nterim analysis: the alpha spending function approach</span>.” <em>Stat Med</em> 13 (13-14): 1341–52. <a href="https://doi.org/10.1002/sim.4780131308" class="external-link uri">https://doi.org/10.1002/sim.4780131308</a>.
</div>
</div>
</div>
</div>

  </main><aside class="col-md-3"><div class="links">
<h2 data-toc-skip>Links</h2>
<ul class="list-unstyled">
<li><a href="https://cloud.r-project.org/package=GroupSeq" class="external-link">View on CRAN</a></li>
<li><a href="https://github.com/rpahl/GroupSeq