structural:scholar_edition, stylistic:tone
Human use

The American bullfrog provides a food source, especially in the Southern and some areas of the Midwestern United States. The traditional way of hunting them is to paddle or pole silently by canoe or flatboat in ponds or swamps at night; when the frog's call is heard, a light is shone at the frog which temporarily inhibits its movement. The frog will not jump into deeper water as long as it is approached slowly and steadily. When close enough, the frog is gigged with a multiple-tined spear and brought into the boat. Bullfrogs can also be stalked on land, by again taking great care not to startle them. In some states, breaking the skin while catching them is illegal, and either grasping gigs or hand captures used. The only parts normally eaten are the rear legs, which resemble small chicken drumsticks, have a similar flavor and texture and can be cooked in similar ways.

Commercial bullfrog culture in near-natural enclosed ponds has been attempted, but is fraught with difficulties. Although pelleted feed is available, the frogs will not willingly consume artificial diets, and providing sufficient live prey is challenging. Disease also tends to be a problem even when great care is taken to provide sanitary conditions. Other challenges to be overcome may be predation, cannibalism, and low water quality. The frogs are large, have powerful leaps, and inevitably escape after which they may wreak havoc among the native frog population. Countries that export bullfrog legs include the Netherlands, Belgium, Mexico, Bangladesh, Japan, China, Taiwan, and Indonesia. Most of these frogs are caught from the wild, but some are captive-reared. The United States is a net importer of frog legs.

The American bullfrog is used as a specimen for dissection in many schools across the world. It is the state amphibian of Missouri, Ohio, and Oklahoma.