Instruct: Identify the main and secondary category of Arxiv papers based on the titles and abstracts
Query: Protein and hydration-water dynamics are decoupled: A new model
  connecting dynamics and biochemical function is required   Water plays a major role in bio-systems, greatly contributing to determine
their structure, stability and even function. It is well know, for instance,
that proteins require a minimum amount of water to be functionally active.
Since the biological functions of proteins involve changes of conformation, and
sometimes chemical reactions, it is natural to expect a connection of these
functions with dynamical properties of the coupled system of proteins and their
hydration water. However, despite many years of intensive research, the
detailed nature of protein - hydration water interactions, and their effect on
the biochemical activity of proteins through peculiar dynamical effects, is
still partly unknown. In particular, models proposed so far, fail to explain
the full set of experimental data. The well-accepted 'protein dynamical
transition' scenario is based on perfect coupling between the dynamics of
proteins and of their hydration water, which has never been confuted
experimentally. We present high-energy resolution elastic neutron scattering
measurements of the atomistic dynamics of the model protein, lysozyme, in water
that were carried out on the IN16B spectrometer at the Institut Laue-Langevin
in Grenoble, France. These show for the first time that the dynamics of
proteins and of their hydration water are actually de-coupled. This important
result militates against the well-accepted scenario, and requires a new model
to link protein dynamics to the dynamics of its hydration water, and, in turn,
to biochemical function.

8
The categories of this paper are: hep-ex
32
The categories of this paper are: atom-ph
18
The categories of this paper are: econ
27
The categories of this paper are: comp-gas
1
The categories of this paper are: cs
14
The categories of this paper are: math-ph
21
The categories of this paper are: adap-org
33
The categories of this paper are: plasm-ph
20
The categories of this paper are: acc-phys
36
The categories of this paper are: cmp-lg
9
The categories of this paper are: nlin
4
The categories of this paper are: cond-mat
17
The categories of this paper are: q-fin
22
The categories of this paper are: chao-dyn
13
The categories of this paper are: quant-ph
26
The categories of this paper are: bayes-an