<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2025-567
Date of Submission: 2025-07-29

This report was submitted by a Patient from Thomas-Reynolds Medical Center concerning patient ANON-PX-5110. The subject is a 57-year-old other with a significant medical history including hypertension, osteoarthritis, migraines. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Amoxicillin (Penicillin antibiotic) administered via the Oral route at a dosage of 401mg, initiated on 2025-07-19 for Bacterial infection with the course ongoing.

On approximately 2025-07-26, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Maculopapular Rash, Hepatotoxicity. The Maculopapular Rash was classified as Mild in severity. This necessitated clinical intervention. The documented action was: Prescribed wall and advised letter. The current patient status regarding this symptom is 'Recovering'. The Hepatotoxicity was classified as Life-threatening in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Unknown'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. A Naranjo score of 3 was calculated, The assessment concluded the relationship was 'Possible'. Dechallenge/Rechallenge status was noted as: 'Positive rechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Low record tend else economic move culture. Population early look truth. Money break senior relationship.</data>
report_id: ADR-2025-567
report_date: '2025-07-29'
patient_details:
  patient_id: ANON-PX-5110
  gender: Other
  relevant_history:
  - hypertension
  - osteoarthritis
  - migraines
  age_at_reaction: 57
suspected_drugs:
- drug_name: Amoxicillin
  dosage: 401mg
  route_of_administration: Oral
  start_date: '2025-07-19'
  indication_for_use: Bacterial infection
  drug_class: Penicillin antibiotic
adverse_reactions:
- symptom_name: Maculopapular Rash
  onset_date: '2025-07-26'
  severity: Mild
  outcome: Recovering
  intervention_required: true
  intervention_details: Prescribed wall and advised letter.
- symptom_name: Hepatotoxicity
  onset_date: '2025-07-26'
  severity: Life-threatening
  outcome: Unknown
  intervention_required: false
causality_assessment:
  assessment_conclusion: Possible
  dechallenge_rechallenge: Positive rechallenge
  naranjo_score: 3
reporting_facility: Thomas-Reynolds Medical Center
reporter_type: Patient
notes: Low record tend else economic move culture. Population early look truth. Money
  break senior relationship.
