<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2025-127
Date of Submission: 2025-03-07

This report was submitted by a Patient from Miller, Baker and Little Medical Center concerning patient ANON-PX-1549. The subject is a 84-year-old female with a significant medical history including hypertension, osteoarthritis, atrial fibrillation. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Metformin administered via the Intravenous route at a dosage of 309mg, initiated on 2024-12-07 for Type 2 diabetes with the course ongoing; Amoxicillin (Penicillin antibiotic) administered via the Intravenous route at a dosage of 381mg, initiated on 2024-12-07 for Bacterial infection with the course ongoing.

On approximately 2024-12-09, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Somnolence, Headache. The Somnolence was classified as Life-threatening in severity. This necessitated clinical intervention. The documented action was: Prescribed condition and advised share. The current patient status regarding this symptom is 'Unknown'. The Headache was classified as Moderate in severity. This necessitated clinical intervention. The documented action was: Prescribed fund and advised painting. The current patient status regarding this symptom is 'Recovering'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Negative dechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: True figure physical. Style fly industry box.</data>
report_id: ADR-2025-127
report_date: '2025-03-07'
patient_details:
  patient_id: ANON-PX-1549
  gender: Female
  relevant_history:
  - hypertension
  - osteoarthritis
  - atrial fibrillation
  age_at_reaction: 84
suspected_drugs:
- drug_name: Metformin
  dosage: 309mg
  route_of_administration: Intravenous
  start_date: '2024-12-07'
  indication_for_use: Type 2 diabetes
- drug_name: Amoxicillin
  dosage: 381mg
  route_of_administration: Intravenous
  start_date: '2024-12-07'
  indication_for_use: Bacterial infection
  drug_class: Penicillin antibiotic
adverse_reactions:
- symptom_name: Somnolence
  onset_date: '2024-12-09'
  severity: Life-threatening
  outcome: Unknown
  intervention_required: true
  intervention_details: Prescribed condition and advised share.
- symptom_name: Headache
  onset_date: '2024-12-09'
  severity: Moderate
  outcome: Recovering
  intervention_required: true
  intervention_details: Prescribed fund and advised painting.
causality_assessment:
  assessment_conclusion: Probable
  dechallenge_rechallenge: Negative dechallenge
reporting_facility: Miller, Baker and Little Medical Center
reporter_type: Patient
notes: True figure physical. Style fly industry box.
