Vioxx heart risks apparent for years
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Scientific evidence of increased heart attack risk associated with popular arthritis drug Vioxx was available as early as 2000, say Swiss scientists, although the drug was only withdrawn in September 2004.
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In the first epidemiological study designed and executed specifically to determine the heart-attack risk associated with COX-2 inhibitors rofecoxib (Vioxx) and celecoxib (Celebrex), researchers at the University of Pennsylvania School of Medicine found a
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(Ivanhoe Newswire) -- A new study reveals a greater risk of heart attack associated with Vioxx (rofecoxib) than with Celebrex (celecoxib), although neither drug shows a statistically significant elevated risk of heart attack relative to people who did not
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U.S. drugs giant Merck & Co Inc. should  have pulled its Vioxx painkiller from the market four years ago  because data showing it raised the risk of heart attacks has  existed since 2000, Swiss scientists said on Friday.
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Professor Garret A FitzGerald, an eminent cardiologists, University of Pennsylvania School of Medicine, says doctors should be cautious about using Vioxx type medicines, especially if the patient is at risk of heart disease.
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Oct. 6, 2004 - Scientists in the United States and regulatory agencies in Europe on Wednesdsay questioned whether Celebrex and other pain relievers might raise the same risk of heart problems as those blamed on the arthritis medicine Vioxx.
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GAITHERSBURG, Md.  - The heart attack and stroke  risks linked to withdrawn arthritis drug Vioxx are an inherent  problem for similar pain pills, Vioxx maker Merck & Co. Inc.  MRK.N told advisers to the U.S. Food and Drug Administration  on Wednesday.
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Scientists in the United States and regulatory agencies in Europe on Wednesdsay questioned whether Celebrex and other pain relievers might raise the same risk of heart problems as those blamed on the arthritis medicine Vioxx.
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The arthritis drug Vioxx, used by  millions of people around the world, is being pulled off the  market after a study confirmed long-standing concerns that it  raises the risk of heart attack and stroke, the manufacturer,  Merck & Co. MRK.N, said on Thursday.
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Most patients who used Celebrex and Vioxx would have done as well on older, cheaper arthritis medications and would have avoided the potential heart and stroke risks of those blockbuster drugs, a new study says.
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Swiss researchers reported yesterday that evidence was clear and overwhelming in 2000 that Vioxx doubled the rate of heart attacks and the drug should have withdrawn.
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Heart risks associated with Merck & Co.'s painkiller Vioxx began much sooner than the company has claimed, The Wall Street Journal Online reported on Tuesday, citing a new study.
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Merck & Co Inc. is evaluating why its withdrawn painkiller Vioxx raises the chance of heart attack and stroke, but it has not found a mechanism of action, a company official said on Monday.
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U.S. drugs giant Merck & Co Inc. should have pulled its Vioxx painkiller from the market four years ago because data showing it raised the risk of heart attacks has existed since 2000, Swiss scientists said on Friday.
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Los Angeles Times - WASHINGTON &#8212; Federal regulators and the drug maker Merck &amp; Co. were aware of risks that the company's Vioxx painkiller could cause serious heart problems before the drug was approved in 1999, government and expert witnesses told a Senate committee Thursday.
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Vioxx, the painkiller recalled last September because of safety concerns, may have caused up to 140,000 cases of serious heart disease in the United States, researchers said on Tuesday.
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NEW YORK -- A new study has linked painkillers Vioxx, Celebrex, and Bextra to increased cardiovascular risk, reinforcing findings of other trials that have already sparked concern over the safety of a popular category of drugs.