Operation (game) amongst the players at the beginning of the game. In the U.S and Australian version, players take turns picking "Doctor" cards, which offer a cash payment for removing each particular ailment, using a pair of tweezers connected with wire to the board. Successfully removing the ailment is rewarded according to the dollar amount shown on the card. However, if the tweezers touch the metal edge of the opening during the attempt (thereby closing a circuit), a buzzer sounds, Sam's nose lights up red, and the player loses the turn. The player holding the "Specialist" card for that piece then has
Molecular tweezers Molecular tweezers Molecular tweezers, and molecular clips, are host molecules with open cavities capable of binding guest molecules. The open cavity of the molecular tweezers may bind guests using non-covalent bonding which includes hydrogen bonding, metal coordination, hydrophobic forces, van der Waals forces, π-π interactions, and/or electrostatic effects. These complexes are a subset of macrocyclic molecular receptors and their structure is that the two "arms" that bind the guest molecule between them are only connected at one end leading to a certain flexibility of these receptor molecules (induced fit model). The term "molecular tweezers" was first used by Whitlock. The