what diseases are like als?
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['Myasthenia gravis.', 'Lambert-Eaton myasthenic syndrome.', 'Lyme disease.', 'Poliomyelitis and post-poliomyelitis.', 'Heavy metal intoxication.', 'Kennedy syndrome.', 'Adult-onset Tay-Sachs disease.', 'Hereditary spastic paraplegia.']
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An estimated 5 to 10 percent of ALS is familial and caused by mutations in one of several genes. The pattern of inheritance varies depending on the gene involved. Most cases are inherited in an autosomal dominant pattern, which means one copy of the altered gene in each cell is sufficient to cause the disorder.
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It is unclear why some people with a mutated gene develop the disease and other people with a mutated gene do not. Less frequently, ALS is inherited in an autosomal recessive pattern, which means both copies of the gene in each cell have mutations.
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ALS affects nerve cells in the brain and spinal cord, leading to muscle weakness, a loss of motor function, paralysis, breathing problems, and, eventually, death. Most people with ALS will live between 3 and 5 years after symptoms appear.
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ALS, MS, and MD: How do they differ? Often, the public confuses Multiple Sclerosis, Muscular Dystrophy, and Amyotrophic Lateral Sclerosis. ALS is a rapidly progressive and fatal neuromuscular disease. MS is a scarring and hardening of the sheath around the nerves in the brain, spinal cord, and optic nerve.
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Inheritance Pattern About 90 to 95 percent of ALS cases are sporadic, which means they are not inherited. An estimated 5 to 10 percent of ALS is familial and caused by mutations in one of several genes. The pattern of inheritance varies depending on the gene involved.
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He called it Amyotrophic Lateral Sclerosis (ALS). There are virtually no other neurological conditions in which both these processes occur simultaneously. Nearly 90 percent of patients with MND have the mixed ALS form of the disease, so that the terms MND and ALS are commonly used to mean the same thing.
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Summary: Medical researchers demonstrate that ALS -- known as Lou Gehrig's disease -- damages neurons in parts of the brain responsible for cognition and behavior. The scientists provide evidence that ALS affects more than just the motor cortex, the part of the brain responsible for motor function.
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Parkinson's disease (PD) is a movement disorder that afflicts over one million in the U.S.; amyotrophic lateral sclerosis (ALS or Lou Gehrig's disease) is less prevalent but also has a high incidence. The two disorders sometimes present together, making a comparative study of interest.
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The Difference between Motor Neuron Disease (MND) & ALS. The terms Motor Neuron Disease and ALS are often used interchangeably. In reality, however, MND is the generic term for many different types of neurological disorders with ALS being one of them.
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ALS affects the nerve cells that control voluntary muscle movements such as walking and talking (motor neurons). ALS causes the motor neurons to gradually deteriorate, and then die. Motor neurons extend from the brain to the spinal cord to muscles throughout the body.
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People living with ALS often experience muscle twitching or fasciculations, as the signal from the nerves to the muscles become more disrupted. These are caused by the tips of nerves (axons) coming into contact with nearby muscles, sending an electrical signal which causes the muscle to twitch.
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Etiology. MS is an autoimmune disease that causes the body to attack the myelin sheath that insulates nerve cell fibers in the brain and the spinal cord. In contrast, ALS is a motor neuron disease that mainly affects the actual motor neuron cells in the brain and spinal cord.
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Amyotrophic Lateral Sclerosis (ALS), commonly known as Lou Gehrig's disease, is a progressive neuromuscular disease. ALS is characterized by a progressive degeneration of motor nerve cells in the brain (upper motor neurons) and spinal cord (lower motor neurons).
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Amyotrophic Lateral Sclerosis (ALS) and other neurodegenerative conditions, including Parkinson's disease (PD), share some common traits. ALS and Parkinson's are both progressive conditions, which means they get worse over time.
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Both conditions cause scarring or hardening around nerve cells called sclerosis, but the difference lies in the way sclerosis occurs. In early stages, several symptoms of ALS and MS can be similar, like muscle stiffness, muscle spasms, difficulty walking, and fatigue.
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(Amyotrophic lateral sclerosis) Although some CIDP symptoms may appear similar to those of ALS, ALS does not cause numbness, tingling, or uncomfortable sensations. Also, ALS commonly causes symptoms such as muscle twitching, weight loss, and muscle wasting as well as problems speaking, breathing, and swallowing.