Tirohia te wāhanga i raro nei, kātahi ka whakautu i te pātai i muri mai i te reo kotahi me te wāhanga:  Whakawhiti: I te wā ka whara tuatahi te kiko, ka pā mai te toto ki te collagen, e whakaoho ana i ngā pūmārō o te toto ki te tīmata ki te whakaputa i ngā take mumura. Ka whakaputahia hoki e ngā kōpae toto ngā glycoproteins whakapiri i runga i ō rātou pūtau ārai e āhei ai rātou ki te whakakotahi, ki te waihanga i tētahi papatipu. Ka honoa te fibrin me te fibronectin ki a rāua anō, ā, ka hanga i tētahi kōpae e mau ana i ngā pūmua me ngā matūriki, ā, ka ārai i te ngaronga toto. Ko tēnei pūāhua fibrin-fibronectin hoki te tautoko hanganga matua mō te whara tae noa ki te whakatakoto o te collagen. Ka whakamahia e ngā pūtau manene tēnei kōpaki hei matrix hei kōpaki, ā, ka piri ngā pūmārō ki a ia, ā, ka whakaputa i ngā āhuatanga. I te mutunga ka whakakorehia te kohuke, ka whakakapihia ki te kiko granulation, katahi ka mutu ki te collagen.  Pātai: He aha te mea ka pā atu te toto ki te collagen?
te whakaoho i ngā pūmārō o te toto ki te tīmata ki te whakaputa i ngā take pākia