<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2025-650
Date of Submission: 2025-07-20

This report was submitted by a Nurse from Snyder, Hayden and Ray Medical Center concerning patient ANON-PX-1249. The subject is a 67-year-old male with a significant medical history including seasonal allergies, anxiety, osteoarthritis. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Omeprazole (Proton-pump inhibitor) administered via the Subcutaneous route at a dosage of 420mg, initiated on 2025-05-16 for Gastroesophageal reflux disease with the course ongoing; Sertraline (SSRI) administered via the Subcutaneous route at a dosage of 375mg, initiated on 2025-05-16 for Major depressive disorder with the course ongoing.

On approximately 2025-06-28, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Diarrhea, Nausea. The Diarrhea was classified as Life-threatening in severity. This necessitated clinical intervention. The documented action was: Prescribed new and advised rather. The current patient status regarding this symptom is 'Recovered'. The Nausea was classified as Severe in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovered'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. A Naranjo score of 3 was calculated, The assessment concluded the relationship was 'Possible'. Dechallenge/Rechallenge status was noted as: 'Rechallenge not performed'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Throughout value beyond significant happen study. Structure memory year bank always per PM agreement.</data>
report_id: ADR-2025-650
report_date: '2025-07-20'
patient_details:
  patient_id: ANON-PX-1249
  gender: Male
  relevant_history:
  - seasonal allergies
  - anxiety
  - osteoarthritis
  age_at_reaction: 67
suspected_drugs:
- drug_name: Omeprazole
  dosage: 420mg
  route_of_administration: Subcutaneous
  start_date: '2025-05-16'
  indication_for_use: Gastroesophageal reflux disease
  drug_class: Proton-pump inhibitor
- drug_name: Sertraline
  dosage: 375mg
  route_of_administration: Subcutaneous
  start_date: '2025-05-16'
  indication_for_use: Major depressive disorder
  drug_class: SSRI
adverse_reactions:
- symptom_name: Diarrhea
  onset_date: '2025-06-28'
  severity: Life-threatening
  outcome: Recovered
  intervention_required: true
  intervention_details: Prescribed new and advised rather.
- symptom_name: Nausea
  onset_date: '2025-06-28'
  severity: Severe
  outcome: Recovered
  intervention_required: false
causality_assessment:
  assessment_conclusion: Possible
  dechallenge_rechallenge: Rechallenge not performed
  naranjo_score: 3
reporting_facility: Snyder, Hayden and Ray Medical Center
reporter_type: Nurse
notes: Throughout value beyond significant happen study. Structure memory year bank
  always per PM agreement.
