<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2024-235
Date of Submission: 2024-08-15

This report was submitted by a Pharmacist from Stokes-Torres Medical Center concerning patient ANON-PX-1339. The subject is an adult other with a significant medical history including chronic kidney disease, migraines. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Atorvastatin (Statin) administered via the Subcutaneous route at a dosage of 478mg, initiated on 2024-06-19 for Hypercholesterolemia and discontinued on 2024-07-14.

On approximately 2024-07-10, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Anaphylaxis, Hepatotoxicity, Nausea, Pruritus, Dizziness. The Anaphylaxis was classified as Moderate in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovered'. The Hepatotoxicity was classified as Mild in severity. This necessitated clinical intervention. The current patient status regarding this symptom is 'Fatal'. The Nausea was classified as Mild in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovering'. The Pruritus was classified as Life-threatening in severity. This necessitated clinical intervention. The documented action was: Prescribed across and advised him. The current patient status regarding this symptom is 'Not Recovered'. The Dizziness was classified as Severe in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovered'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Rechallenge not performed'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Lose cell growth not leader. World despite piece room.</data>
report_id: ADR-2024-235
report_date: '2024-08-15'
patient_details:
  patient_id: ANON-PX-1339
  gender: Other
  relevant_history:
  - chronic kidney disease
  - migraines
suspected_drugs:
- drug_name: Atorvastatin
  dosage: 478mg
  route_of_administration: Subcutaneous
  start_date: '2024-06-19'
  indication_for_use: Hypercholesterolemia
  drug_class: Statin
  end_date: '2024-07-14'
adverse_reactions:
- symptom_name: Anaphylaxis
  onset_date: '2024-07-10'
  severity: Moderate
  outcome: Recovered
  intervention_required: false
- symptom_name: Hepatotoxicity
  onset_date: '2024-07-10'
  severity: Mild
  outcome: Fatal
  intervention_required: true
- symptom_name: Nausea
  onset_date: '2024-07-10'
  severity: Mild
  outcome: Recovering
  intervention_required: false
- symptom_name: Pruritus
  onset_date: '2024-07-10'
  severity: Life-threatening
  outcome: Not Recovered
  intervention_required: true
  intervention_details: Prescribed across and advised him.
- symptom_name: Dizziness
  onset_date: '2024-07-10'
  severity: Severe
  outcome: Recovered
  intervention_required: false
causality_assessment:
  assessment_conclusion: Probable
  dechallenge_rechallenge: Rechallenge not performed
reporting_facility: Stokes-Torres Medical Center
reporter_type: Pharmacist
notes: Lose cell growth not leader. World despite piece room.
