<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2025-746
Date of Submission: 2025-04-04

This report was submitted by a Nurse from Aguilar LLC Medical Center concerning patient ANON-PX-1430. The subject is an adult other with a significant medical history including atrial fibrillation, hypertension, type 2 diabetes. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Omeprazole (Proton-pump inhibitor) administered via the Intramuscular route at a dosage of 247mg, initiated on 2025-01-30 for Gastroesophageal reflux disease and discontinued on 2025-02-18.

On approximately 2025-02-09, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Diarrhea, Somnolence, Angioedema, Anaphylaxis. The Diarrhea was classified as Mild in severity. This necessitated clinical intervention. The documented action was: Prescribed along and advised population. The current patient status regarding this symptom is 'Not Recovered'. The Somnolence was classified as Life-threatening in severity. This necessitated clinical intervention. The current patient status regarding this symptom is 'Unknown'. The Angioedema was classified as Severe in severity. This necessitated clinical intervention. The current patient status regarding this symptom is 'Recovered'. The Anaphylaxis was classified as Moderate in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovered'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. A Naranjo score of 2 was calculated, The assessment concluded the relationship was 'Possible'. Dechallenge/Rechallenge status was noted as: 'Rechallenge not performed'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Tree evidence term. Partner American song choose song serve.</data>
report_id: ADR-2025-746
report_date: '2025-04-04'
patient_details:
  patient_id: ANON-PX-1430
  gender: Other
  relevant_history:
  - atrial fibrillation
  - hypertension
  - type 2 diabetes
suspected_drugs:
- drug_name: Omeprazole
  dosage: 247mg
  route_of_administration: Intramuscular
  start_date: '2025-01-30'
  indication_for_use: Gastroesophageal reflux disease
  drug_class: Proton-pump inhibitor
  end_date: '2025-02-18'
adverse_reactions:
- symptom_name: Diarrhea
  onset_date: '2025-02-09'
  severity: Mild
  outcome: Not Recovered
  intervention_required: true
  intervention_details: Prescribed along and advised population.
- symptom_name: Somnolence
  onset_date: '2025-02-09'
  severity: Life-threatening
  outcome: Unknown
  intervention_required: true
- symptom_name: Angioedema
  onset_date: '2025-02-09'
  severity: Severe
  outcome: Recovered
  intervention_required: true
- symptom_name: Anaphylaxis
  onset_date: '2025-02-09'
  severity: Moderate
  outcome: Recovered
  intervention_required: false
causality_assessment:
  assessment_conclusion: Possible
  dechallenge_rechallenge: Rechallenge not performed
  naranjo_score: 2
reporting_facility: Aguilar LLC Medical Center
reporter_type: Nurse
notes: Tree evidence term. Partner American song choose song serve.
