Vioxx Linked To Increased Cardiac Death
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A new study shows that the prescription drug Vioxx can drastically increase a person&#39;s risk of sudden cardiac death, and that risk is greater if you take a higher dose, or if you take it for a long time.
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Two studies released yesterday have turned up new evidence that all of the popular arthritis painkillers known as cox-2 inhibitors may put users at greater risk of heart attacks and strokes.
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Sept. 30, 2004 -- Long-term use of the painkiller Vioxx doubles a person&#39;s risk of heart attack and stroke, a huge clinical trial shows.
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Celebrex, an arthritis pain reliever used by tens of millions of people, has been found to elevate the risk of heart attack and stroke.
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Oct. 6, 2004 - Scientists in the United States and regulatory agencies in Europe on Wednesdsay questioned whether Celebrex and other pain relievers might raise the same risk of heart problems as those blamed on the arthritis medicine Vioxx.
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The Wall Street Journal has reported that pharmaceutical company Merck knew as far back as 2000 that its arthritis medication, Vioxx, was linked to an increased risk of heart attack.
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The study&#39;s findings were dramatic: 20 patients on Vioxx had heart attacks. Only four had heart attacks on the comparison drug.
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Merck & Co Inc. is evaluating why  its withdrawn painkiller Vioxx raises the chance of heart  attack and stroke, but it has not found a mechanism of action,  a company official said on Monday.
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NEW YORK  - A new study adds to the  evidence that cardiac risk is increased in Vioxx (rofecoxib)  users, even in those without a history of heart attack. The  results also show that at lower doses of Vioxx, concurrent  aspirin use can reduce the risk and the risk decreases to  normal levels after Vioxx is discontinued.
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Vioxx, the painkiller recalled last  September because of safety concerns, may have caused up to  140,000 cases of serious heart disease in the United States,  researchers said on Tuesday.
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The findings may be relevant to many people who take aspirin to prevent heart problems as well as a COX-2 inhibitor drug like Vioxx for arthritis.
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The arthritis drug rofecoxib (Vioxx) was withdrawn from the market after a study demonstrated that it increases the risk of heart attack and stroke.
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Patients taking Merck & Co.'s Vioxx arthritis drug had 50 percent more heart attacks and cases of sudden cardiac death than those taking Pfizer Inc.'s rival Celebrex drug, according to a large study financed by the U.S. Food and Drug Administration.
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WASHINGTON -- Preliminary results of a new study suggest that high doses of Celebrex, a popular arthritis drug, can dramatically increase a person&#39;s risk of heart attack.
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NEW YORK - A new round of trials have shown a boosted risk of heart problems among patients taking the painkiller Celebrex, manufacturer Pfizer Inc.
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Washington - The health risks found in pain-relieving drugs known as COX-2 inhibitors, such as Vioxx, underscore the need for health authorities to test drugs already on the market, a top United States (US) cardiologist has warned.
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Scientists and European regulators are now questioning the safety of other pain relievers like Vioxx, saying these medications also might raise the risk of heart attack and stroke.