Newsom har en bachelorgrad i statskundskab fra [[Santa Clara University]].<ref name="Port"/><ref name="Santa">{{cite news |url=http://media.www.thesantaclara.com/media/storage/paper946/news/2008/02/14/News/San-Franciscos.Gavin.Newsom.Sits.Down.With.The.Santa.Clara-3210314.shtml |title=San Francisco's Gavin Newsom sits down with The Santa Clara Newsom discusses how Santa Clara guides his career |last=Boffi|first=Kristen |date=12. april 2008 |work=The Santa Clara |access-date=26. august 2021 |archive-url=https://web.archive.org/web/20090426073753/http://media.www.thesantaclara.com/media/storage/paper946/news/2008/02/14/News/San-Franciscos.Gavin.Newsom.Sits.Down.With.The.Santa.Clara-3210314.shtml|archive-date=26. april 2009|url-status=dead}}</ref> I 1992 startede han en vinhandel som siden er vokset til en kæde med adskillige forretninger inkl. vingårde, restauranter og hoteler.<ref>{{Kilde www | url=https://www.plumpjack.com/history | titel=plumpjack, a history |udgiver=PlumpJack Group | hentet=26. august 2021}}</ref>
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