Instruct: Identify the main category of Biorxiv papers based on the titles and abstracts
Query: The architecture and operating mechanism of a cnidarian stinging organelle The stingers of jellyfish, sea anemones and other cnidarians, known as nematocysts, are remarkable cellular weapons used for both predation and defense1. Nematocysts are specialized organelles which consist of a pressurized capsule containing a coiled harpoon-like thread2. These structures are in turn built within specialized cells known as nematocytes3. When triggered4, the capsule explosively discharges, ejecting the coiled thread which punctures the target and rapidly elongates by turning inside out in a process called eversion5,6. Due to the structural complexity of the thread and the extreme speed of discharge, the precise mechanics of nematocyst firing have remained elusive7. Here, using a combination of live and super-resolution imaging, 3D electron microscopy and genetic perturbations, we define the step-by-step sequence of nematocyst operation in the model sea anemone Nematostella vectensis. This analysis reveals the complex biomechanical transformations underpinning the operating mechanism of nematocysts, one of the natures most exquisite biological micro-machines. Further, this study will provide insight into the form and function of related cnidarian organelles and serve as a template for the design of bioinspired microdevices.
21
The categories of this paper are: toxicology
24
The categories of this paper are: cancer
0
The categories of this paper are: genetics
31
The categories of this paper are: paleontology
3
The categories of this paper are: evolutionary
8
The categories of this paper are: genomics
4
The categories of this paper are: neuroscience
25
The categories of this paper are: bioengineering
9
The categories of this paper are: synthetic
30
The categories of this paper are: scientific
6
The categories of this paper are: plant
16
The categories of this paper are: microbiology
15
The categories of this paper are: developmental
27
The categories of this paper are: pathology
13
The categories of this paper are: animal
23
The categories of this paper are: immunology