Instruct: Identify the main and secondary category of Arxiv papers based on the titles and abstracts
Query: Determination of personalized diabetes treatment plans using a two-delay
  model   Diabetes cases worldwide have risen steadily over the past decades, lending
urgency to the search for more efficient, effective, and personalized ways to
treat the disease. Current treatment strategies, however, may fail to maintain
ultradian oscillations in blood glucose concentration, an important element of
a healthy alimentary system. Building upon recent successes in mathematical
modeling of the human glucose-insulin system, we show that both food intake and
insulin therapy likely demand increasingly precise control over insulin
sensitivity if oscillations at a healthy average glucose concentration are to
be maintained. We then suggest guidelines and personalized treatment options
for diabetic patients that maintain these oscillations. We show that for a type
II diabetic, both blood glucose levels can be controlled and healthy
oscillations maintained when the patient gets an hour of daily exercise and is
placed on a combination of Metformin and sulfonylurea drugs. We note that
insulin therapy and an additional hour of exercise will reduce the patient's
need for sulfonylureas. Results of a modeling analysis suggest that a typical
type I diabetic's blood glucose levels can be properly controlled with a
constant insulin infusion between 0.45 and 0.7 microU/(ml*min). Lastly, we note
that all suggested strategies rely on existing clinical techniques and
established treatment measures, and so could potentially be of immediate use in
the design of an artificial pancreas.

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The categories of this paper are: chem-ph
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The categories of this paper are: plasm-ph
17
The categories of this paper are: q-fin
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The categories of this paper are: ao-sci
21
The categories of this paper are: adap-org
11
The categories of this paper are: hep-lat
4
The categories of this paper are: cond-mat
16
The categories of this paper are: stat
22
The categories of this paper are: chao-dyn
23
The categories of this paper are: solv-int
5
The categories of this paper are: gr-qc
3
The categories of this paper are: physics
9
The categories of this paper are: nlin
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The categories of this paper are: supr-con
13
The categories of this paper are: quant-ph
1
The categories of this paper are: cs