Ko te tūponotanga o te whakawhanake i te mate he teitei ake i roto i te whanaunga o te tangata e pā ana, ki te he mōrea nui i roto i te hunga e tino tata pā ana. I roto i te rua kotahi e pā ana e rua e pā ana ki 30% o te wa, i te a tawhio noa 5% mo te rua-kore-tinotahi me 2.5% o teina e pā ana ki te he ōrau iti o te hawhe-tuakana. Ki te pāngia e rua matua te mōrea i roto i to ratou tamariki ko 10 nga wa i te o te taupori whānui. MS Ko hoki noa i roto i te tahi mau rōpū iwi atu i ētahi atu. ngā ira motuhake e kua hono ki MS ngā rerekētanga i roto i te hononga o te tangata leukocyte antigen (HLA<unk>a ira i runga i te rōpū 6 chromosome e mahi rite te nuinga o te mate pukupuku ki tona twins rite HLAB). kua whakaaturia hoki i roto i te tahi atu rangahau i te rohe o HLAB, kua kitea hoki i roto i te tau 1980 e kore he rerekētanga ārai i waenganui i te HLA1 me te
Ko te HLA-C554