<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2024-158
Date of Submission: 2024-12-25

This report was submitted by a Patient from Hurley-Walter Medical Center concerning patient ANON-PX-4435. The subject is an adult female with a significant medical history including migraines, atrial fibrillation, seasonal allergies, type 2 diabetes. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Omeprazole (Proton-pump inhibitor) administered via the Intravenous route at a dosage of 486mg, initiated on 2024-11-30 for Gastroesophageal reflux disease and discontinued on 2024-12-17.

On approximately 2024-12-16, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Angioedema, Nausea, Stevens-Johnson syndrome, Diarrhea, Anaphylaxis. The Angioedema was classified as Severe in severity. This necessitated clinical intervention. The current patient status regarding this symptom is 'Not Recovered'. The Nausea was classified as Mild in severity. This necessitated clinical intervention. The documented action was: Prescribed company and advised executive. The current patient status regarding this symptom is 'Fatal'. The Stevens-Johnson syndrome was classified as Moderate in severity. This necessitated clinical intervention. The documented action was: Prescribed drug and advised smile. The current patient status regarding this symptom is 'Recovered'. The Diarrhea was classified as Mild in severity. This necessitated clinical intervention. The documented action was: Prescribed listen and advised trip. The current patient status regarding this symptom is 'Recovered'. The Anaphylaxis was classified as Severe in severity. This necessitated clinical intervention. The documented action was: Prescribed beautiful and advised nature. The current patient status regarding this symptom is 'Fatal'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. A Naranjo score of 2 was calculated, The assessment concluded the relationship was 'Possible'. Dechallenge/Rechallenge status was noted as: 'Rechallenge not performed'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Billion move go quite PM draw analysis. Point sister protect be billion food.</data>
report_id: ADR-2024-158
report_date: '2024-12-25'
patient_details:
  patient_id: ANON-PX-4435
  gender: Female
  relevant_history:
  - migraines
  - atrial fibrillation
  - seasonal allergies
  - type 2 diabetes
suspected_drugs:
- drug_name: Omeprazole
  dosage: 486mg
  route_of_administration: Intravenous
  start_date: '2024-11-30'
  indication_for_use: Gastroesophageal reflux disease
  drug_class: Proton-pump inhibitor
  end_date: '2024-12-17'
adverse_reactions:
- symptom_name: Angioedema
  onset_date: '2024-12-16'
  severity: Severe
  outcome: Not Recovered
  intervention_required: true
- symptom_name: Nausea
  onset_date: '2024-12-16'
  severity: Mild
  outcome: Fatal
  intervention_required: true
  intervention_details: Prescribed company and advised executive.
- symptom_name: Stevens-Johnson syndrome
  onset_date: '2024-12-16'
  severity: Moderate
  outcome: Recovered
  intervention_required: true
  intervention_details: Prescribed drug and advised smile.
- symptom_name: Diarrhea
  onset_date: '2024-12-16'
  severity: Mild
  outcome: Recovered
  intervention_required: true
  intervention_details: Prescribed listen and advised trip.
- symptom_name: Anaphylaxis
  onset_date: '2024-12-16'
  severity: Severe
  outcome: Fatal
  intervention_required: true
  intervention_details: Prescribed beautiful and advised nature.
causality_assessment:
  assessment_conclusion: Possible
  dechallenge_rechallenge: Rechallenge not performed
  naranjo_score: 2
reporting_facility: Hurley-Walter Medical Center
reporter_type: Patient
notes: Billion move go quite PM draw analysis. Point sister protect be billion food.
