<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2025-803
Date of Submission: 2025-03-07

This report was submitted by a Pharmacist from Williams, Scott and Rodriguez Medical Center concerning patient ANON-PX-9552. The subject is a 71-year-old female with a significant medical history including atrial fibrillation, osteoarthritis, coronary artery disease, migraines. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Atorvastatin (Statin) administered via the Intramuscular route at a dosage of 264mg, initiated on 2024-12-23 for Hypercholesterolemia and discontinued on 2025-03-03; Warfarin (Anticoagulant) administered via the Oral route at a dosage of 127mg, initiated on 2024-12-23 for Thromboembolism prevention and discontinued on 2025-03-03.

On approximately 2025-02-10, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Angioedema, Nausea, Pruritus, Headache. The Angioedema was classified as Moderate in severity. This necessitated clinical intervention. The current patient status regarding this symptom is 'Unknown'. The Nausea was classified as Severe in severity. This necessitated clinical intervention. The current patient status regarding this symptom is 'Unknown'. The Pruritus was classified as Life-threatening in severity. This necessitated clinical intervention. The documented action was: Prescribed appear and advised city. The current patient status regarding this symptom is 'Not Recovered'. The Headache was classified as Life-threatening in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovered'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Not applicable'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: So range time that fund player political. Star during goal husband develop.</data>
report_id: ADR-2025-803
report_date: '2025-03-07'
patient_details:
  patient_id: ANON-PX-9552
  gender: Female
  relevant_history:
  - atrial fibrillation
  - osteoarthritis
  - coronary artery disease
  - migraines
  age_at_reaction: 71
suspected_drugs:
- drug_name: Atorvastatin
  dosage: 264mg
  route_of_administration: Intramuscular
  start_date: '2024-12-23'
  indication_for_use: Hypercholesterolemia
  drug_class: Statin
  end_date: '2025-03-03'
- drug_name: Warfarin
  dosage: 127mg
  route_of_administration: Oral
  start_date: '2024-12-23'
  indication_for_use: Thromboembolism prevention
  drug_class: Anticoagulant
  end_date: '2025-03-03'
adverse_reactions:
- symptom_name: Angioedema
  onset_date: '2025-02-10'
  severity: Moderate
  outcome: Unknown
  intervention_required: true
- symptom_name: Nausea
  onset_date: '2025-02-10'
  severity: Severe
  outcome: Unknown
  intervention_required: true
- symptom_name: Pruritus
  onset_date: '2025-02-10'
  severity: Life-threatening
  outcome: Not Recovered
  intervention_required: true
  intervention_details: Prescribed appear and advised city.
- symptom_name: Headache
  onset_date: '2025-02-10'
  severity: Life-threatening
  outcome: Recovered
  intervention_required: false
causality_assessment:
  assessment_conclusion: Probable
  dechallenge_rechallenge: Not applicable
reporting_facility: Williams, Scott and Rodriguez Medical Center
reporter_type: Pharmacist
notes: So range time that fund player political. Star during goal husband develop.
