Instruct: Identify the main category of Medrxiv papers based on the titles and abstracts
Query: Paediatric major incident triage and the use of machine learning techniques to develop an alternative triage tool with improved performance characteristics. BackgroundTriage is a key principle in the effective management of major incidents. However, there is an increasing body of evidence demonstrating that existing paediatric methods are associated with high rates of under-triage and are not fit for purpose. The aim of this study was to derive a novel paediatric triage tool using machine learning (ML) techniques.

MethodsThe United Kingdom Trauma Audit Research Network (TARN) database was interrogated for all paediatric patients aged under 16 years for the ten-year period 2008-2017. Patients were categorised as Priority One if they received one or more life-saving interventions from a previously defined list. Six ML algorithms were investigated for identifying patients as Priority One. Subsequently, the best performing model was chosen for further development using a risk score approach and clinically relevant modifications in order to derive a novel triage tool (LASSO M2).

Using patients with complete pre-hospital physiological data, a comparative analysis was then performed comparing this to existing pre-hospital paediatric major incident triage tools. Performance was evaluated using sensitivity, specificity, under-triage (1-sensitivity) and over-triage (1-positive predictive value).

ResultsComplete physiological data were available for 4962 patients. The LASSO M2 model demonstrated the best performance at identifying paediatric patients in need of life-saving intervention, sensitivity 88.8% (95% CI 85.5, 91.5) and was associated with the lowest rate of under-triage, 11.2% (8.5, 14.5). In contrast, the Paediatric Triage Tape and JumpSTART both had poor sensitivity when identifying those requiring life-saving intervention (36.1% (31.8, 40.7) and 44.7% (40.2, 49.4)) respectively.

ConclusionThe ML derived triage tool (LASSO M2) outperforms existing methods of paediatric major incident triage at identifying patients in need of life-saving intervention. Prior to its recommendation for clinical use, further work is required to externally validate its performance and undertake a feasibility assessment in a clinical context.

What is known about this topicChildren are frequently involved in all types of major incidents. A key principle in their management is triage, the process of prioritising patients on the basis of their clinical acuity.

Unlike in the adult population, there are currently only a limited number of paediatric triage tools for use in a major incident, with a paucity of evidence supporting their use.

A recent comparative analysis demonstrated that the adult triage tool, the MPTT-24, outperformed all existing pre-hospital paediatric triage tools at determining the Priority One paediatric patient.

What this study addsWe have applied machine learning algorithms to derive a novel triage tool, the LASSO M2.

This triage tool demonstrated an absolute increase in sensitivity of 52{middle dot}7% over the existing UK method of pre-hospital paediatric major incident triage, the Paediatric Triage Tape.

This study has demonstrated that utilising additional parameters out with patient physiology, can lead to a marked improvement in triage tool performance.
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The categories of this paper are: pediatrics
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The categories of this paper are: obstetrics
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The categories of this paper are: ophthalmology
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The categories of this paper are: critical