<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2024-459
Date of Submission: 2024-09-04

This report was submitted by a Pharmacist from Taylor-Patterson Medical Center concerning patient ANON-PX-4503. The subject is a 48-year-old female with a significant medical history including seasonal allergies, hypertension, asthma, osteoarthritis. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Omeprazole administered via the Topical route at a dosage of 433mg, initiated on 2024-07-18 for Gastroesophageal reflux disease with the course ongoing.

On approximately 2024-08-14, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Headache, Nausea. The Headache was classified as Severe in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovering'. The Nausea was classified as Mild in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Fatal'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. A Naranjo score of 10 was calculated, The assessment concluded the relationship was 'Highly Probable'. Dechallenge/Rechallenge status was noted as: 'Positive rechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Discover food she international knowledge source down. Since follow skill. Argue gun campaign.</data>
report_id: ADR-2024-459
report_date: '2024-09-04'
patient_details:
  patient_id: ANON-PX-4503
  gender: Female
  relevant_history:
  - seasonal allergies
  - hypertension
  - asthma
  - osteoarthritis
  age_at_reaction: 48
suspected_drugs:
- drug_name: Omeprazole
  dosage: 433mg
  route_of_administration: Topical
  start_date: '2024-07-18'
  indication_for_use: Gastroesophageal reflux disease
adverse_reactions:
- symptom_name: Headache
  onset_date: '2024-08-14'
  severity: Severe
  outcome: Recovering
  intervention_required: false
- symptom_name: Nausea
  onset_date: '2024-08-14'
  severity: Mild
  outcome: Fatal
  intervention_required: false
causality_assessment:
  assessment_conclusion: Highly Probable
  dechallenge_rechallenge: Positive rechallenge
  naranjo_score: 10
reporting_facility: Taylor-Patterson Medical Center
reporter_type: Pharmacist
notes: Discover food she international knowledge source down. Since follow skill.
  Argue gun campaign.
