How effective are these as they are NOT in an enterically -coated capsule?I have always given capsules because I read that this insured the probiotics' survival past the stomach acid, and into the intestine (which is where they are most needed).Do you all feel that this powder form is truly effective? -- it certainly would make it MUCH easier for me to dose to my furbaby, that is for sure. :) How effective are these as they are NOT in an enterically -coated capsule?I have always given capsules because I read that this insured the probiotics' survival past the stomach acid, and... » Read More How effective are these as they are NOT in an enterically -coated capsule?I have always given capsules because I read that this insured the probiotics' survival past the stomach acid, and into the intestine (which is where they are most needed).Do you all feel that this powder form is truly effective? -- it certainly would make it MUCH easier for me to dose to my furbaby, that is for sure. :) « Show Less
1483804
This powder is WONDERFUL! My little yorkie 14 years old and 3 pounds was sickened last spring with salmonella from his premium pet food, the vet not knowing at first what made him sick, gave him a very strong antiboitic that gave him diarrhea for 6 months!!! The only thing that helped was a little sprinkle of Mercola powder over his food - he's been fine since! (started last September 2013). My older dog, a poodle, 17 years old, has been constipated for years! I decided to sprinkle some of this Mercola powder over her food and AMAZING it works for that too!! She is able to go easily morning and evening. Thank GOD for Mercola powder! This powder is WONDERFUL! My little yorkie 14 years old and 3 pounds was sickened last spring with salmonella from his premium pet food, the vet not knowing at first what made him sick, gave him a very strong antiboitic that gave him diarrhea for 6 months!!! The only thing that helped was a little sprinkle of Mercola powder over his food - he's been fine since! (started last September 2013). My older dog, a poodle, 17 years old, has been constipated for years! I decided to sprinkle some of this Mercola powder over her food and AMAZING it works for that too!! She is able to go easily morning... » Read More This powder is WONDERFUL! My little yorkie 14 years old and 3 pounds was sickened last spring with salmonella from his premium pet food, the vet not knowing at first what made him sick, gave him a very strong antiboitic that gave him diarrhea for 6 months!!! The only thing that helped was a little sprinkle of Mercola powder over his food - he's been fine since! (started last September 2013). My older dog, a poodle, 17 years old, has been constipated for years! I decided to sprinkle some of this Mercola powder over her food and AMAZING it works for that too!! She is able to go easily morning and evening. Thank GOD for Mercola powder! « Show Less
1483805
I have had my two 1yr collies on these probiotics since bringing them home without any problems what so ever. No gastritis no diarrhea or any other GI problems. For sure easy to mix in with their wet food. Hope this helps and good luck.
1483806
My IBS-prone kitty has been on this for nearly 2 years, and although what you are saying sounds reasonable, the incidences of that problem have been extremely minimized. I also put the Mercola digestive enzymes in her food. The probiotic is probably the main reason for her improved health, but I believe both of these products are very effective based on my experience. Just wish the probiotic didn't cost so much! But both products last a while. Hope this helps.
1483807
can't say it was particularly effective for my cat's IBD but I don't know if it would have made a difference if it had been coated capsules.
19615
Dear Madster07, I really think that is a question for a veterinarian as I know dogs have different bacteria in their much shorter length intestines. It may be ok but it also might depend on the weight of the dog as well. Years ago we had pet Dwarf Lop-Eared rabbits. Our favorite one developed terrible seizures at about age 7. I researched and found that Melatonin 3mg daily helped control seizures in children. So I bought a good 3mg brand that was sublingual that had a pleasant fruit taste to it. Then I cut the tablets in 4 quarters as figured the bunny was at least a quarter the weight of a small child. I gave it one every day over the rest of its life and rarely had any seizures again. But since these are capsules and have to be taken on an empty stomach, I don't know how you would work that out. Good luck, hope you find relief for your pet.
1728977
Master Supplements has been GREAT, I have ordered from them many times from Amazon. I have ordered Probiotics online for years, many come completely un-insulated. It arrives well wrapped/insulated in bubble wrap. I have found this to be more than adequate. It may appear a bit more expensive, however.... There are other less expensive suppliers, even with more elaborate insulation, but I don't want my package in transit for MANY days longer. With those less expensive suppliers, you can pay for faster shipping, but then you're back up to 'expensive'... I go with Amazon/Master Supplements and be done with it! Master Supplements has been GREAT, I have ordered from them many times from Amazon. I have ordered Probiotics online for years, many come completely un-insulated. It arrives well wrapped/insulated in bubble wrap. I have found this to be more than adequate. It may appear a bit more expensive, however.... There are other less expensive suppliers, even with more elaborate insulation, but I don't want my package in transit for MANY days longer. With those less expensive suppliers, you can pay for faster shipping, but then you're back up to 'expensive'... I go with Amazon/Master Supplements and... » Read More Master Supplements has been GREAT, I have ordered from them many times from Amazon. I have ordered Probiotics online for years, many come completely un-insulated. It arrives well wrapped/insulated in bubble wrap. I have found this to be more than adequate. It may appear a bit more expensive, however.... There are other less expensive suppliers, even with more elaborate insulation, but I don't want my package in transit for MANY days longer. With those less expensive suppliers, you can pay for faster shipping, but then you're back up to 'expensive'... I go with Amazon/Master Supplements and be done with it! « Show Less
506455
I ordered it to help my bowel activity. I didn't follow the directions exactly, since I wasn't aiming for a cleanse, but rather a ju,p start. The probiotics worked for me, as I chose to add it (in less than the recommended dose) to protein powder that I was mixing with other ingredients to a drink. Hopes this helps.
553277
They are capsules, not chewable. I open them up and mix it with my dogs food. Only Natural Pet has a good chewable probiotic you might want to try, go to Onlynaturalpet.com
1183591
Probiotic miracle works great for my diabetic fur baby. I give him less than the suggested amount or it gives him real soft poops. He has not had a UTI since being DX with diabetes and that was 2 years ago. It says on the website it is made in the USA. I like it because it doesn't have many inactive ingredients (fillers) in it. It doesn't upset his stomach either. I live in Florida so I do keep it in the refrigerator. Go to Nusentia.com for further answers. There you can contact them. I tried the Mercola probiotic and my diabetic baby did awful on it. He got a stomachache and started to eat grass to vomit. To many fillers in the Mercola probiotic. I also give probiotic miracle to my other fur baby. But beware you give to much and it will give them the poops because it does have inulin in it. I give my 25 pound dog (diabetic) a little less than an 1/8 of a tsp. 2x a day and my 7 pound dog 1/2 of an 1/8 of a tsp. in each bowl of food. I home cook for my guys, they get no dog food. I also supplement with Nupro, omega 3 oil, vitamin E, and brewers yeast with garlic. I put no poison on my guys either and no vaccines ever again for my guys. Over vaccinating is killing our fur babies. Good luck!!!
1690508
I have had no digestive problems with them. The manufacturer states "PB8 PRO-Biotic Acidophilus contains specially selected bacteria that are protected from destructive stomach acids by a special coating applied during its unique production method. The capsules need no refrigeration and contain eight strains of friendly bacteria
1559893
Yes, it is more than true. With a standard capsule containing 12 billion CFU, approximately 4% of the beneficial organisms will make it to your GI tract alive (due to things like shelf stability and the effects of stomach acids) which means the benefit delivered to you is roughly 480 million. With our patented technology, PRO-15 delivers as many as 15 times, or more, the number of live, viable probiotic organisms past simulated stomach acids than (plain/standard) capsules as repeatedly demonstrated through in vitro lab testing. Effectively, 60% of the 5 billion organisms in PRO-15 will make it to your gut alive. This means you'll get 3 billion CFU as opposed to the modest 40 million in the example above.
999471
they absolutely do not pack w/ice. not only that, but i had a quality assurance issue. my bottle contained an empty capsule & a crimped half of another capsule. the company said it was no big deal. i paid for the quantity on the container but received less. i'm dissatisfied w/this company. i have switched to garden of life RAW probiotics. they contain much higher amounts of bacteria but they are also NOT shipped on ice. good luck.
1112551
In my opinion, the "billion number" is probably adequate on any product if you have no gastro problems. If you do, that number is the number of live bacteria and should be a little higher. The real test of a probiotic is how many "strains" it covers (should be ten or more), and what the delivery system is. If it is an enteric or time release capsule, then it will get down to the gut where you need it, and not release in the stomach from your gastic acids.
515864
It is a granular release capsule. The capsule is smaller than most! I imagine all probiotics are granular release also. The product is reliable and really dependable!
1288312
I think this should be a question for the manufacturer. It seems too much like medical advice to say whether to take a supplement without it's "sealed container." I have started taking mine every other day because I do notice a 'fishy" burp occasionally. Otherwise I like them. I would look for a smaller pill for your son, even if he has to take more than one to get the necessary amount.
1082740
I'm taking them and they have no noticable effect on me at all. I didn't try any skin application,- if your "directly" means "orally". - Probably if you try skin application, - it probably could have some healing effect though I doubt it unless if you put it on your skin with something that really works. Though they should be effective,- but no effect on me means that powder inside of these capsules is too much processed,- that's my opinion. I don't think that there's any difference if you take them on empty stomach or after food because I tried both ways and just even without placebo effect. though if you really believe then they could be effective. God bless You. I'm taking them and they have no noticable effect on me at all. I didn't try any skin application,- if your "directly" means "orally". - Probably if you try skin application, - it probably could have some healing effect though I doubt it unless if you put it on your skin with something that really works. Though they should be effective,- but no effect on me means that powder inside of these capsules is too much processed,- that's my opinion. I don't think that there's any difference if you take them on empty stomach or after food because I tried both ways and... » Read More I'm taking them and they have no noticable effect on me at all. I didn't try any skin application,- if your "directly" means "orally". - Probably if you try skin application, - it probably could have some healing effect though I doubt it unless if you put it on your skin with something that really works. Though they should be effective,- but no effect on me means that powder inside of these capsules is too much processed,- that's my opinion. I don't think that there's any difference if you take them on empty stomach or after food because I tried both ways and just even without placebo effect. though if you really believe then they could be effective. God bless You. « Show Less
1031645
John, The nice thing about the Primal Defense is made so the Probiotics are viable without refrigeration. It works really well and I have 2 chronic illnesses. This is the only product(s) that have worked for me and I honestly can say if it's worked for me there's a high probability it'll work for anyone. I also highly recommend reading the book Patient Heal Thyself from the holistic doctor who produced these products. I hope this helps.
254936
If it were time released, it would say on the bottle...I really like this product, and it makes a huge difference when I take them. Very good for regulating the system, and stopping you from bloating.It is hard to find this many strains 10 strain and this many 50 billion in one capsuleOne per day works well for me, especially in combination with a fiber supplement or prebiotics.Now trusted professionals are recommending 100 billion per day. It is very important to have at least 10 strains and up to 14 per capsule. Capsules are best, I do not like tablets, especially in this supplement. I wish Amazon would keep more in stock. If it were time released, it would say on the bottle...I really like this product, and it makes a huge difference when I take them. Very good for regulating the system, and stopping you from bloating.It is hard to find this many strains 10 strain and this many 50 billion in one capsuleOne per day works well for me, especially in combination with a fiber supplement or prebiotics.Now trusted professionals are recommending 100 billion per day. It is very important to have at least 10 strains and up to 14 per capsule. Capsules are best, I do not like tablets,... » Read More If it were time released, it would say on the bottle...I really like this product, and it makes a huge difference when I take them. Very good for regulating the system, and stopping you from bloating.It is hard to find this many strains 10 strain and this many 50 billion in one capsuleOne per day works well for me, especially in combination with a fiber supplement or prebiotics.Now trusted professionals are recommending 100 billion per day. It is very important to have at least 10 strains and up to 14 per capsule. Capsules are best, I do not like tablets, especially in this supplement. I wish Amazon would keep more in stock. « Show Less
2060277
I have been using Nexabiotic for some time now and never have I refrigerated this product. I live in a very hot climate and I have had this delivered to me by mail and the bottle was so overly warm that I thought they live culture was going to be dead. It turns out that the company who makes these also flash freezes them and they held up just like they said they would. I have no worries or fears about these probiotics from Nexabiotic. I have to say that when I first started taking them, I not only had digestive issue but I also had recurring feminine itch, within the next 30 days I not only was eating normal again, but the female problem also cleared and I have not had any issues since then, and that was at the early part of this year. You can relax about the refrigeration issue and trust this product and the company behind them. Sincerely; Patricia Woodard
1816562
I take Digestive Advantage gas defense probiotic. For me it stop the gas in the intestine. I love this product.