<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2024-878
Date of Submission: 2024-08-18

This report was submitted by a Other Healthcare Professional from Miller-Rojas Medical Center concerning patient ANON-PX-1421. The subject is an adult other with a significant medical history including hypertension, coronary artery disease. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Sertraline administered via the Intravenous route at a dosage of 371mg, initiated on 2024-07-06 for Major depressive disorder with the course ongoing.

On approximately 2024-07-21, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Stevens-Johnson syndrome, Somnolence. The Stevens-Johnson syndrome was classified as Mild in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Fatal'. The Somnolence was classified as Severe in severity. This necessitated clinical intervention. The documented action was: Prescribed middle and advised draw. The current patient status regarding this symptom is 'Recovered'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Positive dechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Performance beautiful per white brother quite simply though.</data>
report_id: ADR-2024-878
report_date: '2024-08-18'
patient_details:
  patient_id: ANON-PX-1421
  gender: Other
  relevant_history:
  - hypertension
  - coronary artery disease
suspected_drugs:
- drug_name: Sertraline
  dosage: 371mg
  route_of_administration: Intravenous
  start_date: '2024-07-06'
  indication_for_use: Major depressive disorder
adverse_reactions:
- symptom_name: Stevens-Johnson syndrome
  onset_date: '2024-07-21'
  severity: Mild
  outcome: Fatal
  intervention_required: false
- symptom_name: Somnolence
  onset_date: '2024-07-21'
  severity: Severe
  outcome: Recovered
  intervention_required: true
  intervention_details: Prescribed middle and advised draw.
causality_assessment:
  assessment_conclusion: Probable
  dechallenge_rechallenge: Positive dechallenge
reporting_facility: Miller-Rojas Medical Center
reporter_type: Other Healthcare Professional
notes: Performance beautiful per white brother quite simply though.
