Ichthyosis with confetti Ichthyosis with confetti Ichthyosis en confetti, also known as ichthyosis with confetti, congenital reticular ichthyosiform erythroderma (CRIE) and ichthyosis variegata, is a very rare form of congenital ichthyosis in which healthy patches of normal skin co-exist within the abnormal skin areas. The condition is caused by a frameshift mutation in the keratin 10 gene (KRT10); mutant keratin 10 accumulates in the nucleolus, a sub-nuclear structure, rather than within cellular intermedite filaments like the wild-type protein. Children with the condition exhibit red, flaky skin; however, for reasons not yet totally clear, wild type clonal patches of skin start to appear, in
Henneke horse body condition scoring system before the race due to their high exercise levels, possibly also leading to a decrease in muscle mass. They explain the differences of results between the studies in part in that the participating horses of the 1990 Purina Race of Champions have had to qualify before and present a more highly-performing field of horses. Both Tevis Cup studies found that horses with a higher body condition score had, however, a significantly higher rate of not finishing the race due to lameness. Horses on pasture should enter the winter season at a body condition score of 6 or 7. On extremely