stylistic:tone
Cause

Prostate cancer is caused by the accumulation of genetic mutations to the DNA of cells in the prostate. These mutations affect genes involved in cell growth, replication, cell death, and DNA damage repair. With these processes dysregulated, some cells replicate abnormally, forming a clump of cells called a tumor. As the tumor grows, its cells accumulate more mutations, allowing it to stimulate the growth of new blood vessels to support further growth. Eventually, a tumor can grow large enough to invade nearby organs such as the seminal vesicles or bladder. In advanced tumors, cells can develop the ability to detach from their original tissue site, and evade the immune system. These cells can spread through the lymphatic system to nearby lymph nodes, or through the bloodstream to the bone marrow and (more rarely) other body sites. At these new sites, the cancer cells disrupt normal body function and continue to grow. Metastases cause most of the discomfort associated with prostate cancer, and can eventually kill the affected person.