On the Origin of Species wrote to Murray in confirmation, and listed headings of the 12 chapters in progress: he had drafted all except "XII. Recapitulation & Conclusion". Murray responded immediately with an agreement to publish the book on the same terms as he published Lyell, without even seeing the manuscript: he offered Darwin of the profits. Darwin promptly accepted with pleasure, insisting that Murray would be free to withdraw the offer if, having read the chapter manuscripts, he felt the book would not sell well. (eventually Murray paid £180 to Darwin for the 1st edition and by Darwin's death in 1882 the book was
Genetics and the Origin of Species variation would allow populations to evolve rapidly as environmental conditions change. This book was a landmark in the evolutionary synthesis, as it presented the union of Mendelian genetics and Darwinian theory. In "Genetics and the Origin of Species", polyploidy is considered as a type of mutation. Polyploid cells have a chromosome number that is more than twice the haploid number. The effects of polyploidy between two different species causes hybridization and even greater evolution. Natural selection in an environment produces reproductive success, which benefits the species. Speciation is a process of evolution through which new biological species are formed. Dobzhansky