p;</span>The <span  title="" class="an ">&ensp;</span>significance <span  title="" class="an ">&ensp;</span>of <span  title="" class="an ">&ensp;</span>these <span  title="" class="an ">&ensp;</span>developmental <span  title="" class="an ">&ensp;</span>variations <span  title="" class="an ">&ensp;</span>in <span  title="" class="an ">&ensp;</span>channel <span  title="" class="an ">&ensp;</span>properties <span  title="" class="an ">&ensp;</span>is <span  title="" class="an ">&ensp;</span>discussed 
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