Harlequin-type ichthyosis condition are extremely sensitive to changes in temperature due to their hard cracked skin, which prevents normal heat loss. Respiration is also restricted by the skin, which impedes the chest wall from expanding and drawing in enough air. This can lead to hypoventilation and respiratory failure. Patients are often dehydrated, as their plated skin is not well suited to retaining water. The diagnosis of harlequin-type ichthyosis relies on both physical examination and certain laboratory tests. Physical assessment at birth is vital for the initial diagnosis of harlequin ichthyosis. Physical examination reveals characteristic symptoms of the condition especially the abnormalities in
Which Medical Device Which Medical Device Which Medical Device is a review site for medical devices with reviews, medical device news and videos of medical procedures. Users can rate and review medical devices listed on the website, or suggest devices for inclusion and review. The website also publishes device reviews from an editorial team and encourages users to submit detailed reviews. Device manufacturers pay a fee to submit expanded product information to the website. Which Medical Device was launched in September 2010 by Dr Philip Haslam (an Interventional Radiologist based at the Freeman Hospital, Newcastle upon Tyne, United Kingdom) alongside colleague Mr Craig