Instruct: Identify the main and secondary category of Arxiv papers based on the titles and abstracts
Query: Optimal Allocation of Gold Standard Testing under Constrained
  Availability: Application to Assessment of HIV Treatment Failure   The World Health Organization (WHO) guidelines for monitoring the
effectiveness of HIV treatment in resource-limited settings (RLS) are mostly
based on clinical and immunological markers (e.g., CD4 cell counts). Recent
research indicates that the guidelines are inadequate and can result in high
error rates. Viral load (VL) is considered the "gold standard", yet its
widespread use is limited by cost and infrastructure. In this paper, we propose
a diagnostic algorithm that uses information from routinely-collected clinical
and immunological markers to guide a selective use of VL testing for diagnosing
HIV treatment failure, under the assumption that VL testing is available only
at a certain portion of patient visits. Our algorithm identifies the patient
subpopulation, such that the use of limited VL testing on them minimizes a
pre-defined risk (e.g., misdiagnosis error rate). Diagnostic properties of our
proposal algorithm are assessed by simulations. For illustration, data from the
Miriam Hospital Immunology Clinic (RI, USA) are analyzed.

20
The categories of this paper are: acc-phys
17
The categories of this paper are: q-fin
23
The categories of this paper are: solv-int
9
The categories of this paper are: nlin
28
The categories of this paper are: alg-geom
21
The categories of this paper are: adap-org
19
The categories of this paper are: eess
29
The categories of this paper are: funct-an
2
The categories of this paper are: math
11
The categories of this paper are: hep-lat
30
The categories of this paper are: q-alg
13
The categories of this paper are: quant-ph
0
The categories of this paper are: hep-ph
5
The categories of this paper are: gr-qc
18
The categories of this paper are: econ
32
The categories of this paper are: atom-ph