Tirohia te wāhanga i raro nei, kātahi ka whakautu i te pātai i muri mai i te reo kotahi me te wāhanga:  He matatini te huringa ora o te huaketo hepatitis B. Ko te mate hepatitis B tētahi o ngā pararetroviruses iti e mōhiotia ana: he kore-retroviruses e whakamahi tonu ana i te whakawhitinga whakamuri i roto i ta rātau tukanga tāruatanga. Ka uru atu te huaketo ki roto i te pūtau mā te here ki te NTCP i runga i te mata, ā, ka whakahaeretia. I te mea ka tini haere te huaketo mā te RNA i hangaia e tētahi whākōkī kaihautū, me whakawhiti te DNA huaketo ki te karihi pūtau e ngā pūmua kaihautū e kiia nei ko ngā chaperones. Ko te DNA huaketo takirua takirua kua oti te hanga e te polymerase huaketo, ka hurihia ki te DNA porohita kati (cccDNA). Ko tēnei cccDNA hei tauira mō te tuhi o ngā mRNA huaketo e whā mā te RNA polymerase o te kaihautū. Ko te mRNA nui rawa atu, (he roa ake i te huinga ira huaketo), ka whakamahia hei hanga i nga kape hou o te huaketo me te hanga i te pūmua matua capsid me te DNA polymerase huaketo. Ka tukatukahia anō ēnei tuhinga huaketo e whā, ā, ka haere tonu ki te hanga uri virions ka tukuna mai i te pūtau, ka hoki rānei ki te karihi, ā, ka hurihia hei whakaputa anō i ētahi atu tārua. Ko te mRNA roa ka whakahokia ki te cytoplasm kei reira te pūmua virion P (te DNA polymerase) e whakahiato ana i te DNA ma tana mahi reverse transcriptase.  Pātai: He aha te huaketo kore-retroviruses e whakamahi tonu ana i te whakawhitinga whakamuri i roto i a raatau tukanga whakaputa?
huaketo mate pukupuku B