Ko ngā pūmua e tohuhia ana mō te whakaheke me te pūmua iti e kiia nei ko te ubiquitin. Ko te urupare tohu e whakaohohia ana e ngā whākōkī e kiia nei ko te ubiquitin ligases. Ka oti te tohu i tētahi pūmua ki tētahi rāpoi ngota o te ubiquitin, he tohu tēnei ki ētahi atu rāpoi ngota ki te hono atu i ētahi atu rāpoi ngota o te ubiquitin. Ko te hua he mekameka polyubiquitin e herea ana e te proteasome, e āhei ana ki te whakaheke i te pūmua kua tohua. Ko te tukanga whakaheke e hua ana i ngā peptides o te whitu ki te waru waikawa amino roa, ka taea te whakaheke atu ki ngā raupapa waikawa amino poto, ka whakamahia ki te waihanga pūmua hou.
ngā rākau ubiquitin