{| class="wikitable sortable" style="text-align:center"
! Rank
! Spiller
! Klub
! Mål<ref>[http://history.eurohandball.com/ec/cl/women/2020-21/scorers Goalscorers]</ref>
|-
|1
|align="left"|{{flagicon|SLO}} [[Ana Gros]]
|align="left"|{{flagicon|FRA}} [[Brest Bretagne Handball]]
|135
|-
|2
|align="left"|{{flagicon|ROU}} [[Cristina Neagu]]
|align="left"|{{flagicon|ROU}} [[CSM București (kvindehåndbold)|CSM Bucureşti]]
|115
|-
|3
|align="left"|{{flagicon|NOR}} [[Veronica Kristiansen]] 
|align="left"|{{flagicon|HUN}} [[Győri Audi ETO KC]]
|97
|-
|4
|align="left"|{{flagicon|MNE}} [[Jovanka Radičević]] 
|align="left"|{{flagicon|MNE}} [[ŽRK Budućnost Podgorica|ŽRK Budućnost]]
|94
|-
|rowspan=2|5
|align="left"|{{flagicon|CRO}} [[Dejana Milosavljević]]
|align="left"|{{flagicon|CRO}} [[RK Podravka Koprivnica]]
|rowspan=2|88
|-
|align="left"|{{flagicon|NOR}} [[Henny Reistad]]
|align="left"|{{flagicon|NOR}} [[Vipers Kristiansand]]
|-
|7
|align="left"|{{flagicon|NOR}} [[Stine Bredal Oftedal]]
|align="left"|{{flagicon|HUN}} [[Győri Audi ETO KC]]
|87
|-
|rowspan=2|8
|align="left"|{{flagicon|NED}} [[Lois Abbingh]]
|align="left"|{{flagicon|DEN}} [[Odense Håndbold]]
|rowspan=2|84
|-
|align="left"|{{flagicon|FRA}} [[Estelle Nze Minko]]
|align="left"|{{flagicon|HUN}} [[Győri Audi ETO KC]]
|-
|10
|align="left"|{{flagicon|DEN}} [[Mette Tranborg]]
|align="left"|{{flagicon|DEN}} [[Team Esbjerg]]
|77
|}
Sport Kultur