sequence-data-to-a-reference-genome-and-associated-steps.html">This bioinformatics resource</a> provides a great overview of genome alignment.
- The depth of coverage for sequencing is an important consideration. The typical recommendation for WGS coverage is 30x, but this is on the lower side and many researchers find it does not provide sufficient coverage compared to 50x. Illumina has an <a href="https://www.illumina.com/content/dam/illumina-marketing/documents/techniques/wgs-wes-infographic-web.pdf">inf