Harlequin-type ichthyosis condition are extremely sensitive to changes in temperature due to their hard cracked skin, which prevents normal heat loss. Respiration is also restricted by the skin, which impedes the chest wall from expanding and drawing in enough air. This can lead to hypoventilation and respiratory failure. Patients are often dehydrated, as their plated skin is not well suited to retaining water. The diagnosis of harlequin-type ichthyosis relies on both physical examination and certain laboratory tests. Physical assessment at birth is vital for the initial diagnosis of harlequin ichthyosis. Physical examination reveals characteristic symptoms of the condition especially the abnormalities in
Supernumerary body part and two legs. People with this condition often wish to amputate what they see as additional body parts. A phantom limb is the sensation that a missing limb is still attached to the body. A supernumerary phantom limb is the sensation of having an extra limb or body part despite no such limb actually existing. It is an uncommon syndrome, usually due to some kind of brain injuries in the somatosensory cortex or in some parts of the right hemisphere of the brain, usually due to a stroke in the brain. A chimera is an animal or plant that has