<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2025-836
Date of Submission: 2025-01-23

This report was submitted by a Other Healthcare Professional from Williams Group Medical Center concerning patient ANON-PX-6940. The subject is a 64-year-old female with a significant medical history including seasonal allergies, coronary artery disease, type 2 diabetes, atrial fibrillation. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Atorvastatin (Statin) administered via the Intramuscular route at a dosage of 152mg, initiated on 2024-11-06 for Hypercholesterolemia and discontinued on 2025-01-06.

On approximately 2024-12-23, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Diarrhea, Hepatotoxicity. The Diarrhea was classified as Mild in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovered'. The Hepatotoxicity was classified as Life-threatening in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Unknown'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. A Naranjo score of 4 was calculated, The assessment concluded the relationship was 'Possible'. Dechallenge/Rechallenge status was noted as: 'Positive rechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Simply himself trip who tend name treat moment. Enter yes meeting exactly try start the. Western admit fight when sing.</data>
report_id: ADR-2025-836
report_date: '2025-01-23'
patient_details:
  patient_id: ANON-PX-6940
  gender: Female
  relevant_history:
  - seasonal allergies
  - coronary artery disease
  - type 2 diabetes
  - atrial fibrillation
  age_at_reaction: 64
suspected_drugs:
- drug_name: Atorvastatin
  dosage: 152mg
  route_of_administration: Intramuscular
  start_date: '2024-11-06'
  indication_for_use: Hypercholesterolemia
  drug_class: Statin
  end_date: '2025-01-06'
adverse_reactions:
- symptom_name: Diarrhea
  onset_date: '2024-12-23'
  severity: Mild
  outcome: Recovered
  intervention_required: false
- symptom_name: Hepatotoxicity
  onset_date: '2024-12-23'
  severity: Life-threatening
  outcome: Unknown
  intervention_required: false
causality_assessment:
  assessment_conclusion: Possible
  dechallenge_rechallenge: Positive rechallenge
  naranjo_score: 4
reporting_facility: Williams Group Medical Center
reporter_type: Other Healthcare Professional
notes: Simply himself trip who tend name treat moment. Enter yes meeting exactly try
  start the. Western admit fight when sing.
