can nsaids cause reye's syndrome?
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Reye's Syndrome: Why Aspirin and Children Don't Mix Acetaminophen, ibuprofen, and aspirin are easily available and generally safe in small doses. Most of these are safe for children, as well. However, aspirin is an important exception. Aspirin is associated with a risk of Reye's syndrome in children.
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Though the medication can still be sold and used, a black box warning alerts doctors and patients to potentially dangerous problems. Nonsteroidal anti-inflammatory drugs (NSAIDs), such as nabumetone, may increase risk of blood clots, heart attack, or stroke.
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NSAIDs include ibuprofen (found in Advil and Motrin), naproxen (found in Aleve), celecoxib (aka Celebrex), and aspirin. They don't include acetominophen or multiple-symptom medications that contain it, like DayQuil, Midol, and Excedrin. Unlike acetaminophen, NSAIDs reduce inflammation to reduce joint and muscle pain.
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NSAIDS may also cause a non specific type of colitis and small intestinal inflammation with associated complications of chronic blood or protein loss [8].
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An overdose of these medications may cause stomach upset, abdominal pain, and vomiting. Larger amounts of NSAIDs can injure the kidneys. Also, they may cause ulcers, bleeding, seizures, and coma.
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An allergy or hypersensitivity to both ASA and NSAIDs may cause any of the following: hives, itching, swelling, shortness of breath, nasal congestion, wheezing, feeling faint or even passing out. When these reactions are severe, it is called anaphylaxis.
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NSAIDs such as ibuprofen may cause ulcers, bleeding, or holes in the stomach or intestine. These problems may develop at any time during treatment, may happen without warning symptoms, and may cause death.
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Even intravenous or intramuscular administration of aspirin or NSAIDs such as ketorolac can cause gastric or duodenal ulcers in animals and humans [3-6].
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Research has discovered that the risk of gastrointestinal (GI) side effects such as stomach ulcers and stomach bleeding increases the longer somebody takes NSAIDS. Aleve is more likely than Advil to cause GI side effects because it is longer acting.
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Doing so may increase your risk of a heart attack and stroke. Naproxen may cause ulcers and bleeding in your stomach and intestines. This can happen at any time during treatment and may occur without symptoms. This effect can result in death.
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Serious, but rare, side effects of prescription NSAIDs may include: Allergic reaction. This could include difficulty breathing, hives, and swelling of the lips, tongue, or face. Muscle cramps, numbness, or tingling.
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These medications should only be used under a doctor's care by patients with kidney disease, heart disease, high blood pressure or liver disease or by people who are over 65 or who take diuretic medications. NSAIDs may cause an increased risk of sudden kidney failure and even progressive kidney damage.
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Nonsteroidal anti-inflammatory drugs, or NSAIDs (pronounced en-saids), are the most prescribed medications for treating conditions such as arthritis. Most people are familiar with over-the-counter, nonprescription NSAIDs, such as aspirin and ibuprofen. NSAIDs are more than just pain relievers.
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Abstract. Aspirin and nonaspirin nonsteroidal antiinflammatory drugs (NSAIDs) inhibit platelet cyclooxygenase, thereby blocking the formation of thromboxane A2. These drugs produce a systemic bleeding tendency by impairing thromboxane-dependent platelet aggregation and consequently prolonging the bleeding time.
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Aspirin and nonsteroidal anti-inflammatory drugs (NSAIDs) like naproxen (Aleve) and ibuprofen (Motrin, Advil) are known to cause ringing in the ears and hearing loss when used at high doses and/or for long periods of time.
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Abstract. Helicobacter pylori infection and the use of non-steroidal anti-inflammatory drugs (NSAIDs) can each result in gastroduodenal ulcers and ulcer complications. Recent studies have suggested that there is an interaction between the two causes such that elimination of H.
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Don't combine aspirin with related pain relievers. Medications such as ibuprofen (Advil and generic) or naproxen (Aleve and generic) are chemically related to aspirin, so taken together they multiply the risk of stomach problems.