Instruct: Identify the main category of Biorxiv papers based on the titles and abstracts
Query: Point-localized and site-specific membrane potential optical recording by engineered single fluorescent nanodiscs Nanodisc technology was implemented as a platform for voltage nanosensors. A FRET-based voltage sensing scheme employing fluorescent nanodiscs and the hydrophobic ion dipicrylamine (DPA) was developed and utilized to optically record membrane potentials on the single nanodisc level. Ensemble- and single- nanosensor recordings were demonstrated for HEK293 cells and primary cortical neuron cells. Conjugation of nanodiscs to anti-GABA-A antibodies allowed for site specific membrane potential measurements from post synaptic sites.
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The categories of this paper are: scientific
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The categories of this paper are: bioengineering
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The categories of this paper are: zoology
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The categories of this paper are: physiology
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The categories of this paper are: biochemistry
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The categories of this paper are: pathology
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The categories of this paper are: education
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The categories of this paper are: genetics
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The categories of this paper are: behavior
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The categories of this paper are: genomics
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The categories of this paper are: epidemiology
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The categories of this paper are: pharmacology
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The categories of this paper are: cell
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The categories of this paper are: bioinformatics
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The categories of this paper are: microbiology
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The categories of this paper are: and