<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2025-879
Date of Submission: 2025-04-15

This report was submitted by a Physician from Davis, Garcia and Torres Medical Center concerning patient ANON-PX-5949. The subject is an adult male with a significant medical history including seasonal allergies, osteoarthritis, chronic kidney disease. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Ibuprofen (NSAID) administered via the Oral route at a dosage of 121mg, initiated on 2025-01-17 for Pain and inflammation and discontinued on 2025-03-21.

On approximately 2025-01-24, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Headache, Dizziness. The Headache was classified as Moderate in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Unknown'. The Dizziness was classified as Moderate in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Not Recovered'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. A Naranjo score of 7 was calculated, The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Negative dechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. 

</data>
report_id: ADR-2025-879
report_date: '2025-04-15'
patient_details:
  patient_id: ANON-PX-5949
  gender: Male
  relevant_history:
  - seasonal allergies
  - osteoarthritis
  - chronic kidney disease
suspected_drugs:
- drug_name: Ibuprofen
  dosage: 121mg
  route_of_administration: Oral
  start_date: '2025-01-17'
  indication_for_use: Pain and inflammation
  drug_class: NSAID
  end_date: '2025-03-21'
adverse_reactions:
- symptom_name: Headache
  onset_date: '2025-01-24'
  severity: Moderate
  outcome: Unknown
  intervention_required: false
- symptom_name: Dizziness
  onset_date: '2025-01-24'
  severity: Moderate
  outcome: Not Recovered
  intervention_required: false
causality_assessment:
  assessment_conclusion: Probable
  dechallenge_rechallenge: Negative dechallenge
  naranjo_score: 7
reporting_facility: Davis, Garcia and Torres Medical Center
reporter_type: Physician
