"external-link">Urbut et
al.</a>, which we strongly recommend reading before proceeding.</p>
<p>In this first vignette we use only the “canonical” covariance matries
to simplify presentation. However, an important aspect of
<code>mashr</code> is the use of data-driven covariance matrices that
are learned from the data, so when you are done here you should look at
<a href="intro_mash_dd.html">the data-driven vignette</a> and the <a href="simulate_noncanon.html">non-canonical matrix vignette</a>. If you
t