structural:reformatting, structural:summarization
Prophase I arrest

Female mammals and birds are born possessing all the oocytes needed for future ovulations, and these oocytes are arrested at the prophase I stage of meiosis. In humans, as an example, oocytes are formed between three and four months of gestation within the fetus and are therefore present at birth. During this prophase I arrested stage (dictyate), which may last for decades, four copies of the genome are present in the oocytes. The arrest of ooctyes at the four genome copy stage was proposed to provide the informational redundancy needed to repair damage in the DNA of the germline. The repair process used appears to involve homologous recombinational repair Prophase I arrested oocytes have a high capability for efficient repair of DNA damage, particularly exogenously induced double-strand breaks. DNA repair capability appears to be a key quality control mechanism in the female germ line and a critical determinant of fertility.