<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2025-934
Date of Submission: 2025-08-09

This report was submitted by a Other Healthcare Professional from Garcia, Sims and Dominguez Medical Center concerning patient ANON-PX-4004. The subject is a 24-year-old other with a significant medical history including hypertension, anxiety. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Ibuprofen (NSAID) administered via the Topical route at a dosage of 278mg, initiated on 2025-07-20 for Pain and inflammation and discontinued on 2025-08-07.

On approximately 2025-08-07, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Dizziness, Vomiting, Somnolence, Headache, Stevens-Johnson syndrome. The Dizziness was classified as Severe in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Fatal'. The Vomiting was classified as Moderate in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Unknown'. The Somnolence was classified as Severe in severity. This necessitated clinical intervention. The current patient status regarding this symptom is 'Fatal'. The Headache was classified as Life-threatening in severity. This necessitated clinical intervention. The documented action was: Prescribed top and advised report. The current patient status regarding this symptom is 'Recovering'. The Stevens-Johnson syndrome was classified as Moderate in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Unknown'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. A Naranjo score of 10 was calculated, The assessment concluded the relationship was 'Highly Probable'. Dechallenge/Rechallenge status was noted as: 'Not applicable'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Future weight force business find. Remember wall interesting away enjoy station fact.</data>
report_id: ADR-2025-934
report_date: '2025-08-09'
patient_details:
  patient_id: ANON-PX-4004
  gender: Other
  relevant_history:
  - hypertension
  - anxiety
  age_at_reaction: 24
suspected_drugs:
- drug_name: Ibuprofen
  dosage: 278mg
  route_of_administration: Topical
  start_date: '2025-07-20'
  indication_for_use: Pain and inflammation
  drug_class: NSAID
  end_date: '2025-08-07'
adverse_reactions:
- symptom_name: Dizziness
  onset_date: '2025-08-07'
  severity: Severe
  outcome: Fatal
  intervention_required: false
- symptom_name: Vomiting
  onset_date: '2025-08-07'
  severity: Moderate
  outcome: Unknown
  intervention_required: false
- symptom_name: Somnolence
  onset_date: '2025-08-07'
  severity: Severe
  outcome: Fatal
  intervention_required: true
- symptom_name: Headache
  onset_date: '2025-08-07'
  severity: Life-threatening
  outcome: Recovering
  intervention_required: true
  intervention_details: Prescribed top and advised report.
- symptom_name: Stevens-Johnson syndrome
  onset_date: '2025-08-07'
  severity: Moderate
  outcome: Unknown
  intervention_required: false
causality_assessment:
  assessment_conclusion: Highly Probable
  dechallenge_rechallenge: Not applicable
  naranjo_score: 10
reporting_facility: Garcia, Sims and Dominguez Medical Center
reporter_type: Other Healthcare Professional
notes: Future weight force business find. Remember wall interesting away enjoy station
  fact.
