re electrically inert with no
gap-junctional coupling. The simulation predicts that changes in gap
junction coupling conductance can influence the configuration of
cardiac action potential and cardiomyocyte excitability. I(K(Ca)) can
be elicited by simulated action potential waveforms of cardiac
fibroblasts when they are electrically coupled to cardiomyocytes. This
study demonstrates that a BK(Ca) channel is functionally expressed in
human cardiac fibroblasts. The activity of these BK(Ca) channels
present i