Instruct: Identify the main category of Biorxiv papers based on the titles and abstracts
Query: Social learning about rewards: how information from others helps to adapt to changing environment Being a part of a social structure is key for survival and reproduction. Living with conspecifics boosts evolutionary fitness, by providing essential information about the environment. Nonetheless, studying neural mechanisms of social learning has not yet been established under laboratory conditions. To examine how socially passed information about the reward affects the behavior of individuals we used Eco-HAB, an automated system for tracing voluntary behavior of group-housed mice living under semi-naturalistic conditions. We show that a scent of a rewarded individual has profound effects on the conspecifics ability to find the reward in both familiar and novel environments. Importantly, the animals display clear and stable individual differences in social behavior. As a result, socially conveyed information has different effects on individual mice. Further, we show that disrupting neuronal plasticity in the prelimbic cortex with nanoparticles gradually releasing TIMP metallopeptidase inhibitor 1, disrupts animals social behavior and results in decreased ability to adapt to environmental changes. The experimental paradigm we developed can be further used to study neuronal mechanisms of social learning.
24
The categories of this paper are: cancer
25
The categories of this paper are: bioengineering
23
The categories of this paper are: immunology
10
The categories of this paper are: and
13
The categories of this paper are: animal
8
The categories of this paper are: genomics
27
The categories of this paper are: pathology
16
The categories of this paper are: microbiology
6
The categories of this paper are: plant
15
The categories of this paper are: developmental
20
The categories of this paper are: pharmacology
29
The categories of this paper are: education
19
The categories of this paper are: epidemiology
18
The categories of this paper are: systems
28
The categories of this paper are: communication
32
The categories of this paper are: zoology