ere is no mention of ethics review, IRB review, or consent of the healthy volunteers. <br />
The abstract from the original manuscript: <br />
There are no discernible quantitative differences in the biotransformation and the excretion of indomethacin following oral, rectal, and intravenous administration of indomethacin-2-^14^C. Approximately 50% (range 24-115% for n = 6) of an intravenous dose undergoes enterohepatic circulation. Thus the bioavailability of indomethacin to the systemic circulation may exc