{| class="wikitable" style="margin-left:1em; text-align:center;"
! style="width:70px;"|Seedning
! style="width:60px;"|Rang.<ref name="wta">Sum af spillernes rangering på [[WTA's verdensrangliste]] pr. [[. august]] [[2021]].</ref>
! Spillere
! Resultat
|-
| '''1'''
| 3
| style="text-align:left; padding-left:5px; padding-right:20px;"|{{flagikon|TPE|3:2}} [[Hsieh Su-Wei]]<br/>{{flagikon|BEL|3:2}} [[Elise Mertens]]
| style="text-align:left; padding-left:7px; padding-right:20px;"|Kvartfinalister
|-
| '''2'''
| 7
| style="text-align:left; padding-left:5px; padding-right:20px;"|{{flagikon|CZE|3:2}} [[Barbora Krejčíková]]<br/>{{flagikon|CZE|3:2}} [[Kateřina Siniaková]]
| style="text-align:left; padding-left:7px; padding-right:20px;"|Første runde
|-
| '''3'''
| 18
| style="text-align:left; padding-left:5px; padding-right:20px;"|{{flagikon|JPN|3:2}} [[Shuko Aoyama]]<br/>{{flagikon|JPN|3:2}} [[Ena Shibahara]]
| style="text-align:left; padding-left:7px; padding-right:20px;"|Tredje runde
|-
| '''4'''
| 25
| style="text-align:left; padding-left:5px; padding-right:20px;"|{{flagikon|USA|3:2}} [[Nicole Melichar-Martinez]]<br/>{{flagikon|NED|3:2}} [[Demi Schuurs]]
| style="text-align:left; padding-left:7px; padding-right:20px;"|Første runde
|-
| '''5'''
| 28
| style="text-align:left; padding-left:5px; padding-right:20px;"|{{flagikon|CAN|3:2}} [[Gabriela Dabrowski]]<br/>{{flagikon|BRA|3:2}} [[Luisa Stefani]]
| style="text-align:left; padding-left:7px; padding-right:20px;"|Semifinalister
|-
| '''6'''
| 29
| style="text-align:left; padding-left:5px; padding-right:20px;"|{{flagikon|RUS|3:2}} [[Veronika Kudermetova]]<br/>{{flagikon|USA|3:2}} [[Bethanie Mattek-Sands]]
| style="text-align:left; padding-left:7px; padding-right:20px;"|Tredje runde
|-
| '''7'''
| 35
| style="text-align:left; padding-left:5px; padding-right:20px;"|{{flagikon|CHI|3:2}} [[Alexa Guarachi]]<br/>{{flagikon|USA|3:2}} [[Desirae Krawczyk]]
| style="text-align:left; padding-left:7px; padding-right:20px;"|Semifinalister
|-
| '''8'''
| 47
| style="text-align:left; padding-left:5px; padding-right:20px;"|{{flagikon|CRO|3:2}} [[Darija Jurak]]<br/>{{flagikon|SLO|3:2}} [[Andreja Klepač]]
| style="text-align:left; padding-left:7px; padding-right:20px;"|Tredje runde
|-
| '''9'''
| 57
| style="text-align:left; padding-left:5px; padding-right:20px;"|{{flagikon|LAT|3:2}} [[Jeļena Ostapenko]]<br/>{{flagikon|RUS|3:2}} [[Vera Zvonarjova]]
| style="text-align:left; padding-left:7px; padding-right:20px;"|Meldte afbud
|-
| '''10'''
| 66
| style="text-align:left; padding-left:5px; padding-right:20px;"|{{flagikon|USA|3:2}} [[Caroline Dolehide]]<br/>{{flagikon|AUS|3:2}} [[Storm Sanders]]
| style="text-align:left; padding-left:7px; padding-right:20px;"|Kvartfinalister
|-
| '''11'''
| 71
| style="text-align:left; padding-left:5px; padding-right:20px;"|{{flagikon|USA|3:2}} [[Cori Gauff]]<br/>{{flagikon|USA|3:2}} [[Catherine McNally]]
| style="text-align:left; padding-left:7px; padding-right:20px;"|Finalister
|-
| '''12'''
| 79
| style="text-align:left; padding-left:5px; padding-right:20px;"|{{flagikon|UKR|3:2}} [[Nadiia Kitjenok]]<br/>{{flagikon|ROU|3:2}} [[Raluca Olaru]]
| style="text-align:left; padding-left:7px; padding-right:20px;"|Tredje runde
|-
| '''13'''
| 81
| style="text-align:left; padding-left:5px; padding-right:20px;"|{{flagikon|USA|3:2}} [[Asia Muhammad]]<br/>{{flagikon|USA|3:2}} [[Jessica Pegula]]
| style="text-align:left; padding-left:7px; padding-right:20px;"|Første runde
|-
| '''14'''
| 82
| style="text-align:left; padding-left:5px; padding-right:20px;"|{{flagikon|AUS|3:2}} [[Samantha Stosur]]<br/>{{flagikon|CHN|3:2}} [[Zhang Shuai]]
| style="text-align:left; padding-left:7px; padding-right:20px;"|'''Mestre'''
|-
| '''15'''
| 93
| style="text-align:left; padding-left:5px; padding-right:20px;"|{{flagikon|CZE|3:2}} [[Marie Bouzková]]<br/>{{flagikon|CZE|3:2}} [[Lucie Hradecká]]
| style="text-align:left; padding-left:7px; padding-right:20px;"|Kvartfinalister
|-
| '''16'''
| 94
| style="text-align:left; padding-left:5px; padding-right:20px;"|{{flagikon|AUS|3:2}} [[Ellen Perez]]<br/>{{flagikon|CZE|3:2}} [[Květa Peschke]]
| style="text-align:left; padding-left:7px; padding-right:20px;"|Anden runde
|-
| '''17'''
| 98
| style="text-align:left; padding-left:5px; padding-right:20px;"|{{flagikon|SRB|3:2}} [[Aleksandra Krunić]]<br/>{{flagikon|SRB|3:2}} [[Nina Stojanović]]
| style="text-align:left; padding-left:7px; padding-right:20px;"|Anden runde
|}
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