Harlequin-type ichthyosis condition are extremely sensitive to changes in temperature due to their hard cracked skin, which prevents normal heat loss. Respiration is also restricted by the skin, which impedes the chest wall from expanding and drawing in enough air. This can lead to hypoventilation and respiratory failure. Patients are often dehydrated, as their plated skin is not well suited to retaining water. The diagnosis of harlequin-type ichthyosis relies on both physical examination and certain laboratory tests. Physical assessment at birth is vital for the initial diagnosis of harlequin ichthyosis. Physical examination reveals characteristic symptoms of the condition especially the abnormalities in
Henneke horse body condition scoring system strenuous work and also may lack lean muscle. Horses with a very high body condition score carry too much weight, which interferes with stamina and biomechanics. Some studies addressed the relationship of body condition score and endurance performance in endurance races. In a study of the 1990 Purina Race of Champions (a 241-km / 150-mile, 2-day endurance race), it was found that the top-7 finishers of the race (i.e. highly competitive horses) had significantly lower body condition scores and marginally less rump fat than horses eliminated for metabolic criteria (i.e. less competitive horses). By contrast, two studies on the Tevis