We agree with the reviewer that useful tools and techniques are available in different modalities and certainly surgeons dealing with various tumors utilize these as needed. We are fortunate to have access to this multi-modality image guided operating suite, and here we report on its use in specific rare tumors, chordomas and chondrosarcomas. We agree that the use of the PET-CT has no use in these cases, and we mentioned it only as part of the general introduction of the AMIGO suite. We addended the manuscript (line 260-264) as recommended
Intraoperative angiography might have been used in the case of vascular injury but this also is available in many institutions.