<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2024-686
Date of Submission: 2024-09-10

This report was submitted by a Pharmacist from Moore and Sons Medical Center concerning patient ANON-PX-8978. The subject is an adult other with a significant medical history including chronic kidney disease, hypertension. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Sertraline (SSRI) administered via the Intravenous route at a dosage of 187mg, initiated on 2024-08-03 for Major depressive disorder and discontinued on 2024-08-29; Levothyroxine (Thyroid hormone) administered via the Intravenous route at a dosage of 408mg, initiated on 2024-08-03 for Hypothyroidism and discontinued on 2024-08-29.

On approximately 2024-08-24, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Vomiting, Anaphylaxis. The Vomiting was classified as Moderate in severity. This necessitated clinical intervention. The documented action was: Prescribed standard and advised everyone. The current patient status regarding this symptom is 'Recovering'. The Anaphylaxis was classified as Severe in severity. This necessitated clinical intervention. The documented action was: Prescribed play and advised have. The current patient status regarding this symptom is 'Recovering'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. A Naranjo score of 4 was calculated, The assessment concluded the relationship was 'Possible'. Dechallenge/Rechallenge status was noted as: 'Positive dechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Enough truth she leg. Newspaper be prevent school style. Again south world herself six could.</data>
report_id: ADR-2024-686
report_date: '2024-09-10'
patient_details:
  patient_id: ANON-PX-8978
  gender: Other
  relevant_history:
  - chronic kidney disease
  - hypertension
suspected_drugs:
- drug_name: Sertraline
  dosage: 187mg
  route_of_administration: Intravenous
  start_date: '2024-08-03'
  indication_for_use: Major depressive disorder
  drug_class: SSRI
  end_date: '2024-08-29'
- drug_name: Levothyroxine
  dosage: 408mg
  route_of_administration: Intravenous
  start_date: '2024-08-03'
  indication_for_use: Hypothyroidism
  drug_class: Thyroid hormone
  end_date: '2024-08-29'
adverse_reactions:
- symptom_name: Vomiting
  onset_date: '2024-08-24'
  severity: Moderate
  outcome: Recovering
  intervention_required: true
  intervention_details: Prescribed standard and advised everyone.
- symptom_name: Anaphylaxis
  onset_date: '2024-08-24'
  severity: Severe
  outcome: Recovering
  intervention_required: true
  intervention_details: Prescribed play and advised have.
causality_assessment:
  assessment_conclusion: Possible
  dechallenge_rechallenge: Positive dechallenge
  naranjo_score: 4
reporting_facility: Moore and Sons Medical Center
reporter_type: Pharmacist
notes: Enough truth she leg. Newspaper be prevent school style. Again south world
  herself six could.
