Ko te ahua tino noa o te crossover chromosomal ko homologous recombination, te wahi e rua chromosomes whai wāhi faaite raupapa tino rite. Non-homologous recombination taea e kino ki ngā pūtau, no te mea ka taea e te whakaputa i te translocations chromosomal me ngā rerekētanga iranga. Kei te katia te tauhohenga recombination e enzymes mohiotia rite recombinases, pērā i RAD51. Ko te taahiraa tuatahi i roto i te recombination ko te rua-whakaputaina e te tetahi i te mutunga o te nuclease ranei ki te DNA ki te uru. Ka taea e te raupapa o nga kaupae i roto i ia wāhanga o te pūtau i roto i te whakautu ki te whatiwhatiwhati double-strand. Na reira, e taea te whakakorenga i te tahi atu momo o te DNA i roto i te wehenga helicidate, i te tahi atu momo o te DNA i roto i te whatiwhatiwhatiwhati tata, i te tahi atu momo o te DNA i roto i te wehenga helicidate, i roto i te tahi
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