<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2024-471
Date of Submission: 2024-10-13

This report was submitted by a Other Healthcare Professional from Clark-Rose Medical Center concerning patient ANON-PX-2062. The subject is a 23-year-old other with a significant medical history including migraines, seasonal allergies, coronary artery disease, type 2 diabetes. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Warfarin administered via the Oral route at a dosage of 373mg, initiated on 2024-07-29 for Thromboembolism prevention and discontinued on 2024-09-15.

On approximately 2024-08-28, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Pruritus, Headache, Hepatotoxicity, Dizziness. The Pruritus was classified as Life-threatening in severity. This necessitated clinical intervention. The documented action was: Prescribed off and advised best. The current patient status regarding this symptom is 'Recovering'. The Headache was classified as Mild in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Unknown'. The Hepatotoxicity was classified as Mild in severity. This necessitated clinical intervention. The documented action was: Prescribed foreign and advised onto. The current patient status regarding this symptom is 'Unknown'. The Dizziness was classified as Mild in severity. This necessitated clinical intervention. The documented action was: Prescribed case and advised dark. The current patient status regarding this symptom is 'Not Recovered'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Negative dechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. 

</data>
report_id: ADR-2024-471
report_date: '2024-10-13'
patient_details:
  patient_id: ANON-PX-2062
  gender: Other
  relevant_history:
  - migraines
  - seasonal allergies
  - coronary artery disease
  - type 2 diabetes
  age_at_reaction: 23
suspected_drugs:
- drug_name: Warfarin
  dosage: 373mg
  route_of_administration: Oral
  start_date: '2024-07-29'
  indication_for_use: Thromboembolism prevention
  end_date: '2024-09-15'
adverse_reactions:
- symptom_name: Pruritus
  onset_date: '2024-08-28'
  severity: Life-threatening
  outcome: Recovering
  intervention_required: true
  intervention_details: Prescribed off and advised best.
- symptom_name: Headache
  onset_date: '2024-08-28'
  severity: Mild
  outcome: Unknown
  intervention_required: false
- symptom_name: Hepatotoxicity
  onset_date: '2024-08-28'
  severity: Mild
  outcome: Unknown
  intervention_required: true
  intervention_details: Prescribed foreign and advised onto.
- symptom_name: Dizziness
  onset_date: '2024-08-28'
  severity: Mild
  outcome: Not Recovered
  intervention_required: true
  intervention_details: Prescribed case and advised dark.
causality_assessment:
  assessment_conclusion: Probable
  dechallenge_rechallenge: Negative dechallenge
reporting_facility: Clark-Rose Medical Center
reporter_type: Other Healthcare Professional
