Cali
Founding and colonial period

The founder of Cali, Sebastián de Belalcázar, came to the American continent in the third voyage made by Columbus in 1498. In 1532, after serving in Darién and Nicaragua, he joined Francisco Pizarro in the conquest of Perú. In 1534, Belalcázar separated from Pizarro's expedition to find the city of Quito, and later in his search of El Dorado he entered the territory of what is now Colombia, founding the cities of Pasto and Popayán.

Belalcázar founded Santiago de Cali on 25 July 1536, a few kilometres north of its present location, near what are now the towns of Vijes and Riofrío. Under the orders of Belalcázar, captain Miguel Muñoz moved the city to its present location in 1537, where the chaplain Brother Santos de Añasco celebrated a mass in the place occupied by the Church La Merced today, and Belalcázar designated Pedro de Ayala as the first municipal authority.

During the Colonia (colonial period), Santiago de Cali was part of the gobernación of Popayán, which was part of Quito 's Audiencia. Although initially Cali was the capital of Popayán's gobernación, Belalcázar moved this function to Popayán in 1540, owing to "better" weather there.

Until the 18th century, most of the territory of what is now Santiago de Cali was occupied by haciendas (cattle farms and plantations of food, with some sugar cane), and the city was only a small town near the Cali River. In 1793, Santiago de Cali had 6,548 inhabitants, 1,106 of whom were (African) slaves. The haciendas were the property of the dominant noble class with many slaves dedicated mostly to stockbreeding and raising sugar cane crops. Many of these haciendas became zone of the present city like Cañaveralejo, Chipichape, Pasoancho, Arroyohondo, Cañasgordas, Limonar and Meléndez. Santiago de Cali was strategically positioned for trade, centrally located in relation to the mining regions of Antioquia, Chocó, and Popayán. The first trail for mules and horses between Santiago de Cali and the port of Buenaventura was completed in the colonial period.
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