&ensp;</span>They <span  title="" class="an ">&ensp;</span>were <span  title="" class="an ">&ensp;</span>activated <span  title="" class="an ">&ensp;</span>by <span  title="" class="an ">&ensp;</span>a <span  title="" class="an ">&ensp;</span>non <span  title="" class="an ">&ensp;</span>hydrolysable <span  title="" class="an ">&ensp;</span><span  title="CAP" class="an CAP">PIP</span><span  title="" class="an ">&ensp;</span>analogue <span  title="" class="an ">&ensp;</span>and <span  title="" class="an ">&en