Instruct: Identify the main category of Medrxiv papers based on the titles and abstracts
Query: Aberrant Activation of the Mentalizing Brain System During Eye Gaze Discrimination in Bipolar Disorder Bipolar disorder (BD) is associated with a range of social cognitive deficits. This study investigated the functioning of the mentalizing brain system in BD probed by an eye gaze perception task during fMRI. Compared with healthy controls (n = 21), BD participants (n = 14) showed reduced preferential activation for self-directed gaze discrimination in the medial prefrontal cortex (mPFC) and temporo-parietal junction (TPJ), which was associated with poorer cognitive and social functioning. Aberrant functions of the mentalizing system should be further investigated as marker of social dysfunction and treatment targets.

HighlightsO_LISocial dysfunction in bipolar disorder (BD) may be due to altered mentalizing.
C_LIO_LIIndividuals with BD showed reduced activation in the mentalizing brain system.
C_LIO_LIAberrant activity of the mentalizing system was associated with poorer functioning.
C_LI
48
The categories of this paper are: critical
40
The categories of this paper are: geriatric
42
The categories of this paper are: occupational
28
The categories of this paper are: nutrition
31
The categories of this paper are: imaging
61
The categories of this paper are: dermatology
72
The categories of this paper are: urology
64
The categories of this paper are: ophthalmology
34
The categories of this paper are: therapy
51
The categories of this paper are: education
56
The categories of this paper are: research
19
The categories of this paper are: public
73
The categories of this paper are: toxicology
7
The categories of this paper are: emergency
49
The categories of this paper are: intensive
16
The categories of this paper are: immunology