Ichthyosis vulgaris is converted to filaggrin which plays a vital role in the structure of the skin). Around 10% of the population have some detrimental mutations to the profilaggrin gene that is also linked to atopic dermatitis (another skin disorder that is often present with ichthyosis vulgaris). The exact mutation is only known for some cases of ichthyosis vulgaris. It is generally considered to be an autosomal dominant condition, i.e., a single genetic mutation causes the disease and an affected person has a 50% chance of passing the condition on to their child. There is some research indicating it may be semi-dominant.
Association for Improving the Condition of the Poor A. Kingsbury, later on the Commission of Public Charities (1914–1917) and Harry L. Hopkins the future director of President Franklin D. Roosevelt's Works Progress Administration, part of the New Deal. Notes Association for Improving the Condition of the Poor The Association for Improving the Condition of the Poor (AICP) was a charitable organization in New York City, established in 1843 and incorporated in 1848 with the aim of helping the deserving poor and providing for their moral uplift. The Association was one of the most active and innovative charity organizations in New York, pioneering many private-public partnerships in education, healthcare