Instruct: Identify the main and secondary category of Arxiv papers based on the titles and abstracts
Query: Quantitative Human Paleogenetics: what can ancient DNA tell us about
  complex trait evolution?   Genetic association data from national biobanks and large-scale association
studies have provided new prospects for understanding the genetic evolution of
complex traits and diseases in humans. In turn, genomes from ancient human
archaeological remains are now easier than ever to obtain, and provide a direct
window into changes in frequencies of trait-associated alleles in the past.
This has generated a new wave of studies aiming to analyse the genetic
component of traits in historic and prehistoric times using ancient DNA, and to
determine whether any such traits were subject to natural selection. In humans,
however, issues about the portability and robustness of complex trait inference
across different populations are particularly concerning when predictions are
extended to individuals that died thousands of years ago, and for which little,
if any, phenotypic validation is possible. In this review, we discuss the
advantages of incorporating ancient genomes into studies of trait-associated
variants, the need for models that can better accommodate ancient genomes into
quantitative genetic frameworks, and the existing limits to inferences about
complex trait evolution, particularly with respect to past populations.

28
The categories of this paper are: alg-geom
37
The categories of this paper are: supr-con
9
The categories of this paper are: nlin
22
The categories of this paper are: chao-dyn
27
The categories of this paper are: comp-gas
3
The categories of this paper are: physics
23
The categories of this paper are: solv-int
20
The categories of this paper are: acc-phys
0
The categories of this paper are: hep-ph
34
The categories of this paper are: chem-ph
29
The categories of this paper are: funct-an
16
The categories of this paper are: stat
11
The categories of this paper are: hep-lat
8
The categories of this paper are: hep-ex
26
The categories of this paper are: bayes-an
5
The categories of this paper are: gr-qc