Instruct: Identify the main and secondary category of Arxiv papers based on the titles and abstracts
Query: Excluded-Volume Effects in Tethered-Particle Experiments: Bead Size
  Matters   The tethered-particle method is a single-molecule technique that has been
used to explore the dynamics of a variety of macromolecules of biological
interest. We give a theoretical analysis of the particle motions in such
experiments. Our analysis reveals that the proximity of the tethered bead to a
nearby surface (the microscope slide) gives rise to a volume-exclusion effect,
resulting in an entropic force on the molecule. This force stretches the
molecule, changing its statistical properties. In particular, the proximity of
bead and surface brings about intriguing scaling relations between key
observables (statistical moments of the bead) and parameters such as the bead
size and contour length of the molecule. We present both approximate analytic
solutions and numerical results for these effects in both flexible and
semiflexible tethers. Finally, our results give a precise,
experimentally-testable prediction for the probability distribution of the
distance between the polymer attachment point and the center of the mobile
bead.

24
The categories of this paper are: dg-ga
0
The categories of this paper are: hep-ph
14
The categories of this paper are: math-ph
6
The categories of this paper are: astro-ph
11
The categories of this paper are: hep-lat
37
The categories of this paper are: supr-con
30
The categories of this paper are: q-alg
7
The categories of this paper are: hep-th
20
The categories of this paper are: acc-phys
23
The categories of this paper are: solv-int
5
The categories of this paper are: gr-qc
22
The categories of this paper are: chao-dyn
17
The categories of this paper are: q-fin
16
The categories of this paper are: stat
13
The categories of this paper are: quant-ph
4
The categories of this paper are: cond-mat