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Toxicity

Like other plant species in the family Moraceae, contact with the milky sap of Ficus carica followed by exposure to ultraviolet light can cause phytophotodermatitis, a potentially serious skin inflammation. Although the plant is not poisonous per se, F. carica is listed in the FDA Database of Poisonous Plants.

Organic chemical compounds called furanocoumarins are known to cause phytophotodermatitis in humans. The common fig contains significant quantities of two furanocoumarins, psoralen and bergapten. The essential oil of fig leaves contains more than 10% psoralen, the highest concentration of any organic compound isolated from fig leaves. Psoralen appears to be the primary furanocoumarin compound responsible for fig leaf-induced phytophotodermatitis.

Psoralen and bergapten are found chiefly in the milky sap of the leaves and shoots of F. carica but not the fruits. Neither psoralen nor bergapten were detected in the essential oil of fig fruits. Thus there is no conclusive evidence that fig fruits cause phytophotodermatitis.