Ichthyosis vulgaris is converted to filaggrin which plays a vital role in the structure of the skin). Around 10% of the population have some detrimental mutations to the profilaggrin gene that is also linked to atopic dermatitis (another skin disorder that is often present with ichthyosis vulgaris). The exact mutation is only known for some cases of ichthyosis vulgaris. It is generally considered to be an autosomal dominant condition, i.e., a single genetic mutation causes the disease and an affected person has a 50% chance of passing the condition on to their child. There is some research indicating it may be semi-dominant.
Henneke horse body condition scoring system to either being overweight or underweight, respectively. Breeding mares with a body condition score less than five have been linked in research to problems with reproduction. The energy demands of milk production for a foal are very high, so most mares will lose condition while lactating. Also, a mare with a body condition score less than five will have more difficulty conceiving. For these reasons, recommendations are for breeding mares to score between 6 and 7. Higher body condition scores have not been shown to affect reproduction but are unhealthy for the horse. Stallions have the best reproductive success at