Instruct: Identify the main category of Medrxiv papers based on the titles and abstracts
Query: Direct comparison of venipuncture serum draws versus whole blood finger-stick specimens by anti-COVID-19 IgG/IgM rapid lateral flow immunoassay and ELISA. During the COVID-19 pandemic, manufacturers have developed several diagnostic test kits that include lateral flow immunoassays (LFIA) also known as rapid cassette testing. Rapid cassette testing provides qualitative test results indicating the presence or absence of IgG and IgM antibodies to determine COVID-19 (SARS-CoV-2) infection among individuals. Venipuncture blood draws have been the traditional and widely proposed sample collection method but is costly and not applicable to point-of-care testing (POC) and in remote settings. Whole blood finger-stick blood collections traditionally used by diabetics for glucose level testing is an ideal scenario, but raises concerns regarding the outcome of test results in regards to specificity and sensitivity. In this study we directly compare simultaneous collections of venipuncture serum (SST) blood draws and whole blood finger-sticks (n = 75) to detect human Anti-COVID-19 IgG and IgM antibodies using an EUA-approved lateral flow immunoassay, showing equal to enhanced performance characteristics for this specimen type.
35
The categories of this paper are: pediatrics
16
The categories of this paper are: immunology
4
The categories of this paper are: reproductive
15
The categories of this paper are: allergy
68
The categories of this paper are: surgery
13
The categories of this paper are: genetic
3
The categories of this paper are: sexual
19
The categories of this paper are: public
51
The categories of this paper are: education
26
The categories of this paper are: systems
6
The categories of this paper are: and
63
The categories of this paper are: pain
27
The categories of this paper are: quality
71
The categories of this paper are: ethics
33
The categories of this paper are: physical
69
The categories of this paper are: palliative