What causes large lump on right knee with tightness in glutes?
Patient: Hi, I am a a very fit and active lady in my early fifties and over the course of the last two months have a egg sized lump on the outside of my right knee. I have been to my GP and had an x-ray. This confirmed that it was not calcified. However, it is still there and causing discomfort when I walk and or bend. I used to run 4 times a week, but have stopped since the onset of this condition. I am also feeling a tightness in my glutes which tends to want to cause a twisting motion when I walk. Any thoughts on what this is and what can be done about it? Many thanks Doctor: Hello,  The lump outside the knee can be either a synovial cyst or lipoma or a sebaceous cyst.These all are soft tissue cysts.I shall advice you to ask for USG of this swelling.If any of the above diagnosis is there then it should be removed by surgery.  The feeling of tightness at gluteus region is most probably due to stretching of iliotibial tract at outer aspect of thigh.You may ask for a prescription of muscle relaxant from your doctor for this.  Hope I have answered your queries. Let me know if I can assist you further.  Take care  Regards, Dr. Mukesh Tiwari