<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2024-230
Date of Submission: 2024-10-12

This report was submitted by a Other Healthcare Professional from Hampton Inc Medical Center concerning patient ANON-PX-2219. The subject is a 77-year-old other with a significant medical history including anxiety, chronic kidney disease, asthma. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Metformin administered via the Subcutaneous route at a dosage of 434mg, initiated on 2024-07-14 for Type 2 diabetes with the course ongoing.

On approximately 2024-07-21, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Stevens-Johnson syndrome, Nausea, Angioedema, Somnolence, Dizziness. The Stevens-Johnson syndrome was classified as Moderate in severity. This necessitated clinical intervention. The documented action was: Prescribed knowledge and advised anything. The current patient status regarding this symptom is 'Not Recovered'. The Nausea was classified as Mild in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Fatal'. The Angioedema was classified as Severe in severity. This necessitated clinical intervention. The current patient status regarding this symptom is 'Recovered'. The Somnolence was classified as Moderate in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovered'. The Dizziness was classified as Life-threatening in severity. This necessitated clinical intervention. The documented action was: Prescribed country and advised too. The current patient status regarding this symptom is 'Recovered'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Rechallenge not performed'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Travel ago team agent pressure beyond.</data>
report_id: ADR-2024-230
report_date: '2024-10-12'
patient_details:
  patient_id: ANON-PX-2219
  gender: Other
  relevant_history:
  - anxiety
  - chronic kidney disease
  - asthma
  age_at_reaction: 77
suspected_drugs:
- drug_name: Metformin
  dosage: 434mg
  route_of_administration: Subcutaneous
  start_date: '2024-07-14'
  indication_for_use: Type 2 diabetes
adverse_reactions:
- symptom_name: Stevens-Johnson syndrome
  onset_date: '2024-07-21'
  severity: Moderate
  outcome: Not Recovered
  intervention_required: true
  intervention_details: Prescribed knowledge and advised anything.
- symptom_name: Nausea
  onset_date: '2024-07-21'
  severity: Mild
  outcome: Fatal
  intervention_required: false
- symptom_name: Angioedema
  onset_date: '2024-07-21'
  severity: Severe
  outcome: Recovered
  intervention_required: true
- symptom_name: Somnolence
  onset_date: '2024-07-21'
  severity: Moderate
  outcome: Recovered
  intervention_required: false
- symptom_name: Dizziness
  onset_date: '2024-07-21'
  severity: Life-threatening
  outcome: Recovered
  intervention_required: true
  intervention_details: Prescribed country and advised too.
causality_assessment:
  assessment_conclusion: Probable
  dechallenge_rechallenge: Rechallenge not performed
reporting_facility: Hampton Inc Medical Center
reporter_type: Other Healthcare Professional
notes: Travel ago team agent pressure beyond.
