Instruct: Identify the main and secondary category of Arxiv papers based on the titles and abstracts
Query: EPIC-Survival: End-to-end Part Inferred Clustering for Survival
  Analysis, Featuring Prognostic Stratification Boosting   Histopathology-based survival modelling has two major hurdles. Firstly, a
well-performing survival model has minimal clinical application if it does not
contribute to the stratification of a cancer patient cohort into different risk
groups, preferably driven by histologic morphologies. In the clinical setting,
individuals are not given specific prognostic predictions, but are rather
predicted to lie within a risk group which has a general survival trend. Thus,
It is imperative that a survival model produces well-stratified risk groups.
Secondly, until now, survival modelling was done in a two-stage approach
(encoding and aggregation). The massive amount of pixels in digitized whole
slide images were never utilized to their fullest extent due to technological
constraints on data processing, forcing decoupled learning. EPIC-Survival
bridges encoding and aggregation into an end-to-end survival modelling
approach, while introducing stratification boosting to encourage the model to
not only optimize ranking, but also to discriminate between risk groups. In
this study we show that EPIC-Survival performs better than other approaches in
modelling intrahepatic cholangiocarcinoma, a historically difficult cancer to
model. Further, we show that stratification boosting improves further improves
model performance, resulting in a concordance-index of 0.880 on a held-out test
set. Finally, we were able to identify specific histologic differences, not
commonly sought out in ICC, between low and high risk groups.

13
The categories of this paper are: quant-ph
4
The categories of this paper are: cond-mat
27
The categories of this paper are: comp-gas
21
The categories of this paper are: adap-org
5
The categories of this paper are: gr-qc
12
The categories of this paper are: nucl-th
17
The categories of this paper are: q-fin
30
The categories of this paper are: q-alg
28
The categories of this paper are: alg-geom
6
The categories of this paper are: astro-ph
26
The categories of this paper are: bayes-an
34
The categories of this paper are: chem-ph
37
The categories of this paper are: supr-con
23
The categories of this paper are: solv-int
11
The categories of this paper are: hep-lat
0
The categories of this paper are: hep-ph