Instruct: Identify the main category of Biorxiv papers based on the titles and abstracts
Query: Reciprocal representation of encoded features by cortical excitatory and inhibitory neuronal populations. In the cortex, the interplay between excitation and inhibition determines the fidelity of neuronal representations 1-8. However, while the receptive fields of excitatory neurons are often fine-tuned to the encoded features 9-12, the principles governing the tuning of inhibitory neurons are still elusive 13-21. We addressed this problem by recording populations of neurons in the postsubiculum (PoSub), a cortical area where the receptive fields of most excitatory neurons correspond to a specific head-direction (HD) 12,22-25. In contrast to PoSub-HD cells, the tuning of fast-spiking (FS) cells, the largest class of cortical inhibitory neurons 26-28, was broad and heterogeneous. However, we found that PoSub-FS cell tuning curves were often fine-tuned in the spatial frequency domain, which resulted in various radial symmetries in their HD tuning. In addition, the average frequency spectrum of PoSub-FS cell populations was virtually indistinguishable from that of PoSub-HD cells but different from that of the upstream thalamic HD cells, suggesting that this population co-tuning in the frequency domain has a local origin. Two observations corroborated this hypothesis. First, PoSub-FS cell tuning was independent of upstream thalamic inputs. Second, PoSub-FS cell tuning was tightly coupled to PoSub-HD cell activity even during sleep. Together, these findings provide evidence that the resolution of neuronal tuning is an intrinsic property of local cortical networks, shared by both excitatory and inhibitory cell populations. We hypothesize that this reciprocal feature encoding supports two parallel streams of information processing in thalamocortical networks.
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The categories of this paper are: physiology
16
The categories of this paper are: microbiology
29
The categories of this paper are: education
19
The categories of this paper are: epidemiology
7
The categories of this paper are: ecology
27
The categories of this paper are: pathology
28
The categories of this paper are: communication
0
The categories of this paper are: genetics
23
The categories of this paper are: immunology
2
The categories of this paper are: biology
12
The categories of this paper are: behavior
9
The categories of this paper are: synthetic
26
The categories of this paper are: biochemistry
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The categories of this paper are: paleontology
32
The categories of this paper are: zoology
24
The categories of this paper are: cancer