Could the extreme fatigue, depression and lethargy caused due to the overtaking of Methylprednisolone?
Patient: I think my wife is accidentally overtaking Methylprednisolone (medrol). Her prescript is for 1 ½ 4 mg. tabs per day. I think she s been taking 6 tabs per day. She is extremely fatigued, depressed, and just has zero energy and is lethargic. Could this be from overtaking the methylprednisolone ????? Doctor: HiThanks for using healthcare magicCorticosteroids also lead to depression. In her case, if she has been taking them for last many years, depression could be due to this. Better to consult a physician for decrease the dose of it. Decreasing corticosteroid would help to decrease the underline depression.Thanks