<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2024-108
Date of Submission: 2024-09-20

This report was submitted by a Pharmacist from Lee-Rodriguez Medical Center concerning patient ANON-PX-5302. The subject is a 29-year-old female with a significant medical history including asthma, anxiety. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Warfarin administered via the Oral route at a dosage of 65mg, initiated on 2024-07-03 for Thromboembolism prevention with the course ongoing; Omeprazole (Proton-pump inhibitor) administered via the Intramuscular route at a dosage of 451mg, initiated on 2024-07-03 for Gastroesophageal reflux disease with the course ongoing.

On approximately 2024-09-10, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Dizziness, Stevens-Johnson syndrome. The Dizziness was classified as Life-threatening in severity. This necessitated clinical intervention. The current patient status regarding this symptom is 'Not Recovered'. The Stevens-Johnson syndrome was classified as Severe in severity. This necessitated clinical intervention. The documented action was: Prescribed stuff and advised level. The current patient status regarding this symptom is 'Unknown'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. A Naranjo score of 10 was calculated, The assessment concluded the relationship was 'Highly Probable'. Dechallenge/Rechallenge status was noted as: 'Positive dechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. 

</data>
report_id: ADR-2024-108
report_date: '2024-09-20'
patient_details:
  patient_id: ANON-PX-5302
  gender: Female
  relevant_history:
  - asthma
  - anxiety
  age_at_reaction: 29
suspected_drugs:
- drug_name: Warfarin
  dosage: 65mg
  route_of_administration: Oral
  start_date: '2024-07-03'
  indication_for_use: Thromboembolism prevention
- drug_name: Omeprazole
  dosage: 451mg
  route_of_administration: Intramuscular
  start_date: '2024-07-03'
  indication_for_use: Gastroesophageal reflux disease
  drug_class: Proton-pump inhibitor
adverse_reactions:
- symptom_name: Dizziness
  onset_date: '2024-09-10'
  severity: Life-threatening
  outcome: Not Recovered
  intervention_required: true
- symptom_name: Stevens-Johnson syndrome
  onset_date: '2024-09-10'
  severity: Severe
  outcome: Unknown
  intervention_required: true
  intervention_details: Prescribed stuff and advised level.
causality_assessment:
  assessment_conclusion: Highly Probable
  dechallenge_rechallenge: Positive dechallenge
  naranjo_score: 10
reporting_facility: Lee-Rodriguez Medical Center
reporter_type: Pharmacist
