<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2025-745
Date of Submission: 2025-03-09

This report was submitted by a Physician from Mcgee-Fernandez Medical Center concerning patient ANON-PX-7819. The subject is an adult male with a significant medical history including migraines, hypertension, seasonal allergies. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Atorvastatin (Statin) administered via the Subcutaneous route at a dosage of 206mg, initiated on 2025-02-23 for Hypercholesterolemia with the course ongoing.

On approximately 2025-02-26, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Anaphylaxis, Stevens-Johnson syndrome, Headache. The Anaphylaxis was classified as Severe in severity. This necessitated clinical intervention. The documented action was: Prescribed benefit and advised poor. The current patient status regarding this symptom is 'Fatal'. The Stevens-Johnson syndrome was classified as Severe in severity. This necessitated clinical intervention. The documented action was: Prescribed really and advised five. The current patient status regarding this symptom is 'Not Recovered'. The Headache was classified as Moderate in severity. This necessitated clinical intervention. The documented action was: Prescribed little and advised cut. The current patient status regarding this symptom is 'Unknown'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. A Naranjo score of 9 was calculated, The assessment concluded the relationship was 'Highly Probable'. Dechallenge/Rechallenge status was noted as: 'Positive rechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Once law crime challenge one by certain. News sound grow prepare my. Radio different care easy security building.</data>
report_id: ADR-2025-745
report_date: '2025-03-09'
patient_details:
  patient_id: ANON-PX-7819
  gender: Male
  relevant_history:
  - migraines
  - hypertension
  - seasonal allergies
suspected_drugs:
- drug_name: Atorvastatin
  dosage: 206mg
  route_of_administration: Subcutaneous
  start_date: '2025-02-23'
  indication_for_use: Hypercholesterolemia
  drug_class: Statin
adverse_reactions:
- symptom_name: Anaphylaxis
  onset_date: '2025-02-26'
  severity: Severe
  outcome: Fatal
  intervention_required: true
  intervention_details: Prescribed benefit and advised poor.
- symptom_name: Stevens-Johnson syndrome
  onset_date: '2025-02-26'
  severity: Severe
  outcome: Not Recovered
  intervention_required: true
  intervention_details: Prescribed really and advised five.
- symptom_name: Headache
  onset_date: '2025-02-26'
  severity: Moderate
  outcome: Unknown
  intervention_required: true
  intervention_details: Prescribed little and advised cut.
causality_assessment:
  assessment_conclusion: Highly Probable
  dechallenge_rechallenge: Positive rechallenge
  naranjo_score: 9
reporting_facility: Mcgee-Fernandez Medical Center
reporter_type: Physician
notes: Once law crime challenge one by certain. News sound grow prepare my. Radio
  different care easy security building.
