All experiments were repeated at least two times. We have failed the description regarding the reproducible results in the previously submitted manuscript, and so revised the section of the methods in the revised manuscript (Page 4, lins143-143).
Additionally, the methods do not say that all results were repeated at least once, and that a representative results figure is presented. Therefore, the reviewer assumes that experiments have only been performed once. The entire set of experiments needs to be replicated to demonstrate reproducibility before it can be considered to publish these results.