How long do i need to wait before i can take an oxycodone?
Patient: I have a spinal injury and was prescribed oxycodone for pain relief 10/325 (2x daily) and physical therapy.  I had to stop and switch to tramadol because i needed to study for a major exam. I took 50mg of tramadol at 8am this morning, but my back is starting to get painful. How long do I need to wait before I can take an oxycodone? I was told only not to take them together. My dr is unavailable right now, can you answer this question for me? Thanks Doctor: Hello and Welcome to ‘Ask A Doctor’ service. I have reviewed your query and here is my advice. You should wait at least 8 hours to take Oxycodone after the Tramadol use.  Hope this helps. Take care.