<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2025-858
Date of Submission: 2025-03-10

This report was submitted by a Nurse from Brooks Ltd Medical Center concerning patient ANON-PX-9576. The subject is a 77-year-old male with a significant medical history including chronic kidney disease, type 2 diabetes, coronary artery disease. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Atorvastatin (Statin) administered via the Intravenous route at a dosage of 161mg, initiated on 2025-02-27 for Hypercholesterolemia and discontinued on 2025-03-04; Warfarin (Anticoagulant) administered via the Oral route at a dosage of 53mg, initiated on 2025-02-27 for Thromboembolism prevention and discontinued on 2025-03-04.

On approximately 2025-03-03, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Somnolence, Anaphylaxis, Angioedema. The Somnolence was classified as Life-threatening in severity. This necessitated clinical intervention. The current patient status regarding this symptom is 'Not Recovered'. The Anaphylaxis was classified as Mild in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Unknown'. The Angioedema was classified as Moderate in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Unknown'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Negative dechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Hair pretty everybody forget. Less guess drive newspaper. Fear edge table degree this light Mrs.</data>
report_id: ADR-2025-858
report_date: '2025-03-10'
patient_details:
  patient_id: ANON-PX-9576
  gender: Male
  relevant_history:
  - chronic kidney disease
  - type 2 diabetes
  - coronary artery disease
  age_at_reaction: 77
suspected_drugs:
- drug_name: Atorvastatin
  dosage: 161mg
  route_of_administration: Intravenous
  start_date: '2025-02-27'
  indication_for_use: Hypercholesterolemia
  drug_class: Statin
  end_date: '2025-03-04'
- drug_name: Warfarin
  dosage: 53mg
  route_of_administration: Oral
  start_date: '2025-02-27'
  indication_for_use: Thromboembolism prevention
  drug_class: Anticoagulant
  end_date: '2025-03-04'
adverse_reactions:
- symptom_name: Somnolence
  onset_date: '2025-03-03'
  severity: Life-threatening
  outcome: Not Recovered
  intervention_required: true
- symptom_name: Anaphylaxis
  onset_date: '2025-03-03'
  severity: Mild
  outcome: Unknown
  intervention_required: false
- symptom_name: Angioedema
  onset_date: '2025-03-03'
  severity: Moderate
  outcome: Unknown
  intervention_required: false
causality_assessment:
  assessment_conclusion: Probable
  dechallenge_rechallenge: Negative dechallenge
reporting_facility: Brooks Ltd Medical Center
reporter_type: Nurse
notes: Hair pretty everybody forget. Less guess drive newspaper. Fear edge table degree
  this light Mrs.
