Instruct: Identify the main and secondary category of Arxiv papers based on the titles and abstracts
Query: Understanding the determinants of stability and folding of small
  globular proteins from their energetics   The results of minimal model calculations suggest that the stability and the
kinetic accessibility of the native state of small globular proteins are
controlled by few "hot" sites. By mean of molecular dynamics simulations around
the native conformation, which simulate the protein and the surrounding solvent
at full--atom level, we generate an energetic map of the equilibrium state of
the protein and simplify it with an Eigenvalue decomposition. The components of
the Eigenvector associated with the lowest Eigenvalue indicate which are the
"hot" sites responsible for the stability and for the fast folding of the
protein. Comparison of these predictions with the results of mutatgenesis
experiments, performed for five small proteins, provide an excellent agreement.

32
The categories of this paper are: atom-ph
28
The categories of this paper are: alg-geom
6
The categories of this paper are: astro-ph
21
The categories of this paper are: adap-org
37
The categories of this paper are: supr-con
20
The categories of this paper are: acc-phys
29
The categories of this paper are: funct-an
8
The categories of this paper are: hep-ex
12
The categories of this paper are: nucl-th
26
The categories of this paper are: bayes-an
0
The categories of this paper are: hep-ph
13
The categories of this paper are: quant-ph
15
The categories of this paper are: nucl-ex
30
The categories of this paper are: q-alg
17
The categories of this paper are: q-fin
25
The categories of this paper are: patt-sol