Whakarāpopototia te tuhinga:  Ko te whakapono ko nga rongoā antidepressant tino rongonui e whakanui ana i nga taumata serotonin i roto i te roro he mea noa iho he korero pakiwaitara, e kii ana tetahi kaiwhakaako rongonui o te hinengaro. Ko David Healy, te tumuaki o te hinengaro i te Hergest psychiatric unit i Bangor, Te Tai Tokerau o Wales, i mea kua whakapumautia te whakaaro hē ko nga taumata iti o te serotonin te kawenga mo te pouri. I whakaaro ia ko te angitu o nga rongoā SSRI e kiia nei ko Prozac me Seroxat i runga i te "hokohoko o te pakiwaitara". Panuku ki raro mō te ataata. Ko te ariā e whakapiki ana i te taumata serotonin i roto i te roro ko te rongoā antidepressant tino rongonui he mea noa iho, e tautohe ana te tohunga hinengaro, a David Healy. Ko te whakaahua ko Prozac, tētahi o ngā SSRI i whakaritea i te nuinga o te wā. Ko te putanga mai o enei raau taero serotonin reuptake (SSRI) i te mutunga o te 1980 i muri i nga awangawanga mo te whakamahinga o te tranquilliser hei whakaora i te pouri. Ahakoa he ngoikore ake rātau i ngā rongoā anti-depressant tricyclic o mua, i piki haere rātau nā te whakaaro e whakahokia ana e ngā SSRI ngā taumata serotonin ki te āhua noa, <unk>he ariā i hurihia ki te ariā e whakatika ana rātau i tētahi korenga matū<unk>. I roto i tētahi tuhinga i roto i te BMJ, ka mea a Healy i ngā tau 1990, kāore he tangata i mōhio mēnā ka whakaarahia, ka whakaitihia rānei e ngā SSRI ngā taumata serotonin, engari kāore he taunakitanga e whakatika ana te maimoatanga i tētahi mea. Ka mea ia: "Mo nga taakuta he mea ngawari ki te whakawhitiwhiti korero ki nga tuuroro. <unk>Mā ngā tūroro, he kaha ā-hinengaro te ariā o te whakatika i tētahi rerekētanga e taea ana te tūmanako kia taea te wikitōria i ngā āwangawanga i ētahi pea e pā ana ki te tango i tētahi rongoā whakamamae, ina koa ka takahia ki roto i te puka ātaahua e kore e ngoikore te raruraru.<unk> Heoi anō, kua whakahē ētahi atu tohunga hinengaro i ngā kerēme a te pouako, e kī ana kua neke atu te mahi i tētahi whakaahuatanga māmā o ngā pire e whakatika ana i tētahi korenga matū. I whakatūpato rātau ka whara pea te tautohetohe ki ngā tūroro pouri mēnā ka ārai rātau i te tango i ngā rongoā, kua whakamatautauria ki te mahi i roto i ngā whakamātautau me te "ao tūturu". Me tautuhi anō te pouri hei mate hopuhopu...
Ko David Healy te tumuaki o te rāngai hinengaro i te tari hinengaro o Hergest i Bangor. E kī ana ko te ariā ko te taumata iti o te serotonin e pā ana ki te pouri he tinihanga. Ko te hokohoko o ngā rongoā SSRI pēnei i te Prozac kua 'hāngai ki runga i te pakiwaitara', e ai ki a ia. E whakahē ana ngā tohunga i ana kerēme e mea ana 'E mahi ana ngā SSRI i te ao tūturu o te whare haumanu'