<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2025-774
Date of Submission: 2025-07-31

This report was submitted by a Nurse from Vang, Taylor and Romero Medical Center concerning patient ANON-PX-3875. The subject is an adult male with a significant medical history including coronary artery disease, hypertension, seasonal allergies. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Omeprazole (Proton-pump inhibitor) administered via the Intravenous route at a dosage of 222mg, initiated on 2025-07-12 for Gastroesophageal reflux disease with the course ongoing; Sertraline (SSRI) administered via the Oral route at a dosage of 181mg, initiated on 2025-07-12 for Major depressive disorder with the course ongoing.

On approximately 2025-07-27, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Angioedema, Headache. The Angioedema was classified as Mild in severity. This necessitated clinical intervention. The current patient status regarding this symptom is 'Recovered'. The Headache was classified as Mild in severity. This necessitated clinical intervention. The documented action was: Prescribed more and advised hope. The current patient status regarding this symptom is 'Not Recovered'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. A Naranjo score of 10 was calculated, The assessment concluded the relationship was 'Highly Probable'. Dechallenge/Rechallenge status was noted as: 'Not applicable'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Sit apply group should meeting right red.</data>
report_id: ADR-2025-774
report_date: '2025-07-31'
patient_details:
  patient_id: ANON-PX-3875
  gender: Male
  relevant_history:
  - coronary artery disease
  - hypertension
  - seasonal allergies
suspected_drugs:
- drug_name: Omeprazole
  dosage: 222mg
  route_of_administration: Intravenous
  start_date: '2025-07-12'
  indication_for_use: Gastroesophageal reflux disease
  drug_class: Proton-pump inhibitor
- drug_name: Sertraline
  dosage: 181mg
  route_of_administration: Oral
  start_date: '2025-07-12'
  indication_for_use: Major depressive disorder
  drug_class: SSRI
adverse_reactions:
- symptom_name: Angioedema
  onset_date: '2025-07-27'
  severity: Mild
  outcome: Recovered
  intervention_required: true
- symptom_name: Headache
  onset_date: '2025-07-27'
  severity: Mild
  outcome: Not Recovered
  intervention_required: true
  intervention_details: Prescribed more and advised hope.
causality_assessment:
  assessment_conclusion: Highly Probable
  dechallenge_rechallenge: Not applicable
  naranjo_score: 10
reporting_facility: Vang, Taylor and Romero Medical Center
reporter_type: Nurse
notes: Sit apply group should meeting right red.
