<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2024-640
Date of Submission: 2024-12-26

This report was submitted by a Physician from Hernandez Inc Medical Center concerning patient ANON-PX-2138. The subject is a 83-year-old male with a significant medical history including osteoarthritis, hypertension, coronary artery disease. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Omeprazole administered via the Topical route at a dosage of 243mg, initiated on 2024-11-07 for Gastroesophageal reflux disease and discontinued on 2024-12-14.

On approximately 2024-12-09, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Diarrhea, Dizziness, Stevens-Johnson syndrome. The Diarrhea was classified as Life-threatening in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Unknown'. The Dizziness was classified as Life-threatening in severity. This necessitated clinical intervention. The documented action was: Prescribed state and advised others. The current patient status regarding this symptom is 'Unknown'. The Stevens-Johnson syndrome was classified as Life-threatening in severity. This necessitated clinical intervention. The current patient status regarding this symptom is 'Unknown'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Positive rechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Tax too home information. Crime difference away create explain might president.</data>
report_id: ADR-2024-640
report_date: '2024-12-26'
patient_details:
  patient_id: ANON-PX-2138
  gender: Male
  relevant_history:
  - osteoarthritis
  - hypertension
  - coronary artery disease
  age_at_reaction: 83
suspected_drugs:
- drug_name: Omeprazole
  dosage: 243mg
  route_of_administration: Topical
  start_date: '2024-11-07'
  indication_for_use: Gastroesophageal reflux disease
  end_date: '2024-12-14'
adverse_reactions:
- symptom_name: Diarrhea
  onset_date: '2024-12-09'
  severity: Life-threatening
  outcome: Unknown
  intervention_required: false
- symptom_name: Dizziness
  onset_date: '2024-12-09'
  severity: Life-threatening
  outcome: Unknown
  intervention_required: true
  intervention_details: Prescribed state and advised others.
- symptom_name: Stevens-Johnson syndrome
  onset_date: '2024-12-09'
  severity: Life-threatening
  outcome: Unknown
  intervention_required: true
causality_assessment:
  assessment_conclusion: Probable
  dechallenge_rechallenge: Positive rechallenge
reporting_facility: Hernandez Inc Medical Center
reporter_type: Physician
notes: Tax too home information. Crime difference away create explain might president.
