Tuhia he tohutoro mō tēnei wāhanga - I Rio de Janeiro, e whā ngā mētara i riro i a Adrian. I wikitoria e ia tana mētara tuatahi hei kaikawe mo te reanga 4 × 100 mita koreutu i te taha o Caeleb Dressel, Michael Phelps, me Ryan Held. Ko nga Amerikana, me Dressel me Held hei kaiwhakataetae Olympic tuatahi, i mutu me te waa 3:09.92, i whai mai a France me Ahitereiria. Ko te waewae whakamutunga o Adrian ko 46.97 hēkona, ko te tere rawa o te mara. I tana whakataetae takitahi tuatahi, ko te 100 mita kāhua kore
, I kore a Adrian ki te tiaki i tana taitara Orimipia, i pa ki te tuatoru i muri i a Kyle Chalmers me Pieter Timmers i roto i te 47.85 hēkona. I wikitoria anō a Adrian i tētahi atu mētara parahi i roto i te 50 mita rere noa, i te mutunga i roto i te 21.49 hēkona. Ko tetahi atu Amerikana, ko Anthony Ervin, i wikitoria i roto i te 21.40 hēkona, a ko te toa Olympic o Florent Manadou te tuarua. I whakaotihia e ia tana Olympics me tetahi atu mētara koura i roto i te 4x100 mita medley relay i te ra whakamutunga o te whakataetae, e kaukau ana i te taha o Ryan Murphy, Cody Miller, me Michael Phelps. I whakanohoia e ia te reanga me te 46.74 wehenga ki te kawe mai i te koura ki te 3:27.95, he rekoata Orimipia hou.