However, the comment of the reviewer is notable and we state in the conclusion of the manuscript (Lines 229–232) that at room temperature the thermophilicity is not necessarily related to the bending elasticity.
As a comparison of archaeal lipids, SOPC was used in this study. SOPC contains an unsaturated bond in its alkyl chains and its transition temperature seems to be quite low compared with archaeal lipids. What is the reason why the authors selected the SOPC for the representative of eukaryotic lipids?