<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2025-361
Date of Submission: 2025-07-17

This report was submitted by a Pharmacist from Johnson-Richardson Medical Center concerning patient ANON-PX-3754. The subject is a 71-year-old male with a significant medical history including anxiety, hypertension, atrial fibrillation, migraines. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Amoxicillin (Penicillin antibiotic) administered via the Subcutaneous route at a dosage of 269mg, initiated on 2025-05-29 for Bacterial infection with the course ongoing.

On approximately 2025-06-14, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Anaphylaxis, Angioedema. The Anaphylaxis was classified as Moderate in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovering'. The Angioedema was classified as Moderate in severity. This necessitated clinical intervention. The documented action was: Prescribed money and advised audience. The current patient status regarding this symptom is 'Not Recovered'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. A Naranjo score of 6 was calculated, The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Rechallenge not performed'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Any group opportunity second senior person matter production. Usually indeed similar difficult. Throughout message game dog take candidate.</data>
report_id: ADR-2025-361
report_date: '2025-07-17'
patient_details:
  patient_id: ANON-PX-3754
  gender: Male
  relevant_history:
  - anxiety
  - hypertension
  - atrial fibrillation
  - migraines
  age_at_reaction: 71
suspected_drugs:
- drug_name: Amoxicillin
  dosage: 269mg
  route_of_administration: Subcutaneous
  start_date: '2025-05-29'
  indication_for_use: Bacterial infection
  drug_class: Penicillin antibiotic
adverse_reactions:
- symptom_name: Anaphylaxis
  onset_date: '2025-06-14'
  severity: Moderate
  outcome: Recovering
  intervention_required: false
- symptom_name: Angioedema
  onset_date: '2025-06-14'
  severity: Moderate
  outcome: Not Recovered
  intervention_required: true
  intervention_details: Prescribed money and advised audience.
causality_assessment:
  assessment_conclusion: Probable
  dechallenge_rechallenge: Rechallenge not performed
  naranjo_score: 6
reporting_facility: Johnson-Richardson Medical Center
reporter_type: Pharmacist
notes: Any group opportunity second senior person matter production. Usually indeed
  similar difficult. Throughout message game dog take candidate.
