<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2024-630
Date of Submission: 2024-11-16

This report was submitted by a Pharmacist from Rodriguez, Webster and Dunn Medical Center concerning patient ANON-PX-3000. The subject is a 80-year-old female with a significant medical history including osteoarthritis, hypertension. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Metformin administered via the Subcutaneous route at a dosage of 408mg, initiated on 2024-09-08 for Type 2 diabetes and discontinued on 2024-11-10; Amoxicillin (Penicillin antibiotic) administered via the Topical route at a dosage of 444mg, initiated on 2024-09-08 for Bacterial infection and discontinued on 2024-11-10.

On approximately 2024-11-02, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Vomiting, Angioedema. The Vomiting was classified as Moderate in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovered'. The Angioedema was classified as Severe in severity. This necessitated clinical intervention. The documented action was: Prescribed accept and advised good. The current patient status regarding this symptom is 'Not Recovered'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Rechallenge not performed'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Name blue learn collection. Fish everything relate her protect himself interesting nothing. Quality my pull pretty.</data>
report_id: ADR-2024-630
report_date: '2024-11-16'
patient_details:
  patient_id: ANON-PX-3000
  gender: Female
  relevant_history:
  - osteoarthritis
  - hypertension
  age_at_reaction: 80
suspected_drugs:
- drug_name: Metformin
  dosage: 408mg
  route_of_administration: Subcutaneous
  start_date: '2024-09-08'
  indication_for_use: Type 2 diabetes
  end_date: '2024-11-10'
- drug_name: Amoxicillin
  dosage: 444mg
  route_of_administration: Topical
  start_date: '2024-09-08'
  indication_for_use: Bacterial infection
  drug_class: Penicillin antibiotic
  end_date: '2024-11-10'
adverse_reactions:
- symptom_name: Vomiting
  onset_date: '2024-11-02'
  severity: Moderate
  outcome: Recovered
  intervention_required: false
- symptom_name: Angioedema
  onset_date: '2024-11-02'
  severity: Severe
  outcome: Not Recovered
  intervention_required: true
  intervention_details: Prescribed accept and advised good.
causality_assessment:
  assessment_conclusion: Probable
  dechallenge_rechallenge: Rechallenge not performed
reporting_facility: Rodriguez, Webster and Dunn Medical Center
reporter_type: Pharmacist
notes: Name blue learn collection. Fish everything relate her protect himself interesting
  nothing. Quality my pull pretty.
