Ichthyosis vulgaris is converted to filaggrin which plays a vital role in the structure of the skin). Around 10% of the population have some detrimental mutations to the profilaggrin gene that is also linked to atopic dermatitis (another skin disorder that is often present with ichthyosis vulgaris). The exact mutation is only known for some cases of ichthyosis vulgaris. It is generally considered to be an autosomal dominant condition, i.e., a single genetic mutation causes the disease and an affected person has a 50% chance of passing the condition on to their child. There is some research indicating it may be semi-dominant.
Henneke horse body condition scoring system Cup (a 160-km / 100-mile 24-hour race held each August near Truckee, California) found both for 1995 and 1996 (study 1) and for 1998 (study 2), that significantly more horses finished the race when they had a higher (vs. lower) body condition score: Horses competing in 1995 and 1996 had body condition scores ranging from 1.5 to 5.5 (1998: 2.5 to 5.5); no horses with a score of ≤ 2.5 (1998: scores ≤ 3) finished the respective race, and all horses with a score of 5.5 (same in 1998) finished the respective race. In both studies, no significant relationship was