<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2025-126
Date of Submission: 2025-05-30

This report was submitted by a Patient from Mendez Group Medical Center concerning patient ANON-PX-3045. The subject is an adult male with a significant medical history including seasonal allergies, atrial fibrillation, type 2 diabetes. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Lisinopril (ACE inhibitor) administered via the Intravenous route at a dosage of 132mg, initiated on 2025-04-09 for Hypertension and discontinued on 2025-05-29; Amoxicillin administered via the Topical route at a dosage of 82mg, initiated on 2025-04-09 for Bacterial infection and discontinued on 2025-05-29.

On approximately 2025-05-11, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Somnolence, Pruritus, Headache, Nausea. The Somnolence was classified as Moderate in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Unknown'. The Pruritus was classified as Severe in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovering'. The Headache was classified as Moderate in severity. This necessitated clinical intervention. The current patient status regarding this symptom is 'Recovering'. The Nausea was classified as Life-threatening in severity. This necessitated clinical intervention. The documented action was: Prescribed eight and advised wish. The current patient status regarding this symptom is 'Recovered'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. A Naranjo score of 3 was calculated, The assessment concluded the relationship was 'Possible'. Dechallenge/Rechallenge status was noted as: 'Not applicable'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Rule anything speak prepare sound value past. When home under wrong form save career.</data>
report_id: ADR-2025-126
report_date: '2025-05-30'
patient_details:
  patient_id: ANON-PX-3045
  gender: Male
  relevant_history:
  - seasonal allergies
  - atrial fibrillation
  - type 2 diabetes
suspected_drugs:
- drug_name: Lisinopril
  dosage: 132mg
  route_of_administration: Intravenous
  start_date: '2025-04-09'
  indication_for_use: Hypertension
  drug_class: ACE inhibitor
  end_date: '2025-05-29'
- drug_name: Amoxicillin
  dosage: 82mg
  route_of_administration: Topical
  start_date: '2025-04-09'
  indication_for_use: Bacterial infection
  end_date: '2025-05-29'
adverse_reactions:
- symptom_name: Somnolence
  onset_date: '2025-05-11'
  severity: Moderate
  outcome: Unknown
  intervention_required: false
- symptom_name: Pruritus
  onset_date: '2025-05-11'
  severity: Severe
  outcome: Recovering
  intervention_required: false
- symptom_name: Headache
  onset_date: '2025-05-11'
  severity: Moderate
  outcome: Recovering
  intervention_required: true
- symptom_name: Nausea
  onset_date: '2025-05-11'
  severity: Life-threatening
  outcome: Recovered
  intervention_required: true
  intervention_details: Prescribed eight and advised wish.
causality_assessment:
  assessment_conclusion: Possible
  dechallenge_rechallenge: Not applicable
  naranjo_score: 3
reporting_facility: Mendez Group Medical Center
reporter_type: Patient
notes: Rule anything speak prepare sound value past. When home under wrong form save
  career.
