Margaret Sanger
American Birth Control League

After World War I, Sanger shifted away from radical politics, and she founded the American Birth Control League (ABCL) in 1921 to enlarge her base of supporters to include the middle class. The founding principles of the ABCL were as follows:

We hold that children should be (1) Conceived in love; (2) Born of the mother's conscious desire; (3) And only begotten under conditions which render possible the heritage of health. Therefore we hold that every woman must possess the power and freedom to prevent conception except when these conditions can be satisfied.

After Sanger's appeal of her conviction for the Brownsville clinic secured a 1918 court ruling that exempted physicians from the law prohibiting the distribution of contraceptive information to women (provided it was prescribed for medical reason), she established the Clinical Research Bureau (CRB) in 1923 to exploit this loophole. The CRB was the first legal birth control clinic in the United States, staffed entirely by female doctors and social workers. The clinic received extensive funding from John D. Rockefeller Jr. and his family, who continued to make anonymous donations to Sanger's causes in subsequent decades.

John D. Rockefeller Jr. donated five thousand dollars to her American Birth Control League in 1924 and a second time in 1925.

In 1922, Sanger traveled to China. In China, she observed that the primary method of family planning was female infanticide, and she later worked with Pearl Buck to establish a family planning clinic in Shanghai. Her visit fueled the belief among elites in Nationalist-era China that the use of contraception would improve the "quality" of the Chinese people and resulted in many newspaper articles addressing the benefits and shortcomings of birth control. Also following Sanger's visit, a wide range of texts on birth control and population issues were imported into China. Chinese feminists inspired by Sanger's visit went on to be significantly involved in the subsequent Chinese debates on birth control and eugenics. Sanger introduced Carbizone birth control tablets to China. During the visit, Sanger encouraged the use of female birth control in part because of her view that frequent use of condoms or the withdrawal method would cause men to develop nervous disorders.

Sanger also visited Korea and Japan. Sanger ultimately visited Japan six times, working with Japanese feminist Kato Shidzue to promote birth control.

In 1928, conflict within the birth control movement leadership led Sanger to resign as the president of the ABCL and take full control of the CRB, renaming it the Birth Control Clinical Research Bureau (BCCRB), marking the beginning of a schism that would last until 1938.

Sanger invested a great deal of effort communicating with the general public. From 1916 onward, she frequently lectured (in churches, women's clubs, homes, and theaters) to workers, churchmen, liberals, socialists, scientists, and upper-class women. She once lectured on birth control to the women's auxiliary of the Ku Klux Klan in Silver Lake, New Jersey. In her autobiography, she justified her decision to address them by writing "Always to me any aroused group was a good group," meaning that she was willing to seek common ground with anyone who might help promote legalization and awareness of birth-control. She described the experience as "weird" and reported that she had the impression that the audience were all half-wits, and, therefore, spoke to them in the simplest possible language, as if she were talking to children.

She wrote several books in the 1920s which had a nationwide impact in promoting the cause of birth control. Between 1920 and 1926, 567,000 copies of Woman and the New Race and The Pivot of Civilization were sold. She also wrote two autobiographies designed to promote the cause. The first, My Fight for Birth Control, was published in 1931 and the second, more promotional version, Margaret Sanger: An Autobiography, was published in 1938.

During the 1920s, Sanger received hundreds of thousands of letters, many of them written in desperation by women begging for information on how to prevent unwanted pregnancies. Five hundred of these letters were compiled into the 1928 book, Motherhood in Bondage.
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