ples to normal and filtering functions for samples with orientation bias artifacts (FFPE samples) called F1R2, which is explained in the link above.
- <a href="https://varscan.sourceforge.net/">Varscan 2</a> This is a helpful tool that utilizes a heuristic/statistic approach to variant calling. This means that it detects somatic CNAs (SCNAs) as deviations from the log-ratio of sequence coverage depth within a tumor–normal pair, and then quantify the deviations statistically. This approach is unique becaus