<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2024-635
Date of Submission: 2024-11-29

This report was submitted by a Other Healthcare Professional from Hamilton, Johnson and Kelly Medical Center concerning patient ANON-PX-1460. The subject is a 31-year-old male with a significant medical history including osteoarthritis, anxiety. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Lisinopril (ACE inhibitor) administered via the Intravenous route at a dosage of 365mg, initiated on 2024-10-28 for Hypertension with the course ongoing; Atorvastatin (Statin) administered via the Intravenous route at a dosage of 238mg, initiated on 2024-10-28 for Hypercholesterolemia with the course ongoing.

On approximately 2024-10-29, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Somnolence, Headache, Diarrhea. The Somnolence was classified as Life-threatening in severity. This necessitated clinical intervention. The current patient status regarding this symptom is 'Unknown'. The Headache was classified as Mild in severity. This necessitated clinical intervention. The current patient status regarding this symptom is 'Recovering'. The Diarrhea was classified as Moderate in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Not Recovered'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. A Naranjo score of 2 was calculated, The assessment concluded the relationship was 'Possible'. Dechallenge/Rechallenge status was noted as: 'Rechallenge not performed'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Fast clearly really east include. Military social cost two international prevent.</data>
report_id: ADR-2024-635
report_date: '2024-11-29'
patient_details:
  patient_id: ANON-PX-1460
  gender: Male
  relevant_history:
  - osteoarthritis
  - anxiety
  age_at_reaction: 31
suspected_drugs:
- drug_name: Lisinopril
  dosage: 365mg
  route_of_administration: Intravenous
  start_date: '2024-10-28'
  indication_for_use: Hypertension
  drug_class: ACE inhibitor
- drug_name: Atorvastatin
  dosage: 238mg
  route_of_administration: Intravenous
  start_date: '2024-10-28'
  indication_for_use: Hypercholesterolemia
  drug_class: Statin
adverse_reactions:
- symptom_name: Somnolence
  onset_date: '2024-10-29'
  severity: Life-threatening
  outcome: Unknown
  intervention_required: true
- symptom_name: Headache
  onset_date: '2024-10-29'
  severity: Mild
  outcome: Recovering
  intervention_required: true
- symptom_name: Diarrhea
  onset_date: '2024-10-29'
  severity: Moderate
  outcome: Not Recovered
  intervention_required: false
causality_assessment:
  assessment_conclusion: Possible
  dechallenge_rechallenge: Rechallenge not performed
  naranjo_score: 2
reporting_facility: Hamilton, Johnson and Kelly Medical Center
reporter_type: Other Healthcare Professional
notes: Fast clearly really east include. Military social cost two international prevent.
