{{Infoboks_tennisturnering
| titel                 = US Open 2021
| billede               = 
| billedtekst           = 
| pixels                = 
| alt                   = 
| arrangør              = [[United States Tennis Association]]
| turneringsnummer      = 141
| dato                  = [[30. august]] - [[12. september]] [[2021]]<br/>Kvalifikation: [[24. august|24.]] - [[27. august]] [[2021]]
| spillested            = [[USTA Billie Jean King National Tennis Center]]
| værtsby               = [[New York City]], [[USA]]
| underlag              = [[Hardcourt]] (Laykold)
| kategori              = [[Grand slam]]
| præmiesum             = [[Amerikansk dollar|$]] 57.462.000 (inkl. [[per diem]])<ref name="prizes">[https://www.usopen.org/en_US/visit/prize_money.html US Open - ''2021 US Open Prize Money''] {{en sprog}}</ref>
| herresingle           = {{flagikon|RUS|3:2|size=18px}} [[Daniil Medvedev]]
| herresingle_titel_nr  = 1
| damesingle            = {{flagikon|GBR|3:2|size=18px}} [[Emma Raducanu]]
| damesingle_titel_nr   = 1
| herredouble           = {{flagikon|USA|3:2|size=18px}} [[Rajeev Ram]]<br/>{{flagikon|GBR|3:2|size=18px}} [[Joe Salisbury]]
| herredouble_titel_nr  = 1
| damedouble            = {{flagikon|AUS|3:2|size=18px}} [[Samantha Stosur]]<br/>{{flagikon|CHN|3:2|size=18px}} [[Zhang Shuai]]
| damedouble_titel_nr   = 1
| mixeddouble           = {{flagikon|USA|3:2|size=18px}} [[Desirae Krawczyk]]<br/>{{flagikon|GBR|3:2|size=18px}} [[Joe Salisbury]]
| mixeddouble_titel_nr  = 1
| antal_tilskuere       = 631.134<ref>[https://www.espn.com/tennis/story/_/id/32201972/the-new-era-tennis-here-daniil-medvedev-real-other-takeaways-wild-us-open ESPN - ''The new era of tennis is here, Daniil Medvedev is for real and other takeaways from a wild US Open'' (13. september 2021)] {{en sprog}}</ref>
| forrige               = [[US Open 2020|2020]]
| næste                 = [[US Open 2022|2022]]
}}
'''US Open 2021''' var en [[tennis]]turnering, der blev spillet udendørs på [[hardcourt]]-baner i perioden [[30. august]] - [[12. september]] [[2021]] i [[USTA Billie Jean King National Tennis Center]] i [[New York City]], [[USA]]. Det var den 141. udgave af [[US Open (tennis)|mesterskabet]] og den fjerde og sidste [[Grand Slam (tennis)|grand slam]]-turnering i [[2021]]. Kvalifikationen i singlerækkerne spilledes samme sted den [[24. august|24.]] - [[27. august]] [[2021]].
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