structural:scholar_edition, stylistic:tone
Stress-related

When the body is stressed, the sympathetic adrenal-medullary (SAM) axis is activated, followed by the hypothalamic-pituitary-adrenal (HPA) axis. These events suppress the HPO axis because the corticotropin-releasing hormone (CRH) released by the HPA axis inhibit the secretion of GnRH by the hypothalamus. CRH also stimulates secretion of beta(β)-endorphins, which suppresses release of GnRH and dopamine. Inhibition of dopamine allows for an increase in prolactin secretion and concentration (hyperprolactinemia), which leads to inhibition of LH, and in turn leads to anovulation. Inhibition of the HPO axis also results in inhibition of the hypothalamic-pituitary-thyroid (HPT) axis and a decrease in thyroid hormones, in an attempt to minimize energy depletion. This allows the body to focus on survival, rather than reproduction.