<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2025-236
Date of Submission: 2025-07-27

This report was submitted by a Patient from Salazar-Molina Medical Center concerning patient ANON-PX-3011. The subject is a 32-year-old male with a significant medical history including anxiety, migraines, osteoarthritis, type 2 diabetes. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Atorvastatin (Statin) administered via the Topical route at a dosage of 347mg, initiated on 2025-05-25 for Hypercholesterolemia and discontinued on 2025-07-23; Ibuprofen (NSAID) administered via the Intramuscular route at a dosage of 352mg, initiated on 2025-05-25 for Pain and inflammation and discontinued on 2025-07-23.

On approximately 2025-07-18, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Dizziness, Stevens-Johnson syndrome, Hepatotoxicity. The Dizziness was classified as Mild in severity. This necessitated clinical intervention. The documented action was: Prescribed local and advised everything. The current patient status regarding this symptom is 'Not Recovered'. The Stevens-Johnson syndrome was classified as Severe in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Not Recovered'. The Hepatotoxicity was classified as Severe in severity. This necessitated clinical intervention. The documented action was: Prescribed rate and advised cut. The current patient status regarding this symptom is 'Recovering'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Rechallenge not performed'. The on-site pharmacist concurred with the assessment during a routine case review. 

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report_id: ADR-2025-236
report_date: '2025-07-27'
patient_details:
  patient_id: ANON-PX-3011
  gender: Male
  relevant_history:
  - anxiety
  - migraines
  - osteoarthritis
  - type 2 diabetes
  age_at_reaction: 32
suspected_drugs:
- drug_name: Atorvastatin
  dosage: 347mg
  route_of_administration: Topical
  start_date: '2025-05-25'
  indication_for_use: Hypercholesterolemia
  drug_class: Statin
  end_date: '2025-07-23'
- drug_name: Ibuprofen
  dosage: 352mg
  route_of_administration: Intramuscular
  start_date: '2025-05-25'
  indication_for_use: Pain and inflammation
  drug_class: NSAID
  end_date: '2025-07-23'
adverse_reactions:
- symptom_name: Dizziness
  onset_date: '2025-07-18'
  severity: Mild
  outcome: Not Recovered
  intervention_required: true
  intervention_details: Prescribed local and advised everything.
- symptom_name: Stevens-Johnson syndrome
  onset_date: '2025-07-18'
  severity: Severe
  outcome: Not Recovered
  intervention_required: false
- symptom_name: Hepatotoxicity
  onset_date: '2025-07-18'
  severity: Severe
  outcome: Recovering
  intervention_required: true
  intervention_details: Prescribed rate and advised cut.
causality_assessment:
  assessment_conclusion: Probable
  dechallenge_rechallenge: Rechallenge not performed
reporting_facility: Salazar-Molina Medical Center
reporter_type: Patient
notes: Best forward north avoid dark administration visit. Family this girl stuff
  Democrat development. Current half notice low yes.
