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Marriage and family

Hanks married American actress Samantha Lewes (1952–2002) in 1978. They had one son, actor Colin (b. 1977), and one daughter, Elizabeth (b. 1982). Hanks and Lewes divorced in 1987. Lewes died in 2002 at the age of 49 from bone cancer. Hanks actively attends church. He said, "I must say that when I go to church—and I do go to church—I ponder the mystery. I meditate on the 'why?' of 'why people are as they are' and 'why bad things happen to good people,' and 'why good things happen to bad people' The mystery is what I think is, almost, the grand unifying theory of all mankind."

In 1981, Hanks met actress Rita Wilson on the set of TV comedy Bosom Buddies (1980–1982). They were reunited in 1985 on the set of Volunteers. Wilson is of Greek and Bulgarian descent, and a member of the Greek Orthodox Church. Before marrying her, Hanks converted to her faith. Hanks and Wilson married in 1988 and have two sons. Their older son, Chet, released a rap song in 2011 and had recurring roles in Empire and Shameless. Their younger son, Truman, was born in 1995, and portrayed the younger version of his father's character in A Man Called Otto (2022). Hanks lives with his family in Los Angeles, California, and Ketchum, Idaho.

In October 2013, Hanks said he has type 2 diabetes.

Despite being a fan of the Oakland Athletics and the Raiders when they were based in Oakland, Hanks stated in April 2017 he would boycott the NFL for two years after the Raiders filed for relocation to Las Vegas. Since 1984, Hanks has been an avid fan of the English Premier League club Aston Villa.

In November 2019, shortly before the release of A Beautiful Day in the Neighborhood, a drama film in which Hanks portrays Fred Rogers, he learned through Ancestry.com that he and Rogers were sixth cousins, both descendants of Johannes Meffert (1732–1795), who was born in Schöneck, Hesse, Germany (then part of the Holy Roman Empire) and emigrated to the United States in the 18th century, settling in Kentucky and changing his last name to Mefford. Hanks is also a distant relative of the 16th US president, Abraham Lincoln. Hanks narrated the 2011 television program Killing Lincoln.

On December 27, 2019, the President of Greece, Prokopis Pavlopoulos, signed an honorary naturalization order for Hanks and his family, citing their "exceptional services to Greece", thus making him and his immediate family Greek citizens. Hanks, along with Wilson and their children, were conferred honorary citizenship for their role in bringing global attention and appealing for aid after a devastating wildfire that ripped through the seaside village of Mati, near Athens, in July 2018, which killed more than 100 people. Greece's Interior Minister Takis Theodorikakos said Hanks "showed real interest in the people who suffered from the fire in Mati and promoted this issue in the global media". On July 26, 2020, the Prime Minister of Greece, Kyriakos Mitsotakis, accompanied with his wife, handed over Greek passports to both Hanks and Wilson.