stylistic:style_transfer, structural:summarization
1950–1959: Established director

In 1951, Wyler produced and directed Kirk Douglas and Eleanor Parker in Detective Story, portraying a day in the lives of the various people in a detective squad. Lee Grant and Joseph Wiseman made their screen debuts in the film, which was nominated for four Academy Awards, including one for Grant. Critic Bosley Crowther lauded the film, describing it as "a brisk, absorbing film by producer-director William Wyler, with the help of a fine, responsive cast."

Carrie was released in 1952 starring Jennifer Jones in the title role and Laurence Olivier as Hurstwood. Eddie Albert played Charles Drouet. Carrie received two Academy Award nominations: Costume Design (Edith Head), and Best Art Direction (Hal Pereira, Roland Anderson, Emile Kuri). Wyler was reluctant to cast Jennifer Jones, and the filming was subsequently plagued by a variety of troubles. Jones had not revealed that she was pregnant; Wyler was mourning the death of his year-old son; Olivier had a painful leg ailment, and he developed a dislike for Jones. Hollywood was reeling under the effects of McCarthyism, and the studio was afraid to distribute a film that could be attacked as immoral. Ultimately, the ending was changed and the film was cut to make it more positive in tone.

During the immediate postwar period, Wyler directed a handful of critically acclaimed and influential films. Roman Holiday (1953) introduced Audrey Hepburn to U.S. audiences in her first starring role, winning her an Academy Award for Best Actress. Wyler said of Hepburn years later, when describing truly great actresses, "In that league there's only ever been Garbo, and the other Hepburn, and maybe Bergman. It's a rare quality, but boy, do you know when you've found it." The film was an instant hit, also winning for Best Costume Design (Edith Head), and Best Writing (Dalton Trumbo). Hepburn would eventually do three movies with Wyler, who her son said was one of the most important directors in her career.

Friendly Persuasion (1956) was awarded the Palme d'Or (Golden Palm) at the Cannes Film Festival. And in 1959, Wyler directed Ben-Hur, which won 11 Oscars, a feat unequaled until Titanic in 1997 and The Lord of the Rings: The Return of the King in 2003. He had also assisted in the production of the 1925 version.

Wyler and its star, Charlton Heston, both knew what the film meant for MGM, which had massive investments in its outcome, with the film's budget having gone from $7 million to $15 million, and the fact that MGM was already in dire financial straits. They were aware that if it failed at the box office, MGM might go bankrupt.

The film, like many epics, was difficult to make. When Heston was asked which scene he enjoyed doing most, he said "I didn't enjoy any of it. It was hard work." Part of the reason for that was the financial stress placed on making the film a success. With a cast of fifteen thousand extras, a leading star, and shot on 70mm film with stereophonic tracks, it was the most expensive film ever made at that time. The nine-minute chariot race, for example, took six months to film.

Ben-Hur became a great box office success. Wyler won his third Academy Award for Best Director and Charlton Heston his first and only Academy Award as its star. Heston recalled in his autobiography that at first he had doubts about playing the role. But his agent advised him otherwise: "Don't you know that actors take parts with Wyler without even reading the damn script? I'm telling you, you have to do this picture!"

Kirk Douglas had lobbied Wyler, who directed him in Detective Story in 1951, for the title role, but only after Wyler had already decided on Heston. He offered him instead the role of Messala, which Douglas rejected. Douglas then went on to star in Spartacus (1960).

Ben-Hur cost $15 million to produce but earned $47 million by the end of 1961 and $90 million worldwide. Audiences mobbed movie theaters in the months after it opened. Critic Pauline Kael praised Wyler's achievement:

I admire the artist who can make something good for the art house audience; but I also applaud the commercial heroism of a director who can steer a huge production and keep his sanity and perspective and decent human feelings beautifully intact.