Instruct: Identify the main and secondary category of Arxiv papers based on the titles and abstracts
Query: An encryption-decryption framework for validating single-particle
  imaging   We propose an encryption-decryption framework for validating diffraction
intensity volumes reconstructed using single-particle imaging (SPI) with x-ray
free-electron lasers (XFELs) when the ground truth volume is absent. This
framework exploits each reconstructed volumes' ability to decipher latent
variables (e.g. orientations) of unseen sentinel diffraction patterns. Using
this framework, we quantify novel measures of orientation disconcurrence,
inconsistency, and disagreement between the decryptions by two independently
reconstructed volumes. We also study how these measures can be used to define
data sufficiency and its relation to spatial resolution, and the practical
consequences of focusing XFEL pulses to smaller foci. This framework overcomes
critical ambiguities in using Fourier Shell Correlation (FSC) as a validation
measure for SPI. Finally, we show how this encryption-decryption framework
naturally leads to an information-theoretic reformulation of the resolving
power of XFEL-SPI, which we hope will lead to principled frameworks for
experiment and instrument design.

29
The categories of this paper are: funct-an
35
The categories of this paper are: mtrl-th
27
The categories of this paper are: comp-gas
6
The categories of this paper are: astro-ph
31
The categories of this paper are: ao-sci
20
The categories of this paper are: acc-phys
9
The categories of this paper are: nlin
11
The categories of this paper are: hep-lat
10
The categories of this paper are: q-bio
26
The categories of this paper are: bayes-an
21
The categories of this paper are: adap-org
4
The categories of this paper are: cond-mat
7
The categories of this paper are: hep-th
2
The categories of this paper are: math
37
The categories of this paper are: supr-con
30
The categories of this paper are: q-alg