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First marriage

In 1838–39, the young bachelor, Alexander made the Grand Tour of Europe which was standard for young men of his class at that time. One of the purposes of the tour was to select a suitable bride for himself. His father Nicholas I of Russia suggested Princess Alexandrine of Baden as a suitable choice, but he was prepared to allow Alexander to choose his own bride, as long as she was not Roman Catholic or a commoner. Alexander stayed for three days with the maiden Queen Victoria. The two got along well, but there was no question of marriage between two major monarchs.

In Germany, Alexander made an unplanned stop in Darmstadt. He was reluctant to spend "a possibly dull evening" with their host Louis II, Grand Duke of Hesse and by Rhine, but he agreed to do so because Vasily Zhukovsky insisted that his entourage was exhausted and needed a rest. During dinner, he met and was charmed by Princess Marie, the 14-year-old daughter of Louis II. He was so smitten that he declared that he would rather abandon the succession than not marry her. He wrote to his father: "I liked her terribly at first sight. If you permit it, dear father, I will come back to Darmstadt after England." When he left Darmstadt, she gave him a locket that contained a piece of her hair.

Alexander's parents initially did not support his decision to marry Princess Marie of Hesse. There were troubling rumors about her paternity. Although she was the legal daughter of Louis II, there were rumors that Marie was the biological daughter of her mother's lover, Baron August von Senarclens de Grancy. Alexander's parents worried that Marie could have inherited her mother's consumption. Alexander's mother considered the Hesse family grossly inferior to the Hohenzollerns and Romanovs.

In April 1840, Alexander's engagement to Princess Marie was officially announced. In August, the 16-year-old Marie left Darmstadt for Russia. In December, she was received into the Orthodox Church and received the names Maria Alexandrovna.

On 16 April 1841, aged 23, Tsesarevitch Alexander married Marie in St. Petersburg.

The marriage produced six sons and two daughters:

Alexander particularly placed hope in his eldest son, Tsesarevich Nicholas. In 1864, Alexander II found Nicholas a bride, Princess Dagmar of Denmark, second daughter of King Christian IX of Denmark and younger sister to Alexandra, Princess of Wales and King George I of Greece. In 1865, Nicholas died of cerebrospinal meningitis. Alexander was devastated by Nicholas' death, and his nephew Grand Duke Alexander Mikhailovich of Russia reflected that "his shoulders were bent, and he walked so slowly that we all felt as though his loss had robbed him of all his strength."

Alexander's second son, Grand Duke Alexander became heir and married his late brother 's fiancée. The couple married in November 1866, with Dagmar converting to Orthodoxy and taking the name Maria Feodorovna.

Alexander grew estranged from his second son, Grand Duke Alexander.

Alexander's favorite child was his daughter, Grand Duchess Marie Alexandrovna. He reflected that his daughter had "never caused us anything but joy. We lost our eldest girl and we had so ardently wished for another – her birth was a joy and a delight, not to be described, and her whole life has been a continuation." In 1873, a quarrel broke out between the courts of Queen Victoria and Alexander II, when Victoria's second son, Prince Alfred, made it known that he wished to marry the Grand Duchess. The tsar objected to the queen's request to have his daughter come to England in order to meet her, and after the January 1874 wedding in St. Petersburg, the tsar insisted that his daughter be granted precedence over the Princess of Wales, which the queen rebuffed. Later that year, after attending the engagement ceremonies of his second surviving son, Vladimir, to Marie of Mecklenburg-Schwerin in Berlin, Alexander II, with his third son, Alexei, accompanying him, made a visit to England. While not a state visit, but simply a trip to see his daughter, he nevertheless partook in receptions at Buckingham Palace and Marlborough House, inspected the artillery at the Royal Arsenal in Woolwich, reviewed troops at Aldershot and met both Prime Minister Benjamin Disraeli and the leader of the opposition, William Gladstone. Disraeli observed of the tsar that "his mien and manners are gracious and graceful, but the expression of his countenance, which I could now very closely examine, is sad. Whether it is satiety, or the loneliness of despotism, or fear of a violent death, I know not, but it was a visage of, I should think, habitual mournfulness."

In 1866, Alexander II took a mistress, Catherine Dolgorukova, with whom he would father three surviving children. In 1880, he moved his mistress and their children into the Winter Palace. Alexander's affair alienated all his children except Alexei and Marie Alexandrovna. Courtiers spread stories that the dying Empress Marie was forced to hear the noise of Catherine's children moving about overhead, but their respective rooms were actually far. In May 1880, Grand Duchess Marie Alexandrovna visited Russia to see her dying mother. She was horrified to learn that Catherine lived in the Palace and she confronted him. Shocked by the loss of support from his daughter, he quietly retreated to Gatchina Palace for military reviews. The quarrel, however, evidently, jolted his conscience enough to lead him to return to St. Petersburg each morning to ask after his wife's health.

Empress Marie Alexandrovna suffered from tuberculosis. She succumbed to it on 3 June 1880.