X-linked ichthyosis X-linked ichthyosis X-linked ichthyosis (XLI) (also known as ") is a skin condition caused by the hereditary deficiency of the steroid sulfatase (STS) enzyme that affects 1 in 2000 to 1 in 6000 males. XLI manifests with dry, scaly skin and is due to deletions or mutations in the "STS" gene. XLI can also occur in the context of larger deletions causing contiguous gene syndromes. Treatment is largely aimed at alleviating the skin symptoms. The term is from the Ancient Greek 'ichthys' meaning 'fish'. The major symptoms of XLI include scaling of the skin, particularly on the neck, trunk, and
Supernumerary body part sometimes represented as having numerous breasts. This was particularly notable in the cult of Artemis (Diana) celebrated in the ancient city of Ephesus, in modern Turkey. In Japanese mythology, the god of the sea and storms, Susanoo, is sometimes depicted as having a third arm. In Hungarian mythology, having six fingers on a hand (polydactyly) is held to be the sign of innate supernatural power (see táltos). In the Bible, Goliath has brothers who have six fingers and six toes. Supernumerary body part Supernumerary body parts are most commonly a congenital disorder involving the growth of an additional part of