Have symptoms similar to SLE, ANA weakly positive. Symptoms persist, with new ones
Patient: I have been having many symptoms that are similar, if not dead on to those of SLE.  I had a positive ANA but when they did more blood work they said it was a weak postive and that was it.  No more tests nothing, but still the same symptoms persist a year and half later.  They were better for about a 5 month period but now starting again with new ones on top of the old symptoms. Doctor: you probably need a repeat ANA by immunofluorescence . that will give us a definite answer about your SLE. ANA weakly positive means that it has been done by elisa which is not the recommended method to do the test. what other symptoms do you have. do you have photosensitivity,skin rash, oral ulcers, ever had pleural effusion, CNS or renal symptoms-these are the symptoms of SLE.