<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2025-902
Date of Submission: 2025-02-18

This report was submitted by a Other Healthcare Professional from Campbell, Rios and Parker Medical Center concerning patient ANON-PX-5608. The subject is a 55-year-old female with a significant medical history including seasonal allergies, osteoarthritis, chronic kidney disease. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Lisinopril (ACE inhibitor) administered via the Oral route at a dosage of 185mg, initiated on 2025-01-09 for Hypertension and discontinued on 2025-02-06; Amoxicillin (Penicillin antibiotic) administered via the Oral route at a dosage of 60mg, initiated on 2025-01-09 for Bacterial infection and discontinued on 2025-02-06.

On approximately 2025-02-06, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Nausea, Anaphylaxis, Hepatotoxicity, Somnolence. The Nausea was classified as Life-threatening in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovered'. The Anaphylaxis was classified as Severe in severity. This necessitated clinical intervention. The documented action was: Prescribed thousand and advised tend. The current patient status regarding this symptom is 'Recovering'. The Hepatotoxicity was classified as Severe in severity. This necessitated clinical intervention. The documented action was: Prescribed cold and advised plant. The current patient status regarding this symptom is 'Fatal'. The Somnolence was classified as Moderate in severity. This necessitated clinical intervention. The current patient status regarding this symptom is 'Recovered'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. A Naranjo score of 7 was calculated, The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Positive rechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Have matter late news first within over.</data>
report_id: ADR-2025-902
report_date: '2025-02-18'
patient_details:
  patient_id: ANON-PX-5608
  gender: Female
  relevant_history:
  - seasonal allergies
  - osteoarthritis
  - chronic kidney disease
  age_at_reaction: 55
suspected_drugs:
- drug_name: Lisinopril
  dosage: 185mg
  route_of_administration: Oral
  start_date: '2025-01-09'
  indication_for_use: Hypertension
  drug_class: ACE inhibitor
  end_date: '2025-02-06'
- drug_name: Amoxicillin
  dosage: 60mg
  route_of_administration: Oral
  start_date: '2025-01-09'
  indication_for_use: Bacterial infection
  drug_class: Penicillin antibiotic
  end_date: '2025-02-06'
adverse_reactions:
- symptom_name: Nausea
  onset_date: '2025-02-06'
  severity: Life-threatening
  outcome: Recovered
  intervention_required: false
- symptom_name: Anaphylaxis
  onset_date: '2025-02-06'
  severity: Severe
  outcome: Recovering
  intervention_required: true
  intervention_details: Prescribed thousand and advised tend.
- symptom_name: Hepatotoxicity
  onset_date: '2025-02-06'
  severity: Severe
  outcome: Fatal
  intervention_required: true
  intervention_details: Prescribed cold and advised plant.
- symptom_name: Somnolence
  onset_date: '2025-02-06'
  severity: Moderate
  outcome: Recovered
  intervention_required: true
causality_assessment:
  assessment_conclusion: Probable
  dechallenge_rechallenge: Positive rechallenge
  naranjo_score: 7
reporting_facility: Campbell, Rios and Parker Medical Center
reporter_type: Other Healthcare Professional
notes: Have matter late news first within over.
