Tirohia te wahi i raro nei, a ka whakahoki i te pātai i muri i roto i te reo ano rite te wahi: Passage: GH whakaongaonga hoki, i roto i te ara tohu JAK-STAT, te hanga o te āhuatanga tupu insulin-rite 1 (IGF-1, i mohiotia i mua rite somatomedin C), he hormone homologous ki proinsulin. Ko te ate ko te pūhui whāinga nui o GH mo tenei tukanga, me te te wahi matua o te IGF-1 production. IGF-1 kua tupu-whakaongaonga pānga i runga i te whānui o ngā momo o kiko. Kei te hangaia anō IGF-1 i roto i kiko ūnga, hanga te reira te mea e puta ki te kia e rua he hormones endocrine me te autocrine / paracrine. IGF-1 hoki kua pānga whakaongaonga i runga i osteoblast me chondrocyte mahi ki te tupu wheua.I tua atu ki te whakanui ake i te teitei i roto i ngā tamariki me ngā taiohi, he maha atu pānga hormone tupu i runga i te tinana: Pātai: He aha te mea he pānga simulatory?
Ko te IGF-1