Human eye layer, known as the fibrous tunic, is composed of the cornea and sclera. The middle layer, known as the vascular tunic or uvea, consists of the choroid, ciliary body, pigmented epithelium and iris. The innermost is the retina, which gets its oxygenation from the blood vessels of the choroid (posteriorly) as well as the retinal vessels (anteriorly). The spaces of the eye are filled with the aqueous humour anteriorly, between the cornea and lens, and the vitreous body, a jelly-like substance, behind the lens, filling the entire posterior cavity. The aqueous humour is a clear watery fluid that is contained
Iris pigment epithelium which contributes to the photophobia of that condition. However, diseases specific to the IPE itself are almost non-existent, and it seems to be a highly differentiated, stable cell type that almost never gives rise to malignancies, unlike the melanocytes of the iris stroma. Reports of adenomas and adenocarcinomas of the IPE exist, but some of these are debatable. Iris pigment epithelium The iris pigment epithelium (IPE) is a one cell thick layer of cuboidal cells lying behind the iris. The epithelial cells are highly pigmented due to the numerous large melanosomes which pack the cytoplasm of each cell. Towards the