<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2025-944
Date of Submission: 2025-01-12

This report was submitted by a Nurse from Smith and Sons Medical Center concerning patient ANON-PX-7700. The subject is a 88-year-old female with a significant medical history including hypertension, migraines. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Sertraline (SSRI) administered via the Topical route at a dosage of 10mg, initiated on 2024-10-28 for Major depressive disorder with the course ongoing; Omeprazole (Proton-pump inhibitor) administered via the Oral route at a dosage of 315mg, initiated on 2024-10-28 for Gastroesophageal reflux disease with the course ongoing.

On approximately 2024-12-22, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Angioedema, Anaphylaxis, Nausea. The Angioedema was classified as Mild in severity. This necessitated clinical intervention. The documented action was: Prescribed job and advised admit. The current patient status regarding this symptom is 'Recovering'. The Anaphylaxis was classified as Life-threatening in severity. This necessitated clinical intervention. The documented action was: Prescribed else and advised name. The current patient status regarding this symptom is 'Recovering'. The Nausea was classified as Severe in severity. This necessitated clinical intervention. The documented action was: Prescribed stage and advised more. The current patient status regarding this symptom is 'Not Recovered'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. A Naranjo score of 7 was calculated, The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Negative dechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Else thus water student science. Yourself cover individual note work decide successful research.</data>
report_id: ADR-2025-944
report_date: '2025-01-12'
patient_details:
  patient_id: ANON-PX-7700
  gender: Female
  relevant_history:
  - hypertension
  - migraines
  age_at_reaction: 88
suspected_drugs:
- drug_name: Sertraline
  dosage: 10mg
  route_of_administration: Topical
  start_date: '2024-10-28'
  indication_for_use: Major depressive disorder
  drug_class: SSRI
- drug_name: Omeprazole
  dosage: 315mg
  route_of_administration: Oral
  start_date: '2024-10-28'
  indication_for_use: Gastroesophageal reflux disease
  drug_class: Proton-pump inhibitor
adverse_reactions:
- symptom_name: Angioedema
  onset_date: '2024-12-22'
  severity: Mild
  outcome: Recovering
  intervention_required: true
  intervention_details: Prescribed job and advised admit.
- symptom_name: Anaphylaxis
  onset_date: '2024-12-22'
  severity: Life-threatening
  outcome: Recovering
  intervention_required: true
  intervention_details: Prescribed else and advised name.
- symptom_name: Nausea
  onset_date: '2024-12-22'
  severity: Severe
  outcome: Not Recovered
  intervention_required: true
  intervention_details: Prescribed stage and advised more.
causality_assessment:
  assessment_conclusion: Probable
  dechallenge_rechallenge: Negative dechallenge
  naranjo_score: 7
reporting_facility: Smith and Sons Medical Center
reporter_type: Nurse
notes: Else thus water student science. Yourself cover individual note work decide
  successful research.
