Ichthyosis bullosa of Siemens given by genetic testing. There is no cure for IBS but in the future gene therapy may offer a cure. Treatments for IBS generally attempt to improve the appearance of the skin and the comfort of the sufferer. This is done by exfoliating and increasing the moisture of the skin. Common treatments include: Ichthyosis bullosa of Siemens (IBS) was first described by the German dermatologist Hermann Werner Siemens in 1937 from his study of an affected family. In 1994 the gene causing IBS was discovered and it was also proved in the same year that ichthyosis exfoliativa is the same
Ichthyosis hystrix gene. It is named after Helen Ollendorff Curth (1899-1982), a German-Jewish dermatologist, and Madge Thurlow Macklin (1893–1962), an American medical geneticist, and is one of the first syndromes named after two women. Also known as ichthyosis hystrix gravior or porcupine man. This disease is characterised by spiny scales which cover the entire body except the face, genitals, palms and soles. The only known cases were in Edward Lambert (known as the porcupine man) who was exhibited in front of the Royal Society in London in 1731 and three generations of his descendants. No cases of this disease are now known