Does anti-depressants interact alcohol?
Patient: My husband has been an alcoholic for many years.  His drinking, coupled with taking anti-depressants, led to a bipolar manic episode recently, resulting in a 2 week stay in a psych unit.  He immediately returned to drinking upon discharge.  He is now complaining of moderate edema in his ankles and calves.  Could this be a reaction to his new meds or could it reflect possible kidney failure? Doctor: Hi, your husband was taking antidepressants so it might be antidepressants induce manic episode.alcohol dependence and sleep disturbance may precipitate mood episode in future so it is better for him to avoid alcohol and get better sleep in night.edema feet might be due to antipsychotic medicine which he is receiving for manic symptoms, it might be due to other cause. Better you discuss it with your treating doctor he will find out the cause and manage it properly.hope this is helpful for you.Thank Dr Ramashanker YadavMD PsychiatryAhmedabad