<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2025-714
Date of Submission: 2025-08-03

This report was submitted by a Physician from Cox-Williams Medical Center concerning patient ANON-PX-2347. The subject is a 79-year-old other with a significant medical history including anxiety, type 2 diabetes, migraines. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Lisinopril (ACE inhibitor) administered via the Oral route at a dosage of 373mg, initiated on 2025-06-27 for Hypertension and discontinued on 2025-07-31.

On approximately 2025-07-19, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Headache, Dizziness. The Headache was classified as Life-threatening in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Not Recovered'. The Dizziness was classified as Mild in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Fatal'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. A Naranjo score of 8 was calculated, The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Rechallenge not performed'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Fish back drop firm. Design third five education collection professor cold.</data>
report_id: ADR-2025-714
report_date: '2025-08-03'
patient_details:
  patient_id: ANON-PX-2347
  gender: Other
  relevant_history:
  - anxiety
  - type 2 diabetes
  - migraines
  age_at_reaction: 79
suspected_drugs:
- drug_name: Lisinopril
  dosage: 373mg
  route_of_administration: Oral
  start_date: '2025-06-27'
  indication_for_use: Hypertension
  drug_class: ACE inhibitor
  end_date: '2025-07-31'
adverse_reactions:
- symptom_name: Headache
  onset_date: '2025-07-19'
  severity: Life-threatening
  outcome: Not Recovered
  intervention_required: false
- symptom_name: Dizziness
  onset_date: '2025-07-19'
  severity: Mild
  outcome: Fatal
  intervention_required: false
causality_assessment:
  assessment_conclusion: Probable
  dechallenge_rechallenge: Rechallenge not performed
  naranjo_score: 8
reporting_facility: Cox-Williams Medical Center
reporter_type: Physician
notes: Fish back drop firm. Design third five education collection professor cold.
