text: Convolutional networks (ConvNets) have achieved great successes in various challenging vision tasks. However, the performance of ConvNets would degrade when encountering the domain shift. The domain adaptation is more significant while challenging in the field of biomedical image analysis, where cross-modality data have largely different distributions. Given that annotating the medical data is especially expensive, the supervised transfer learning approaches are not quite optimal. In this paper, we propose an unsupervised domain adaptation framework with adversarial learning for cross-modality biomedical image segmentations. Specifically, our model is based on a dilated fully convolutional network for pixel-wise prediction. Moreover, we build a plug-and-play domain adaptation module (DAM) to map the target input to features which are aligned with source domain feature space. A domain critic module (DCM) is set up for discriminating the feature space of both domains. We optimize the DAM and DCM via an adversarial loss without using any target domain label. Our proposed method is validated by adapting a ConvNet trained with MRI images to unpaired CT data for cardiac structures segmentations, and achieved very promising results.
  @cite_18: 
  @cite_11: 
  @cite_9: Recent reports suggest that a generic supervised deep CNN model trained on a large-scale dataset reduces, but does not remove, dataset bias on a standard benchmark. Fine-tuning deep models in a new domain can require a significant amount of data, which for many applications is simply not available. We propose a new CNN architecture which introduces an adaptation layer and an additional domain confusion loss, to learn a representation that is both semantically meaningful and domain invariant. We additionally show that a domain confusion metric can be used for model selection to determine the dimension of an adaptation layer and the best position for the layer in the CNN architecture. Our proposed adaptation method offers empirical performance which exceeds previously published results on a standard benchmark visual domain adaptation task.
  @cite_21: Deep neural networks are able to learn powerful representations from large quantities of labeled input data, however they cannot always generalize well across changes in input distributions. Domain adaptation algorithms have been proposed to compensate for the degradation in performance due to domain shift. In this paper, we address the case when the target domain is unlabeled, requiring unsupervised adaptation. CORAL is a "frustratingly easy" unsupervised domain adaptation method that aligns the second-order statistics of the source and target distributions with a linear transformation. Here, we extend CORAL to learn a nonlinear transformation that aligns correlations of layer activations in deep neural networks (Deep CORAL). Experiments on standard benchmark datasets show state-of-the-art performance.
  @cite_3: Adversarial learning methods are a promising approach to training robust deep networks, and can generate complex samples across diverse domains. They also can improve recognition despite the presence of domain shift or dataset bias: several adversarial approaches to unsupervised domain adaptation have recently been introduced, which reduce the difference between the training and test domain distributions and thus improve generalization performance. Prior generative approaches show compelling visualizations, but are not optimal on discriminative tasks and can be limited to smaller shifts. Prior discriminative approaches could handle larger domain shifts, but imposed tied weights on the model and did not exploit a GAN-based loss. We first outline a novel generalized framework for adversarial adaptation, which subsumes recent state-of-the-art approaches as special cases, and we use this generalized view to better relate the prior approaches. We propose a previously unexplored instance of our general framework which combines discriminative modeling, untied weight sharing, and a GAN loss, which we call Adversarial Discriminative Domain Adaptation (ADDA). We show that ADDA is more effective yet considerably simpler than competing domain-adversarial methods, and demonstrate the promise of our approach by exceeding state-of-the-art unsupervised adaptation results on standard cross-domain digit classification tasks and a new more difficult cross-modality object classification task.
  @cite_0: 
  @cite_13: We introduce a new representation learning approach for domain adaptation, in which data at training and test time come from similar but different distributions. Our approach is directly inspired by the theory on domain adaptation suggesting that, for effective domain transfer to be achieved, predictions must be made based on features that cannot discriminate between the training (source) and test (target) domains. The approach implements this idea in the context of neural network architectures that are trained on labeled data from the source domain and unlabeled data from the target domain (no labeled target-domain data is necessary). As the training progresses, the approach promotes the emergence of features that are (i) discriminative for the main learning task on the source domain and (ii) indiscriminate with respect to the shift between the domains. We show that this adaptation behaviour can be achieved in almost any feed-forward model by augmenting it with few standard layers and a new gradient reversal layer. The resulting augmented architecture can be trained using standard backpropagation and stochastic gradient descent, and can thus be implemented with little effort using any of the deep learning packages. We demonstrate the success of our approach for two distinct classification problems (document sentiment analysis and image classification), where state-of-the-art domain adaptation performance on standard benchmarks is achieved. We also validate the approach for descriptor learning task in the context of person re-identification application.
  @cite_12: 
  @cite_17: In recent years, supervised learning with convolutional networks (CNNs) has seen huge adoption in computer vision applications. Comparatively, unsupervised learning with CNNs has received less attention. In this work we hope to help bridge the gap between the success of CNNs for supervised learning and unsupervised learning. We introduce a class of CNNs called deep convolutional generative adversarial networks (DCGANs), that have certain architectural constraints, and demonstrate that they are a strong candidate for unsupervised learning. Training on various image datasets, we show convincing evidence that our deep convolutional adversarial pair learns a hierarchy of representations from object parts to scenes in both the generator and discriminator. Additionally, we use the learned features for novel tasks - demonstrating their applicability as general image representations.
summary: Most prior studies on unsupervised domain adaptation focused on aligning the distributions between domains in feature space, by minimizing measures of distance between features extracted from the source and target domains. For example, the Maximum Mean Discrepancy (MMD) was minimized together with a task-specific loss to learn the domain-invariant and semantic-meaningful features in @cite_9 . The correlations of layer activations between the domains were aligned in the study of @cite_21 . Based on this, @cite_0 further extended the work and minimized domain difference based on both the first and second order information between source and target domains. Alternatively, with the emergence of generative adversarial network (GAN) @cite_11 and its powerful extensions @cite_17 @cite_18 , the mapping between domains were implicitly learned via the adversarial loss. The @cite_13 proposed to extract domain-invariant features by sharing weights between two ConvNet classifiers. Later, the @cite_3 introduced a more flexible adversarial learning method with untied weight sharing, which helps effective learning in the presence of larger domain shifts. Another GAN based direction of solution is to learn a transformation in the pixel space @cite_12 , adapting the source-domain images to appear as if drawn from the target domain.