En stor del af modulerne er udviklet af universitetsstuderende som en opgave i forbindelse med et kursus. Derudover er flere eksisterende sider fusioneret med ChemWiki, blandt andet thechemblogs projekt "The Chem Wiki"<ref>The Chem Wiki to merge with…. the Chemwiki 3. august 2009 http://www.thechemblog.com/?p=1508</ref>, Charles Ophardts "Virtual ChemBook", Stephen Lowers "Chem1 Virtual Textbook", William Reuschs "Virtual Textbook of Organic Chemistry" og Tim Soderbergs "Organic Chemistry With a Biological Emphasis"<ref>{{cite web|title=UC Davis chemwiki continues to integrate and expand, The Sacramento Aggie|date=2010-10-21|url=http://theaggie.org/article/2010/10/21/uc-davis-chemwiki-continues-to-integrate-and-expand}}</ref>.
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