Catherine de' Medici
Issue

Catherine de' Medici married Henry, Duke of Orléans, the future Henry II of France, in Marseille on 28 October 1533. She gave birth to ten children, of whom four sons and three daughters survived to marriageable age. Three of her sons became kings of France, while two of her daughters married kings and one married a duke. Catherine outlived all her children except Henry III, who died seven months after her, and Margaret, who inherited her robust health. Victoire and Jeanne were twin daughters born in 1556; Jeanne was stillborn due to surgeons breaking her legs to save her mother's life; Victoire survived, dying less than two months later. According to the diplomat Simon Renard, the birth nearly killed Catherine, and the royal couple were advised by the King's physician to have no further children.
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