<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2024-117
Date of Submission: 2024-09-13

This report was submitted by a Other Healthcare Professional from Tucker, Mendez and Mitchell Medical Center concerning patient ANON-PX-6893. The subject is a 56-year-old other with a significant medical history including coronary artery disease, migraines. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Lisinopril (ACE inhibitor) administered via the Topical route at a dosage of 232mg, initiated on 2024-09-03 for Hypertension with the course ongoing; Levothyroxine (Thyroid hormone) administered via the Subcutaneous route at a dosage of 5mg, initiated on 2024-09-03 for Hypothyroidism with the course ongoing.

On approximately 2024-09-10, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Nausea, Angioedema. The Nausea was classified as Severe in severity. This necessitated clinical intervention. The documented action was: Prescribed everyone and advised air. The current patient status regarding this symptom is 'Unknown'. The Angioedema was classified as Mild in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Unknown'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. A Naranjo score of 4 was calculated, The assessment concluded the relationship was 'Possible'. Dechallenge/Rechallenge status was noted as: 'Rechallenge not performed'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Exactly last send growth half. Mr research while modern no. Firm later establish example family.</data>
report_id: ADR-2024-117
report_date: '2024-09-13'
patient_details:
  patient_id: ANON-PX-6893
  gender: Other
  relevant_history:
  - coronary artery disease
  - migraines
  age_at_reaction: 56
suspected_drugs:
- drug_name: Lisinopril
  dosage: 232mg
  route_of_administration: Topical
  start_date: '2024-09-03'
  indication_for_use: Hypertension
  drug_class: ACE inhibitor
- drug_name: Levothyroxine
  dosage: 5mg
  route_of_administration: Subcutaneous
  start_date: '2024-09-03'
  indication_for_use: Hypothyroidism
  drug_class: Thyroid hormone
adverse_reactions:
- symptom_name: Nausea
  onset_date: '2024-09-10'
  severity: Severe
  outcome: Unknown
  intervention_required: true
  intervention_details: Prescribed everyone and advised air.
- symptom_name: Angioedema
  onset_date: '2024-09-10'
  severity: Mild
  outcome: Unknown
  intervention_required: false
causality_assessment:
  assessment_conclusion: Possible
  dechallenge_rechallenge: Rechallenge not performed
  naranjo_score: 4
reporting_facility: Tucker, Mendez and Mitchell Medical Center
reporter_type: Other Healthcare Professional
notes: Exactly last send growth half. Mr research while modern no. Firm later establish
  example family.
