Harlequin-type ichthyosis condition are extremely sensitive to changes in temperature due to their hard cracked skin, which prevents normal heat loss. Respiration is also restricted by the skin, which impedes the chest wall from expanding and drawing in enough air. This can lead to hypoventilation and respiratory failure. Patients are often dehydrated, as their plated skin is not well suited to retaining water. The diagnosis of harlequin-type ichthyosis relies on both physical examination and certain laboratory tests. Physical assessment at birth is vital for the initial diagnosis of harlequin ichthyosis. Physical examination reveals characteristic symptoms of the condition especially the abnormalities in
Henneke horse body condition scoring system Cup (a 160-km / 100-mile 24-hour race held each August near Truckee, California) found both for 1995 and 1996 (study 1) and for 1998 (study 2), that significantly more horses finished the race when they had a higher (vs. lower) body condition score: Horses competing in 1995 and 1996 had body condition scores ranging from 1.5 to 5.5 (1998: 2.5 to 5.5); no horses with a score of ≤ 2.5 (1998: scores ≤ 3) finished the respective race, and all horses with a score of 5.5 (same in 1998) finished the respective race. In both studies, no significant relationship was