<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2024-315
Date of Submission: 2024-12-07

This report was submitted by a Other Healthcare Professional from Douglas-Jones Medical Center concerning patient ANON-PX-2112. The subject is an adult other with a significant medical history including atrial fibrillation, coronary artery disease, chronic kidney disease, migraines. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Omeprazole (Proton-pump inhibitor) administered via the Intramuscular route at a dosage of 288mg, initiated on 2024-10-18 for Gastroesophageal reflux disease with the course ongoing; Atorvastatin (Statin) administered via the Intramuscular route at a dosage of 283mg, initiated on 2024-10-18 for Hypercholesterolemia with the course ongoing.

On approximately 2024-11-20, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Dizziness, Stevens-Johnson syndrome, Pruritus. The Dizziness was classified as Moderate in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Unknown'. The Stevens-Johnson syndrome was classified as Moderate in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Unknown'. The Pruritus was classified as Life-threatening in severity. This necessitated clinical intervention. The documented action was: Prescribed understand and advised Republican. The current patient status regarding this symptom is 'Fatal'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. A Naranjo score of 10 was calculated, The assessment concluded the relationship was 'Highly Probable'. Dechallenge/Rechallenge status was noted as: 'Negative dechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Clear never six move. Performance pretty care fund recently career paper mother.</data>
report_id: ADR-2024-315
report_date: '2024-12-07'
patient_details:
  patient_id: ANON-PX-2112
  gender: Other
  relevant_history:
  - atrial fibrillation
  - coronary artery disease
  - chronic kidney disease
  - migraines
suspected_drugs:
- drug_name: Omeprazole
  dosage: 288mg
  route_of_administration: Intramuscular
  start_date: '2024-10-18'
  indication_for_use: Gastroesophageal reflux disease
  drug_class: Proton-pump inhibitor
- drug_name: Atorvastatin
  dosage: 283mg
  route_of_administration: Intramuscular
  start_date: '2024-10-18'
  indication_for_use: Hypercholesterolemia
  drug_class: Statin
adverse_reactions:
- symptom_name: Dizziness
  onset_date: '2024-11-20'
  severity: Moderate
  outcome: Unknown
  intervention_required: false
- symptom_name: Stevens-Johnson syndrome
  onset_date: '2024-11-20'
  severity: Moderate
  outcome: Unknown
  intervention_required: false
- symptom_name: Pruritus
  onset_date: '2024-11-20'
  severity: Life-threatening
  outcome: Fatal
  intervention_required: true
  intervention_details: Prescribed understand and advised Republican.
causality_assessment:
  assessment_conclusion: Highly Probable
  dechallenge_rechallenge: Negative dechallenge
  naranjo_score: 10
reporting_facility: Douglas-Jones Medical Center
reporter_type: Other Healthcare Professional
notes: Clear never six move. Performance pretty care fund recently career paper mother.
