Suggest medication for depression while on NSAIDs
Patient: I am currently taking NSAID's for chronic back and neck pain with the occasional vicoden when it gets very intense. What antidepressant would be best for my depression? I've read SNRI's are better as SSRI's effects are diminished with NSAID and pain meds. Doctor: Hi Sir/MadamWelcome to Health Care MagicI can certainly understand your concern about the combined effect of NSAIDs and SSRIs , as you said it may reduce the effectiveness because of some cytokine receptor occupation by both the drugs, so there will be less receptors available for SSRIs But I can suggest you can start on desvenlafaxine which is an SNRI , as due to the  combined effect of norepinephrine and serotonin, you can get good results...But it is advisable not to stop this medicationBefore 6-9 months , even if you feel better as you may get relapse of the symptoms...If you stop the course incompletely, hope this information would help youPlease post your further questions if any, I will be always available to answer themThank youPost your further questions if any, I will available to take up your follow up questionsThank you