<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2025-779
Date of Submission: 2025-03-11

This report was submitted by a Nurse from Smith, Duffy and Miller Medical Center concerning patient ANON-PX-9627. The subject is a 84-year-old other with a significant medical history including coronary artery disease, seasonal allergies, hypertension. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Warfarin (Anticoagulant) administered via the Oral route at a dosage of 496mg, initiated on 2025-01-19 for Thromboembolism prevention and discontinued on 2025-03-07.

On approximately 2025-03-01, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Pruritus, Nausea, Headache. The Pruritus was classified as Severe in severity. This necessitated clinical intervention. The documented action was: Prescribed car and advised suddenly. The current patient status regarding this symptom is 'Recovering'. The Nausea was classified as Life-threatening in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Unknown'. The Headache was classified as Life-threatening in severity. This necessitated clinical intervention. The current patient status regarding this symptom is 'Recovered'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Positive rechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Per military word family rest make put. Themselves conference suffer industry see city. Suddenly act people entire cultural move me.</data>
report_id: ADR-2025-779
report_date: '2025-03-11'
patient_details:
  patient_id: ANON-PX-9627
  gender: Other
  relevant_history:
  - coronary artery disease
  - seasonal allergies
  - hypertension
  age_at_reaction: 84
suspected_drugs:
- drug_name: Warfarin
  dosage: 496mg
  route_of_administration: Oral
  start_date: '2025-01-19'
  indication_for_use: Thromboembolism prevention
  drug_class: Anticoagulant
  end_date: '2025-03-07'
adverse_reactions:
- symptom_name: Pruritus
  onset_date: '2025-03-01'
  severity: Severe
  outcome: Recovering
  intervention_required: true
  intervention_details: Prescribed car and advised suddenly.
- symptom_name: Nausea
  onset_date: '2025-03-01'
  severity: Life-threatening
  outcome: Unknown
  intervention_required: false
- symptom_name: Headache
  onset_date: '2025-03-01'
  severity: Life-threatening
  outcome: Recovered
  intervention_required: true
causality_assessment:
  assessment_conclusion: Probable
  dechallenge_rechallenge: Positive rechallenge
reporting_facility: Smith, Duffy and Miller Medical Center
reporter_type: Nurse
notes: Per military word family rest make put. Themselves conference suffer industry
  see city. Suddenly act people entire cultural move me.
