Ciliary body melanoma appropriate in selected cases. Ciliary body melanoma Ciliary Body Melanoma is a type of cancer arising from the coloured part (uvea) of the eye. About 12% of uveal melanoma arise from the ciliary body. It occurs most commonly in the sixth decade. The tumour is usually diagnosed by clinical examination with a slit-lamp utilising a triple mirror contact lens. Ultrasonography and fine needle aspiration biopsy (FNAB) are also sometimes helpful in confirming the diagnosis. Enucleation (surgical removal of the eye) is the treatment of choice for large ciliary body melanomas. Small or medium sized tumors may be treated by an
Iris sphincter muscle reflex) or during accommodation. In lower animals, the muscle cells themselves are photosensitive causing iris action without brain input. It is controlled by parasympathetic fibers of the muscarinic acetylcholine receptor (M3) that originate from the Edinger-Westphal nucleus, travel along the oculomotor nerve (CN III), synapse in the ciliary ganglion, and then enter the eye via the short ciliary nerves.. The short ciliary nerves then run forward and pierce the sclera at the back of the eye, traveling between the sclera and the choroid to innervate the iris sphincter muscle. Iris sphincter muscle The iris sphincter muscle (pupillary sphincter, pupillary constrictor,