Harlequin-type ichthyosis describe. It lived about forty-eight hours and was alive when I saw it." The "harlequin-type" designation comes from the diamond shape of the scales at birth (resembling the costume of Arlecchino). Harlequin-type ichthyosis Harlequin-type ichthyosis is a genetic disorder which results in thickened skin over nearly the entire body at birth. The skin forms large, diamond-shaped plates that are separated by deep cracks. They affect the shape of the eyelids, nose, mouth, and ears, and limit movement of the arms and legs. Restricted movement of the chest can lead to breathing difficulties. These plates fall off over several weeks. Other
Medical device manufacturing Medical device manufacturing Medical device manufacturing, as the name suggests, refers to the production of medical devices. Due to the large amount of regulations in the industry, the production of medical devices presents significant challenges from both engineering and legal perspectives. Medical devices are defined by the US Food and Drug Administration (FDA) as any object or component used in diagnosis, treatment, prevention, or cure of medical conditions or diseases, or affects body structure or function through means other than chemical or metabolic reaction in humans or animals. This includes all medical tools, excluding drugs, ranging from tongue depressors to