<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2024-790
Date of Submission: 2024-09-24

This report was submitted by a Physician from Kim-Martin Medical Center concerning patient ANON-PX-3241. The subject is a 60-year-old male with a significant medical history including seasonal allergies, chronic kidney disease. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Levothyroxine (Thyroid hormone) administered via the Oral route at a dosage of 475mg, initiated on 2024-07-27 for Hypothyroidism with the course ongoing.

On approximately 2024-08-02, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Anaphylaxis, Angioedema. The Anaphylaxis was classified as Severe in severity. This necessitated clinical intervention. The documented action was: Prescribed first and advised month. The current patient status regarding this symptom is 'Not Recovered'. The Angioedema was classified as Severe in severity. This necessitated clinical intervention. The documented action was: Prescribed light and advised including. The current patient status regarding this symptom is 'Recovered'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Not applicable'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Effect seat character serious sit rather run blood. How movement vote dinner training. He forget natural rise. Unit before act dark of one.</data>
report_id: ADR-2024-790
report_date: '2024-09-24'
patient_details:
  patient_id: ANON-PX-3241
  gender: Male
  relevant_history:
  - seasonal allergies
  - chronic kidney disease
  age_at_reaction: 60
suspected_drugs:
- drug_name: Levothyroxine
  dosage: 475mg
  route_of_administration: Oral
  start_date: '2024-07-27'
  indication_for_use: Hypothyroidism
  drug_class: Thyroid hormone
adverse_reactions:
- symptom_name: Anaphylaxis
  onset_date: '2024-08-02'
  severity: Severe
  outcome: Not Recovered
  intervention_required: true
  intervention_details: Prescribed first and advised month.
- symptom_name: Angioedema
  onset_date: '2024-08-02'
  severity: Severe
  outcome: Recovered
  intervention_required: true
  intervention_details: Prescribed light and advised including.
causality_assessment:
  assessment_conclusion: Probable
  dechallenge_rechallenge: Not applicable
reporting_facility: Kim-Martin Medical Center
reporter_type: Physician
notes: Effect seat character serious sit rather run blood. How movement vote dinner
  training. He forget natural rise. Unit before act dark of one.
