I roto i te raumati o 1944 i Cold Spring Harbor Laboratory, McClintock tīmata rangahau pūnaha i runga i te tikanga o te tauira tae mosaic o purapura witi, me te kainga tupu unstable o tenei mosaicism. tā ia te rua hou rangatira, me te taunekeneke loci iranga i huaina e ia Dissociation (Ds) me Activator (Ac). kitea e ia e kore te Dissociation noa dissociate ranei meinga te chromosome ki te pakaru, i reira ano hoki he momo o ngā pānga i runga i ngā ira pātata, i roto i nei i te hanga hoki etahi mutations pūmau unstable. i roto i te tīmatanga o te 1948, i hanga e ia te kitenga faahiahia e taea e rua te whakakotahitanga me te Activator transpose, ranei tūranga, i runga i te chromosome. ka kite ia i te pānga o te whakawhitinga o te Acline me te Ds e te huringa o te tauira o te tae i roto i te mosaic i runga i nga whakatupuranga o te purapura witi, me te kore e taea te wehewehe i te
ngā huānga whakahaere