How can pyruvate kinase deficiency causing hemolytic anemia be treated?
Patient: Hi, may I answer your health queries right now ?  Please type your query here...my.daugter has pyruvate kinas e deficiency, an inherited enzyme deficiency that causes hemolytic anemia.   She has had her spleen removed eliminating the need for blood transfusions (except for during her pregnancy.  Are hickiesd Doctor: Hello,I understand your concern.I am Dr. Arun Tank, infectious diseases specialist, answering your query.Pyruvate kinase is enzyme. It is necessary for the integrity of the red blood cell wall.The person who is in the deficient state of enzyme will not sustain the integrity of the cell wall.It is inherited disease and there is no treatment for it. But transfusion can help replenish enzymes and help improve symptoms.Such types of patients should avoid factors which causes red cell lysis.I will be happy to answer your further concern, you can ask me on bit.ly/DrArun. Thank you.Dr Arun TankInfectious diseases specialist.