n</a>.
Prometheus instances that are deployed locally to each cluster by Istio act as initial collectors that then federate up
to a production mesh-wide Prometheus instance. That mesh-wide Prometheus can either live outside of the mesh (external), or in one
of the clusters within the mesh.</p><h2 id=multicluster-istio-setup>Multicluster Istio setup</h2><p>Follow the <a href=/v1.14/docs/setup/install/multicluster/>multicluster installation</a> section to setup your Istio clusters in one of the
supported <a h