stylistic:tone, information:classification
Chemical Revolution

Many of the friends that Priestley made in Birmingham were members of the Lunar Society, a group of manufacturers, inventors, and natural philosophers who assembled monthly to discuss their work. The core of the group included men such as the manufacturer Matthew Boulton, the chemist and geologist James Keir, the inventor and engineer James Watt, and the botanist, chemist, and geologist William Withering. Priestley was asked to join this unique society and contributed much to the work of its members. As a result of this stimulating intellectual environment, he published several important scientific papers, including "Experiments relating to Phlogiston, and the seeming Conversion of Water into Air" (1783). The first part attempts to refute Lavoisier's challenges to his work on oxygen; the second part describes how steam is "converted" into air. After several variations of the experiment, with different substances as fuel and several different collecting apparatuses (which produced different results), he concluded that air could travel through more substances than previously surmised, a conclusion "contrary to all the known principles of hydrostatics". This discovery, along with his earlier work on what would later be recognised as gaseous diffusion, would eventually lead John Dalton and Thomas Graham to formulate the kinetic theory of gases.

In 1777, Antoine Lavoisier had written Mémoire sur la combustion en général, the first of what proved to be a series of attacks on phlogiston theory; it was against these attacks that Priestley responded in 1783. While Priestley accepted parts of Lavoisier's theory, he was unprepared to assent to the major revolutions Lavoisier proposed: the overthrow of phlogiston, a chemistry based conceptually on elements and compounds, and a new chemical nomenclature. Priestley's original experiments on "dephlogisticated air" (oxygen), combustion, and water provided Lavoisier with the data he needed to construct much of his system; yet Priestley never accepted Lavoisier's new theories and continued to defend phlogiston theory for the rest of his life. Lavoisier's system was based largely on the quantitative concept that mass is neither created nor destroyed in chemical reactions (i.e., the conservation of mass). By contrast, Priestley preferred to observe qualitative changes in heat, colour, and particularly volume. His experiments tested "airs" for "their solubility in water, their power of supporting or extinguishing flame, whether they were respirable, how they behaved with acid and alkaline air, and with nitric oxide and inflammable air, and lastly how they were affected by the electric spark."

By 1789, when Lavoisier published his Traité Élémentaire de Chimie and founded the Annales de Chimie, the new chemistry had come into its own. Priestley published several more scientific papers in Birmingham, the majority attempting to refute Lavoisier. Priestley and other Lunar Society members argued that the new French system was too expensive, too difficult to test, and unnecessarily complex. Priestley in particular rejected its "establishment" aura. In the end, Lavoisier's view prevailed: his new chemistry introduced many of the principles on which modern chemistry is founded.

Priestley's refusal to accept Lavoisier's "new chemistry"—such as the conservation of mass—and his determination to adhere to a less satisfactory theory has perplexed many scholars. Schofield explains it thus: "Priestley was never a chemist; in a modern, and even a Lavoisierian, sense, he was never a scientist. He was a natural philosopher, concerned with the economy of nature and obsessed with an idea of unity, in theology and in nature." Historian of science John McEvoy largely agrees, writing that Priestley's view of nature as coextensive with God and thus infinite, which encouraged him to focus on facts over hypotheses and theories, prompted him to reject Lavoisier's system. McEvoy argues that "Priestley's isolated and lonely opposition to the oxygen theory was a measure of his passionate concern for the principles of intellectual freedom, epistemic equality and critical inquiry." Priestley himself claimed in the last volume of Experiments and Observations that his most valuable works were his theological ones because they were "superior dignity and importance".