Uveitis between 28% and 50%. Uveitis is estimated to be responsible for approximately 10%-20% of the blindness in the United States. Uveitis Uveitis is the inflammation of the uvea, the pigmented layer that lies between the inner retina and the outer fibrous layer composed of the sclera and cornea. The uvea consists of the middle layer of pigmented vascular structures of the eye and includes the iris, ciliary body, and choroid. Uveitis is an ophthalmic emergency and requires a thorough examination by an optometrist or ophthalmologist and urgent treatment to control the inflammation. It is often associated with other ocular problems.
Ciliary muscle parasympathetic postganglionic fibers are part of cranial nerve V (Nasociliary nerve of the trigeminal), while presynaptic parasympathetic fibers to the ciliary ganglia are from the oculomotor nerve. The postganglionic sympathetic innervation arises from the superior cervical ganglia. Presynaptic parasympathetic signals that originate in the Edinger-Westphal nucleus are carried by cranial nerve III (the oculomotor nerve) and travel through the ciliary ganglion via the postganglionic parasympathetics fibers which travel in the short ciliary nerves and supply the ciliary body and iris. Parasympathetic activation of the M3 muscarinic receptors causes ciliary muscle contraction, the effect of contraction is to decrease the diameter