<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2025-947
Date of Submission: 2025-02-11

This report was submitted by a Patient from Townsend and Sons Medical Center concerning patient ANON-PX-5469. The subject is an adult other with a significant medical history including coronary artery disease, type 2 diabetes. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Warfarin (Anticoagulant) administered via the Intravenous route at a dosage of 476mg, initiated on 2024-12-30 for Thromboembolism prevention and discontinued on 2025-02-07.

On approximately 2025-02-06, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Headache, Dizziness, Vomiting, Hepatotoxicity. The Headache was classified as Severe in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovered'. The Dizziness was classified as Moderate in severity. This necessitated clinical intervention. The current patient status regarding this symptom is 'Not Recovered'. The Vomiting was classified as Severe in severity. This necessitated clinical intervention. The documented action was: Prescribed recent and advised like. The current patient status regarding this symptom is 'Recovering'. The Hepatotoxicity was classified as Severe in severity. This necessitated clinical intervention. The current patient status regarding this symptom is 'Not Recovered'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Rechallenge not performed'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: News natural hour.</data>
report_id: ADR-2025-947
report_date: '2025-02-11'
patient_details:
  patient_id: ANON-PX-5469
  gender: Other
  relevant_history:
  - coronary artery disease
  - type 2 diabetes
suspected_drugs:
- drug_name: Warfarin
  dosage: 476mg
  route_of_administration: Intravenous
  start_date: '2024-12-30'
  indication_for_use: Thromboembolism prevention
  drug_class: Anticoagulant
  end_date: '2025-02-07'
adverse_reactions:
- symptom_name: Headache
  onset_date: '2025-02-06'
  severity: Severe
  outcome: Recovered
  intervention_required: false
- symptom_name: Dizziness
  onset_date: '2025-02-06'
  severity: Moderate
  outcome: Not Recovered
  intervention_required: true
- symptom_name: Vomiting
  onset_date: '2025-02-06'
  severity: Severe
  outcome: Recovering
  intervention_required: true
  intervention_details: Prescribed recent and advised like.
- symptom_name: Hepatotoxicity
  onset_date: '2025-02-06'
  severity: Severe
  outcome: Not Recovered
  intervention_required: true
causality_assessment:
  assessment_conclusion: Probable
  dechallenge_rechallenge: Rechallenge not performed
reporting_facility: Townsend and Sons Medical Center
reporter_type: Patient
notes: News natural hour.
