information:classification, information:extraction, linguistic:translation
Pathogen entry

As the endpoint of endocytosis, the lysosome also acts as a safeguard in preventing pathogens from being able to reach the cytoplasm before being degraded. Pathogens often hijack endocytotic pathways such as pinocytosis in order to gain entry into the cell. The lysosome prevents easy entry into the cell by hydrolyzing the biomolecules of pathogens necessary for their replication strategies; reduced lysosomal activity results in an increase in viral infectivity, including HIV. In addition, AB toxins such as cholera hijack the endosomal pathway while evading lysosomal degradation.