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Prehistory (before 800 BC)

The oldest human (Neanderthal) traces in the Netherlands, believed to be about 250,000 years old, were found near Maastricht. At the end of the Ice Age, the nomadic late Upper Palaeolithic Hamburg culture (13,000–10,000 BC) hunted reindeer in the area, using spears. The later Ahrensburg culture (11,200–9,500 BC) used bow and arrow. From Mesolithic Maglemosian-like tribes (c. 8000 BC), the world's oldest canoe was found in Drenthe.

Indigenous late Mesolithic hunter-gatherers from the Swifterbant culture (c. 5600 BC), related to the southern Scandinavian Ertebølle culture, were strongly linked to rivers and open water. Between 4800 and 4500 BC, the Swifterbant people started to adopt from the neighbouring Linear Pottery culture the practice of animal husbandry, and between 4300 and 4000 BC agriculture. The Funnelbeaker culture (4300–2800 BC) erected the dolmens, large stone grave monuments found in Drenthe. There was a quick transition from the Funnelbeaker farming culture to the pan-European Corded Ware pastoralist culture (c. 2950 BC). In the southwest, the Seine-Oise-Marne culture —related to the Vlaardingen culture (c. 2600 BC)—survived well into the Neolithic period, until it too was succeeded by the Corded Ware culture.

The subsequent Bell Beaker culture (2700–2100 BC) introduced metalwork in copper, gold and later bronze and opened new international trade routes, reflected in copper artefacts. Finds of rare bronze objects suggest that Drenthe was a trading centre in the Bronze Age (2000–800 BC). The Bell Beaker culture developed locally into the Barbed-Wire Beaker culture (2100–1800 BC) and later the Elp culture (1800–800 BC), a Middle Bronze Age culture marked by earthenware pottery. The southern region became dominated by the related Hilversum culture (1800–800 BC).