Anatolia
Early Christian period

After the first division of the Roman Empire, Anatolia became part of the Eastern Roman Empire, otherwise known as the Byzantine Empire or Byzantium. In the 1st century CE, Anatolia became one of the first places where Christianity spread, so that by the 4th century CE, western and central Anatolia were overwhelmingly Christian and Greek-speaking.

Byzantine Anatolia was one of the wealthiest and most densely populated places in the Later Roman Empire. Anatolia's wealth grew during the 4th and 5th centuries thanks, in part, to the Pilgrim's Road that ran through the peninsula. Literary evidence about the rural landscape stems from the Christian hagiographies of the 6th-century Nicholas of Sion and 7th-century Theodore of Sykeon. Large and prosperous urban centers of Byzantine Anatolia included Assos, Ephesus, Miletus, Nicaea, Pergamum, Priene, Sardis, and Aphrodisias.

From the mid-5th century onwards, urbanism was affected negatively and began to decline, while the rural areas reached unprecedented levels of prosperity in the region. Historians and scholars continue to debate the cause of the urban decline in Byzantine Anatolia between the 6th and 7th centuries, variously attributing it to the Plague of Justinian (541), the Byzantine–Sasanian War (602–628), and the Arab invasion of the Levant (634–638).
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