<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2025-882
Date of Submission: 2025-01-20

This report was submitted by a Physician from Patel, Garner and Arnold Medical Center concerning patient ANON-PX-2702. The subject is a 36-year-old other with a significant medical history including chronic kidney disease, seasonal allergies, type 2 diabetes. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Ibuprofen (NSAID) administered via the Subcutaneous route at a dosage of 223mg, initiated on 2024-12-21 for Pain and inflammation and discontinued on 2025-01-09.

On approximately 2024-12-27, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Stevens-Johnson syndrome, Angioedema. The Stevens-Johnson syndrome was classified as Moderate in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Fatal'. The Angioedema was classified as Moderate in severity. This necessitated clinical intervention. The current patient status regarding this symptom is 'Fatal'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. A Naranjo score of 1 was calculated, The assessment concluded the relationship was 'Possible'. Dechallenge/Rechallenge status was noted as: 'Positive rechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Keep whatever story professor strategy sort. Still go common off house form.</data>
report_id: ADR-2025-882
report_date: '2025-01-20'
patient_details:
  patient_id: ANON-PX-2702
  gender: Other
  relevant_history:
  - chronic kidney disease
  - seasonal allergies
  - type 2 diabetes
  age_at_reaction: 36
suspected_drugs:
- drug_name: Ibuprofen
  dosage: 223mg
  route_of_administration: Subcutaneous
  start_date: '2024-12-21'
  indication_for_use: Pain and inflammation
  drug_class: NSAID
  end_date: '2025-01-09'
adverse_reactions:
- symptom_name: Stevens-Johnson syndrome
  onset_date: '2024-12-27'
  severity: Moderate
  outcome: Fatal
  intervention_required: false
- symptom_name: Angioedema
  onset_date: '2024-12-27'
  severity: Moderate
  outcome: Fatal
  intervention_required: true
causality_assessment:
  assessment_conclusion: Possible
  dechallenge_rechallenge: Positive rechallenge
  naranjo_score: 1
reporting_facility: Patel, Garner and Arnold Medical Center
reporter_type: Physician
notes: Keep whatever story professor strategy sort. Still go common off house form.
