What causes knots on thighs with fibromyalgia?
Patient: I can run my hands down my thighs when laying on my side and it is very very tender and I feel hard like knots. I have been told I have fibromyalgia back in 1992.. Could these be nodules? At times it s so hard to get a good night sleep. YYYY@YYYY Doctor: Hi, dearI have gone through your question. I can understand your concern. You have fibromyalgia in past.  Your lump may be due to some soft tissue tumor like lipoma, neurofibroma or dermatofibroma. You should go for biopsy of one of the lump.  It will give you exact diagnosis. Then you should take treatment accordingly. Hope I have answered your question, if you have doubt then I will be happy to answer. Thanks for using health care magic. Wish you a very good health.