<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2024-195
Date of Submission: 2024-12-27

This report was submitted by a Nurse from Walker Ltd Medical Center concerning patient ANON-PX-3921. The subject is an adult other with a significant medical history including asthma, osteoarthritis, type 2 diabetes. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Omeprazole administered via the Intravenous route at a dosage of 459mg, initiated on 2024-11-20 for Gastroesophageal reflux disease and discontinued on 2024-12-24; Gabapentin administered via the Intramuscular route at a dosage of 375mg, initiated on 2024-11-20 for Neuropathic pain and discontinued on 2024-12-24.

On approximately 2024-12-10, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Anaphylaxis, Angioedema, Stevens-Johnson syndrome, Maculopapular Rash, Headache. The Anaphylaxis was classified as Moderate in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Unknown'. The Angioedema was classified as Severe in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Not Recovered'. The Stevens-Johnson syndrome was classified as Mild in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Fatal'. The Maculopapular Rash was classified as Moderate in severity. This necessitated clinical intervention. The documented action was: Prescribed put and advised section. The current patient status regarding this symptom is 'Fatal'. The Headache was classified as Severe in severity. This necessitated clinical intervention. The documented action was: Prescribed become and advised bank. The current patient status regarding this symptom is 'Recovered'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. A Naranjo score of 10 was calculated, The assessment concluded the relationship was 'Highly Probable'. Dechallenge/Rechallenge status was noted as: 'Negative dechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Table during onto culture theory concern player. Reflect television kind summer.</data>
report_id: ADR-2024-195
report_date: '2024-12-27'
patient_details:
  patient_id: ANON-PX-3921
  gender: Other
  relevant_history:
  - asthma
  - osteoarthritis
  - type 2 diabetes
suspected_drugs:
- drug_name: Omeprazole
  dosage: 459mg
  route_of_administration: Intravenous
  start_date: '2024-11-20'
  indication_for_use: Gastroesophageal reflux disease
  end_date: '2024-12-24'
- drug_name: Gabapentin
  dosage: 375mg
  route_of_administration: Intramuscular
  start_date: '2024-11-20'
  indication_for_use: Neuropathic pain
  end_date: '2024-12-24'
adverse_reactions:
- symptom_name: Anaphylaxis
  onset_date: '2024-12-10'
  severity: Moderate
  outcome: Unknown
  intervention_required: false
- symptom_name: Angioedema
  onset_date: '2024-12-10'
  severity: Severe
  outcome: Not Recovered
  intervention_required: false
- symptom_name: Stevens-Johnson syndrome
  onset_date: '2024-12-10'
  severity: Mild
  outcome: Fatal
  intervention_required: false
- symptom_name: Maculopapular Rash
  onset_date: '2024-12-10'
  severity: Moderate
  outcome: Fatal
  intervention_required: true
  intervention_details: Prescribed put and advised section.
- symptom_name: Headache
  onset_date: '2024-12-10'
  severity: Severe
  outcome: Recovered
  intervention_required: true
  intervention_details: Prescribed become and advised bank.
causality_assessment:
  assessment_conclusion: Highly Probable
  dechallenge_rechallenge: Negative dechallenge
  naranjo_score: 10
reporting_facility: Walker Ltd Medical Center
reporter_type: Nurse
notes: Table during onto culture theory concern player. Reflect television kind summer.
