Can Mantoux cause persistent fever?
Patient: Hi DOctor, I donot have maor heatlh issues but last month i had fever....not knowing the reason.It was 102 and would come n go by itself...I have got all test done staring from typoid to malaria to Montaux...all are neg though i was positive to mantaux...doc did not treat me saying i donot have enuf symptoms to treat any disease....although my ESR is 80...and now i feel a hard lump inside my neck on left side...cant see it out side....Help Doctor: Hi, I see you have investigation reports in search of diagnosing fever of ? origin but except Mantoux all are not indicative for any thing. In presence of high ESR- 80mm/hr with a lump on Left side although more hard to feel are enough to suspect some chronic infection with a focus some where but unlikely Mantoux responsible for continued fever since you were looking for clue with  Mantoux test included.       Without waiting any additional symptom to manifest , I consider it would help  you and we doctors if you agree to undergo Aspiration Cytology or better still Histopathology of the hard lump you noted and special culture of possible bacterium at least to rule out Tuberculosis. please also add some info as your present age, occupation, country of stay, any migration, any drug history- present and past along with  the discussed investigation asap.