<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2024-993
Date of Submission: 2024-09-09

This report was submitted by a Nurse from Davis, Dennis and Hardy Medical Center concerning patient ANON-PX-6632. The subject is an adult other with a significant medical history including asthma, type 2 diabetes, hypertension, seasonal allergies. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Atorvastatin (Statin) administered via the Subcutaneous route at a dosage of 101mg, initiated on 2024-08-10 for Hypercholesterolemia and discontinued on 2024-09-08; Sertraline administered via the Subcutaneous route at a dosage of 33mg, initiated on 2024-08-10 for Major depressive disorder and discontinued on 2024-09-08.

On approximately 2024-09-07, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Stevens-Johnson syndrome, Maculopapular Rash, Angioedema. The Stevens-Johnson syndrome was classified as Life-threatening in severity. This necessitated clinical intervention. The documented action was: Prescribed manager and advised fish. The current patient status regarding this symptom is 'Unknown'. The Maculopapular Rash was classified as Life-threatening in severity. This necessitated clinical intervention. The current patient status regarding this symptom is 'Not Recovered'. The Angioedema was classified as Severe in severity. This necessitated clinical intervention. The documented action was: Prescribed benefit and advised religious. The current patient status regarding this symptom is 'Fatal'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Not applicable'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Level picture from base exist recently including. Congress as time task success nation. Add upon be lot.</data>
report_id: ADR-2024-993
report_date: '2024-09-09'
patient_details:
  patient_id: ANON-PX-6632
  gender: Other
  relevant_history:
  - asthma
  - type 2 diabetes
  - hypertension
  - seasonal allergies
suspected_drugs:
- drug_name: Atorvastatin
  dosage: 101mg
  route_of_administration: Subcutaneous
  start_date: '2024-08-10'
  indication_for_use: Hypercholesterolemia
  drug_class: Statin
  end_date: '2024-09-08'
- drug_name: Sertraline
  dosage: 33mg
  route_of_administration: Subcutaneous
  start_date: '2024-08-10'
  indication_for_use: Major depressive disorder
  end_date: '2024-09-08'
adverse_reactions:
- symptom_name: Stevens-Johnson syndrome
  onset_date: '2024-09-07'
  severity: Life-threatening
  outcome: Unknown
  intervention_required: true
  intervention_details: Prescribed manager and advised fish.
- symptom_name: Maculopapular Rash
  onset_date: '2024-09-07'
  severity: Life-threatening
  outcome: Not Recovered
  intervention_required: true
- symptom_name: Angioedema
  onset_date: '2024-09-07'
  severity: Severe
  outcome: Fatal
  intervention_required: true
  intervention_details: Prescribed benefit and advised religious.
causality_assessment:
  assessment_conclusion: Probable
  dechallenge_rechallenge: Not applicable
reporting_facility: Davis, Dennis and Hardy Medical Center
reporter_type: Nurse
notes: Level picture from base exist recently including. Congress as time task success
  nation. Add upon be lot.
