The result must be shown for at least each ESC cell culture (each culture or patient named separately) obtained from each patient to demonstrate that the described results are representative of multiple patients, and not potentially atypical results from an atypical patient.
Lines 142-3. “Data of cell culture are expressed as the mean ± SD from three independent experiments with at least repeated two times.” Change to: Data of cell culture are expressed as the mean ± SD from three independent experiments. All reported results were observed in at least two independent experiments.