CREATE TABLE table_train_124 ("id" INT, "loss_of_consciousness" BOOLEAN, "serum_glucose" BOOLEAN, "myelosuppression" BOOLEAN, "retinoids_hepatotoxic" BOOLEAN, "pulmonary_disease" BOOLEAN, "etiology" BOOLEAN, "abnormal_thyroid_function" BOOLEAN, "laboratory_abnormality" BOOLEAN, "chest_pain" BOOLEAN, "dsm_iv_criteria" BOOLEAN, "neurodegenerative_disease" BOOLEAN, "active_infection" BOOLEAN, "epilepsy" BOOLEAN, "major_psychiatric_disorder" BOOLEAN, "investigational_new_drug" BOOLEAN, "head_injury" BOOLEAN, "stroke" BOOLEAN, "substance_dependence" BOOLEAN, "anterograde_amnesia" BOOLEAN, "renal_disease" BOOLEAN, "cerebrovascular_disease" BOOLEAN, "hepatic_disease" BOOLEAN, "other_systemic_disease" BOOLEAN, "psychiatric_disease" BOOLEAN, "clinical_disorder" BOOLEAN, "multiple_sclerosis" BOOLEAN, "retinoids" BOOLEAN, "cardiovascular_disease" BOOLEAN, "hematologic_disease" BOOLEAN, "prothrombin_time" BOOLEAN, "focal_brain_lesion" BOOLEAN, "ventricular_fibrillation" BOOLEAN, "psychosis" BOOLEAN, "liver_disease" BOOLEAN, "bipolar_disorder" BOOLEAN, "chronic_inflammatory" BOOLEAN, "brain_lesions" BOOLEAN, "diabetes" BOOLEAN, "vitamin_b12_deficiency" BOOLEAN, "medical_disorder" BOOLEAN, "total_bilirubin" BOOLEAN, "gastrointestinal_disease" BOOLEAN, "endocrine_disease" BOOLEAN, "metabolic" BOOLEAN, "ventricular_tachycardia" BOOLEAN, "neurological_disease" BOOLEAN, "seizure_disorder" BOOLEAN, "ast_or_alt" BOOLEAN, "alcohol_abuse" BOOLEAN, "ad" BOOLEAN, "neurosurgery" BOOLEAN, "allergy_to_retinoids" BOOLEAN, "brain_radiation" BOOLEAN, "major_depression" BOOLEAN, "NOUSE" FLOAT)

evidence of any significant clinical disorder or laboratory finding that renders the participant unsuitable for receiving an investigational new drug including clinically significant or unstable hematologic, hepatic, cardiovascular ( including history of ventricular fibrillation or ventricular tachycardia ) , pulmonary, gastrointestinal, endocrine, metabolic, renal, or other systemic disease or laboratory abnormality. abnormal liver function test, including ast, alt, total bilirubin, or prothrombin time. the rationale is that retinoids can be hepatotoxic.
SELECT * FROM table_train_124 WHERE clinical_disorder = 1 OR (investigational_new_drug = 1 OR hematologic_disease = 1 OR hepatic_disease = 1 OR (cardiovascular_disease = 1 OR ventricular_fibrillation = 1 OR ventricular_tachycardia = 1) OR pulmonary_disease = 1 OR gastrointestinal_disease = 1 OR endocrine_disease = 1 OR metabolic = 1 OR renal_disease = 1 OR other_systemic_disease = 1 OR laboratory_abnormality = 1 AND (liver_disease = 1 OR ast_or_alt = 1 OR total_bilirubin = 1 OR prothrombin_time = 1 OR retinoids_hepatotoxic = 1))
SELECT * FROM "table_train_124" WHERE ("ast_or_alt" = 1 OR "clinical_disorder" = 1 OR "liver_disease" = 1 OR "prothrombin_time" = 1 OR "retinoids_hepatotoxic" = 1 OR "total_bilirubin" = 1) AND ("cardiovascular_disease" = 1 OR "clinical_disorder" = 1 OR "endocrine_disease" = 1 OR "gastrointestinal_disease" = 1 OR "hematologic_disease" = 1 OR "hepatic_disease" = 1 OR "investigational_new_drug" = 1 OR "laboratory_abnormality" = 1 OR "metabolic" = 1 OR "other_systemic_disease" = 1 OR "pulmonary_disease" = 1 OR "renal_disease" = 1 OR "ventricular_fibrillation" = 1 OR "ventricular_tachycardia" = 1)