Ichthyosis documented in some popular breeds of domestic dogs. The most common breeds to have ichthyosis are Golden retrievers, American bulldogs, Jack Russell terriers and Cairn terriers. Ichthyosis Ichthyosis is a family of rare genetic skin disorders characterized by dry, thickened, scaly skin. There are more than 20 types of ichthyosis which range in severity of symptoms, outward appearance, underlying genetic cause and mode of inheritance (e.g., whether the abnormal gene inherited is dominant, recessive, autosomal or X-linked). Ichthyosis comes from the Greek ἰχθύς, ichthys, literally "fish", since dry, scaly skin is the defining feature of all forms of ichthyosis. The
Harlequin-type ichthyosis autosomal recessive manner. Diagnosis is often based on appearance at birth and confirmed by genetic testing. Before birth amniocentesis or ultrasound may support the diagnosis. There is no cure. Early in life constant supportive care is typically required. Treatments may include moisturizing cream, antibiotics, etretinate, or retinoids. It affects about 1 per 300,000 births. Both sexes are affected equally commonly. Long term problems are common. Death in the first month is relatively common. The condition was first documented in 1750. Newborns with harlequin-type ichthyosis present with thick, fissured armor-plate hyperkeratosis. Sufferers feature severe cranial and facial deformities. The ears may