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<h3 id="restricted-maximum-likelihood-estimation">Restricted Maximum Likelihood Estimation<a class="anchor" aria-label="anchor" href="#restricted-maximum-likelihood-estimation"></a></h3>


<p>When fitting models with the <code><a href="rma.uni.html">rma.uni</a></code> and <code><a href="rma.mv.html">rma.mv</a></code> functions, use of restricted maximum likelihood (REML) estimation is generally recommended. This is also the default setting (i.e., <code>method="REML"</code>). Various simulation studies ha