X-linked ichthyosis X-linked ichthyosis X-linked ichthyosis (XLI) (also known as ") is a skin condition caused by the hereditary deficiency of the steroid sulfatase (STS) enzyme that affects 1 in 2000 to 1 in 6000 males. XLI manifests with dry, scaly skin and is due to deletions or mutations in the "STS" gene. XLI can also occur in the context of larger deletions causing contiguous gene syndromes. Treatment is largely aimed at alleviating the skin symptoms. The term is from the Ancient Greek 'ichthys' meaning 'fish'. The major symptoms of XLI include scaling of the skin, particularly on the neck, trunk, and
Sound Affects 1980. In the U.S., the album spent 11 weeks on the "Billboard 200" album charts and reached its peak position of No. 72 in February 1981. The 2010 rerelease also charted in the UK, reaching No. 63 in November of that year. "Sound Affects" was re-issued on 8 November 2010 as a 2 CD Deluxe Edition to celebrate its 30th Anniversary. All songs by Paul Weller except where stated Note ♠ – Tracks previously unreleased Sound Affects Sound Affects is the fifth studio album by British rock band the Jam. The cover art is a pastiche of the artwork used