<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2025-123
Date of Submission: 2025-01-13

This report was submitted by a Pharmacist from Price Ltd Medical Center concerning patient ANON-PX-7186. The subject is a 46-year-old male with a significant medical history including seasonal allergies, hypertension, osteoarthritis. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Omeprazole (Proton-pump inhibitor) administered via the Subcutaneous route at a dosage of 335mg, initiated on 2024-10-20 for Gastroesophageal reflux disease and discontinued on 2025-01-06.

On approximately 2024-12-19, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Vomiting, Pruritus, Diarrhea. The Vomiting was classified as Life-threatening in severity. This necessitated clinical intervention. The current patient status regarding this symptom is 'Unknown'. The Pruritus was classified as Severe in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovered'. The Diarrhea was classified as Life-threatening in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Not Recovered'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Positive dechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Simple every value hot. Loss my role success. Rest show with weight popular between.</data>
report_id: ADR-2025-123
report_date: '2025-01-13'
patient_details:
  patient_id: ANON-PX-7186
  gender: Male
  relevant_history:
  - seasonal allergies
  - hypertension
  - osteoarthritis
  age_at_reaction: 46
suspected_drugs:
- drug_name: Omeprazole
  dosage: 335mg
  route_of_administration: Subcutaneous
  start_date: '2024-10-20'
  indication_for_use: Gastroesophageal reflux disease
  drug_class: Proton-pump inhibitor
  end_date: '2025-01-06'
adverse_reactions:
- symptom_name: Vomiting
  onset_date: '2024-12-19'
  severity: Life-threatening
  outcome: Unknown
  intervention_required: true
- symptom_name: Pruritus
  onset_date: '2024-12-19'
  severity: Severe
  outcome: Recovered
  intervention_required: false
- symptom_name: Diarrhea
  onset_date: '2024-12-19'
  severity: Life-threatening
  outcome: Not Recovered
  intervention_required: false
causality_assessment:
  assessment_conclusion: Probable
  dechallenge_rechallenge: Positive dechallenge
reporting_facility: Price Ltd Medical Center
reporter_type: Pharmacist
notes: Simple every value hot. Loss my role success. Rest show with weight popular
  between.
