<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2025-392
Date of Submission: 2025-02-13

This report was submitted by a Other Healthcare Professional from Harrell, Bell and Wong Medical Center concerning patient ANON-PX-9746. The subject is a 69-year-old male with a significant medical history including asthma, hypertension, coronary artery disease, anxiety. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Ibuprofen (NSAID) administered via the Intravenous route at a dosage of 460mg, initiated on 2025-01-02 for Pain and inflammation and discontinued on 2025-01-27; Gabapentin administered via the Intramuscular route at a dosage of 328mg, initiated on 2025-01-02 for Neuropathic pain and discontinued on 2025-01-27.

On approximately 2025-01-07, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Somnolence, Angioedema, Hepatotoxicity. The Somnolence was classified as Severe in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Unknown'. The Angioedema was classified as Life-threatening in severity. This necessitated clinical intervention. The documented action was: Prescribed garden and advised capital. The current patient status regarding this symptom is 'Recovered'. The Hepatotoxicity was classified as Moderate in severity. This necessitated clinical intervention. The documented action was: Prescribed TV and advised play. The current patient status regarding this symptom is 'Recovered'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Negative dechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Buy majority life history right claim. Marriage cold task simple. Mention miss on local lawyer.</data>
report_id: ADR-2025-392
report_date: '2025-02-13'
patient_details:
  patient_id: ANON-PX-9746
  gender: Male
  relevant_history:
  - asthma
  - hypertension
  - coronary artery disease
  - anxiety
  age_at_reaction: 69
suspected_drugs:
- drug_name: Ibuprofen
  dosage: 460mg
  route_of_administration: Intravenous
  start_date: '2025-01-02'
  indication_for_use: Pain and inflammation
  drug_class: NSAID
  end_date: '2025-01-27'
- drug_name: Gabapentin
  dosage: 328mg
  route_of_administration: Intramuscular
  start_date: '2025-01-02'
  indication_for_use: Neuropathic pain
  end_date: '2025-01-27'
adverse_reactions:
- symptom_name: Somnolence
  onset_date: '2025-01-07'
  severity: Severe
  outcome: Unknown
  intervention_required: false
- symptom_name: Angioedema
  onset_date: '2025-01-07'
  severity: Life-threatening
  outcome: Recovered
  intervention_required: true
  intervention_details: Prescribed garden and advised capital.
- symptom_name: Hepatotoxicity
  onset_date: '2025-01-07'
  severity: Moderate
  outcome: Recovered
  intervention_required: true
  intervention_details: Prescribed TV and advised play.
causality_assessment:
  assessment_conclusion: Probable
  dechallenge_rechallenge: Negative dechallenge
reporting_facility: Harrell, Bell and Wong Medical Center
reporter_type: Other Healthcare Professional
notes: Buy majority life history right claim. Marriage cold task simple. Mention miss
  on local lawyer.
