Instruct: Identify the main category of Biorxiv papers based on the titles and abstracts
Query: A widely applicable and cost-effective method for general and specific RNA-protein complex isolation Despite important methodological advances made in the past few years, a widely applicable, cost-effective and easily scalable procedure that can be routinely used to isolate ribonucleoprotein complexes (RNPs) remains elusive. We describe a versatile method that connects aspects of existing methods in a workflow optimized to reach the above goals and called it "Silica-based Acidic Phase Separation (SAPS)-capture". To validate the method, the 18S rRNP of S. cerevisiae was captured. To illustrate its applicability, we isolated a repertoire of RNPs in A. thaliana. This procedure can provide the community with a powerful tool to advance the study of ribonomes and RNPs in any organism or tissue type.
5
The categories of this paper are: cell
19
The categories of this paper are: epidemiology
24
The categories of this paper are: cancer
8
The categories of this paper are: genomics
20
The categories of this paper are: pharmacology
7
The categories of this paper are: ecology
30
The categories of this paper are: scientific
0
The categories of this paper are: genetics
25
The categories of this paper are: bioengineering
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The categories of this paper are: plant
13
The categories of this paper are: animal
26
The categories of this paper are: biochemistry
3
The categories of this paper are: evolutionary
32
The categories of this paper are: zoology
21
The categories of this paper are: toxicology
12
The categories of this paper are: behavior