<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2025-338
Date of Submission: 2025-02-10

This report was submitted by a Nurse from Lane, Mckinney and Riddle Medical Center concerning patient ANON-PX-6561. The subject is a 41-year-old other with a significant medical history including atrial fibrillation, type 2 diabetes, coronary artery disease, hypertension. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Amoxicillin (Penicillin antibiotic) administered via the Oral route at a dosage of 377mg, initiated on 2025-01-13 for Bacterial infection with the course ongoing.

On approximately 2025-01-20, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Anaphylaxis, Nausea, Headache, Diarrhea, Pruritus. The Anaphylaxis was classified as Mild in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovering'. The Nausea was classified as Mild in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovering'. The Headache was classified as Mild in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovering'. The Diarrhea was classified as Severe in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Fatal'. The Pruritus was classified as Life-threatening in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovered'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. A Naranjo score of 6 was calculated, The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Rechallenge not performed'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Risk take support. Her out begin instead. Federal check reduce.</data>
report_id: ADR-2025-338
report_date: '2025-02-10'
patient_details:
  patient_id: ANON-PX-6561
  gender: Other
  relevant_history:
  - atrial fibrillation
  - type 2 diabetes
  - coronary artery disease
  - hypertension
  age_at_reaction: 41
suspected_drugs:
- drug_name: Amoxicillin
  dosage: 377mg
  route_of_administration: Oral
  start_date: '2025-01-13'
  indication_for_use: Bacterial infection
  drug_class: Penicillin antibiotic
adverse_reactions:
- symptom_name: Anaphylaxis
  onset_date: '2025-01-20'
  severity: Mild
  outcome: Recovering
  intervention_required: false
- symptom_name: Nausea
  onset_date: '2025-01-20'
  severity: Mild
  outcome: Recovering
  intervention_required: false
- symptom_name: Headache
  onset_date: '2025-01-20'
  severity: Mild
  outcome: Recovering
  intervention_required: false
- symptom_name: Diarrhea
  onset_date: '2025-01-20'
  severity: Severe
  outcome: Fatal
  intervention_required: false
- symptom_name: Pruritus
  onset_date: '2025-01-20'
  severity: Life-threatening
  outcome: Recovered
  intervention_required: false
causality_assessment:
  assessment_conclusion: Probable
  dechallenge_rechallenge: Rechallenge not performed
  naranjo_score: 6
reporting_facility: Lane, Mckinney and Riddle Medical Center
reporter_type: Nurse
notes: Risk take support. Her out begin instead. Federal check reduce.
