Instruct: Identify the main category of Medrxiv papers based on the titles and abstracts
Query: Genomic surveillance reveals the emergence of SARS-CoV-2 Lineage A from Islamabad Pakistan The lineage A of SARS-CoV-2 has been around the world since the start of the pandemic. In Pakistan the last case of lineage A was reported in April, 2021 since then no case has been reported. In November, 2021 during routine genomic surveillance at National Institute of Health we have found 07 cases of lineage A from Islamabad, Pakistan. The study reports two novel deletions in the spike glycoprotein. One 09 amino acid deletion (68-76 a.a) is found in the S1 subunit while another 10 amino acid deletion (679-688 a.a) observed at the junction of S1/S2 referred as furin cleavage site. The removal of furin cleavage site may result in impaired virus replication thus decreasing its pathogenesis. The actual impact of these two deletions on the virus replication and disease dynamics needs to be studied in detail. Moreover, the enhanced genomic surveillance will be required to track the spread of this lineage in other parts of the country.
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The categories of this paper are: neurology
48
The categories of this paper are: critical
32
The categories of this paper are: rehabilitation
57
The categories of this paper are: primary
60
The categories of this paper are: addiction
9
The categories of this paper are: diseases
41
The categories of this paper are: nephrology
29
The categories of this paper are: anesthesia
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The categories of this paper are: sports
66
The categories of this paper are: dentistry
51
The categories of this paper are: education
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The categories of this paper are: medicine
73
The categories of this paper are: toxicology
70
The categories of this paper are: otolaryngology
30
The categories of this paper are: radiology
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The categories of this paper are: nursing