What causes discoloration on the calves and numbness in the legs?
Patient: I have discoloration of the calf muscle bilaterally. Tingling and numbness down both legs to the middle toe on each side. The peripheral numbness has been the most important and disturbing symptom. Past history of high sedimentation rate(100-120 consistently) and splenomegaly. I weigh 140 lbs,. and its starting to worry me about my future ability to walk/ Do you have any idea? Thank you so very much! Noreen Doctor: Hello and welcome to ‘Ask A Doctor’ service. I have reviewed your query and here is my advice.  The discoloration with numbness can be related to blood clot or a spontaneous bleeding inside due to enlarged spleen.  Hope I have answered your query. Let me know if I can assist you further.