<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2024-727
Date of Submission: 2024-12-23

This report was submitted by a Patient from Cook, Hopkins and Weber Medical Center concerning patient ANON-PX-2771. The subject is a 66-year-old other with a significant medical history including chronic kidney disease, anxiety. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Ibuprofen (NSAID) administered via the Subcutaneous route at a dosage of 215mg, initiated on 2024-11-14 for Pain and inflammation and discontinued on 2024-12-12; Sertraline administered via the Topical route at a dosage of 457mg, initiated on 2024-11-14 for Major depressive disorder and discontinued on 2024-12-12.

On approximately 2024-12-03, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Maculopapular Rash, Stevens-Johnson syndrome, Dizziness. The Maculopapular Rash was classified as Moderate in severity. This necessitated clinical intervention. The current patient status regarding this symptom is 'Fatal'. The Stevens-Johnson syndrome was classified as Life-threatening in severity. This necessitated clinical intervention. The current patient status regarding this symptom is 'Fatal'. The Dizziness was classified as Life-threatening in severity. This necessitated clinical intervention. The current patient status regarding this symptom is 'Unknown'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. A Naranjo score of 8 was calculated, The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Not applicable'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Answer draw share step. Ok want service involve body. Exist set billion since surface.</data>
report_id: ADR-2024-727
report_date: '2024-12-23'
patient_details:
  patient_id: ANON-PX-2771
  gender: Other
  relevant_history:
  - chronic kidney disease
  - anxiety
  age_at_reaction: 66
suspected_drugs:
- drug_name: Ibuprofen
  dosage: 215mg
  route_of_administration: Subcutaneous
  start_date: '2024-11-14'
  indication_for_use: Pain and inflammation
  drug_class: NSAID
  end_date: '2024-12-12'
- drug_name: Sertraline
  dosage: 457mg
  route_of_administration: Topical
  start_date: '2024-11-14'
  indication_for_use: Major depressive disorder
  end_date: '2024-12-12'
adverse_reactions:
- symptom_name: Maculopapular Rash
  onset_date: '2024-12-03'
  severity: Moderate
  outcome: Fatal
  intervention_required: true
- symptom_name: Stevens-Johnson syndrome
  onset_date: '2024-12-03'
  severity: Life-threatening
  outcome: Fatal
  intervention_required: true
- symptom_name: Dizziness
  onset_date: '2024-12-03'
  severity: Life-threatening
  outcome: Unknown
  intervention_required: true
causality_assessment:
  assessment_conclusion: Probable
  dechallenge_rechallenge: Not applicable
  naranjo_score: 8
reporting_facility: Cook, Hopkins and Weber Medical Center
reporter_type: Patient
notes: Answer draw share step. Ok want service involve body. Exist set billion since
  surface.
