<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2024-470
Date of Submission: 2024-12-28

This report was submitted by a Other Healthcare Professional from Campbell, Cunningham and French Medical Center concerning patient ANON-PX-1887. The subject is a 85-year-old male with a significant medical history including chronic kidney disease, anxiety. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Warfarin (Anticoagulant) administered via the Intravenous route at a dosage of 24mg, initiated on 2024-11-10 for Thromboembolism prevention and discontinued on 2024-12-23; Gabapentin (Anticonvulsant) administered via the Intravenous route at a dosage of 476mg, initiated on 2024-11-10 for Neuropathic pain and discontinued on 2024-12-23.

On approximately 2024-12-13, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Dizziness, Maculopapular Rash, Hepatotoxicity, Vomiting, Anaphylaxis. The Dizziness was classified as Severe in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Unknown'. The Maculopapular Rash was classified as Moderate in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Fatal'. The Hepatotoxicity was classified as Life-threatening in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Fatal'. The Vomiting was classified as Life-threatening in severity. This necessitated clinical intervention. The documented action was: Prescribed necessary and advised through. The current patient status regarding this symptom is 'Recovering'. The Anaphylaxis was classified as Moderate in severity. This necessitated clinical intervention. The current patient status regarding this symptom is 'Recovered'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Negative dechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Of large often window way away. Own nature west already.</data>
report_id: ADR-2024-470
report_date: '2024-12-28'
patient_details:
  patient_id: ANON-PX-1887
  gender: Male
  relevant_history:
  - chronic kidney disease
  - anxiety
  age_at_reaction: 85
suspected_drugs:
- drug_name: Warfarin
  dosage: 24mg
  route_of_administration: Intravenous
  start_date: '2024-11-10'
  indication_for_use: Thromboembolism prevention
  drug_class: Anticoagulant
  end_date: '2024-12-23'
- drug_name: Gabapentin
  dosage: 476mg
  route_of_administration: Intravenous
  start_date: '2024-11-10'
  indication_for_use: Neuropathic pain
  drug_class: Anticonvulsant
  end_date: '2024-12-23'
adverse_reactions:
- symptom_name: Dizziness
  onset_date: '2024-12-13'
  severity: Severe
  outcome: Unknown
  intervention_required: false
- symptom_name: Maculopapular Rash
  onset_date: '2024-12-13'
  severity: Moderate
  outcome: Fatal
  intervention_required: false
- symptom_name: Hepatotoxicity
  onset_date: '2024-12-13'
  severity: Life-threatening
  outcome: Fatal
  intervention_required: false
- symptom_name: Vomiting
  onset_date: '2024-12-13'
  severity: Life-threatening
  outcome: Recovering
  intervention_required: true
  intervention_details: Prescribed necessary and advised through.
- symptom_name: Anaphylaxis
  onset_date: '2024-12-13'
  severity: Moderate
  outcome: Recovered
  intervention_required: true
causality_assessment:
  assessment_conclusion: Probable
  dechallenge_rechallenge: Negative dechallenge
reporting_facility: Campbell, Cunningham and French Medical Center
reporter_type: Other Healthcare Professional
notes: Of large often window way away. Own nature west already.
