 title="" class="an ">&ensp;</span>channels <span  title="" class="an ">&ensp;</span>expressed <span  title="" class="an ">&ensp;</span>singly <span  title="" class="an ">&ensp;</span>Moreover <span  title="" class="an ">&ensp;</span>suggesting <span  title="" class="an ">&ensp;</span>electrostatic <span  title="" class="an ">&ensp;</span>interactions <span  title="" class="an ">&ensp;</span>charge <span  title="" class="an ">&ensp;</span>neutralization <span  title="" class="an ">&ensp;</span>mutations <sp