omics.com/target-enrichment/">Hybridization based enrichment</a>. This includes a variety of widely used methods that we will broadly categorize in two groups: Array-based and In-solution:
- <a href="https://en.wikipedia.org/wiki/Exome_sequencing#:~:text=Target%2Denrichment%20strategies-,Array%2Dbased%20capture,-In%2Dsolution%20capture">Array-based capture</a> uses microarrays that have probes designed to bind to known coding sequences. Fragments that do not bind to these probes are washed away, leaving the