document: in denmark , women planning to conceive are advised to take a daily supplement of 400 g folic acid ( fa ) until the 12th week of gestation to reduce the risk of neural tube defects ( ntds).1 starting fa supplementation before conception is an important component of effective prevention of ntds , since the neural tube closes at gestational week 6 , only a few weeks after the pregnancy may be recognized.2 fa is primarily taken as single supplements or as a component of multivitamins ( mvs ) and other vitamin preparations made for pregnancy planners or pregnant women . despite campaigns promoting the fa recommendation in denmark in 1999 and 2001 , women in the preconceptional period appear to have neither adequate dietary intake of folate nor adequate supplementation from fa tablets or mv supplements . according to the national survey of dietary habits from 2003 to 2008 , only 510% of danish women of fertile age have a sufficient intake of dietary folate.3 the most recent data on periconceptional use of fa supplements in denmark are from the danish national birth cohort ( dnbc ) . between 2000 and 2002 
   , the proportion of fa compliers among dnbc participants who planned their pregnancy increased from 14% to only 22% , and thus remained low even after the campaigns.4,5 several retrospective studies of pregnant women in other countries also reported poor compliance , with 12% of women in the uk,6 17% in norway,7 2330% in australia8,9 and 44% in the us10 reporting fa supplement use in the preconception period . 
   in addition , a prospective cohort study reported that only 6% of the women who became pregnant within 3 months of being interviewed in a general woman s survey in the uk followed the fa recommendation.11 in previous studies , young age , low education and income , smoking , overweight , and parity were reported to be predictors of noncompliance.58,10 to date , no study has examined other health - related predictors of compliance during the preconceptional period , and we lack recent estimates of compliance with the fa recommendation reported from pregnancy planners during the preconceptional period . in the current study , we estimated the prevalence of fa and mv supplement use and identified sociodemographic , lifestyle , reproductive , and medical predictors of such use among danish pregnancy planners . 
   the present study was a cross - sectional analysis of baseline data from an internet - based prospective cohort study of danish pregnancy planners  snart - gravid ( soon pregnant).the study design has been described in detail elsewhere.12,13 briefly , the study was initiated in june 2007 . 
   participants were enrolled via the study website , and data were collected by email and self - administered questionnaires . 
   recruitment was achieved by a pop - up advertisement placed on a well - known health - related website ( http://www.netdoktor.dk ) and two press releases . before enrolment 
   , potential participants entering the study website were required to read a consent form and fill in a screening questionnaire in order to confirm eligibility . 
   further , participants were required to provide a valid email address and their personal civil registry ( cpr ) number , which is a unique ten - digit personal identification number allowing linkage to a number of nationwide registries . 
   eligible women were invited to complete a baseline questionnaire and bimonthly follow - up questionnaires for 12 months or until conception occurred , after which active follow - up ended . 
   participants were initially randomized to receive either a short- or a long - form baseline questionnaire . 
   completion rates and missing data were similar for both questionnaire versions.13 eligible women were danish residents aged 1840 years , living in a stable relationship with a male partner , not using birth control , not receiving any type of fertility treatment , and attempting to conceive for no more than 12 months . from june 1 , 2007 to august 3 , 2011 
   of these , one woman did not provide a valid cpr number in the screener , one woman was excluded because she was already pregnant ( 14 weeks ) , and 533 women were excluded because they had been attempting to conceive for more than 12 months . in total , 5383 eligible women enrolled in the study during the 4-year study period . 
   data on preconceptional use of fa and mv supplements and sociodemographic , lifestyle , reproductive , and medical variables were assessed at baseline . in the baseline questionnaire , women were asked  do you take vitamins on a regular basis  daily or almost every day ?  ,  how long have you been taking vitamins on a regular basis 
   less than one year , 15 years , more than 5 years , or do nt know ?  , and  which of the following vitamins or minerals do you take on a regular basis 
   mvs , vitamin a , beta - carotene , vitamin b , vitamin c , vitamin d , vitamin e , fa , calcium , magnesium , selenium , or other ?  participants who reported  multivitamin  or wrote the name of an mv product were defined 
   similarly , participants who reported  folic acid  or wrote  folate  were defined 
   users  were defined as women who used either fa supplements , mv supplements , or both . 
   women who used single - vitamin or mineral supplements other than fa and women who did not take any dietary supplements were defined  nonusers . 
   a total of 197 ( 3.7% ) women did not answer the initial vitamin question and were also defined as nonusers . 
   participants reported weight , height , physical activity , and smoking history in the baseline questionnaire , allowing the calculation of body mass index ( bmi ) , total metabolic equivalents ( mets ) , and pack - years of smoking . 
   bmi was calculated by dividing weight ( kg ) with height squared ( m ) . 
   mets were estimated by summing the mets from moderate and vigorous physical activity ( hours per week multiplied by 3.5 and hours per week multiplied by 7.0 , respectively).14 data on smoking were categorized as pack - years of ever - smoking where 1 pack - year was defined as smoking 20 cigarettes per day in 1 year . to assess sociodemographic predictors of compliance among pregnancy planners , we examined the association between preconceptional fa or mv supplement use and the following variables : age ( categorized as < 25 , 2529 , 3034 , and 35 years ) , schooling ( primary and lower secondary school , high school , and other ) , vocational training ( none , short [ <3 years ] , medium [ 34 years ] , and long [ > 4 years ] ) and total monthly household income ( < 12,500 , 12,50024,999 , 25,00039,999 , 40,00064,999 , and 65,000 dkk / month ) . 
   we also examined lifestyle factors that could indicate intense efforts to conceive , such as intercourse frequency ( categorized as < 1 , 13 , and 4 times per week ) and months attempting pregnancy at study entrance ( 01 , 24 , 56 , and 712 months ) . 
   furthermore , compliance with other health recommendations , such as attending the national screening program for cervical cancer ( pap smear ) during the last 3 years ( none vs one or more ) , smoking history ( never smoked , < 5 , 59 , and 10 pack - years ) , current alcohol intake ( none , 13 , 47 , 814 , and 15 
   drinks / week ) , bmi ( < 18.5 , 18.524.9 , 2529.9 , 3034.9 , and 35 kg / m ) , and engagement in physical activity ( < 10 , 1019 , 2039 , and 40 mets / week ) , were also of interest . finally , we studied the associations with previous spontaneous abortion ( yes vs no ) , parity ( nulliparous vs parous ) , and medical conditions that may increase health awareness in relation to pregnancy , which included hypertension ( yes vs no ) , diabetes ( yes vs no ) , thyroid disease ( yes vs no ) , pelvic inflammatory disease ( yes vs no ) , and infection with chlamydia ( yes vs no ) . 
   we estimated the prevalence proportion ( pp ) of fa or mv users in each level of study predictors . 
   multivariate binomial regression was used to obtain prevalence proportion differences ( ppds ) with 95% confidence intervals ( cis ) for each predictor level in relation to the reference group . 
   the multivariate analyses for the pp and ppd for each study predictor were adjusted for all other covariates . 
   stata statistical software ( version 11.2 ; college station , texas ) was used for all analyses . 
   missing values ranged between 0.1% ( schooling ) and 8.7% ( total monthly household income ) . 
   because 1540 ( 28.6% ) participants were initially randomized to receive the short - form baseline questionnaire , they did not receive the questions about hypertension , diabetes , thyroid disease , and pelvic inflammatory disease . 
   the present study was a cross - sectional analysis of baseline data from an internet - based prospective cohort study of danish pregnancy planners  snart - gravid ( soon pregnant).the study design has been described in detail elsewhere.12,13 briefly , the study was initiated in june 2007 . 
   participants were enrolled via the study website , and data were collected by email and self - administered questionnaires . 
   recruitment was achieved by a pop - up advertisement placed on a well - known health - related website ( http://www.netdoktor.dk ) and two press releases . before enrolment 
   , potential participants entering the study website were required to read a consent form and fill in a screening questionnaire in order to confirm eligibility . 
   further , participants were required to provide a valid email address and their personal civil registry ( cpr ) number , which is a unique ten - digit personal identification number allowing linkage to a number of nationwide registries . 
   eligible women were invited to complete a baseline questionnaire and bimonthly follow - up questionnaires for 12 months or until conception occurred , after which active follow - up ended . 
   participants were initially randomized to receive either a short- or a long - form baseline questionnaire . 
   eligible women were danish residents aged 1840 years , living in a stable relationship with a male partner , not using birth control , not receiving any type of fertility treatment , and attempting to conceive for no more than 12 months . from june 1 , 2007 to august 3 , 2011 
   of these , one woman did not provide a valid cpr number in the screener , one woman was excluded because she was already pregnant ( 14 weeks ) , and 533 women were excluded because they had been attempting to conceive for more than 12 months . in total , 5383 eligible women enrolled in the study during the 4-year study period . 
   data on preconceptional use of fa and mv supplements and sociodemographic , lifestyle , reproductive , and medical variables were assessed at baseline . 
   in the baseline questionnaire , women were asked  do you take vitamins on a regular basis  daily or almost every day ?  ,  how long have you been taking vitamins on a regular basis 
   less than one year , 15 years , more than 5 years , or do nt know ?  , and  which of the following vitamins or minerals do you take on a regular basis 
   mvs , vitamin a , beta - carotene , vitamin b , vitamin c , vitamin d , vitamin e , fa , calcium , magnesium , selenium , or other ?  participants who reported  multivitamin  or wrote the name of an mv product were defined 
   similarly , participants who reported  folic acid  or wrote  folate  were defined 
   users  were defined as women who used either fa supplements , mv supplements , or both . 
   women who used single - vitamin or mineral supplements other than fa and women who did not take any dietary supplements were defined  nonusers . 
   a total of 197 ( 3.7% ) women did not answer the initial vitamin question and were also defined as nonusers . 
   participants reported weight , height , physical activity , and smoking history in the baseline questionnaire , allowing the calculation of body mass index ( bmi ) , total metabolic equivalents ( mets ) , and pack - years of smoking . 
   bmi was calculated by dividing weight ( kg ) with height squared ( m ) . 
   mets were estimated by summing the mets from moderate and vigorous physical activity ( hours per week multiplied by 3.5 and hours per week multiplied by 7.0 , respectively).14 data on smoking were categorized as pack - years of ever - smoking where 1 pack - year was defined as smoking 20 cigarettes per day in 1 year . to assess sociodemographic predictors of compliance among pregnancy planners , we examined the association between preconceptional fa or mv supplement use and the following variables : age ( categorized as < 25 , 2529 , 3034 , and 35 years ) , schooling ( primary and lower secondary school , high school , and other ) , vocational training ( none , short [ <3 years ] , medium [ 34 years ] , and long [ > 4 years ] ) and total monthly household income ( < 12,500 , 12,50024,999 , 25,00039,999 , 40,00064,999 , and 65,000 dkk / month ) . 
   we also examined lifestyle factors that could indicate intense efforts to conceive , such as intercourse frequency ( categorized as < 1 , 13 , and 4 times per week ) and months attempting pregnancy at study entrance ( 01 , 24 , 56 , and 712 months ) . 
   furthermore , compliance with other health recommendations , such as attending the national screening program for cervical cancer ( pap smear ) during the last 3 years ( none vs one or more ) , smoking history ( never smoked , < 5 , 59 , and 10 pack - years ) , current alcohol intake ( none , 13 , 47 , 814 , and 15 drinks / week ) , bmi ( < 18.5 , 18.524.9 , 2529.9 , 3034.9 , and 35 kg / m ) , and engagement in physical activity ( < 10 , 1019 , 2039 , and 40 mets / week ) , were also of interest . finally , we studied the associations with previous spontaneous abortion ( yes vs no ) , parity ( nulliparous vs parous ) , and medical conditions that may increase health awareness in relation to pregnancy , which included hypertension ( yes vs no ) , diabetes ( yes vs no ) , thyroid disease ( yes vs no ) , pelvic inflammatory disease ( yes vs no ) , and infection with chlamydia ( yes vs no ) . 
   we estimated the prevalence proportion ( pp ) of fa or mv users in each level of study predictors . 
   multivariate binomial regression was used to obtain prevalence proportion differences ( ppds ) with 95% confidence intervals ( cis ) for each predictor level in relation to the reference group . 
   the multivariate analyses for the pp and ppd for each study predictor were adjusted for all other covariates . 
   stata statistical software ( version 11.2 ; college station , texas ) was used for all analyses . missing values ranged between 0.1% ( schooling ) and 8.7% ( total monthly household income ) . because 1540 ( 28.6% ) participants were initially randomized to receive the short - form baseline questionnaire 
   , they did not receive the questions about hypertension , diabetes , thyroid disease , and pelvic inflammatory disease . 
   overall , 412 ( 7.7% ) women used fa supplements exclusively , 1100 ( 20.4% ) used mv supplements exclusively , and 1831 ( 34.0% ) used both , yielding 62.1% users . 
   a total of 82 ( 1.5% ) used single vitamins or minerals other than fa , and 1958 ( 36.4% ) did not use any dietary supplements , yielding 2040 ( 37.9% ) nonusers of fa or mv supplements ( table 1 ) . among users , 
   after mutual adjustment for covariates , higher age was associated with increased prevalence of fa or mv use ( table 2 ) . 
   our data also indicate that women who finished high school were more likely to use fa or mvs compared with women with less schooling . 
   similarly , compared with women with a long vocational training ( > 4 years ) , ppds for having no vocational training and a short ( <3 years ) vocational training were 5.7% and 7.1% , respectively , and compared with total monthly household of 65,000 dkk / month , ppd for < 12,500 dkk / month was 8.7% . while intercourse frequency  1 times / week was associated with an increased prevalence of fa or mv use , there was no clear association between months attempting to conceive at study entrance and fa or mv use . 
   furthermore , women who had pap smears once or more during the last 3 years were more likely to use fa or mv supplements compared with women who did not have pap smears ( ppd was 9.7% for none versus one or more ) . 
   kg / m ) were associated with a decreased prevalence of fa or mv use . compared with women who never smoked , 
   ppd for 10 pack - years of smoking was 11.3% . compared with no alcohol intake ppd for 15 drinks / week was 18.4% . compared with normal weight ( bmi = 18.524.9 kg / m ) , 
   ppds of fa or mv use for bmis of 3034.9 and 35 kg / m were 5.1% and 7.1% , respectively . 
   furthermore , women who engaged in physical activity were more likely to use fa or mvs than sedentary women ( < 10 mets / week ) . among women who had a previous spontaneous abortion , 
   the ppd of fa or mv use was 7.7% higher than women who did not report having a previous abortion . 
   finally , there was no clear association between being diagnosed with either hypertension , diabetes , thyroid disease , pelvic inflammatory disease , or infections with chlamydia and preconceptional fa or mv supplement use . 
   our data indicate that 62% of the 5383 pregnancy planners in this study adhere to the danish fa recommendation . by interpreting 
   users  as compliers , we may overestimate the proportion of compliers following the fa recommendation . the questionnaire provided information on whether the women took an fa or mv supplement or not , but there was no information on the exact dose of fa ingested or the brand name of the fa or mv product . in addition , 
   mv supplements have no standard definitions,1720 it can not be assumed that all mvs contained fa . however , most mvs on the danish market contain 400 g fa , especially those made for use during pregnancy . 
   the prevalence among pregnancy planners in our study is higher than the prevalence of preconception fa ( 12%44%)510 and mv use ( 11%)8 reported by pregnant women in previous studies . however , these studies collected data during the second and third trimesters , which may decrease the recall of fa and mv use during the preconceptional period . in addition , the studies were relatively small , with 588 women attending an antenatal clinic in melbourne in gestational weeks 3638,8 1541 women attending an antenatal ultrasound screening in gestational weeks 1719 in oslo,7 and 327 pregnant women calling the california teratogen information service in gestational week 13 in the us.10 consequently , prevalence estimates reported in these studies may have been imprecise . 
   the definition of compliance with the fa recommendation differs among studies . in the study by forster 
   et al,8 29% took prepregnancy fa supplements , but only 23% reported taking fa for at least 4 weeks before pregnancy . in the study by braekke and staff,7 17% of 
   this proportion may be more comparable with our findings , since some  users  in our study may have been in gestational weeks 04 at baseline . 
   women with unplanned pregnancies are less likely to use fa supplements before pregnancy . in the studies by forster 
   et al8 and goldberg et al,10 the prevalence of unplanned pregnancy was 19% and 36% , respectively . 
   these studies estimated fa use among all pregnancies ( planned and unplanned ) , making their results difficult to compare with ours . in the study by braekke and staff,7 there was no information about unplanned pregnancies or contributions of fa from mv supplements , both increasing the possibility of underestimation of the proportions of fa users in this study . in denmark , the largest and most recent study of lifestyle factors in relation to compliance with the fa recommendation was conducted among 18,294 pregnant women ( gestational weeks 1012 ) enrolled in the dnbc during 20002002.5 in this study , fa supplements were derived from single fa tablets , mv tablets , and vitamins made for pregnant or lactating women . 
   compliance was defined as taking 320 g fa per day , from 4 weeks before the date of the last menstrual period until gestation week 6 . 
   a total of 76% of the pregnancies were planned , and the overall proportion of women who complied with the recommendation was only 16% among planners . during the 10-year time period to the present study , there may have been an increase in the awareness as well as more available information about prepregnant recommendations , which may partly explain the observed increase in the prevalence of compliers with the fa recommendation found in this study . 
   in contrast to the dnbc , our data on supplement use and potential predictors were reported during the preconceptional period , and information was recorded prospectively , which increases the validity of the study . on the other hand , snart - gravid study participants may be more health - conscious than the general population of pregnancy planners , possibly overestimating the prevalence of fa or mv use . 
   even so , it is unlikely that an overestimation of supplement use would meaningfully distort the associations between predictors and fa or mv use . 
   in addition , differences in sociodemographic factors among snart - gravid study participants compared with the general population may also contribute to an overestimation of fa or mv use . 
   our study agrees with previous studies that found that maternal age,5,7,10 education,5,6,10 income,6,8 smoking,5,8 and bmi10 were associated with preconception fa use . 
   although a history of childbirth may increase awareness of preconceptional fa use , previous studies found that a previous childbirth either decreased the likelihood of fa use in subsequent pregnancies or was not related to fa use.5,7,8 we found only little association between parity and fa use in our study . 
   the positive associations between previous spontaneous abortion and intercourse frequency and fa or mv use found in our study have not been reported previously . 
   these findings may indicate a relation between a high desire to conceive and increased knowledge about the preconceptional fa guidelines . while lifestyle recommendations during pregnancy are widely available , less advice is available for women trying to conceive . 
   in addition to the fa recommendation , danish women planning a pregnancy are advised to avoid alcohol altogether.1 a total of 32% reported no alcohol intake in our study , which was slightly more than the 12% reported from the dnbc previously.21 in addition , we found the lowest proportion of fa or mv users among women with the highest alcohol intake . 
   together with the concern that excessive alcohol intake impedes the normal bioavailability and metabolism of folate,22 these results underscore the need to target women at high risk of not following the fa recommendation , as well as those not following other preconceptional guidelines . 
   being diagnosed with a chronic disease has previously been associated with increased dietary supplement use in general.23 pregnancy planners with a chronic illness might be more prone to use fa or mvs because of increased health awareness , but we found little association between a diagnosis of hypertension , diabetes , thyroid disease , pelvic inflammatory disease or infections with chlamydia and preconceptional use of fa or mvs . 
   our data indicate that 62% of the 5383 pregnancy planners in this study adhere to the danish fa recommendation . by interpreting 
   users  as compliers , we may overestimate the proportion of compliers following the fa recommendation . the questionnaire provided information on whether the women took an fa or mv supplement or not , but there was no information on the exact dose of fa ingested or the brand name of the fa or mv product . in addition , 
   mv supplements have no standard definitions,1720 it can not be assumed that all mvs contained fa . however , most mvs on the danish market contain 400 g fa , especially those made for use during pregnancy . 
   the prevalence among pregnancy planners in our study is higher than the prevalence of preconception fa ( 12%44%)510 and mv use ( 11%)8 reported by pregnant women in previous studies . however , these studies collected data during the second and third trimesters , which may decrease the recall of fa and mv use during the preconceptional period . in addition , the studies were relatively small , with 588 women attending an antenatal clinic in melbourne in gestational weeks 3638,8 1541 women attending an antenatal ultrasound screening in gestational weeks 1719 in oslo,7 and 327 pregnant women calling the california teratogen information service in gestational week 13 in the us.10 consequently , prevalence estimates reported in these studies may have been imprecise . 
   the definition of compliance with the fa recommendation differs among studies . in the study by forster 
   et al,8 29% took prepregnancy fa supplements , but only 23% reported taking fa for at least 4 weeks before pregnancy . in the study by braekke and staff,7 17% of 
   this proportion may be more comparable with our findings , since some  users  in our study may have been in gestational weeks 04 at baseline . 
   women with unplanned pregnancies are less likely to use fa supplements before pregnancy . in the studies by forster 
   et al8 and goldberg et al,10 the prevalence of unplanned pregnancy was 19% and 36% , respectively . 
   these studies estimated fa use among all pregnancies ( planned and unplanned ) , making their results difficult to compare with ours . in the study by braekke and staff,7 there was no information about unplanned pregnancies or contributions of fa from mv supplements , both increasing the possibility of underestimation of the proportions of fa users in this study . in denmark , the largest and most recent study of lifestyle factors in relation to compliance with the fa recommendation was conducted among 18,294 pregnant women ( gestational weeks 1012 ) enrolled in the dnbc during 20002002.5 in this study , fa supplements were derived from single fa tablets , mv tablets , and vitamins made for pregnant or lactating women . 
   compliance was defined as taking 320 g fa per day , from 4 weeks before the date of the last menstrual period until gestation week 6 . 
   a total of 76% of the pregnancies were planned , and the overall proportion of women who complied with the recommendation was only 16% among planners . during the 10-year time period to the present study , there may have been an increase in the awareness as well as more available information about prepregnant recommendations , which may partly explain the observed increase in the prevalence of compliers with the fa recommendation found in this study . 
   in contrast to the dnbc , our data on supplement use and potential predictors were reported during the preconceptional period , and information was recorded prospectively , which increases the validity of the study . on the other hand , snart - gravid study participants may be more health - conscious than the general population of pregnancy planners , possibly overestimating the prevalence of fa or mv use . 
   even so , it is unlikely that an overestimation of supplement use would meaningfully distort the associations between predictors and fa or mv use . 
   in addition , differences in sociodemographic factors among snart - gravid study participants compared with the general population may also contribute to an overestimation of fa or mv use . 
   our study agrees with previous studies that found that maternal age,5,7,10 education,5,6,10 income,6,8 smoking,5,8 and bmi10 were associated with preconception fa use . 
   although a history of childbirth may increase awareness of preconceptional fa use , previous studies found that a previous childbirth either decreased the likelihood of fa use in subsequent pregnancies or was not related to fa use.5,7,8 we found only little association between parity and fa use in our study . 
   the positive associations between previous spontaneous abortion and intercourse frequency and fa or mv use found in our study have not been reported previously . 
   these findings may indicate a relation between a high desire to conceive and increased knowledge about the preconceptional fa guidelines . while lifestyle recommendations during pregnancy are widely available , less advice is available for women trying to conceive . 
   in addition to the fa recommendation , danish women planning a pregnancy are advised to avoid alcohol altogether.1 a total of 32% reported no alcohol intake in our study , which was slightly more than the 12% reported from the dnbc previously.21 in addition , we found the lowest proportion of fa or mv users among women with the highest alcohol intake . together with the concern that excessive alcohol intake impedes the normal bioavailability and metabolism of folate,22 these results 
   underscore the need to target women at high risk of not following the fa recommendation , as well as those not following other preconceptional guidelines . 
   being diagnosed with a chronic disease has previously been associated with increased dietary supplement use in general.23 pregnancy planners with a chronic illness might be more prone to use fa or mvs because of increased health awareness , but we found little association between a diagnosis of hypertension , diabetes , thyroid disease , pelvic inflammatory disease or infections with chlamydia and preconceptional use of fa or mvs . 
   our findings indicate that more than one - third of the pregnancy planners in this study do not follow the preconceptional fa recommendation . 
   we found that pregnancy planners with other risky behaviors , such as smoking and alcohol use , obesity , and being physically inactive , are less likely to comply with the fa recommendation or use mvs .
summary: purposecompliance with the danish preconceptional folic acid ( fa ) recommendation  a daily supplement of 400 g  is reported to be poor . 
   uncertainty remains , however , about the prevalence of compliers and health - related predictors of compliance in the preconceptional period.methodswe used self - reported baseline data from 5383 women , aged 1840 years , enrolled in an internet - based prospective cohort study of danish pregnancy planners during 20072011 . 
   we estimated the prevalence proportions of fa or multivitamin ( mv ) use in relation to selected sociodemographic , lifestyle , reproductive , and medical characteristics . 
   multivariate binomial regression was used to obtain prevalence proportion differences with 95% confidence intervals for each level of study predictors , adjusted for all other predictors.resultsoverall , 7.7% of women used fa supplements , 20.4% used mv supplements , 34.0% used both , 1.5% used other single vitamins or minerals , and 36.4% did not use any dietary supplements . 
   the prevalence of fa or mv supplement use was higher among older women , women with higher education and income , and women with healthy lifestyle factors such as being a nonsmoker , nondrinker , physically active , maintaining a normal body mass index and having regular pap smears . 
   greater intercourse frequency and a history of spontaneous abortion were also positively associated with fa or mv supplement use . 
   we found no clear association between use of fa or mv supplements and a diagnosis of hypertension , diabetes , thyroid disease , pelvic inflammatory disease , or chlamydia.conclusiona large proportion of pregnancy planners do not use fa or mv supplements . 
   pregnancy planners with generally risky lifestyle behaviors are less likely to comply with the fa recommendation .