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Thallium stress test

A thallium stress test is a form of scintigraphy in which the amount of thallium in tissues correlates with tissue blood supply. Viable cardiac cells have normal Na /K ion-exchange pumps. The Tl cation binds the K pumps and is transported into the cells. Exercise or dipyridamole induces widening (vasodilation) of arteries in the body. This produces coronary steal by areas where arteries are maximally dilated. Areas of infarct or ischemic tissue will remain "cold". Pre- and post-stress thallium may indicate areas that will benefit from myocardial revascularization. Redistribution indicates the existence of coronary steal and the presence of ischemic coronary artery disease.