Instruct: Identify the main and secondary category of Arxiv papers based on the titles and abstracts
Query: On Multi-Armed Bandit Designs for Dose-Finding Clinical Trials   We study the problem of finding the optimal dosage in early stage clinical
trials through the multi-armed bandit lens. We advocate the use of the Thompson
Sampling principle, a flexible algorithm that can accommodate different types
of monotonicity assumptions on the toxicity and efficacy of the doses. For the
simplest version of Thompson Sampling, based on a uniform prior distribution
for each dose, we provide finite-time upper bounds on the number of sub-optimal
dose selections, which is unprecedented for dose-finding algorithms. Through a
large simulation study, we then show that variants of Thompson Sampling based
on more sophisticated prior distributions outperform state-of-the-art dose
identification algorithms in different types of dose-finding studies that occur
in phase I or phase I/II trials.

36
The categories of this paper are: cmp-lg
21
The categories of this paper are: adap-org
8
The categories of this paper are: hep-ex
7
The categories of this paper are: hep-th
17
The categories of this paper are: q-fin
26
The categories of this paper are: bayes-an
22
The categories of this paper are: chao-dyn
33
The categories of this paper are: plasm-ph
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The categories of this paper are: supr-con
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The categories of this paper are: comp-gas
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The categories of this paper are: math-ph
18
The categories of this paper are: econ
0
The categories of this paper are: hep-ph
5
The categories of this paper are: gr-qc
9
The categories of this paper are: nlin
13
The categories of this paper are: quant-ph