Oliveira mødte [[Clay Guida]] på [[UFC 225]], hvor han erstattede en skadet [[Bobby Green]].<ref>{{Cite web|url=http://www.chicagotribune.com/sports/breaking/ct-spt-ufc-clay-guida-bobby-green-20180417-story.html|title=Round Lake's Clay Guida faces Bobby Green in UFC 225 battle of little bigmouths |publisher=chicagotribine.com|author=Phil Thompson|date=2018-04-17|access-date=2018-04-17}}</ref> Han vandt via guillotine choke submission i 1. omgang.<ref>{{Cite news|url=https://mmajunkie.com/2018/06/ufc-225-results-charles-oliveira-spoils-clay-guidas-chicago-homecoming-ties-royce-gracie-record|title=UFC 225 results: Charles Oliveira spoils Clay Guida's homecoming, ties Royce Gracie record|date=2018-06-09|work=MMAjunkie|access-date=2018-06-10|language=en-US}}</ref> Sejren gav ham sin 5. ''Performance of the Night'' bonus.<ref>{{Cite web|url=http://www.sherdog.com/news/news/UFC-225-Bonuses-Whittaker-Romero-Garner-Fight-of-the-Night-Honors-for-Classic-Battle-137929|title=UFC 225 Bonuses: Whittaker, Romero Garner ‘Fight of the Night’ Honors for Classic Battle|last=Sherdog.com|website=Sherdog|access-date=2018-06-10}}</ref>
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