<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2024-114
Date of Submission: 2024-08-17

This report was submitted by a Other Healthcare Professional from Foster, Cook and Patton Medical Center concerning patient ANON-PX-9246. The subject is a 25-year-old male with a significant medical history including anxiety, type 2 diabetes, hypertension, migraines. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Warfarin (Anticoagulant) administered via the Intramuscular route at a dosage of 41mg, initiated on 2024-05-30 for Thromboembolism prevention with the course ongoing; Ibuprofen (NSAID) administered via the Intravenous route at a dosage of 50mg, initiated on 2024-05-30 for Pain and inflammation with the course ongoing.

On approximately 2024-06-15, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Stevens-Johnson syndrome, Diarrhea. The Stevens-Johnson syndrome was classified as Life-threatening in severity. This necessitated clinical intervention. The current patient status regarding this symptom is 'Not Recovered'. The Diarrhea was classified as Moderate in severity. This necessitated clinical intervention. The current patient status regarding this symptom is 'Unknown'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. A Naranjo score of 8 was calculated, The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Negative dechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Administration opportunity air. Politics consumer simply white serve most history. Their task method collection.</data>
report_id: ADR-2024-114
report_date: '2024-08-17'
patient_details:
  patient_id: ANON-PX-9246
  gender: Male
  relevant_history:
  - anxiety
  - type 2 diabetes
  - hypertension
  - migraines
  age_at_reaction: 25
suspected_drugs:
- drug_name: Warfarin
  dosage: 41mg
  route_of_administration: Intramuscular
  start_date: '2024-05-30'
  indication_for_use: Thromboembolism prevention
  drug_class: Anticoagulant
- drug_name: Ibuprofen
  dosage: 50mg
  route_of_administration: Intravenous
  start_date: '2024-05-30'
  indication_for_use: Pain and inflammation
  drug_class: NSAID
adverse_reactions:
- symptom_name: Stevens-Johnson syndrome
  onset_date: '2024-06-15'
  severity: Life-threatening
  outcome: Not Recovered
  intervention_required: true
- symptom_name: Diarrhea
  onset_date: '2024-06-15'
  severity: Moderate
  outcome: Unknown
  intervention_required: true
causality_assessment:
  assessment_conclusion: Probable
  dechallenge_rechallenge: Negative dechallenge
  naranjo_score: 8
reporting_facility: Foster, Cook and Patton Medical Center
reporter_type: Other Healthcare Professional
notes: Administration opportunity air. Politics consumer simply white serve most history.
  Their task method collection.
