Suffered stroke, seizures. Taking eptoin, stopped it due to allergy, taking wysolone. Safe to take?
Patient: hello doctor, my mother had a stroke last feb n later few months ago she had a seizure and strtd using eptoin .later cz of allergy doctors stopped dat and instead gave levipil plus wysolone for allergy.. today again she s havin skin allergy a little bit as earlier...so should she take wysolone now?? doctor hd asked her 2 decreas the dose n she was nw takin half a pill wysolone alternativly. so if she take a tablet today will dat be okay?/??? plzzz plz do reply. Doctor: Hello, I am not sure what 'allergic reaction' your mother to the eptoin (phenytoin) requiring the drug to be stopped and starting prednisolone for the rash. Phenytoin can cause a severe drug induced systemic reaction called Drug rash, Eosinophilia, Systemic Symptoms (DRESS for short) where there is fever, big glands, skin peeling off and liver problems. Other drugs implicated in DRESS should ten be avoided. I am certain your mother did not have this...but maybe just a rash that can be itchy and known as urticaria. Prednisolone is occasionally used a last resort but antihistamines are more than effective in treating urticaria. The alternative antiepileptic is a good choice, and suggest you discuss with your Neurologist in tapering and stopping the steroids after 5 days if the diagnosis was not DRESS.  I hope this was helpful. Best Wishes.