Instruct: Identify the main and secondary category of Arxiv papers based on the titles and abstracts
Query: A whole-body multi-scale mathematical model for dynamic simulation of
  the metabolism in man   We propose a whole-body model of the metabolism in man as well as a
generalized approach for modeling metabolic networks. Using this approach, we
are able to write a large metabolic network in a systematic and compact way. We
demonstrate the approach using a whole-body model of the metabolism of the
three macronutrients, carbohydrates, proteins and lipids. The model contains 7
organs, 16 metabolites and 31 enzymatic reactions. All reaction rates are
described by Michaelis-Menten kinetics with an addition of a hormonal regulator
based on the two hormones insulin and glucagon. We incorporate ingestion of
food in order to simulate metabolite concentrations during the feed-fast cycle.
The model can simulate several days due to the inclusion of storage forms
(glycogen, muscle protein and lipid droplets), that can be depleted if food is
not ingested regularly. A physiological model incorporating complex cellular
metabolism and whole-body mass dynamics can be used in virtual clinical trials.
Such trials can be used to improve the development of medicine, treatment
strategies such as control algorithms, and increase the likelihood of a
successful clinical trial.

11
The categories of this paper are: hep-lat
13
The categories of this paper are: quant-ph
1
The categories of this paper are: cs
36
The categories of this paper are: cmp-lg
37
The categories of this paper are: supr-con
33
The categories of this paper are: plasm-ph
4
The categories of this paper are: cond-mat
12
The categories of this paper are: nucl-th
18
The categories of this paper are: econ
26
The categories of this paper are: bayes-an
8
The categories of this paper are: hep-ex
24
The categories of this paper are: dg-ga
9
The categories of this paper are: nlin
22
The categories of this paper are: chao-dyn
20
The categories of this paper are: acc-phys
0
The categories of this paper are: hep-ph