<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2024-951
Date of Submission: 2024-09-19

This report was submitted by a Pharmacist from Ellis, White and Hernandez Medical Center concerning patient ANON-PX-3679. The subject is a 85-year-old other with a significant medical history including chronic kidney disease, type 2 diabetes. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Sertraline administered via the Intravenous route at a dosage of 431mg, initiated on 2024-08-19 for Major depressive disorder and discontinued on 2024-09-16; Levothyroxine (Thyroid hormone) administered via the Intramuscular route at a dosage of 278mg, initiated on 2024-08-19 for Hypothyroidism and discontinued on 2024-09-16.

On approximately 2024-08-28, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Angioedema, Headache. The Angioedema was classified as Severe in severity. This necessitated clinical intervention. The documented action was: Prescribed myself and advised wind. The current patient status regarding this symptom is 'Not Recovered'. The Headache was classified as Moderate in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovered'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. A Naranjo score of 7 was calculated, The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Rechallenge not performed'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: You where get few each herself imagine. News country agency mouth watch. Candidate system think radio life drug floor.</data>
report_id: ADR-2024-951
report_date: '2024-09-19'
patient_details:
  patient_id: ANON-PX-3679
  gender: Other
  relevant_history:
  - chronic kidney disease
  - type 2 diabetes
  age_at_reaction: 85
suspected_drugs:
- drug_name: Sertraline
  dosage: 431mg
  route_of_administration: Intravenous
  start_date: '2024-08-19'
  indication_for_use: Major depressive disorder
  end_date: '2024-09-16'
- drug_name: Levothyroxine
  dosage: 278mg
  route_of_administration: Intramuscular
  start_date: '2024-08-19'
  indication_for_use: Hypothyroidism
  drug_class: Thyroid hormone
  end_date: '2024-09-16'
adverse_reactions:
- symptom_name: Angioedema
  onset_date: '2024-08-28'
  severity: Severe
  outcome: Not Recovered
  intervention_required: true
  intervention_details: Prescribed myself and advised wind.
- symptom_name: Headache
  onset_date: '2024-08-28'
  severity: Moderate
  outcome: Recovered
  intervention_required: false
causality_assessment:
  assessment_conclusion: Probable
  dechallenge_rechallenge: Rechallenge not performed
  naranjo_score: 7
reporting_facility: Ellis, White and Hernandez Medical Center
reporter_type: Pharmacist
notes: You where get few each herself imagine. News country agency mouth watch. Candidate
  system think radio life drug floor.
