Instruct: Identify the main and secondary category of Arxiv papers based on the titles and abstracts
Query: Directed destabilization of lysozyme in protic ionic liquids reveals a
  compact, low energy, soluble, reversibly-unfolding (pre-fibril) state   Recent demonstrations of extraordinary stabilization of proteins in mobile
protic [1] and aprotic [2] ionic liquid solutions at ambient temperatures have
raised hopes of new biopreservation and drug transportation technologies. Here
we examine the relation of folded protein stability to the state of the
transferred proton [1], as determined by the N-H proton chemical shift, d(N-H).
We identify a range of d(N-H) in which the unfolded lysozyme refolds 97%.
Exceeding the stability range in the acid direction leads to the sudden
formation and stabilization of a small, soluble, amyloid form of lysozyme which
has its own stability range and which can again unfold/refold many times before
an irreversible process, fibrillization, occurs. The tightly bound amyloid form
of the lysozyme molecule, identified by circular dichroism spectra and dynamic
light scattering, must be of very low energy since the unfolding process
absorbs almost three times the enthalpy of normal lysozyme unfolding.
alpha-lactalbumin shows similar behavior.

31
The categories of this paper are: ao-sci
33
The categories of this paper are: plasm-ph
15
The categories of this paper are: nucl-ex
22
The categories of this paper are: chao-dyn
19
The categories of this paper are: eess
30
The categories of this paper are: q-alg
25
The categories of this paper are: patt-sol
5
The categories of this paper are: gr-qc
37
The categories of this paper are: supr-con
12
The categories of this paper are: nucl-th
24
The categories of this paper are: dg-ga
14
The categories of this paper are: math-ph
29
The categories of this paper are: funct-an
20
The categories of this paper are: acc-phys
6
The categories of this paper are: astro-ph
35
The categories of this paper are: mtrl-th