structural:reformatting, information:classification, structural:expansion, quality:correction
Intra-mutant spectrum interactions for interference, complementation or cooperation

Opposite to suppression is maintenance of a mutant either by a favorable position in a fitness landscape or by interactions of complementation or cooperation with members of the mutant spectrum. The position in a fitness landscape influences vulnerability to mutations, as popularized with the terms "advantage of the flattest" or "survival of the flattest", indicating that a variant located at the top of a sharp fitness peak has higher probability to decrease fitness as a result of new mutations than the same variant located at a fitness plateau. Survival of the flattest has been also proposed as an ingredient in some models of the error threshold.