11-29 for Neuropathic pain with the course ongoing.

On approximately 2024-12-29, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Diarrhea, Angioedema. The Diarrhea was classified as Severe in severity. This necessitated clinical intervention. The documented action was: Prescribed reveal and advised lot. The current patient status regarding this symptom is 'Not Recovered'. The Angioedema was classified as Moderate in severity. This necessitated clinical intervention. The documented action was: Prescribed worry and advised form. The current patient status regarding this symptom is 'Unknown'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. A Naranjo score of 10 was calculated, The assessment concluded the relationship was 'Highly Probable'. Dechallenge/Rechallenge status was noted as: 'Rechallenge not performed'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Success have read push practice. Check drive position green seek. Glass minute growth soon factor data.</data>
report_id: ADR-2025-142
report_date: '2025-02-08'
patient_details:
  patient_id: ANON-PX-2491
  gender: Male
  relevant_history:
  - atrial fibrillation
  - chronic kidney disease
  - hypertension
  age_at_reaction: 48
suspected_drugs:
- drug_name: Amoxicillin
  dosage: 231mg
  route_of_administration: Intramuscular
  start_date: '2024-11-29'
  indication_for_use: Bacterial infection
- drug_name: Gabapentin
  dosage: 69mg
  route_of_administration: Oral
  start_date: '2024-11-29'
  indication_for_use: Neuropathic pain
adverse_reactions:
- symptom_name: Diarrhea
  onset_date: '2024-12-29'
  severity: Severe
  outcome: Not Recovered
  intervention_required: true
  intervention_details: Prescribed reveal and advised lot.
- symptom_name: Angioedema
  onset_date: '2024-12-29'
  severity: Moderate
  outcome: Unknown
  intervention_required: true
  intervention_details: Prescribed worry and advised form.
causality_assessment:
  assessment_conclusion: Highly Probable
  dechallenge_rechallenge: Rechallenge not performed
  naranjo_score: 10
reporting_facility: Perez-Evans Medical Center
reporter_type: Pharmacist
notes: Success have read push practice. Check drive position green seek. Glass minute
  growth soon factor data.
