<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2024-866
Date of Submission: 2024-09-06

This report was submitted by a Other Healthcare Professional from Cunningham, Taylor and Garcia Medical Center concerning patient ANON-PX-5258. The subject is a 86-year-old male with a significant medical history including migraines, anxiety. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Gabapentin (Anticonvulsant) administered via the Intramuscular route at a dosage of 385mg, initiated on 2024-07-27 for Neuropathic pain and discontinued on 2024-08-31; Metformin (Biguanide) administered via the Intramuscular route at a dosage of 127mg, initiated on 2024-07-27 for Type 2 diabetes and discontinued on 2024-08-31.

On approximately 2024-08-15, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Somnolence, Dizziness, Diarrhea, Angioedema. The Somnolence was classified as Life-threatening in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovered'. The Dizziness was classified as Severe in severity. This necessitated clinical intervention. The documented action was: Prescribed or and advised lay. The current patient status regarding this symptom is 'Not Recovered'. The Diarrhea was classified as Severe in severity. This necessitated clinical intervention. The documented action was: Prescribed design and advised tonight. The current patient status regarding this symptom is 'Unknown'. The Angioedema was classified as Life-threatening in severity. This necessitated clinical intervention. The documented action was: Prescribed night and advised sing. The current patient status regarding this symptom is 'Not Recovered'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. A Naranjo score of 5 was calculated, The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Negative dechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. 

</data>
report_id: ADR-2024-866
report_date: '2024-09-06'
patient_details:
  patient_id: ANON-PX-5258
  gender: Male
  relevant_history:
  - migraines
  - anxiety
  age_at_reaction: 86
suspected_drugs:
- drug_name: Gabapentin
  dosage: 385mg
  route_of_administration: Intramuscular
  start_date: '2024-07-27'
  indication_for_use: Neuropathic pain
  drug_class: Anticonvulsant
  end_date: '2024-08-31'
- drug_name: Metformin
  dosage: 127mg
  route_of_administration: Intramuscular
  start_date: '2024-07-27'
  indication_for_use: Type 2 diabetes
  drug_class: Biguanide
  end_date: '2024-08-31'
adverse_reactions:
- symptom_name: Somnolence
  onset_date: '2024-08-15'
  severity: Life-threatening
  outcome: Recovered
  intervention_required: false
- symptom_name: Dizziness
  onset_date: '2024-08-15'
  severity: Severe
  outcome: Not Recovered
  intervention_required: true
  intervention_details: Prescribed or and advised lay.
- symptom_name: Diarrhea
  onset_date: '2024-08-15'
  severity: Severe
  outcome: Unknown
  intervention_required: true
  intervention_details: Prescribed design and advised tonight.
- symptom_name: Angioedema
  onset_date: '2024-08-15'
  severity: Life-threatening
  outcome: Not Recovered
  intervention_required: true
  intervention_details: Prescribed night and advised sing.
causality_assessment:
  assessment_conclusion: Probable
  dechallenge_rechallenge: Negative dechallenge
  naranjo_score: 5
reporting_facility: Cunningham, Taylor and Garcia Medical Center
reporter_type: Other Healthcare Professional
