<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2025-622
Date of Submission: 2025-05-01

This report was submitted by a Nurse from Walker, Shepard and Williams Medical Center concerning patient ANON-PX-8247. The subject is a 68-year-old male with a significant medical history including type 2 diabetes, seasonal allergies. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Sertraline (SSRI) administered via the Intravenous route at a dosage of 53mg, initiated on 2025-03-14 for Major depressive disorder and discontinued on 2025-04-09.

On approximately 2025-03-19, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Diarrhea, Angioedema, Anaphylaxis, Headache. The Diarrhea was classified as Severe in severity. This necessitated clinical intervention. The documented action was: Prescribed certain and advised big. The current patient status regarding this symptom is 'Unknown'. The Angioedema was classified as Mild in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Fatal'. The Anaphylaxis was classified as Life-threatening in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovering'. The Headache was classified as Moderate in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Fatal'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Negative dechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Later box newspaper foreign investment bar. Shake make white thank almost approach how. Light situation toward. Around fill care whether town guy day.</data>
report_id: ADR-2025-622
report_date: '2025-05-01'
patient_details:
  patient_id: ANON-PX-8247
  gender: Male
  relevant_history:
  - type 2 diabetes
  - seasonal allergies
  age_at_reaction: 68
suspected_drugs:
- drug_name: Sertraline
  dosage: 53mg
  route_of_administration: Intravenous
  start_date: '2025-03-14'
  indication_for_use: Major depressive disorder
  drug_class: SSRI
  end_date: '2025-04-09'
adverse_reactions:
- symptom_name: Diarrhea
  onset_date: '2025-03-19'
  severity: Severe
  outcome: Unknown
  intervention_required: true
  intervention_details: Prescribed certain and advised big.
- symptom_name: Angioedema
  onset_date: '2025-03-19'
  severity: Mild
  outcome: Fatal
  intervention_required: false
- symptom_name: Anaphylaxis
  onset_date: '2025-03-19'
  severity: Life-threatening
  outcome: Recovering
  intervention_required: false
- symptom_name: Headache
  onset_date: '2025-03-19'
  severity: Moderate
  outcome: Fatal
  intervention_required: false
causality_assessment:
  assessment_conclusion: Probable
  dechallenge_rechallenge: Negative dechallenge
reporting_facility: Walker, Shepard and Williams Medical Center
reporter_type: Nurse
notes: Later box newspaper foreign investment bar. Shake make white thank almost approach
  how. Light situation toward. Around fill care whether town guy day.
