CREATE TABLE table_78750 ("Opposing Teams" TEXT, "Against" FLOAT, "Date" TEXT, "Venue" TEXT, "Status" TEXT)

What's the total against for opposing team scotland at twickenham, london venue with a status of five nations?
SELECT COUNT("Against") FROM table_78750 WHERE "Status" = 'five nations' AND "Venue" = 'twickenham, london' AND "Opposing Teams" = 'scotland'
SELECT COUNT("Against") FROM "table_78750" WHERE "Opposing Teams" = 'scotland' AND "Status" = 'five nations' AND "Venue" = 'twickenham, london'