what meds are sglt2 inhibitors?
234898
Sodium-glucose Cotransporter-2 (SGLT2) Inhibitors. SGLT2 inhibitors are a class of prescription medicines that are FDA-approved for use with diet and exercise to lower blood sugar in adults with type 2 diabetes. Medicines in the SGLT2 inhibitor class include canagliflozin, dapagliflozin, and empagliflozin.
381304
['Metformin (Glucophage, Glumetza, others). Generally, metformin is the first medication prescribed for type 2 diabetes. ... ', 'Sulfonylureas. ... ', 'Meglitinides. ... ', 'Thiazolidinediones. ... ', 'DPP-4 inhibitors. ... ', 'GLP-1 receptor agonists. ... ', 'SGLT2 inhibitors. ... ', 'Insulin.']
737252
['omeprazole (Prilosec, Prilosec OTC, Zegerid)', 'lansoprazole (Prevacid)', 'pantoprazole (Protonix)', 'rabeprazole (Aciphex)', 'esomeprazole (Nexium)', 'dexlansoprazole (Dexilant)']
1256877
Steglatro is the fourth SGLT-2 to be approved in the US, joining Jardiance (empagliflozin), Invokana (canagliflozin), and Farxiga (dapagliflozin).
678951
['Fiasp and NovoRapid® (insulin aspart)', 'Humalog® (insulin lispro)', 'Apidra® (insulin glulisine).']
278367
SGLT2 inhibitors work by preventing the kidneys from reabsorbing glucose back into the blood. This allows the kidneys to lower blood glucose levels and the excess glucose in the blood is removed from the body via urine.
178736
['Mylanta.', 'Maalox.', 'Tums.', 'Rolaids.', 'Gas-X/Simethiconem, Tagamet,', 'Pepcid, Prilosec, Prevacid (If no relief from Tums or Rolaids)']
682430
['Amphetamine (Adzenys XR-ODT, Dyanavel XR)', 'Dexmethylphenidate (Focalin XR)', 'Dextroamphetamine (Adderall XR)', 'Lisdexamfetamine (Vyvanse)', 'Methylphenidate (Concerta, Daytrana, Jornay PM, Metadate CD, Quillivant XR, Quillichew ER, Ritalin LA)']
375085
['Bydureon (Exenatide) – taken once weekly.', 'Byetta (Exenatide) – taken twice daily.', 'Lyxumia (lixisenatide) – taken once daily.', 'Trulicity (Dulaglutide) – taken once weekly.', 'Victoza (Liraglutide) – taken once daily.']
641127
Conclusions: SGLT2 inhibitor and GLP-1 agonist combination treatment improved glycemic control, reduced body weight, and decreased SBP without an increase in total AEs or genital and urinary infections in patients with T2DM. However, the risk of hypoglycemia should be carefully monitored in future clinical trials.
355445
['DPP-4 inhibitors are a class of prescription medicines that are used with diet and exercise to control high blood sugar in adults with type 2 diabetes.', 'Medicines in the DPP-4 inhibitor class include sitagliptin, saxagliptin, linagliptin, and alogliptin.']
777806
['Amlodipine (Norvasc)', 'Diltiazem (Cardizem, Tiazac, others)', 'Felodipine.', 'Isradipine.', 'Nicardipine.', 'Nifedipine (Adalat CC, Procardia)', 'Nisoldipine (Sular)', 'Verapamil (Calan, Verelan)']
584880
SGLT2 inhibition lowers the renal threshold for glucose excretion, resulting in renal glycosuria, a shift in substrate utilisation from carbohydrate to fat oxidation and hyperglucagonaemia; this poses a theoretical risk for ketoacidosis (including euglycaemic ketoacidosis) in the presence of other precipitating factors ...
242354
['Chlorthalidone (Hygroton)', 'Chlorothiazide (Diuril)', 'Hydrochlorothiazide or HCTZ (Esidrix, Hydrodiuril, Microzide)', 'Indapamide (Lozol)', 'Metolazone (Mykrox, Zaroxolyn)']
222801
['Tums.', 'Rolaids.', 'Mylanta.', 'Zantac.', 'Tagamet, Pepcid, Prilosec, Prevacid (If no relief from Tums or Rolaids)']
1362526
Their oral dosage form and long history of clinical experience make them a mainstay in the treatment of T2DM. Three sulfonylureas are available in the United States—glimepiride, glipizide, and glyburide—and all 3 are roughly clinically interchangeable in terms of hemoglobin A1c (HbA1c) lowering.
86536
['Angiotensin-converting enzyme (ACE) inhibitors.', 'Calcium channel blockers.', 'Angiotensin II receptor blockers.']