<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2025-350
Date of Submission: 2025-07-11

This report was submitted by a Other Healthcare Professional from Hodge, Lopez and Johnson Medical Center concerning patient ANON-PX-2456. The subject is a 76-year-old male with a significant medical history including asthma, osteoarthritis, seasonal allergies. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Metformin administered via the Intramuscular route at a dosage of 402mg, initiated on 2025-06-09 for Type 2 diabetes and discontinued on 2025-06-24.

On approximately 2025-06-23, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Diarrhea, Angioedema. The Diarrhea was classified as Life-threatening in severity. This necessitated clinical intervention. The documented action was: Prescribed decade and advised yard. The current patient status regarding this symptom is 'Recovering'. The Angioedema was classified as Moderate in severity. This necessitated clinical intervention. The documented action was: Prescribed idea and advised kid. The current patient status regarding this symptom is 'Recovering'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Not applicable'. The on-site pharmacist concurred with the assessment during a routine case review. 

</data>
report_id: ADR-2025-350
report_date: '2025-07-11'
patient_details:
  patient_id: ANON-PX-2456
  gender: Male
  relevant_history:
  - asthma
  - osteoarthritis
  - seasonal allergies
  age_at_reaction: 76
suspected_drugs:
- drug_name: Metformin
  dosage: 402mg
  route_of_administration: Intramuscular
  start_date: '2025-06-09'
  indication_for_use: Type 2 diabetes
  end_date: '2025-06-24'
adverse_reactions:
- symptom_name: Diarrhea
  onset_date: '2025-06-23'
  severity: Life-threatening
  outcome: Recovering
  intervention_required: true
  intervention_details: Prescribed decade and advised yard.
- symptom_name: Angioedema
  onset_date: '2025-06-23'
  severity: Moderate
  outcome: Recovering
  intervention_required: true
  intervention_details: Prescribed idea and advised kid.
causality_assessment:
  assessment_conclusion: Probable
  dechallenge_rechallenge: Not applicable
reporting_facility: Hodge, Lopez and Johnson Medical Center
reporter_type: Other Healthcare Professional
