What causes leg/back pain when having high RBC/RDW and low MCV/MCH?
Patient: Hi, my 7 year old daughter has high RBC and RDW but low MCV and MCH. Her hemoglobin is good at 11.5. We are of African decent. She does complain of leg and back pain often. Should I be worried about sickle cell disease or thalasemia? or even a blood cancer? the pediatrician said she has hemoglobinopathy but is doing further testing to find out what exactly. Doctor: High rbc with low mcv is seen in beta thallasemia minor commonly.  So just go for hb chromatography.  It will give exact dignosis of hemoglobinopathies. If ur hbA2 level is above 3.5 then its thallasemia minor. so go for hb chromatography.