Help Treat the Hardest Things</FONT></B>

<P>At any moment in a given field certain problems, tasks, questions, methods,
phenomena, domains, unmet needs, goals, concepts, subfields, etc explicitly
or implicitly exist that are the most difficult ones of all in that field;
and a subset of these things will be the hardest things in human knowledge
and endeavor as a whole.

<P><U>Breakthroughs in these cases are apt to</U> cause the greatest excitement,
have the largest consequences for those fields or for civi