Ko te whakatipuranga o te glucose mai i te pūhui rite pyruvate, lactate, glycerol, glycerate 3-phosphate me waikawa amino e kiia gluconeogenesis. Gluconeogenesis tahuri pyruvate ki glucose-6-phosphate i roto i te raupapa o takawaenga, he maha o nei e faaite ki glycolysis. Heoi, e kore e tenei ara glycolysis rere noa i roto i te reverse, rite maha kaupae e catalyzed e enzymes non-glycolytic. He mea nui no te mea e taea ai te hanganga me te whakaheke o te glucose ki te kia whakaritea tika, a e kore e taea te ārai i rua ara i roto i te rere i te huringa pūkoro. Ahakoa ko te reira i te ara pūkoro o te ngako rite pyrruvate, lactate, glycerol, glycerate 3-phosphate me waikawa amino hua i roto i te pūtauira pūtauira, e taea te tahuri te reira i roto i te pūtauira pūtauira i roto i te tinana o te tangata, engari e taea te whakamahi i te reira i roto i te
Me whakaputa e nga vertebrates nga tinana ketone mai i nga waikawa momona hei whakakapi i te huka i roto i nga kiko penei i te roro kaore e taea te whakakotahi i nga waikawa momona