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Other rivalries

Nadal and Juan Martin del Potro met 17 times, with Nadal leading 11–6. Outside the Big Four, no active player has more wins against Nadal than del Potro. The two met in many prestigious tournaments, including at three of the four majors and the Olympics. Nadal won their first four meetings between 2007 and 2009, before del Potro went on to win the next three, including a straight-sets victory at the 2009 US Open semifinals. Their next significant meeting came during the 2011 Davis Cup final. Nadal beat del Potro in four sets to claim the Davis Cup for Spain. In 2013, Nadal denied del Potro his first Masters title, with a victory in the final of the Indian Wells Open. However, del Potro sought revenge in the semifinals of the 2016 Rio Olympics, narrowly beating Nadal via a third-set tiebreak. They then played a further four matches, all of which in majors, first at the 2017 US Open, which Nadal won in four sets, and then they met in three of the four majors in 2018, including a memorable match in the Wimbledon quarterfinals that lasted nearly five hours, with Nadal winning. The pair met for the last time at the 2018 US Open, where Nadal retired against del Potro in the semifinals.

Nadal and Tomáš Berdych met a total of 24 times, with Nadal leading 20–4. Although this rivalry is lopsided in favor of Nadal, the two had several close matches in prestigious tournaments. Their first match was a final in Båstad, which Nadal won. They then met four times in 2005–06, all in Masters tournaments, with Berdych winning in three. Their biggest meeting came in the 2010 Wimbledon final, which Nadal won in straight sets. Their next most significant meeting was in the opening round of the 2009 Davis Cup Final, where Nadal again defeated Berdych in straight sets en route to the title. At the 2015 Australian Open quarterfinal, following 18 straight losses over 9 years, Berdych was able to claim his only win over Nadal in a Grand Slam, winning in straight sets, including a "bagel" (6–0) in the second.

Nadal and compatriot David Ferrer met a total of 32 times, with Nadal leading 26–6. They have faced each other in finals on eight occasions, including two pairs of consecutive finals in Barcelona (2008–09 and 2011–12), with Nadal winning all of them. Their biggest meeting came in the 2013 French Open final, which Nadal won in straight sets.