what is the average weight gain on zoloft?
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Experts say that for up to 25% of people, most antidepressant medications -- including the popular SSRI (selective serotonin reuptake inhibitor) drugs like Lexapro, Paxil, Prozac, and Zoloft -- can cause a weight gain of 10 pounds or more.
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Antidepressants that are less likely to cause weight gain escitalopram (Lexapro, Cipralex), an SSRI. duloxetine (Cymbalta), a serotonin-norepinephrine reuptake inhibitor (SNRI), may cause modest weight gain with long-term use. bupropion (Wellbutrin, Forfivo, and Aplenzin), an atypical antidepressant.
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Mirtazapine is associated with weight gain both in the short- and long-term. Patients taking mirtazapine often report a voracious appetite, with intense cravings for carbohydrates. One meta-analysis examining 4 studies demonstrated that the majority of weight gain took place during the first 4 weeks of treatment.
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While some people gain weight after starting an antidepressant, the antidepressant isn't always a direct cause. Many factors can contribute to weight gain during antidepressant therapy. For example: Overeating or inactivity as a result of depression can cause weight gain.
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Substantial weight gain is a common side effect of most antidepressant medication, and for many people, the weight is lost once the medication is no longer being taken. However, one antidepressant, bupropion (also known as Wellbutrin) seems to have the opposite effect.
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Of the newer selective serotonin reuptake inhibitors (SSRIs for short), paroxetine (brand name Paxil) has more anticholinergic activity and so causes more weight gain. Another relatively new antidepressant, mirtazapine (brand name Remeron), blocks the histamine receptor and is associated with significant weight gain.
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Prozac and Weight Gain Weight gain is a side effect of many antidepressants, including Prozac. A study published in 2014 in the journal JAMA Psychiatry found that people taking Prozac and other SSRIs gained one to two pounds over the course of a year; weight gain varied, depending on the SSRI used.
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Patients taking VRAYLAR experienced changes in blood sugar and cholesterol similar to those who took a placebo. In 6-week and 8-week bipolar depression studies, patients who took VRAYLAR experienced an average weight gain of 1.2 pounds, compared to those on placebo who lost 0.2 pounds.
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While experts may not be certain about why antidepressants cause weight gain, they do know that switching drugs may make a difference. Some antidepressants may be less likely to affect weight. Effexor and Serzone generally do not cause weight gain, while Wellbutrin can cause weight loss.
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If you lose weight, tell your doctor. Although sertraline is generally associated with weight gain, it can also cause short-term weight loss by affecting your appetite. This is most common during the first weeks of treatment.
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['escitalopram (Lexapro, Cipralex), an SSRI.', 'duloxetine (Cymbalta), a serotonin-norepinephrine reuptake inhibitor (SNRI), may cause modest weight gain with long-term use.', 'bupropion (Wellbutrin, Forfivo, and Aplenzin), an atypical antidepressant.']
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The majority (89.4%) reported that antidepressants had improved their depression although 30% reported moderate-to-severe depression on antidepressants. Common adverse effects included withdrawal effects (73.5%), sexual problems (71.8%), and weight gain (65.3%).
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According to medical studies, it's been reported that patients who take lithium experience an average of 10 to 26 pounds of weight gain.
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Peak effects are seen within 4.5 to 8 hours. Some reduction in symptoms of depression or anxiety may be seen within the first week of taking Zoloft; however, it may take up to six weeks for the full effects of Zoloft are seen.
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Compared to citalopram, the weight gain linked to other antidepressants was small. Bupropion was associated with the least amount of weight gain, close to none. Two others that also appeared to have less weight gain were amitriptyline and nortriptyline. Amitriptyline and nortriptyline are older drugs.
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What doses are available for Zoloft? Fluoxetine is available as capsules: 10, 20 and 40 mg. Capsules (delayed release): 90 mg. Tablets: 10, 20 and 60 mg.
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Weight gain is a possible side effect of nearly all antidepressants. However, each person responds to antidepressants differently. Some people gain weight when taking a certain antidepressant, while others don't.