Instruct: Identify the main and secondary category of Arxiv papers based on the titles and abstracts
Query: Gender differences in appropriate shocks and mortality among patients
  with primary prophylactic implantable cardioverter-defibrillators: Systematic
  review and meta-analysis   BACKGROUND: Some but not all prior studies have shown that women receiving a
primary prophylactic implantable cardioverter defibrillator (ICD) have a lower
risk of death and appropriate shocks than men.
  PURPOSE: To evaluate the effect of gender on the risk of appropriate shock,
all-cause mortality and inappropriate shock in contemporary studies of patients
receiving a primary prophylactic ICD.
  DATA SOURCE: PubMed, LIVIVO, Cochrane CENTRAL between 2010 and 2016.
  STUDY SELECTION: Studies providing at least 1 gender-specific risk estimate
for the outcomes of interest.
  DATA EXTRACTION: Abstracts were screened independently for potentially
eligible studies for inclusion. Thereby each abstract was reviewed by at least
two authors.
  DATA SYNTHESIS: Out of 680 abstracts retained by our search strategy, 20
studies including 46'657 patients had gender-specific information on at least
one of the relevant endpoints. Mean age across the individual studies varied
between 58 and 69 years. The proportion of women enrolled ranged from 10% to
30%. Across 6 available studies, women had a significantly lower risk of first
appropriate shock compared with men (pooled multivariable adjusted hazard ratio
0.62 (95% CI [0.44; 0.88]). Across 14 studies reporting multivariable adjusted
gender-specific hazard ratio estimates for all-cause mortality, women had a
lower risk of death than men (pooled hazard ratio 0.75 (95% CI [0.66; 0.86]).
There was no statistically significant difference for the incidence of first
inappropriate shocks (3 studies, pooled hazard ratio 0.99 (95% CI [0.56;
1.73]).
  CONCLUSION: In this large contemporary meta-analysis, women had a
significantly lower risk of appropriate shocks and death than men, but a
similar risk of inappropriate shocks. These data may help to select patients
who benefit from primary prophylactic ICD implantation.

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The categories of this paper are: math-ph
6
The categories of this paper are: astro-ph
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The categories of this paper are: dg-ga
20
The categories of this paper are: acc-phys
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The categories of this paper are: chao-dyn
32
The categories of this paper are: atom-ph
5
The categories of this paper are: gr-qc
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The categories of this paper are: patt-sol
35
The categories of this paper are: mtrl-th
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The categories of this paper are: alg-geom
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The categories of this paper are: solv-int
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The categories of this paper are: q-fin
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The categories of this paper are: chem-ph
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The categories of this paper are: bayes-an
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The categories of this paper are: adap-org
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The categories of this paper are: comp-gas