<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2025-684
Date of Submission: 2025-01-11

This report was submitted by a Other Healthcare Professional from Hunter, White and Austin Medical Center concerning patient ANON-PX-5565. The subject is a 41-year-old other with a significant medical history including type 2 diabetes, anxiety, chronic kidney disease. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Omeprazole administered via the Intravenous route at a dosage of 209mg, initiated on 2024-11-19 for Gastroesophageal reflux disease and discontinued on 2025-01-05.

On approximately 2024-11-26, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Vomiting, Hepatotoxicity, Nausea, Somnolence. The Vomiting was classified as Mild in severity. This necessitated clinical intervention. The documented action was: Prescribed east and advised road. The current patient status regarding this symptom is 'Recovering'. The Hepatotoxicity was classified as Life-threatening in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Not Recovered'. The Nausea was classified as Moderate in severity. This necessitated clinical intervention. The documented action was: Prescribed argue and advised both. The current patient status regarding this symptom is 'Recovering'. The Somnolence was classified as Life-threatening in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovered'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. A Naranjo score of 5 was calculated, The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Positive dechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Time these eight financial face.</data>
report_id: ADR-2025-684
report_date: '2025-01-11'
patient_details:
  patient_id: ANON-PX-5565
  gender: Other
  relevant_history:
  - type 2 diabetes
  - anxiety
  - chronic kidney disease
  age_at_reaction: 41
suspected_drugs:
- drug_name: Omeprazole
  dosage: 209mg
  route_of_administration: Intravenous
  start_date: '2024-11-19'
  indication_for_use: Gastroesophageal reflux disease
  end_date: '2025-01-05'
adverse_reactions:
- symptom_name: Vomiting
  onset_date: '2024-11-26'
  severity: Mild
  outcome: Recovering
  intervention_required: true
  intervention_details: Prescribed east and advised road.
- symptom_name: Hepatotoxicity
  onset_date: '2024-11-26'
  severity: Life-threatening
  outcome: Not Recovered
  intervention_required: false
- symptom_name: Nausea
  onset_date: '2024-11-26'
  severity: Moderate
  outcome: Recovering
  intervention_required: true
  intervention_details: Prescribed argue and advised both.
- symptom_name: Somnolence
  onset_date: '2024-11-26'
  severity: Life-threatening
  outcome: Recovered
  intervention_required: false
causality_assessment:
  assessment_conclusion: Probable
  dechallenge_rechallenge: Positive dechallenge
  naranjo_score: 5
reporting_facility: Hunter, White and Austin Medical Center
reporter_type: Other Healthcare Professional
notes: Time these eight financial face.
