f="//en.wikipedia.org/wiki/Post-transcriptional_modification" title="Post-transcriptional modification">post-transcriptional modification</a>.</p>
<h2><span class="mw-headline" id="De-novo_vs._mapping_assembly">De-novo vs. mapping assembly</span></h2>
<p>In sequence assembly, two different types can be distinguished:</p>
<ol>
<li>de-novo: assembling short reads to create full-length (sometimes novel) sequences (see <a href="//en.wikipedia.org/wiki/De_novo_transcriptome_assembly" title="De novo transcriptome