<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2025-446
Date of Submission: 2025-07-19

This report was submitted by a Physician from Wilson Ltd Medical Center concerning patient ANON-PX-6260. The subject is an adult female with a significant medical history including hypertension, seasonal allergies, osteoarthritis. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Gabapentin (Anticonvulsant) administered via the Intravenous route at a dosage of 272mg, initiated on 2025-05-27 for Neuropathic pain with the course ongoing; Omeprazole (Proton-pump inhibitor) administered via the Intravenous route at a dosage of 255mg, initiated on 2025-05-27 for Gastroesophageal reflux disease with the course ongoing.

On approximately 2025-07-04, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Anaphylaxis, Stevens-Johnson syndrome, Pruritus, Vomiting. The Anaphylaxis was classified as Moderate in severity. This necessitated clinical intervention. The current patient status regarding this symptom is 'Unknown'. The Stevens-Johnson syndrome was classified as Mild in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Fatal'. The Pruritus was classified as Moderate in severity. This necessitated clinical intervention. The documented action was: Prescribed author and advised camera. The current patient status regarding this symptom is 'Recovered'. The Vomiting was classified as Moderate in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovered'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Rechallenge not performed'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Already nature break memory figure. Different off gas beyond.</data>
report_id: ADR-2025-446
report_date: '2025-07-19'
patient_details:
  patient_id: ANON-PX-6260
  gender: Female
  relevant_history:
  - hypertension
  - seasonal allergies
  - osteoarthritis
suspected_drugs:
- drug_name: Gabapentin
  dosage: 272mg
  route_of_administration: Intravenous
  start_date: '2025-05-27'
  indication_for_use: Neuropathic pain
  drug_class: Anticonvulsant
- drug_name: Omeprazole
  dosage: 255mg
  route_of_administration: Intravenous
  start_date: '2025-05-27'
  indication_for_use: Gastroesophageal reflux disease
  drug_class: Proton-pump inhibitor
adverse_reactions:
- symptom_name: Anaphylaxis
  onset_date: '2025-07-04'
  severity: Moderate
  outcome: Unknown
  intervention_required: true
- symptom_name: Stevens-Johnson syndrome
  onset_date: '2025-07-04'
  severity: Mild
  outcome: Fatal
  intervention_required: false
- symptom_name: Pruritus
  onset_date: '2025-07-04'
  severity: Moderate
  outcome: Recovered
  intervention_required: true
  intervention_details: Prescribed author and advised camera.
- symptom_name: Vomiting
  onset_date: '2025-07-04'
  severity: Moderate
  outcome: Recovered
  intervention_required: false
causality_assessment:
  assessment_conclusion: Probable
  dechallenge_rechallenge: Rechallenge not performed
reporting_facility: Wilson Ltd Medical Center
reporter_type: Physician
notes: Already nature break memory figure. Different off gas beyond.
