Harlequin-type ichthyosis condition are extremely sensitive to changes in temperature due to their hard cracked skin, which prevents normal heat loss. Respiration is also restricted by the skin, which impedes the chest wall from expanding and drawing in enough air. This can lead to hypoventilation and respiratory failure. Patients are often dehydrated, as their plated skin is not well suited to retaining water. The diagnosis of harlequin-type ichthyosis relies on both physical examination and certain laboratory tests. Physical assessment at birth is vital for the initial diagnosis of harlequin ichthyosis. Physical examination reveals characteristic symptoms of the condition especially the abnormalities in
The Body in Question The Body in Question The Body in Question is a British-based, internationally co-produced medical television series first aired in the UK in November 1978. This is a 13-part series (1 hour episodes) on all aspects of medicine and health science, written and presented by Dr Jonathan Miller. Miller considers the functioning of the body as a subject of private experience. He explores our attitudes towards our bodies, our ignorance of them, and our inability to read our body's signals. The first episode starts with vox populi asking where various organs in the body are located. By the final episode we