The authors´answer regarding the cut off is sufficient, please include this argument either in the methods section or as supplementary information.
[3] Throughout the paper, 10^x wrongly displays as 10x (e.g. "105" instead of "10^5" in lines 152 and 170, "106" instead of "10^6" in line 217, "X2" instead of "X^2" in line 241, "108" instead of "10^8" in lines 353, 354, 365, 366, 367, 368, 370, 371).