<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2025-529
Date of Submission: 2025-03-26

This report was submitted by a Pharmacist from Thompson-Clark Medical Center concerning patient ANON-PX-7039. The subject is an adult female with a significant medical history including migraines, chronic kidney disease, anxiety. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Ibuprofen (NSAID) administered via the Intramuscular route at a dosage of 488mg, initiated on 2025-03-16 for Pain and inflammation with the course ongoing.

On approximately 2025-03-17, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Nausea, Stevens-Johnson syndrome. The Nausea was classified as Mild in severity. This necessitated clinical intervention. The documented action was: Prescribed only and advised walk. The current patient status regarding this symptom is 'Recovered'. The Stevens-Johnson syndrome was classified as Mild in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovered'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. A Naranjo score of 5 was calculated, The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Positive rechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. 

</data>
report_id: ADR-2025-529
report_date: '2025-03-26'
patient_details:
  patient_id: ANON-PX-7039
  gender: Female
  relevant_history:
  - migraines
  - chronic kidney disease
  - anxiety
suspected_drugs:
- drug_name: Ibuprofen
  dosage: 488mg
  route_of_administration: Intramuscular
  start_date: '2025-03-16'
  indication_for_use: Pain and inflammation
  drug_class: NSAID
adverse_reactions:
- symptom_name: Nausea
  onset_date: '2025-03-17'
  severity: Mild
  outcome: Recovered
  intervention_required: true
  intervention_details: Prescribed only and advised walk.
- symptom_name: Stevens-Johnson syndrome
  onset_date: '2025-03-17'
  severity: Mild
  outcome: Recovered
  intervention_required: false
causality_assessment:
  assessment_conclusion: Probable
  dechallenge_rechallenge: Positive rechallenge
  naranjo_score: 5
reporting_facility: Thompson-Clark Medical Center
reporter_type: Pharmacist
