<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2024-802
Date of Submission: 2024-11-23

This report was submitted by a Pharmacist from Williams-Chapman Medical Center concerning patient ANON-PX-6125. The subject is a 66-year-old male with a significant medical history including seasonal allergies, migraines. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Lisinopril administered via the Oral route at a dosage of 445mg, initiated on 2024-10-20 for Hypertension and discontinued on 2024-11-17.

On approximately 2024-11-13, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Anaphylaxis, Pruritus, Hepatotoxicity. The Anaphylaxis was classified as Mild in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Not Recovered'. The Pruritus was classified as Mild in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Fatal'. The Hepatotoxicity was classified as Mild in severity. This necessitated clinical intervention. The documented action was: Prescribed window and advised everything. The current patient status regarding this symptom is 'Recovered'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Rechallenge not performed'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Marriage lot seven. Medical listen four again set provide back. Hand most international summer member that wall.</data>
report_id: ADR-2024-802
report_date: '2024-11-23'
patient_details:
  patient_id: ANON-PX-6125
  gender: Male
  relevant_history:
  - seasonal allergies
  - migraines
  age_at_reaction: 66
suspected_drugs:
- drug_name: Lisinopril
  dosage: 445mg
  route_of_administration: Oral
  start_date: '2024-10-20'
  indication_for_use: Hypertension
  end_date: '2024-11-17'
adverse_reactions:
- symptom_name: Anaphylaxis
  onset_date: '2024-11-13'
  severity: Mild
  outcome: Not Recovered
  intervention_required: false
- symptom_name: Pruritus
  onset_date: '2024-11-13'
  severity: Mild
  outcome: Fatal
  intervention_required: false
- symptom_name: Hepatotoxicity
  onset_date: '2024-11-13'
  severity: Mild
  outcome: Recovered
  intervention_required: true
  intervention_details: Prescribed window and advised everything.
causality_assessment:
  assessment_conclusion: Probable
  dechallenge_rechallenge: Rechallenge not performed
reporting_facility: Williams-Chapman Medical Center
reporter_type: Pharmacist
notes: Marriage lot seven. Medical listen four again set provide back. Hand most international
  summer member that wall.
