<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2024-848
Date of Submission: 2024-10-13

This report was submitted by a Other Healthcare Professional from White-Harmon Medical Center concerning patient ANON-PX-3377. The subject is a 34-year-old other with a significant medical history including coronary artery disease, anxiety. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Sertraline administered via the Oral route at a dosage of 155mg, initiated on 2024-08-20 for Major depressive disorder and discontinued on 2024-09-17.

On approximately 2024-08-23, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Somnolence, Angioedema, Stevens-Johnson syndrome, Nausea. The Somnolence was classified as Severe in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovered'. The Angioedema was classified as Life-threatening in severity. This necessitated clinical intervention. The documented action was: Prescribed role and advised member. The current patient status regarding this symptom is 'Not Recovered'. The Stevens-Johnson syndrome was classified as Moderate in severity. This necessitated clinical intervention. The current patient status regarding this symptom is 'Unknown'. The Nausea was classified as Mild in severity. This necessitated clinical intervention. The documented action was: Prescribed gas and advised you. The current patient status regarding this symptom is 'Unknown'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. A Naranjo score of 1 was calculated, The assessment concluded the relationship was 'Possible'. Dechallenge/Rechallenge status was noted as: 'Positive dechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Mention court degree as western boy. Whole score public institution prevent fall. Job skin manager admit street. Wear very reduce.</data>
report_id: ADR-2024-848
report_date: '2024-10-13'
patient_details:
  patient_id: ANON-PX-3377
  gender: Other
  relevant_history:
  - coronary artery disease
  - anxiety
  age_at_reaction: 34
suspected_drugs:
- drug_name: Sertraline
  dosage: 155mg
  route_of_administration: Oral
  start_date: '2024-08-20'
  indication_for_use: Major depressive disorder
  end_date: '2024-09-17'
adverse_reactions:
- symptom_name: Somnolence
  onset_date: '2024-08-23'
  severity: Severe
  outcome: Recovered
  intervention_required: false
- symptom_name: Angioedema
  onset_date: '2024-08-23'
  severity: Life-threatening
  outcome: Not Recovered
  intervention_required: true
  intervention_details: Prescribed role and advised member.
- symptom_name: Stevens-Johnson syndrome
  onset_date: '2024-08-23'
  severity: Moderate
  outcome: Unknown
  intervention_required: true
- symptom_name: Nausea
  onset_date: '2024-08-23'
  severity: Mild
  outcome: Unknown
  intervention_required: true
  intervention_details: Prescribed gas and advised you.
causality_assessment:
  assessment_conclusion: Possible
  dechallenge_rechallenge: Positive dechallenge
  naranjo_score: 1
reporting_facility: White-Harmon Medical Center
reporter_type: Other Healthcare Professional
notes: Mention court degree as western boy. Whole score public institution prevent
  fall. Job skin manager admit street. Wear very reduce.
