What causes a rising PSA with arm and shoulder pain?
Patient: My PSA has risen in less than a year from 0.9 to 3.88.  It has never been higher than 0.9.  Urologist has put me on an antibiotic, and wants to recheck in six weeks.  I have also been having arm and shoulder pain, muscle twitches all over, some shakiness.  Is it possible that I could have cancer, considering the short timeframe, or do you think it is just a bad infection?  I am 45 years old.  Could a prostate infection affect nerves in the body elsewhere?  My Neurologist thinks I have a Post Virus Syndrome attacking my body but this was before the PSA test..  He sent me to Urologist when I started having symptoms- hurting in that region and leakage after urination. Member Comments (1)  by RC03, Jun 24, 2011 04:59PM More information: digital exam was normal.  Neurological symptoms came on suddenly six months ago. Clear MRI brain and Cervical spine.  clear EMG as well.  I am on Cembalta for nerve pain.  My PSA was the first I have had since Aug. 10.  Dr. was looking for MS type illness. Doctor: HelloThanks for query .The pain in shoulder and arms can not be due to prostate infection .Your PSA levels which has raised from 0.9 to 3.88 can be considered as a normal variation as it has not raised above 4 which is considered to be a land mark to suspect cancer of prostate .The raised PSA is likely to be due to infection of prostate (Prostatitis) and can be controlled with long term course (6 Weeks) of appropriate antibiotic .As regards your doubt about MS it is most unlikely as your MRI brain is normal ..The possibility of generalized Viral Neuritis can be a considered and taking Methylcynocobalamine and other vitamin supplements should help to get relief from pain in arms and shoulders .