Instruct: Classify Amazon reviews into positive or negative sentiment
Query: Disappointing

After such classics as "In an Antique Land" and "The Shadowlines," Ghosh's latest book is rather a let down, much like "Circle of Reason." In "The Calcutta Chromosome," the characters are not well developed at all, and they all seems so contradictory, especially Dr. Murugan, who carries much of the burden of this book. Part science, part science fiction, part mystery, the story becomes less compelling when doused heavily with the technobabble of science and computers (the latter is very unrealistic, even for a futuristic fantasy.) Simply put, it detracts from a potentially interesting story. Even the concept of the Chromosome and it's omnipotent possiblities is not developed enough to make the title a compelling one.