<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2024-357
Date of Submission: 2024-11-26

This report was submitted by a Patient from Adams Group Medical Center concerning patient ANON-PX-8850. The subject is an adult other with a significant medical history including atrial fibrillation, seasonal allergies, osteoarthritis, coronary artery disease. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Sertraline (SSRI) administered via the Topical route at a dosage of 46mg, initiated on 2024-10-24 for Major depressive disorder and discontinued on 2024-11-21.

On approximately 2024-11-18, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Maculopapular Rash, Anaphylaxis, Somnolence, Stevens-Johnson syndrome, Angioedema. The Maculopapular Rash was classified as Mild in severity. This necessitated clinical intervention. The documented action was: Prescribed talk and advised also. The current patient status regarding this symptom is 'Recovered'. The Anaphylaxis was classified as Mild in severity. This necessitated clinical intervention. The documented action was: Prescribed fly and advised war. The current patient status regarding this symptom is 'Fatal'. The Somnolence was classified as Moderate in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovering'. The Stevens-Johnson syndrome was classified as Moderate in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Not Recovered'. The Angioedema was classified as Moderate in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Unknown'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. A Naranjo score of 9 was calculated, The assessment concluded the relationship was 'Highly Probable'. Dechallenge/Rechallenge status was noted as: 'Negative dechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Lot run radio send everybody community. Personal college chair. Truth rule son special nation us.</data>
report_id: ADR-2024-357
report_date: '2024-11-26'
patient_details:
  patient_id: ANON-PX-8850
  gender: Other
  relevant_history:
  - atrial fibrillation
  - seasonal allergies
  - osteoarthritis
  - coronary artery disease
suspected_drugs:
- drug_name: Sertraline
  dosage: 46mg
  route_of_administration: Topical
  start_date: '2024-10-24'
  indication_for_use: Major depressive disorder
  drug_class: SSRI
  end_date: '2024-11-21'
adverse_reactions:
- symptom_name: Maculopapular Rash
  onset_date: '2024-11-18'
  severity: Mild
  outcome: Recovered
  intervention_required: true
  intervention_details: Prescribed talk and advised also.
- symptom_name: Anaphylaxis
  onset_date: '2024-11-18'
  severity: Mild
  outcome: Fatal
  intervention_required: true
  intervention_details: Prescribed fly and advised war.
- symptom_name: Somnolence
  onset_date: '2024-11-18'
  severity: Moderate
  outcome: Recovering
  intervention_required: false
- symptom_name: Stevens-Johnson syndrome
  onset_date: '2024-11-18'
  severity: Moderate
  outcome: Not Recovered
  intervention_required: false
- symptom_name: Angioedema
  onset_date: '2024-11-18'
  severity: Moderate
  outcome: Unknown
  intervention_required: false
causality_assessment:
  assessment_conclusion: Highly Probable
  dechallenge_rechallenge: Negative dechallenge
  naranjo_score: 9
reporting_facility: Adams Group Medical Center
reporter_type: Patient
notes: Lot run radio send everybody community. Personal college chair. Truth rule
  son special nation us.
