t><dd><p>regularization coefficient for Ridge and Lasso</p>
</dd>
<dt>beta: <cite>float</cite> (default: 1)</dt><dd><p>mRNA splicing rate constant</p>
</dd>
<dt>rescale: <cite>Bool</cite> (default: True)</dt><dd><p>if True, center counts on zero (default= True). rescale=True enforces fit_int=False</p>
</dd>
<dt>nsim: <cite>int</cite> (default: 10)</dt><dd><p>number of independent regressions per cluster</p>
</dd>
<dt>frac: <cite>float</cite> (default: 0.9)</dt><dd><p>fraction of cells to randomly select (bo