What causes knee pain while on Eliquis?
Patient: I was diagnosed with three pulmonary embolisms in my right lung. Since taking Eliquis I am having pain behind my right knee and my right leg is very heavy and pain when I walk. I become tired very quickly when I walk down the hall of my apartment building (about 60 yrds.) Is this normal with taking Eliquis 10mil twice a day? Doctor: Hello,  You haven't mentioned about your age first of all because that's important while thinking of differential diagnosis. You could have developed another clot which could be responsible for your symptoms.   I would suggest you to go for color Doppler.  Hope I have answered your query. Let me know if I can assist you further.  Take care  Regards, Dr Anuj Gupta, Spine Surgeon