structural:expansion, quality:corruption
Post-Microsoft

Since leaving day-to-day operations at Microsoft, Gates has continued his philanthropy and works on other projects. He stepped down as chairman of Microsoft in February 2014 to become technology advisor at the firm to support newly appointed CEO Satya Nadella.

Gates provided his perspective on a range of issues in an interview that was published in the March 2014 issue of Rolling Stone magazine. In the interview, he provided his perspective on climate change, his charitable activities, various tech companies and people involved in them, and the state of America. In response to a question about his greatest fear when he looks 50 years into the future, Gates stated: "there'll be some really bad things that'll happen in the next 50 or 100 years, but hopefully none of them on the scale of, say, a million people that you didn't expect to die from a pandemic, or nuclear or bioterrorism." Gates also identified innovation as the "real driver of progress" and pronounced that "America's way better today than it's ever been." Gates has often expressed concern about the potential harms of superintelligence; in a Reddit "ask me anything", he stated that:

First the machines will do a lot of jobs for us and not be super intelligent. That should be positive if we manage it well. A few decades after that though the intelligence is strong enough to be a concern. I agree with Elon Musk and some others on this and don't understand why some people are not concerned.

In an interview that was held at the TED conference in March 2015, with Baidu co-founder and CEO, Robin Li, Gates said he would "highly recommend" Nick Bostrom 's recent work, Superintelligence: Paths, Dangers, Strategies. During the conference, Gates warned that the world was not prepared for the next pandemic, a situation that would come to pass in late 2019 when the COVID-19 pandemic began. In March 2018, Gates met at his home in Seattle with Mohammed bin Salman, the crown prince and de facto ruler of Saudi Arabia to discuss investment opportunities for Saudi Vision 2030. In June 2019, Gates admitted that losing the mobile operating system race to Android was his biggest mistake. He stated that it was within their skill set of being the dominant player, but partially blames the antitrust litigation during the time. That same year, Gates became an advisory board member of the Bloomberg New Economy Forum.

In March 2020, Microsoft announced Gates would be leaving his board positions at Berkshire Hathaway and Microsoft to dedicate himself to philanthropic endeavors such as climate change, global health and development, and education. The Wall Street Journal reported in May 2021 that Gates stepped down before Microsoft's board finished its investigation into Gates's alleged inappropriate sexual relationship with a Microsoft employee, which an external law firm had begun probing in late 2019.

During the COVID-19 pandemic, Gates has widely been looked at by media outlets as an expert on the issue, despite him not being a public official or having any prior medical training. His foundation did, however, establish the COVID-19 Therapeutics Accelerator in 2020 to hasten the development and evaluation of new and repurposed drugs and biologics to treat patients for COVID-19, and, as of February 2021, Gates expressed that he and Anthony Fauci frequently talk and collaborate on matters including vaccines and other medical innovations to fight the pandemic.