Ichthyosis bullosa of Siemens present. A distinctive characteristic of IBS which is not present in other forms of ichthyosis is called the "Mauserung phenomenon" (Mauserung is German for "moulting" and was first described by H.W.Siemens). These are small patches of bare, apparently normal skin in the middle of areas of hyperkeratosis. As the sufferer ages the flaking and blistering should improve. The hyperkeratosis may grow more severe but more localized and is generally only present on flexural folds of the major joints. IBS is an autosomal dominant genetic condition caused by a mutation in the gene for keratin 2e on chromosome 12. This means
The Bringers of Wonder, Part One Koenig, Helena gives as good as she gets. Across the room, Vincent is showing Louisa one of the remote medical relays which allow them to monitor patients from anywhere on the base. He observes Koenig's obvious distress, but Louisa stares into his eyes and he, in a trance-like state, switches off the monitor. When the girl is swept away by Carter, Vincent's head clears. Reactivating the screen, he observes Koenig's condition and dashes from the room. Koenig is convulsing by the time Vincent reaches Medical. He throws the orderly away from the brain complex, but the man attacks him with