<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2024-674
Date of Submission: 2024-12-22

This report was submitted by a Other Healthcare Professional from Larson, Smith and Mcpherson Medical Center concerning patient ANON-PX-8485. The subject is a 61-year-old male with a significant medical history including type 2 diabetes, coronary artery disease. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Warfarin (Anticoagulant) administered via the Intravenous route at a dosage of 332mg, initiated on 2024-12-11 for Thromboembolism prevention with the course ongoing.

On approximately 2024-12-17, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Nausea, Maculopapular Rash, Vomiting, Angioedema. The Nausea was classified as Severe in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Not Recovered'. The Maculopapular Rash was classified as Severe in severity. This necessitated clinical intervention. The documented action was: Prescribed here and advised all. The current patient status regarding this symptom is 'Recovered'. The Vomiting was classified as Moderate in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovered'. The Angioedema was classified as Moderate in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Unknown'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. A Naranjo score of 4 was calculated, The assessment concluded the relationship was 'Possible'. Dechallenge/Rechallenge status was noted as: 'Positive dechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Speak far father music nature. Next clear size story fall line hit call. Easy than along walk keep life black.</data>
report_id: ADR-2024-674
report_date: '2024-12-22'
patient_details:
  patient_id: ANON-PX-8485
  gender: Male
  relevant_history:
  - type 2 diabetes
  - coronary artery disease
  age_at_reaction: 61
suspected_drugs:
- drug_name: Warfarin
  dosage: 332mg
  route_of_administration: Intravenous
  start_date: '2024-12-11'
  indication_for_use: Thromboembolism prevention
  drug_class: Anticoagulant
adverse_reactions:
- symptom_name: Nausea
  onset_date: '2024-12-17'
  severity: Severe
  outcome: Not Recovered
  intervention_required: false
- symptom_name: Maculopapular Rash
  onset_date: '2024-12-17'
  severity: Severe
  outcome: Recovered
  intervention_required: true
  intervention_details: Prescribed here and advised all.
- symptom_name: Vomiting
  onset_date: '2024-12-17'
  severity: Moderate
  outcome: Recovered
  intervention_required: false
- symptom_name: Angioedema
  onset_date: '2024-12-17'
  severity: Moderate
  outcome: Unknown
  intervention_required: false
causality_assessment:
  assessment_conclusion: Possible
  dechallenge_rechallenge: Positive dechallenge
  naranjo_score: 4
reporting_facility: Larson, Smith and Mcpherson Medical Center
reporter_type: Other Healthcare Professional
notes: Speak far father music nature. Next clear size story fall line hit call. Easy
  than along walk keep life black.
