<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2025-361
Date of Submission: 2025-02-18

This report was submitted by a Other Healthcare Professional from Bailey LLC Medical Center concerning patient ANON-PX-8095. The subject is a 85-year-old male with a significant medical history including osteoarthritis, anxiety, seasonal allergies. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Amoxicillin (Penicillin antibiotic) administered via the Oral route at a dosage of 277mg, initiated on 2024-12-25 for Bacterial infection and discontinued on 2025-01-25.

On approximately 2025-01-20, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Hepatotoxicity, Diarrhea. The Hepatotoxicity was classified as Life-threatening in severity. This necessitated clinical intervention. The documented action was: Prescribed strong and advised draw. The current patient status regarding this symptom is 'Recovered'. The Diarrhea was classified as Mild in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Fatal'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. A Naranjo score of 5 was calculated, The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Positive rechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Edge continue thank account ever other interview. Center management radio eye.</data>
report_id: ADR-2025-361
report_date: '2025-02-18'
patient_details:
  patient_id: ANON-PX-8095
  gender: Male
  relevant_history:
  - osteoarthritis
  - anxiety
  - seasonal allergies
  age_at_reaction: 85
suspected_drugs:
- drug_name: Amoxicillin
  dosage: 277mg
  route_of_administration: Oral
  start_date: '2024-12-25'
  indication_for_use: Bacterial infection
  drug_class: Penicillin antibiotic
  end_date: '2025-01-25'
adverse_reactions:
- symptom_name: Hepatotoxicity
  onset_date: '2025-01-20'
  severity: Life-threatening
  outcome: Recovered
  intervention_required: true
  intervention_details: Prescribed strong and advised draw.
- symptom_name: Diarrhea
  onset_date: '2025-01-20'
  severity: Mild
  outcome: Fatal
  intervention_required: false
causality_assessment:
  assessment_conclusion: Probable
  dechallenge_rechallenge: Positive rechallenge
  naranjo_score: 5
reporting_facility: Bailey LLC Medical Center
reporter_type: Other Healthcare Professional
notes: Edge continue thank account ever other interview. Center management radio eye.
