New discussion regarding the need for PGRMC1 knockout studies to clarify the role of PGRMC1 in decidualization has been inserted in page 9, lines 281-282.
24) The discussion must qualify the results of Salsano et al. who used AG-205 to inhibit PGRMC1. There was no control in PGRMC1 genomic/CRISPR KO cells (not si/miRNA KO) to demonstrate that effects induced by AG-205 were due to PGRMC1.