<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2025-744
Date of Submission: 2025-05-09

This report was submitted by a Nurse from Atkinson and Sons Medical Center concerning patient ANON-PX-5874. The subject is a 26-year-old female with a significant medical history including migraines, chronic kidney disease, hypertension, osteoarthritis. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Amoxicillin (Penicillin antibiotic) administered via the Oral route at a dosage of 118mg, initiated on 2025-04-30 for Bacterial infection and discontinued on 2025-05-07.

On approximately 2025-05-01, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Pruritus, Nausea, Maculopapular Rash, Hepatotoxicity. The Pruritus was classified as Moderate in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovering'. The Nausea was classified as Moderate in severity. This necessitated clinical intervention. The current patient status regarding this symptom is 'Not Recovered'. The Maculopapular Rash was classified as Moderate in severity. This necessitated clinical intervention. The documented action was: Prescribed agent and advised stop. The current patient status regarding this symptom is 'Recovered'. The Hepatotoxicity was classified as Moderate in severity. This necessitated clinical intervention. The current patient status regarding this symptom is 'Recovering'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Not applicable'. The on-site pharmacist concurred with the assessment during a routine case review. 

</data>
report_id: ADR-2025-744
report_date: '2025-05-09'
patient_details:
  patient_id: ANON-PX-5874
  gender: Female
  relevant_history:
  - migraines
  - chronic kidney disease
  - hypertension
  - osteoarthritis
  age_at_reaction: 26
suspected_drugs:
- drug_name: Amoxicillin
  dosage: 118mg
  route_of_administration: Oral
  start_date: '2025-04-30'
  indication_for_use: Bacterial infection
  drug_class: Penicillin antibiotic
  end_date: '2025-05-07'
adverse_reactions:
- symptom_name: Pruritus
  onset_date: '2025-05-01'
  severity: Moderate
  outcome: Recovering
  intervention_required: false
- symptom_name: Nausea
  onset_date: '2025-05-01'
  severity: Moderate
  outcome: Not Recovered
  intervention_required: true
- symptom_name: Maculopapular Rash
  onset_date: '2025-05-01'
  severity: Moderate
  outcome: Recovered
  intervention_required: true
  intervention_details: Prescribed agent and advised stop.
- symptom_name: Hepatotoxicity
  onset_date: '2025-05-01'
  severity: Moderate
  outcome: Recovering
  intervention_required: true
causality_assessment:
  assessment_conclusion: Probable
  dechallenge_rechallenge: Not applicable
reporting_facility: Atkinson and Sons Medical Center
reporter_type: Nurse
