Instruct: Identify the main and secondary category of Arxiv papers based on the titles and abstracts
Query: Diffusion-induced anisotropic cancer invasion: a novel experimental
  method based on tumour spheroids   Tumour invasion is strongly influenced by microenvironment and, among other
parameters, chemical stimuli play an important role. An innovative methodology
for the quantitative investigation of chemotaxis in vitro by live imaging of
morphology of cell spheroids, in 3D collagen gel, is presented here. The assay
was performed by using a chemotactic chamber to impose a controlled gradients
of nutrients (glucose) on spheroids, mimicking the chemotactic stimuli
naturally occurring in the proximity of blood vessels. Different tumoral cell
lines (PANC-1 and HT-1080) are compared to non-tumoral ones (NIH/3T3).
Morphology response is observed by means a Time-lapse workstation equipped with
an incubating system and quantified by image analysis techniques. Description
of invasion phenomena was based on an engineering approach, based on transport
phenomena concepts. As expected, NIH/3T3 spheroids are characterized by a
limited tendency of cells to invade the surrounding tissue, unlike PANC-1 and
HT-1080 that show relatively stronger response to gradients.

27
The categories of this paper are: comp-gas
5
The categories of this paper are: gr-qc
16
The categories of this paper are: stat
31
The categories of this paper are: ao-sci
33
The categories of this paper are: plasm-ph
8
The categories of this paper are: hep-ex
17
The categories of this paper are: q-fin
20
The categories of this paper are: acc-phys
21
The categories of this paper are: adap-org
19
The categories of this paper are: eess
14
The categories of this paper are: math-ph
11
The categories of this paper are: hep-lat
6
The categories of this paper are: astro-ph
26
The categories of this paper are: bayes-an
13
The categories of this paper are: quant-ph
34
The categories of this paper are: chem-ph