For what exact reason is Propeptide Type 1 Collagen test is carried out?
Patient: Hi. I had a blood test for some dental work I need to have done. The test is Propeptide Type I Collagen. Can you tell me exactly what this is for? I needed to take it because I took Fosamax for several years. I stopped taking the Fosamax in January. How long before it gets out of my body, if that s the purpose of the drug holiday. Thanks. Doctor: hellothnx for your query.you didnt mention ur age. the test u r mentioning indicates the bone turnover.Type I collagen is the predominant collagen in bone.it is used to evaluate and monitor the rate of bone resorption and formation to monitor some metabolic bone diseases such as osteoporosis.A “drug holiday” is a discontinuance of bisphosphonate like Fosamax for a length of time to achieve a reduction of risk of osteonecrosis of the jaw (ONJ). It is suggested that you consider interrupting bisphosphonate treatment for 3-4 weeks prior to dental surgery and restarting after bone healing.for patients who have taken an oral bisphosphonate for more than 3 years, discontinuation of the oral bisphosphonate for 3 months prior to oral surgery may reduce the risk. The bisphosphonate can be started again once osseous healing has occurred. hope this ans helpsRegardsDr. shesh