Instruct: Identify the main and secondary category of Arxiv papers based on the titles and abstracts
Query: Partial correlation analysis indicates causal relationships between
  GC-content, exon density and recombination rate in the human genome   {\bf Background}: Several features are known to correlate with the GC-content
in the human genome, including recombination rate, gene density and distance to
telomere. However, by testing for pairwise correlation only, it is impossible
to distinguish direct associations from indirect ones and to distinguish
between causes and effects. {\bf Results}: We use partial correlations to
construct partially directed graphs for the following four variables:
GC-content, recombination rate, exon density and distance-to-telomere.
Recombination rate and exon density are unconditionally uncorrelated, but
become inversely correlated by conditioning on GC-content. This pattern
indicates a model where recombination rate and exon density are two independent
causes of GC-content variation. {\bf Conclusions}: Causal inference and
graphical models are useful methods to understand genome evolution and the
mechanisms of isochore evolution in the human genome.

1
The categories of this paper are: cs
29
The categories of this paper are: funct-an
6
The categories of this paper are: astro-ph
21
The categories of this paper are: adap-org
5
The categories of this paper are: gr-qc
35
The categories of this paper are: mtrl-th
17
The categories of this paper are: q-fin
14
The categories of this paper are: math-ph
32
The categories of this paper are: atom-ph
27
The categories of this paper are: comp-gas
0
The categories of this paper are: hep-ph
2
The categories of this paper are: math
12
The categories of this paper are: nucl-th
15
The categories of this paper are: nucl-ex
11
The categories of this paper are: hep-lat
36
The categories of this paper are: cmp-lg