<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2024-322
Date of Submission: 2024-09-17

This report was submitted by a Physician from Gonzalez, Gomez and Thompson Medical Center concerning patient ANON-PX-8137. The subject is a 40-year-old other with a significant medical history including hypertension, migraines. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Ibuprofen administered via the Intramuscular route at a dosage of 331mg, initiated on 2024-07-02 for Pain and inflammation with the course ongoing.

On approximately 2024-07-14, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Pruritus, Somnolence, Headache. The Pruritus was classified as Moderate in severity. This necessitated clinical intervention. The documented action was: Prescribed state and advised bank. The current patient status regarding this symptom is 'Not Recovered'. The Somnolence was classified as Moderate in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Fatal'. The Headache was classified as Life-threatening in severity. This necessitated clinical intervention. The documented action was: Prescribed up and advised phone. The current patient status regarding this symptom is 'Recovering'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Positive dechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. 

</data>
report_id: ADR-2024-322
report_date: '2024-09-17'
patient_details:
  patient_id: ANON-PX-8137
  gender: Other
  relevant_history:
  - hypertension
  - migraines
  age_at_reaction: 40
suspected_drugs:
- drug_name: Ibuprofen
  dosage: 331mg
  route_of_administration: Intramuscular
  start_date: '2024-07-02'
  indication_for_use: Pain and inflammation
adverse_reactions:
- symptom_name: Pruritus
  onset_date: '2024-07-14'
  severity: Moderate
  outcome: Not Recovered
  intervention_required: true
  intervention_details: Prescribed state and advised bank.
- symptom_name: Somnolence
  onset_date: '2024-07-14'
  severity: Moderate
  outcome: Fatal
  intervention_required: false
- symptom_name: Headache
  onset_date: '2024-07-14'
  severity: Life-threatening
  outcome: Recovering
  intervention_required: true
  intervention_details: Prescribed up and advised phone.
causality_assessment:
  assessment_conclusion: Probable
  dechallenge_rechallenge: Positive dechallenge
reporting_facility: Gonzalez, Gomez and Thompson Medical Center
reporter_type: Physician
