stylistic:style_transfer, structural:summarization, information:highlighting
Rise to power

The Ba'ath Party was originally represented in Qasim's cabinet; however, Qasim—reluctant to join Nasser's newly formed union between Egypt and Syria —sided with various groups within Iraq (notably the social democrats and the Iraqi Communist Party) that told him such an action would be dangerous. Instead, Qasim adopted a wataniyah policy of "Iraq First". To strengthen his own position within the government, Qasim also had an alliance with the Iraqi Communist Party, which was opposed to the notion of pan-Arabism. His policies angered several pan-Arab organisations, including the Ba'ath Party, which later began plotting to assassinate Qasim at Al-Rashid Street on 7 October 1959 and take power. Saddam was recruited to the assassination conspiracy by its ring-leader, Abdul Karim al-Shaikhly, after one of the would-be assassins left. During the ambush, Saddam (who was only supposed to provide cover) began shooting prematurely, which disorganised the whole operation. Qasim's chauffeur was killed and Qasim was hit in the arm and shoulder. The assassins thought they had killed Qasim and quickly retreated to their headquarters, but Qasim survived. Saddam himself is not believed to have received any training outside of Iraq, as he was a late addition to the assassination team.

Richard Sale of United Press International (UPI), citing former U.S. diplomat and intelligence officials, Adel Darwish, and other experts, reported that the unsuccessful assassination attempt on Qasim was a collaboration between the United States Central Intelligence Agency (CIA) and Egyptian intelligence. Pertinent contemporary records relating to CIA operations in Iraq have remained classified or heavily redacted, thus "allow for plausible deniability." It is generally accepted that Egypt, in some capacity, was involved in the assassination attempt, and that "he United States was working with Nasser on some level." Sale and Darwish's account has been disputed by historian Bryan R. Gibson who concludes that available U.S. declassified documents show that "while the United States was aware of several plots against Qasim, it had still adhered to nonintervention policy." On the other hand, historian Kenneth Osgood writes that "the circumstantial evidence is such that the possibility of US–UAR collaboration with Ba'ath Party activists cannot be ruled out," concluding that "hatever the validity of charges, at the very least currently declassified documents reveal that US officials were actively considering various plots against Qasim and that the CIA was building up assets for covert operations in Iraq."

At the time of the attack, the Ba'ath Party had fewer than 1,000 members, however the failed assassination attempt led to widespread exposure for Saddam and the Ba'ath within Iraq, where both had previously languished in obscurity, and later became a crucial part of Saddam's public image during his tenure as president of Iraq. Kanan Makiya recounts:

The man and the myth merge in this episode. His biography—and Iraqi television, which stages the story ad nauseam—tells of his familiarity with guns from the age of ten; his fearlessness and loyalty to the party during the 1959 operation; his bravery in saving his comrades by commandeering a car at gunpoint; the bullet that was gouged out of his flesh under his direction in hiding; the iron discipline that led him to draw a gun on weaker comrades who would have dropped off a seriously wounded member of the hit team at a hospital; the calculating shrewdness that helped him save himself minutes before the police broke in leaving his wounded comrades behind; and finally the long trek of a wounded man from house to house, city to town, across the desert to refuge in Syria.

Michel Aflaq, the leader of the Ba'athist movement, organized the expulsion of leading Iraqi Ba'athist members, such as Fuad al-Rikabi, on the grounds that the party should not have initiated the attempt on Qasim's life. At the same time, Aflaq secured seats in the Iraqi Ba'ath leadership for his supporters, one of them being Saddam. The assassins, including Saddam, all eventually escaped to Cairo, Egypt "where they enjoyed Nasser's protection for the remainder of Qasim's tenure in power." Saddam initially escaped to Syria and then to Egypt itself in February 1960, and he continued to live there until 1963, graduating from high school in 1961 and unsuccessfully pursuing a law degree at Cairo Law School (1962–1963). It is possible that Saddam visited the U.S. embassy in Cairo during his exile, and some evidence suggests that he was "in frequent contact with US officials and intelligence agents." A former high-ranking U.S. official told historians Marion Farouk–Sluglett and Peter Sluglett that Iraqi Ba'athists, including Saddam, "had made contact with the American authorities in the late 1950s and early 1960s."

Army officers with ties to the Ba'ath Party overthrew Qasim in the Ramadan Revolution coup of February 1963; long suspected to be supported by the CIA, however pertinent contemporary documents relating to the CIA's operations in Iraq have remained classified by the U.S. government, although the Ba'athists are documented to have maintained supportive relationships with U.S. officials before, during, and after the coup. Ba'athist leaders were appointed to the cabinet and Abdul Salam Arif became president. Arif dismissed and arrested the Ba'athist leaders later that year in the November 1963 Iraqi coup d'état. Being exiled in Egypt at the time, Saddam played no role in the 1963 coup or the brutal anti-communist purge that followed; although he returned to Iraq after the coup, becoming a key organizer within the Ba'ath Party's civilian wing upon his return. Unlike during the Qasim years, Saddam remained in Iraq following Arif's anti-Ba'athist purge in November 1963, and became involved in planning to assassinate Arif. In marked contrast to Qasim, Saddam knew that he faced no death penalty from Arif's government and knowingly accepted the risk of being arrested rather than fleeing to Syria again. Saddam was arrested in October 1964 and served approximately two years in prison before escaping in 1966. In 1966, Ahmed Hassan al-Bakr appointed him Deputy Secretary of the Regional Command. Saddam, who would prove to be a skilled organizer, revitalized the party. He was elected to the Regional Command, as the story goes, with help from Michel Aflaq—the founder of Ba'athist thought. In September 1966, Saddam initiated an extraordinary challenge to Syrian domination of the Ba'ath Party in response to the Marxist takeover of the Syrian Ba'ath earlier that year, resulting in the Party's formalized split into two separate factions. Saddam then created a Ba'athist security service, which he alone controlled.