Now we added a sentence of “Moreover, the pathway analysis revealed endometrial cancer and estrogen signaling pathways associated with this cancer (P < 0.05) using the KEGG” in the abstract as the reviewer’s suggestion. In addition, in the introduction section, we added “We are aware of the limited number of cases and lack of control group. Thus future a large study with a control sample and more cases as methodological alternative is needed”. (Please see page 3) Minor comments: 1-
The only real statistical inference they show is on the pathway analysis yet no mention is made on the abstract. I suggest bringing this result up to the surface and making it more relevant even from the abstract. You can refer to it as methodological alternative, in the introduction, for the limited number of cases and lack of control group; issues that must be tackle in a larger study.