This manuscript describes a cohort randomized crossover design comparing cutaneous heat pain ratings and brain activity during heat stimuli after conditions of quiet rest and cycling in patients with a physician-confirmed diagnosis of Fibromyalgia (FM) and age and sex matched controls.
However, the authors need to compare their findings to other research evidence showing impaired EIH and/or descending inhibition in patients with FM - especially considering that their results did not support EIH in the controls.