Ichthyosis with confetti Ichthyosis with confetti Ichthyosis en confetti, also known as ichthyosis with confetti, congenital reticular ichthyosiform erythroderma (CRIE) and ichthyosis variegata, is a very rare form of congenital ichthyosis in which healthy patches of normal skin co-exist within the abnormal skin areas. The condition is caused by a frameshift mutation in the keratin 10 gene (KRT10); mutant keratin 10 accumulates in the nucleolus, a sub-nuclear structure, rather than within cellular intermedite filaments like the wild-type protein. Children with the condition exhibit red, flaky skin; however, for reasons not yet totally clear, wild type clonal patches of skin start to appear, in
Henneke horse body condition scoring system for most horses is from 4 to 6. The system is based on both visual appraisal and palpable fat cover of the six major points of the horse. The system is used by law enforcement agencies as an objective method of scoring a horse's body condition in horse cruelty cases. The Henneke scale describes body condition scores as follows: The average horse is healthiest with a body condition score between 5 and 6, which indicate that the horse has a proper balance of feed to exercise. An easy keeper or hard keeper should be watched closely as they are prone