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Situation during geologic time scales

The icing of Antarctica began in the Late Palaeocene or middle Eocene between 60 and 45.5 million years ago and escalated during the Eocene–Oligocene extinction event about 34 million years ago. CO levels were then about 760 ppm and had been decreasing from earlier levels in the thousands of ppm. Carbon dioxide decrease, with a tipping point of 600 ppm, was the primary agent forcing Antarctic glaciation. The glaciation was favored by an interval when the Earth's orbit favored cool summers but oxygen isotope ratio cycle marker changes were too large to be explained by Antarctic ice-sheet growth alone indicating an ice age of some size. The opening of the Drake Passage may have played a role as well though models of the changes suggest declining CO levels to have been more important.

The Western Antarctic ice sheet declined somewhat during the warm early Pliocene epoch, approximately five to three million years ago; during this time the Ross Sea opened up. But there was no significant decline in the land-based Eastern Antarctic ice sheet.