As you pointed out, we did not explain the relationship between PGRMC1 stability and post-transcriptional regulation of the protein. We have added the following description (page 9, lines 304-308). ”These reports suggested that PGRMC1 protein levels can be modulated by changes in the rates of transcription, translation, and degradation. Therefore, further studies would be needed to clarify the possible involvement of the post-translational modification and degradation that may regulate PGRMC1 protein stability in ESCs during decidualization.”
In response the authors have made minimal changes to the manuscript, effectively restricted to rewording the title, and several minor text changes.