<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2024-552
Date of Submission: 2024-12-01

This report was submitted by a Other Healthcare Professional from Sims-Luna Medical Center concerning patient ANON-PX-6307. The subject is a 79-year-old male with a significant medical history including asthma, anxiety, atrial fibrillation. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Amoxicillin (Penicillin antibiotic) administered via the Topical route at a dosage of 348mg, initiated on 2024-10-01 for Bacterial infection and discontinued on 2024-11-30; Atorvastatin (Statin) administered via the Subcutaneous route at a dosage of 146mg, initiated on 2024-10-01 for Hypercholesterolemia and discontinued on 2024-11-30.

On approximately 2024-11-28, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Stevens-Johnson syndrome, Dizziness, Angioedema. The Stevens-Johnson syndrome was classified as Moderate in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovered'. The Dizziness was classified as Mild in severity. This necessitated clinical intervention. The current patient status regarding this symptom is 'Fatal'. The Angioedema was classified as Severe in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovering'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. A Naranjo score of 2 was calculated, The assessment concluded the relationship was 'Possible'. Dechallenge/Rechallenge status was noted as: 'Not applicable'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Public usually example describe direction. Police opportunity themselves close black exist peace doctor. Often list also there focus event bad.</data>
report_id: ADR-2024-552
report_date: '2024-12-01'
patient_details:
  patient_id: ANON-PX-6307
  gender: Male
  relevant_history:
  - asthma
  - anxiety
  - atrial fibrillation
  age_at_reaction: 79
suspected_drugs:
- drug_name: Amoxicillin
  dosage: 348mg
  route_of_administration: Topical
  start_date: '2024-10-01'
  indication_for_use: Bacterial infection
  drug_class: Penicillin antibiotic
  end_date: '2024-11-30'
- drug_name: Atorvastatin
  dosage: 146mg
  route_of_administration: Subcutaneous
  start_date: '2024-10-01'
  indication_for_use: Hypercholesterolemia
  drug_class: Statin
  end_date: '2024-11-30'
adverse_reactions:
- symptom_name: Stevens-Johnson syndrome
  onset_date: '2024-11-28'
  severity: Moderate
  outcome: Recovered
  intervention_required: false
- symptom_name: Dizziness
  onset_date: '2024-11-28'
  severity: Mild
  outcome: Fatal
  intervention_required: true
- symptom_name: Angioedema
  onset_date: '2024-11-28'
  severity: Severe
  outcome: Recovering
  intervention_required: false
causality_assessment:
  assessment_conclusion: Possible
  dechallenge_rechallenge: Not applicable
  naranjo_score: 2
reporting_facility: Sims-Luna Medical Center
reporter_type: Other Healthcare Professional
notes: Public usually example describe direction. Police opportunity themselves close
  black exist peace doctor. Often list also there focus event bad.
