<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2025-948
Date of Submission: 2025-02-17

This report was submitted by a Physician from Clements, Davis and Jones Medical Center concerning patient ANON-PX-4244. The subject is an adult other with a significant medical history including seasonal allergies, hypertension. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Lisinopril (ACE inhibitor) administered via the Subcutaneous route at a dosage of 63mg, initiated on 2025-01-29 for Hypertension with the course ongoing.

On approximately 2025-02-02, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Nausea, Somnolence, Headache. The Nausea was classified as Mild in severity. This necessitated clinical intervention. The documented action was: Prescribed stay and advised economic. The current patient status regarding this symptom is 'Recovering'. The Somnolence was classified as Mild in severity. This necessitated clinical intervention. The documented action was: Prescribed off and advised suggest. The current patient status regarding this symptom is 'Not Recovered'. The Headache was classified as Life-threatening in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovering'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. A Naranjo score of 9 was calculated, The assessment concluded the relationship was 'Highly Probable'. Dechallenge/Rechallenge status was noted as: 'Negative dechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. 

</data>
report_id: ADR-2025-948
report_date: '2025-02-17'
patient_details:
  patient_id: ANON-PX-4244
  gender: Other
  relevant_history:
  - seasonal allergies
  - hypertension
suspected_drugs:
- drug_name: Lisinopril
  dosage: 63mg
  route_of_administration: Subcutaneous
  start_date: '2025-01-29'
  indication_for_use: Hypertension
  drug_class: ACE inhibitor
adverse_reactions:
- symptom_name: Nausea
  onset_date: '2025-02-02'
  severity: Mild
  outcome: Recovering
  intervention_required: true
  intervention_details: Prescribed stay and advised economic.
- symptom_name: Somnolence
  onset_date: '2025-02-02'
  severity: Mild
  outcome: Not Recovered
  intervention_required: true
  intervention_details: Prescribed off and advised suggest.
- symptom_name: Headache
  onset_date: '2025-02-02'
  severity: Life-threatening
  outcome: Recovering
  intervention_required: false
causality_assessment:
  assessment_conclusion: Highly Probable
  dechallenge_rechallenge: Negative dechallenge
  naranjo_score: 9
reporting_facility: Clements, Davis and Jones Medical Center
reporter_type: Physician
