{| class="wikitable" style="margin-left:1em; text-align:center;"
! style="width:60px;"|Rang.<ref name="atp20230522"/>
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| style="text-align:left; padding-left:5px; padding-right:20px;"|{{flagikon|ESP|3:2}} [[Rafael Nadal]]
| style="text-align:left; padding-left:7px; padding-right:20px;"|[[Hofte]]skade<ref>[https://www.nytimes.com/2023/05/18/sports/tennis/nadal-withdraws-french-open.html The New York Times - ''Rafael Nadal Withdraws From the French Open, Wants to Play One More Year'' (18. maj 2023)] {{en sprog}}</ref>
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| 20
| style="text-align:left; padding-left:5px; padding-right:20px;"|{{flagikon|ITA|3:2}} [[Matteo Berrettini]]
| style="text-align:left; padding-left:7px; padding-right:20px;"|[[Mave]][[muskel]]skade<ref>[https://tennis-infinity.com/atp/injured-matteo-berrettini-withdraws-from-2023-roland-garros Tennis Infinity - ''Injured Matteo Berrettini Withdraws From 2023 Roland Garros'' (20. maj 2023)] {{en sprog}}</ref>
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| 21
| style="text-align:left; padding-left:5px; padding-right:20px;"|{{flagikon|ESP|3:2}} [[Pablo Carreño Busta]]
| style="text-align:left; padding-left:7px; padding-right:20px;"|Ikke oplyst<ref>[https://www.thefirstserve.com.au/post/french-open-injuries-and-withdrawls The First Serve - ''FRENCH OPEN INJURIES AND WITHDRAWLS'' (27. maj 2023)] {{en sprog}}</ref>
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| 22
| style="text-align:left; padding-left:5px; padding-right:20px;"|{{flagikon|CRO|3:2}} [[Marin Čilić]]
| style="text-align:left; padding-left:7px; padding-right:20px;"|[[Knæ]]skade<ref>[https://www.tennisworldusa.org/tennis/news/Rafael_Nadal/132905/marin-cilic-joins-rafael-nadal-nick-kyrgios-in-withdrawing-from-french-open/ Tennis World - ''Marin Cilic joins Rafael Nadal, Nick Kyrgios in withdrawing from French Open'' (20. maj 2023)] {{en sprog}}</ref>
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| 25
| style="text-align:left; padding-left:5px; padding-right:20px;"|{{flagikon|AUS|3:2}} [[Nick Kyrgios]]
| style="text-align:left; padding-left:7px; padding-right:20px;"|[[Fod (anatomi)|Fod]]skade<ref>[https://www.cbssports.com/tennis/news/french-open-2023-nick-kyrgios-to-miss-roland-garros-due-to-injury-suffered-during-robbery/ CBS Sport - ''French Open 2023: Nick Kyrgios to miss Roland Garros due to injury suffered during robbery'' (18. maj 2023)] {{en sprog}}</ref>
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