Instruct: Identify the main category of Biorxiv papers based on the titles and abstracts
Query: Cortical representation of touch in silico With its six layers and ~12000 neurons, a cortical column is a complex network whose function is plausibly greater than the sum of its constituents. Functional characterization of its network components will require going beyond the brute-force modulation of the neural activity of a small group of neurons. Here we introduce an open-source, biologically inspired, computationally efficient network model of the somatosensory cortexs granular and supragranular layers after reconstructing the barrel cortex in soma resolution. Comparisons of the network activity to empirical observations showed that the in silico network replicates the known properties of touch representations and whisker deprivation-induced changes in synaptic strength induced in vivo. Simulations show that the history of the membrane potential acts as a spatial filter that determines the presynaptic population of neurons contributing to a post-synaptic action potential; this spatial filtering might be critical for synaptic integration of top-down and bottom-up information.
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The categories of this paper are: ecology
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The categories of this paper are: microbiology
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The categories of this paper are: biophysics
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The categories of this paper are: developmental
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The categories of this paper are: synthetic
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The categories of this paper are: bioengineering
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The categories of this paper are: plant
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The categories of this paper are: cancer
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The categories of this paper are: zoology
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The categories of this paper are: paleontology
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The categories of this paper are: scientific
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The categories of this paper are: education
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The categories of this paper are: pathology
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The categories of this paper are: cell
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The categories of this paper are: genomics
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The categories of this paper are: immunology