Harlequin-type ichthyosis Harlequin-type ichthyosis Harlequin-type ichthyosis is a genetic disorder which results in thickened skin over nearly the entire body at birth. The skin forms large, diamond-shaped plates that are separated by deep cracks. They affect the shape of the eyelids, nose, mouth, and ears, and limit movement of the arms and legs. Restricted movement of the chest can lead to breathing difficulties. These plates fall off over several weeks. Other complications can include premature birth, infection, problems with body temperature, and dehydration. Harlequin-type ichthyosis is due to mutations of the "ABCA12" genes. It is inherited from a person's parents in an
Henneke horse body condition scoring system strenuous work and also may lack lean muscle. Horses with a very high body condition score carry too much weight, which interferes with stamina and biomechanics. Some studies addressed the relationship of body condition score and endurance performance in endurance races. In a study of the 1990 Purina Race of Champions (a 241-km / 150-mile, 2-day endurance race), it was found that the top-7 finishers of the race (i.e. highly competitive horses) had significantly lower body condition scores and marginally less rump fat than horses eliminated for metabolic criteria (i.e. less competitive horses). By contrast, two studies on the Tevis