We thank the reviewer for the positive review.
This is an interesting scientific study, as it concerns the issue of hepatocellular carcinoma, it also has a clinical aspect. The materials and methods section are elaborated in the details. Therefore, I expect further additional examination in the future. References contain mostly publications printed in the last 10 years. The authors indicated that TTFields had potential to be a new treatment option of hepatocellular carcinoma. The present study was examined in terms of autophagy and apoptosis in the antitumor effects of TTFields and sorafenib. However, the exact mechanism of the combination therapy induced cell death is not yet known as the activation of autophagy in the combination therapy was not increased.