Hun blev nomineret i henholdsvis 1987 og 1989 til en [[Oscar for bedste kvindelige hovedrolle]] for ''[[Alien (film)|Alien]]'' og ''[[Gorillaer i disen]]''.<ref>{{cite web |title=The 59th Academy Awards <nowiki>|</nowiki> 1987 - Actress in a Leading Role |url=https://www.oscars.org/oscars/ceremonies/1987 |publisher=oscars.org |accessdate={{date|2019-08-01}}}}</ref><ref name="Oscar1989">{{cite web |title=The 61st Academy Awards <nowiki>|</nowiki> 1989|url=https://www.oscars.org/oscars/ceremonies/1989 |publisher=oscars.org |accessdate={{date|2019-08-01}}}}</ref> Desuden for [[Oscar for bedste kvindelige birolle|bedste kvindelige birolle]] i 1989 for ''[[Working Girl]]''.<ref name="Oscar1989" />
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