Instruct: Identify the main and secondary category of Arxiv papers based on the titles and abstracts
Query: Towards personalized causal inference of medication response in mobile
  health: an instrumental variable approach for randomized trials with
  imperfect compliance   Mobile health studies can leverage longitudinal sensor data from smartphones
to guide the application of personalized medical interventions. In this paper,
we propose that adoption of an instrumental variable approach for randomized
trials with imperfect compliance provides a natural framework for personalized
causal inference of medication response in mobile health studies. Randomized
treatment suggestions can be easily delivered to the study participants via
electronic messages popping up on the smart-phone screen. Under quite general
assumptions we can identify the causal effect of the actual treatment on the
response in the presence of unobserved confounders. We implement a personalized
randomization test of the null hypothesis of no causal effect of treatment on
response, and evaluate its performance in a large scale simulation study
encompassing data generated from linear and non-linear time series models under
several simulation conditions. In particular, we evaluate the empirical power
of the proposed test under varying degrees of compliance between the suggested
and actual treatment adopted by the participant. Our investigations provide
encouraging results in terms of power and control of type I error rates.
Finally, we compare the proposed instrumental variable approach to a simple
intent-to-treat strategy, and develop randomization confidence intervals for
the causal effects.

32
The categories of this paper are: atom-ph
19
The categories of this paper are: eess
21
The categories of this paper are: adap-org
1
The categories of this paper are: cs
15
The categories of this paper are: nucl-ex
24
The categories of this paper are: dg-ga
9
The categories of this paper are: nlin
37
The categories of this paper are: supr-con
13
The categories of this paper are: quant-ph
10
The categories of this paper are: q-bio
35
The categories of this paper are: mtrl-th
3
The categories of this paper are: physics
12
The categories of this paper are: nucl-th
34
The categories of this paper are: chem-ph
17
The categories of this paper are: q-fin
18
The categories of this paper are: econ