I roto i te 1926, James B. Sumner whakaatu e te urease pūmua ko te pūmua parakore, me te crystallized reira; Sumner i rite hoki mo te catalase pūmua i roto i 1937. te whakatau e taea e pūmua parakore hei pūmua i tino whakamatauria e Northropites ko Stanley, i mahi i runga i te pūmua poke pepsin (1930), trypsin me chymotrypsin. i whakawhiwhia enei pūtaiao e toru te Nobel Prize i roto i te tau 1946. whakaputaina tenei kitenga e taea te whakapā enzymatic ki pūmua, engari tokomaha pūtaiao (pērā i Nobel laureate Richard Willstätter) tohe e pūmua i kawe noa mō te pūmua pono, me e pūmua i roto i te kore i taea o catalysis. Heoi, i roto i te 1926, James B. Sumner whakaaturia e te urease pūmua ko te pūmua parakore, me te crystallized reira; Sumner i rite hoki mo te catalase pūmua i roto i te 1937. i te mutunga e taea e pūmua parakore hei pūmua i tino whakamatauria e Northropites ko Stanley
Ko te Tohu Nobel i roto i te Matū