I sin første kamp efter at hans karantæne var blevet ophævet mødte Silva [[Michael Bisping]] den [[27. februar]] [[2016]], på [[UFC Fight Night 84]].<ref>{{cite web|url=http://espn.go.com/mma/story/_/id/14433836/middleweights-anderson-silva-michael-bisping-headline-ufc-event-london-feb-27|title=Anderson Silva, Michael Bisping to headline UFC event in London|author=Brett Okamoto|publisher=espn.go.com|date=2015-12-25|access-date=2015-12-25|archive-date=24. marts 2016|archive-url=https://web.archive.org/web/20160324142725/http://espn.go.com/mma/story/_/id/14433836/middleweights-anderson-silva-michael-bisping-headline-ufc-event-london-feb-27|url-status=live}}</ref> Han tabte kampen via [[enstemmig afgørelse]]. Men kampen var yderst kontroversiel da Silva i slutningen af 3. omgang slog Bisping ned med et flyvende knæ mens Bisping signalerede til dommer [[Herb Dean]] at han havde mistet sin tandbeskytter. Silva troede at han havde vundet kampen og begyndte at fejre det mens Dean sagde at kampen ikke var ovre og den fortsatte i yderligere 2 omgange og gik tiden ud.<ref>{{cite web|url=http://mmajunkie.com/2016/02/ufc-fight-night-84-results-michael-bisping-tops-anderson-silva-in-crazy-bloody-war|title=UFC Fight Night 84 results: Michael Bisping tops Anderson Silva in crazy, bloody war|publisher=mmajunkie.com|author=Steven Marrocco|date=27. februar 2016|access-date=27. februar 2016|archive-date=28. februar 2016|archive-url=https://web.archive.org/web/20160228101125/http://mmajunkie.com/2016/02/ufc-fight-night-84-results-michael-bisping-tops-anderson-silva-in-crazy-bloody-war|url-status=live}}</ref> Both participants were awarded ''Fight of the Night'' honors.<ref>{{cite web|url=http://www.sherdog.com/news/news/UFC-Fight-Night-London-Bonuses-Bisping-Silva-Askham-Packalen-Earn-3650K-100945|title=UFC Fight Night London Bonuses: Bisping, Silva, Askham, Packalen earn $50K|publisher=sherdog.com|author=Tristen Critchfield|date=27. februar 2016|access-date=27. februar 2016|archive-date=29. februar 2016|archive-url=https://web.archive.org/web/20160229094620/http://www.sherdog.com/news/news/UFC-Fight-Night-London-Bonuses-Bisping-Silva-Askham-Packalen-Earn-3650K-100945|url-status=live}}</ref>
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