Philosophiæ Naturalis Principia Mathematica
Rules of Reason

Perhaps to reduce the risk of public misunderstanding, Newton included at the beginning of Book 3 (in the second (1713) and third (1726) editions) a section titled "Rules of Reasoning in Philosophy". In the four rules, as they came finally to stand in the 1726 edition, Newton effectively offers a methodology for handling unknown phenomena in nature and reaching towards explanations for them. The four Rules of the 1726 edition run as follows (omitting some explanatory comments that follow each):

This section of Rules for philosophy is followed by a listing of "Phenomena", in which are listed a number of mainly astronomical observations, that Newton used as the basis for inferences later on, as if adopting a consensus set of facts from the astronomers of his time.

Both the "Rules" and the "Phenomena" evolved from one edition of the Principia to the next. Rule 4 made its appearance in the third (1726) edition; Rules 1–3 were present as "Rules" in the second (1713) edition, and predecessors of them were also present in the first edition of 1687, but there they had a different heading: they were not given as "Rules", but rather in the first (1687) edition the predecessors of the three later "Rules", and of most of the later "Phenomena", were all lumped together under a single heading "Hypotheses" (in which the third item was the predecessor of a heavy revision that gave the later Rule 3).

From this textual evolution, it appears that Newton wanted by the later headings "Rules" and "Phenomena" to clarify for his readers his view of the roles to be played by these various statements.

In the third (1726) edition of the Principia, Newton explains each rule in an alternative way and/or gives an example to back up what the rule is claiming. The first rule is explained as a philosophers' principle of economy. The second rule states that if one cause is assigned to a natural effect, then the same cause so far as possible must be assigned to natural effects of the same kind: for example, respiration in humans and in animals, fires in the home and in the Sun, or the reflection of light whether it occurs terrestrially or from the planets. An extensive explanation is given of the third rule, concerning the qualities of bodies, and Newton discusses here the generalisation of observational results, with a caution against making up fancies contrary to experiments, and use of the rules to illustrate the observation of gravity and space.
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