{| class="wikitable" style="margin-left:1em; text-align:center;"
! style="width:70px;"|Seedning
! style="width:60px;"|Rang.<ref name="wta20220516">Rangering på [[WTA's verdensrangliste]] pr. [[16. maj]] [[2022]].</ref>
! Spiller
! Resultat
|-
| '''1'''
| 1
| style="text-align:left; padding-left:5px; padding-right:20px;"|{{flagikon|POL|3:2}} [[Iga Świątek]]
| style="text-align:left; padding-left:7px; padding-right:20px; background-color:{{Tennisfarve|V}};"|'''Mester'''
|-
| '''2'''
| 2
| style="text-align:left; padding-left:5px; padding-right:20px;"|{{flagikon|CZE|3:2}} [[Barbora Krejčíková]]
| style="text-align:left; padding-left:7px; padding-right:20px; background-color:{{Tennisfarve|1/64}};"|Første runde
|-
| '''3'''
| 3
| style="text-align:left; padding-left:5px; padding-right:20px;"|{{flagikon|ESP|3:2}} [[Paula Badosa]]
| style="text-align:left; padding-left:7px; padding-right:20px; background-color:{{Tennisfarve|1/16}};"|Tredje runde
|-
| '''4'''
| 4
| style="text-align:left; padding-left:5px; padding-right:20px;"|{{flagikon|GRE|3:2}} [[Maria Sakkari]]
| style="text-align:left; padding-left:7px; padding-right:20px; background-color:{{Tennisfarve|1/32}};"|Anden runde
|-
| '''5'''
| 5
| style="text-align:left; padding-left:5px; padding-right:20px;"|{{flagikon|EST|3:2}} [[Anett Kontaveit]]
| style="text-align:left; padding-left:7px; padding-right:20px; background-color:{{Tennisfarve|1/64}};"|Første runde
|-
| '''6'''
| 6
| style="text-align:left; padding-left:5px; padding-right:20px;"|{{flagikon|TUN|3:2}} [[Ons Jabeur]]
| style="text-align:left; padding-left:7px; padding-right:20px; background-color:{{Tennisfarve|1/64}};"|Første runde
|-
| '''7'''
| 7
| style="text-align:left; padding-left:5px; padding-right:20px;"|{{noflag|size=20px}} [[Aryna Sabalenka]]
| style="text-align:left; padding-left:7px; padding-right:20px; background-color:{{Tennisfarve|1/16}};"|Tredje runde
|-
| '''8'''
| 8
| style="text-align:left; padding-left:5px; padding-right:20px;"|{{flagikon|CZE|3:2}} [[Karolína Plíšková]]
| style="text-align:left; padding-left:7px; padding-right:20px; background-color:{{Tennisfarve|1/32}};"|Anden runde
|-
| '''9'''
| 9
| style="text-align:left; padding-left:5px; padding-right:20px;"|{{flagikon|USA|3:2}} [[Danielle Collins]]
| style="text-align:left; padding-left:7px; padding-right:20px; background-color:{{Tennisfarve|1/32}};"|Anden runde
|-
| '''10'''
| 10
| style="text-align:left; padding-left:5px; padding-right:20px;"|{{flagikon|ESP|3:2}} [[Garbiñe Muguruza]]
| style="text-align:left; padding-left:7px; padding-right:20px; background-color:{{Tennisfarve|1/64}};"|Første runde
|-
| '''11'''
| 11
| style="text-align:left; padding-left:5px; padding-right:20px;"|{{flagikon|USA|3:2}} [[Jessica Pegula]]
| style="text-align:left; padding-left:7px; padding-right:20px; background-color:{{Tennisfarve|1/4}};"|Kvartfinalist
|-
| '''12'''
| 12
| style="text-align:left; padding-left:5px; padding-right:20px;"|{{flagikon|GBR|3:2}} [[Emma Raducanu]]
| style="text-align:left; padding-left:7px; padding-right:20px; background-color:{{Tennisfarve|1/32}};"|Anden runde
|-
| '''13'''
| 13
| style="text-align:left; padding-left:5px; padding-right:20px;"|{{flagikon|LAT|3:2}} [[Jeļena Ostapenko]]
| style="text-align:left; padding-left:7px; padding-right:20px; background-color:{{Tennisfarve|1/32}};"|Anden runde
|-
| '''14'''
| 14
| style="text-align:left; padding-left:5px; padding-right:20px;"|{{flagikon|SUI|3:2}} [[Belinda Bencic]]
| style="text-align:left; padding-left:7px; padding-right:20px; background-color:{{Tennisfarve|1/16}};"|Tredje runde
|-
| '''15'''
| 15
| style="text-align:left; padding-left:5px; padding-right:20px;"|{{noflag|size=20px}} [[Viktorija Azarenka]]
| style="text-align:left; padding-left:7px; padding-right:20px; background-color:{{Tennisfarve|1/16}};"|Tredje runde
|-
| '''16'''
| 16
| style="text-align:left; padding-left:5px; padding-right:20px;"|{{flagikon|KAZ|3:2}} [[Jelena Rybakina]]
| style="text-align:left; padding-left:7px; padding-right:20px; background-color:{{Tennisfarve|1/16}};"|Tredje runde
|-
| '''17'''
| 17
| style="text-align:left; padding-left:5px; padding-right:20px;"|{{flagikon|CAN|3:2}} [[Leylah Fernandez]]
| style="text-align:left; padding-left:7px; padding-right:20px; background-color:{{Tennisfarve|1/4}};"|Kvartfinalist
|-
| '''18'''
| 18
| style="text-align:left; padding-left:5px; padding-right:20px;"|{{flagikon|USA|3:2}} [[Cori Gauff]]
| style="text-align:left; padding-left:7px; padding-right:20px; background-color:{{Tennisfarve|F}};"|Finalist
|-
| '''19'''
| 19
| style="text-align:left; padding-left:5px; padding-right:20px;"|{{flagikon|ROU|3:2}} [[Simona Halep]]
| style="text-align:left; padding-left:7px; padding-right:20px; background-color:{{Tennisfarve|1/32}};"|Anden runde
|-
| '''20'''
| 20
| style="text-align:left; padding-left:5px; padding-right:20px;"|{{noflag|size=20px}} [[Darja Kasatkina]]
| style="text-align:left; padding-left:7px; padding-right:20px; background-color:{{Tennisfarve|1/2}};"|Semifinalist
|-
| '''21'''
| 22
| style="text-align:left; padding-left:5px; padding-right:20px;"|{{flagikon|GER|3:2}} [[Angelique Kerber]]
| style="text-align:left; padding-left:7px; padding-right:20px; background-color:{{Tennisfarve|1/16}};"|Tredje runde
|-
| '''22'''
| 23
| style="text-align:left; padding-left:5px; padding-right:20px;"|{{flagikon|USA|3:2}} [[Madison Keys]]
| style="text-align:left; padding-left:7px; padding-right:20px; background-color:{{Tennisfarve|1/8}};"|Fjerde runde
|-
| '''23'''
| 24
| style="text-align:left; padding-left:5px; padding-right:20px;"|{{flagikon|SUI|3:2}} [[Jil Teichmann]]
| style="text-align:left; padding-left:7px; padding-right:20px; background-color:{{Tennisfarve|1/8}};"|Fjerde runde
|-
| '''24'''
| 25
| style="text-align:left; padding-left:5px; padding-right:20px;"|{{flagikon|SLO|3:2}} [[Tamara Zidanšek]]
| style="text-align:left; padding-left:7px; padding-right:20px; background-color:{{Tennisfarve|1/16}};"|Tredje runde
|-
| '''25'''
| 26
| style="text-align:left; padding-left:5px; padding-right:20px;"|{{noflag|size=20px}} [[Ljudmila Samsonova]]
| style="text-align:left; padding-left:7px; padding-right:20px; background-color:{{Tennisfarve|1/64}};"|Første runde
|-
| '''26'''
| 27
| style="text-align:left; padding-left:5px; padding-right:20px;"|{{flagikon|ROU|3:2}} [[Sorana Cîrstea]]
| style="text-align:left; padding-left:7px; padding-right:20px; background-color:{{Tennisfarve|1/32}};"|Anden runde
|-
| '''27'''
| 28
| style="text-align:left; padding-left:5px; padding-right:20px;"|{{flagikon|USA|3:2}} [[Amanda Anisimova]]
| style="text-align:left; padding-left:7px; padding-right:20px; background-color:{{Tennisfarve|1/8}};"|Fjerde runde
|-
| '''28'''
| 29
| style="text-align:left; padding-left:5px; padding-right:20px;"|{{flagikon|ITA|3:2}} [[Camila Giorgi]]
| style="text-align:left; padding-left:7px; padding-right:20px; background-color:{{Tennisfarve|1/8}};"|Fjerde runde
|-
| '''29'''
| 30
| style="text-align:left; padding-left:5px; padding-right:20px;"|{{noflag|size=20px}} [[Veronika Kudermetova]]
| style="text-align:left; padding-left:7px; padding-right:20px; background-color:{{Tennisfarve|1/4}};"|Kvartfinalist
|-
| '''30'''
| 31
| style="text-align:left; padding-left:5px; padding-right:20px;"|{{noflag|size=20px}} [[Jekaterina Aleksandrova]]
| style="text-align:left; padding-left:7px; padding-right:20px; background-color:{{Tennisfarve|1/32}};"|Anden runde
|-
| '''31'''
| 33
| style="text-align:left; padding-left:5px; padding-right:20px;"|{{flagikon|BEL|3:2}} [[Elise Mertens]]
| style="text-align:left; padding-left:7px; padding-right:20px; background-color:{{Tennisfarve|1/8}};"|Fjerde runde
|-
| '''32'''
| 34
| style="text-align:left; padding-left:5px; padding-right:20px;"|{{flagikon|CZE|3:2}} [[Petra Kvitová]]
| style="text-align:left; padding-left:7px; padding-right:20px; background-color:{{Tennisfarve|1/32}};"|Anden runde
|}
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