Wuhan
Republic of China

With the northern extension of the Northern Expedition, the center of the Great Revolution shifted from the Pearl River basin to the Yangtze River basin. On November 26, the Kuomintang Central Political Committee decided to move the capital from Guangzhou to Wuhan. In mid-December, most of the KMT central executive commissioners and national government commissioners arrived in Wuhan, set up the temporary joint conference of central executive commissioners and National Government commissioners, performed the top functions of central party headquarters and National Government, declared they would work in Wuhan on January 1, 1927, and decided to combine the towns of Wuchang, Hankou, and Hanyang into Wuhan City, called "Capital District". The new national government, later known as " Wuhan nationalist government ", was based in the Nanyang Building in Hankou, while the central party headquarters and other organizations chose their locations in Hankou or Wuchang.

In March 1927, Mao Zedong appeared at the Third Plenum of the KMT Central Executive Committee in Wuhan, which sought to strip General Chiang of his power by appointing Wang Jingwei leader. The first phase of the Northern Expedition was interrupted by the political split in the Kuomintang following the formation of the Nanjing faction in April 1927 against the existing faction in Wuhan. Members of the Chinese Communist Party, who had survived the April 12 massacre, met at Wuhan and reelected Chen Duxiu (Ch'en Tu-hsiu) as the Party's Secretary General. The split was partially motivated by the purge of the Communists within the party, which marked the end of the First United Front, and Chiang Kai-shek briefly stepped down as the commander of the National Revolutionary Army.

In June 1927, Stalin sent a telegram to the Communists in Wuhan, calling for the mobilization of an army of workers and peasants. This alarmed Wang Jingwei, who decided to break with the Communists and come to terms with Chiang Kai-shek. The Wuhan coup was a political shift made on July 15, 1927, by Wang Jingwei towards Chiang Kai-shek, and his Shanghai -based rival in the Kuomintang. The Wuhan Nationalist Government was established in Wuhan on February 21, 1927, and ended by August 19, 1927. After the end of the Northern Expedition, Hankou was elevated to a centrally-controlled municipality.

In the 1931 China floods, one of the deadliest flood disasters in world history, Wuhan was a refuge for flood victims from outlying areas, who had been arriving since the late spring. But when the city itself was inundated in the early summer, and after a catastrophic dike failure just before 6:00 AM on July 27, an estimated 782,189 urban citizens and rural refugees were left homeless. The flood covered an area of 32 square miles and the city was flooded under many feet of water for close to three months. Large numbers gathered on flood islands throughout the city, with 30,000 sheltering on a railway embankment in central Hankou. With little food and a complete breakdown in sanitation, thousands soon began to succumb to diseases. Jin Shilong, Senior Engineer at the Hubei Flood Prevention Agency, described the flooding:

There was no warning, only a sudden great wall of water. Most of Wuhan's buildings in those days were only one story high, and for many people there was no escape – they died by the tens of thousands.... I was just coming off duty at the company's main office, a fairly new three-story building near the center of town... When I heard the terrible noise and saw the wall of water coming, I raced to the top story of the building.... I was in one of the tallest and strongest buildings left standing. At that time no one knew whether the water would subside or rise even higher.

The high-water mark was reached on August 19 at Hankou, with the water level exceeding 16 m (53 ft) above normal. In 1936, when natural disaster struck Central China with widespread flooding affecting Hebei, Hunan, Jiangxi, Wuhan and Chongqing caused by the Yangtze and Huai Rivers bursting their banks, Ong Seok Kim, as Chairman of the Sitiawan Fundraising and Disaster Relief Committee, raised money and materials in support of the victims.

During the Second Sino-Japanese War and following the fall of Nanking in December 1937, Wuhan had become the provisional capital of China's Kuomintang government, and became another focal point of pitched air battles beginning in early 1938 between modern monoplane bomber and fighter aircraft of the Imperial Japanese forces and the Chinese Air Force, which included support from the Soviet Volunteer Group in both planes and personnel, as U.S. support in war materials waned. As the battle raged on through 1938, Wuhan and the surrounding region had become the site of the Battle of Wuhan. After being taken by the Japanese in late 1938, Wuhan became a major Japanese logistics center for operations in southern China.

In early October 1938, Japanese troops moved east and north in the outskirts of Wuhan. As a result, numerous companies and enterprises and large numbers of people had to withdraw from Wuhan to the west of Hubei and Sichuan. The KMT navy undertook the responsibility of defending the Yangtze River on patrol and covering the withdrawal. On October 24, while overseeing the waters of the Yangtze River near the town of Jinkou (Jiangxia District in Wuhan) in Wuchang, the KMT gunboat Zhongshan came up against six Japanese aircraft. Though two were eventually shot down, the Zhongshan sank with 25 casualties. Raised from the bottom of the Yangtze River in 1997, and restored at a local shipyard, the Zhongshan has been moved to a purpose-built museum in Wuhan's suburban Jiangxia District, which opened on September 26, 2011.

As a key center on the Yangtze, Wuhan was an important base for Japanese operations in China. On December 18, 1944, in a planned strategic move, and as revenge for the torture and execution of three captured American pilots by Japanese soldiers in the city, Wuhan was bombed by 77 American bombers with the approval of Chiang Kai-Shek. This set off a firestorm that destroyed much of the military resources of the city. For the next three days, Wuhan was bombed by the Americans, destroying all of the docks and warehouses of Wuhan, as well as the Japanese air bases in the city. The air raids also killed thousands of Chinese civilians. "According to casualty statistics compiled by Hankou city in 1946, more than 20,000 were killed or injured in the December bombings of 1944."

Wuhan returned to Chinese control in September 1945. Administratively, Wuchang and Hanyang were initially combined into a new City of Wuchang, but in October 1946 were separated into the City of Wuchang (including Wuchang only) and the County of Hanyang. Hankou became a centrally controlled municipality in August 1947. Militarily, the Wuhan Forward Headquarters was established in Wuhan, headed by Bai Chongxi.

During the later stages of the Chinese Civil War, Bai sought to broker peace, proposing that the Communist Party could rule northern China while the Nationalist government retained southern China. This was rejected, and on May 15, 1949, Bai and the Wuhan garrison retreated from the city. People's Liberation Army troops entered Wuhan on the afternoon of Monday, May 16, 1949.
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