<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2025-349
Date of Submission: 2025-04-11

This report was submitted by a Physician from Stephenson-Briggs Medical Center concerning patient ANON-PX-1427. The subject is an adult other with a significant medical history including coronary artery disease, migraines, seasonal allergies. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Ibuprofen (NSAID) administered via the Intramuscular route at a dosage of 28mg, initiated on 2025-03-02 for Pain and inflammation with the course ongoing.

On approximately 2025-04-07, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Stevens-Johnson syndrome, Nausea, Somnolence. The Stevens-Johnson syndrome was classified as Severe in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Unknown'. The Nausea was classified as Severe in severity. This necessitated clinical intervention. The documented action was: Prescribed well and advised standard. The current patient status regarding this symptom is 'Recovering'. The Somnolence was classified as Severe in severity. This necessitated clinical intervention. The documented action was: Prescribed while and advised memory. The current patient status regarding this symptom is 'Not Recovered'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. A Naranjo score of 8 was calculated, The assessment concluded the relationship was 'Probable'. Dechallenge/Rechallenge status was noted as: 'Not applicable'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: Professional fight early discuss. National law fine industry activity black.</data>
report_id: ADR-2025-349
report_date: '2025-04-11'
patient_details:
  patient_id: ANON-PX-1427
  gender: Other
  relevant_history:
  - coronary artery disease
  - migraines
  - seasonal allergies
suspected_drugs:
- drug_name: Ibuprofen
  dosage: 28mg
  route_of_administration: Intramuscular
  start_date: '2025-03-02'
  indication_for_use: Pain and inflammation
  drug_class: NSAID
adverse_reactions:
- symptom_name: Stevens-Johnson syndrome
  onset_date: '2025-04-07'
  severity: Severe
  outcome: Unknown
  intervention_required: false
- symptom_name: Nausea
  onset_date: '2025-04-07'
  severity: Severe
  outcome: Recovering
  intervention_required: true
  intervention_details: Prescribed well and advised standard.
- symptom_name: Somnolence
  onset_date: '2025-04-07'
  severity: Severe
  outcome: Not Recovered
  intervention_required: true
  intervention_details: Prescribed while and advised memory.
causality_assessment:
  assessment_conclusion: Probable
  dechallenge_rechallenge: Not applicable
  naranjo_score: 8
reporting_facility: Stephenson-Briggs Medical Center
reporter_type: Physician
notes: Professional fight early discuss. National law fine industry activity black.
