chnology, bacterial projects with 20,000 to 200,000 reads could easily be assembled on one computer. Larger projects, like the human genome with approximately 35 million reads, needed large computing farms and distributed computing.</p>
<p>By 2004 / 2005, <a href="//en.wikipedia.org/wiki/Pyrosequencing" title="Pyrosequencing">pyrosequencing</a> had been brought to commercial viability by <a href="//en.wikipedia.org/wiki/454_Life_Sciences" title="454 Life Sciences">454 Life Sciences</a>. This new sequencing 