<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2024-798
Date of Submission: 2024-12-12

This report was submitted by a Pharmacist from Ryan PLC Medical Center concerning patient ANON-PX-1265. The subject is a 54-year-old female with a significant medical history including osteoarthritis, chronic kidney disease. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Ibuprofen (NSAID) administered via the Intramuscular route at a dosage of 17mg, initiated on 2024-11-15 for Pain and inflammation and discontinued on 2024-12-05.

On approximately 2024-11-23, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Vomiting, Diarrhea, Stevens-Johnson syndrome, Nausea, Dizziness. The Vomiting was classified as Severe in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovering'. The Diarrhea was classified as Severe in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Unknown'. The Stevens-Johnson syndrome was classified as Life-threatening in severity. This necessitated clinical intervention. The documented action was: Prescribed glass and advised audience. The current patient status regarding this symptom is 'Recovered'. The Nausea was classified as Moderate in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Unknown'. The Dizziness was classified as Mild in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovering'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Positive rechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Subject learn market center high. Compare board involve. Production five article team.</data>
report_id: ADR-2024-798
report_date: '2024-12-12'
patient_details:
  patient_id: ANON-PX-1265
  gender: Female
  relevant_history:
  - osteoarthritis
  - chronic kidney disease
  age_at_reaction: 54
suspected_drugs:
- drug_name: Ibuprofen
  dosage: 17mg
  route_of_administration: Intramuscular
  start_date: '2024-11-15'
  indication_for_use: Pain and inflammation
  drug_class: NSAID
  end_date: '2024-12-05'
adverse_reactions:
- symptom_name: Vomiting
  onset_date: '2024-11-23'
  severity: Severe
  outcome: Recovering
  intervention_required: false
- symptom_name: Diarrhea
  onset_date: '2024-11-23'
  severity: Severe
  outcome: Unknown
  intervention_required: false
- symptom_name: Stevens-Johnson syndrome
  onset_date: '2024-11-23'
  severity: Life-threatening
  outcome: Recovered
  intervention_required: true
  intervention_details: Prescribed glass and advised audience.
- symptom_name: Nausea
  onset_date: '2024-11-23'
  severity: Moderate
  outcome: Unknown
  intervention_required: false
- symptom_name: Dizziness
  onset_date: '2024-11-23'
  severity: Mild
  outcome: Recovering
  intervention_required: false
causality_assessment:
  assessment_conclusion: Probable
  dechallenge_rechallenge: Positive rechallenge
reporting_facility: Ryan PLC Medical Center
reporter_type: Pharmacist
notes: Subject learn market center high. Compare board involve. Production five article
  team.
