Trying to conceive, irregular periods, PCOD. Taken Ubifine, Clomifine, Foligraph. No follicle development
Patient: I am chitty from india iam trying to conceive since six months, i have irregular period and i am suffering from Pcod . doctor had given 5 ubifine tablets clomifine citrate and given injection FoliGraph r-hFSH of 75I.U./150 I.U.for 5th and 7 th day . after the ultrasound scan of my 9th day the size was only 12mm only my doctor had given one more injection Gm+hp 75 I.U in the 9th day.is it enough to do iui .now my doubt is it grows bigger in the next comming days . but last  month my folicle size is only 16mm in the 18th day but it releases. now i am fear about that. but last before month its size is 16mm in the10 day itself and it grows to 21 mm in the 16th day and releases . why my folicles are not developing the same way every month and iam taking Chrominac -A tables every day since 4 months. Doctor: Hello Good Evening,You said that you have PCOS (Polycystic ovary syndrome).PCOS produces symptoms in approximately 5% to 10% of women of reproductive age (12–45 years old). It is thought to be one of the leading causes of female sub-fertility and the most frequent endocrine problem in women of reproductive age.The principal features are anovulation, resulting in irregular menstruation, amenorrhea, ovulation-related infertility, and polycystic ovaries; excessive amounts or effects of androgenic (masculinizing) hormones, resulting in acne and hirsutism; and insulin resistance, often associated with obesity, Type 2 diabetes, and high cholesterol levels.The symptoms and severity of the syndrome vary greatly among affected women.In PCOS, there is a so-called "follicular arrest", i.e., several follicles develop to a size of 5–7 mm, but not further. No single follicle reaches the preovulatory size (16 mm or more) but you have 16 mm or more, so do not get tensed.Every cycle can not be the same, due to many physiological and hormonal effects, so keep patience and continue on treatment.So keep in touch with your gynecologist for continuation of the treatment and monitoring.Regards,Dr. Naresh Jain.