Why is a biopsy required for blood in urine when the CT scan was negative 4 months ago?
Patient: Risks with prostrate biopsy through the rectum. If my CT was negative 4 months ago and then had surgery for a very large prostate Discovered in the er due to blood in my urine and inability to urinate Why would they go in and take 18 punch biopsies when no mass has been seen. I m 60 and my psa went from 6.6 to 7.3. In 3 months.. Infection has been r/o and I want to be informed of the most up to date information. Thanks Doctor: Hello and Welcome to ‘Ask A Doctor’ service. I have reviewed your query and here is my advice.  The PSA level indicates that something is going on in your prostate. In lieu of radiological evidence, transrectal biopsies are more sensitive in finding cancer. The most important risks of the biopsies are bleeding and prostatitis.  Hope I have answered your query. Let me know if I can assist you further.