Reyes mødte Matt Frevola den 14. januar 2018 på [[UFC Fight Night: Stephens vs. Choi|UFC Fight Night: Stephens vs.]] [[UFC Fight Night: Stephens vs. Choi|Choi]]. <ref>{{Cite web|url=http://mmadna.nl/marco-polo-reyes-vecht-tegen-matt-frevola-tijdens-ufc-st-louis/|title=Marco Polo Reyes vecht tegen Matt Frevola tijdens UFC St.Louis|last=DNA|first=MMA|website=mmadna.nl|language=en-US|access-date=2017-11-08}}</ref> Han vandt via knockout et minut inde i kampen. <ref>{{Kilde nyheder|url=https://www.mmamania.com/2018/1/14/16891616/ufc-knockout-watch-marco-polo-reyes-destroy-matt-frevola-with-one-punch-in-wild-fight-mma|title=Knockout! Watch Reyes Sleep Frevola In Wild Barn Burner|work=MMAmania.com|access-date=2018-01-15}}</ref> Han blev tildelt ''Performance of the Night-bonusprisen'' . <ref name="Tristen Critchfield">{{Cite web|url=http://www.sherdog.com/news/news/UFC-Fight-Night-124-Bonuses-Stephens-Choi-Elkins-Reyes-Receive-3650K-Checks-131121|title=UFC Fight Night 124 bonuses: Stephens, Choi, Elkins, Reyes receive $50K checks|last=Tristen Critchfield|date=2018-01-14|publisher=sherdog.com|access-date=2018-01-14}}</ref>
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