<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2025-712
Date of Submission: 2025-02-28

This report was submitted by a Physician from Osborn, Reeves and Conner Medical Center concerning patient ANON-PX-5492. The subject is a 34-year-old female with a significant medical history including anxiety, osteoarthritis. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Lisinopril (ACE inhibitor) administered via the Topical route at a dosage of 241mg, initiated on 2025-01-05 for Hypertension with the course ongoing.

On approximately 2025-01-15, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Pruritus, Stevens-Johnson syndrome. The Pruritus was classified as Mild in severity. This necessitated clinical intervention. The documented action was: Prescribed majority and advised pass. The current patient status regarding this symptom is 'Recovering'. The Stevens-Johnson syndrome was classified as Severe in severity. This necessitated clinical intervention. The documented action was: Prescribed clearly and advised marriage. The current patient status regarding this symptom is 'Recovered'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Not applicable'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Price explain use be learn. You white wear send when choice current meeting. Speech drive amount open answer meeting.</data>
report_id: ADR-2025-712
report_date: '2025-02-28'
patient_details:
  patient_id: ANON-PX-5492
  gender: Female
  relevant_history:
  - anxiety
  - osteoarthritis
  age_at_reaction: 34
suspected_drugs:
- drug_name: Lisinopril
  dosage: 241mg
  route_of_administration: Topical
  start_date: '2025-01-05'
  indication_for_use: Hypertension
  drug_class: ACE inhibitor
adverse_reactions:
- symptom_name: Pruritus
  onset_date: '2025-01-15'
  severity: Mild
  outcome: Recovering
  intervention_required: true
  intervention_details: Prescribed majority and advised pass.
- symptom_name: Stevens-Johnson syndrome
  onset_date: '2025-01-15'
  severity: Severe
  outcome: Recovered
  intervention_required: true
  intervention_details: Prescribed clearly and advised marriage.
causality_assessment:
  assessment_conclusion: Probable
  dechallenge_rechallenge: Not applicable
reporting_facility: Osborn, Reeves and Conner Medical Center
reporter_type: Physician
notes: Price explain use be learn. You white wear send when choice current meeting.
  Speech drive amount open answer meeting.
