Moctezuma II
War with Tlaxcala, Huejotzingo and their allies

Though the first conflicts between Mexico and Tlaxcala, Huejotzingo, and their allies began during the rule of Moctezuma I in the 1450s, it was during the reign of Moctezuma II that major conflicts broke through.
detectable_content:number_placeholders[3], combination:two_responses, change_case:english_capital