(CNN) -- Jo-Wilfried Tsonga ended Roger Federer's hopes of winning a record-equaling seventh Wimbledon title on Wednesday as the French 12th seed staged a stunning fightback to reach the semifinals. Federer appeared to be cruising into the last four after winning the first two sets, but Tsonga inflicted the Swiss world No. 3's first defeat from that vantage point in 179 grand slam matches. It was only the third time in the 29-year-old's glittering career that the 16-time grand slam champion had surrendered a two-set lead. Tsonga, ranked 19th in the world, triumphed 3-6 6-7 (3-7) 6-4 6-4 6-4 on Centre Court, serving out to love as he earned a clash with second seed Novak Djokovic. The Serbian, who beat Tsonga in the 2008 Australian Open final, ended the dream run of Australian 18-year-old Bernard Tomic. Tsonga defeated Federer for just the second time in six meetings, their first on grass. "It was amazing. I played unbelievable. It's never easy to come back against Roger. I'm so happy, it's crazy," the 26-year-old told reporters after reaching the semifinals at Wimbledon for the first time. "He's the biggest champion in the sport. He has achieved so much and is the best player in the world. To be two sets down and come back was unbelievable. I served really well. Against Djokovic I will have to come out and do the same again." Federer has now lost in the quarterfinals two years in a row, being beaten by eventual runner-up Tomas Berdych in 2010. "Jo played great. Really from start to finish I don't remember seeing a break point after I broke him in the first game," Federer said. 
The defeat of Federer by Tsonga was the first loss from a two-set lead in how many grand slam matches, and how many times has Roger Federer lost from this same vantage point?
179 and 1