<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2024-637
Date of Submission: 2024-11-27

This report was submitted by a Patient from Walker, Smith and Hawkins Medical Center concerning patient ANON-PX-3000. The subject is a 73-year-old female with a significant medical history including coronary artery disease, asthma, hypertension. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Lisinopril (ACE inhibitor) administered via the Oral route at a dosage of 484mg, initiated on 2024-09-06 for Hypertension with the course ongoing.

On approximately 2024-11-07, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Dizziness, Diarrhea, Somnolence, Angioedema, Headache. The Dizziness was classified as Mild in severity. This necessitated clinical intervention. The current patient status regarding this symptom is 'Not Recovered'. The Diarrhea was classified as Life-threatening in severity. This necessitated clinical intervention. The documented action was: Prescribed enough and advised yes. The current patient status regarding this symptom is 'Fatal'. The Somnolence was classified as Life-threatening in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovering'. The Angioedema was classified as Moderate in severity. This necessitated clinical intervention. The documented action was: Prescribed realize and advised church. The current patient status regarding this symptom is 'Not Recovered'. The Headache was classified as Severe in severity. This necessitated clinical intervention. The documented action was: Prescribed thousand and advised with. The current patient status regarding this symptom is 'Not Recovered'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Not applicable'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Nearly recently you energy look. Strong something short top evening yet once.</data>
report_id: ADR-2024-637
report_date: '2024-11-27'
patient_details:
  patient_id: ANON-PX-3000
  gender: Female
  relevant_history:
  - coronary artery disease
  - asthma
  - hypertension
  age_at_reaction: 73
suspected_drugs:
- drug_name: Lisinopril
  dosage: 484mg
  route_of_administration: Oral
  start_date: '2024-09-06'
  indication_for_use: Hypertension
  drug_class: ACE inhibitor
adverse_reactions:
- symptom_name: Dizziness
  onset_date: '2024-11-07'
  severity: Mild
  outcome: Not Recovered
  intervention_required: true
- symptom_name: Diarrhea
  onset_date: '2024-11-07'
  severity: Life-threatening
  outcome: Fatal
  intervention_required: true
  intervention_details: Prescribed enough and advised yes.
- symptom_name: Somnolence
  onset_date: '2024-11-07'
  severity: Life-threatening
  outcome: Recovering
  intervention_required: false
- symptom_name: Angioedema
  onset_date: '2024-11-07'
  severity: Moderate
  outcome: Not Recovered
  intervention_required: true
  intervention_details: Prescribed realize and advised church.
- symptom_name: Headache
  onset_date: '2024-11-07'
  severity: Severe
  outcome: Not Recovered
  intervention_required: true
  intervention_details: Prescribed thousand and advised with.
causality_assessment:
  assessment_conclusion: Probable
  dechallenge_rechallenge: Not applicable
reporting_facility: Walker, Smith and Hawkins Medical Center
reporter_type: Patient
notes: Nearly recently you energy look. Strong something short top evening yet once.
