<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2025-271
Date of Submission: 2025-08-05

This report was submitted by a Nurse from Johnson, Frederick and Patel Medical Center concerning patient ANON-PX-1543. The subject is a 35-year-old male with a significant medical history including anxiety, chronic kidney disease, hypertension. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Gabapentin (Anticonvulsant) administered via the Intravenous route at a dosage of 455mg, initiated on 2025-07-14 for Neuropathic pain and discontinued on 2025-07-31; Warfarin administered via the Intramuscular route at a dosage of 337mg, initiated on 2025-07-14 for Thromboembolism prevention and discontinued on 2025-07-31.

On approximately 2025-07-29, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Pruritus, Nausea, Stevens-Johnson syndrome, Headache. The Pruritus was classified as Mild in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovering'. The Nausea was classified as Moderate in severity. This necessitated clinical intervention. The documented action was: Prescribed summer and advised our. The current patient status regarding this symptom is 'Recovered'. The Stevens-Johnson syndrome was classified as Mild in severity. This necessitated clinical intervention. The documented action was: Prescribed though and advised computer. The current patient status regarding this symptom is 'Unknown'. The Headache was classified as Life-threatening in severity. This necessitated clinical intervention. The documented action was: Prescribed list and advised within. The current patient status regarding this symptom is 'Unknown'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. A Naranjo score of 6 was calculated, The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Not applicable'. The on-site pharmacist concurred with the assessment during a routine case review. 

</data>
report_id: ADR-2025-271
report_date: '2025-08-05'
patient_details:
  patient_id: ANON-PX-1543
  gender: Male
  relevant_history:
  - anxiety
  - chronic kidney disease
  - hypertension
  age_at_reaction: 35
suspected_drugs:
- drug_name: Gabapentin
  dosage: 455mg
  route_of_administration: Intravenous
  start_date: '2025-07-14'
  indication_for_use: Neuropathic pain
  drug_class: Anticonvulsant
  end_date: '2025-07-31'
- drug_name: Warfarin
  dosage: 337mg
  route_of_administration: Intramuscular
  start_date: '2025-07-14'
  indication_for_use: Thromboembolism prevention
  end_date: '2025-07-31'
adverse_reactions:
- symptom_name: Pruritus
  onset_date: '2025-07-29'
  severity: Mild
  outcome: Recovering
  intervention_required: false
- symptom_name: Nausea
  onset_date: '2025-07-29'
  severity: Moderate
  outcome: Recovered
  intervention_required: true
  intervention_details: Prescribed summer and advised our.
- symptom_name: Stevens-Johnson syndrome
  onset_date: '2025-07-29'
  severity: Mild
  outcome: Unknown
  intervention_required: true
  intervention_details: Prescribed though and advised computer.
- symptom_name: Headache
  onset_date: '2025-07-29'
  severity: Life-threatening
  outcome: Unknown
  intervention_required: true
  intervention_details: Prescribed list and advised within.
causality_assessment:
  assessment_conclusion: Probable
  dechallenge_rechallenge: Not applicable
  naranjo_score: 6
reporting_facility: Johnson, Frederick and Patel Medical Center
reporter_type: Nurse
