What causes fever with rapid weight loss?
Patient: My wife(51 YEARS OLD) has been having temperature for now almost six weeks. Since last two weeks, the temperature has been ranging between 99 to 101 deg F. During hospitalization,following tests were carried out and they were all negative. OX 19,OX2,OX K,IGG,IGM, S.TYPHI(O,H),S.PARATYPHI(AH),S.PARATYPHIA(BH),ULTRSOUND OF ABDOMEN AND PELVIS,URINE CULTURE(NO GROWTH),CHICKUN GUNIA,RAPID MALERIA,CARDIAC COLOUR DOPLER,CT SCAN OF BRAIN,CHEST AND ABDOMEN,PAUL BUNNEL,PROCALCITONIN,CMV Igm Ab, PARANASAL SINUSES, IGG,IGM, ESR, P.C.R ETC. Following  tests have indicated possibility of tuberculosis, one out of three urine samples has shown ACID FAST BACILLI, TUBERCULIN TEST CHECKED AFTER ONE WEEK SHOWS SIZE OF 15 MM, WHILE THE TEST REPORT ON THE DATE OF TESTING HAS REPORTED 7MM. IVP TEST WHICH STATES,"THERE ARE CHANGES OF EARLY GRANULOMATOUS DISEASE IN RIGHT KIDNEY LIKE TUBERCULOSIS. Based upon the above three symptoms, she was prescribed AKT 4 drugs. This drug resulted into constipation, loss of appetite, which was prooved by increase SGPT to 285. AKT 4 was subsequently stopped after two weeks of use and SGPT came back to normal.  After stopping AKT 4, she was being given following drugs, combutol (1200mg) Levoflox (750 mg) Since last one week, one more drug (IV INJECTION KONAMYCIN 0.75gm ) was given and last two days, one more drug R-CIN 450mg was given. Inspite of all these drugs, she has been having temperature, although the appetite hs increased. After starting the IV injection and R-CIN 450 mg capsule, she has started vomiting and so we have stopped all the medicines since yesterday and approached a Hemeopathic doctor, who has advised to stopp all the elopatic drugs for three days. I seek your  expert opinion on the subject as my wife has lost @6 kg during this period and she is still having temperature to the extent of 101 max. Doctor: hi, I m glade to answer you.I think that the tuberculosis treatment have been successfull, and need time to eradicate tuberculosis, but a gastritis is widely expected and need Gastroscopy with biopsy.I would add to last tuberculosis treatment a Proton pomp inhibitor like pantoprazole 40 in the same time a Gastroscopy with biopsy is indicated.may my answer will helpfull