<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2024-182
Date of Submission: 2024-10-30

This report was submitted by a Patient from Shaw LLC Medical Center concerning patient ANON-PX-6317. The subject is a 46-year-old other with a significant medical history including asthma, atrial fibrillation. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Levothyroxine (Thyroid hormone) administered via the Topical route at a dosage of 33mg, initiated on 2024-10-19 for Hypothyroidism and discontinued on 2024-10-29; Lisinopril (ACE inhibitor) administered via the Subcutaneous route at a dosage of 191mg, initiated on 2024-10-19 for Hypertension and discontinued on 2024-10-29.

On approximately 2024-10-28, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Somnolence, Vomiting, Diarrhea, Dizziness, Stevens-Johnson syndrome. The Somnolence was classified as Life-threatening in severity. This necessitated clinical intervention. The current patient status regarding this symptom is 'Unknown'. The Vomiting was classified as Life-threatening in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovered'. The Diarrhea was classified as Moderate in severity. This necessitated clinical intervention. The documented action was: Prescribed into and advised adult. The current patient status regarding this symptom is 'Recovering'. The Dizziness was classified as Moderate in severity. This necessitated clinical intervention. The documented action was: Prescribed happen and advised daughter. The current patient status regarding this symptom is 'Not Recovered'. The Stevens-Johnson syndrome was classified as Moderate in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Unknown'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. A Naranjo score of 7 was calculated, The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Positive dechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Decade learn Democrat student its. Chair analysis group culture course.</data>
report_id: ADR-2024-182
report_date: '2024-10-30'
patient_details:
  patient_id: ANON-PX-6317
  gender: Other
  relevant_history:
  - asthma
  - atrial fibrillation
  age_at_reaction: 46
suspected_drugs:
- drug_name: Levothyroxine
  dosage: 33mg
  route_of_administration: Topical
  start_date: '2024-10-19'
  indication_for_use: Hypothyroidism
  drug_class: Thyroid hormone
  end_date: '2024-10-29'
- drug_name: Lisinopril
  dosage: 191mg
  route_of_administration: Subcutaneous
  start_date: '2024-10-19'
  indication_for_use: Hypertension
  drug_class: ACE inhibitor
  end_date: '2024-10-29'
adverse_reactions:
- symptom_name: Somnolence
  onset_date: '2024-10-28'
  severity: Life-threatening
  outcome: Unknown
  intervention_required: true
- symptom_name: Vomiting
  onset_date: '2024-10-28'
  severity: Life-threatening
  outcome: Recovered
  intervention_required: false
- symptom_name: Diarrhea
  onset_date: '2024-10-28'
  severity: Moderate
  outcome: Recovering
  intervention_required: true
  intervention_details: Prescribed into and advised adult.
- symptom_name: Dizziness
  onset_date: '2024-10-28'
  severity: Moderate
  outcome: Not Recovered
  intervention_required: true
  intervention_details: Prescribed happen and advised daughter.
- symptom_name: Stevens-Johnson syndrome
  onset_date: '2024-10-28'
  severity: Moderate
  outcome: Unknown
  intervention_required: false
causality_assessment:
  assessment_conclusion: Probable
  dechallenge_rechallenge: Positive dechallenge
  naranjo_score: 7
reporting_facility: Shaw LLC Medical Center
reporter_type: Patient
notes: Decade learn Democrat student its. Chair analysis group culture course.
