The author prefers the present title, because the paper is concerned with the origin of the genetic machinery. Theories on the origin of life or on other aspects of early evolution, such as cellularization, serve merely as starting points.  In the introduction the term “or proteins” has been added after “RNA” ,  and the term “retrodict” has been defined.  The term “interpolate” has been clarified.  The problem of mutational saturation is now included in the discussion of Figure 1.  The term “multiply impaired” has been replaced by a clearer wording.  LUCA is discussed only in Section 1.  The protein cycle is discussed in a separate Section 4, which is concerned with the course of evolution before LUCA.
Line 406. “LUCA protein cycle”. Why bring LUCA to a link with the proposed “protein cycle”. LUCA is just the last of a chain of ancestor of diversified life. If the protein cycle requires a coupling of the enthalpic activation of amino acids and the entropic biosynthetic action of a primordial ribosome, then perhaps it is better to call it “ribocellular protein cycle”, since this coupling marks the start of modern cells, not necessarily “modern diversified cells” (i.e., LUCA).