Ciliary body melanoma appropriate in selected cases. Ciliary body melanoma Ciliary Body Melanoma is a type of cancer arising from the coloured part (uvea) of the eye. About 12% of uveal melanoma arise from the ciliary body. It occurs most commonly in the sixth decade. The tumour is usually diagnosed by clinical examination with a slit-lamp utilising a triple mirror contact lens. Ultrasonography and fine needle aspiration biopsy (FNAB) are also sometimes helpful in confirming the diagnosis. Enucleation (surgical removal of the eye) is the treatment of choice for large ciliary body melanomas. Small or medium sized tumors may be treated by an
Prostaglandin F receptor the Three prime untranslated region of the FP gene to repress its translation. miR-590-3p thus appears to be a negative regulator of FP expression in various cell types. In humans, FP mRNA and/or protein is highly expressed in the uterine myometrium; throughout the eye (endothelium and smooth muscle cells of blood vessels of the iris, ciliary body and choroid plexus; ciliary muscle (circular muscle, collagenous connective tissues; sclera; and ovarian (follicles and corpus luteum). Studies in mice indicate that FP mRNA and/or protein is expressed in diverse tissues including the kidney (distal tubules), uterus, and ovary (Luteal cells of corpus