Tirohia te wāhanga i raro nei, kātahi ka whakautu i te pātai i muri mai i te reo kotahi me te wāhanga:  Passage: Ko nga nucleases nga whākōkī e tapahi ana i nga aho DNA ma te whakaoho i te waipiro o nga hononga phosphodiester. Ko ngā nucleases e whakawai ana i ngā nucleotides mai i ngā pito o ngā aho DNA e kiia ana ko ngā exonucleases, i te wā e tapahia ana e ngā endonucleases i roto i ngā aho. Ko ngā karihi e whakamahia nuitia ana i roto i te koiora rāpoi ko ngā karihi ārai, e tapahi ana i te DNA i ngā raupapa motuhake. Hei tauira, ko te whākōkī EcoRV e whakaaturia ana ki te taha mauī e mōhio ana ki te raupapa 6-pūtake 5′-GATATC-3′, ā, ka tapahi i te raina whakapae. I te taiao, ka tiakina e ēnei whākōkī ngā huakita i te mate huaketo mā te kōpeke i te DNA huaketo ina tomo ki te pūtau huaketo, e mahi ana hei wāhanga o te pūnaha whakarerekētanga herenga. I roto i te hangarau, ka whakamahia ēnei karihi raupapa motuhake i roto i te tāruatanga rāpoi ngota me te tātaritanga maihao DNA.  Pātai: He aha te momo o te macromolecule koiora ko nucleases?
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