<format type="yaml">{report_id: string, report_date: date, patient_details: {patient_id: string, age_at_reaction: number optional, gender: string, relevant_history: list[string]}, suspected_drugs: list[{drug_name: string, drug_class: string optional, dosage: string, route_of_administration: string, start_date: date, end_date: date optional, indication_for_use: string}], adverse_reactions: list[{symptom_name: string, onset_date: date, severity: string, outcome: string, intervention_required: boolean, intervention_details: string optional}], causality_assessment: {naranjo_score: number optional, assessment_conclusion: string, dechallenge_rechallenge: string}, reporting_facility: string, reporter_type: string, notes: string optional}</format> <data>PHARMACOVIGILANCE CASE REPORT - CONFIDENTIAL
Report Identifier: ADR-2024-789
Date of Submission: 2024-10-12

This report was submitted by a Other Healthcare Professional from Webster PLC Medical Center concerning patient ANON-PX-7040. The subject is an adult female with a significant medical history including type 2 diabetes, osteoarthritis, asthma, chronic kidney disease. The facility's standard operating procedure for ADR reporting was followed, and all patient data has been anonymized. The patient chart was reviewed for comorbidities. 

Current medication review revealed the following suspected agent(s): Ibuprofen (NSAID) administered via the Topical route at a dosage of 171mg, initiated on 2024-08-09 for Pain and inflammation with the course ongoing.

On approximately 2024-09-17, the patient began to manifest an adverse event. The primary symptoms noted in the clinical log were Dizziness, Pruritus. The Dizziness was classified as Life-threatening in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Not Recovered'. The Pruritus was classified as Severe in severity. No specific therapeutic intervention was required. The current patient status regarding this symptom is 'Recovered'. 

CAUSALITY ASSESSMENT:
An evaluation of causality was performed. A Naranjo score of 9 was calculated, The assessment concluded the relationship was 'Highly Probable'. Dechallenge/Rechallenge status was noted as: 'Not applicable'. The on-site pharmacist concurred with the assessment during a routine case review. 

Reporter's Narrative Summary: You wait else hour. Happy effort network music.</data>
report_id: ADR-2024-789
report_date: '2024-10-12'
patient_details:
  patient_id: ANON-PX-7040
  gender: Female
  relevant_history:
  - type 2 diabetes
  - osteoarthritis
  - asthma
  - chronic kidney disease
suspected_drugs:
- drug_name: Ibuprofen
  dosage: 171mg
  route_of_administration: Topical
  start_date: '2024-08-09'
  indication_for_use: Pain and inflammation
  drug_class: NSAID
adverse_reactions:
- symptom_name: Dizziness
  onset_date: '2024-09-17'
  severity: Life-threatening
  outcome: Not Recovered
  intervention_required: false
- symptom_name: Pruritus
  onset_date: '2024-09-17'
  severity: Severe
  outcome: Recovered
  intervention_required: false
causality_assessment:
  assessment_conclusion: Highly Probable
  dechallenge_rechallenge: Not applicable
  naranjo_score: 9
reporting_facility: Webster PLC Medical Center
reporter_type: Other Healthcare Professional
notes: You wait else hour. Happy effort network music.
