Whakaoti i te rerenga e whai ake nei: I te 14 o Hōngongoi 2015, i hainatia ia e Cagliari. I awhina ia i te karapu ki te whakatairanga ki Serie A i tana wa.
I te tau tuatahi me te taha, ana ka tiimata tana whakataetae Serie A i te wikitoria 3 <unk> 0 ki a Atalanta, i te 18 o Hepetema 2016 i te tau e whai ake nei; i te mutunga kua tutuki i a ia tana moemoea mo te tamarikitanga ki te purei i te wehenga Itari o runga, i tangi ia i te uiui i muri o te tukinga. I te tau 2016, i whakaingoatia a Pisacane hei toa tuatahi mo te "The Guardian's Footballer of the Year", i whakawhiwhia ki "he kaitakaro kua mahi i tetahi mea tino nui, ahakoa ma te wikitoria i te raru, te awhina i etahi atu, te whakaatu tauira hakinakina ranei ma te mahi pono".