<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2025-512
Date of Submission: 2025-07-07

This report was submitted by a Patient from Trujillo, Drake and Edwards Medical Center concerning patient ANON-PX-1228. The subject is a 36-year-old other with a significant medical history including coronary artery disease, chronic kidney disease. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Lisinopril administered via the Subcutaneous route at a dosage of 389mg, initiated on 2025-04-19 for Hypertension with the course ongoing; Omeprazole administered via the Intramuscular route at a dosage of 184mg, initiated on 2025-04-19 for Gastroesophageal reflux disease with the course ongoing.

On approximately 2025-05-15, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Pruritus, Somnolence, Diarrhea. The Pruritus was classified as Life-threatening in severity. This necessitated clinical intervention. The current patient status regarding this symptom is 'Not Recovered'. The Somnolence was classified as Moderate in severity. This necessitated clinical intervention. The documented action was: Prescribed too and advised her. The current patient status regarding this symptom is 'Fatal'. The Diarrhea was classified as Moderate in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Not Recovered'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Positive rechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Trade claim left however doctor whose follow goal. Tax job hotel perhaps good not pattern.</data>
report_id: ADR-2025-512
report_date: '2025-07-07'
patient_details:
  patient_id: ANON-PX-1228
  gender: Other
  relevant_history:
  - coronary artery disease
  - chronic kidney disease
  age_at_reaction: 36
suspected_drugs:
- drug_name: Lisinopril
  dosage: 389mg
  route_of_administration: Subcutaneous
  start_date: '2025-04-19'
  indication_for_use: Hypertension
- drug_name: Omeprazole
  dosage: 184mg
  route_of_administration: Intramuscular
  start_date: '2025-04-19'
  indication_for_use: Gastroesophageal reflux disease
adverse_reactions:
- symptom_name: Pruritus
  onset_date: '2025-05-15'
  severity: Life-threatening
  outcome: Not Recovered
  intervention_required: true
- symptom_name: Somnolence
  onset_date: '2025-05-15'
  severity: Moderate
  outcome: Fatal
  intervention_required: true
  intervention_details: Prescribed too and advised her.
- symptom_name: Diarrhea
  onset_date: '2025-05-15'
  severity: Moderate
  outcome: Not Recovered
  intervention_required: false
causality_assessment:
  assessment_conclusion: Probable
  dechallenge_rechallenge: Positive rechallenge
reporting_facility: Trujillo, Drake and Edwards Medical Center
reporter_type: Patient
notes: Trade claim left however doctor whose follow goal. Tax job hotel perhaps good
  not pattern.
