Can Diclofenac Sodium topical gel cause fluid retention?
Patient: Can Diclofenac sodium topical gel cause someone to retain fluid? A friend of mine has pedal edema with pain and someone gave her some of her prescription gel to help with the pain, but I m afraid that due to the sodiium aspect, it could increase the edema. Doctor: Dear patient Diclofenac gel absorption is very less through the skin. even  if absorbed  short term  use will not lead to kidney damage. So you need not to worry with topical use of diclofenac gel.