<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2024-899
Date of Submission: 2024-11-22

This report was submitted by a Patient from Kemp Inc Medical Center concerning patient ANON-PX-3758. The subject is a 66-year-old other with a significant medical history including hypertension, atrial fibrillation, chronic kidney disease. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Lisinopril administered via the Subcutaneous route at a dosage of 21mg, initiated on 2024-09-25 for Hypertension and discontinued on 2024-11-10.

On approximately 2024-11-02, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Hepatotoxicity, Nausea, Stevens-Johnson syndrome. The Hepatotoxicity was classified as Life-threatening in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovered'. The Nausea was classified as Life-threatening in severity. This necessitated clinical intervention. The current patient status regarding this symptom is 'Recovered'. The Stevens-Johnson syndrome was classified as Severe in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovering'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Positive dechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Long forget meeting pretty century. Capital sing mission blood half rise pass.</data>
report_id: ADR-2024-899
report_date: '2024-11-22'
patient_details:
  patient_id: ANON-PX-3758
  gender: Other
  relevant_history:
  - hypertension
  - atrial fibrillation
  - chronic kidney disease
  age_at_reaction: 66
suspected_drugs:
- drug_name: Lisinopril
  dosage: 21mg
  route_of_administration: Subcutaneous
  start_date: '2024-09-25'
  indication_for_use: Hypertension
  end_date: '2024-11-10'
adverse_reactions:
- symptom_name: Hepatotoxicity
  onset_date: '2024-11-02'
  severity: Life-threatening
  outcome: Recovered
  intervention_required: false
- symptom_name: Nausea
  onset_date: '2024-11-02'
  severity: Life-threatening
  outcome: Recovered
  intervention_required: true
- symptom_name: Stevens-Johnson syndrome
  onset_date: '2024-11-02'
  severity: Severe
  outcome: Recovering
  intervention_required: false
causality_assessment:
  assessment_conclusion: Probable
  dechallenge_rechallenge: Positive dechallenge
reporting_facility: Kemp Inc Medical Center
reporter_type: Patient
notes: Long forget meeting pretty century. Capital sing mission blood half rise pass.
