tion of the reference allele to the allelic composition of the tumor and normal tissue at each genomic locus.
- <a href="https://github.com/walaj/svaba">SvABA</a> This tool is especially useful for calling insertions and deletions (indels) because it assembles aberrantly aligned sequence reads that reflect indels or structural variants using a custom <a href="https://github.com/jts/sga">String Graph Assembler</a>. Indels can be difficult to detect with standard alignment-based variant callers.
- <a href="ht