</dt><dd><p>if True, use first moment of U and S to run regression</p>
</dd>
<dt>method: <cite>str</cite> (default: Ridge)</dt><dd><p>regression method, choose between Linear, Ridge or Lasso</p>
</dd>
<dt>alpha: <cite>float</cite> (default: 1)</dt><dd><p>regularization coefficient for Ridge and Lasso</p>
</dd>
<dt>beta: <cite>float</cite> (default: 1)</dt><dd><p>mRNA splicing rate constant</p>
</dd>
<dt>rescale: <cite>Bool</cite> (default: True)</dt><dd><p>if True, center counts on zero (default= True). res