What causes elevated SGPT/SGOT/bilirubin while on tuberculosis treatment?
Patient: Hi, I am on undergoing tb treatment for past 2 weeks. My doctor advised sgpt,sgot and billirubin test after 15 days. The results of the tests are sgpt-58,sgot-70 and billirubin-0.9. Is it normal to have high levels of these while on tb treatment? What is the meaning of this please help? Doctor: Hi there,Thanks for using HCM.During the initial phase of treatment for tuberculosis medications like INH, Rifampicin, Pyrazinamide and ethionamide are used. Of these four drugs, the first three can affect the liver and cause the liver enzymes to raise.When it raises more than 2-3 times the upper limit of normal it is significant. When it is raised multiple folds, the medications are usually stopped.In your case it is not significantly raised.Moreover you have not mentioned about the baseline levels which is what the liver enzyme levels were before starting the treatment.I would advise you to get a ultrasound scan of the abdomen done.If you have the habit of drinking alcohol, you need to stop it.Is this answer helpful?