linguistic:voice_change, quality:corruption
21st century

In 2006, Yale and Peking University (PKU) established a Joint Undergraduate Program in Beijing, an exchange program allowing Yale students to spend a semester living and studying with PKU honor students. In July 2012, the Yale University-PKU Program ended due to weak participation.

In 2007 outgoing Yale President Rick Levin characterized Yale's institutional priorities: "First, among the nation's finest research universities, Yale is distinctively committed to excellence in undergraduate education. Second, in our graduate and professional schools, as well as in Yale College, we are committed to the education of leaders."

In 2009, former British Prime Minister Tony Blair picked Yale as one location – the others being Britain's Durham University and Universiti Teknologi Mara – for the Tony Blair Faith Foundation 's United States Faith and Globalization Initiative. As of 2009, former Mexican President Ernesto Zedillo is the director of the Yale Center for the Study of Globalization and teaches an undergraduate seminar, "Debating Globalization". As of 2009, former presidential candidate and DNC chair Howard Dean teaches a residential college seminar, "Understanding Politics and Politicians". Also in 2009, an alliance was formed among Yale, University College London, and both schools' affiliated hospital complexes to conduct research focused on the direct improvement of patient care—a field known as translational medicine. President Richard Levin noted that Yale has hundreds of other partnerships across the world, but "no existing collaboration matches the scale of the new partnership with UCL". In August 2013, a new partnership with the National University of Singapore led to the opening of Yale-NUS College in Singapore, a joint effort to create a new liberal arts college in Asia featuring a curriculum including Western and Asian traditions.

In 2017, having been suggested for decades, Yale University renamed Calhoun College, named for slave owner, anti-abolitionist, and white supremacist Vice President John C. Calhoun. It is now Hopper College, after Grace Hopper.

In 2020, in the wake of the George Floyd protests, the #CancelYale tag was used on social media to demand that Elihu Yale's name be removed from Yale University. Much of the support originated from right-wing pundits such as Mike Cernovich and Ann Coulter, who intended to satirize what they perceived as the excesses of cancel culture. Yale spent most of his professional career in the employ of the East India Company (EIC), serving as the governor of the Presidency of Fort St. George in modern-day Chennai. The EIC, including Yale himself, was involved in the Indian Ocean slave trade, though the extent of Yale's involvement in slavery remains debated. His singularly large donation led critics to argue Yale University relied on money derived from slavery for its first scholarships and endowments.

In 2020, the US Justice Department sued Yale for alleged discrimination against Asian and white candidates, through affirmative action admission policies. In 2021, under the new Biden administration, the Justice Department withdrew the lawsuit. The group, Students for Fair Admissions, later won a similar lawsuit against Harvard.