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House is an American medical drama television series that originally ran on the Fox network for eight seasons, from November 16, 2004, to May 21, 2012. Its main character, Dr. Gregory House, is an unconventional, misanthropic, cynical medical genius who, despite his dependence on pain medication, successfully leads a team of diagnosticians at the fictional Princeton–Plainsboro Teaching Hospital (PPTH) in New Jersey. The series' premise originated with Paul Attanasio, while David Shore, who is credited as creator, was primarily responsible for conceiving the title character. House often clashes with his fellow physicians, including his own diagnostic team, because many of his hypotheses about patients' illnesses are based on subtle or controversial insights. His flouting of hospital rules and procedures frequently leads him into conflict with his boss, hospital administrator and Dean of Medicine Dr. Lisa Cuddy. His only true friend is Dr. James Wilson, head of the Department of Oncology. During the first three seasons, House's diagnostic team consists of Dr. Robert Chase, Dr. Allison Cameron and Dr. Eric Foreman. At the end of the third season, this team disbands. Rejoined by Foreman, House gradually selects three new team members: Dr. Remy "Thirteen" Hadley, Dr. Chris Taub and Dr. Lawrence Kutner. Chase and Cameron continue to appear occasionally in different roles at the hospital. Kutner dies late in season five; early in season six, Cameron departs the hospital, and Chase returns to the diagnostic team. Thirteen takes a leave of absence for most of season seven, and her position is filled by medical student Martha M. Masters. Cuddy and Masters depart before season eight; Foreman becomes the new Dean of Medicine, while Dr. Jessica Adams and Dr. Chi Park join House's team. The series' executive producers included Shore, Attanasio, Attanasio's business partner Katie Jacobs, and film director Bryan Singer. It was filmed largely in a neighborhood and business district in Los Angeles County's Westside called Century City. The series was produced by Attanasio and Jacobs' Heel and Toe Films, Shore's Shore Z Productions, Singer's Bad Hat Harry Productions, and Universal Television. House was among the top 10 series in the United States from its second through fourth seasons. Distributed to 71 countries, it was the most-watched TV program in the world in 2008. It received numerous awards, including five Primetime Emmy Awards, two Golden Globe Awards, a Peabody Award, and nine People's Choice Awards. On February 8, 2012, Fox announced that the eighth season, then in progress, would be its last. The series finale aired on May 21, 2012, following an hour-long retrospective.