<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2025-176
Date of Submission: 2025-02-02

This report was submitted by a Nurse from Kline Ltd Medical Center concerning patient ANON-PX-1639. The subject is a 72-year-old female with a significant medical history including seasonal allergies, type 2 diabetes. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Amoxicillin (Penicillin antibiotic) administered via the Subcutaneous route at a dosage of 318mg, initiated on 2024-11-16 for Bacterial infection and discontinued on 2024-12-21.

On approximately 2024-12-02, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Vomiting, Pruritus, Stevens-Johnson syndrome. The Vomiting was classified as Life-threatening in severity. This necessitated clinical intervention. The documented action was: Prescribed hot and advised media. The current patient status regarding this symptom is 'Recovering'. The Pruritus was classified as Life-threatening in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovered'. The Stevens-Johnson syndrome was classified as Severe in severity. This necessitated clinical intervention. The current patient status regarding this symptom is 'Recovering'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. A Naranjo score of 10 was calculated, The assessment concluded the relationship was 'Highly Probable'. Dechallenge/Rechallenge status was noted as: 'Rechallenge not performed'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Seek she parent. Set power do data too Mr.</data>
report_id: ADR-2025-176
report_date: '2025-02-02'
patient_details:
  patient_id: ANON-PX-1639
  gender: Female
  relevant_history:
  - seasonal allergies
  - type 2 diabetes
  age_at_reaction: 72
suspected_drugs:
- drug_name: Amoxicillin
  dosage: 318mg
  route_of_administration: Subcutaneous
  start_date: '2024-11-16'
  indication_for_use: Bacterial infection
  drug_class: Penicillin antibiotic
  end_date: '2024-12-21'
adverse_reactions:
- symptom_name: Vomiting
  onset_date: '2024-12-02'
  severity: Life-threatening
  outcome: Recovering
  intervention_required: true
  intervention_details: Prescribed hot and advised media.
- symptom_name: Pruritus
  onset_date: '2024-12-02'
  severity: Life-threatening
  outcome: Recovered
  intervention_required: false
- symptom_name: Stevens-Johnson syndrome
  onset_date: '2024-12-02'
  severity: Severe
  outcome: Recovering
  intervention_required: true
causality_assessment:
  assessment_conclusion: Highly Probable
  dechallenge_rechallenge: Rechallenge not performed
  naranjo_score: 10
reporting_facility: Kline Ltd Medical Center
reporter_type: Nurse
notes: Seek she parent. Set power do data too Mr.
