All Creatures Great and Small (franchise) "James Herriot", and are set in the fictional town of "Darrowby", based on a combination of Thirsk, Richmond, Leyburn and Middleham.. In the books James Herriot work with fellow veterinary surgeons, Siegfried and Tristan Farnon, based on real-life counterparts, "Donald Sinclair" and his brother "Brian Sinclair" respectively. Wight also used the name "Helen Alderson" for his wife, Joan Danbury. In America the books were collected as pairs into omnibus volumes, as the publisher felt they were too short to publish independently. The title chosen for the first book in the series "All Creatures Great and Small" (and subsequently one of
Phenobarbital airway patency (through endotracheal intubation and mechanical ventilation), correction of bradycardia and hypotension (with intravenous fluids and vasopressors, if necessary) and removal of as much drug as possible from the body. Depending on how much time has elapsed since ingestion of the drug, this may be accomplished through gastric lavage (stomach pumping) or use of activated charcoal. Hemodialysis is effective in removing phenobarbital from the body, and may reduce its half-life by up to 90%. No specific antidote for barbiturate poisoning is available. British veterinarian Donald Sinclair, better known as "Siegfried Farnon" in the "All Creatures Great and Small" books