Instruct: Identify the main and secondary category of Arxiv papers based on the titles and abstracts
Query: Polarisation of cells and soft objects driven by mechanical
  interactions: Consequences for migration and chemotaxis   We study a generic model for the polarisation and motility of self-propelled
soft objects, biological cells or biomimetic systems, interacting with a
viscous substrate. The active forces generated by the cell on the substrate are
modelled by means of oscillating force multipoles at the cell-substrate
interface. Symmetry breaking and cell polarisation for a range of cell sizes
naturally `emerge' from long range mechanical interactions between oscillating
units, mediated both by the intracellular medium and the substrate. However,
the harnessing of cell polarisation for motility requires substrate-mediated
interactions. Motility can be optimised by adapting the oscillation frequency
to the relaxation time of the system or when the substrate and cell viscosities
match. Cellular noise can destroy mechanical coordination between
force-generating elements within the cell, resulting in sudden changes of
polarisation. The persistence of the cell's motion is found to depend on the
cell size and the substrate viscosity. Within such a model, chemotactic
guidance of cell motion is obtained by directionally modulating the persistence
of motion, rather than by modulating the instantaneous cell velocity, in a way
that resembles the run and tumble chemotaxis of bacteria.

25
The categories of this paper are: patt-sol
28
The categories of this paper are: alg-geom
30
The categories of this paper are: q-alg
12
The categories of this paper are: nucl-th
27
The categories of this paper are: comp-gas
29
The categories of this paper are: funct-an
10
The categories of this paper are: q-bio
17
The categories of this paper are: q-fin
11
The categories of this paper are: hep-lat
21
The categories of this paper are: adap-org
32
The categories of this paper are: atom-ph
7
The categories of this paper are: hep-th
35
The categories of this paper are: mtrl-th
34
The categories of this paper are: chem-ph
5
The categories of this paper are: gr-qc
13
The categories of this paper are: quant-ph