The manuscript is very well written, clear and well discussed; I have just few comments: in the Introduction in the sentence 61-69 the authors do not mention anything about BRCA1 (they mention MLH1 though); I would expect that as BRCA1 splice variants are deeply studied.
Lines 342-359 – This paragraph discusses two RAD51C variants, c.404+3A>G and c.705+3A>G, for which mg-FL transcripts were detected in 26.3% and 21.3% or transcripts, respectively.