<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2025-322
Date of Submission: 2025-04-10

This report was submitted by a Physician from Kim PLC Medical Center concerning patient ANON-PX-2611. The subject is a 52-year-old female with a significant medical history including chronic kidney disease, seasonal allergies, migraines. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Gabapentin (Anticonvulsant) administered via the Subcutaneous route at a dosage of 467mg, initiated on 2025-04-01 for Neuropathic pain and discontinued on 2025-04-09.

On approximately 2025-04-05, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Diarrhea, Stevens-Johnson syndrome, Hepatotoxicity, Headache. The Diarrhea was classified as Moderate in severity. This necessitated clinical intervention. The current patient status regarding this symptom is 'Recovering'. The Stevens-Johnson syndrome was classified as Life-threatening in severity. This necessitated clinical intervention. The documented action was: Prescribed school and advised owner. The current patient status regarding this symptom is 'Fatal'. The Hepatotoxicity was classified as Moderate in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Unknown'. The Headache was classified as Moderate in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Unknown'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. A Naranjo score of 2 was calculated, The assessment concluded the relationship was 'Possible'. Dechallenge/Rechallenge status was noted as: 'Positive rechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Deal fly necessary into capital. Gun artist material professional until. Issue thank street also.</data>
report_id: ADR-2025-322
report_date: '2025-04-10'
patient_details:
  patient_id: ANON-PX-2611
  gender: Female
  relevant_history:
  - chronic kidney disease
  - seasonal allergies
  - migraines
  age_at_reaction: 52
suspected_drugs:
- drug_name: Gabapentin
  dosage: 467mg
  route_of_administration: Subcutaneous
  start_date: '2025-04-01'
  indication_for_use: Neuropathic pain
  drug_class: Anticonvulsant
  end_date: '2025-04-09'
adverse_reactions:
- symptom_name: Diarrhea
  onset_date: '2025-04-05'
  severity: Moderate
  outcome: Recovering
  intervention_required: true
- symptom_name: Stevens-Johnson syndrome
  onset_date: '2025-04-05'
  severity: Life-threatening
  outcome: Fatal
  intervention_required: true
  intervention_details: Prescribed school and advised owner.
- symptom_name: Hepatotoxicity
  onset_date: '2025-04-05'
  severity: Moderate
  outcome: Unknown
  intervention_required: false
- symptom_name: Headache
  onset_date: '2025-04-05'
  severity: Moderate
  outcome: Unknown
  intervention_required: false
causality_assessment:
  assessment_conclusion: Possible
  dechallenge_rechallenge: Positive rechallenge
  naranjo_score: 2
reporting_facility: Kim PLC Medical Center
reporter_type: Physician
notes: Deal fly necessary into capital. Gun artist material professional until. Issue
  thank street also.
