    63 research outputs found

    Do Independent Arab YouTube Broadcasters “Broadcast Themselves”? The Saudi Case Explored

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    The chapter discusses whether YouTube empowers professional amateurs (Pro-Ams) to build the agenda of their channels independently. It also explores the development of YouTube from being a user-dominated platform into an institutionalized medium in its post-Google era. In-depth interviews were conducted with a group of 19-Pro-Ams in Saudi Arabia, representing two YouTube video-producing companies to explore the business model of their channels, how they feel empowered, and how their work is affected by culture, business, and politics. Attempting to re-interview them after 4 years, only one respondent agreed to participate. The results show that the leading YouTube channels in Saudi Arabia attract millions of views monthly. The business model of the channels shows that they are run in a semi-professional style by using personal and advertising funding. The Pro-Ams feel empowered thanks to the routine-free, low cost, and easy-to-use popular platform. They launched their channels to “broadcast” themselves, but with the professionalization and monetization, they had to accommodate the agenda of the audience, the advertisers, and the regime. Eventually, the model was either discontinued or reduced to be an advertising/entrainment platform. The lack of regulations has been always a challenge for these Pro-Ams to get licensed and have a legal standing

    A Knowledge Graph-Based Method for Automating Systematic Literature Reviews

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    Systematic Literature Reviews aim at investigating current approaches to conclude a research gap or determine a futuristic approach. They represent a significant part of a research activity, from which new concepts stem. However, with the massive availability of publications at a rapid growing rate, especially digitally, it becomes challenging to efficiently screen and assess relevant publications. Another challenge is the continuous assessment of related work over a long period of time and the consequent need for a continuous update, which can be a time-consuming task. Knowledge graphs model entities in a connected manner and enable new insights using different reasoning and analysis methods. The objective of this work is to present an approach to partially automate the conduction of a Systematic Literature Review as well as classify and visualize the results as a knowledge graph. The designed software prototype was used for the conduction of a review on context-awareness in automation systems with considerably accurate results compared to a manual conduction.Comment: 9 pages, 7 figures, 2 table

    COVID-19 related complete blood count changes among asymptomatic pregnant women

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    Objective: To evaluate complete blood count (CBC) changes that suggest coronavirus disease-2019 (COVID-19) among asymptomatic pregnant women attending routine antenatal care Methods: A cross-sectional study included 187 healthy pregnant women who were attending the antenatal care clinic of a tertiary University hospital between March and June 2020. After a thorough history and examinations, a venous blood sample was taken from each participant for complete and differential blood counts. Those who showed CBC findings suggestive of COVID-19 were further scheduled for a nasopharyngeal swab for detection of SARS-CoV-2 specific antigens through polymerase chain reaction (PCR). Results: We found 5.3% (n=10) of the study population showed CBC changes that are suggestive of COVID-19. When they were scheduled for nasopharyngeal swab for a PCR confirmatory test, 30% (n=3) of them were PCR positive (which represented 1.6% of the entire study population). The most frequently encountered COVID-19-suggestive change in peripheral blood leukocyte differential counts was leucopenia (100%), followed by decreased eosinophil count (50%), then neutropenia and lymphocytopenia (30%). Conclusions: Certain differential leucocyte count changes (leucopenia, neutropenia, lymphocytopenia and decreased eosinophil count) among asymptomatic pregnant women might be related to COVID-19 infection and may indicate a need for further testing

    The Impacts of Human Resource Management Practices on Company Labor Productivity: Empirical Evidence from Iron and Steel Company in Libya

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    This paper investigates the relationship between human resource management practices  and labor productivity for the iron and steel Libyan company. This paper operationally defined human resource practices as recruitment and selection, training and development, performance appraisal, communication, compensation, teamwork and employment security. Also, productivity measured as labor productivity. The data was collected using the questionnaire that consists of questions with 5-points Likert scales distributed to our samples of 386 employees. By using a stepwise multiple regression analysis, it is found that, all practices had strong positive correlate and effect on each of labor productivity

    Corporate reporting and disclosures in the emerging capital market of Kuwait:the perceptions of users and preparers

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    The objective of this paper is to investigate the perceptions of users and preparers regarding financial disclosure practices in annual reports of Kuwaiti listed firms. To measure participants' views, a questionnaire survey was distributed in Kuwait between October and December 2012, to preparers (financial managers) and users (financial analysts) within Kuwaiti listed companies. The study compares between the perceptions of financial managers and financial analysts regarding disclosing information in corporate annual reports as well as the main obstacles facing the disclosure process and what the problems restricting the use of companies' annual reports. The study also seeks to investigate whether there is a perceived need for improving the usefulness of Kuwaiti companies' annual reports for decision-making. The results, based on 137 responses, indicate that accounting practices in Kuwaiti firms are firmly rooted in a decision-usefulness tradition with management and the board of directors viewed as the key audience for reporting information. Indeed, the annual reports of Kuwaiti listed companies are perceived as the most important sources of information. On the whole both users and preparers shared similar concerns regarding the volume of information contained within annual reports; however, their views differed in terms of identifying potential solutions. The results of the study are likely to have implications for decision makers, the academic community and accounting standard setters. 2018 Macmillan Publishers Ltd., part of Springer Nature

    Virological characteristics of the SARS-CoV-2 Omicron BA.2.75 variant

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    SARS-CoV-2オミクロンBA.2.75株（通称ケンタウロス）のウイルス学的性状の解明. 京都大学プレスリリース. 2022-10-12.The SARS-CoV-2 Omicron BA.2.75 variant emerged in May 2022. BA.2.75 is a BA.2 descendant but is phylogenetically distinct from BA.5, the currently predominant BA.2 descendant. Here, we show that BA.2.75 has a greater effective reproduction number and different immunogenicity profile than BA.5. We determined the sensitivity of BA.2.75 to vaccinee and convalescent sera as well as a panel of clinically available antiviral drugs and antibodies. Antiviral drugs largely retained potency but antibody sensitivity varied depending on several key BA.2.75-specific substitutions. The BA.2.75 spike exhibited a profoundly higher affinity for its human receptor, ACE2. Additionally, the fusogenicity, growth efficiency in human alveolar epithelial cells, and intrinsic pathogenicity in hamsters of BA.2.75 were greater than those of BA.2. Our multilevel investigations suggest that BA.2.75 acquired virological properties independent of BA.5, and the potential risk of BA.2.75 to global health is greater than that of BA.5

    Convergent evolution of SARS-CoV-2 Omicron subvariants leading to the emergence of BQ.1.1 variant

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    In late 2022, various Omicron subvariants emerged and cocirculated worldwide. These variants convergently acquired amino acid substitutions at critical residues in the spike protein, including residues R346, K444, L452, N460, and F486. Here, we characterize the convergent evolution of Omicron subvariants and the properties of one recent lineage of concern, BQ.1.1. Our phylogenetic analysis suggests that these five substitutions are recurrently acquired, particularly in younger Omicron lineages. Epidemic dynamics modelling suggests that the five substitutions increase viral fitness, and a large proportion of the fitness variation within Omicron lineages can be explained by these substitutions. Compared to BA.5, BQ.1.1 evades breakthrough BA.2 and BA.5 infection sera more efficiently, as demonstrated by neutralization assays. The pathogenicity of BQ.1.1 in hamsters is lower than that of BA.5. Our multiscale investigations illuminate the evolutionary rules governing the convergent evolution for known Omicron lineages as of 2022

    Virological characteristics of the SARS-CoV-2 XBB variant derived from recombination of two Omicron subvariants

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    In late 2022, SARS-CoV-2 Omicron subvariants have become highly diversified, and XBB is spreading rapidly around the world. Our phylogenetic analyses suggested that XBB emerged through the recombination of two cocirculating BA.2 lineages, BJ.1 and BM.1.1.1 (a progeny of BA.2.75), during the summer of 2022. XBB.1 is the variant most profoundly resistant to BA.2/5 breakthrough infection sera to date and is more fusogenic than BA.2.75. The recombination breakpoint is located in the receptor-binding domain of spike, and each region of the recombinant spike confers immune evasion and increases fusogenicity. We further provide the structural basis for the interaction between XBB.1 spike and human ACE2. Finally, the intrinsic pathogenicity of XBB.1 in male hamsters is comparable to or even lower than that of BA.2.75. Our multiscale investigation provides evidence suggesting that XBB is the first observed SARS-CoV-2 variant to increase its fitness through recombination rather than substitutions
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