Colonization of the Moon the Soviet leadership made some of its first public pronouncements about landing a man on the Moon and establishing a lunar base. Crewed exploration of the lunar surface began in 1968 when the Apollo 8 spacecraft orbited the Moon with three astronauts on board. This was mankind's first direct view of the far side. The following year, the Apollo 11 Apollo Lunar Module landed two astronauts on the Moon, proving the ability of humans to travel to the Moon, perform scientific research work there, and bring back sample materials. Additional missions to the Moon continued this exploration phase. In 1969,
Effect of spaceflight on the human body Effect of spaceflight on the human body Venturing into the environment of space can have negative effects on the human body. Significant adverse effects of long-term weightlessness include muscle atrophy and deterioration of the skeleton (spaceflight osteopenia). Other significant effects include a slowing of cardiovascular system functions, decreased production of red blood cells, balance disorders, eyesight disorders and a weakening of the immune system. Additional symptoms include fluid redistribution (causing the "moon-face" appearance typical in pictures of astronauts experiencing weightlessness), loss of body mass, nasal congestion, sleep disturbance, and excess flatulence. The engineering problems associated with leaving Earth and developing