does wellbutrin make you eat more?
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A: Wellbutrin (bupropion) is an antidepressant. Appetite changes, both increased and decreased, have been reported by patients taking Wellbutrin. The exact relationship between antidepressants and weight gain isn't clear, but weight gain is a reported side effect of nearly all antidepressants.
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More important, these can be risky drugs, especially when taken without a doctor's supervision. Although drug companies and independent researchers have studied the weight-loss effects of many of these drugs, including Wellbutrin and Topamax, to date the FDA hasn't approved any of them for weight loss.
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One antidepressant, Wellbutrin (bupropion), has been associated with insomnia. However, studies that have examined electrical activity of the brain in patients taking bupropion indicate the drug actually increases REM sleep time.
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Two cases of tactile hallucinations ("bugs crawling over skin") have been reported in association with bupropion extended-release (200 mg twice daily) therapy. In both cases the symptoms abated following a reduction in the total daily dose of bupropion (300 mg daily). Insomnia may also be dose-dependent.
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Bupropion works by inhibiting the reuptake of dopamine, serotonin, and norepinephrine; an action that results in more dopamine, serotonin, and norepinephrine to transmit messages to other nerves.
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Some people have anxiety-related symptoms, such as restlessness or agitation, shortly after starting Wellbutrin. Because these symptoms may be related to the dosage of your medication, speak with your doctor if you're feeling anxious after starting Wellbutrin.
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Half-Life of Wellbutrin (Bupropion) The half-life of any medication is the amount of time it stays in your system when it hits half of its effectiveness. At between 33 to 37 hours, the half-life of Wellbutrin is exceptionally long for an antidepressant.
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Side effects with bupropion are generally mild and often resolve over the first 1-2 weeks of treatment as you continue to take the medication. The most commonly reported side effects of bupropion are headache, weight loss, dry mouth, trouble sleeping, nausea, dizziness, constipation, fast heartbeat, and sore throat.
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WELLBUTRIN SR 400 mg per day: Abdominal pain, agitation, anxiety, dizziness, dry mouth, insomnia, myalgia, nausea, palpitation, pharyngitis, sweating, tinnitus, and urinary frequency.
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Those taking Wellbutrin lost an average of 13 lbs (5.8 kg) in 12 weeks compared to 6 lbs (2.8 kg) in the placebo group. 57% of patients taking Wellbutrin lost 5% or more of their weight compared to only 28% in the placebo group.
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Common withdrawal symptoms of Wellbutrin include irritability, dizziness, headaches, aggression, flu symptoms, anxiety, depression, sleep changes, nausea, cramps, tremors, suicidal thoughts, excessive sweating, trouble balancing and difficulty tolerating warm temperatures.
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Some antidepressants may be less likely to affect weight. Effexor and Serzone generally do not cause weight gain, while Wellbutrin can cause weight loss.
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Another hypothesis is that weight gained while on an SSRI may be partially due to the fact that some people don't feel like eating when they're depressed and so they lose weight. Once they start feeling better while on medication, their appetite comes back, they eat more, and eventually return to their regular weight.
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Wellbutrin (Bupropion) Helps you relax. Buspar (buspirone) relieves anxiety with less drowsiness and abuse potential than other anti-anxiety medicines, but it takes time to work and effects might wear off over time. Improves mood.
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Studies have shown that bupropion (Wellbutrin) is just as effective as SSRIs for the remission of major depressive symptoms. Those taking bupropion are less likely to suffer symptoms of sleepiness and fatigue than those treated with SSRIs.
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Bottom Line. Naltrexone/bupropion produces clinically significant weight loss when combined with a diet and exercise program. It decreases body weight in patients with diabetes, but its effect on diabetic outcomes is not known. A significant proportion of patients will experience adverse effects.
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Wellbutrin is a norepinephrine and dopamine reuptake inhibitor (NDRI), and it works by keeping the neurotransmitters norepinephrine and dopamine available to the brain's neurons for longer. This helps improve concentration, focus, and other ADHD symptoms.