Instruct: Identify the main and secondary category of Arxiv papers based on the titles and abstracts
Query: Scalable population-level modeling of biological cells incorporating
  mechanics and kinetics in continuous time   The processes taking place inside the living cell are now understood to the
point where predictive computational models can be used to gain detailed
understanding of important biological phenomena. A key challenge is to
extrapolate this detailed knowledge of the individual cell to be able to
explain at the population level how cells interact and respond with each other
and their environment. In particular, the goal is to understand how organisms
develop, maintain and repair functional tissues and organs.
  In this paper we propose a novel computational framework for modeling
populations of interacting cells. Our framework incorporates mechanistic,
constitutive descriptions of biomechanical properties of the cell population,
and uses a coarse graining approach to derive individual rate laws that enable
propagation of the population through time. Thanks to its multiscale nature,
the resulting simulation algorithm is extremely scalable and highly efficient.
As highlighted in our computational examples, the framework is also very
flexible and may straightforwardly be coupled with continuous-time descriptions
of biochemical signalling within, and between, individual cells.

19
The categories of this paper are: eess
37
The categories of this paper are: supr-con
1
The categories of this paper are: cs
24
The categories of this paper are: dg-ga
18
The categories of this paper are: econ
11
The categories of this paper are: hep-lat
6
The categories of this paper are: astro-ph
5
The categories of this paper are: gr-qc
2
The categories of this paper are: math
25
The categories of this paper are: patt-sol
0
The categories of this paper are: hep-ph
16
The categories of this paper are: stat
26
The categories of this paper are: bayes-an
14
The categories of this paper are: math-ph
32
The categories of this paper are: atom-ph
31
The categories of this paper are: ao-sci