Tirohia te wāhanga i raro nei, kātahi ka whakautu i te pātai i muri mai i te reo kotahi me te wāhanga:  Passage: I te mea he mea nui te whakahaere i te mahi whākōkī mo te homeostasis, ko te mahi kino (mutation, overproduction, underproduction or deletion) o te whākōkī nui kotahi ka arahi ki te mate iranga. Ko te ngoikoretanga o te kotahi noa iho o nga momo whākōkī i roto i nga mano o nga momo kei roto i te tinana o te tangata ka mate. He tauira o te mate iranga mate na te ngoikoretanga o te whākōkī ko te mate o Tay<unk>Sachs, kei reira nga tuuroro e ngaro ana i te whākōkī hexosaminidase. Ko tetahi tauira o te ngoikoretanga whākōkī ko te momo phenylketonuria tino noa. He maha nga momo momo waikawa amino kotahi i roto i te whākōkī phenylalanine hydroxylase, e whakaoho ana i te taahiraa tuatahi i roto i te whakaheke o te phenylalanine, ka hua ki te kohinga o te phenylalanine me nga hua e pa ana. Ko etahi o nga huringa kei roto i te waahi kaha, e whakararu tika ana i te here me te catalysis, engari he maha kei tawhiti atu i te waahi kaha, ka whakaiti i te mahi ma te whakakorikori i te hanganga o te pūmua, te awe ranei i te oligomerisation tika. Ka arahina tēnei ki te hauā hinengaro mēnā kāore i rongoatia te mate. Ko tetahi atu tauira ko te ngoikoretanga pseudocholinesterase, i reira ka ngoikore te kaha o te tinana ki te pakaru i nga raau taero choline ester.  Pātai: He aha te ingoa o te āhua hauora kahore he mate?
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