Liver panel levels are slightly off. Platelets count well below. US normal. Take seroquel and aspirin
Patient: I am concerned about my liver.  My annual liver panel numbers AST/ALT have been slightly off for at least the last five years.  Plus, I have had well below normal platelets for at least the last four years.  My doctor tested for hepatitis, and did an ultrasound of my liver/gall bladder.  Everything was normal.  Additionally, I have what appears to be classic Terry's nails.  However, I have no symptoms that I am aware of - no weight loss, jaundice, fatigue.  I am not overweight, don't smoke or drink any alcohol, an not diabetic, and I am extremely active - at least eight to ten hours of heavy cardio and weightlifting every week.  I also take 100mg of seroquel (bipolar) and up to four aspirin or advil a day for joint pain - I was diagnosed with ankylosing spondylitis in 2000. Doctor: Dear friend,I am Dr. (Col) R Karanwal, M.D. (Internal Medicine), Consultant Physician,  for your assistance.Thanks for reposing your faith in me and post your query on this website. I fully appreciate your concerns. 1.   All drugs which are metabolized (detoxified) by the liver, can also be toxic to liver. Aspirin and Advil are known to be toxic for liver, which manifests as raised ALT/AST levels.2.   Low platelet counts can either be a manifestation of ankylosing spondylosis or due to prolonged use of aspirin.3.  If I were your treating doctor, I would have prescribed medicines which are quite effective in anklyosing spondylosis. rather than simply continuing with pain-killers. Consult your doctor and discuss specific treatment for your chronic condition.Please feel free to revert back to me in case of further clarifications, if any.I am sure  that you will benefit from the advice.May I assure you that I am always available for your assistance.  My endeavor would always be to give you a sound medical advice,  to the best of my knowledge and vast experience.HAVE A NICE DAY AND A SPEEDY RECOVERY.Fond Regards,Dr.(Col)  R KaranwalMBBS; M.D. (Internal Medicine)Consultant Physician(PLEASE NOTE :- My opinion/advice is based SOLELY on the details provided by you.)