<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2025-332
Date of Submission: 2025-06-12

This report was submitted by a Pharmacist from Jones-Summers Medical Center concerning patient ANON-PX-8381. The subject is a 65-year-old other with a significant medical history including coronary artery disease, atrial fibrillation, osteoarthritis. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Omeprazole administered via the Intramuscular route at a dosage of 489mg, initiated on 2025-05-14 for Gastroesophageal reflux disease with the course ongoing.

On approximately 2025-05-24, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Diarrhea, Pruritus, Dizziness, Maculopapular Rash, Hepatotoxicity. The Diarrhea was classified as Life-threatening in severity. This necessitated clinical intervention. The current patient status regarding this symptom is 'Unknown'. The Pruritus was classified as Life-threatening in severity. This necessitated clinical intervention. The documented action was: Prescribed federal and advised speech. The current patient status regarding this symptom is 'Fatal'. The Dizziness was classified as Mild in severity. This necessitated clinical intervention. The current patient status regarding this symptom is 'Recovered'. The Maculopapular Rash was classified as Moderate in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Not Recovered'. The Hepatotoxicity was classified as Life-threatening in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovering'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. A Naranjo score of 3 was calculated, The assessment concluded the relationship was 'Possible'. Dechallenge/Rechallenge status was noted as: 'Not applicable'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Door peace local approach space know. Fast glass within democratic describe exactly. Fire what need great.</data>
report_id: ADR-2025-332
report_date: '2025-06-12'
patient_details:
  patient_id: ANON-PX-8381
  gender: Other
  relevant_history:
  - coronary artery disease
  - atrial fibrillation
  - osteoarthritis
  age_at_reaction: 65
suspected_drugs:
- drug_name: Omeprazole
  dosage: 489mg
  route_of_administration: Intramuscular
  start_date: '2025-05-14'
  indication_for_use: Gastroesophageal reflux disease
adverse_reactions:
- symptom_name: Diarrhea
  onset_date: '2025-05-24'
  severity: Life-threatening
  outcome: Unknown
  intervention_required: true
- symptom_name: Pruritus
  onset_date: '2025-05-24'
  severity: Life-threatening
  outcome: Fatal
  intervention_required: true
  intervention_details: Prescribed federal and advised speech.
- symptom_name: Dizziness
  onset_date: '2025-05-24'
  severity: Mild
  outcome: Recovered
  intervention_required: true
- symptom_name: Maculopapular Rash
  onset_date: '2025-05-24'
  severity: Moderate
  outcome: Not Recovered
  intervention_required: false
- symptom_name: Hepatotoxicity
  onset_date: '2025-05-24'
  severity: Life-threatening
  outcome: Recovering
  intervention_required: false
causality_assessment:
  assessment_conclusion: Possible
  dechallenge_rechallenge: Not applicable
  naranjo_score: 3
reporting_facility: Jones-Summers Medical Center
reporter_type: Pharmacist
notes: Door peace local approach space know. Fast glass within democratic describe
  exactly. Fire what need great.
