<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2024-570
Date of Submission: 2024-11-16

This report was submitted by a Physician from Hooper, Robertson and Davis Medical Center concerning patient ANON-PX-9473. The subject is a 47-year-old male with a significant medical history including asthma, hypertension. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Levothyroxine (Thyroid hormone) administered via the Topical route at a dosage of 299mg, initiated on 2024-09-23 for Hypothyroidism and discontinued on 2024-11-10; Gabapentin (Anticonvulsant) administered via the Subcutaneous route at a dosage of 416mg, initiated on 2024-09-23 for Neuropathic pain and discontinued on 2024-11-10.

On approximately 2024-11-04, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Vomiting, Headache, Maculopapular Rash, Anaphylaxis, Pruritus. The Vomiting was classified as Moderate in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovered'. The Headache was classified as Life-threatening in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovering'. The Maculopapular Rash was classified as Moderate in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovering'. The Anaphylaxis was classified as Severe in severity. This necessitated clinical intervention. The current patient status regarding this symptom is 'Recovered'. The Pruritus was classified as Severe in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Unknown'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Not applicable'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Others state talk wait impact seem life. Provide about live forget our hundred certain. Goal audience behind ever.</data>
report_id: ADR-2024-570
report_date: '2024-11-16'
patient_details:
  patient_id: ANON-PX-9473
  gender: Male
  relevant_history:
  - asthma
  - hypertension
  age_at_reaction: 47
suspected_drugs:
- drug_name: Levothyroxine
  dosage: 299mg
  route_of_administration: Topical
  start_date: '2024-09-23'
  indication_for_use: Hypothyroidism
  drug_class: Thyroid hormone
  end_date: '2024-11-10'
- drug_name: Gabapentin
  dosage: 416mg
  route_of_administration: Subcutaneous
  start_date: '2024-09-23'
  indication_for_use: Neuropathic pain
  drug_class: Anticonvulsant
  end_date: '2024-11-10'
adverse_reactions:
- symptom_name: Vomiting
  onset_date: '2024-11-04'
  severity: Moderate
  outcome: Recovered
  intervention_required: false
- symptom_name: Headache
  onset_date: '2024-11-04'
  severity: Life-threatening
  outcome: Recovering
  intervention_required: false
- symptom_name: Maculopapular Rash
  onset_date: '2024-11-04'
  severity: Moderate
  outcome: Recovering
  intervention_required: false
- symptom_name: Anaphylaxis
  onset_date: '2024-11-04'
  severity: Severe
  outcome: Recovered
  intervention_required: true
- symptom_name: Pruritus
  onset_date: '2024-11-04'
  severity: Severe
  outcome: Unknown
  intervention_required: false
causality_assessment:
  assessment_conclusion: Probable
  dechallenge_rechallenge: Not applicable
reporting_facility: Hooper, Robertson and Davis Medical Center
reporter_type: Physician
notes: Others state talk wait impact seem life. Provide about live forget our hundred
  certain. Goal audience behind ever.
