chunk: Ed Saxon (Jeff Daniels), a college professor, wakes up to find his wife has not returned home. He takes some mysterious pills, then calls one of his wife's friends, Susie (Molly Price), confusedly asking whether he should be worried. Susie suggests that he call the local hospital, but they have no record of his wife being admitted. After further consulting Susie, he decides to call the police. When Detective Derm (Gil Bellows) arrives, Derm takes pills similar to Saxon's. They check her workplace and listen to some messages on the answering machine. George Simian (Julian McMahon) has left a message, inquiring about his wife, and Derm remarks that her abandoned car was found near Simian's house. Saxon also has to deal with the college, annoyed that he didn't show up to teach his class, which leads one of his students, Sadie (Emily Bergl), to also leave a message.