<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2024-830
Date of Submission: 2024-08-26

This report was submitted by a Physician from Mcdowell Inc Medical Center concerning patient ANON-PX-1066. The subject is an adult female with a significant medical history including chronic kidney disease, anxiety, type 2 diabetes, coronary artery disease. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Ibuprofen (NSAID) administered via the Subcutaneous route at a dosage of 229mg, initiated on 2024-06-11 for Pain and inflammation with the course ongoing.

On approximately 2024-06-13, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Pruritus, Somnolence, Anaphylaxis, Stevens-Johnson syndrome, Maculopapular Rash. The Pruritus was classified as Severe in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Not Recovered'. The Somnolence was classified as Moderate in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovered'. The Anaphylaxis was classified as Severe in severity. This necessitated clinical intervention. The documented action was: Prescribed similar and advised color. The current patient status regarding this symptom is 'Fatal'. The Stevens-Johnson syndrome was classified as Mild in severity. This necessitated clinical intervention. The documented action was: Prescribed mouth and advised these. The current patient status regarding this symptom is 'Recovering'. The Maculopapular Rash was classified as Moderate in severity. This necessitated clinical intervention. The documented action was: Prescribed very and advised sit. The current patient status regarding this symptom is 'Unknown'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. A Naranjo score of 7 was calculated, The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Rechallenge not performed'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Push prepare yes look large set. Beyond what major member.</data>
report_id: ADR-2024-830
report_date: '2024-08-26'
patient_details:
  patient_id: ANON-PX-1066
  gender: Female
  relevant_history:
  - chronic kidney disease
  - anxiety
  - type 2 diabetes
  - coronary artery disease
suspected_drugs:
- drug_name: Ibuprofen
  dosage: 229mg
  route_of_administration: Subcutaneous
  start_date: '2024-06-11'
  indication_for_use: Pain and inflammation
  drug_class: NSAID
adverse_reactions:
- symptom_name: Pruritus
  onset_date: '2024-06-13'
  severity: Severe
  outcome: Not Recovered
  intervention_required: false
- symptom_name: Somnolence
  onset_date: '2024-06-13'
  severity: Moderate
  outcome: Recovered
  intervention_required: false
- symptom_name: Anaphylaxis
  onset_date: '2024-06-13'
  severity: Severe
  outcome: Fatal
  intervention_required: true
  intervention_details: Prescribed similar and advised color.
- symptom_name: Stevens-Johnson syndrome
  onset_date: '2024-06-13'
  severity: Mild
  outcome: Recovering
  intervention_required: true
  intervention_details: Prescribed mouth and advised these.
- symptom_name: Maculopapular Rash
  onset_date: '2024-06-13'
  severity: Moderate
  outcome: Unknown
  intervention_required: true
  intervention_details: Prescribed very and advised sit.
causality_assessment:
  assessment_conclusion: Probable
  dechallenge_rechallenge: Rechallenge not performed
  naranjo_score: 7
reporting_facility: Mcdowell Inc Medical Center
reporter_type: Physician
notes: Push prepare yes look large set. Beyond what major member.
