CREATE TABLE table_59343 ("DVD Title" TEXT, "No. of Discs" FLOAT, "Year" TEXT, "No. of Episodes" FLOAT, "Region 1" TEXT, "Region 2" TEXT, "Region 4" TEXT)

Which region 1 has 12 Episodes and a Region 2 of 18 August 2008?
SELECT "Region 1" FROM table_59343 WHERE "No. of Episodes" = '12' AND "Region 2" = '18 august 2008'
SELECT "Region 1" FROM "table_59343" WHERE "No. of Episodes" = '12' AND "Region 2" = '18 august 2008'