<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2025-697
Date of Submission: 2025-03-19

This report was submitted by a Other Healthcare Professional from Carroll, Garner and Miller Medical Center concerning patient ANON-PX-1923. The subject is a 22-year-old other with a significant medical history including osteoarthritis, asthma. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Sertraline (SSRI) administered via the Intravenous route at a dosage of 86mg, initiated on 2025-01-22 for Major depressive disorder with the course ongoing; Warfarin (Anticoagulant) administered via the Topical route at a dosage of 306mg, initiated on 2025-01-22 for Thromboembolism prevention with the course ongoing.

On approximately 2025-02-02, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Stevens-Johnson syndrome, Diarrhea, Nausea. The Stevens-Johnson syndrome was classified as Mild in severity. This necessitated clinical intervention. The documented action was: Prescribed check and advised professional. The current patient status regarding this symptom is 'Recovering'. The Diarrhea was classified as Life-threatening in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Unknown'. The Nausea was classified as Life-threatening in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Not Recovered'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. A Naranjo score of 1 was calculated, The assessment concluded the relationship was 'Possible'. Dechallenge/Rechallenge status was noted as: 'Negative dechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. 

</data>
report_id: ADR-2025-697
report_date: '2025-03-19'
patient_details:
  patient_id: ANON-PX-1923
  gender: Other
  relevant_history:
  - osteoarthritis
  - asthma
  age_at_reaction: 22
suspected_drugs:
- drug_name: Sertraline
  dosage: 86mg
  route_of_administration: Intravenous
  start_date: '2025-01-22'
  indication_for_use: Major depressive disorder
  drug_class: SSRI
- drug_name: Warfarin
  dosage: 306mg
  route_of_administration: Topical
  start_date: '2025-01-22'
  indication_for_use: Thromboembolism prevention
  drug_class: Anticoagulant
adverse_reactions:
- symptom_name: Stevens-Johnson syndrome
  onset_date: '2025-02-02'
  severity: Mild
  outcome: Recovering
  intervention_required: true
  intervention_details: Prescribed check and advised professional.
- symptom_name: Diarrhea
  onset_date: '2025-02-02'
  severity: Life-threatening
  outcome: Unknown
  intervention_required: false
- symptom_name: Nausea
  onset_date: '2025-02-02'
  severity: Life-threatening
  outcome: Not Recovered
  intervention_required: false
causality_assessment:
  assessment_conclusion: Possible
  dechallenge_rechallenge: Negative dechallenge
  naranjo_score: 1
reporting_facility: Carroll, Garner and Miller Medical Center
reporter_type: Other Healthcare Professional
