Ved Golden Globe Awards i 2016 vandt Larson i kategorien Bedste Kvindelige Skuespiller - Drama for sin rolle som ''Joy "Ma" Newsome'' i ''[[Room]]''.<ref>{{cite news |url=http://edition.cnn.com/2016/01/10/entertainment/golden-globes-2016-winners-list-feat/ |title=Golden Globes 2016: The winners list |work=edition.cnn.com |date=11. januar 2016 |accessdate=2016-05-07 }}</ref> For den samme rolle vandt hun også en [[Oscar for bedste kvindelige hovedrolle|Oscaren for bedste kvindelige hovedrolle]] i 2016.<ref>{{cite news |url=http://www.nytimes.com/2016/02/29/movies/oscar-winners.html?_r=0 |title=Oscar Winners 2016: The Complete List |work=nytimes.com |date=28. februar 2016 |accessdate=2016-05-07 }}</ref>
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