Iris (anatomy) surface projects as the dilator muscles. The high pigment content blocks light from passing through the iris to the retina, restricting it to the pupil. The outer edge of the iris, known as the root, is attached to the sclera and the anterior ciliary body. The iris and ciliary body together are known as the anterior uvea. Just in front of the root of the iris is the region referred to as the trabecular meshwork, through which the aqueous humour constantly drains out of the eye, with the result that diseases of the iris often have important effects on intraocular
Iris pigment epithelium which contributes to the photophobia of that condition. However, diseases specific to the IPE itself are almost non-existent, and it seems to be a highly differentiated, stable cell type that almost never gives rise to malignancies, unlike the melanocytes of the iris stroma. Reports of adenomas and adenocarcinomas of the IPE exist, but some of these are debatable. Iris pigment epithelium The iris pigment epithelium (IPE) is a one cell thick layer of cuboidal cells lying behind the iris. The epithelial cells are highly pigmented due to the numerous large melanosomes which pack the cytoplasm of each cell. Towards the