<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2025-111
Date of Submission: 2025-06-13

This report was submitted by a Patient from Acosta, Williams and Hill Medical Center concerning patient ANON-PX-3356. The subject is an adult female with a significant medical history including atrial fibrillation, hypertension, coronary artery disease, anxiety. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Atorvastatin (Statin) administered via the Intravenous route at a dosage of 176mg, initiated on 2025-04-17 for Hypercholesterolemia and discontinued on 2025-06-09.

On approximately 2025-06-08, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Anaphylaxis, Maculopapular Rash, Angioedema, Vomiting, Pruritus. The Anaphylaxis was classified as Severe in severity. This necessitated clinical intervention. The documented action was: Prescribed camera and advised share. The current patient status regarding this symptom is 'Fatal'. The Maculopapular Rash was classified as Mild in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Fatal'. The Angioedema was classified as Severe in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovered'. The Vomiting was classified as Life-threatening in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Unknown'. The Pruritus was classified as Life-threatening in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovered'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Positive rechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Prove thank want wide. Mrs consumer size claim garden.</data>
report_id: ADR-2025-111
report_date: '2025-06-13'
patient_details:
  patient_id: ANON-PX-3356
  gender: Female
  relevant_history:
  - atrial fibrillation
  - hypertension
  - coronary artery disease
  - anxiety
suspected_drugs:
- drug_name: Atorvastatin
  dosage: 176mg
  route_of_administration: Intravenous
  start_date: '2025-04-17'
  indication_for_use: Hypercholesterolemia
  drug_class: Statin
  end_date: '2025-06-09'
adverse_reactions:
- symptom_name: Anaphylaxis
  onset_date: '2025-06-08'
  severity: Severe
  outcome: Fatal
  intervention_required: true
  intervention_details: Prescribed camera and advised share.
- symptom_name: Maculopapular Rash
  onset_date: '2025-06-08'
  severity: Mild
  outcome: Fatal
  intervention_required: false
- symptom_name: Angioedema
  onset_date: '2025-06-08'
  severity: Severe
  outcome: Recovered
  intervention_required: false
- symptom_name: Vomiting
  onset_date: '2025-06-08'
  severity: Life-threatening
  outcome: Unknown
  intervention_required: false
- symptom_name: Pruritus
  onset_date: '2025-06-08'
  severity: Life-threatening
  outcome: Recovered
  intervention_required: false
causality_assessment:
  assessment_conclusion: Probable
  dechallenge_rechallenge: Positive rechallenge
reporting_facility: Acosta, Williams and Hill Medical Center
reporter_type: Patient
notes: Prove thank want wide. Mrs consumer size claim garden.
