CREATE TABLE table_204_386 (id DECIMAL, "res." TEXT, "record" TEXT, "opponent" TEXT, "method" TEXT, "event" TEXT, "date" TEXT, "round" DECIMAL, "time" TEXT, "location" TEXT, "notes" TEXT)

her first loss was against this opponent
SELECT "opponent" FROM table_204_386 WHERE "res." = 'loss' ORDER BY "date" LIMIT 1
SELECT "opponent" FROM "table_204_386" WHERE "res." = 'loss' ORDER BY "date" NULLS FIRST LIMIT 1