<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2024-619
Date of Submission: 2024-11-03

This report was submitted by a Patient from Meadows-Russell Medical Center concerning patient ANON-PX-3900. The subject is a 69-year-old other with a significant medical history including type 2 diabetes, chronic kidney disease. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Ibuprofen administered via the Oral route at a dosage of 325mg, initiated on 2024-08-29 for Pain and inflammation and discontinued on 2024-10-27; Sertraline (SSRI) administered via the Intramuscular route at a dosage of 178mg, initiated on 2024-08-29 for Major depressive disorder and discontinued on 2024-10-27.

On approximately 2024-10-18, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Dizziness, Anaphylaxis, Headache, Diarrhea. The Dizziness was classified as Severe in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Fatal'. The Anaphylaxis was classified as Severe in severity. This necessitated clinical intervention. The current patient status regarding this symptom is 'Recovering'. The Headache was classified as Moderate in severity. This necessitated clinical intervention. The documented action was: Prescribed rock and advised even. The current patient status regarding this symptom is 'Fatal'. The Diarrhea was classified as Severe in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Unknown'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. A Naranjo score of 9 was calculated, The assessment concluded the relationship was 'Highly Probable'. Dechallenge/Rechallenge status was noted as: 'Negative dechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Agree when indeed short that environmental science.</data>
report_id: ADR-2024-619
report_date: '2024-11-03'
patient_details:
  patient_id: ANON-PX-3900
  gender: Other
  relevant_history:
  - type 2 diabetes
  - chronic kidney disease
  age_at_reaction: 69
suspected_drugs:
- drug_name: Ibuprofen
  dosage: 325mg
  route_of_administration: Oral
  start_date: '2024-08-29'
  indication_for_use: Pain and inflammation
  end_date: '2024-10-27'
- drug_name: Sertraline
  dosage: 178mg
  route_of_administration: Intramuscular
  start_date: '2024-08-29'
  indication_for_use: Major depressive disorder
  drug_class: SSRI
  end_date: '2024-10-27'
adverse_reactions:
- symptom_name: Dizziness
  onset_date: '2024-10-18'
  severity: Severe
  outcome: Fatal
  intervention_required: false
- symptom_name: Anaphylaxis
  onset_date: '2024-10-18'
  severity: Severe
  outcome: Recovering
  intervention_required: true
- symptom_name: Headache
  onset_date: '2024-10-18'
  severity: Moderate
  outcome: Fatal
  intervention_required: true
  intervention_details: Prescribed rock and advised even.
- symptom_name: Diarrhea
  onset_date: '2024-10-18'
  severity: Severe
  outcome: Unknown
  intervention_required: false
causality_assessment:
  assessment_conclusion: Highly Probable
  dechallenge_rechallenge: Negative dechallenge
  naranjo_score: 9
reporting_facility: Meadows-Russell Medical Center
reporter_type: Patient
notes: Agree when indeed short that environmental science.
