Ichthyosis with confetti Ichthyosis with confetti Ichthyosis en confetti, also known as ichthyosis with confetti, congenital reticular ichthyosiform erythroderma (CRIE) and ichthyosis variegata, is a very rare form of congenital ichthyosis in which healthy patches of normal skin co-exist within the abnormal skin areas. The condition is caused by a frameshift mutation in the keratin 10 gene (KRT10); mutant keratin 10 accumulates in the nucleolus, a sub-nuclear structure, rather than within cellular intermedite filaments like the wild-type protein. Children with the condition exhibit red, flaky skin; however, for reasons not yet totally clear, wild type clonal patches of skin start to appear, in
Kutta condition Kutta condition The Kutta condition is a principle in steady-flow fluid dynamics, especially aerodynamics, that is applicable to solid bodies with sharp corners, such as the trailing edges of airfoils. It is named for German mathematician and aerodynamicist Martin Kutta. Kuethe and Schetzer state the Kutta condition as follows: In fluid flow around a body with a sharp corner, the Kutta condition refers to the flow pattern in which fluid approaches the corner from both directions, meets at the corner, and then flows away from the body. None of the fluid flows around the sharp corner. The Kutta condition is