structural:expansion, stylistic:tone
Abusive requests for Interpol arrests

Despite its politically neutral stance, some have criticized the agency for its role in arrests that critics contend were politically motivated. In their declaration, adopted in Oslo (2010), Monaco (2012), Istanbul (2013), and Baku (2014), the OSCE Parliamentary Assembly (PACE) criticized some OSCE member States for their abuse of mechanisms of the international investigation and urged them to support the reform of Interpol in order to avoid politically motivated prosecution. The resolution of the Parliamentary Assembly of the Council of Europe of 31 January 2014 criticizes the mechanisms of operation of the Commission for the Control of Interpol's files, in particular, non-adversarial procedures and unjust decisions. In 2014, PACE adopted a decision to thoroughly analyse the problem of the abuse of Interpol and to compile a special report on this matter. In May 2015, within the framework of the preparation of the report, the PACE Committee on Legal Affairs and Human Rights organized a hearing in Yerevan, during which both representatives of NGOs and Interpol had the opportunity to speak. According to Freedom House, Russia is responsible for 38% of Interpol's public Red Notices. There currently are "approximately 66,370 valid Red Notices, of which some 7,669 are public."

Refugees who are included in the list of Interpol can be arrested when crossing the border. In the year 2008, the office of the United Nations High Commissioner for Refugees pointed to the problem of arrests of refugees on the request of INTERPOL in connection with politically motivated charges.

In 2021, Turkey, China, the United Arab Emirates, Iran, Russia, and Venezuela were accused of abusing Interpol by using it to target political opponents. China used Interpol against the Uyghurs, where the government issued a Red Notice against activists and other members of the ethnic minority group living abroad. Since 1997, 1,546 cases from 28 countries of detention and deportation of the Uyghurs were recorded. In the case of Turkey, Interpol had to turn down 800 requests, including one for NBA basketball player Enes Kanter Freedom. The UAE was also accused as one of the countries attempting to buy influence in Interpol. Using the Interpol Foundation for a Safer World, the Arab nation gave donations of $54 million. The amount was estimated as equal to the statutory contributions together made by the rest 194 members. It was asserted that the Emirates' growing influence over Interpol gave it the opportunity to host the General Assembly in 2018 and in 2020 (that was postponed due to the COVID-19 pandemic).