<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2024-727
Date of Submission: 2024-09-04

This report was submitted by a Other Healthcare Professional from Bean-Garcia Medical Center concerning patient ANON-PX-6651. The subject is a 74-year-old male with a significant medical history including type 2 diabetes, seasonal allergies, coronary artery disease, hypertension. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Levothyroxine administered via the Intramuscular route at a dosage of 138mg, initiated on 2024-08-21 for Hypothyroidism and discontinued on 2024-08-30; Omeprazole (Proton-pump inhibitor) administered via the Intramuscular route at a dosage of 239mg, initiated on 2024-08-21 for Gastroesophageal reflux disease and discontinued on 2024-08-30.

On approximately 2024-08-22, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Vomiting, Somnolence. The Vomiting was classified as Life-threatening in severity. This necessitated clinical intervention. The documented action was: Prescribed street and advised yeah. The current patient status regarding this symptom is 'Unknown'. The Somnolence was classified as Moderate in severity. This necessitated clinical intervention. The documented action was: Prescribed commercial and advised sport. The current patient status regarding this symptom is 'Recovering'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. A Naranjo score of 8 was calculated, The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Not applicable'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Never employee west thought now much. Industry road idea life.</data>
report_id: ADR-2024-727
report_date: '2024-09-04'
patient_details:
  patient_id: ANON-PX-6651
  gender: Male
  relevant_history:
  - type 2 diabetes
  - seasonal allergies
  - coronary artery disease
  - hypertension
  age_at_reaction: 74
suspected_drugs:
- drug_name: Levothyroxine
  dosage: 138mg
  route_of_administration: Intramuscular
  start_date: '2024-08-21'
  indication_for_use: Hypothyroidism
  end_date: '2024-08-30'
- drug_name: Omeprazole
  dosage: 239mg
  route_of_administration: Intramuscular
  start_date: '2024-08-21'
  indication_for_use: Gastroesophageal reflux disease
  drug_class: Proton-pump inhibitor
  end_date: '2024-08-30'
adverse_reactions:
- symptom_name: Vomiting
  onset_date: '2024-08-22'
  severity: Life-threatening
  outcome: Unknown
  intervention_required: true
  intervention_details: Prescribed street and advised yeah.
- symptom_name: Somnolence
  onset_date: '2024-08-22'
  severity: Moderate
  outcome: Recovering
  intervention_required: true
  intervention_details: Prescribed commercial and advised sport.
causality_assessment:
  assessment_conclusion: Probable
  dechallenge_rechallenge: Not applicable
  naranjo_score: 8
reporting_facility: Bean-Garcia Medical Center
reporter_type: Other Healthcare Professional
notes: Never employee west thought now much. Industry road idea life.
