<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2025-553
Date of Submission: 2025-03-07

This report was submitted by a Pharmacist from Rodriguez-Garrett Medical Center concerning patient ANON-PX-1482. The subject is a 72-year-old male with a significant medical history including asthma, seasonal allergies, coronary artery disease. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Amoxicillin administered via the Subcutaneous route at a dosage of 404mg, initiated on 2025-02-17 for Bacterial infection and discontinued on 2025-03-03; Metformin (Biguanide) administered via the Intravenous route at a dosage of 77mg, initiated on 2025-02-17 for Type 2 diabetes and discontinued on 2025-03-03.

On approximately 2025-03-03, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Somnolence, Maculopapular Rash, Headache, Stevens-Johnson syndrome. The Somnolence was classified as Severe in severity. This necessitated clinical intervention. The documented action was: Prescribed resource and advised teacher. The current patient status regarding this symptom is 'Unknown'. The Maculopapular Rash was classified as Mild in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Unknown'. The Headache was classified as Moderate in severity. This necessitated clinical intervention. The current patient status regarding this symptom is 'Recovering'. The Stevens-Johnson syndrome was classified as Mild in severity. This necessitated clinical intervention. The current patient status regarding this symptom is 'Unknown'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. A Naranjo score of 4 was calculated, The assessment concluded the relationship was 'Possible'. Dechallenge/Rechallenge status was noted as: 'Not applicable'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Must message plan condition agency. Modern hour agent loss boy tax western thousand.</data>
report_id: ADR-2025-553
report_date: '2025-03-07'
patient_details:
  patient_id: ANON-PX-1482
  gender: Male
  relevant_history:
  - asthma
  - seasonal allergies
  - coronary artery disease
  age_at_reaction: 72
suspected_drugs:
- drug_name: Amoxicillin
  dosage: 404mg
  route_of_administration: Subcutaneous
  start_date: '2025-02-17'
  indication_for_use: Bacterial infection
  end_date: '2025-03-03'
- drug_name: Metformin
  dosage: 77mg
  route_of_administration: Intravenous
  start_date: '2025-02-17'
  indication_for_use: Type 2 diabetes
  drug_class: Biguanide
  end_date: '2025-03-03'
adverse_reactions:
- symptom_name: Somnolence
  onset_date: '2025-03-03'
  severity: Severe
  outcome: Unknown
  intervention_required: true
  intervention_details: Prescribed resource and advised teacher.
- symptom_name: Maculopapular Rash
  onset_date: '2025-03-03'
  severity: Mild
  outcome: Unknown
  intervention_required: false
- symptom_name: Headache
  onset_date: '2025-03-03'
  severity: Moderate
  outcome: Recovering
  intervention_required: true
- symptom_name: Stevens-Johnson syndrome
  onset_date: '2025-03-03'
  severity: Mild
  outcome: Unknown
  intervention_required: true
causality_assessment:
  assessment_conclusion: Possible
  dechallenge_rechallenge: Not applicable
  naranjo_score: 4
reporting_facility: Rodriguez-Garrett Medical Center
reporter_type: Pharmacist
notes: Must message plan condition agency. Modern hour agent loss boy tax western
  thousand.
