<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2024-290
Date of Submission: 2024-11-08

This report was submitted by a Patient from Stewart-Rodriguez Medical Center concerning patient ANON-PX-5962. The subject is a 31-year-old female with a significant medical history including coronary artery disease, seasonal allergies, chronic kidney disease. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Sertraline (SSRI) administered via the Intravenous route at a dosage of 380mg, initiated on 2024-08-15 for Major depressive disorder and discontinued on 2024-11-01.

On approximately 2024-10-30, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Diarrhea, Stevens-Johnson syndrome, Anaphylaxis, Hepatotoxicity. The Diarrhea was classified as Mild in severity. This necessitated clinical intervention. The documented action was: Prescribed total and advised despite. The current patient status regarding this symptom is 'Recovering'. The Stevens-Johnson syndrome was classified as Life-threatening in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovered'. The Anaphylaxis was classified as Life-threatening in severity. This necessitated clinical intervention. The current patient status regarding this symptom is 'Recovered'. The Hepatotoxicity was classified as Moderate in severity. This necessitated clinical intervention. The documented action was: Prescribed parent and advised doctor. The current patient status regarding this symptom is 'Not Recovered'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. A Naranjo score of 4 was calculated, The assessment concluded the relationship was 'Possible'. Dechallenge/Rechallenge status was noted as: 'Positive rechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: May sell hotel military successful begin. Theory market buy lay artist than back. Inside crime fly technology over too head.</data>
report_id: ADR-2024-290
report_date: '2024-11-08'
patient_details:
  patient_id: ANON-PX-5962
  gender: Female
  relevant_history:
  - coronary artery disease
  - seasonal allergies
  - chronic kidney disease
  age_at_reaction: 31
suspected_drugs:
- drug_name: Sertraline
  dosage: 380mg
  route_of_administration: Intravenous
  start_date: '2024-08-15'
  indication_for_use: Major depressive disorder
  drug_class: SSRI
  end_date: '2024-11-01'
adverse_reactions:
- symptom_name: Diarrhea
  onset_date: '2024-10-30'
  severity: Mild
  outcome: Recovering
  intervention_required: true
  intervention_details: Prescribed total and advised despite.
- symptom_name: Stevens-Johnson syndrome
  onset_date: '2024-10-30'
  severity: Life-threatening
  outcome: Recovered
  intervention_required: false
- symptom_name: Anaphylaxis
  onset_date: '2024-10-30'
  severity: Life-threatening
  outcome: Recovered
  intervention_required: true
- symptom_name: Hepatotoxicity
  onset_date: '2024-10-30'
  severity: Moderate
  outcome: Not Recovered
  intervention_required: true
  intervention_details: Prescribed parent and advised doctor.
causality_assessment:
  assessment_conclusion: Possible
  dechallenge_rechallenge: Positive rechallenge
  naranjo_score: 4
reporting_facility: Stewart-Rodriguez Medical Center
reporter_type: Patient
notes: May sell hotel military successful begin. Theory market buy lay artist than
  back. Inside crime fly technology over too head.
