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Disruption of the menstrual cycle and hormone production

High levels of physical or emotional stress or exposure to chemicals such as pesticides, polychlorinated biphenyls (PCBs), organic solvents and carbon disulfide, may disrupt the balance between the brain, pituitary gland, and ovaries. This disruption can result in an imbalance of estrogen and progesterone, and lead to changes in menstrual cycle length and regularity and ovulation. Because these sex hormones have effects throughout a woman's body, severe or long-lasting hormone imbalances may affect a woman's overall health.

Hazards that can disrupt the menstrual cycle and/or sex hormone production include: