what are non selective cox inhibitors?
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Non-selective NSAIDs are drugs that inhibit both types of the COX enzyme and thus are associated with an increased risk of gastric ulceration, presumed to be both through the reduction in gastric protection that is provided by prostaglandins, as well as direct irritation of the gastric lining.
507063
Background. Nonsteroidal anti-inflammatory drugs (NSAIDs) have been associated with clinically significant decreases in haemoglobin dependent and independent of acute bleeding events.
1417920
Aspirin inhibits COX-1 (cyclooxygenase-1). Its effect on COX-2 is more delicate: it "turns off" COX-2's production of prostaglandins but "switches on" the enzyme's ability to produce novel protective lipid mediators. Aspirin is a widely used non-steroidal anti-inflammatory drug (NSAID).
530313
Nonsteroidal anti-inflammatory drugs, or NSAIDs (pronounced en-saids), are the most prescribed medications for treating conditions such as arthritis. Most people are familiar with over-the-counter, nonprescription NSAIDs, such as aspirin and ibuprofen. NSAIDs are more than just pain relievers.
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['aspirin.', 'celecoxib (Celebrex)', 'diclofenac (Cambia, Cataflam, Voltaren-XR, Zipsor, Zorvolex)', 'diflunisal (Dolobid - discontinued brand)', 'etodolac (Lodine - discontinued brand)', 'ibuprofen (Motrin, Advil)', 'indomethacin (Indocin)']
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Nimesulide is a nonsteroidal anti-inflammatory drug (NSAID) with pain medication and fever reducing properties. Its approved indications are the treatment of acute pain, the symptomatic treatment of osteoarthritis, and primary dysmenorrhoea in adolescents and adults above 12 years old.
1157842
COX-2 inhibitors are NSAIDs that selectively block the COX-2 enzyme and not the COX-1 enzyme. Blocking this enzyme impedes the production of prostaglandins by the COX-2 which is more often the cause the pain and swelling of inflammation and other painful conditions.
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Abstract. Meloxicam is a new non-steroidal anti-inflammatory drug (NSAID) that selectively inhibits the inducible isoform of the cyclo-oxygenase (COX)-2 enzyme.
1250618
What are COX-2 Inhibitors (e.g. Vioxx, Celebrex and Bextra)? The main brands of COX-2 inhibitor drugs currently on the market are Celebrex and Bextra (since the Vioxx recall). COX-2 inhibitors are a newer type of NSAID that block the COX-2 enzyme at the site of inflammation.
1447373
['81MG LOW DOSE ASPIRIN. [01:11]', 'HUMANOFORT. [04:49]', 'LONGVIDA CURCUMIN. [06:10]', 'DIGESTIVE ENZYMES/PROBIOTICS. [07:30]', "OMEGA 3'S. [10:04]"]
150032
Nonsteroidal anti-inflammatory drugs (NSAIDs). NSAIDs reduce both pain and inflammation. Over-the-counter NSAIDs include ibuprofen (Advil, Motrin IB, others) and naproxen (Aleve). Some types of NSAIDs are available only by prescription.
585507
NSAIDs, or non-steroidal anti-inflammatory drugs are a class of drugs that work to decrease blood levels of prostaglandins, chemicals that promote inflammation and pain.
1158351
COX-2 inhibitor. COX-2 inhibitors are a type of nonsteroidal anti-inflammatory drug (NSAID) that directly targets cyclooxygenase-2, COX-2, an enzyme responsible for inflammation and pain.
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a nonsteroidal antiinflammatory drug used as an analgesic and antipyretic and for symptomatic relief of dysmenorrhea, vascular headaches, rheumatoid arthritis, osteoarthritis, and other rheumatic and nonrheumatic inflammatory disorders.
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['Aspirin (Bufferin, Bayer)', 'Celecoxib (Celebrex)', 'Diclofenac (Cataflam, Voltaren)', 'Diflunisal (Dolobid)', 'Etodolac (Lodine)', 'Fenoprofen (Nalfon)', 'Flurbiprofen (Ansaid)', 'Ibuprofen (Advil, Motrin)']
409189
Two drugs that are claimed to be highly selective or specific in their ability to inhibit COX-2 while having little or no COX-1 affinity are rofecoxib and celecoxib. These selective NSAIDs reduce the pain and inflammation associated with rheumatoid arthritis and osteoarthritis.
571454
Ibuprofen and naproxen are both nonsteroidal anti-inflammatory drugs (NSAIDs). You may know them by their most popular brand names: Advil (ibuprofen) and Aleve (naproxen). These drugs are alike in many ways, so you may even wonder if it really matters which one you choose.