I whanau a Maria Domenica Melone, i uru ia ki nga Franciscan Sisters of Blessed Angela o Foligno (Suore Francescane Angeline i te Itari) i muri i tana paetahi i te kura tuarua. I tangohia e ia tana oati mo te wa poto i te tau 1986, a i whakawhiwhia e ia tana oati pumau i te tau 1991. He maha nga tohu a Melone. He tohu ia mo te whakaako me te rapunga whakaaro mai i te Libera Università Maria SS. Assunta, i puta i te tau 1992. I ako ia i te kaupapa atua i te Whare Wananga o Pontifical Antonianum, i puta i te tau 1996. I whakaotihia e ia tana tohu Doctor of Philosophy (PhD) i te Whare Wananga o Pontifical Antonianum i te tau 2001; ko tana tuhinga tohungatanga ko Te Wairua Tapu i roto i te 'Deinitate' a St. Richard Victor. Mai i te 2011 ki te 2014, ko Melone te Kaiwhakahaere o te Tari o te Papa o te Papa i te Whare Wananga o Antonianum.
Te Whare Wānanga o Pōneke o Antonianum