 no third trial is performed and the drug development development program is not successful.
In the utility function, this will lead to a utility of -9999.

"><meta property="og:description" content="The function EPsProg23() calculates the expected probability of a successful program
in a time-to-event setting. This function follows a special decision rule in order to determine
whether two or three phase III trials should be conducted. First, two phase III trials are performed. Depending
on their success, t