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Sports

Professional sports leagues such as the National Football League (NFL), Major League Baseball (MLB), National Basketball Association (NBA), Women's National Basketball Association (WNBA), National Hockey League (NHL), Major League Soccer (MLS), and National Women's Soccer League (NWSL), have team franchises in following Midwestern cities:

Popular teams include the St. Louis Cardinals (11 World Series titles), Cincinnati Reds (5 World Series titles), Chicago Bulls (6 NBA titles), the Detroit Pistons (3 NBA titles), Milwaukee Bucks (2 NBA titles), the Minnesota Lynx (4 WNBA titles), the Green Bay Packers (4 Super Bowl titles, 13 total NFL championships), the Chicago Bears (1 Super Bowl title, 9 total NFL championships), the Cleveland Browns (4 AAFC championships, 4 NFL championships), the Kansas City Chiefs (3 Super Bowl titles, 4 total NFL championships), Kansas City Royals (2 World Series titles), the Detroit Red Wings (11 Stanley Cup titles), the Detroit Tigers (4 World Series titles), the Chicago Blackhawks (6 Stanley Cup titles), and the Columbus Crew (3 MLS Cups).

In NCAA college sports, the Big Ten Conference and the Big 12 Conference feature the largest concentration of top Midwestern Division I football and men's and women's basketball teams in the region, including the Cincinnati Bearcats, Illinois Fighting Illini, Indiana Hoosiers, Iowa Hawkeyes, Iowa State Cyclones, Kansas Jayhawks, Kansas State Wildcats, Michigan Wolverines, Michigan State Spartans, Minnesota Golden Gophers, Nebraska Cornhuskers, Northwestern Wildcats, Ohio State Buckeyes, Purdue Boilermakers, and the Wisconsin Badgers.

Other notable Midwestern college sports teams include the Akron Zips, Ball State Cardinals, Butler Bulldogs, Creighton Bluejays, Dayton Flyers, Grand Valley State Lakers, Indiana State Sycamores, Kent State Golden Flashes, Marquette Golden Eagles, Miami RedHawks, Milwaukee Panthers, Missouri Tigers, Missouri State Bears, Northern Illinois Huskies, North Dakota State Bison, Notre Dame Fighting Irish, Ohio Bobcats, South Dakota State Jackrabbits, Toledo Rockets, Western Michigan Broncos, Wichita State Shockers, and Xavier Musketeers. Of this second group of schools, Butler, Dayton, Indiana State, Missouri State, North Dakota State, and South Dakota State do not play top-level college football (all playing in the second-tier Division I FCS), and Creighton, Marquette, Milwaukee, Wichita State and Xavier do not sponsor football at all.

The Milwaukee Mile hosted its first automobile race in 1903, and is one of the oldest tracks in the world, though as of 2019 is presently inactive. The Indianapolis Motor Speedway, opened in 1909, is a prestigious auto racing track which annually hosts the internationally famous Indianapolis 500-Mile Race (part of the IndyCar series), the Brickyard 400 (NASCAR), and the IndyCar Grand Prix (IndyCar series). The Road America and Mid-Ohio road courses opened in the 1950s and 1960s respectively. Other motorsport venues in the Midwest are Indianapolis Raceway Park (home of the NHRA U.S. Nationals), Michigan International Speedway, Chicagoland Speedway, Kansas Speedway, Gateway International Raceway, and the Iowa Speedway. The Kentucky Speedway is just outside the officially defined Midwest, but is linked with the region because the track is located in the Cincinnati metropolitan area.

Notable professional golf tournaments in the Midwest include the Memorial Tournament, BMW Championship and John Deere Classic.