What causes severe leg pain at night?
Patient: I am having severe pain in my right leg from hip to calf...Keeps me up at night. Have seen an orthopedic doctor 3 times with no improvement. Had cortisone shot in right hip, put on motrin, and muscle relaxers. Not a real big pill person. then say it MAY be bursitis but I have mentioned 3 times that I have lumps on my thigh that is sore to the touch as well a few on my side of my right leg and they never bothered to even look at them let alone touch them, My concern is that I fear a blood clot somewhere. Any advice Doctor: Hello,  The location and movement of a pain give clues as to what is going on. and it's usually pretty obvious if it is the joint or the muscle or the butt or the hip joint.  There can be irritation of the sciatic nerve with nerve type pain the goes from the back down the buttock and down the back of the leg.  There can be muscle tone changes and this is the most common cause of nocturnal leg pain.   Sometimes potassium and/or magnesium supplements may help but muscle relaxants or Parkinson's disease drugs are more commonly useful.  Hope I have answered your query. Let me know if I can assist you further.  Take care  Regards, Dr Matt Wachsman, Addiction Medicine Specialist