Botox jabs can make you feel depressed: A Cardiff University study  Women who have Botox injections to get rid of laughter lines are more likely to feel depressed – because they can’t smile properly. The treatment, which works by temporarily ‘freezing’ muscles in the face, cuts off the signals sent to the brain when we smile which make us feel happy. It means the treatment may indirectly spark depression. Check out at:http://www.womenfitness.net/news/beauty/botoxJabs_depressed.htm