<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2024-264
Date of Submission: 2024-12-05

This report was submitted by a Other Healthcare Professional from Martinez, Garcia and Garza Medical Center concerning patient ANON-PX-4074. The subject is a 39-year-old other with a significant medical history including osteoarthritis, asthma. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Sertraline (SSRI) administered via the Subcutaneous route at a dosage of 353mg, initiated on 2024-10-23 for Major depressive disorder and discontinued on 2024-11-26.

On approximately 2024-11-01, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Hepatotoxicity, Angioedema. The Hepatotoxicity was classified as Mild in severity. This necessitated clinical intervention. The current patient status regarding this symptom is 'Unknown'. The Angioedema was classified as Life-threatening in severity. This necessitated clinical intervention. The current patient status regarding this symptom is 'Unknown'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. A Naranjo score of 7 was calculated, The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Positive dechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Goal say protect energy. Call decade find challenge. After once who authority oil begin listen.</data>
report_id: ADR-2024-264
report_date: '2024-12-05'
patient_details:
  patient_id: ANON-PX-4074
  gender: Other
  relevant_history:
  - osteoarthritis
  - asthma
  age_at_reaction: 39
suspected_drugs:
- drug_name: Sertraline
  dosage: 353mg
  route_of_administration: Subcutaneous
  start_date: '2024-10-23'
  indication_for_use: Major depressive disorder
  drug_class: SSRI
  end_date: '2024-11-26'
adverse_reactions:
- symptom_name: Hepatotoxicity
  onset_date: '2024-11-01'
  severity: Mild
  outcome: Unknown
  intervention_required: true
- symptom_name: Angioedema
  onset_date: '2024-11-01'
  severity: Life-threatening
  outcome: Unknown
  intervention_required: true
causality_assessment:
  assessment_conclusion: Probable
  dechallenge_rechallenge: Positive dechallenge
  naranjo_score: 7
reporting_facility: Martinez, Garcia and Garza Medical Center
reporter_type: Other Healthcare Professional
notes: Goal say protect energy. Call decade find challenge. After once who authority
  oil begin listen.
