CREATE TABLE enzyme (id DECIMAL, name TEXT, location TEXT, product TEXT, chromosome TEXT, omim DECIMAL, porphyria TEXT)
CREATE TABLE medicine (id DECIMAL, name TEXT, trade_name TEXT, fda_approved TEXT)
CREATE TABLE medicine_enzyme_interaction (enzyme_id DECIMAL, medicine_id DECIMAL, interaction_type TEXT)

What is the count of enzymes without any interactions?
SELECT COUNT(*) FROM enzyme WHERE NOT id IN (SELECT enzyme_id FROM medicine_enzyme_interaction)
SELECT COUNT(*) FROM "enzyme" WHERE NOT "id" IN (SELECT "enzyme_id" FROM "medicine_enzyme_interaction")