<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2025-493
Date of Submission: 2025-01-26

This report was submitted by a Other Healthcare Professional from Ross, Spencer and Ramirez Medical Center concerning patient ANON-PX-2218. The subject is an adult female with a significant medical history including osteoarthritis, atrial fibrillation, coronary artery disease, asthma. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Omeprazole (Proton-pump inhibitor) administered via the Intravenous route at a dosage of 448mg, initiated on 2025-01-06 for Gastroesophageal reflux disease with the course ongoing; Lisinopril (ACE inhibitor) administered via the Intravenous route at a dosage of 96mg, initiated on 2025-01-06 for Hypertension with the course ongoing.

On approximately 2025-01-14, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Dizziness, Headache. The Dizziness was classified as Life-threatening in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Unknown'. The Headache was classified as Mild in severity. This necessitated clinical intervention. The documented action was: Prescribed course and advised as. The current patient status regarding this symptom is 'Recovering'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Not applicable'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Hospital rather four yard father sort.</data>
report_id: ADR-2025-493
report_date: '2025-01-26'
patient_details:
  patient_id: ANON-PX-2218
  gender: Female
  relevant_history:
  - osteoarthritis
  - atrial fibrillation
  - coronary artery disease
  - asthma
suspected_drugs:
- drug_name: Omeprazole
  dosage: 448mg
  route_of_administration: Intravenous
  start_date: '2025-01-06'
  indication_for_use: Gastroesophageal reflux disease
  drug_class: Proton-pump inhibitor
- drug_name: Lisinopril
  dosage: 96mg
  route_of_administration: Intravenous
  start_date: '2025-01-06'
  indication_for_use: Hypertension
  drug_class: ACE inhibitor
adverse_reactions:
- symptom_name: Dizziness
  onset_date: '2025-01-14'
  severity: Life-threatening
  outcome: Unknown
  intervention_required: false
- symptom_name: Headache
  onset_date: '2025-01-14'
  severity: Mild
  outcome: Recovering
  intervention_required: true
  intervention_details: Prescribed course and advised as.
causality_assessment:
  assessment_conclusion: Probable
  dechallenge_rechallenge: Not applicable
reporting_facility: Ross, Spencer and Ramirez Medical Center
reporter_type: Other Healthcare Professional
notes: Hospital rather four yard father sort.
