Ichthyosis with confetti Ichthyosis with confetti Ichthyosis en confetti, also known as ichthyosis with confetti, congenital reticular ichthyosiform erythroderma (CRIE) and ichthyosis variegata, is a very rare form of congenital ichthyosis in which healthy patches of normal skin co-exist within the abnormal skin areas. The condition is caused by a frameshift mutation in the keratin 10 gene (KRT10); mutant keratin 10 accumulates in the nucleolus, a sub-nuclear structure, rather than within cellular intermedite filaments like the wild-type protein. Children with the condition exhibit red, flaky skin; however, for reasons not yet totally clear, wild type clonal patches of skin start to appear, in
Sociology of the body such as anorexia and bulimia, and on the other end, there is a growing epidemic of obesity, especially in the US. Both ideals have increased widely over the last few decades due in part to growing mass media coverage in which there are norms within society and the always growing pressure to either look and feel a certain way. Sociology of the body Sociology of the body is a branch of sociology studying the representations and social uses of the human body in modern societies. According to Thomas Laqueur, prior to the eighteenth century the predominant model for a social