label
int64
Standardized_SMILES
string
MaxAbsEStateIndex
float64
MaxEStateIndex
float64
MinAbsEStateIndex
float64
MinEStateIndex
float64
qed
float64
SPS
float64
MolWt
float64
HeavyAtomMolWt
float64
ExactMolWt
float64
NumValenceElectrons
int64
NumRadicalElectrons
int64
MaxPartialCharge
float64
MinPartialCharge
float64
MaxAbsPartialCharge
float64
MinAbsPartialCharge
float64
FpDensityMorgan1
float64
FpDensityMorgan2
float64
FpDensityMorgan3
float64
BCUT2D_MWHI
float64
BCUT2D_MWLOW
float64
BCUT2D_CHGHI
float64
BCUT2D_CHGLO
float64
BCUT2D_LOGPHI
float64
BCUT2D_LOGPLOW
float64
BCUT2D_MRHI
float64
BCUT2D_MRLOW
float64
AvgIpc
float64
BalabanJ
float64
BertzCT
float64
Chi0
float64
Chi0n
float64
Chi0v
float64
Chi1
float64
Chi1n
float64
Chi1v
float64
Chi2n
float64
Chi2v
float64
Chi3n
float64
Chi3v
float64
Chi4n
float64
Chi4v
float64
HallKierAlpha
float64
Ipc
float64
Kappa1
float64
Kappa2
float64
Kappa3
float64
LabuteASA
float64
PEOE_VSA1
float64
PEOE_VSA10
float64
PEOE_VSA11
float64
PEOE_VSA12
float64
PEOE_VSA13
float64
PEOE_VSA14
float64
PEOE_VSA2
float64
PEOE_VSA3
float64
PEOE_VSA4
float64
PEOE_VSA5
float64
PEOE_VSA6
float64
PEOE_VSA7
float64
PEOE_VSA8
float64
PEOE_VSA9
float64
SMR_VSA1
float64
SMR_VSA10
float64
SMR_VSA2
float64
SMR_VSA3
float64
SMR_VSA4
float64
SMR_VSA5
float64
SMR_VSA6
float64
SMR_VSA7
float64
SMR_VSA8
float64
SMR_VSA9
float64
SlogP_VSA1
float64
SlogP_VSA10
float64
SlogP_VSA11
float64
SlogP_VSA12
float64
SlogP_VSA2
float64
SlogP_VSA3
float64
SlogP_VSA4
float64
SlogP_VSA5
float64
SlogP_VSA6
float64
SlogP_VSA7
float64
SlogP_VSA8
float64
SlogP_VSA9
float64
TPSA
float64
EState_VSA1
float64
EState_VSA10
float64
EState_VSA11
float64
EState_VSA2
float64
EState_VSA3
float64
EState_VSA4
float64
EState_VSA5
float64
EState_VSA6
float64
EState_VSA7
float64
EState_VSA8
float64
EState_VSA9
float64
VSA_EState1
float64
VSA_EState10
float64
VSA_EState2
float64
VSA_EState3
float64
VSA_EState4
float64
VSA_EState5
float64
VSA_EState6
float64
VSA_EState7
float64
VSA_EState8
float64
VSA_EState9
float64
FractionCSP3
float64
HeavyAtomCount
int64
NHOHCount
int64
NOCount
int64
NumAliphaticCarbocycles
int64
NumAliphaticHeterocycles
int64
NumAliphaticRings
int64
NumAmideBonds
int64
NumAromaticCarbocycles
int64
NumAromaticHeterocycles
int64
NumAromaticRings
int64
NumAtomStereoCenters
int64
NumBridgeheadAtoms
int64
NumHAcceptors
int64
NumHDonors
int64
NumHeteroatoms
int64
NumHeterocycles
int64
NumRotatableBonds
int64
NumSaturatedCarbocycles
int64
NumSaturatedHeterocycles
int64
NumSaturatedRings
int64
NumSpiroAtoms
int64
NumUnspecifiedAtomStereoCenters
int64
Phi
float64
RingCount
int64
MolLogP
float64
MolMR
float64
fr_Al_COO
int64
fr_Al_OH
int64
fr_Al_OH_noTert
int64
fr_ArN
int64
fr_Ar_COO
int64
fr_Ar_N
int64
fr_Ar_NH
int64
fr_Ar_OH
int64
fr_COO
int64
fr_COO2
int64
fr_C_O
int64
fr_C_O_noCOO
int64
fr_C_S
int64
fr_HOCCN
int64
fr_Imine
int64
fr_NH0
int64
fr_NH1
int64
fr_NH2
int64
fr_N_O
int64
fr_Ndealkylation1
int64
fr_Ndealkylation2
int64
fr_Nhpyrrole
int64
fr_SH
int64
fr_aldehyde
int64
fr_alkyl_carbamate
int64
fr_alkyl_halide
int64
fr_allylic_oxid
int64
fr_amide
int64
fr_amidine
int64
fr_aniline
int64
fr_aryl_methyl
int64
fr_azide
int64
fr_azo
int64
fr_barbitur
int64
fr_benzene
int64
fr_benzodiazepine
int64
fr_bicyclic
int64
fr_diazo
int64
fr_dihydropyridine
int64
fr_epoxide
int64
fr_ester
int64
fr_ether
int64
fr_furan
int64
fr_guanido
int64
fr_halogen
int64
fr_hdrzine
int64
fr_hdrzone
int64
fr_imidazole
int64
fr_imide
int64
fr_isocyan
int64
fr_isothiocyan
int64
fr_ketone
int64
fr_ketone_Topliss
int64
fr_lactam
int64
fr_lactone
int64
fr_methoxy
int64
fr_morpholine
int64
fr_nitrile
int64
fr_nitro
int64
fr_nitro_arom
int64
fr_nitro_arom_nonortho
int64
fr_nitroso
int64
fr_oxazole
int64
fr_oxime
int64
fr_para_hydroxylation
int64
fr_phenol
int64
fr_phenol_noOrthoHbond
int64
fr_phos_acid
int64
fr_phos_ester
int64
fr_piperdine
int64
fr_piperzine
int64
fr_priamide
int64
fr_prisulfonamd
int64
fr_pyridine
int64
fr_quatN
int64
fr_sulfide
int64
fr_sulfonamd
int64
fr_sulfone
int64
fr_term_acetylene
int64
fr_tetrazole
int64
fr_thiazole
int64
fr_thiocyan
int64
fr_thiophene
int64
fr_unbrch_alkane
int64
fr_urea
int64
1
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N#Cc1ccc(C2CCC(N3CCC4(CCOC4=O)CC3)CC2)cc1
12.018801
12.018801
0.052476
-0.156558
0.773078
29.32
338.451
312.243
338.199428
132
0
0.311799
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0.311799
1.04
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16.540711
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3.025045
1.303313
660.131619
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6.726214
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4.969693
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959,108.718247
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5.969305
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12.132734
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36.607451
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53.33
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4.794537
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11.384296
18.566629
37.915429
31.246738
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12.132734
23.101865
9.998755
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14.635715
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10.985262
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0.619048
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4.516413
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3.61358
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O=c1[nH]c(=O)n(C2CCCO2)cc1F
12.853593
12.853593
0.450139
-0.996068
0.692713
21.357143
200.169
191.097
200.05972
76
0
0.330121
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0.357865
0.330121
1.571429
2.357143
3
19.142225
10.319262
2.189919
-2.110838
2.198158
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4.883017
0.051672
2.636033
2.471699
444.634993
10.129392
7.325944
7.325944
6.681541
4.308536
4.308536
3.111253
3.111253
2.140227
2.140227
1.454703
1.454703
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2,343.433741
9.137814
3.375217
1.480599
78.136733
4.736863
6.227901
0
5.817221
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5.689743
14.345615
4.794537
4.390415
0
0
12.841643
6.606882
6.196844
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0
9.551078
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19.069544
6.606882
32.852149
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0
11.24901
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0
16.15796
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5.817221
19.069544
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0
0
64.09
23.294132
13.979489
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13.027704
17.184765
0
0
4.983979
0
4.736863
19.115683
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23.843002
0
-1.631901
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0
1.925254
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0
0.5
14
1
5
0
1
1
0
0
1
1
1
0
4
1
6
2
1
0
1
1
0
1
2.203007
2
-0.0153
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0
0
C=C(C)Cn1c(Cc2cnn(C)c2)nnc1N1CCN(C[C@@H]2CCOC2)CC1
5.521948
5.521948
0.698799
0.698799
0.670427
20.785714
385.516
354.268
385.259009
152
0
0.227141
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0.227141
1.25
2.071429
2.714286
16.479371
10.090336
2.255436
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5.336273
0.16365
3.395879
1.436792
797.33622
19.509861
17.048969
17.048969
13.58052
10.172671
10.172671
8.175781
8.175781
5.552009
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4.091117
4.091117
-2.19
3,910,707.304521
19.140577
8.445247
4.441991
166.328691
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5.948339
0
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14.148812
0
5.098682
10.197364
12.15204
24.825916
65.540758
12.803726
4.736863
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0
29.444858
12.965578
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50.837456
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4.89991
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75.382404
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24.732415
24.545727
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64.24
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5.917906
81.812424
6.420822
0
24.123162
43.165637
4.736863
9.563731
0
4.926773
13.337554
2.251271
2.63146
0
5.857696
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1.935247
0.65
28
0
8
0
2
2
0
0
2
2
1
0
8
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8
4
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5.773104
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1.337
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1
O=C1CC[C@H](N2C(=O)C3=C[C@@H]4O[C@@H]4C=C3C2=O)C(=O)N1
12.316066
12.316066
0.124924
-0.905236
0.478091
35.2
274.232
264.152
274.058971
102
0
0.261564
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0.360649
0.261564
1.05
1.65
2.2
16.595154
10.00253
2.510551
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6.262313
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3.127125
1.685051
611.146956
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10.28942
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9.558551
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5.173205
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3.933695
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2.848725
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76,946.041598
11.538697
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11.814359
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29.394847
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18.572862
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46.778402
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12.841643
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96.08
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30.956756
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12.15204
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5.316789
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48.551668
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0.384615
20
1
7
1
3
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4
0
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5
1
7
3
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3
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2.096491
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CCOC(=O)[C@H](C)[C@@H](C)NC(=O)CCc1c(C)nc2c(C#N)cnn2c1C
12.299214
12.299214
0.142848
-0.413087
0.744054
13.037037
371.441
346.241
371.19574
144
0
0.310214
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1.37037
2.074074
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16.532935
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5.783597
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3.033533
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896.862669
20.137464
16.36697
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12.794131
8.995553
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6.563548
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4.728167
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2.919131
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891,309.56007
20.362987
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10.053652
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5.969305
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0
46.602959
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18.721632
14.325937
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53.50217
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6.069221
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39.123266
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5.647177
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109.38
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9.589074
0
24.339147
24.238332
16.951307
6.196844
25.286609
13.847474
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9.998755
6.617334
0
28.533778
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3.512658
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9.35327
0
0.526316
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6.503622
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1.85432
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1
O=C(CCBr)N1CCN(C(=O)CCBr)CC1
11.585321
11.585321
0.170801
0.170801
0.711435
16.375
356.058
339.93
353.957852
92
0
0.22303
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0.22303
0.8125
1.125
1.375
79.91976
10.240985
2.224013
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2.064611
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9.090338
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2.297548
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227.203584
11.966255
9.123707
12.2957
7.685071
5.362002
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3.639538
5.225534
2.601795
3.394793
1.683146
2.361526
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3,905.831839
13.962893
7.269587
4.049472
112.595706
9.799819
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11.814359
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31.859888
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49.680848
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9.589074
43.674247
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9.799819
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12.841643
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31.859888
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12.841643
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40.62
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11.814359
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9.799819
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6.509972
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0.341603
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1.0741
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0.8
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6.344029
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1.2272
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1
CCN(CC)C(=O)Nc1ccc(OC[C@@H](O)CNC(C)(C)C)c(C(C)=O)c1
12.16735
12.16735
0.064001
-0.702705
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12.407407
379.501
346.237
379.247107
152
0
0.321319
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1.222222
1.851852
2.37037
16.489979
10.095593
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5.987965
0.094994
2.586326
2.787158
636.604261
20.61252
17.257
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12.567899
9.337606
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7.465296
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3.960023
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2.390981
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438,030.538681
22.920193
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161.630974
25.376877
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6.031115
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0
0
0
59.741524
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19.432465
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10.216698
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53.185315
31.55794
23.762553
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5.749512
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0
59.704839
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51.900412
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90.9
6.103966
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23.960167
36.634619
0
6.923737
23.099011
34.618686
10.633577
4.736863
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25.790904
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12.939516
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0.6
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3
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8.722639
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2.8907
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CC(C(=O)NCCCNc1cnc(C#N)cn1)=C1CCCC1
11.991368
11.991368
0.050986
0.050986
0.620214
13.545455
299.378
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299.17461
116
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0.24637
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1.272727
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3.789649
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2.453742
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140,588.660225
15.959283
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130.208396
10.633577
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4.794537
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0
5.573105
39.027845
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39.027845
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6.069221
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0
28.96465
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11.331113
44.721773
23.539896
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0
0
90.7
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4.794537
0
5.90718
24.601304
24.835569
30.808435
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12.992959
20.601534
5.261892
0
0
19.992911
14.688692
2.500128
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0.5
22
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1
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5
2
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1
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5.896091
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2.15698
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1
CCO/N=C(\C(=O)N[C@@H]1C(=O)N2C(C(=O)O)=C(Sc3nc(-c4cc[n+](C)cc4)cs3)CS[C@H]12)c1nsc(NP(=O)(O)O)n1
13.174098
13.174098
0.084334
-4.673597
0.06302
18.651163
685.708
663.532
685.017557
226
0
0.428874
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0.476538
0.428874
1.302326
2.046512
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CC(C)(C)OC(=O)NCC(C)(C)C(=O)N[C@H]1C[C@H]2CC[C@@H](C1)N2C(=O)CCC#N
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O=C(O)c1ccccc1Nc1cccc(C(F)(F)F)c1
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CCCCCCCC/C=C/CCCCCCCC(=O)O
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CCC1(CC)[C@H](NC(=O)C(=O)Nc2nn(-c3ccc(C#N)cn3)cc2C)[C@H](C)[C@H]1OC
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C=CCN(CC=C)[C@H](CNC(=O)C(=O)NC[C@H]1CN(C)CCN1C)C(C)C
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C[C@@H](N)Cc1ccc(O)c(O)c1
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Cc1ccc(N2CCOC[C@]3(CC(=O)N(CCCC#N)C3)C2)c(C)c1
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COc1ccc2c3c1O[C@@H]1[C@@H](O)CC[C@H]4[C@@H](C2)NCC[C@]314
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CCn1cc(C(=O)N2CCC[C@@H]([C@@H]3CCN(CC#N)C3)C2)c(C)n1
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C=CCn1c(-c2cnccn2)nnc1S(=O)(=O)CCOCCOC
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