Instruct: Identify the main and secondary category of Arxiv papers based on the titles and abstracts
Query: Protein-mediated DNA Loop Formation and Breakdown in a Fluctuating
  Environment   Living cells provide a fluctuating, out-of-equilibrium environment in which
genes must coordinate cellular function. DNA looping, which is a common means
of regulating transcription, is very much a stochastic process; the loops arise
from the thermal motion of the DNA and other fluctuations of the cellular
environment. We present single-molecule measurements of DNA loop formation and
breakdown when an artificial fluctuating force, applied to mimic a fluctuating
cellular environment, is imposed on the DNA. We show that loop formation is
greatly enhanced in the presence of noise of only a fraction of $k_B T$, yet
find that hypothetical regulatory schemes that employ mechanical tension in the
DNA--as a sensitive switch to control transcription--can be surprisingly robust
due to a fortuitous cancellation of noise effects.

27
The categories of this paper are: comp-gas
5
The categories of this paper are: gr-qc
13
The categories of this paper are: quant-ph
11
The categories of this paper are: hep-lat
35
The categories of this paper are: mtrl-th
2
The categories of this paper are: math
14
The categories of this paper are: math-ph
36
The categories of this paper are: cmp-lg
16
The categories of this paper are: stat
31
The categories of this paper are: ao-sci
21
The categories of this paper are: adap-org
15
The categories of this paper are: nucl-ex
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The categories of this paper are: eess
20
The categories of this paper are: acc-phys
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The categories of this paper are: patt-sol
18
The categories of this paper are: econ