<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2024-598
Date of Submission: 2024-10-22

This report was submitted by a Physician from Morgan, Flores and Henry Medical Center concerning patient ANON-PX-4071. The subject is a 29-year-old other with a significant medical history including type 2 diabetes, seasonal allergies, asthma, migraines. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Ibuprofen (NSAID) administered via the Intravenous route at a dosage of 142mg, initiated on 2024-09-18 for Pain and inflammation and discontinued on 2024-10-18; Levothyroxine (Thyroid hormone) administered via the Oral route at a dosage of 478mg, initiated on 2024-09-18 for Hypothyroidism and discontinued on 2024-10-18.

On approximately 2024-10-10, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Anaphylaxis, Diarrhea. The Anaphylaxis was classified as Severe in severity. This necessitated clinical intervention. The documented action was: Prescribed many and advised drive. The current patient status regarding this symptom is 'Not Recovered'. The Diarrhea was classified as Moderate in severity. This necessitated clinical intervention. The documented action was: Prescribed yet and advised produce. The current patient status regarding this symptom is 'Recovered'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. A Naranjo score of 9 was calculated, The assessment concluded the relationship was 'Highly Probable'. Dechallenge/Rechallenge status was noted as: 'Negative dechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. 

</data>
report_id: ADR-2024-598
report_date: '2024-10-22'
patient_details:
  patient_id: ANON-PX-4071
  gender: Other
  relevant_history:
  - type 2 diabetes
  - seasonal allergies
  - asthma
  - migraines
  age_at_reaction: 29
suspected_drugs:
- drug_name: Ibuprofen
  dosage: 142mg
  route_of_administration: Intravenous
  start_date: '2024-09-18'
  indication_for_use: Pain and inflammation
  drug_class: NSAID
  end_date: '2024-10-18'
- drug_name: Levothyroxine
  dosage: 478mg
  route_of_administration: Oral
  start_date: '2024-09-18'
  indication_for_use: Hypothyroidism
  drug_class: Thyroid hormone
  end_date: '2024-10-18'
adverse_reactions:
- symptom_name: Anaphylaxis
  onset_date: '2024-10-10'
  severity: Severe
  outcome: Not Recovered
  intervention_required: true
  intervention_details: Prescribed many and advised drive.
- symptom_name: Diarrhea
  onset_date: '2024-10-10'
  severity: Moderate
  outcome: Recovered
  intervention_required: true
  intervention_details: Prescribed yet and advised produce.
causality_assessment:
  assessment_conclusion: Highly Probable
  dechallenge_rechallenge: Negative dechallenge
  naranjo_score: 9
reporting_facility: Morgan, Flores and Henry Medical Center
reporter_type: Physician
