what is the cause of systemic sclerosis?
239183
The cause of systemic sclerosis is unknown. Swelling of the fingers, intermittent coolness and blue discoloration of the fingers, joints freezing in permanent (usually flexed) positions (contractures), and damage to the gastrointestinal system, lungs, heart, or kidneys may develop.
1418400
It is possible that ME/CFS is caused by a change in the person's immune system and the way it responds to infection or stress. ME/CFS shares some features of autoimmune illnesses (diseases in which the immune system attacks healthy tissues in own body, like in rheumatoid arthritis).
972640
GERD and Scleroderma. Scleroderma is an autoimmune disease that can affect almost every aspect of life — including increasing symptoms of GERD. Scleroderma is an autoimmune disease that causes the skin, and sometimes other organs of the body, to become hard and thick.
440264
['Anemia. You might need to take iron supplements or change your diet. ... ', "Hypothyroidism. You'll be prescribed replacement thyroid hormones.", 'Atherosclerosis. ... ', "Raynaud's disease. ... ", 'Diabetes. ... ', 'Anorexia. ... ', 'Low body weight. ... ', 'Poor circulation.']
425671
Raynaud's syndrome, also known as Raynaud's phenomenon or Raynaud's disease, is a condition that makes your fingers or sometimes other parts of your body feel cold or numb. It results from the narrowing of arteries in your hands or feet, which stops the blood from having normal circulation.
570478
Autoimmune diseases such as psoriasis, lupus and rheumatoid arthritis more than double the risk of cardiovascular disease. A new study shows that immune cells that arise during autoimmune disease cause cholesterol to become trapped inside blood vessels.
754621
This is called idiopathic ILD. Idiopathic pulmonary fibrosis (IPF) is the most common disease of this type. There are also dozens of known causes of ILD, including: Autoimmune diseases (in which the immune system attacks the body) such as lupus, rheumatoid arthritis, sarcoidosis, and scleroderma.
794347
['Infection.', 'Rheumatoid arthritis.', 'Rheumatic fever.', 'Vascular disease.', 'Inflammatory bowel disease.', 'Heart disease.', 'Kidney disease.', 'Certain cancers.']
730177
Because autoimmune conditions are common, there is more research, knowledge, and medications available to treat these conditions. In short, in systemic autoinflammatory diseases, the innate part of the immune systems reacts often without cause and without control.
895832
1. Raynaud's syndrome. Raynaud's syndrome, also called Raynaud's phenomenon, is a condition that causes some areas of your body — usually your fingers — to feel inappropriately cold and numb when you're exposed to cold temperatures or high levels of stress.
133307
['A virus.', 'A bacterial infection.', 'Heat exhaustion.', 'Certain inflammatory conditions such as rheumatoid arthritis — inflammation of the lining of your joints (synovium)', 'A malignant tumor.']
624945
Systemic lupus erythematosus (SLE) and Sjögren's syndrome (SS) may coexist, and they are chronic complex disorders, with an autoimmune background, multifactorial etiology, multiple circulating autoantibodies, and variable prognosis.
1338921
Some common underlying causes of pulmonary hypertension include high blood pressure in the lungs' arteries due to some types of congenital heart disease, connective tissue disease, coronary artery disease, high blood pressure, liver disease (cirrhosis), blood clots to the lungs, and chronic lung diseases like emphysema ...
107542
The exact cause of autoimmune disorders is unknown. One theory is that some microorganisms (such as bacteria or viruses) or drugs may trigger changes that confuse the immune system. This may happen more often in people who have genes that make them more prone to autoimmune disorders.
1447865
['Genetics: Certain disorders such as lupus and multiple sclerosis (MS) tend to run in families. ... ', 'Weight: Being overweight or obese raises your risk of developing rheumatoid arthritis or psoriatic arthritis.']
1211857
If you get sick with a cold or a sinus infection, your immune system is focused on fighting the cold, which can trigger shingles. Other risk factors include stress, sun exposure, medications to prevent organ rejection and cancer treatments. Having had shingles once doesn't mean that you won't get it again.
452455
['chronic obstructive pulmonary disease (COPD)', 'asthma.', 'interstitial lung disease (ILD), including pulmonary fibrosis.', 'bronchiectasis.', 'industrial or occupational lung diseases such as asbestosis, which is caused by being exposed to asbestos.', 'lung cancer.']