<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2025-740
Date of Submission: 2025-03-04

This report was submitted by a Nurse from Adams PLC Medical Center concerning patient ANON-PX-1217. The subject is a 90-year-old male with a significant medical history including seasonal allergies, chronic kidney disease. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Lisinopril (ACE inhibitor) administered via the Oral route at a dosage of 433mg, initiated on 2024-12-28 for Hypertension and discontinued on 2025-02-20.

On approximately 2025-01-18, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Pruritus, Dizziness, Headache, Anaphylaxis. The Pruritus was classified as Life-threatening in severity. This necessitated clinical intervention. The documented action was: Prescribed just and advised suddenly. The current patient status regarding this symptom is 'Recovered'. The Dizziness was classified as Life-threatening in severity. This necessitated clinical intervention. The documented action was: Prescribed just and advised far. The current patient status regarding this symptom is 'Recovered'. The Headache was classified as Life-threatening in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovered'. The Anaphylaxis was classified as Severe in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovered'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Negative dechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. 

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report_id: ADR-2025-740
report_date: '2025-03-04'
patient_details:
  patient_id: ANON-PX-1217
  gender: Male
  relevant_history:
  - seasonal allergies
  - chronic kidney disease
  age_at_reaction: 90
suspected_drugs:
- drug_name: Lisinopril
  dosage: 433mg
  route_of_administration: Oral
  start_date: '2024-12-28'
  indication_for_use: Hypertension
  drug_class: ACE inhibitor
  end_date: '2025-02-20'
adverse_reactions:
- symptom_name: Pruritus
  onset_date: '2025-01-18'
  severity: Life-threatening
  outcome: Recovered
  intervention_required: true
  intervention_details: Prescribed just and advised suddenly.
- symptom_name: Dizziness
  onset_date: '2025-01-18'
  severity: Life-threatening
  outcome: Recovered
  intervention_required: true
  intervention_details: Prescribed just and advised far.
- symptom_name: Headache
  onset_date: '2025-01-18'
  severity: Life-threatening
  outcome: Recovered
  intervention_required: false
- symptom_name: Anaphylaxis
  onset_date: '2025-01-18'
  severity: Severe
  outcome: Recovered
  intervention_required: false
causality_assessment:
  assessment_conclusion: Probable
  dechallenge_rechallenge: Negative dechallenge
reporting_facility: Adams PLC Medical Center
reporter_type: Nurse
notes: Energy commercial north memory challenge allow political. Why cell natural
  everything structure sound.
