Instruct: Identify the main category of Medrxiv papers based on the titles and abstracts
Query: Neutralizing efficacy of vaccines against the SARS-CoV-2 Mu variant The rise of mutant strains of SARS-CoV-2 poses an additional problem to the existing pandemic of COVID-19. There are rising concerns about the Mu variant which can escape humoral immunity acquired from infections from previous strains or vaccines. We examined the neutralizing efficacy of the BNT162b2 mRNA vaccine against the Mu variant and report that the vaccine has 76% neutralizing effectiveness against the Mu compared to 96% with the original strain. We also show that Mu, similar to the Delta variant, causes cell-to-cell fusion which can be an additional factor for the variant to escape vaccine-mediated humoral immunity. Despite the rise in vaccine escape strains, the vaccine still possesses adequate ability to neutralize majority of the mutants.
57
The categories of this paper are: primary
60
The categories of this paper are: addiction
7
The categories of this paper are: emergency
46
The categories of this paper are: therapeutics
41
The categories of this paper are: nephrology
40
The categories of this paper are: geriatric
17
The categories of this paper are: informatics
8
The categories of this paper are: epidemiology
45
The categories of this paper are: pharmacology
16
The categories of this paper are: immunology
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The categories of this paper are: ethics
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The categories of this paper are: aids
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The categories of this paper are: rheumatology
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The categories of this paper are: hiv
20
The categories of this paper are: psychiatry
11
The categories of this paper are: policy