fier of a particular specimen; and would be a direct identifier of a particular patient. 
This is a ramification of having the specimen identifier. 
One solution is to create pseudo specimen resources that will stand-in for the original specimen resource. 
This pseudo specimen management is supplied by a trusted-third-party that maintains a database of pseudo-identifiers with authorized reversibility.
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Care should be taken when modifying an isModifier elements, as the modification will change the mea