Can an online doctor explain the histopathology report ?
Patient: Dear Sir, MY Histopathology report says : Gross Description: Multiple cores of tissuesand Microscopic Description says;    Metastatic carcinoma consistent with primary origin in an andrenocortical neoplasm   The Tumor cells express synaptophysin focally.They are immunonegative for CK, Melan A, chromogranins, HSA and inhibin,The Mib-1 Prolieferation index is 5%Are these reports sensitive Doctor: Hello,  You have not mentioned site of biopsy .Whatever may be site of biopsy this report shows malignancy there which has most probably come from adrenocortical area .it means that cancer has spread and has reached the site of biopsy. Adrenocortical area is situated just above kidney . Consult your oncologist for further guidance.