Has periodic spells of skin sores, come as blisters, itch badly. What could be the cause ?
Patient: My brother-in-law has perioditic spells of skin sores. They come on as a blister and change to a quarter size-3 inch sore overnight. They itch insanely and stay for awhile then go away. He feels bad physically beside the discomfort. Has been to 10 dr and noone has an answer. His health is deteriorating. What could be the cause?  I should have known this is not what it seems to be. Just forget it, he is going to more doctors himself. Doctor: Hello i think it is pemphigus vulgaris it is autoimmune blistering disorder.it causes itching which causes recurrent blisters.it can be cured by oral antihistamine.antibiotic.steriods and application of gentian violet on the blisters and lobate gn ointment on the sores.if not subsided or recurrences are more go for dexamethasone pulse therapy which consists of  dexamethazone inj about 12 vials for 3 continous days along with cyclophospamide monthly once for one year