<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2024-914
Date of Submission: 2024-12-04

This report was submitted by a Patient from Garza-Peterson Medical Center concerning patient ANON-PX-7285. The subject is a 24-year-old female with a significant medical history including hypertension, migraines, coronary artery disease. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Omeprazole (Proton-pump inhibitor) administered via the Oral route at a dosage of 407mg, initiated on 2024-11-11 for Gastroesophageal reflux disease and discontinued on 2024-11-29; Warfarin (Anticoagulant) administered via the Intramuscular route at a dosage of 455mg, initiated on 2024-11-11 for Thromboembolism prevention and discontinued on 2024-11-29.

On approximately 2024-11-29, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Nausea, Diarrhea, Somnolence, Stevens-Johnson syndrome. The Nausea was classified as Moderate in severity. This necessitated clinical intervention. The documented action was: Prescribed project and advised never. The current patient status regarding this symptom is 'Unknown'. The Diarrhea was classified as Moderate in severity. This necessitated clinical intervention. The documented action was: Prescribed college and advised source. The current patient status regarding this symptom is 'Recovering'. The Somnolence was classified as Severe in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Not Recovered'. The Stevens-Johnson syndrome was classified as Moderate in severity. This necessitated clinical intervention. The current patient status regarding this symptom is 'Not Recovered'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. A Naranjo score of 1 was calculated, The assessment concluded the relationship was 'Possible'. Dechallenge/Rechallenge status was noted as: 'Positive dechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Establish mouth soon special entire. Worker specific wear.</data>
report_id: ADR-2024-914
report_date: '2024-12-04'
patient_details:
  patient_id: ANON-PX-7285
  gender: Female
  relevant_history:
  - hypertension
  - migraines
  - coronary artery disease
  age_at_reaction: 24
suspected_drugs:
- drug_name: Omeprazole
  dosage: 407mg
  route_of_administration: Oral
  start_date: '2024-11-11'
  indication_for_use: Gastroesophageal reflux disease
  drug_class: Proton-pump inhibitor
  end_date: '2024-11-29'
- drug_name: Warfarin
  dosage: 455mg
  route_of_administration: Intramuscular
  start_date: '2024-11-11'
  indication_for_use: Thromboembolism prevention
  drug_class: Anticoagulant
  end_date: '2024-11-29'
adverse_reactions:
- symptom_name: Nausea
  onset_date: '2024-11-29'
  severity: Moderate
  outcome: Unknown
  intervention_required: true
  intervention_details: Prescribed project and advised never.
- symptom_name: Diarrhea
  onset_date: '2024-11-29'
  severity: Moderate
  outcome: Recovering
  intervention_required: true
  intervention_details: Prescribed college and advised source.
- symptom_name: Somnolence
  onset_date: '2024-11-29'
  severity: Severe
  outcome: Not Recovered
  intervention_required: false
- symptom_name: Stevens-Johnson syndrome
  onset_date: '2024-11-29'
  severity: Moderate
  outcome: Not Recovered
  intervention_required: true
causality_assessment:
  assessment_conclusion: Possible
  dechallenge_rechallenge: Positive dechallenge
  naranjo_score: 1
reporting_facility: Garza-Peterson Medical Center
reporter_type: Patient
notes: Establish mouth soon special entire. Worker specific wear.
