We have included explanations of these acronyms in text and Table 1 and have modified the following sentence: “Of the 19 characterized transcripts, 14 introduced premature termination codons (PTC; PTC transcripts), and of these, 10 are predicted to be degraded by the Nonsense-Mediated Decay pathway (NMD; PTC-NMD transcripts) that is considered convincing evidence of deleteriousness (Supplementary Table S3).
The acronyms need to be explained. Not all readers are familiar with PTC (premature termination codon) and NMD (nonsense mediated decay); as some variants are found PTC-NMD, this needs to be explained better. I would also stress a little more that FL is almost undetectable.