Ko ētahi atu āhuatanga e taea ai e ngā huakita te wikitōria ārai tinana mā te whakaputa i ngā whākōkī e kōkiri i te arai, hei tauira, mā te whakamahi i te momo II pūnaha secretion. Ka taea hoki, mā te whakamahi i te momo III pūnaha secretion, tāpiri ratou i te ngongo ngongo i roto i te pūtau, te whakarato i te ara tika mō pūmua ki te neke i te pathogen ki te pūtau host. E whakamahia ana ēnei pūmua ki te kati i te defenses host. He rautaki evasion whakamahia e te maha pathogens ki te karo i te pūnaha ārai tinana tūturu ko ki te huna i roto i te pūtau o ratou host (i huaina hoki pathogens intracellular). konei, he pathogenic sponges o ona pūtau mate-wāhi angitu, i te wā i te mawhiti i te kitenga ranei whakangaromanga e te pūnaha ārai mate. Ko ētahi atu tauira o te pūnaha ārai mate-whakamātautau e tiaki ia ratou i roto i te ora pūtau, ko te tiaki ārai i te mate i roto i ngā pūtau, hei tauira
ngā pūtau ārai mate, ngā antibody me te tāpiri