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Consumption levels

The United States Food and Drug Administration regards that foods containing liquorice and its derivatives (including glycyrrhizin) are generally recognized as safe for use as a food ingredient, if not consumed excessively. Other jurisdictions have suggested no more than 100–200 mg (1.5–3.1 grains) of glycyrrhizin per day, the equivalent of about 70–150 g (2 + 1 ⁄ 2 – 5 + 1 ⁄ 4 oz) of liquorice confectionery. Although liquorice is considered safe as a food ingredient, glycyrrhizin can cause serious side effects if consumed in large amounts (above 0.2 mg per kg per day). One estimate is that a normal healthy person can consume 10 mg (0.15 grains) of glycyrrhizic acid per day.

Because the composition of liquorice extracts in various products may exist in a broad range, there is not enough scientific information to determine that a specific level of intake is safe or unsafe.