<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2024-616
Date of Submission: 2024-12-30

This report was submitted by a Patient from Castillo PLC Medical Center concerning patient ANON-PX-9162. The subject is an adult other with a significant medical history including atrial fibrillation, hypertension, migraines. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Amoxicillin (Penicillin antibiotic) administered via the Topical route at a dosage of 53mg, initiated on 2024-10-22 for Bacterial infection and discontinued on 2024-12-21.

On approximately 2024-12-05, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Pruritus, Stevens-Johnson syndrome, Headache. The Pruritus was classified as Life-threatening in severity. This necessitated clinical intervention. The documented action was: Prescribed without and advised follow. The current patient status regarding this symptom is 'Not Recovered'. The Stevens-Johnson syndrome was classified as Moderate in severity. This necessitated clinical intervention. The documented action was: Prescribed charge and advised activity. The current patient status regarding this symptom is 'Fatal'. The Headache was classified as Severe in severity. This necessitated clinical intervention. The documented action was: Prescribed thank and advised everything. The current patient status regarding this symptom is 'Not Recovered'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. A Naranjo score of 5 was calculated, The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Rechallenge not performed'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Kind institution effect individual mind senior body. Ok seek election fight sound also protect whom.</data>
report_id: ADR-2024-616
report_date: '2024-12-30'
patient_details:
  patient_id: ANON-PX-9162
  gender: Other
  relevant_history:
  - atrial fibrillation
  - hypertension
  - migraines
suspected_drugs:
- drug_name: Amoxicillin
  dosage: 53mg
  route_of_administration: Topical
  start_date: '2024-10-22'
  indication_for_use: Bacterial infection
  drug_class: Penicillin antibiotic
  end_date: '2024-12-21'
adverse_reactions:
- symptom_name: Pruritus
  onset_date: '2024-12-05'
  severity: Life-threatening
  outcome: Not Recovered
  intervention_required: true
  intervention_details: Prescribed without and advised follow.
- symptom_name: Stevens-Johnson syndrome
  onset_date: '2024-12-05'
  severity: Moderate
  outcome: Fatal
  intervention_required: true
  intervention_details: Prescribed charge and advised activity.
- symptom_name: Headache
  onset_date: '2024-12-05'
  severity: Severe
  outcome: Not Recovered
  intervention_required: true
  intervention_details: Prescribed thank and advised everything.
causality_assessment:
  assessment_conclusion: Probable
  dechallenge_rechallenge: Rechallenge not performed
  naranjo_score: 5
reporting_facility: Castillo PLC Medical Center
reporter_type: Patient
notes: Kind institution effect individual mind senior body. Ok seek election fight
  sound also protect whom.
