Harlequin-type ichthyosis condition are extremely sensitive to changes in temperature due to their hard cracked skin, which prevents normal heat loss. Respiration is also restricted by the skin, which impedes the chest wall from expanding and drawing in enough air. This can lead to hypoventilation and respiratory failure. Patients are often dehydrated, as their plated skin is not well suited to retaining water. The diagnosis of harlequin-type ichthyosis relies on both physical examination and certain laboratory tests. Physical assessment at birth is vital for the initial diagnosis of harlequin ichthyosis. Physical examination reveals characteristic symptoms of the condition especially the abnormalities in
The Human Condition (Magritte) The Human Condition (Magritte) The Human Condition (La condition humaine) generally refers to two similar oil on canvas paintings by the Belgian surrealist René Magritte. One was completed in 1933 and is in the collection of the National Gallery of Art in Washington DC. The other was completed in 1935 and is part of the Simon Spierer Collection in Geneva, Switzerland. A number of drawings of the same name exist as well, including one at the Cleveland Museum of Art. One of Magritte's most common artistic devices was the use of objects to hide what lies behind them. For example,