what does it mean when you have low urea?
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A low BUN value may be caused by a diet very low in protein, malnutrition, or severe liver damage. Drinking excessive amounts of liquid may cause overhydration and cause a low BUN value.
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['Pregnancy.', 'Low-protein diet.', 'Overhydration.', 'Advanced liver disease (cirrhosis, liver failure)', 'Inherited defect in “urea cycle” enzymes (reduced urea synthesis)']
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Azotemia and uremia are two different types of kidney conditions. Azotemia is when there's nitrogen in your blood. Uremia occurs when there's urea in your blood. However, they're both related to kidney disease or injury.
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Urea is produced from the conversion of ammonia. Ammonia comes from the breakdown of amino acids which can be dangerous if too much ammonia is in the body. Uric acid is produced from purines in foods after it has been digested.
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Amino acids are made available, & deficiency does not occur immediately. Constantly replenished by dietary proeins. Urea excretion is the index of Nitrogen loss from body. It should be replenished by dietary protein to maintain Nitrogen balance.
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Not consuming enough protein can also cause muscle cramping, weakness, and soreness. Your body will take protein from muscle tissue and use it as energy to support other vital body functions when protein is low. This eventually causes muscle wasting or atrophy as a direct result of chronic, low dietary protein.
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Dehydration is the most common cause of decreased urine output. Typically, dehydration occurs when you're ill with diarrhea, vomiting, or another illness, and can't replace the fluids that you're losing. When this happens, your kidneys retain as much fluid as possible.
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Generally, a high serum creatinine level means that your kidneys aren't working well. Your creatinine level may temporarily increase if you're dehydrated, have a low blood volume, eat a large amount of meat or take certain medications.
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High A/G ratio: This can be a sign of disease in your liver, kidney, or intestines. It's also linked to low thyroid activity and leukemia. If your doctor feels any of your levels are too high or low, you may need to have more precise blood or urine tests.
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Insufficient protein in your diet reduces lean body mass, muscle strength, and function. Not consuming enough protein can also cause muscle cramping, weakness, and soreness. Your body will take protein from muscle tissue and use it as energy to support other vital body functions when protein is low.
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Low urine urobilinogen may result from complete obstructive jaundice or treatment with broad-spectrum antibiotics, which destroy the intestinal bacterial flora. (Obstruction of bilirubin passage into the gut or failure of urobilinogen production in the gut.)
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Patients with reduced eGFR also had higher CRP levels which was associated with lower serum albumin levels. But the reason for the hypoalbuminemia in CKD patients does not appear to be due to GI symptoms/decreased protein intake or inflammation. A diminished appetite and nausea/vomiting are classic “uremic symptoms”.
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Dehydration occurs when you don't drink enough fluids. If you're dehydrated, you may notice that your urine is a dark yellow or orange color and smells like ammonia.
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Amino acids regulate haemodynamics and proteolysis and maintain integrity of the kidney. Abnormal plasma and muscle amino acid profiles in chronic renal failure (i.e. low essentials and tyrosine with high nonessentials) first indicated malnutrition, which can be partially corrected by supplementation.
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Dehydration -- When your body is dehydrated, the amount of uric acid in your body rises, and your kidneys' ability to get rid of extra uric acid decreases. So when your body doesn't have enough water, you can be more likely to get a gout attack.
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Uremia is life-threatening because too much nitrogen in the blood is toxic to the body. Symptoms of uremia include confusion, loss of consciousness, low urine production, dry mouth, fatigue, weakness, pale skin or pallor, bleeding problems, rapid heart rate (tachycardia), edema (swelling), and excessive thirst.
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Low albumin levels can also indicate chronic malnutrition from protein losing enteropathy. This is often caused or exacerbated by ulcerative colitis, but can also be seen in cardiac disease and systemic lupus erythematosus.