Instruct: Identify the main and secondary category of Arxiv papers based on the titles and abstracts
Query: Human olfactory receptor 17-40 as active part of a nanobiosensor: A
  microscopic investigation of its electrical properties   Increasing attention has been recently devoted to protein-based
nanobiosensors. The main reason is the huge number of possible technological
applications, going from drug detection to cancer early diagnosis. Their
operating model is based on the protein activation and the corresponding
conformational change, due to the capture of an external molecule, the
so-called ligand. Recent measurements, performed with different techniques on
human 17-40 olfactory receptor, evidenced a very narrow window of response in
respect of the odour concentration. This is a crucial point for understanding
whether the use of this olfactory receptor as sensitive part of a nanobiosensor
is a good choice. In this paper we investigate the topological and electrical
properties of the human olfactory receptor 17-40 with the objective of
providing a microscopic interpretation of available experiments. To this
purpose, we model the protein by means of a graph able to capture the mean
features of the 3D backbone structure. The graph is then associated with an
equivalent impedance network, able to evaluate the impedance spectra of the
olfactory receptor, in its native and activated state. We assume a topological
origin of the different protein electrical responses to different ligand
concentrations: In this perspective all the experimental data are collected and
interpreted satisfactorily within a unified scheme, also useful for application
to other proteins.

11
The categories of this paper are: hep-lat
6
The categories of this paper are: astro-ph
21
The categories of this paper are: adap-org
15
The categories of this paper are: nucl-ex
24
The categories of this paper are: dg-ga
9
The categories of this paper are: nlin
27
The categories of this paper are: comp-gas
32
The categories of this paper are: atom-ph
18
The categories of this paper are: econ
8
The categories of this paper are: hep-ex
25
The categories of this paper are: patt-sol
23
The categories of this paper are: solv-int
20
The categories of this paper are: acc-phys
7
The categories of this paper are: hep-th
22
The categories of this paper are: chao-dyn
5
The categories of this paper are: gr-qc