<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2024-159
Date of Submission: 2024-10-30

This report was submitted by a Nurse from Wilson Ltd Medical Center concerning patient ANON-PX-4587. The subject is a 87-year-old male with a significant medical history including anxiety, atrial fibrillation, seasonal allergies, osteoarthritis. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Levothyroxine administered via the Intravenous route at a dosage of 235mg, initiated on 2024-10-14 for Hypothyroidism with the course ongoing.

On approximately 2024-10-23, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Anaphylaxis, Angioedema, Pruritus. The Anaphylaxis was classified as Life-threatening in severity. This necessitated clinical intervention. The current patient status regarding this symptom is 'Recovered'. The Angioedema was classified as Life-threatening in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovered'. The Pruritus was classified as Moderate in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Not Recovered'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Rechallenge not performed'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Job often say cell. Must gun look. Rise professional born action. Mother final mean want energy.</data>
report_id: ADR-2024-159
report_date: '2024-10-30'
patient_details:
  patient_id: ANON-PX-4587
  gender: Male
  relevant_history:
  - anxiety
  - atrial fibrillation
  - seasonal allergies
  - osteoarthritis
  age_at_reaction: 87
suspected_drugs:
- drug_name: Levothyroxine
  dosage: 235mg
  route_of_administration: Intravenous
  start_date: '2024-10-14'
  indication_for_use: Hypothyroidism
adverse_reactions:
- symptom_name: Anaphylaxis
  onset_date: '2024-10-23'
  severity: Life-threatening
  outcome: Recovered
  intervention_required: true
- symptom_name: Angioedema
  onset_date: '2024-10-23'
  severity: Life-threatening
  outcome: Recovered
  intervention_required: false
- symptom_name: Pruritus
  onset_date: '2024-10-23'
  severity: Moderate
  outcome: Not Recovered
  intervention_required: false
causality_assessment:
  assessment_conclusion: Probable
  dechallenge_rechallenge: Rechallenge not performed
reporting_facility: Wilson Ltd Medical Center
reporter_type: Nurse
notes: Job often say cell. Must gun look. Rise professional born action. Mother final
  mean want energy.
