Harlequin-type ichthyosis Harlequin-type ichthyosis Harlequin-type ichthyosis is a genetic disorder which results in thickened skin over nearly the entire body at birth. The skin forms large, diamond-shaped plates that are separated by deep cracks. They affect the shape of the eyelids, nose, mouth, and ears, and limit movement of the arms and legs. Restricted movement of the chest can lead to breathing difficulties. These plates fall off over several weeks. Other complications can include premature birth, infection, problems with body temperature, and dehydration. Harlequin-type ichthyosis is due to mutations of the "ABCA12" genes. It is inherited from a person's parents in an
The Body in Question The Body in Question The Body in Question is a British-based, internationally co-produced medical television series first aired in the UK in November 1978. This is a 13-part series (1 hour episodes) on all aspects of medicine and health science, written and presented by Dr Jonathan Miller. Miller considers the functioning of the body as a subject of private experience. He explores our attitudes towards our bodies, our ignorance of them, and our inability to read our body's signals. The first episode starts with vox populi asking where various organs in the body are located. By the final episode we