Ichthyosis bullosa of Siemens present. A distinctive characteristic of IBS which is not present in other forms of ichthyosis is called the "Mauserung phenomenon" (Mauserung is German for "moulting" and was first described by H.W.Siemens). These are small patches of bare, apparently normal skin in the middle of areas of hyperkeratosis. As the sufferer ages the flaking and blistering should improve. The hyperkeratosis may grow more severe but more localized and is generally only present on flexural folds of the major joints. IBS is an autosomal dominant genetic condition caused by a mutation in the gene for keratin 2e on chromosome 12. This means
The Human Condition (Magritte) The Human Condition (Magritte) The Human Condition (La condition humaine) generally refers to two similar oil on canvas paintings by the Belgian surrealist René Magritte. One was completed in 1933 and is in the collection of the National Gallery of Art in Washington DC. The other was completed in 1935 and is part of the Simon Spierer Collection in Geneva, Switzerland. A number of drawings of the same name exist as well, including one at the Cleveland Museum of Art. One of Magritte's most common artistic devices was the use of objects to hide what lies behind them. For example,