Whakaotihia te rerenga e whai ake nei: I a Charles V e whakahaere ana i te Diet of Worms, i tukuna e Francis I o France tana rangatira rangatira a Robert de la Marck ki te whakaeke i nga Whenua iti o Burgundian me te tautoko i a Henry II o Navarre i roto i te pakanga ki te whakahoki mai i te Navarre Iberian. I whakautu te Emepara ma te kii kua kore a Francis i a Milan ka hanga i tetahi hononga anti-French me Pope Leo X (8 Mei 1521), e hiahia ana ki te whakauru i nga rohe rautaki o Parma me Piacenza, he waahanga o Milan e puritia ana e nga French. Na, ka tīmata te Pakanga o nga Tau e wha. I taua wa, ka whakapaea a Cortés (Mei 26) ka nohoia (Akuhata 13)
Ko Tenochtictlan, e whakaoti ana i te wikitoria o te Emepaea o Aztec. Ko te kaipuke e kawe ana i te taonga nui o te emepara o Cuauhtémoc i hopukina e te kaiwhaiwhai French a Jean Fleury, engari ko te 120,00 ducats o te koura koura i tae ki te putea Imperial i te wa o te pakanga Itari. I whakaahuatia a Renaissance Italy e Mercurino di Gattinara hei "te turanga matua o te emepaea" me Francis I me Charles V, i whakaarohia ko nga rangatira Pakeha tino kaha o taua wa, i hiahia ki te rangatira i te peninsula taonga. Ka rite ki te kōrero a te Renaissance a Francesco Guicciardini i whakamārama: