<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2025-811
Date of Submission: 2025-02-11

This report was submitted by a Pharmacist from Keller Group Medical Center concerning patient ANON-PX-2640. The subject is a 53-year-old other with a significant medical history including migraines, osteoarthritis, coronary artery disease. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Levothyroxine (Thyroid hormone) administered via the Intravenous route at a dosage of 23mg, initiated on 2024-12-02 for Hypothyroidism and discontinued on 2025-02-09; Sertraline administered via the Intravenous route at a dosage of 363mg, initiated on 2024-12-02 for Major depressive disorder and discontinued on 2025-02-09.

On approximately 2025-02-07, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Headache, Nausea, Anaphylaxis, Maculopapular Rash. The Headache was classified as Life-threatening in severity. This necessitated clinical intervention. The current patient status regarding this symptom is 'Recovered'. The Nausea was classified as Life-threatening in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovered'. The Anaphylaxis was classified as Moderate in severity. This necessitated clinical intervention. The documented action was: Prescribed however and advised success. The current patient status regarding this symptom is 'Fatal'. The Maculopapular Rash was classified as Moderate in severity. This necessitated clinical intervention. The documented action was: Prescribed could and advised some. The current patient status regarding this symptom is 'Fatal'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. A Naranjo score of 9 was calculated, The assessment concluded the relationship was 'Highly Probable'. Dechallenge/Rechallenge status was noted as: 'Not applicable'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Treat those behavior society just. Perform finish check speech degree medical. Us throughout catch firm serious budget main task.</data>
report_id: ADR-2025-811
report_date: '2025-02-11'
patient_details:
  patient_id: ANON-PX-2640
  gender: Other
  relevant_history:
  - migraines
  - osteoarthritis
  - coronary artery disease
  age_at_reaction: 53
suspected_drugs:
- drug_name: Levothyroxine
  dosage: 23mg
  route_of_administration: Intravenous
  start_date: '2024-12-02'
  indication_for_use: Hypothyroidism
  drug_class: Thyroid hormone
  end_date: '2025-02-09'
- drug_name: Sertraline
  dosage: 363mg
  route_of_administration: Intravenous
  start_date: '2024-12-02'
  indication_for_use: Major depressive disorder
  end_date: '2025-02-09'
adverse_reactions:
- symptom_name: Headache
  onset_date: '2025-02-07'
  severity: Life-threatening
  outcome: Recovered
  intervention_required: true
- symptom_name: Nausea
  onset_date: '2025-02-07'
  severity: Life-threatening
  outcome: Recovered
  intervention_required: false
- symptom_name: Anaphylaxis
  onset_date: '2025-02-07'
  severity: Moderate
  outcome: Fatal
  intervention_required: true
  intervention_details: Prescribed however and advised success.
- symptom_name: Maculopapular Rash
  onset_date: '2025-02-07'
  severity: Moderate
  outcome: Fatal
  intervention_required: true
  intervention_details: Prescribed could and advised some.
causality_assessment:
  assessment_conclusion: Highly Probable
  dechallenge_rechallenge: Not applicable
  naranjo_score: 9
reporting_facility: Keller Group Medical Center
reporter_type: Pharmacist
notes: Treat those behavior society just. Perform finish check speech degree medical.
  Us throughout catch firm serious budget main task.
