Instruct: Identify the main and secondary category of Arxiv papers based on the titles and abstracts
Query: Investigation of HIV-1 Gag binding with RNAs and Lipids using Atomic
  Force Microscopy   Atomic Force Microscopy was utilized to study the morphology of Gag,
{\Psi}RNA, and their binding complexes with lipids in a solution environment
with 0.1{\AA} vertical and 1nm lateral resolution. TARpolyA RNA was used as a
RNA control. The lipid used was phospha-tidylinositol-(4,5)-bisphosphate
(PI(4,5)P2). The morphology of specific complexes Gag-{\Psi}RNA, Gag-TARpolyA
RNA, Gag-PI(4,5)P2 and PI(4,5)P2-{\Psi}RNA-Gag were studied. They were imaged
on either positively or negatively charged mica substrates depending on the net
charges carried. Gag and its complexes consist of monomers, dimers and
tetramers, which was confirmed by gel electrophoresis. The addition of specific
{\Psi}RNA to Gag is found to increase Gag multimerization. Non-specific
TARpolyA RNA was found not to lead to an increase in Gag multimerization. The
addition PI(4,5)P2 to Gag increases Gag multimerization, but to a lesser extent
than {\Psi}RNA. When both {\Psi}RNA and PI(4,5)P2 are present Gag undergoes
comformational changes and an even higher degree of multimerization.

14
The categories of this paper are: math-ph
1
The categories of this paper are: cs
23
The categories of this paper are: solv-int
0
The categories of this paper are: hep-ph
31
The categories of this paper are: ao-sci
24
The categories of this paper are: dg-ga
35
The categories of this paper are: mtrl-th
29
The categories of this paper are: funct-an
12
The categories of this paper are: nucl-th
25
The categories of this paper are: patt-sol
16
The categories of this paper are: stat
37
The categories of this paper are: supr-con
17
The categories of this paper are: q-fin
5
The categories of this paper are: gr-qc
7
The categories of this paper are: hep-th
8
The categories of this paper are: hep-ex