Multiple sclerosis
Special courses

Independently of the types published by the MS associations, regulatory agencies such as the FDA often consider special courses, trying to reflect some clinical trials results on their approval documents. Some examples could be "highly active MS" (HAMS), "active secondary MS" (similar to the old progressive-relapsing) and "rapidly progressing PPMS".

Also, deficits always resolving between attacks is sometimes referred to as "benign" MS, although people still build up some degree of disability in the long term. On the other hand, the term malignant multiple sclerosis is used to describe people with MS having reached significant level of disability in a short period.

An international panel has published a standardized definition for the course HAMS.
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