(A) Boxplots showing various scores based on high and low NR2F1 expression in HER2 positive breast cancer of TCGA; Intratumoral heterogeneity, homologous recombination deficiency (HRD), silent/non- silent mutation rate, SNV/Indel neoantigen, Interferon gamma response, fraction altered, tumor-infiltrating lymphocytes (TIL) fraction, and stromal fraction.
Moreover, the authors need to provide some, at least minimum, evidence or clues that CAF-expressed NR2F1 is responsible for tumor dormancy regulation.