DNA replication
DNA replication proteins

At the replication fork, many replication enzymes assemble on the DNA into a complex molecular machine called the replisome. The following is a list of major DNA replication enzymes that participate in the replisome:

In vitro single-molecule experiments (using optical tweezers and magnetic tweezers) have found synergetic interactions between the replisome enzymes (helicase, polymerase, and Single-strand DNA-binding protein) and with the DNA replication fork enhancing DNA-unwinding and DNA-replication. These results lead to the development of kinetic models accounting for the synergetic interactions and their stability.
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