Instruct: Identify the main and secondary category of Arxiv papers based on the titles and abstracts
Query: On the performance of combined dichotomic predictors of natively
  unfolded proteins   The performance of single folding predictors and combination scores is
critically evaluated. We test mean packing, mean pairwise energy and the new
index gVSL2 on a dataset of 743 folded proteins and 81 natively unfolded
proteins. These predictors have an individual performance comparable or even
better than other proposed methods. We introduce here a strictly unanimous
score S_{SU} that combines them but leaves undecided those sequences
differently classified by two single predictors. The performance of the single
predictors on a dataset purged from the proteins left unclassified by S_{SU},
significantly increases, indicating that unclassified proteins are mainly false
predictions. Amino acid composition is the main determinant considered by these
predictors, therefore unclassified proteins have a composition compatible with
both folded and unfolded status. This is why purging a dataset from these
ambiguous proteins increases the performance of single predictors. The
percentage of proteins predicted as natively unfolded by S_{SU} in the three
kingdoms are: 4.1% for Bacteria, 1.0% for Archaea and 20.0% for Eukarya;
compatible with previous determinations. Evidence is given of a scaling law
relating the number of natively unfolded proteins with the total number of
proteins in a genome; a first estimate of the critical exponent is 1.95 +- 0.21

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The categories of this paper are: cond-mat
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The categories of this paper are: math-ph
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The categories of this paper are: patt-sol
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The categories of this paper are: quant-ph
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The categories of this paper are: chao-dyn
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The categories of this paper are: hep-ph
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The categories of this paper are: bayes-an
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The categories of this paper are: solv-int
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The categories of this paper are: astro-ph
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The categories of this paper are: q-alg
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The categories of this paper are: dg-ga
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The categories of this paper are: hep-lat
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The categories of this paper are: funct-an
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The categories of this paper are: alg-geom
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The categories of this paper are: gr-qc
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The categories of this paper are: econ