Provides great real life examples to reinforce important points of pharmacology
357134
Provides great real life examples to reinforce important points of pharmacology. I am a retail rph of 20 years and don't get many opportunities to see these real live scenarios. If you don't use it you will lose it. This has been a helpful and enjoyable read.
924401
An excellent quick review.  This book is stream lined, easy to comprehend and fairly good with the number of drugs covered.  It should be coupled with a more comprehensive text.  I would have had a much more difficult time with my Pharmacology class without it.  There is not enough chemistry, but then again it is a review.  Overall - well worth adding to your library.
4562612
This book is well organized and the author hits on the generalities of herbs she lists.  IT is DEFINiTELY something you would want to check with your doctor or  pharmacist for any drug interactions with CURRENT OR NEW Prescriptions.  St. John's Wort had an ill effect on me with my anti-depressants.  But my fault for not checking with the doctor and pharmacist, and I did this prior to reading this book.

Just wanted to share that tidbit of information.

Otherwise, this is well worth the read, and keeping it as a reference and definitely a good  purchase
4960056
Full of examples, this book documents the myriad ways that big pharmaceutical companies have corrupted medical research, prescription practices, regulating agencies, and hospital administrations. Placing profits above public welfare, big pharma has falsified or manipulated drug studies, weakened or undermined regulation, co-opted physicians and editors, and killed patients. Despite the disclaimer in the introduction, there are also multiple references to medicines that work well, that provide more benefit than harm. I only wish I had read this book sooner. A must-read for anyone interested in corruption (defined broadly) in the health sector.
925308
This book just came out but I know a lot about it and about the author before I even got a copy.  In November of last year Mark Chang coauthored a book in this Chapman and Hall series that I reviewed with praise because of the importance of the topic and the way it was demonstrated to work in a variety of real problems in pharmaceutical clinical trials.  This book is even better as it goes more deeply into the methodology, the controversies and the results from simulation studies.  Also it is much more practical because for every case where an application is given a SAS macro is also included to allow the reader to try the methodology for himself.  In March of 2007 I actually designed a two-stage adaptive design with sample size reestimation for bioequivalence trials.  I met mark at a conference where he presented much of his recent work and he was instrumental in helping me through his first book and his journal articles.  This book had already gone to the publisher but he realized that this important design had overlooked.  He added it when the copyedited version came to him.  The design and the simulations related to it are very close to what I actually used.  For those who like to program in R, he provides R code corresponding to each of the SAS macros that he gave.  These programs make the new methodology readily available to interested users. The book is very comprehensive in that it covers a wide variety of applications for phase 2, phase 3 and combined phase trials.  With the FDAs new initiative to speed up the drug discovery process this book will be an invaluable tool to statisticians in the pharmaceutical industry who would like to learn and apply these methods that along with the group sequential methodsare gaining favor within the FDA.
1024985
I have read a lot of drug books in the course of my nursing (RN) education and this book helped me understand Pharmacology. The author, Lehne, is very concise in his presentation of pathophysiology and pharmacology i.e., mechanism of action, pharmacokinetics, adverse effects, interactions, etc. One thing that sets this book apart from the other drug books is the extensive but concise explanation of nursing implications related to each drug. At the end of each chapter, the author lists a summary of Major Nursing Implications which is very helpful and indispensable to students and practicing nurses.
2824671
This is a fast paced book packed with analysis and observation for both professional and personal application. The author has filled the book with great examples of real life situations that leave the reader with practical tools and insights which are very beneficial and not readily available to the public.  A quick read that is informative and educational!
1516259
I'm an Economics student and I'm studying games theory applied to business. This book provides a lot of interesting examples, which can be very useful to understand how games theory can be successfully used to improve (or analyze) decision making in real-world situations.
4621804
It's useful for a Diff Eq course I am taking in which we model specific real life phenomenons, such as drug assimilation.
4038869
After perusing the medical literature on Vitamin K, I ran across a number of compelling scientific papers that support the combined use of Vitamin C and Vitamin K3 for killing cancer tumors.  That led me to April Kirkendoll's book, and I just expected it to be a layman's version of the papers that I had already read.  Not so!  Although the author does explain the use of this therapy, she also brings together a variety of ideas about what cancer cells really are- an underlying mechanism of how all cancer types come to be, what signals influence their behavior in the body, and how we might best direct our research efforts to combat them.

It's a riveting read for anyone who is curious about the big picture of cancer biology.
3785405
This is a really solid book, and every chapter is extremely well-written and researched.
Written by two doctors, the reader discovers that as much as 40% of medications, medical procedures, and treatments may in fact turn out to not only be ineffective, but also harmful.

The fallout and potential negative effects from that include unproven therapies putting patients at risk, lost trust in the medical community, and simply bad advice.  Chapter 8, THE HARMS OF MEDICAL REVERSAL, is outstanding in that regard.

The authors also relate how pharmaceutical and medical device companies can manipulate studies and how treatment guidelines will sometimes endorse treatment(s) that aren't evidence based.

Conditions covered include prostate cancer screenings, mammograms, cholesterol-lowering medications, hormone replacement, and high blood pressure.

Definitely a worthwhile read for anyone wanting to be more diligent and cautious in their medical care.
480674
This book has made a huge difference in the way I have studied for my pharmacology class. After reading Dr. Guerra's other book on memorizing pharmacology, I have found this new book helpful in memorizing a lot of the other information regarding pharmacology. He provides mnemonics and organizes his information in a way that really flows and is easy to follow.
3959238
When I studied my MPH degree at Rutgers School of Public Health, I had taken Dr. Shihs course Clinical Trials: Design and Analysis of Medical Experiments using this book. I strongly recommend this book for graduate-level students who wish to start a career in pharmaceutical industry or for those experienced in clinical trials as a reference book. This book opens the gateway for my further ScD studies at Johns Hopkins Bloomberg School of Public Health. 

There are three major advantages of the book that I would like to highlight. First, it explains profound biostatistic theories into an easy-to-understand approach. This book is worth a read not only for biostatistician, but also for medical students, residents, and public health students and professionals who are interested in developing clinical trials. This book provides essential topics of clinical trial design: Methods of Randomization, Cross-Over Design, Sample Size and Power Calculations, Sequential Design and Methods. These concepts are well discussed, enabling the readers to participate in a clinical trial team and develop of a trial protocol.

Second, the book explains complex statistical analyses adequate for understanding and applications. Using the statistical packages to analyze and report real data, readers would be able to communicate clinical trial results both orally and in writing. Some chapters used recent published medical literature (e.g. JAMA, Clinical Cancer Research) to explain how to design the Methods and Statistical Analysis of a clinical trial and how to criticize statistical methodology.

Third, this book is one of limited clinical trial books coming with homework at the end of each chapter. These well-written homework make the essential theories more easier to digest and implement in real-life experimental studies.

Overall, I highly recommend this book to students, residents, and public health professionals who want to apply basic theory and statistical methods to problems relevant to clinical trials.
934761
While reading this book, I felt like I was a student who signed up for a class called "Your Brain on Food" but instead was somehow switched into one called "Your Brain on Drugs." Not that this was a undesirable switch...just an unexpected one.

And, it's no coincidence that I felt like I was in class while reading this book--the author is, after all, a college professor. The book's presentation, style, and content are rather lecture-like, but, nonetheless effectively accomplish the author's mission of showing how: "anything you consume--the drugs you take, the foods you eat--can affect how your neurons behave, and subsequently, how you think and feel." (p. X)

In the beginning of the book, the author/professor presents a clear overview of basic neurochemistry, nicely summarizing the path of neurotransmitter production, release, reuptake, and inactivation. (I've actually marked this section to revisit again whenever I need a quick neurochemistry refresher.) The rest of the book focuses on how:
"Drugs and the contents of our diet can interact with any of these various processes and impair, or even sometimes enhance, the production of neurotransmitters, as well as impair their storage into synaptic vesicles, alter their release from neurons, modify their interaction with receptor proteins, slow their reuptake, and possibly even stop their enzymatic inactivation. Because your brain is the organ of the mind, drugs and food that do any of these things can have a profound influence on how you think, act, and feel." (pp. 14-15)

Sitting through this lecture, uh, I mean, reading this book, you'll learn the key responses associated with specific neurotransmitters, including: learning, memory, and attention with acetylcholine; arousal and euphoria with norepinephrine and dopamine; processing of sensory information and mood with serotonin; excitation and neuroplasticity with glutamate;  inhibition with GABA; and euphoria and pain reduction with opiates.

And, receiving the full benefits of being taught by a professor, you'll be entertained with stories of his students who have vividly demonstrated the effects of drugs on various neurotransmitter systems.  Let's see...there was the one student who became temporarily paralyzed after drinking alcohol at fraternity parties to the delight of others who would place his limbs in odd positions. And, then there was the student who would collect her boyfriend's urine after he used the stimulant mescaline, realizing she was able to experience the high, without the nasty GI side effects experienced when taken in its "pre-digested" from. And, then there was that other student who consumed an entire container of nutmeg dissolved in applesauce, but instead of being able to enjoy the sought-after aphrodisiac effects, he was stuck in the bathroom for the weekend. These stories might stick in your mind long after the more academic details of the drug-induced neurotransmitter responses have faded.

(True to lecture form, at the end of his teachings, the professor even provides you with a little quiz to see if you really were paying attention.)

Although the content and delivery of the book might not be what's expected, what it does provide is certainly worthwhile.
4149663
I purchased this book to help me with my pharmacology class. I was able to learn how to calculate medication doses and this book really made it easy and gave lots of exercise problems to help instill the formulas. I did not rate this book a 5 because the first few chapters were of basic math skills which seemed really basic but for someone who is struggling this would be a great book to start a foundation on if you are going into the medical field
3829224
I am a pharmacologist who is just a few years older than the author.  I couldn't put the book down.  I identified with so many of her experiences and outcomes.  She helped me put so many of my own life experiences in perspective.  Now my daughter is beginning her career in science, and I left the book with her.  I hope it will help her feel that she is not alone, when she is the only woman in the room.  Yes, maybe attitudes have changed in academia, but maybe they are just more subtle.
4347981
I work for a Pharmaceutical Company so have been aware for a long time of the relationships Big Pharma foster with business to sell their products. However even I was stunned by the financial relationships that many leading Medical personnel have with Pharmaceutical companies. The author does a great job of laying bare these relationships and pointing out the consequences for patients relying on the so called impartiality of doctors so they make choices of drugs based on their efficacy and safety rather than prescribing drugs based on free so called Educational seminars in salubrious surroundings where the doctor is wined and dined at the expense of Big Pharma. The FDA is shown for the corrupt organisation it is ,dependent on funding from the Pharmaceutical Industy.<a data-hook="product-link-linked" class="a-link-normal" href="/On-the-Take-How-Medicine-s-Complicity-with-Big-Business-Can-Endanger-Your-Health/dp/B002QGSXPA/ref=cm_cr_arp_d_rvw_txt?ie=UTF8">On the Take: How Medicine's Complicity with Big Business Can Endanger Your Health</a>