Tirohia te wāhanga i raro nei, kātahi ka whakautu i te pātai i muri mai i te reo kotahi me te wāhanga:  Te rerenga: Ko nga rongoā whakamamae he momo rongoā e whakamahia whānuitia ana hei whakaora i te mamae. Kei roto ko te aspirin me ētahi atu rongoā anti-inflammatory non-steroidal (NSAIDs), tae atu ki te paracetamol antipyretics (e mohiotia ana ko te acetaminophen i te United States) me te phenacetin. I whakauruhia i te mutunga o te rautau 19, ko te phenacetin tetahi waahanga noa o nga rongoa rongoa i nga waahanga o Uropi, Ahitereiria, me te United States. I roto i nga tau 1950, i ripoatahia e Spühler me Zollinger he hononga i waenga i te whara o te whatukuhu me te whakamahinga roa o te phenacetin. I kite rātau he nui ake te tūponotanga o ngā kaiwhakamahi o te phenacetin ki te whakawhanake i ngā whara o te whatukuhu, arā, te nekoro papiri papiri me te nephritis interstitial tawhito. I tapaina tēnei āhuatanga ko te nephropathy analgesic, ā, i whakawhiwhia ki te phenacetin, ahakoa kāore i whakaaturia he wāhi tino take. Na te maha atu o nga ripoata mo te kaha o te whara o te whara ki te whakamahinga roa me te nui o te phenacetin, i aukatihia te phenacetin i roto i nga whenua maha i waenga i nga tau 1960 me te 1980.I te heke o te whakamahinga o te phenacetin, ka heke ano hoki te maha o nga nephropathy analgesic hei take o te mate pukupuku mutunga. Hei tauira, i whakaaturia e ngā raraunga mai i Huitene he hekenga o te horapa o te nephropathy mamae i roto i te hunga mate pukupuku mutunga, mai i te 28% i te 1981 ki te 12% i te 1990. He rangahau whakamomori i mahia i Switzerland i tohu ko te horapa o te nephropathy analgesic i roto i te taupori whānui kua heke iho; ko te horapa ko 3% i 1980 me te 0.2% i 2000. Ahakoa ko enei raraunga e whakaatu ana kua tino whakakorea te nephropathy analgesic i etahi rohe, i etahi atu rohe kei te mau tonu te ahuatanga. Ko te mea nui, i Belgium, ko te horapa o te nephropathy analgesic i roto i nga tangata e whai ana i te dialysis ko te 17.9% i te 1984 me te 15.6% i te 1990. E kī ana a Michielsen rāua ko de Schepper kei te mau tonu te mate pukupuku mā te mamae i roto i ngā tāngata i Belgium e whai ana i te dialysis ehara i te mea nā...  Pātai: He aha te momo o te akomanga tarukino he haunga o te aspirin?
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