 Not necessarily a "right" answer
 
???

- Benefit/harm trade-offs
- Ethics of randomization
- Failed randomization
  - Protocol failure
  - People responding to random assignment by seeking outside interventions
- Deception
  - Omission
  - Commission
- Attrition
- Cross-over
- Informed consent
- Children
- Prisoners
- Cancer patients
- Discontinuing a study early
  - Effective versus ineffective treatment
- Pretreatment
- Preferences over treatments
- Subject pool contamination
- Interference/SUTVA violat