Therefore, the authors pointed out that validation and confirmation of the results in a large sample size will be needed in the future.
I missed a definition of the sample's ancestry. In the title it refers to Mexican American but in the rest of the manuscript it is treated as a latino population. Note that there are differences in admixture in the latino population depending of their country of origin. Studies on the 1000 genomes show differences between Puerto Ricans, Colombians, Mexicans and Peruvians. Therefore, if the authors can state that their sample is essentially Mexican that would be more informative and precise. I would then limit the use of latino. However if the ancestry is only self reported as latino, then I would write latino in the title and mention the issue of genetic variability between latinos in the discussion.