<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2024-845
Date of Submission: 2024-09-21

This report was submitted by a Other Healthcare Professional from Griffith Inc Medical Center concerning patient ANON-PX-5750. The subject is a 70-year-old other with a significant medical history including seasonal allergies, type 2 diabetes, coronary artery disease. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Metformin (Biguanide) administered via the Oral route at a dosage of 158mg, initiated on 2024-07-11 for Type 2 diabetes with the course ongoing.

On approximately 2024-08-16, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Headache, Dizziness, Nausea, Stevens-Johnson syndrome, Maculopapular Rash. The Headache was classified as Severe in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovered'. The Dizziness was classified as Moderate in severity. This necessitated clinical intervention. The documented action was: Prescribed church and advised manager. The current patient status regarding this symptom is 'Not Recovered'. The Nausea was classified as Mild in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Fatal'. The Stevens-Johnson syndrome was classified as Moderate in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovering'. The Maculopapular Rash was classified as Mild in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Fatal'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Rechallenge not performed'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Among meet threat. Never into how include.</data>
report_id: ADR-2024-845
report_date: '2024-09-21'
patient_details:
  patient_id: ANON-PX-5750
  gender: Other
  relevant_history:
  - seasonal allergies
  - type 2 diabetes
  - coronary artery disease
  age_at_reaction: 70
suspected_drugs:
- drug_name: Metformin
  dosage: 158mg
  route_of_administration: Oral
  start_date: '2024-07-11'
  indication_for_use: Type 2 diabetes
  drug_class: Biguanide
adverse_reactions:
- symptom_name: Headache
  onset_date: '2024-08-16'
  severity: Severe
  outcome: Recovered
  intervention_required: false
- symptom_name: Dizziness
  onset_date: '2024-08-16'
  severity: Moderate
  outcome: Not Recovered
  intervention_required: true
  intervention_details: Prescribed church and advised manager.
- symptom_name: Nausea
  onset_date: '2024-08-16'
  severity: Mild
  outcome: Fatal
  intervention_required: false
- symptom_name: Stevens-Johnson syndrome
  onset_date: '2024-08-16'
  severity: Moderate
  outcome: Recovering
  intervention_required: false
- symptom_name: Maculopapular Rash
  onset_date: '2024-08-16'
  severity: Mild
  outcome: Fatal
  intervention_required: false
causality_assessment:
  assessment_conclusion: Probable
  dechallenge_rechallenge: Rechallenge not performed
reporting_facility: Griffith Inc Medical Center
reporter_type: Other Healthcare Professional
notes: Among meet threat. Never into how include.
