The matches were originally scheduled for 7–13 October and 11–17 November 2020. However, CONCACAF announced on 8 September 2020 that the matches would be postponed, and would not begin until March 2021. The schedule for the March 2021 matches was announced on 26 February 2021. Due to the COVID-19 pandemic in North America and related quarantine and travel restrictions in certain countries, some matches took place at a neutral venue outside the territory of the host association.