<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2025-781
Date of Submission: 2025-02-09

This report was submitted by a Other Healthcare Professional from Shaw-Ross Medical Center concerning patient ANON-PX-7483. The subject is a 87-year-old male with a significant medical history including atrial fibrillation, coronary artery disease, anxiety. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Levothyroxine (Thyroid hormone) administered via the Intravenous route at a dosage of 196mg, initiated on 2024-11-20 for Hypothyroidism with the course ongoing.

On approximately 2025-01-24, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Pruritus, Nausea. The Pruritus was classified as Life-threatening in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovered'. The Nausea was classified as Severe in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Fatal'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Positive dechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Need parent indeed common seven. Strategy watch participant body treatment may nothing.</data>
report_id: ADR-2025-781
report_date: '2025-02-09'
patient_details:
  patient_id: ANON-PX-7483
  gender: Male
  relevant_history:
  - atrial fibrillation
  - coronary artery disease
  - anxiety
  age_at_reaction: 87
suspected_drugs:
- drug_name: Levothyroxine
  dosage: 196mg
  route_of_administration: Intravenous
  start_date: '2024-11-20'
  indication_for_use: Hypothyroidism
  drug_class: Thyroid hormone
adverse_reactions:
- symptom_name: Pruritus
  onset_date: '2025-01-24'
  severity: Life-threatening
  outcome: Recovered
  intervention_required: false
- symptom_name: Nausea
  onset_date: '2025-01-24'
  severity: Severe
  outcome: Fatal
  intervention_required: false
causality_assessment:
  assessment_conclusion: Probable
  dechallenge_rechallenge: Positive dechallenge
reporting_facility: Shaw-Ross Medical Center
reporter_type: Other Healthcare Professional
notes: Need parent indeed common seven. Strategy watch participant body treatment
  may nothing.
