Instruct: Identify the main and secondary category of Arxiv papers based on the titles and abstracts
Query: Quantitative Molecular Scaling Theory of Protein Amino Acid Sequences,
  Structure, and Functionality   Here we review the development of protein scaling theory, starting from
backgrounds in mathematics and statistical mechanics, and leading to biomedical
applications. Evolution has organized each protein family in different ways,
but scaling theory is both simple and effective in providing readily
transferable dynamical insights complementary for many proteins represented in
the 90 thousand static structures contained in the online Protein Data Base
(PDB). Scaling theory is a simplifying magic wand that enables one to search
the hundreds of millions of protein articles in the Web of Science, and
identify those proteins that present new cost-effective methods for early
detection and/or treatment of disease through individual protein sequences
(personalized medicine). Critical point theory is general, and recently it has
proved to be the most effective way of describing protein networks that have
evolved towards nearly perfect functionality in given environments
(self-organized criticality). Evolutionary patterns are governed by common
scaling principles, which can be quantified using scales that have been
developed bioinformatically by studying thousands of PDB structures. The most
effective scales involve either hydropathic globular sculpting interactions
averaged over length scales centered on membrane dimensions, or exposed beta
strand propensities associated with aggregative (strong) protein-protein
interactions.

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The categories of this paper are: atom-ph
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The categories of this paper are: math-ph
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The categories of this paper are: solv-int
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The categories of this paper are: ao-sci
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The categories of this paper are: hep-ex
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The categories of this paper are: supr-con
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The categories of this paper are: dg-ga
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The categories of this paper are: funct-an
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The categories of this paper are: physics
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The categories of this paper are: hep-lat
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The categories of this paper are: q-fin
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The categories of this paper are: cmp-lg
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The categories of this paper are: hep-ph
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The categories of this paper are: chao-dyn
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The categories of this paper are: hep-th
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The categories of this paper are: nlin