Love om obligatorisk vaccination er blevet foreslået til lovgivningen, inklusive [[California Senate Bill 277]] i USA og [[No Jab No Pay]] i [[Australien]], og vaccineskeptikere har været kraftigt imod dette.<ref>{{Cite news |url=http://discovermagazine.com/2018/dec/fostering-fear |title=The Long History of America's Anti-Vaccination Movement |access-date=2019-02-02 |website=DiscoverMagazine.com}}</ref><ref>{{Cite news |url=https://www.politico.eu/article/how-anti-vax-went-viral/ |title=How anti-vax went viral |last=Young |first=Zachary |date=2018-11-21 |access-date=2019-02-02 |name-list-style=vanc}}</ref><ref>{{Cite news |url=https://www.independent.co.uk/news/world/europe/anti-vaxxers-italy-vaccine-measles-epidemic-europe-us-vaccination-global-health-security-agenda-a8560021.html |title=How the anti-vaxxers are winning in Italy |date=2018-09-28 |access-date=2019-02-02 |language=en}}</ref> Modstand mod obligatorisk vaccination kan være baseret på vaccineskepsis, bekymringer om rettigheder eller reducere offentlig tillid til vaccinationer eller mistro til medicinalindustrien.<ref name="wolfesharp" /><ref>{{Cite web |url=https://www.mystatesman.com/news/state--regional-govt--politics/civil-liberties-center-vaccination-debate-texas/lWzq91qhSyAKcY8MiaWnYM/ |title='Civil liberties' at center of vaccination debate in Texas |last=Chang |first=Julie |date=12. juli 2017 |website=Mystatesman |publisher=[[Austin American-Statesman]] |name-list-style=vanc |access-date=11. august 2020 |archive-date=13. juli 2017 |archive-url=https://web.archive.org/web/20170713075809/https://www.mystatesman.com/news/state--regional-govt--politics/civil-liberties-center-vaccination-debate-texas/lWzq91qhSyAKcY8MiaWnYM/ |url-status=dead }}</ref><ref>{{Cite web |url=https://www.nytimes.com/roomfordebate/2014/03/23/making-vaccination-mandatory-for-all-children/in-britain-vaccinate-with-persuasion-not-coercion |title=In Britain, Vaccinate With Persuasion, not Coercion |last=Elliman |first=David |last2=Bedford |first2=Helen |date=23. marts 2014 |website=The New York Times |name-list-style=vanc}}</ref><ref>{{Cite news |url=https://health.spectator.co.uk/anti-vaxxers-have-embraced-social-media-were-paying-for-fake-news-with-real-lives/ |title=Anti-vaxxers have embraced social media. We're paying for fake news with real lives |date=2017-06-28 |access-date=2019-02-02 |language=en-GB |archive-date= 5. april 2019 |archive-url=https://web.archive.org/web/20190405124330/https://health.spectator.co.uk/anti-vaxxers-have-embraced-social-media-were-paying-for-fake-news-with-real-lives/ |url-status=dead }}</ref><ref>Bourree Lam, [https://www.theatlantic.com/business/archive/2015/02/vaccines-are-profitable-so-what/385214/ Vaccines Are Profitable, So What?]. ''The Atlantic'' Feb. 10, 2015</ref> National Vaccine Information Center (USA) er den mest indflydelsesrige organisation mod vaccination<ref>[https://www.sciencenews.org/article/vaccine-hesitancy-history-damage-anti-vaccination Vaccine hesitancy is nothing new. Here’s the damage it’s done over centuries. Science News 2021]</ref>.
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