Ichthyosis documented in some popular breeds of domestic dogs. The most common breeds to have ichthyosis are Golden retrievers, American bulldogs, Jack Russell terriers and Cairn terriers. Ichthyosis Ichthyosis is a family of rare genetic skin disorders characterized by dry, thickened, scaly skin. There are more than 20 types of ichthyosis which range in severity of symptoms, outward appearance, underlying genetic cause and mode of inheritance (e.g., whether the abnormal gene inherited is dominant, recessive, autosomal or X-linked). Ichthyosis comes from the Greek ἰχθύς, ichthys, literally "fish", since dry, scaly skin is the defining feature of all forms of ichthyosis. The
Estrogen-dependent condition such as tamoxifen and clomifene, estrogen receptor antagonists such as fulvestrant, aromatase inhibitors such as anastrozole and exemestane, gonadotropin-releasing hormone (GnRH) analogues such as leuprorelin and cetrorelix, and/or other antigonadotropins such as danazol, gestrinone, megestrol acetate, and medroxyprogesterone acetate. Estrogen-dependent condition An estrogen-dependent condition, disease, disorder, or syndrome, is a medical condition that is, in part or full, dependent on, or is sensitive to, the presence of estrogenic activity in the body. Known estrogen-dependent conditions include mastodynia (breast pain/tenderness), breast fibroids, mammoplasia (breast enlargement), macromastia (breast hypertrophy), gynecomastia, breast cancer, precocious puberty in girls, melasma, menorrhagia, endometriosis, endometrial hyperplasia, adenomyosis,