COX-2 inhibitor, Bextra, Shows Problems in Heart Patients
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Two small clinical trials showed heart bypass surgery patients taking Bextra, an anti-inflammatory in the same class as the recently withdrawn drug Vioxx, had an increased risk of stroke and heart attack.
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The government is warning of potential heart problems associated with the use of the painkiller Bextra in people who have recently had heart bypass surgery.
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20/12/2004 - The safety of cox-2 inhibitors was plunged into further uncertainty after Pfizer released details of trials that found an increased risk of heart problems with patients taking its painkiller Celebrex.
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US regulators warned yesterday of possible heart risks with Pfizer&#39;s Bextra, delivering another blow to popular pain drugs cox-2 inhibitors such as Vioxx, withdrawn from the market by Merck in September.
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WASHINGTON Dec 9, 2004 - The government is warning of potential heart problems associated with the use of the painkiller Bextra in people who have recently had heart bypass surgery.
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NEW YORK - A new round of trials have shown a boosted risk of heart problems among patients taking the painkiller Celebrex, manufacturer Pfizer Inc.
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The Food and Drug Administration has published a note on its Web site regarding new warnings added to the labeling for Bextra, an arthritis pain drug made by Pfizer (nyse: PFE - news - people ). The warnings
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One of America&#39;s leading heart specialists is calling for less aggressive direct-to-consumer advertising of the arthritis pain drugs known as cox-2 inhibitors, in light of recent reports linking them to increased risk of heart attack and stroke.
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Patients given PfizerÂs painkiller Bextra have more than twice as many heart attacks and strokes as those given placebos, according to preliminary results of a study.
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Description: Americans have recently learned that four popular painkillers -- Vioxx, Celebrex, Bextra and naproxen -- have been linked to an increased risk of heart attack and stroke.
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Celebrex, an arthritis pain reliever used by tens of millions of people, has been found to elevate the risk of heart attack and stroke.
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WASHINGTON (CBS.MW) -- The US Food and Drug Administration said on Thursday that Pfizer&#39;s new pain drug Bextra will carry a labeled warning about a risk of cardiac and blood-clotting problems.
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Doctors writing in a prominent medical journal on Friday recommended that physicians stop prescribing Pfizer Inc.'s Bextra painkiller, just as a large study found the drugmaker's sister drug, Celebrex,  doubled risk of heart attacks.
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More evidence of how painkillers  called COX-2 inhibitors can raise the risk of heart disease was  published Monday, showing Pfizer Inc.'s Bextra can triple the  risk of heart attack and stroke in certain patients.
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NEW YORK -- A new study has linked painkillers Vioxx, Celebrex, and Bextra to increased cardiovascular risk, reinforcing findings of other trials that have already sparked concern over the safety of a popular category of drugs.
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Pfizer warned doctors that one of its best-selling painkillers, Bextra, might increase the risk of heart attack or stroke in coronary artery bypass surgery patients.
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Users of an anti-arthritis drug have been warned that it could cause an increased risk of heart attacks and strokes. A new study linked the drug to the health risks, but users of Celebrex (celecoxib), manufactured