is myxedema coma an autoimmune disease?
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What causes myxedema? Hypothyroidism occurs when the thyroid stops functioning properly. This may be caused by: an autoimmune condition, including Hashimoto's disease.
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In autoimmunity. An organ-specific disease is one in which an immune response is directed toward antigens in a single organ. Examples are Addison disease, in which autoantibodies attack the adrenal cortex, and myasthenia gravis, in which they attack neuromuscular cells.
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Autoimmune diseases do not cause sepsis, but people with certain types of autoimmune diseases are at higher risk of developing infections, which can trigger sepsis. As well, medications that may be used to treat some autoimmune disorders can weaken your immune system, making it easier for you to develop an infection.
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This means your thyroid symptoms are probably not caused by an autoimmune disease. Positive: antibodies to TPO and/or Tg were found. This may mean you have Hashimoto disease. Most people with Hashimoto disease have high levels of one or both of these types of antibodies.
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Thyroid peroxidase antibody (TPO)—the most common test for autoimmune thyroid disease; it can be detected in Graves disease or Hashimoto thyroiditis. Thyroglobulin antibody (TGAb)— this antibody targets thyroglobulin, the storage form of thyroid hormones.
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Autoimmune polyendocrine syndrome type II, also known as Schmidt syndrome, is a rare autoimmune disorder in which there is a steep drop in production of several essential hormones by the glands that secrete these hormones.
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A serious problem called thyroid storm can happen if Graves' disease is not treated and you have too much thyroid hormone. The buildup of thyroid hormone causes severe restlessness, fever, confusion, sweating, and diarrhea. Your heart may beat very fast and your blood pressure can get very high.
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Autoimmune Addison disease affects the function of the adrenal glands, which are small hormone-producing glands located on top of each kidney. It is classified as an autoimmune disorder because it results from a malfunctioning immune system that attacks the adrenal glands.
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If you have high levels of antithyroglobulin antibodies in your blood, it may be a sign of serious autoimmune disorder, such as Graves' disease or Hashimoto thyroiditis. In some cases, you may have antithyroglobulin antibodies in your blood without any specific complications.
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Potential Dangers of Having Hypothyroidism Left untreated, the symptoms of hypothyroidism will usually progress. Rarely, complications can result in severe life-threatening depression, heart failure, or coma. Hypothyroidism can often be diagnosed with a simple blood test: the thyroid hormone panel.
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Advertisement. The presence of TPO antibodies in your blood suggests that the cause of thyroid disease is an autoimmune disorder, such as Hashimoto's disease or Graves' disease. In autoimmune disorders, your immune system makes antibodies that mistakenly attack normal tissue.
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Myxedema is another term for severely advanced hypothyroidism. This is a condition that occurs when your body doesn't produce enough thyroid hormone. The thyroid is a small gland that sits right at the front of your neck. It releases hormones that help your body regulate energy and control a wide variety of functions.
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Autoimmune disease happens when the body's natural defense system can't tell the difference between your own cells and foreign cells, causing the body to mistakenly attack normal cells. There are more than 80 types of autoimmune diseases that affect a wide range of body parts.
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There is no cure for Hashimoto's thyroiditis. The timeframe of the autoimmune process and inflammation will continue is not predictable. In the vast majority of patients, hypothyroidism results from the inflammatory process.
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The hyponatremia seen in myxedema coma is a result of decreased free water clearance. Elevated levels of antidiuretic hormone and/or diminished blood flow to the kidneys are believed to be responsible for the inability to excrete free water. 19,20 Hyponatremia is classically associated with a low serum osmolality.
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It is believed to be an autoimmune disease -- one in which the immune system mistakenly attacks healthy tissue. It occurs after a mild infection, surgery or, rarely, after an immunization.
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Lichen planus is an autoimmune disease and may be associated with various other autoimmune diseases. So we propose an autoimmune origin of acquired generalized anhidrosis, similar to autoimmune thyroiditis. In autoimmune thyroiditis, initially there is hyperthyroidism followed by a phase of hypothyroidism.