Instruct: Identify the main and secondary category of Arxiv papers based on the titles and abstracts
Query: Universal Sequence Replication, Reversible Polymerization and Early
  Functional Biopolymers: A Model for the Initiation of Prebiotic Sequence
  Evolution   Many models for the origin of life have focused on understanding how
evolution can drive the refinement of a preexisting enzyme, such as the
evolution of efficient replicase activity. Here we present a model for what
was, arguably, an even earlier stage of chemical evolution, when polymer
sequence diversity was generated and sustained before, and during, the onset of
functional selection. The model includes regular environmental cycles (e.g.
hydration-dehydration cycles) that drive polymers between times of replication
and functional activity, which coincide with times of different monomer and
polymer diffusivity. Kinetic Monte Carlo simulations demonstrate that this
proposed prebiotic scenario provides a robust mechanism for the exploration of
sequence space. Introduction of a polymer sequence with monomer synthetase
activity illustrates that functional sequences can become established in a
preexisting pool of otherwise non-functional sequences. Functional selection
does not dominate system dynamics and sequence diversity remains high,
permitting the emergence and spread of more than one functional sequence. It is
also observed that polymers spontaneously form clusters in simulations where
polymers diffuse more slowly than monomers, a feature that is reminiscent of a
previous proposal that the earliest stages of life could have been defined by
the collective evolution of a system-wide cooperation of polymer aggregates.
Overall, the results presented demonstrate the merits of considering plausible
prebiotic polymer chemistries and environments that would have allowed for the
rapid turnover of monomer resources and for regularly varying monomer/polymer
diffusivities.

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The categories of this paper are: atom-ph
14
The categories of this paper are: math-ph
11
The categories of this paper are: hep-lat
16
The categories of this paper are: stat
36
The categories of this paper are: cmp-lg
34
The categories of this paper are: chem-ph
0
The categories of this paper are: hep-ph
30
The categories of this paper are: q-alg
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The categories of this paper are: supr-con
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The categories of this paper are: funct-an
13
The categories of this paper are: quant-ph
33
The categories of this paper are: plasm-ph
2
The categories of this paper are: math
9
The categories of this paper are: nlin
22
The categories of this paper are: chao-dyn
4
The categories of this paper are: cond-mat