<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2024-216
Date of Submission: 2024-09-28

This report was submitted by a Nurse from White-Boone Medical Center concerning patient ANON-PX-4284. The subject is a 20-year-old female with a significant medical history including migraines, type 2 diabetes. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Warfarin administered via the Intravenous route at a dosage of 324mg, initiated on 2024-08-31 for Thromboembolism prevention and discontinued on 2024-09-11; Amoxicillin (Penicillin antibiotic) administered via the Topical route at a dosage of 125mg, initiated on 2024-08-31 for Bacterial infection and discontinued on 2024-09-11.

On approximately 2024-09-02, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Stevens-Johnson syndrome, Dizziness. The Stevens-Johnson syndrome was classified as Severe in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Fatal'. The Dizziness was classified as Moderate in severity. This necessitated clinical intervention. The documented action was: Prescribed property and advised rather. The current patient status regarding this symptom is 'Recovered'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. A Naranjo score of 2 was calculated, The assessment concluded the relationship was 'Possible'. Dechallenge/Rechallenge status was noted as: 'Negative dechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Way show authority series. Shake live consider land stuff run same. Industry everyone nice.</data>
report_id: ADR-2024-216
report_date: '2024-09-28'
patient_details:
  patient_id: ANON-PX-4284
  gender: Female
  relevant_history:
  - migraines
  - type 2 diabetes
  age_at_reaction: 20
suspected_drugs:
- drug_name: Warfarin
  dosage: 324mg
  route_of_administration: Intravenous
  start_date: '2024-08-31'
  indication_for_use: Thromboembolism prevention
  end_date: '2024-09-11'
- drug_name: Amoxicillin
  dosage: 125mg
  route_of_administration: Topical
  start_date: '2024-08-31'
  indication_for_use: Bacterial infection
  drug_class: Penicillin antibiotic
  end_date: '2024-09-11'
adverse_reactions:
- symptom_name: Stevens-Johnson syndrome
  onset_date: '2024-09-02'
  severity: Severe
  outcome: Fatal
  intervention_required: false
- symptom_name: Dizziness
  onset_date: '2024-09-02'
  severity: Moderate
  outcome: Recovered
  intervention_required: true
  intervention_details: Prescribed property and advised rather.
causality_assessment:
  assessment_conclusion: Possible
  dechallenge_rechallenge: Negative dechallenge
  naranjo_score: 2
reporting_facility: White-Boone Medical Center
reporter_type: Nurse
notes: Way show authority series. Shake live consider land stuff run same. Industry
  everyone nice.
