Whakarāpopototia te tuhinga:  Ko te kano ārai mate, e mōhiotia ana ko RTS,S, e 30 tau te roa ki te whakawhanake, engari kei te tūmanakohia inaianei ka taea te whakamahi hei whakaora i te miriona o ngā oranga. E ai ki ngā pūtaiao, ka taea e tētahi werohanga hou ki te mate malaria te ārai i te miriona o ngā mate. E kii ana nga Kairangahau ko te kano kano, kua oti noa i nga waahanga whakamutunga o te whakamatautau, ka taea te "tuku nui" ki te whakahaere i te mate. Kua tono te kamupene rongoā a GlaxoSmithKline ki te raihana mai i te European Medicines Agency (EMA) mo te kano kano RTS,S. He mea nui tēnei rongoā nā te mea ko RTS,S te kano ārai mate malaria tuatahi kua eke ki ngā whakamātautau matatau. I mahia ngā whakamātautau ki runga i ngā kohungahunga me ngā pēpi 15,500 i Āwherika ki te tonga o te Sahara. I roto i te hunga e toru nga horopeta o te RTS,S me te werohanga whakapakari, ko te maha o nga keehi haumanu o te mate malaria <unk> ko era i whakapumautia e te taote <unk> i whakahekehia e 36 ōrau i muri i nga tau e wha. Engari ka ngoikore te tiaki i roto i te wa, he iti ake te mahi o nga kaitautoko i te horopeta tuatahi, a kaore i tino whai hua te kano kano ki nga tamariki nohinohi, e ai ki tetahi purongo i roto i te niupepa The Lancet. Kua neke atu i te 20 tau ngā kaipūtaiao e mahi ana i te kano ārai mate <unk> he nui ake i te £330 miriona te utu, engari e mea ana ngā tohunga he roa te huarahi hei haere. Kāore he kano ārai mate kua whakaaetia ki te mate malaria i te ao katoa, ā, e mea ana ngā kairangahau e tūmanako ana rātou ka nui ngā hua hei whiwhi raihana mā RTS,S mai i te EMA. Ka tūtohu pea te World Health Organization kia whakamahia i te Oketopa o tēnei tau. I roto i ngā whakamātautau, he toharite o ngā take 1,363 o te malaria haumanu i ārai i roto i ngā tau e whā mō ia 1,000 tamariki i werohia, me ngā take 1,774 i roto i te hunga i whiwhi hoki i te booster. I roto i ngā tau e toru, e 558 ngā take i ārai i ia 1,000 ngā kohungahunga i werohia, ā, e 983 ngā take i roto i te hunga i whiwhi anō i te horopeta. E ai ki te Ahorangi Brian Greenwood, te kaituhi o te rangahau, he kaiwhakaako hoki mo te rongoā ā-roto ā-roto i te London School of Hygiene and Tropical Medicine, "Ahakoa te heke haere o te kaha i roto i te wā, he tino painga tonu mai i te RTS,S. <unk>Mā te mea e tata ana ki te 198 miriona ngā take malaria i te tau 2013, ko tēnei taumata o te tōtika...
Ko te kano ārai mate e huaina ana ko RTS,S ka wātea pea hei te Oketopa, e whakapono ana ngā kaipūtaiao. Ka riro hei kano ārai mate tuatahi kua whakaaetia mō te mate tino whakamate o te ao. I hangaia mō te whakamahi i ngā tamariki i Āwherika, ka ārai i te haurua o ngā take. E kii ana nga tohunga he 'whakataetae whakaharahara' mo te kamupene o Ingarangi i whakawhanake i a ia.