<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2025-791
Date of Submission: 2025-05-03

This report was submitted by a Pharmacist from Hamilton, Harrison and Bates Medical Center concerning patient ANON-PX-7185. The subject is an adult other with a significant medical history including seasonal allergies, hypertension, migraines. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Warfarin (Anticoagulant) administered via the Topical route at a dosage of 454mg, initiated on 2025-04-03 for Thromboembolism prevention and discontinued on 2025-05-01; Atorvastatin (Statin) administered via the Subcutaneous route at a dosage of 391mg, initiated on 2025-04-03 for Hypercholesterolemia and discontinued on 2025-05-01.

On approximately 2025-04-20, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Angioedema, Nausea, Pruritus, Dizziness, Diarrhea. The Angioedema was classified as Severe in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovered'. The Nausea was classified as Moderate in severity. This necessitated clinical intervention. The current patient status regarding this symptom is 'Unknown'. The Pruritus was classified as Mild in severity. This necessitated clinical intervention. The documented action was: Prescribed local and advised word. The current patient status regarding this symptom is 'Unknown'. The Dizziness was classified as Mild in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Not Recovered'. The Diarrhea was classified as Moderate in severity. This necessitated clinical intervention. The documented action was: Prescribed must and advised area. The current patient status regarding this symptom is 'Fatal'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. A Naranjo score of 3 was calculated, The assessment concluded the relationship was 'Possible'. Dechallenge/Rechallenge status was noted as: 'Rechallenge not performed'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Any policy person mean. Many sea let them out short between station. Already whether foot in draw. Race identify knowledge media debate.</data>
report_id: ADR-2025-791
report_date: '2025-05-03'
patient_details:
  patient_id: ANON-PX-7185
  gender: Other
  relevant_history:
  - seasonal allergies
  - hypertension
  - migraines
suspected_drugs:
- drug_name: Warfarin
  dosage: 454mg
  route_of_administration: Topical
  start_date: '2025-04-03'
  indication_for_use: Thromboembolism prevention
  drug_class: Anticoagulant
  end_date: '2025-05-01'
- drug_name: Atorvastatin
  dosage: 391mg
  route_of_administration: Subcutaneous
  start_date: '2025-04-03'
  indication_for_use: Hypercholesterolemia
  drug_class: Statin
  end_date: '2025-05-01'
adverse_reactions:
- symptom_name: Angioedema
  onset_date: '2025-04-20'
  severity: Severe
  outcome: Recovered
  intervention_required: false
- symptom_name: Nausea
  onset_date: '2025-04-20'
  severity: Moderate
  outcome: Unknown
  intervention_required: true
- symptom_name: Pruritus
  onset_date: '2025-04-20'
  severity: Mild
  outcome: Unknown
  intervention_required: true
  intervention_details: Prescribed local and advised word.
- symptom_name: Dizziness
  onset_date: '2025-04-20'
  severity: Mild
  outcome: Not Recovered
  intervention_required: false
- symptom_name: Diarrhea
  onset_date: '2025-04-20'
  severity: Moderate
  outcome: Fatal
  intervention_required: true
  intervention_details: Prescribed must and advised area.
causality_assessment:
  assessment_conclusion: Possible
  dechallenge_rechallenge: Rechallenge not performed
  naranjo_score: 3
reporting_facility: Hamilton, Harrison and Bates Medical Center
reporter_type: Pharmacist
notes: Any policy person mean. Many sea let them out short between station. Already
  whether foot in draw. Race identify knowledge media debate.
