The observed fluctuations of the membrane do not destabilize it.
This manuscript described the measurement of bending elasticity of giant vesicles (GVs) prepared by archaea-derived lipids. Stroboscopic illumination measurements of GVs and theoretical models about shape fluctuation of GVs revealed that the archaeal lipid-based GVs showed the almost same value of bending elasticity modulus with synthetic lipid-based GVs. According to the authors, this is the first report for the measurement of bending elasticity modulus for archaeal lipid-based GVs. The measurement itself is novel, but same methods and theories have been reported in the authors’ previous papers. In addition, the number of tables and figures are too low for article. If could, the author should add other experimental data.