<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2024-511
Date of Submission: 2024-12-01

This report was submitted by a Other Healthcare Professional from Sanchez LLC Medical Center concerning patient ANON-PX-1208. The subject is a 22-year-old other with a significant medical history including seasonal allergies, asthma. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Ibuprofen (NSAID) administered via the Subcutaneous route at a dosage of 294mg, initiated on 2024-11-16 for Pain and inflammation and discontinued on 2024-11-25.

On approximately 2024-11-18, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Nausea, Hepatotoxicity, Angioedema. The Nausea was classified as Life-threatening in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Not Recovered'. The Hepatotoxicity was classified as Mild in severity. This necessitated clinical intervention. The current patient status regarding this symptom is 'Not Recovered'. The Angioedema was classified as Moderate in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Unknown'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. A Naranjo score of 3 was calculated, The assessment concluded the relationship was 'Possible'. Dechallenge/Rechallenge status was noted as: 'Positive rechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Kitchen court behind show own play. Adult data magazine specific.</data>
report_id: ADR-2024-511
report_date: '2024-12-01'
patient_details:
  patient_id: ANON-PX-1208
  gender: Other
  relevant_history:
  - seasonal allergies
  - asthma
  age_at_reaction: 22
suspected_drugs:
- drug_name: Ibuprofen
  dosage: 294mg
  route_of_administration: Subcutaneous
  start_date: '2024-11-16'
  indication_for_use: Pain and inflammation
  drug_class: NSAID
  end_date: '2024-11-25'
adverse_reactions:
- symptom_name: Nausea
  onset_date: '2024-11-18'
  severity: Life-threatening
  outcome: Not Recovered
  intervention_required: false
- symptom_name: Hepatotoxicity
  onset_date: '2024-11-18'
  severity: Mild
  outcome: Not Recovered
  intervention_required: true
- symptom_name: Angioedema
  onset_date: '2024-11-18'
  severity: Moderate
  outcome: Unknown
  intervention_required: false
causality_assessment:
  assessment_conclusion: Possible
  dechallenge_rechallenge: Positive rechallenge
  naranjo_score: 3
reporting_facility: Sanchez LLC Medical Center
reporter_type: Other Healthcare Professional
notes: Kitchen court behind show own play. Adult data magazine specific.
