I have only a few comments, which might improve the manuscript.
Section 1. The place of RNA in LUCA (page 2): In search of features that are more conserved (carrying deep phylogenetic memory) than the sequence of genes, Wächtershäuser focuses on a paper of his in Systematic and Applied Microbiology (1998) that uses gene content and order of microbial genomes to make inferences about the last universal common ancestor (LUCA) of cellular life. He then mines the significance of some of the conserved chromosomal segments in light of some other evidence. The exercise is at places compelling, but forgets some recent, very global and exhaustive analyses that also use highly conserved biological features to reconstruct the makeup of LUCA (e.g., gene order, 3D molecular structure, molecular functions). See for example PubMed references PMID: 17370266, PMID: 21612591, and PMID: 17908824, which are in line with some conclusions derived from the alignment of Figure 1. The fact that these other analyses make use of hundreds of genomes to infer the ancient biochemistry of LUCA complements and strengthens the preliminary and fragmentary analysis of only 19 of them by the author, which also excludes eukaryotic genomes from the set (understandably, few sequenced genomes were available in 1998, and eukaryotes are in general “master rearrangers”).