Instruct: Identify the main and secondary category of Arxiv papers based on the titles and abstracts
Query: Force Modulating Dynamic Disorder: Physical Theory of Catch-slip bond
  Transitions in Receptor-Ligand Forced Dissociation Experiments   Recently experiments showed that some adhesive receptor-ligand complexes
increase their lifetimes when they are stretched by mechanical force, while the
force increase beyond some thresholds their lifetimes decrease. Several
specific chemical kinetic models have been developed to explain the intriguing
transitions from the "catch-bonds" to the "slip-bonds". In this work we suggest
that the counterintuitive forced dissociation of the complexes is a typical
rate process with dynamic disorder. An uniform one-dimension force modulating
Agmon-Hopfield model is used to quantitatively describe the transitions
observed in the single bond P-selctin glycoprotein ligand
1(PSGL-1)$-$P-selectin forced dissociation experiments, which were respectively
carried out on the constant force [Marshall, {\it et al.}, (2003) Nature {\bf
423}, 190-193] and the force steady- or jump-ramp [Evans {\it et al.}, (2004)
Proc. Natl. Acad. Sci. USA {\bf 98}, 11281-11286] modes. Our calculation shows
that the novel catch-slip bond transition arises from a competition of the two
components of external applied force along the dissociation reaction coordinate
and the complex conformational coordinate: the former accelerates the
dissociation by lowering the height of the energy barrier between the bound and
free states (slip), while the later stabilizes the complex by dragging the
system to the higher barrier height (catch).

37
The categories of this paper are: supr-con
8
The categories of this paper are: hep-ex
20
The categories of this paper are: acc-phys
32
The categories of this paper are: atom-ph
15
The categories of this paper are: nucl-ex
33
The categories of this paper are: plasm-ph
12
The categories of this paper are: nucl-th
23
The categories of this paper are: solv-int
7
The categories of this paper are: hep-th
14
The categories of this paper are: math-ph
3
The categories of this paper are: physics
16
The categories of this paper are: stat
36
The categories of this paper are: cmp-lg
0
The categories of this paper are: hep-ph
17
The categories of this paper are: q-fin
1
The categories of this paper are: cs