<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2025-251
Date of Submission: 2025-05-31

This report was submitted by a Patient from Brown LLC Medical Center concerning patient ANON-PX-6286. The subject is an adult female with a significant medical history including type 2 diabetes, chronic kidney disease. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Warfarin (Anticoagulant) administered via the Subcutaneous route at a dosage of 355mg, initiated on 2025-04-07 for Thromboembolism prevention with the course ongoing; Amoxicillin (Penicillin antibiotic) administered via the Subcutaneous route at a dosage of 68mg, initiated on 2025-04-07 for Bacterial infection with the course ongoing.

On approximately 2025-05-19, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Angioedema, Dizziness. The Angioedema was classified as Severe in severity. This necessitated clinical intervention. The current patient status regarding this symptom is 'Not Recovered'. The Dizziness was classified as Life-threatening in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovered'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Not applicable'. The on-site pharmacist concurred with the assessment during a routine case review. 

</data>
report_id: ADR-2025-251
report_date: '2025-05-31'
patient_details:
  patient_id: ANON-PX-6286
  gender: Female
  relevant_history:
  - type 2 diabetes
  - chronic kidney disease
suspected_drugs:
- drug_name: Warfarin
  dosage: 355mg
  route_of_administration: Subcutaneous
  start_date: '2025-04-07'
  indication_for_use: Thromboembolism prevention
  drug_class: Anticoagulant
- drug_name: Amoxicillin
  dosage: 68mg
  route_of_administration: Subcutaneous
  start_date: '2025-04-07'
  indication_for_use: Bacterial infection
  drug_class: Penicillin antibiotic
adverse_reactions:
- symptom_name: Angioedema
  onset_date: '2025-05-19'
  severity: Severe
  outcome: Not Recovered
  intervention_required: true
- symptom_name: Dizziness
  onset_date: '2025-05-19'
  severity: Life-threatening
  outcome: Recovered
  intervention_required: false
causality_assessment:
  assessment_conclusion: Probable
  dechallenge_rechallenge: Not applicable
reporting_facility: Brown LLC Medical Center
reporter_type: Patient
