Ichthyosis with confetti Ichthyosis with confetti Ichthyosis en confetti, also known as ichthyosis with confetti, congenital reticular ichthyosiform erythroderma (CRIE) and ichthyosis variegata, is a very rare form of congenital ichthyosis in which healthy patches of normal skin co-exist within the abnormal skin areas. The condition is caused by a frameshift mutation in the keratin 10 gene (KRT10); mutant keratin 10 accumulates in the nucleolus, a sub-nuclear structure, rather than within cellular intermedite filaments like the wild-type protein. Children with the condition exhibit red, flaky skin; however, for reasons not yet totally clear, wild type clonal patches of skin start to appear, in
Sociology of the body of the Structuralist approach in the twentieth century. Especially important within the sociology of the body tradition is the sociology of health and illness. This is because illness may obviously reduce the level of normal functioning of the body. Also, increasingly people in society believe that illness is prevented by fulfilling activities leading to a healthy body (thus changing one's lifestyle) such as dieting and exercise, as well as avoiding anything that can cause damage to the body, like smoking. Moreover, medical science is now able to alter our bodies through plastic surgery, transplanting organs, reproductive aids and even change