Ichthyosis with confetti Ichthyosis with confetti Ichthyosis en confetti, also known as ichthyosis with confetti, congenital reticular ichthyosiform erythroderma (CRIE) and ichthyosis variegata, is a very rare form of congenital ichthyosis in which healthy patches of normal skin co-exist within the abnormal skin areas. The condition is caused by a frameshift mutation in the keratin 10 gene (KRT10); mutant keratin 10 accumulates in the nucleolus, a sub-nuclear structure, rather than within cellular intermedite filaments like the wild-type protein. Children with the condition exhibit red, flaky skin; however, for reasons not yet totally clear, wild type clonal patches of skin start to appear, in
Henneke horse body condition scoring system to either being overweight or underweight, respectively. Breeding mares with a body condition score less than five have been linked in research to problems with reproduction. The energy demands of milk production for a foal are very high, so most mares will lose condition while lactating. Also, a mare with a body condition score less than five will have more difficulty conceiving. For these reasons, recommendations are for breeding mares to score between 6 and 7. Higher body condition scores have not been shown to affect reproduction but are unhealthy for the horse. Stallions have the best reproductive success at