Denne terminologi er kontroversiel. En forsker i infektiøse sygdomme Kristian Andersen<ref group=note>[https://www.scripps.edu/faculty/andersen Kristian G. Andersen, PhD], 'Department of Immunology and Microbiology' ved ''Scripps Research'', Scripps.edu </ref> fortalte radiostationen "National Public Radio" (NPR), at "SARS-CoV-2 muterer hele tiden. Der er mange dobbeltmutationer overalt. Varianten i Indien bør ikke beskrives som sådan."<ref>{{cite news |title=People Are Talking About A 'Double Mutant' Variant In India. What Does That Mean? |url=https://www.npr.org/sections/goatsandsoda/2021/04/24/988744811/people-are-talking-about-a-double-mutant-variant-in-india-what-does-that-mean |access-date=27. april 2021 |work=NPR.org |language=en}}</ref>
Historie Vira