CREATE TABLE table_203_589 (id DECIMAL, "protein" TEXT, "natural host" TEXT, "normal function" TEXT, "prion state" TEXT, "prion phenotype" TEXT, "year identified" DECIMAL)

podospora anserina or saccharomyces cerevisiae is the natural host for het s ?
SELECT "natural host" FROM table_203_589 WHERE "natural host" IN ('podospora anserina', 'saccharomyces cerevisiae') AND "protein" = 'het-s'
SELECT "natural host" FROM "table_203_589" WHERE "natural host" IN ('podospora anserina', 'saccharomyces cerevisiae') AND "protein" = 'het-s'