*p < 0.05, **p < 0.01, ***p < 0.001, and ****p < 0.0001 relative to time-respective control; two-way ANOVA.
Finally, adding to all the above questions, I found a very weak Discussion section which must be extended. Moreover, in the Discussion section, the authors concluded that “TTFields display efficacy for treatment of HCC in vitro and in vivo, with an optimal frequency of 150 kHz”. This is not a correct statement. While for in vitro data, the authors have data, for in vivo they used only one frequency of 150 Hz. At least one different dose should have been studied for comparison since this is a completely different tumor environment than the in vitro one.