I april [[2010]] placerede den amerikanske præsident [[Barack Obama]] al-Awlaki på en liste over personer i [[USA]], som [[CIA]] var bemyndiget til at dræbe. Det "målrettede drab" på en amerikansk statsborger, beskrives sommetider som en attentat ordre, der var uden fortilfælde.<ref>[http://www.aclu.org/national-security/al-aulaqi-v-panetta Al-Aulaqi v. Panetta | American Civil Liberties Union<!-- Bot genereret titel -->]</ref><ref name="washingtonpost2">{{Cite news|url=http://www.washingtonpost.com/wp-dyn/content/article/2010/04/06/AR2010040604121.html|title=Muslim cleric Aulaqi is 1st U.S. citizen on list of those CIA is allowed to kill|last=Miller|first=Greg|newspaper=The Washington Post|date=6. april 2010|access-date=9. april 2010}}</ref><ref name="telegraph">{{Cite news|url=http://www.telegraph.co.uk/news/worldnews/northamerica/usa/barackobama/7564581/Barack-Obama-orders-killing-of-US-cleric-Anwar-al-Awlaki.html|title=Barack Obama orders killing of US cleric Anwar al-Awlaki|first=Tom|last=Leonard|date=7. april 2010|publisher=The Daily Telegraph|access-date=8. april 2010|location=London|archive-url=https://web.archive.org/web/20100411042550/http://www.telegraph.co.uk/news/worldnews/northamerica/usa/barackobama/7564581/Barack-Obama-orders-killing-of-US-cleric-Anwar-al-Awlaki.html|archive-date=11. april 2010|url-status=dead}}</ref><ref name="Perez">{{cite news| url=http://online.wsj.com/article/SB10001424052748703296604576005391675065166.html?mod=googlenews_wsj|newspaper=The Wall Street Journal|first=Evan|last=Perez|title=Judge Dismisses Targeted-Killing Suit|date=8. december 2010}}</ref> Anwar al-Awlaki mentes at have skjult sig i det sydøstlige [[Yemen]] i de sidste år af hans liv.<ref name="www.msnbc.com">[http://www.msnbc.msn.com/id/39962939/ns/world_news-mideastn_africa "Yemen charges U.S.-born cleric with plot to kill foreigners"], Associated Press. November 2, 2010; retrieved November 2, 2010.</ref> al-Awlaki blev dræbt ved et [[UAV og drone|droneangreb]] i Yemen den [[30. september]] [[2011]].<ref name="BBC death">{{cite news|title=Islamist cleric Anwar al-Awlaki 'killed in Yemen'|url=http://www.bbc.co.uk/news/world-middle-east-15121879|publisher=BBC News|access-date=30. september 2011|date=30. september 2011}}</ref> To uger senere blev al-Awlakis 16-årige søn, Abdulrahman al-Aulaqi, en amerikansk statsborger, der blev født i [[Denver]], også dræbt af et droneangreb i Yemen.<ref>Kasinov, Laura, "Fatal Strikes Hit Yemen as Violence Escalates", ''The New York Times'', October 15, 2011 [http://www.nytimes.com/2011/10/16/world/middleeast/yemeni-security-forces-fire-on-protesters-in-sana.html Fatal Airstrikes Hit Yemen as Protest Violence Escalates - NYTimes.com]</ref><ref>Herridge, Catherine, "Obama Administration Pressed for Accountability After Americans Killed in Anti-Terror Airstrikes", Fox News, October 25, 2011 [http://www.foxnews.com/politics/2011/10/25/killing-anwar-al-awlaki-unexpected-precedent-for-obama-administration/#ixzz1br7DKnlM Obama Administration Pressed for Accountability After Americans Killed in Anti-Terror Airstrikes | Fox News]</ref><ref>{{cite news|url=http://www.washingtonpost.com/world/national-security/anwar-al-awlakis-family-speaks-out-against-his-sons-deaths/2011/10/17/gIQA8kFssL_story.html|work=The Washington Post|date=18. oktober 2011 | first=Thomas|last=Erdbrink|title=Anwar al-Awlaki's family speaks out against his son's death in airstrike}}</ref> Nasser al-Aulaqi, far til Anwar, lavede efterfølgende en lydoptagelse hvor han fordømte mordet på sin søn og barnebarn som meningsløse drab.<ref name="articles.cnn.com">{{cite news | url=http://articles.cnn.com/2011-12-08/middleeast/world_meast_yemen-awlaki-father_1_imam-anwar-drone-strike-awlaki?_s=PM:MIDDLEEAST | work=CNN | title=Official: Drone attack kills Al-Awlaki's son in Yemen | date=15. oktober 2011 | access-date=11. oktober 2012 | archive-date=20. december 2011 | archive-url=https://web.archive.org/web/20111220120446/http://articles.cnn.com/2011-12-08/middleeast/world_meast_yemen-awlaki-father_1_imam-anwar-drone-strike-awlaki?_s=PM%3AMIDDLEEAST |url-status=dead }}</ref>
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