<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2024-587
Date of Submission: 2024-11-23

This report was submitted by a Physician from Barnes, Warner and Patterson Medical Center concerning patient ANON-PX-2205. The subject is a 41-year-old male with a significant medical history including type 2 diabetes, chronic kidney disease. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Sertraline administered via the Intravenous route at a dosage of 212mg, initiated on 2024-09-01 for Major depressive disorder and discontinued on 2024-11-09; Amoxicillin (Penicillin antibiotic) administered via the Oral route at a dosage of 104mg, initiated on 2024-09-01 for Bacterial infection and discontinued on 2024-11-09.

On approximately 2024-11-06, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Somnolence, Dizziness, Stevens-Johnson syndrome. The Somnolence was classified as Mild in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Not Recovered'. The Dizziness was classified as Moderate in severity. This necessitated clinical intervention. The current patient status regarding this symptom is 'Fatal'. The Stevens-Johnson syndrome was classified as Moderate in severity. This necessitated clinical intervention. The documented action was: Prescribed guess and advised plan. The current patient status regarding this symptom is 'Recovering'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Positive dechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Order society fire.</data>
report_id: ADR-2024-587
report_date: '2024-11-23'
patient_details:
  patient_id: ANON-PX-2205
  gender: Male
  relevant_history:
  - type 2 diabetes
  - chronic kidney disease
  age_at_reaction: 41
suspected_drugs:
- drug_name: Sertraline
  dosage: 212mg
  route_of_administration: Intravenous
  start_date: '2024-09-01'
  indication_for_use: Major depressive disorder
  end_date: '2024-11-09'
- drug_name: Amoxicillin
  dosage: 104mg
  route_of_administration: Oral
  start_date: '2024-09-01'
  indication_for_use: Bacterial infection
  drug_class: Penicillin antibiotic
  end_date: '2024-11-09'
adverse_reactions:
- symptom_name: Somnolence
  onset_date: '2024-11-06'
  severity: Mild
  outcome: Not Recovered
  intervention_required: false
- symptom_name: Dizziness
  onset_date: '2024-11-06'
  severity: Moderate
  outcome: Fatal
  intervention_required: true
- symptom_name: Stevens-Johnson syndrome
  onset_date: '2024-11-06'
  severity: Moderate
  outcome: Recovering
  intervention_required: true
  intervention_details: Prescribed guess and advised plan.
causality_assessment:
  assessment_conclusion: Probable
  dechallenge_rechallenge: Positive dechallenge
reporting_facility: Barnes, Warner and Patterson Medical Center
reporter_type: Physician
notes: Order society fire.
