<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2025-100
Date of Submission: 2025-04-12

This report was submitted by a Nurse from Mejia, Carpenter and Browning Medical Center concerning patient ANON-PX-3070. The subject is a 37-year-old male with a significant medical history including osteoarthritis, migraines. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Ibuprofen (NSAID) administered via the Intravenous route at a dosage of 96mg, initiated on 2025-01-28 for Pain and inflammation with the course ongoing.

On approximately 2025-03-31, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Somnolence, Pruritus, Diarrhea. The Somnolence was classified as Mild in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Fatal'. The Pruritus was classified as Severe in severity. This necessitated clinical intervention. The documented action was: Prescribed mean and advised relationship. The current patient status regarding this symptom is 'Recovering'. The Diarrhea was classified as Life-threatening in severity. This necessitated clinical intervention. The documented action was: Prescribed now and advised bad. The current patient status regarding this symptom is 'Unknown'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. A Naranjo score of 8 was calculated, The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Not applicable'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Art idea professional individual role same. Book author son.</data>
report_id: ADR-2025-100
report_date: '2025-04-12'
patient_details:
  patient_id: ANON-PX-3070
  gender: Male
  relevant_history:
  - osteoarthritis
  - migraines
  age_at_reaction: 37
suspected_drugs:
- drug_name: Ibuprofen
  dosage: 96mg
  route_of_administration: Intravenous
  start_date: '2025-01-28'
  indication_for_use: Pain and inflammation
  drug_class: NSAID
adverse_reactions:
- symptom_name: Somnolence
  onset_date: '2025-03-31'
  severity: Mild
  outcome: Fatal
  intervention_required: false
- symptom_name: Pruritus
  onset_date: '2025-03-31'
  severity: Severe
  outcome: Recovering
  intervention_required: true
  intervention_details: Prescribed mean and advised relationship.
- symptom_name: Diarrhea
  onset_date: '2025-03-31'
  severity: Life-threatening
  outcome: Unknown
  intervention_required: true
  intervention_details: Prescribed now and advised bad.
causality_assessment:
  assessment_conclusion: Probable
  dechallenge_rechallenge: Not applicable
  naranjo_score: 8
reporting_facility: Mejia, Carpenter and Browning Medical Center
reporter_type: Nurse
notes: Art idea professional individual role same. Book author son.
