Can Deriphylline 2ml injection be administered every time during acute exacerbation?
Patient: hi doctor my mther is 45 years soffering from asthma n copd from last 5 years...she right now has severe wheezing and fever...we have given her injection deriphylline2ml im , i want to knw can we administer it everytime she has an acute exacerberation??? Doctor: Hello,  Well, it can overdose. It is generally recommended to be given no more than 4 times a day total dose of 300 mg per 24 hrs.; and 2 ml is on the large size of dosing.   Funny story: my mother had an overdose of it when she   1) started taking her recommended dose   2) took erythromycini which causes it to accumulate  3) stopped cigarettes which lower its metabolism when you stop   4) had the flu which lowers the metabolism of it but   5) won a casino jackpot and hyperventilated which triggered the seizure. So, a lot of factors can influence this drug.  Hope I have answered your query. Let me know if I can assist you further.  Take care  Regards, Dr Matt Wachsman, Addiction Medicine Specialist