Instruct: Identify the main and secondary category of Arxiv papers based on the titles and abstracts
Query: Adsorption models of hybridization and post-hybridisation behaviour on
  oligonucleotide microarrays   Analysis of data from an Affymetrix Latin Square spike-in experiment
indicates that measured fluorescence intensities of features on an
oligonucleotide microarray are related to spike-in RNA target concentrations
via a hyperbolic response function, generally identified as a Langmuir
adsorption isotherm. Furthermore the asymptotic signal at high spike-in
concentrations is almost invariably lower for a mismatch feature than for its
partner perfect match feature. We survey a number of theoretical adsorption
models of hybridization at the microarray surface and find that in general they
are unable to explain the differing saturation responses of perfect and
mismatch features. On the other hand, we find that a simple and consistent
explanation can be found in a model in which equilibrium hybridization followed
by partial dissociation of duplexes during the post-hybridization washing
phase.

7
The categories of this paper are: hep-th
33
The categories of this paper are: plasm-ph
21
The categories of this paper are: adap-org
20
The categories of this paper are: acc-phys
25
The categories of this paper are: patt-sol
11
The categories of this paper are: hep-lat
17
The categories of this paper are: q-fin
29
The categories of this paper are: funct-an
36
The categories of this paper are: cmp-lg
3
The categories of this paper are: physics
34
The categories of this paper are: chem-ph
0
The categories of this paper are: hep-ph
31
The categories of this paper are: ao-sci
18
The categories of this paper are: econ
35
The categories of this paper are: mtrl-th
8
The categories of this paper are: hep-ex