<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2024-120
Date of Submission: 2024-09-26

This report was submitted by a Other Healthcare Professional from Harmon-Galvan Medical Center concerning patient ANON-PX-2662. The subject is an adult female with a significant medical history including chronic kidney disease, anxiety, asthma. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Atorvastatin (Statin) administered via the Intramuscular route at a dosage of 111mg, initiated on 2024-07-07 for Hypercholesterolemia with the course ongoing; Warfarin (Anticoagulant) administered via the Topical route at a dosage of 462mg, initiated on 2024-07-07 for Thromboembolism prevention with the course ongoing.

On approximately 2024-09-21, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Pruritus, Anaphylaxis, Dizziness, Nausea, Headache. The Pruritus was classified as Severe in severity. This necessitated clinical intervention. The documented action was: Prescribed look and advised expert. The current patient status regarding this symptom is 'Unknown'. The Anaphylaxis was classified as Severe in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovered'. The Dizziness was classified as Moderate in severity. This necessitated clinical intervention. The documented action was: Prescribed over and advised right. The current patient status regarding this symptom is 'Not Recovered'. The Nausea was classified as Moderate in severity. This necessitated clinical intervention. The current patient status regarding this symptom is 'Recovered'. The Headache was classified as Life-threatening in severity. This necessitated clinical intervention. The documented action was: Prescribed administration and advised onto. The current patient status regarding this symptom is 'Recovered'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Not applicable'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Finally own must beyond. Range worker manager.</data>
report_id: ADR-2024-120
report_date: '2024-09-26'
patient_details:
  patient_id: ANON-PX-2662
  gender: Female
  relevant_history:
  - chronic kidney disease
  - anxiety
  - asthma
suspected_drugs:
- drug_name: Atorvastatin
  dosage: 111mg
  route_of_administration: Intramuscular
  start_date: '2024-07-07'
  indication_for_use: Hypercholesterolemia
  drug_class: Statin
- drug_name: Warfarin
  dosage: 462mg
  route_of_administration: Topical
  start_date: '2024-07-07'
  indication_for_use: Thromboembolism prevention
  drug_class: Anticoagulant
adverse_reactions:
- symptom_name: Pruritus
  onset_date: '2024-09-21'
  severity: Severe
  outcome: Unknown
  intervention_required: true
  intervention_details: Prescribed look and advised expert.
- symptom_name: Anaphylaxis
  onset_date: '2024-09-21'
  severity: Severe
  outcome: Recovered
  intervention_required: false
- symptom_name: Dizziness
  onset_date: '2024-09-21'
  severity: Moderate
  outcome: Not Recovered
  intervention_required: true
  intervention_details: Prescribed over and advised right.
- symptom_name: Nausea
  onset_date: '2024-09-21'
  severity: Moderate
  outcome: Recovered
  intervention_required: true
- symptom_name: Headache
  onset_date: '2024-09-21'
  severity: Life-threatening
  outcome: Recovered
  intervention_required: true
  intervention_details: Prescribed administration and advised onto.
causality_assessment:
  assessment_conclusion: Probable
  dechallenge_rechallenge: Not applicable
reporting_facility: Harmon-Galvan Medical Center
reporter_type: Other Healthcare Professional
notes: Finally own must beyond. Range worker manager.
