quality:corruption, linguistic:paraphrasing
Renaissance period

The new learning of the Renaissance greatly influenced Oxford from the late 15th century onwards. Among university scholars of the period were William Grocyn, who contributed to the revival of Greek language studies, and John Colet, the noted biblical scholar.

With the English Reformation and the breaking of communion with the Roman Catholic Church, recusant scholars from Oxford fled to continental Europe, settling especially at the University of Douai. The method of teaching at Oxford was transformed from the medieval scholastic method to Renaissance education, although institutions associated with the university suffered losses of land and revenues. As a centre of learning and scholarship, Oxford's reputation declined in the Age of Enlightenment; enrolments fell and teaching was neglected.

In 1636, William Laud, the chancellor and Archbishop of Canterbury, codified the university's statutes. These, to a large extent, remained its governing regulations until the mid-19th century. Laud was also responsible for the granting of a charter securing privileges for the University Press, and he made significant contributions to the Bodleian Library, the main library of the university. From the beginnings of the Church of England as the established church until 1866, membership of the church was a requirement to graduate as a Bachelor of Arts, and " dissenters " were only permitted to be promoted to Master of Arts in 1871.

The university was a centre of the Royalist party during the English Civil War (1642–1649), while the town favoured the opposing Parliamentarian cause.

Wadham College, founded in 1610, was the undergraduate college of Sir Christopher Wren. Wren was part of a brilliant group of experimental scientists at Oxford in the 1650s, the Oxford Philosophical Club, which included Robert Boyle and Robert Hooke. This group, which has at times been linked with Boyle's " Invisible College ", held regular meetings at Wadham under the guidance of the college's Warden, John Wilkins, and the group formed the nucleus that went on to found the Royal Society.