From f.harrell at vanderbilt.edu  Sun Jan 11 16:21:23 2009
From: f.harrell at vanderbilt.edu (Frank E Harrell Jr)
Date: Sun, 11 Jan 2009 09:21:23 -0600
Subject: [Rd] NY Times article
Message-ID: <496A0E73.2020805@vanderbilt.edu>

Nicholas please note that FDA does not require type III sums of squares, 
LOCF, and the use of any particular software.  It is just the fact that 
FDA does not disallow type III tests and LOCF that prevents pharma from 
abandoning these terrible methods.

Frank
-- 
Frank E Harrell Jr   Professor and Chair           School of Medicine
                      Department of Biostatistics   Vanderbilt University



[Rd] NY Times article
Frank E Harrell Jr