While there are important new insights provided by this work, the manuscript can be improved in terms of data presentation and referencing the existing literature on the IFITM proteins.
The largest concern is regarding the colocalization of IFITM3 and Rab11A. It seems (as the authors state) that these represent abortive events (Figure 7). Therefore the inclusion of the movie examining the colocalization of Rab11A GFP, IFITM3-SNAP, and labeled virion seems completely unnecessary. In addition, the movie does not provide any details on cellular features and a viewer is left wondering where the foci are coming from and going. This reviewer suggests removing the movie or alternatively including labels on the movie of cellular features and including a scale bar.