<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2024-489
Date of Submission: 2024-09-06

This report was submitted by a Other Healthcare Professional from Sanchez-Smith Medical Center concerning patient ANON-PX-8115. The subject is an adult other with a significant medical history including atrial fibrillation, osteoarthritis. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Gabapentin administered via the Subcutaneous route at a dosage of 386mg, initiated on 2024-08-04 for Neuropathic pain and discontinued on 2024-08-22; Levothyroxine (Thyroid hormone) administered via the Topical route at a dosage of 362mg, initiated on 2024-08-04 for Hypothyroidism and discontinued on 2024-08-22.

On approximately 2024-08-07, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Nausea, Anaphylaxis, Dizziness, Headache, Somnolence. The Nausea was classified as Moderate in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Fatal'. The Anaphylaxis was classified as Life-threatening in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Fatal'. The Dizziness was classified as Moderate in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Not Recovered'. The Headache was classified as Moderate in severity. This necessitated clinical intervention. The documented action was: Prescribed six and advised whether. The current patient status regarding this symptom is 'Not Recovered'. The Somnolence was classified as Severe in severity. This necessitated clinical intervention. The current patient status regarding this symptom is 'Unknown'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. A Naranjo score of 7 was calculated, The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Positive dechallenge'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Important television smile instead. Ground by necessary. Office anything worker church.</data>
report_id: ADR-2024-489
report_date: '2024-09-06'
patient_details:
  patient_id: ANON-PX-8115
  gender: Other
  relevant_history:
  - atrial fibrillation
  - osteoarthritis
suspected_drugs:
- drug_name: Gabapentin
  dosage: 386mg
  route_of_administration: Subcutaneous
  start_date: '2024-08-04'
  indication_for_use: Neuropathic pain
  end_date: '2024-08-22'
- drug_name: Levothyroxine
  dosage: 362mg
  route_of_administration: Topical
  start_date: '2024-08-04'
  indication_for_use: Hypothyroidism
  drug_class: Thyroid hormone
  end_date: '2024-08-22'
adverse_reactions:
- symptom_name: Nausea
  onset_date: '2024-08-07'
  severity: Moderate
  outcome: Fatal
  intervention_required: false
- symptom_name: Anaphylaxis
  onset_date: '2024-08-07'
  severity: Life-threatening
  outcome: Fatal
  intervention_required: false
- symptom_name: Dizziness
  onset_date: '2024-08-07'
  severity: Moderate
  outcome: Not Recovered
  intervention_required: false
- symptom_name: Headache
  onset_date: '2024-08-07'
  severity: Moderate
  outcome: Not Recovered
  intervention_required: true
  intervention_details: Prescribed six and advised whether.
- symptom_name: Somnolence
  onset_date: '2024-08-07'
  severity: Severe
  outcome: Unknown
  intervention_required: true
causality_assessment:
  assessment_conclusion: Probable
  dechallenge_rechallenge: Positive dechallenge
  naranjo_score: 7
reporting_facility: Sanchez-Smith Medical Center
reporter_type: Other Healthcare Professional
notes: Important television smile instead. Ground by necessary. Office anything worker
  church.
