Ichthyosis bullosa of Siemens present. A distinctive characteristic of IBS which is not present in other forms of ichthyosis is called the "Mauserung phenomenon" (Mauserung is German for "moulting" and was first described by H.W.Siemens). These are small patches of bare, apparently normal skin in the middle of areas of hyperkeratosis. As the sufferer ages the flaking and blistering should improve. The hyperkeratosis may grow more severe but more localized and is generally only present on flexural folds of the major joints. IBS is an autosomal dominant genetic condition caused by a mutation in the gene for keratin 2e on chromosome 12. This means
The Body Silent The Body Silent The Body Silent is a personal narrative written by Robert Murphy, a professor at Columbia University. This piece is a narrative of personal struggle through a spinal condition, published in 1987 by Henry Holt and Company, Inc. He uses this narrative to tell his journey through a deteriorating spinal condition leading to paraplegia. He was diagnosed with a tumor extending from his second cervical vertebra to the eighth thoracic vertebra in 1972. Through his narrative he tells his medical history and how the diagnosis of old medicine (late 1920s) knew very little about neurology, and left undetected