<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2025-885
Date of Submission: 2025-02-27

This report was submitted by a Nurse from Espinoza, Burnett and Butler Medical Center concerning patient ANON-PX-6402. The subject is a 56-year-old other with a significant medical history including asthma, osteoarthritis, seasonal allergies. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Warfarin administered via the Topical route at a dosage of 98mg, initiated on 2024-12-06 for Thromboembolism prevention and discontinued on 2025-02-19.

On approximately 2025-01-13, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Dizziness, Stevens-Johnson syndrome. The Dizziness was classified as Life-threatening in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Unknown'. The Stevens-Johnson syndrome was classified as Severe in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovered'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. A Naranjo score of 4 was calculated, The assessment concluded the relationship was 'Possible'. Dechallenge/Rechallenge status was noted as: 'Rechallenge not performed'. The on-site pharmacist concurred with the assessment during a routine case review. 

</data>
report_id: ADR-2025-885
report_date: '2025-02-27'
patient_details:
  patient_id: ANON-PX-6402
  gender: Other
  relevant_history:
  - asthma
  - osteoarthritis
  - seasonal allergies
  age_at_reaction: 56
suspected_drugs:
- drug_name: Warfarin
  dosage: 98mg
  route_of_administration: Topical
  start_date: '2024-12-06'
  indication_for_use: Thromboembolism prevention
  end_date: '2025-02-19'
adverse_reactions:
- symptom_name: Dizziness
  onset_date: '2025-01-13'
  severity: Life-threatening
  outcome: Unknown
  intervention_required: false
- symptom_name: Stevens-Johnson syndrome
  onset_date: '2025-01-13'
  severity: Severe
  outcome: Recovered
  intervention_required: false
causality_assessment:
  assessment_conclusion: Possible
  dechallenge_rechallenge: Rechallenge not performed
  naranjo_score: 4
reporting_facility: Espinoza, Burnett and Butler Medical Center
reporter_type: Nurse
