Efterhånden som sygdommen skrider frem, kan der fremkomme andre medicinske problemer som [[tandsygdom]]me, [[liggesår]], [[fejlernæring]], [[hygiejne|hygiejniske problemer]] eller [[infektion]]er i [[åndedrætssystem]]et, [[hud]]en eller [[øjne]]ne. Disse problemer kan ofte undgås med nøje håndtering, men professionel behandling er påkrævet hvis først de forekommer.<ref name="pmid10369823">{{vcite journal | vauthors = Gambassi G, Landi F, Lapane KL, Sgadari A, Mor V, Bernabei R | title = Predictors of Mortality in Patients with Alzheimer's Disease Living in Nursing Homes | journal = Journal of Neurology, Neurosurgery, and Psychiatry | volume = 67 | issue = 1 | pages = 59–65 | year = 1999 | pmid = 10369823 | pmc = 1736445 | doi = 10.1136/jnnp.67.1.59 | month = July }}</ref><ref>Medicinske problemer:
* {{vcite journal | author = Head B | title = Palliative Care for Persons with Dementia | journal = Home Healthcare Nurse | volume = 21 | issue = 1 | pages = 53–60; quiz 61 | year = 2003 | pmid = 12544465 | doi = 10.1097/00004045-200301000-00012 | month = January }}
* {{vcite journal | vauthors = Friedlander AH, Norman DC, Mahler ME, Norman KM, Yagiela JA | title = Alzheimer's Disease: Psychopathology, Medical Management and Dental Implications | journal = Journal of the American Dental Association | volume = 137 | issue = 9 | pages = 1240–51 | year = 2006 | pmid = 16946428 | month = September }}
* {{vcite journal | author = Belmin J | title = Practical Guidelines for the Diagnosis and Management of Weight Loss in Alzheimer's Disease: A Consensus from Appropriateness Ratings of a Large Expert Panel | journal = The Journal of Nutrition, Health & Aging | volume = 11 | issue = 1 | pages = 33–7 | year = 2007 | pmid = 17315078 }}
* {{vcite journal | vauthors = McCurry SM, Gibbons LE, Logsdon RG, Vitiello M, Teri L | title = Training Caregivers to Change the Sleep Hygiene Practices of Patients with Dementia: The NITE-AD Project | journal = Journal of the American Geriatrics Society | volume = 51 | issue = 10 | pages = 1455–60 | year = 2003 | pmid = 14511168 | doi = 10.1046/j.1532-5415.2003.51466.x | month = October }}
* {{vcite journal | vauthors = Perls TT, Herget M | title = Higher Respiratory Infection Rates on an Alzheimer's Special Care Unit and successful intervention | journal = Journal of the American Geriatrics Society | volume = 43 | issue = 12 | pages = 1341–4 | year = 1995 | pmid = 7490383 | month = December | doi=10.1111/j.1532-5415.1995.tb06611.x}}</ref> I løbet af sygdommens sidste stadier koncentreres behandlingen om at lette ubehag frem til døden indtræffer, ofte med hjælp fra et [[hospice]].<ref name="pmid12854952">{{vcite journal | vauthors = Shega JW, Levin A, Hougham GW |display-authors=etal | title = Palliative Excellence in Alzheimer Care Efforts (PEACE): A Program Description | journal = Journal of Palliative Medicine | volume = 6 | issue = 2 | pages = 315–20 | year = 2003 | pmid = 12854952 | doi = 10.1089/109662103764978641 }}</ref>
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