Instruct: Identify the main and secondary category of Arxiv papers based on the titles and abstracts
Query: A stochastic model for retinocollicular map development   We present a theoretical model for retinocollicular map development, which
can account for intriguing behaviors observed in gain-of-function experiments
in knock-in mice by Brown et al., including bifurcation in heterozygous
Isl2/EphA3 knock-ins. The model is based on known chemical labels, axonal
repulsion/competition, stochasticity and uses Markov chain description. Our
model suggests that the map in heterozygotes is single-valued in the temporal
region of retina due to reduced gradient of ephrin in the corresponding region
of SC. The remaining map is double-valued since the gradient of ephrin is high
there. We predict therefore that if gradient of ephrin is reduced by a genetic
manipulation, the single-valued region of the map should occupy a larger
portion of temporal retina, i.e. the point of transition between single- and
doulble-valued maps should move to a more nasal position in Isl2-EphA3
heterozygotes. We also discuss the importance of inhomogeneous EphA gradient
and mapping in Isl2/EphB knock-ins.

12
The categories of this paper are: nucl-th
24
The categories of this paper are: dg-ga
8
The categories of this paper are: hep-ex
13
The categories of this paper are: quant-ph
33
The categories of this paper are: plasm-ph
29
The categories of this paper are: funct-an
14
The categories of this paper are: math-ph
19
The categories of this paper are: eess
2
The categories of this paper are: math
17
The categories of this paper are: q-fin
7
The categories of this paper are: hep-th
27
The categories of this paper are: comp-gas
32
The categories of this paper are: atom-ph
36
The categories of this paper are: cmp-lg
23
The categories of this paper are: solv-int
37
The categories of this paper are: supr-con