Harlequin-type ichthyosis Harlequin-type ichthyosis Harlequin-type ichthyosis is a genetic disorder which results in thickened skin over nearly the entire body at birth. The skin forms large, diamond-shaped plates that are separated by deep cracks. They affect the shape of the eyelids, nose, mouth, and ears, and limit movement of the arms and legs. Restricted movement of the chest can lead to breathing difficulties. These plates fall off over several weeks. Other complications can include premature birth, infection, problems with body temperature, and dehydration. Harlequin-type ichthyosis is due to mutations of the "ABCA12" genes. It is inherited from a person's parents in an
How the Lack of Love Affects Two Men a turn when a divorced woman, Oh Mi-mi, rents a room in their house. Both fall in love with her, and they turn on each other to win her heart. "How the Lack of Love Affects Two Men" was released in South Korea on 16 November 2006, and on its opening weekend topped the box office with 179,489 admissions. The film went on to receive a total of 593,277 admissions nationwide, with a gross (as of 26 November 2006) of $2,470,615. How the Lack of Love Affects Two Men How the Lack of Love Affects Two Men () is a