how does type 1 diabetes affect metabolism?
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Profound metabolic changes occur in people with type 1 diabetes mellitus during insulin deprivation. These include an increase in basal energy expenditure and reduced mitochondrial function. In addition, protein metabolism is significantly affected during insulin deprivation.
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Previous studies have shown that the liver's capacity to store glycogen is reduced in patients with type 1 diabetes mellitus, but it remains unclear whether this is due to hyperglycemia (a high blood glucose level), or whether the route of insulin supply could contribute to this occurrence.
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Meal timing is very important for people with type 1 diabetes. Meals must match insulin doses. Eating meals with a low glycemic load (index) makes meal timing easier. Low glycemic load meals raise blood sugar slowly and steadily, leaving plenty of time for the body (or the injected insulin dose) to respond.
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And because the cells end up starving for energy, people with type 1 diabetes are often hungry and have trouble keeping up their weight. They may also be weak, irritable, tired, and troubled by an upset stomach.
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Type 1 diabetes is a condition that causes the level of glucose (a type of sugar) in your blood to become too high. It happens when your body is not able to produce enough of a hormone called insulin, which controls blood glucose.
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Signs and symptoms The classical symptoms of type 1 diabetes include: polyuria (increased urination), polydipsia (increased thirst), dry mouth, polyphagia (increased hunger), fatigue, and weight loss. Type 1 diabetes is often diagnosed when diabetic ketoacidosis occurs.
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Insulin is needed to move blood sugar (glucose) into cells. Inside the cells, glucose is stored and later used for energy. With type 1 diabetes, beta cells produce little or no insulin.
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Glucose levels are controlled by a hormone called insulin, which is made in the pancreas. In type 1 diabetes, the pancreas does not make enough insulin. Undiagnosed or untreated type 1 diabetes can cause weight loss. Glucose builds up in the bloodstream if insulin isn't available to move it into the body's cells.
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With type 1 diabetes, beta cells produce little or no insulin. Without enough insulin, glucose builds up in the bloodstream instead of going into the cells. This buildup of glucose in the blood is called hyperglycemia.
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Type 1 diabetes (T1D), previously known as juvenile diabetes, is a form of diabetes in which very little or no insulin is produced by the pancreas. Insulin is a hormone required for the body to use blood sugar. Before treatment this results in high blood sugar levels in the body.
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Type 1 diabetes (T1D) is an autoimmune disease that occurs when a person's pancreas stops producing insulin, the hormone that controls blood-sugar levels. T1D develops when the insulin-producing pancreatic beta cells are mistakenly destroyed by the body's immune system.
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Signs of type 1 diabetes include: Weight loss—despite eating more. Rapid heart rate. Reduced blood pressure (falling below 90/60)
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In some women who have type 1 diabetes, the hormonal changes that come with menstruation can cause changes in blood glucose levels. Monitoring levels and adjusting insulin accordingly is key to managing this monthly shift. The same hormones that control your menstrual cycle can also affect your blood glucose levels.
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If you have type 1 diabetes, your pancreas makes little to no insulin. You need to inject insulin regularly to metabolize glucose. For Type 1 diabetes, there's no cure, and it can't be reversed. But it can be managed.
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People with type 1 diabetes are at a heightened risk for mental health issues, including diabetes distress, depression, anxiety, and disordered eating. However, these are all treatable disorders. It is important to pay attention to your feelings about having diabetes or taking care of someone who has diabetes.
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Long-term high blood sugar levels in people with type 1 diabetes appears to result in chronic inflammation, researchers say, which can impair organs, nerves and blood vessels.
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In fact a dramatic loss of weight is one of the key symptoms of type 1 diabetes. Rather the problem of weight gain and obesity can develop in some people with type 1 diabetes following their diagnosis. Traditionally, people with type 1 diabetes have tended to be underweight.