<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2024-904
Date of Submission: 2024-11-16

This report was submitted by a Nurse from Vargas-Frost Medical Center concerning patient ANON-PX-4747. The subject is a 70-year-old other with a significant medical history including osteoarthritis, chronic kidney disease, migraines. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Ibuprofen (NSAID) administered via the Oral route at a dosage of 183mg, initiated on 2024-10-21 for Pain and inflammation and discontinued on 2024-11-05; Amoxicillin administered via the Subcutaneous route at a dosage of 41mg, initiated on 2024-10-21 for Bacterial infection and discontinued on 2024-11-05.

On approximately 2024-11-02, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Maculopapular Rash, Anaphylaxis, Headache, Pruritus. The Maculopapular Rash was classified as Life-threatening in severity. This necessitated clinical intervention. The documented action was: Prescribed character and advised dream. The current patient status regarding this symptom is 'Recovering'. The Anaphylaxis was classified as Life-threatening in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Not Recovered'. The Headache was classified as Moderate in severity. This necessitated clinical intervention. The documented action was: Prescribed so and advised dinner. The current patient status regarding this symptom is 'Recovering'. The Pruritus was classified as Mild in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Unknown'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. A Naranjo score of 5 was calculated, The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Positive dechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Account religious white international base evidence. Whom close bed fight provide if west. Responsibility enough population economic individual off.</data>
report_id: ADR-2024-904
report_date: '2024-11-16'
patient_details:
  patient_id: ANON-PX-4747
  gender: Other
  relevant_history:
  - osteoarthritis
  - chronic kidney disease
  - migraines
  age_at_reaction: 70
suspected_drugs:
- drug_name: Ibuprofen
  dosage: 183mg
  route_of_administration: Oral
  start_date: '2024-10-21'
  indication_for_use: Pain and inflammation
  drug_class: NSAID
  end_date: '2024-11-05'
- drug_name: Amoxicillin
  dosage: 41mg
  route_of_administration: Subcutaneous
  start_date: '2024-10-21'
  indication_for_use: Bacterial infection
  end_date: '2024-11-05'
adverse_reactions:
- symptom_name: Maculopapular Rash
  onset_date: '2024-11-02'
  severity: Life-threatening
  outcome: Recovering
  intervention_required: true
  intervention_details: Prescribed character and advised dream.
- symptom_name: Anaphylaxis
  onset_date: '2024-11-02'
  severity: Life-threatening
  outcome: Not Recovered
  intervention_required: false
- symptom_name: Headache
  onset_date: '2024-11-02'
  severity: Moderate
  outcome: Recovering
  intervention_required: true
  intervention_details: Prescribed so and advised dinner.
- symptom_name: Pruritus
  onset_date: '2024-11-02'
  severity: Mild
  outcome: Unknown
  intervention_required: false
causality_assessment:
  assessment_conclusion: Probable
  dechallenge_rechallenge: Positive dechallenge
  naranjo_score: 5
reporting_facility: Vargas-Frost Medical Center
reporter_type: Nurse
notes: Account religious white international base evidence. Whom close bed fight provide
  if west. Responsibility enough population economic individual off.
