structural:reformatting, structural:expansion
Achyrocline bogotensis antiviral therapy

In a study by Tellez et al., extracts from a plant Achyrocline bogotensis was used to develop an antiviral therapy for both rotavirus and astrovirus. Achyrocline bogotensis was commonly used for skin and urinary infections. Drug testing methodology involved application of the extract to cell for pre-treatment (blocking), direct viral activity (evidence of killing the virus), and treatment (a decrease in the viral load after an infection is established). The extract demonstrated direct viral activity by killing astroviruses directly and treatment by leading to a decrease in the viral load after an established infection. A pre-treatment effect was not evident during the experiment.