what is dissolution sink condition definition?
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Sink condition is the ability of the dissolution media to dissolve at least 3 times the amount of drug that is in your dosage form. Having sink conditions helps your dissolution have more robustness as well as being more biologically relevant.
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Types (Processes) of Chemical Weathering 1- Dissolution: Dissolution is the process whereby a mineral dissolves in a solvent as a result of the freeing up of its ions (i.e. transformation of the compound into free ions).
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Dissolution is the process whereby a mineral dissolves in a solvent as a result of the freeing up of its ions (i.e. transformation of the compound into free ions). The most important solvent in nature is water, and the minerals which dissolve most readily or easily are the halides, nitrates, carbonates and sulfates.
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Sinking and Sourcing are terms used to define the control of direct current flow in a load. A sinking digital I/O (input/output) provides a grounded connection to the load, whereas a sourcing digital I/O provides a voltage source to the load. ... The circuit needs a voltage source, a ground, and a load.
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An elevated total dissolved solids concentration does not mean that the water is a health hazard, but it does mean the water may have aesthetic problems or cause nuisance problems. These problems may be associated with staining, taste, or precipitation.
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A measure of possible flow of a standard liquid under fixed conditions through a porous medium when there is no reaction between the liquid and the solids.
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A solution that has some solid present is not a solution, but a heterogeneous mixture. ... Saturated solutions have dissolved the maximum amount of solute possible at a given temperature.
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Changes of state reach equilibrium when the rates of the forward and reverse processes occur at the same rates. For example, when a container is partially filled with liquid water, some of the water will evaporate to the gas phase.
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Task 1: Liquids and solutions A mixture in which a substance has fully dissolved in water is called a solution and the substance is said to be soluble. An example of this type of mixture is sugar in water. Here the sugar dissolves fully to give a clear solution.
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['A saturated solution contains the maximum amount of solute that will dissolve at that temperature. ... ', 'An unsaturated solution contains less than the maximum amount of solute that can be dissolved at that temperature.']
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Dilution is the process of decreasing the concentration of a solute in a solution, usually simply by mixing with more solvent like adding more water to a solution. To dilute a solution means to add more solvent without the addition of more solute.
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Hypoxia, or oxygen depletion, is an environmental phenomenon where the concentration of dissolved oxygen in the water column decreases to a level that can no longer support living aquatic organisms. Hypoxia in the northern Gulf of Mexico is defined as a concentration of dissolved oxygen less than 2 mg/L (2 ppm).
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What features are indicators of rock dissolution? Pits and Cavities. Fractures, or very fine cracks, in rocks that show no significant offset across the joint. They help break rocks into smaller pieces and permit water and roots to penetrate the rock, thereby promoting weathering.
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Dissolution testing is a requirement for all solid oral dosage forms and is used throughout the development life-cycle for product release and stability testing. It is a pivotal analytical test used for detecting physical changes in an active pharmaceutical ingredient and formulated product.
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How does land subsidence contribute to water pollution? Using sinkholes as landfills can cause pollutants to seep into groundwater. Weathering is the physical and chemical breakdown of rocks into smaller pieces and is involved in soil development.
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Water solubility is a measure of the amount of chemical substance that can dissolve in water at a specific temperature. The unit of solubility is generally in mg/L (milligrams per liter) or ppm (parts per million).
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The process of dissolving can be endothermic (temperature goes down) or exothermic (temperature goes up). When water dissolves a substance, the water molecules attract and “bond” to the particles (molecules or ions) of the substance causing the particles to separate from each other.