Ia drinking cocktail daily affect the consumption of methadone hcl 5mg?
Patient: My 91 year old aunt was given a prescription for methadone hcl 5mg tablets for pain in her knee and hip, since replacement surgery is not an option. She was previously managing the pain with Advil. She has a half of a martini every day and wants to know if she must stop having her daily cocktail if she is going to take this medicine. Thank you. Doctor: Hello and Welcome to ‘Ask A Doctor’ service. I have reviewed your query and here is my advice.  Alcohol may increase the sedative action of methadone. No others interaction reported between methadone and alcohol and alcohol doesn’t affect the efficacy of methadone. However daily alcohol consumption is not good especially at this age!  Hope I have answered your query. Let me know if I can assist you further. Regards, Dr. Shinas Hussain