What causes high blood sugar level despite taking Metformin while having acute pancreatitis?
Patient: Hello, I am a male 58 years old. I had acute pancretitis in 2014 so since then I have been on metformin and glimepride but the last moth and a half it has been hihg from 200 to 400. What may be causing the change it was under control and diet has not changed. I see my Dr tomorrow but just want to hear from you. Doctor: Hello and Welcome to ‘Ask A Doctor’ service.  I have reviewed your query and here is my advice.  Pancreatitis can damage the insulin producing cells of your pancreas and leads to a state of low insulin and may leads to diabetes. In that case you may require insulin injections to optimize the blood sugar level.  Do a fasting blood sugar level and start insulin accordingly. Wishing you good health.