Instruct: Identify the main and secondary category of Arxiv papers based on the titles and abstracts
Query: Collective Properties of a Transcription Initiation Model under Varying
  Environment   The dynamics of gene transcription is tightly regulated in eukaryotes. Recent
experiments have revealed various kinds of transcriptional dynamics, such as
RNA polymerase II pausing, that involves regulation at the transcription
initiation stage, and the choice of different regulation pattern is closely
related to the physiological functions of the target gene. Here we consider a
simplified model of transcription initiation, a process including the assembly
of transcription complex and the pausing and releasing of the RNA polymerase
II. Focusing on the collective behaviors on a population level, we explore
potential regulatory functions this model can offer. These functions include
fast and synchronized response to environmental change, or long-term memory
about the transcriptional status. As a proof of concept we also show that, by
selecting different control mechanisms cells can adapt to different
environments. These findings may help us better understand the design
principles of transcriptional regulation.

26
The categories of this paper are: bayes-an
5
The categories of this paper are: gr-qc
27
The categories of this paper are: comp-gas
35
The categories of this paper are: mtrl-th
37
The categories of this paper are: supr-con
9
The categories of this paper are: nlin
11
The categories of this paper are: hep-lat
33
The categories of this paper are: plasm-ph
28
The categories of this paper are: alg-geom
14
The categories of this paper are: math-ph
25
The categories of this paper are: patt-sol
6
The categories of this paper are: astro-ph
23
The categories of this paper are: solv-int
32
The categories of this paper are: atom-ph
7
The categories of this paper are: hep-th
34
The categories of this paper are: chem-ph