Instruct: Identify the main and secondary category of Arxiv papers based on the titles and abstracts
Query: Modelling brain based on canonical ensemble with functional MRI: A
  thermodynamic exploration on neural system   Objective. Modelling is an important way to study the working mechanism of
brain. While the characterization and understanding of brain are still
inadequate. This study tried to build a model of brain from the perspective of
thermodynamics at system level, which brought a new thinking to brain
modelling.
  Approach. Regarding brain regions as systems, voxels as particles, and
intensity of signals as energy of particles, the thermodynamic model of brain
was built based on canonical ensemble theory. Two pairs of activated regions
and two pairs of inactivated brain regions were selected for comparison in this
study, and the analysis on thermodynamic properties based on the model proposed
were performed. In addition, the thermodynamic properties were also extracted
as input features for the detection of Alzheimer's disease.
  Main results. The experiment results verified the assumption that the brain
also follows the thermodynamic laws. It demonstrated the feasibility and
rationality of brain thermodynamic modelling method proposed, indicating that
thermodynamic parameters could be applied to describe the state of neural
system. Meanwhile, the brain thermodynamic model achieved much better accuracy
in detection of Alzheimer's disease, suggesting the potential application of
thermodynamic model in auxiliary diagnosis.
  Significance. (1) Instead of applying some thermodynamic parameters to
analyze neural system, a brain model at system level was proposed from
perspective of thermodynamics for the first time in this study. (2) The study
discovered that the neural system also follows the laws of thermodynamics,
which leads to increased internal energy, increased free energy and decreased
entropy when system is activated. (3) The detection of neural disease was
demonstrated to be benefit from thermodynamic model, implying the immense
potential of thermodynamics in auxiliary diagnosis.

31
The categories of this paper are: ao-sci
37
The categories of this paper are: supr-con
30
The categories of this paper are: q-alg
29
The categories of this paper are: funct-an
33
The categories of this paper are: plasm-ph
19
The categories of this paper are: eess
25
The categories of this paper are: patt-sol
26
The categories of this paper are: bayes-an
24
The categories of this paper are: dg-ga
27
The categories of this paper are: comp-gas
36
The categories of this paper are: cmp-lg
6
The categories of this paper are: astro-ph
1
The categories of this paper are: cs
11
The categories of this paper are: hep-lat
14
The categories of this paper are: math-ph
5
The categories of this paper are: gr-qc