Effects of tightlacing on the body Others believed that every time the bladder or rectum emptied, the uterus was unable to be lifted back into place due to weak ligaments, causing head and back pain, and inability to stand or walk, and improper menstruation. However, this line of thought rested on very little evidence and the assumption that the uterus was one of the most important organs in a woman's body, and it is unlikely that the uterus actually suffered from corsetry. Victorian doctors believed there was a relationship between gallstones and tightlacing, the corset causing extreme weight loss. (Gallstones are the result of the body
History of pain theory or tissue, set up a reverberating, self-exciting loop of activity in a pool of interneurons, and once a threshold of activity is crossed, these interneurons then activate "transmission" cells which carry the signal to the brain's pain mechanism; that the reverberating interneuron activity also spreads to other spinal cord cells that trigger a sympathetic nervous system and somatic motor system response; and these responses, as well as fear and other emotions elicited by pain, feed into and perpetuate the reverberating interneuron activity. A similar proposal was made by RW Gerard in 1951, who proposed also that intense peripheral nerve signalling