can sickle cell cause priapism?
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Recurrent or stuttering priapism, a form of ischemic priapism, is an uncommon condition. It's more common in males who have an inherited disorder characterized by abnormally shaped red blood cells (sickle cell anemia). Sickle cells can block the blood vessels in the penis.
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In sickle cell anemia, the red blood are shaped like sickles or crescent moons. These rigid, sticky cells can get stuck in small blood vessels, which can slow or block blood flow and oxygen to parts of the body.
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People with sickle cell anemia can develop high blood pressure in their lungs. This complication usually affects adults. Shortness of breath and fatigue are common symptoms of this condition, which can be fatal. Organ damage.
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Additionally, in individuals with the genetic defect, the painful sickle cell crisis can be precipitated by certain medical and environmental factors including infection, bleeding, exposure to cold weather, leg ulcers, and blockage of the blood vessels.
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When red blood cells sickle, they break down prematurely, which can lead to anemia. Anemia can cause shortness of breath, fatigue, and delayed growth and development in children. The rapid breakdown of red blood cells may also cause yellowing of the eyes and skin, which are signs of jaundice.
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The leading causes of death in sickle cell diseases (SCD) are infection, pain episodes, acute chest syndrome and stroke [1, 2].
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['Anemia. Sickle cells break apart easily and die, leaving you with too few red blood cells. ... ', 'Episodes of pain. ... ', 'Swelling of hands and feet. ... ', 'Frequent infections. ... ', 'Delayed growth or puberty. ... ', 'Vision problems.']
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One of the affected organs is the liver. Sickle cell disease and its treatment through blood transfusion can lead to significant liver damage. This disease also can cause the liver to regrow abnormally after damage. This can cause high blood pressure in the liver.
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Generally, women with sickle cell trait do not have problems from the disorder. But they may have a lot of urinary tract infections during pregnancy. Pregnant women with sickle cell trait can also have a kind of anemia caused by not having enough iron in their blood.
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SCD occurs when a person inherits two sickle cell genes, one from each parent. SCD makes the red blood cells hard, sticky, and shaped like a sickle. The sickle cells die quickly, so people with SCD always have a shortage of red blood cells. They can also clog up smaller blood vessels and cause other serious problems.
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"The abdomen is a well-known site of sickle cell pain. Abdominal pain due to constipation may be misinterpreted as a worsening vaso-occlusive crisis with subsequent higher doses of narcotics and therefore worsening constipation."
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It is caused by homozygous inheritance of genes for hemoglobin (Hb) S. Sickle-shaped red blood cells cause vaso-occlusion and are prone to hemolysis, leading to severe pain crises, organ ischemia, and other systemic complications.
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How can sickle cell disease affect your immune system? Sickle cells can damage your spleen, the organ that helps fight germs as part of your immune system. That can make you more likely to get pneumonia and other infections.
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Sickle cell anaemia is an inherited autosomal recessive disorder. The leading causes of death in sickle cell diseases (SCD) are infection, pain episodes, acute chest syndrome and stroke [1, 2]. Death can be sudden and unexpected in sickle cell anaemia [1].
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Sickle Cell The sickle-shaped blood cells clog in the capillaries, cutting off circulation. Having two copies of the mutated genes cause sickle cell anemia, but having just one copy does not, and can actually protect against malaria - an example of how mutations are sometimes beneficial.
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The signs and symptoms of sickle cell disease are caused by the sickling of red blood cells. When red blood cells sickle, they break down prematurely, which can lead to anemia. Anemia can cause shortness of breath, fatigue, and delayed growth and development in children.
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['Anxiety.', 'Irritability.', 'Headache.', 'Sweating.', 'Nausea.', 'Fast heart rate.', 'Prolonged or painful erection (priapism)', 'Worsening of panic attacks.']