Instruct: Identify the main category of Medrxiv papers based on the titles and abstracts
Query: SARS-CoV-2 genomic surveillance enables the identification of Delta/Omicron co-infections in Argentina. Molecular surveillance of SARS-CoV-2 is crucial to early detect new variants and lineages. In addition, detection of coinfections with more than one SARS-CoV-2 lineage have been sporadically reported. In this work, surveillance of SARS-CoV-2 variants was performed on 2067 RNA samples (Ct>30) obtained during December 2021 and January 2022 from Cordoba province, Argentina, by real time RT-PCR specific for VOC/VOI relevant mutations (TaqMan SARS-CoV-2 Mutation Panel, Applied Biosystems). The following distribution of variants was obtained: Omicron (54.9%), Delta (44.2%) and Lambda (0.8%). Three samples (0.1%), obtained the last week of December, presented a profile compatible with a Delta/Omicron co-infection. One of them was sequenced by NGS-Illumina, obtaining reads for both VOCs. One of the studied patients presented severe symptoms, although he was not vaccinated and presented risk factors (older than 60 years, arterial hypertension). We describe for the first time in Argentina, the identification of cases of co-infection with two SARS-CoV-2 lineages, VOCs Delta and Omicron, during the third COVID-19 wave in the country (a high viral circulation period), when Delta and Omicron co-circulated. Our findings highlight the importance of continuing with molecular surveillance and co-detection studies of VOC/VOIs, in order to elucidate possible recombination events and the emergence of new variants.
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The categories of this paper are: orthopedics
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The categories of this paper are: hiv
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The categories of this paper are: improvement
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The categories of this paper are: environmental
35
The categories of this paper are: pediatrics
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The categories of this paper are: therapeutics
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The categories of this paper are: gynecology
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The categories of this paper are: palliative
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The categories of this paper are: genomic
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The categories of this paper are: education
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The categories of this paper are: otolaryngology
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The categories of this paper are: diseases
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The categories of this paper are: oral
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The categories of this paper are: pathology
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The categories of this paper are: research
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The categories of this paper are: informatics