INK is recommended.</p></li>
<li><p><strong>Coalescent approaches</strong>: Coalescent methods simulate genealogical events backward in time. These events typically include the coalescence of two sequences into a single ancestral lineage, recombination within a sequence or migration between populations. A coalescent-based approach to simulate whole genome data is implemented in GENOME <span class="citation">[2]</span> and its output format is supported as an input format for PhenotypeSimulator.</p></li>
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