Diktyoma mitotic activity, sarcomatous components, or invasion into the uvea, cornea, or sclera. Most diktyomas are malignant. The most common symptoms of diktyoma are vision loss and pain, while the most common signs are leukocoria and presence of a mass in the iris or ciliary body. Other signs and symptoms include lens subluxation, glaucoma, cataract, exophthalmos, buphthalmos, strabismus, and ptosis. Imaging studies such as ultrasonography (US), Computerized Tomography (CT) and Magnetic Resonance Imaging (MRI) may aid diagnosis. On ultrasound, diktyomas typically appear as echogenic, irregularly shaped to ovoid masses. Ultrasound is excellent for demonstrating cystic collections of vitreous fluid in the
Iris pigment epithelium which contributes to the photophobia of that condition. However, diseases specific to the IPE itself are almost non-existent, and it seems to be a highly differentiated, stable cell type that almost never gives rise to malignancies, unlike the melanocytes of the iris stroma. Reports of adenomas and adenocarcinomas of the IPE exist, but some of these are debatable. Iris pigment epithelium The iris pigment epithelium (IPE) is a one cell thick layer of cuboidal cells lying behind the iris. The epithelial cells are highly pigmented due to the numerous large melanosomes which pack the cytoplasm of each cell. Towards the