<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2025-883
Date of Submission: 2025-04-05

This report was submitted by a Physician from Parks LLC Medical Center concerning patient ANON-PX-7208. The subject is a 36-year-old male with a significant medical history including coronary artery disease, chronic kidney disease. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Lisinopril (ACE inhibitor) administered via the Oral route at a dosage of 86mg, initiated on 2025-02-09 for Hypertension with the course ongoing.

On approximately 2025-03-24, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Maculopapular Rash, Diarrhea, Headache, Pruritus, Vomiting. The Maculopapular Rash was classified as Moderate in severity. This necessitated clinical intervention. The current patient status regarding this symptom is 'Fatal'. The Diarrhea was classified as Mild in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Not Recovered'. The Headache was classified as Severe in severity. This necessitated clinical intervention. The documented action was: Prescribed future and advised civil. The current patient status regarding this symptom is 'Recovered'. The Pruritus was classified as Life-threatening in severity. This necessitated clinical intervention. The documented action was: Prescribed east and advised I. The current patient status regarding this symptom is 'Not Recovered'. The Vomiting was classified as Life-threatening in severity. This necessitated clinical intervention. The documented action was: Prescribed policy and advised visit. The current patient status regarding this symptom is 'Unknown'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. A Naranjo score of 7 was calculated, The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Rechallenge not performed'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Treatment only across stuff responsibility. Body recognize few together mean unit material.</data>
report_id: ADR-2025-883
report_date: '2025-04-05'
patient_details:
  patient_id: ANON-PX-7208
  gender: Male
  relevant_history:
  - coronary artery disease
  - chronic kidney disease
  age_at_reaction: 36
suspected_drugs:
- drug_name: Lisinopril
  dosage: 86mg
  route_of_administration: Oral
  start_date: '2025-02-09'
  indication_for_use: Hypertension
  drug_class: ACE inhibitor
adverse_reactions:
- symptom_name: Maculopapular Rash
  onset_date: '2025-03-24'
  severity: Moderate
  outcome: Fatal
  intervention_required: true
- symptom_name: Diarrhea
  onset_date: '2025-03-24'
  severity: Mild
  outcome: Not Recovered
  intervention_required: false
- symptom_name: Headache
  onset_date: '2025-03-24'
  severity: Severe
  outcome: Recovered
  intervention_required: true
  intervention_details: Prescribed future and advised civil.
- symptom_name: Pruritus
  onset_date: '2025-03-24'
  severity: Life-threatening
  outcome: Not Recovered
  intervention_required: true
  intervention_details: Prescribed east and advised I.
- symptom_name: Vomiting
  onset_date: '2025-03-24'
  severity: Life-threatening
  outcome: Unknown
  intervention_required: true
  intervention_details: Prescribed policy and advised visit.
causality_assessment:
  assessment_conclusion: Probable
  dechallenge_rechallenge: Rechallenge not performed
  naranjo_score: 7
reporting_facility: Parks LLC Medical Center
reporter_type: Physician
notes: Treatment only across stuff responsibility. Body recognize few together mean
  unit material.
