Ichthyosis vulgaris is converted to filaggrin which plays a vital role in the structure of the skin). Around 10% of the population have some detrimental mutations to the profilaggrin gene that is also linked to atopic dermatitis (another skin disorder that is often present with ichthyosis vulgaris). The exact mutation is only known for some cases of ichthyosis vulgaris. It is generally considered to be an autosomal dominant condition, i.e., a single genetic mutation causes the disease and an affected person has a 50% chance of passing the condition on to their child. There is some research indicating it may be semi-dominant.
Sound Affects 1980. In the U.S., the album spent 11 weeks on the "Billboard 200" album charts and reached its peak position of No. 72 in February 1981. The 2010 rerelease also charted in the UK, reaching No. 63 in November of that year. "Sound Affects" was re-issued on 8 November 2010 as a 2 CD Deluxe Edition to celebrate its 30th Anniversary. All songs by Paul Weller except where stated Note ♠ – Tracks previously unreleased Sound Affects Sound Affects is the fifth studio album by British rock band the Jam. The cover art is a pastiche of the artwork used