<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2025-717
Date of Submission: 2025-05-08

This report was submitted by a Nurse from Lamb, Garcia and Bartlett Medical Center concerning patient ANON-PX-6682. The subject is a 21-year-old male with a significant medical history including anxiety, asthma, migraines, atrial fibrillation. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Warfarin (Anticoagulant) administered via the Topical route at a dosage of 433mg, initiated on 2025-02-15 for Thromboembolism prevention and discontinued on 2025-04-29.

On approximately 2025-04-01, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Pruritus, Maculopapular Rash. The Pruritus was classified as Severe in severity. This necessitated clinical intervention. The documented action was: Prescribed each and advised program. The current patient status regarding this symptom is 'Unknown'. The Maculopapular Rash was classified as Life-threatening in severity. This necessitated clinical intervention. The documented action was: Prescribed decision and advised capital. The current patient status regarding this symptom is 'Recovered'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Negative dechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Air language staff major. Discuss modern player method that.</data>
report_id: ADR-2025-717
report_date: '2025-05-08'
patient_details:
  patient_id: ANON-PX-6682
  gender: Male
  relevant_history:
  - anxiety
  - asthma
  - migraines
  - atrial fibrillation
  age_at_reaction: 21
suspected_drugs:
- drug_name: Warfarin
  dosage: 433mg
  route_of_administration: Topical
  start_date: '2025-02-15'
  indication_for_use: Thromboembolism prevention
  drug_class: Anticoagulant
  end_date: '2025-04-29'
adverse_reactions:
- symptom_name: Pruritus
  onset_date: '2025-04-01'
  severity: Severe
  outcome: Unknown
  intervention_required: true
  intervention_details: Prescribed each and advised program.
- symptom_name: Maculopapular Rash
  onset_date: '2025-04-01'
  severity: Life-threatening
  outcome: Recovered
  intervention_required: true
  intervention_details: Prescribed decision and advised capital.
causality_assessment:
  assessment_conclusion: Probable
  dechallenge_rechallenge: Negative dechallenge
reporting_facility: Lamb, Garcia and Bartlett Medical Center
reporter_type: Nurse
notes: Air language staff major. Discuss modern player method that.
