<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2025-620
Date of Submission: 2025-04-14

This report was submitted by a Pharmacist from Robbins PLC Medical Center concerning patient ANON-PX-5613. The subject is a 78-year-old female with a significant medical history including anxiety, migraines. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Ibuprofen administered via the Intramuscular route at a dosage of 113mg, initiated on 2025-03-24 for Pain and inflammation and discontinued on 2025-04-12.

On approximately 2025-03-30, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Somnolence, Nausea, Pruritus, Maculopapular Rash, Diarrhea. The Somnolence was classified as Moderate in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Fatal'. The Nausea was classified as Mild in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Unknown'. The Pruritus was classified as Moderate in severity. This necessitated clinical intervention. The current patient status regarding this symptom is 'Recovered'. The Maculopapular Rash was classified as Mild in severity. This necessitated clinical intervention. The documented action was: Prescribed Republican and advised trouble. The current patient status regarding this symptom is 'Unknown'. The Diarrhea was classified as Life-threatening in severity. This necessitated clinical intervention. The documented action was: Prescribed natural and advised attorney. The current patient status regarding this symptom is 'Recovered'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. A Naranjo score of 8 was calculated, The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Not applicable'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Give opportunity focus almost. Decision food center paper.</data>
report_id: ADR-2025-620
report_date: '2025-04-14'
patient_details:
  patient_id: ANON-PX-5613
  gender: Female
  relevant_history:
  - anxiety
  - migraines
  age_at_reaction: 78
suspected_drugs:
- drug_name: Ibuprofen
  dosage: 113mg
  route_of_administration: Intramuscular
  start_date: '2025-03-24'
  indication_for_use: Pain and inflammation
  end_date: '2025-04-12'
adverse_reactions:
- symptom_name: Somnolence
  onset_date: '2025-03-30'
  severity: Moderate
  outcome: Fatal
  intervention_required: false
- symptom_name: Nausea
  onset_date: '2025-03-30'
  severity: Mild
  outcome: Unknown
  intervention_required: false
- symptom_name: Pruritus
  onset_date: '2025-03-30'
  severity: Moderate
  outcome: Recovered
  intervention_required: true
- symptom_name: Maculopapular Rash
  onset_date: '2025-03-30'
  severity: Mild
  outcome: Unknown
  intervention_required: true
  intervention_details: Prescribed Republican and advised trouble.
- symptom_name: Diarrhea
  onset_date: '2025-03-30'
  severity: Life-threatening
  outcome: Recovered
  intervention_required: true
  intervention_details: Prescribed natural and advised attorney.
causality_assessment:
  assessment_conclusion: Probable
  dechallenge_rechallenge: Not applicable
  naranjo_score: 8
reporting_facility: Robbins PLC Medical Center
reporter_type: Pharmacist
notes: Give opportunity focus almost. Decision food center paper.
