ally intensive models is also provided, and can be used with high performance computing systems in a simple manner, including the capability to restart an unfinished optimisation for models with a long runtime.</p>
<p>It implements generic functions that can be used for fitting any type of models, especially those with non-differentiable objective functions, with the same syntax as base::optim. It supports multiple phases estimation (sequential parameter masking), constrained optimization (bounding box rest