Harlequin-type ichthyosis condition are extremely sensitive to changes in temperature due to their hard cracked skin, which prevents normal heat loss. Respiration is also restricted by the skin, which impedes the chest wall from expanding and drawing in enough air. This can lead to hypoventilation and respiratory failure. Patients are often dehydrated, as their plated skin is not well suited to retaining water. The diagnosis of harlequin-type ichthyosis relies on both physical examination and certain laboratory tests. Physical assessment at birth is vital for the initial diagnosis of harlequin ichthyosis. Physical examination reveals characteristic symptoms of the condition especially the abnormalities in
Neuroendocrine carcinoma of the cervix Neuroendocrine carcinoma of the cervix Neuroendocrine carcinoma of the cervix is best defined separately: Neuroendocrine: Of, relating to, or involving the interaction between the nervous system and the hormones of the endocrine glands. Carcinoma: An invasive malignant tumor derived from epithelial tissue that tends to metastasize to other areas of the body. Neuroendocrine carcinoma affects many different parts of the body. In the cervix, it is a rare, but very aggressive form of cervical cancer. In its early stages, neuroendocrine carcinoma is asymptomatic (not showing or producing indications of a disease or other medical condition). In more advanced stages, symptoms