Vioxx heart risks apparent for years
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Scientific evidence of increased heart attack risk associated with popular arthritis drug Vioxx was available as early as 2000, say Swiss scientists, although the drug was only withdrawn in September 2004.
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Washington - The health risks found in pain-relieving drugs known as COX-2 inhibitors, such as Vioxx, underscore the need for health authorities to test drugs already on the market, a top United States (US) cardiologist has warned.
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Patients who discontinue long-term use of anti-inflammatory drugs such as ibuprofen and naproxen run a higher risk of heart attack for a few weeks immediately afterward, a study said on Monday.
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Physicians and researchers estimate that Vioxx, a pain reliever found to increase cardiovascular risks, may have caused as many as 55,000 deaths in the United States.
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Doctors are struggling to decide which pain relievers to prescribe now that they know that drugs like Vioxx and Celebrex pose serious heart risks.
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Research shows that the dangers linking the arthritis drug Vioxx, a COX-2 inhibitor, to an increased risk of heart attacks, were known in 2000, which should have led to its immediate recall.
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A study out Tuesday found that Vioxx users were nearly three times more likely to suffer a heart attack than people taking Celebrex, a similar pain reliever.
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BOSTON (CBS.MW) -- Merck &amp; Co. shares fell more than 10 percent Monday on a news report that the company may have known for years that Vioxx, the pain reliever it recently withdrew from the market, could cause cardiac problems in some patients.
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WASHINGTON (CBS.MW) -- The US Food and Drug Administration could not force Merck to perform safety studies of arthritis drug Vioxx after it hit the market in 1999, but the agency successfully &quot;negotiated&quot; the long-term studies that uncovered Vioxx&#39;s heart
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ASK YOUR DOCTOR ABOUT VIOXX . . . but not for the reasons Merck &amp; Co. recommends. Last week a Food and Drug Administration (FDA) study found a link with heart attacks, and several large health insurers said
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Merck &amp; Co Inc. is evaluating why its withdrawn painkiller Vioxx raises the chance of heart attack and stroke, but it has not found a mechanism of action, a company official said on Monday.
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The arthritis drug Vioxx, used by  millions of people around the world, is being pulled off the  market after a study confirmed long-standing concerns that it  raises the risk of heart attack and stroke, the manufacturer,  Merck & Co. MRK.N, said on Thursday.
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People who take Merck & Co. Inc.'s analgesic Vioxx are nearly three times as likely to have heart attacks as those taking Pfizer Inc.'s Celebrex, according to an independent study published on Monday.
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Scientists in the United States and regulatory agencies in Europe on Wednesdsay questioned whether Celebrex and other pain relievers might raise the same risk of heart problems as those blamed on the arthritis medicine Vioxx.
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FDA researchers say taking high doses of arthritis drug can raise risk of heart attacks. WASHINGTON -- The nation&#39;s largest health management organization is considering changing how it prescribes Vioxx after
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Vioxx was associated with higher odds of heart attack than Celebrex, but the difference may be due to a number of factors, including differences in selectivity for the COX-2 isoenzyme, blood pressure, endothelial function and oxidative stress.
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(Ivanhoe Newswire) -- A new study reveals a greater risk of heart attack associated with Vioxx (rofecoxib) than with Celebrex (celecoxib), although neither drug shows a statistically significant elevated risk of heart attack relative to people who did not