Periodisk faste har lignende effekter som [[kaloriebegrænsing|kaloriebegrænset kost]],<ref name="AHA2017" /> og er blevet studeret i 2000-tallet som en måde at reducere kost-relaterede sygdomme som [[metabolt syndrom]].<ref name=NEJM2019/><ref name="AHA2017" /><ref name="Cioffi2018">{{cite journal | vauthors = Cioffi I, Evangelista A, Ponzo V, Ciccone G, Soldati L, Santarpia L, Contaldo F, Pasanisi F, Ghigo E, Bo S | display-authors = 6 | title = Intermittent versus continuous energy restriction on weight loss and cardiometabolic outcomes: a systematic review and meta-analysis of randomized controlled trials | journal = Journal of Translational Medicine | volume = 16 | issue = 1 | pages = 371 | date = december 2018 | pmid = 30583725 | pmc = 6304782 | doi = 10.1186/s12967-018-1748-4 | type = Systematic review }}</ref><ref name="Sainsbury2018">{{cite journal | vauthors = Sainsbury A, Wood RE, Seimon RV, Hills AP, King NA, Gibson AA, Byrne NM | title = Rationale for novel intermittent dieting strategies to attenuate adaptive responses to energy restriction | journal = Obesity Reviews | volume = 19 | issue = Suppl 1 | pages = 47–60 | date = december 2018 | pmid = 30511512 | doi = 10.1111/obr.12787 | s2cid = 54552826 }}</ref><ref name="harris">{{cite journal | vauthors = Harris L, Hamilton S, Azevedo LB, Olajide J, De Brún C, Waller G, Whittaker V, Sharp T, Lean M, Hankey C, Ells L | display-authors = 6 | title = Intermittent fasting interventions for treatment of overweight and obesity in adults: a systematic review and meta-analysis | journal = JBI Database of Systematic Reviews and Implementation Reports | volume = 16 | issue = 2 | pages = 507–547 | date = februar 2018 | pmid = 29419624 | doi = 10.11124/JBISRIR-2016-003248 | url = https://research.tees.ac.uk/ws/files/6438175/621636.pdf | access-date = 23. oktober 2019 | url-status = live | s2cid = 46780578 | archive-url = https://web.archive.org/web/20191030172956/https://research.tees.ac.uk/ws/files/6438175/621636.pdf | archive-date = 30. oktober 2019 }}</ref>
Ifølge [[American Heart Association]] kan periodisk faste give [[vægttab]], reducere [[insulinresistens]] og mindske risikoen for cardiometabolske sygdomme, selvom langsigtede effekter ikke er kendt.<ref name="AHA2017" /> Et studie fra 2019 konkluderede at periodisk faste kan hjælpe med [[overvægt]], insulinresistens, [[dyslipidæmi]], [[hypertension]] og [[betændelse]].<ref name=NEJM2019/> Et studie fra 202 indikerede at periodisk faste generelt ikke er farligt.<ref name=":6">{{{cite journal |vauthors=Varady KA, Cienfuegos S, Ezpeleta M, Gabel K |title=Clinical application of intermittent fasting for weight loss: progress and future directions |journal=Nat Rev Endocrinol |volume= |issue= |pages= |date=februar 2022 |pmid=35194176 |doi=10.1038/s41574-022-00638-x |url=}}</ref>
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