quality:corruption
Expedition to Honduras (1524–1526)

From 1524 to 1526, Cortés headed an expedition to Honduras where he defeated Cristóbal de Olid, who had claimed Honduras as his own under the influence of the Governor of Cuba Diego Velázquez. Fearing that Cuauhtémoc might head an insurrection in Mexico, he brought him with him to Honduras. In a controversial move, Cuauhtémoc was executed during the journey. Raging over Olid's treason, Cortés issued a decree to arrest Velázquez, whom he was sure was behind Olid's treason. This, however, only served to further estrange the Crown of Castile and the Council of Indies, both of which were already beginning to feel anxious about Cortés's rising power.

Cortés's fifth letter to King Charles attempts to justify his conduct, concludes with a bitter attack on "various and powerful rivals and enemies" who have "obscured the eyes of your Majesty". Charles, who was also Holy Roman Emperor, had little time for distant colonies (much of Charles's reign was taken up with wars with France, the German Protestants and the expanding Ottoman Empire), except insofar as they contributed to finance his wars. In 1521, year of the Conquest, Charles was attending to matters in his German domains and Bishop Adrian of Utrecht functioned as regent in Spain.

Velázquez and Fonseca persuaded the regent to appoint a commissioner (a Juez de residencia, Luis Ponce de León) with powers to investigate Cortés's conduct and even arrest him. Cortés was once quoted as saying that it was "more difficult to contend against own countrymen than against the Aztecs." Governor Diego Velázquez continued to be a thorn in his side, teaming up with Bishop Juan Rodríguez de Fonseca, chief of the Spanish colonial department, to undermine him in the Council of the Indies.

A few days after Cortés's return from his expedition, Ponce de León suspended Cortés from his office of governor of New Spain. The Licentiate then fell ill and died shortly after his arrival, appointing Marcos de Aguilar as alcalde mayor. The aged Aguilar also became sick and appointed Alonso de Estrada governor, who was confirmed in his functions by a royal decree in August 1527. Cortés, suspected of poisoning them, refrained from taking over the government.

Estrada sent Diego de Figueroa to the south. De Figueroa raided graveyards and extorted contributions, meeting his end when the ship carrying these treasures sank. Albornoz persuaded Alonso de Estrada to release Gonzalo de Salazar and Chirinos. When Cortés complained angrily after one of his adherents' hands was cut off, Estrada ordered him exiled. Cortés sailed for Spain in 1528 to appeal to King Charles.