what is vz in pharmacokinetics?
239033
Vz is the apparent volume of distribution during the terminal phase, i.e. the total amount in the body divided by the plasma concentration (=central. compartment concentration) during the terminal phase.
141746
When taking conventional tablets or oral suspension the peak serum level occurs at approximately 2 hours. If you did not start vomiting until after this period, then the azithromycin will be absorbed regardless of your vomiting episodes.
1379407
Penicillin V is the phenoxymethyl analog of penicillin G. Penicillin V potassium is the potassium salt of penicillin V. Penicillin -VK (Penicillin V Potassium Tablets USP), for oral administration, contain 250 mg (400,000 units) or 500 mg (800,000 units) penicillin V.
719650
CVVHD is the infusion of dialysis fluid into the filter canister The dialysis fluid (dialysate) surrounds the blood filled filter segments. Solutes that are small enough to fit through the membrane of the dialysis filter will move from an area of high concentration to low concentration (diffusion).
3483
Penicillin has low protein binding in plasma, the bioavailability of penicillin depends on the type; penicillin G has a low bioavailability, below 30%, whereas penicillin V has a higher bioavailability between 60 and 70%. Penicillin has a short half life and is excreted via the kidneys.
730125
There are no data available concerning the pharmacokinetic disposition of trazodone or its metabolites in patients with renal and/or liver disease. Therapy with trazodone should be administered cautiously in patients with significantly impaired renal or hepatic function. Dosage adjustments may be necessary.
468700
Cmax – the maximum concentration recorded. tmax – the time take to reach Cmax. AUC (Area Under the Curve) – a measure of the exposure to the drug. t1/2 (elimination half-life) – the time taken for the plasma concentration to fall by half its original value (shown in.
475734
The maintenance dose of ZUBSOLV is generally in the range of 2.9 mg/0.71 mg to 17.2 mg/4.2 mg per day depending on the individual patient and clinical response. Dosages higher than 17.2 mg/4.2 mg per day have not been demonstrated to provide any clinical advantage.
1177579
Pharmacokinetics (PK) Study: Drug Concentration vs. Time in the Body. A pharmacokinetic study provides the basis for determining drug exposures in the body over time. PK parameters are used in the evaluation of the absorption, distribution, metabolism, and excretion (ADME) processes of drugs.
893225
Ve = Elution volume (volume of solvent between injection and elution). Dictated by proportion of porous matrix available to molecules (Kd). Column Parameters. Vs= volume of solvent held in the pores. This is normally approximated to.
1276895
Intravenous or IV push is the rapid administration of a small volume of medication into the patient's vein via a previously inserted intravenous catheter. This method is used when a rapid response to a medication is required, or when the medication cannot be administered via the oral route.
350250
After a drug is administered, it is absorbed into the bloodstream. The circulatory system then distributes the drug throughout the body. Then it is metabolized by the body.
129110
Azivent-XL 200mg Rediuse Oral Suspension is an antibiotic used to treat various types of bacterial infections of the respiratory tract, ear, nose, throat, lungs, skin, and eye in adults and children. It is also effective in typhoid fever and some sexually transmitted diseases like gonorrhea.
1214654
Azithromycin comes as a tablet, an extended-release (long-acting) suspension (liquid), and a suspension (liquid) to take by mouth. The tablets and suspension (Zithromax) are usually taken with or without food once a day for 1–5 days.
134805
min sec min Vmax depends on the structure the enzyme itself and the concentration of enzyme present. KM is a the concentration substrate required to approach the maximum reaction velocity - if [S]>>Km then Vo will be close to Vmax. KM is a concentration. It will have units of: (M),or ( M),etc.
673706
The MTT assay involves the conversion of the water-soluble yellow dye MTT [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide] to an insoluble purple formazan by the action of mitochondrial reductase. Formazan is then solubilized and the concentration determined by optical density at 570 nm.
404755
Clearance is defined as 'the volume of blood cleared of drug per unit time'. ... Drug elimination rate is defined as 'the amount of drug cleared from the blood per unit time' In first order kinetics, elimination rate is proportional to dose, while clearance rate remains independent of the dose.