can klinefelter syndrome affect females?
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Klinefelter syndrome (47,XXY) results from an additional X chromosome on an XY background; therefore, this condition affects only males.
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KBG syndrome is a rare disorder that has been reported in more than 150 individuals in the medical literature, though there are likely more who have not been recorded in the literature. For unknown reasons, males are affected more often than females.
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Turner syndrome, a condition that affects only females, results when one of the X chromosomes (sex chromosomes) is missing or partially missing. Turner syndrome can cause a variety of medical and developmental problems, including short height, failure of the ovaries to develop and heart defects.
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Side effects have also been reported with the HCG diet and include fatigue, irritability, restlessness, depression, fluid buildup (edema), and swelling of the breasts in boys and men (gynecomastia). Another serious concern is the risk of blood clots forming and blocking blood vessels (thromboembolism).
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Low estrogen levels can interfere with sexual development and sexual functions. They can also increase your risk of obesity, osteoporosis, and cardiovascular disease.
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Both women and men with Down's syndrome can be fertile, although both sexes have a reduced fertility rate. They therefore need advice on, and access to, contraception. People with Down's syndrome need careful and sensitive advice about having children, as there are a number of issues to consider.
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Though FXS occurs in both genders, males are more frequently affected than females, and generally with greater severity. Life expectancy is not affected in people with FXS because there are usually no life-threatening health concerns associated with the condition.
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"Autosomal" means that the gene is on one of the first 22 pairs of chromosomes that do not determine gender, so that males and females are equally affected by the disease.
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Determine if the chart shows an autosomal or sex-linked (usually X-linked) trait. For example, in X-linked recessive traits, males are much more commonly affected than females. In autosomal traits, both males and females are equally likely to be affected (usually in equal proportions).
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Thinning hair due to the effects of male hormones (androgens) is called androgenic alopecia. It is a major source of psychological distress to women. This male-pattern hair loss is often seen in women with polycystic ovary syndrome (PCOS), congenital adrenal hyperplasia, and other disorders of male hormone excess.
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Developmental delays and behavioral problems are also possible, but these characteristics vary widely among affected boys and men, are not unique to 47,XYY and are managed no differently from in 46,XY males. Aggression is not seen more frequently in 47,XYY males.
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Klinefelter syndrome is a genetic condition in which a boy is born with an extra X chromosome. Instead of the typical XY chromosomes in men, they have XXY, so this condition is sometimes called XXY syndrome.
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Thus, males can have a disease like hemophilia if they inherit an affected X chromosome that has a mutation in either the factor VIII or factor IX gene. Females can also have hemophilia, but this is much rarer. In such cases both X chromosomes are affected or one is affected and the other is missing or inactive.
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In most cases, males experience more severe symptoms of the disorder than females. A characteristic of X-linked inheritance is that fathers cannot pass X-linked traits to their sons (no male-to-male transmission). X-linked recessive disorders are also caused by mutations in genes on the X chromosome.
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['Infertility. Estrogen is one of the hormones your body uses to produce sperm. ... ', 'Gynecomastia. Increased estrogen can cause more breast tissue to develop than normal. ... ', 'Erectile dysfunction (ED). ... ', 'Slowed growth. ... ', 'Epiphyseal closure.']
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There's no cure for Klinefelter syndrome, but some of the problems associated with the condition can be treated if necessary. Possible treatments include: testosterone replacement therapy. speech and language therapy during childhood to help with speech development.
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The balance between free testosterone and estrogen is also affected by serum levels of sex hormone—binding globulin, which is the proposed mechanism of gynecomastia in certain conditions, such as hyperthyroidism, chronic liver disease, and the use of some medications such as spironolactone.