Tirohia te wāhanga i raro nei, kātahi ka whakautu i te pātai i muri mai i te reo kotahi me te wāhanga:  Passage: Ka tīmata te waihanga de novo o te ceramide ki te kōpeketanga o te palmitate me te serine ki te hanga 3-keto-dihydrosphingosine. Ko tēnei tauhohenga e whakapakarihia ana e te whākōkī serine palmitoyl transferase, ā, ko ia te taahiraa whakaiti-tere o te ara. I tua atu, ka whakaitihia te 3-keto-dihydrosphingosine ki te dihydrosphingosine, ka whai ake i te acylation e te whākōkī (dihydro)ceramide synthase ki te whakaputa dihydroceramide. Ko te tauhohenga whakamutunga ki te whakaputa i te ceramide ka whakahiatohia e te dihydroceramide desaturase. Ka puta te whakahiato De novo o te ceramide i roto i te reticulum endoplasmic. I muri mai ka kawea te ceramide ki te taputapu Golgi ma te hokohoko vesicular, ma te pūmua whakawhiti ceramide CERT ranei. I te wa i roto i te taputapu Golgi, ka taea te whakakotahi i te ceramide ki etahi atu sphingolipids, penei i te sphingomyelin me nga glycosphingolipids matatini.  Pātai: He aha te mea i hangaia ai te dihydroceramide
(dihydro) ceramide synthase (dihydro) ceramide synthase) i te tīmatanga