id stringlengths 68 80 | image stringlengths 71 73 | conversations listlengths 2 2 |
|---|---|---|
Morphology_choice_TCGA-X7-A8DJ-01Z-00-DX1.F01AB5E9-7869-4487-912F-8D3EEA9CB187-2 | TCGA-THYM/TCGA-X7-A8DJ-01Z-00-DX1.F01AB5E9-7869-4487-912F-8D3EEA9CB187.pt | [
{
"from": "human",
"value": "<image>\nHow does the tissue architecture of this thymoma appear based on your observations? A) The tumor shows a homogenous pattern without distinct lobulation. B) The tumor exhibits a lobulated growth pattern with a mix of spindle-shaped and round epithelial cells. C) The tumo... |
Prognosis_TF_TCGA-E2-A159-01Z-00-DX1.C8DC3356-CAE9-4E7A-AEFF-ABB4BE38192B-1 | TCGA-BRCA/TCGA-E2-A159-01Z-00-DX1.C8DC3356-CAE9-4E7A-AEFF-ABB4BE38192B.pt | [
{
"from": "human",
"value": "<image>\nGiven the diagnosis of SBR grade 3 invasive ductal carcinoma with necrosis and lymphoid infiltrate, is the prognosis good?"
},
{
"from": "gpt",
"value": "No"
}
] |
MorDetail_TCGA-E2-A15K-01Z-00-DX1.9F424BE2-9BFE-4DFF-8CC9-10D2DADBBEA7-2 | TCGA-BRCA/TCGA-E2-A15K-01Z-00-DX1.9F424BE2-9BFE-4DFF-8CC9-10D2DADBBEA7.pt | [
{
"from": "human",
"value": "<image>\nHow do the glandular structures appear in the tissue?"
},
{
"from": "gpt",
"value": "The glandular structures exhibit minimal formation. The architectural pattern is significantly disrupted with only scant, poorly organized tubular formations present. This i... |
Treatment_TCGA-AR-A24T-01Z-00-DX1.3B325D54-38EC-4E16-BDE1-628894CC15AA-1 | TCGA-BRCA/TCGA-AR-A24T-01Z-00-DX1.3B325D54-38EC-4E16-BDE1-628894CC15AA.pt | [
{
"from": "human",
"value": "<image>\nWhat is the recommended treatment plan for a patient diagnosed with infiltrating lobular carcinoma, Nottingham grade I, TNM staging T3N3M0, with pending HER2 status?"
},
{
"from": "gpt",
"value": "1. Surgery: Typically, a mastectomy or breast-conserving surg... |
MorDetail_TCGA-WK-A8XT-01Z-00-DX1.BA738161-33AA-46F9-8204-81C89548C1A8-1 | TCGA-SARC/TCGA-WK-A8XT-01Z-00-DX1.BA738161-33AA-46F9-8204-81C89548C1A8.pt | [
{
"from": "human",
"value": "<image>\nAre the tumor cells displaying a consistently monomorphic spindle-shaped appearance?"
},
{
"from": "gpt",
"value": "Yes, the tumor cells display a monomorphic spindle-shaped appearance. They are uniform in shape and size, with elongated nuclei and scant cyto... |
MorDetail_TCGA-DA-A1I2-01Z-00-DX1.C1001885-ABFE-47B6-A49A-AD118D4FB619-3 | TCGA-SKCM/TCGA-DA-A1I2-01Z-00-DX1.C1001885-ABFE-47B6-A49A-AD118D4FB619.pt | [
{
"from": "human",
"value": "<image>\nIs there an inflammatory infiltrate surrounding the tumor cells?"
},
{
"from": "gpt",
"value": "Yes, there is an inflammatory infiltrate partially surrounding the tumor cells. This infiltrate consists predominantly of lymphocytes and some plasma cells, indic... |
MorDetail_TCGA-DJ-A1QO-01Z-00-DX1.97439F9B-2A25-4CCF-B478-B27B389F6704-5 | TCGA-THCA/TCGA-DJ-A1QO-01Z-00-DX1.97439F9B-2A25-4CCF-B478-B27B389F6704.pt | [
{
"from": "human",
"value": "<image>\nAre papillary microcarcinomas observed within the thyroid lobes?"
},
{
"from": "gpt",
"value": "Yes, there are two microscopic foci of papillary microcarcinoma identified within the thyroid lobes. These foci are small and consist of tiny clusters of papillar... |
Report_TCGA-91-A4BD-01Z-00-DX1.2E575CAC-6AEB-4049-972A-EA43457A9C9D-1 | TCGA-LUAD/TCGA-91-A4BD-01Z-00-DX1.2E575CAC-6AEB-4049-972A-EA43457A9C9D.pt | [
{
"from": "human",
"value": "<image>\nWhat does the whole slide histopathology image depict, and what is the diagnosis?"
},
{
"from": "gpt",
"value": "Microscopic observation of the pathology slide reveals architectural features characteristic of adenocarcinoma with a lepidic growth pattern, whe... |
Stage_choice_TCGA-DD-AACM-01Z-00-DX1.D184466C-8491-4CC0-8B76-274DBFD97851-1 | TCGA-LIHC/TCGA-DD-AACM-01Z-00-DX1.D184466C-8491-4CC0-8B76-274DBFD97851.pt | [
{
"from": "human",
"value": "<image>\nFor a patient with a tumor measuring 3 cm in size, no regional lymph node involvement, and no distant metastasis, what is their TNM staging? A) T1 N1 M0 B) T2 N0 M0 C) T3 N0 M1 D) T2 N2 M0"
},
{
"from": "gpt",
"value": "B"
}
] |
Morphology_choice_TCGA-DX-A8BT-01Z-00-DX2.6579E6B2-E2D0-406E-87E8-03C46EC3642B-3 | TCGA-SARC/TCGA-DX-A8BT-01Z-00-DX2.6579E6B2-E2D0-406E-87E8-03C46EC3642B.pt | [
{
"from": "human",
"value": "<image>\nWhat are the notable features of the cellular morphology in the observed specimen? A) Cells exhibit slight variability in size and shape with low pleomorphism. B) Cells are uniform in appearance with no signs of significant variation. C) Cells show marked variability in... |
Morphology_choice_TCGA-D1-A1NW-01Z-00-DX1.04B1253F-DDEF-4EF6-828F-402C0DBC75CE-1 | TCGA-UCEC/TCGA-D1-A1NW-01Z-00-DX1.04B1253F-DDEF-4EF6-828F-402C0DBC75CE.pt | [
{
"from": "human",
"value": "<image>\nCan you describe the pattern of tumor infiltration seen in this high-grade serous adenocarcinoma specimen? A) Tumor cells infiltrate the surrounding stroma, with vascular invasion present. B) Tumor cells are confined to the primary site without evidence of serosal invas... |
Conversation_TCGA-CE-A482-01Z-00-DX1.0F46244F-5C28-41EA-B189-EF93D8FC8B3B-1 | TCGA-THCA/TCGA-CE-A482-01Z-00-DX1.0F46244F-5C28-41EA-B189-EF93D8FC8B3B.pt | [
{
"from": "human",
"value": "<image>\nCan you provide an overall description of the whole slide image?"
},
{
"from": "gpt",
"value": "The slide presents a mixture of histological features, dominated by a patchy distribution of cells lacking significant streaming or storiform pattern. There is no... |
MorDetail_TCGA-DX-AB2V-01Z-00-DX4.F37742FF-5ACD-4A37-ACBE-8F11914DC5D8-2 | TCGA-SARC/TCGA-DX-AB2V-01Z-00-DX4.F37742FF-5ACD-4A37-ACBE-8F11914DC5D8.pt | [
{
"from": "human",
"value": "<image>\nDo the tumor cells display nuclear pleomorphism?"
},
{
"from": "gpt",
"value": "Yes, the tumor cells exhibit moderate nuclear pleomorphism with elongated nuclei. There is noticeable variability in both the size and shape of the nuclei, which are irregular an... |
Conversation_TCGA-AA-3662-01Z-00-DX1.625F1BCC-5E59-411E-AE23-6F43CE6122B2-1 | TCGA-COAD/TCGA-AA-3662-01Z-00-DX1.625F1BCC-5E59-411E-AE23-6F43CE6122B2.pt | [
{
"from": "human",
"value": "<image>\nCan you provide an overall description of the whole slide image?"
},
{
"from": "gpt",
"value": "The slide displays colonic tissue with moderately differentiated epithelial cells forming glandular structures that deviate somewhat from normal architecture. The... |
Morphology_choice_TCGA-EB-A4P0-01Z-00-DX1.9B525DEA-619A-43B6-B9C4-BB98511DEE56-1 | TCGA-SKCM/TCGA-EB-A4P0-01Z-00-DX1.9B525DEA-619A-43B6-B9C4-BB98511DEE56.pt | [
{
"from": "human",
"value": "<image>\nWhat pattern of tumor infiltration is noted in this poorly differentiated melanoma specimen? A) Tumor cells are limited to the epidermis with no deeper penetration. B) Tumor cells penetrate the reticular dermis with lymphatic invasion present. C) There is extensiv... |
Conversation_TCGA-4A-A93Y-01Z-00-DX1.AEA9169D-99CD-4107-B7FE-A58D6BD85758-1 | TCGA-KIRP/TCGA-4A-A93Y-01Z-00-DX1.AEA9169D-99CD-4107-B7FE-A58D6BD85758.pt | [
{
"from": "human",
"value": "<image>\nCan you provide an overall description of the whole slide image?"
},
{
"from": "gpt",
"value": "The slide displays papillary structures with fibrovascular cores lined by epithelial cells. These structures are typical of the tumor pattern observed here, with ... |
Subtype_TCGA-D8-A140-01Z-00-DX1.5B9382C0-332C-4FBF-82CD-B9453D02B815-1 | TCGA-BRCA/TCGA-D8-A140-01Z-00-DX1.5B9382C0-332C-4FBF-82CD-B9453D02B815.pt | [
{
"from": "human",
"value": "<image>\nBased on the immunohistochemical results showing 75% positive estrogen receptor (ER) status, 30% positive progesterone receptor (PR) status, and a HER2 score of 3+ with positive reaction, what is the molecular subtype of this breast cancer?"
},
{
"from": "gpt",
... |
MorDetail_TCGA-DG-A2KK-01Z-00-DX1.248D92C3-AD5B-4F3C-AE5C-6F8C70C7AE87-1 | TCGA-CESC/TCGA-DG-A2KK-01Z-00-DX1.248D92C3-AD5B-4F3C-AE5C-6F8C70C7AE87.pt | [
{
"from": "human",
"value": "<image>\nDo the epithelial cells display pleomorphism and anaplasia?"
},
{
"from": "gpt",
"value": "Yes, the epithelial cells show marked pleomorphism and anaplasia. The cells vary widely in size and shape, and they lack differentiation, indicating a high degree of a... |
MorDetail_TCGA-CV-7178-01Z-00-DX1.8938642C-55C3-4FAD-9106-0CA8B1040B9D-1 | TCGA-HNSC/TCGA-CV-7178-01Z-00-DX1.8938642C-55C3-4FAD-9106-0CA8B1040B9D.pt | [
{
"from": "human",
"value": "<image>\nIs there evidence of irregular nests and strands of atypical squamous cells infiltrating the mandible bone structure?"
},
{
"from": "gpt",
"value": "Yes, the slide shows irregular nests and strands of atypical squamous cells penetrating the adjacent mandible... |
Conversation_TCGA-VQ-AA6A-01Z-00-DX1.52D958F4-34B3-43F1-9DAC-960E69C958CA-1 | TCGA-STAD/TCGA-VQ-AA6A-01Z-00-DX1.52D958F4-34B3-43F1-9DAC-960E69C958CA.pt | [
{
"from": "human",
"value": "<image>\nCan you describe the overall findings observed in this whole slide image?"
},
{
"from": "gpt",
"value": "The whole slide image reveals a moderately differentiated adenocarcinoma exhibiting an intestinal type, based on the Lauren classification. There is a no... |
Prognosis_TCGA-D8-A1XS-01Z-00-DX1.E5C78E5A-947C-499D-9E95-619FEEC63E69-1 | TCGA-BRCA/TCGA-D8-A1XS-01Z-00-DX1.E5C78E5A-947C-499D-9E95-619FEEC63E69.pt | [
{
"from": "human",
"value": "<image>\nWith the diagnosis of moderately differentiated invasive ductal carcinoma with focal micropapillary features, TNM staging of T2N3A, and IHC results showing high positivity for estrogen and progesterone receptors as well as HER2 (3+), is the prognosis good or poor?"
},... |
MorDetail_TCGA-KO-8405-01Z-00-DX1.DB2F9FFE-B562-4D52-A4DF-E939DE99B5F7-3 | TCGA-KICH/TCGA-KO-8405-01Z-00-DX1.DB2F9FFE-B562-4D52-A4DF-E939DE99B5F7.pt | [
{
"from": "human",
"value": "<image>\nIs nuclear pleomorphism observed in the tumor cells?"
},
{
"from": "gpt",
"value": "Yes, there is notable nuclear pleomorphism among the tumor cells, with moderate irregularities in size and shape. The nuclei show significant atypia, being larger and more va... |
Report_TCGA-77-8154-01Z-00-DX1.5ca9afa5-e5d8-46d7-b542-c27649bd214e-1 | TCGA-LUSC/TCGA-77-8154-01Z-00-DX1.5ca9afa5-e5d8-46d7-b542-c27649bd214e.pt | [
{
"from": "human",
"value": "<image>\nWhat does the whole slide histopathology image depict, and what is the diagnosis?"
},
{
"from": "gpt",
"value": "Microscopic observation of the pathology slide reveals a moderately differentiated squamous cell carcinoma partially obliterating a bronchus, wit... |
Diagnosis_choice_TCGA-W5-AA30-01A-03-TS3.43CEE268-44B1-49C6-AA78-0EFC959FEE72-1 | TCGA-CHOL/TCGA-W5-AA30-01A-03-TS3.43CEE268-44B1-49C6-AA78-0EFC959FEE72.pt | [
{
"from": "human",
"value": "<image>\nBased on the observed features, what do you think is the correct histological classification of the tumor? A) Hepatocellular carcinoma B) Cholangiocarcinoma C) Metastatic colorectal carcinoma D) Hepatoblastoma"
},
{
"from": "gpt",
"value": "B"
}
] |
Conversation_TCGA-49-AARE-01Z-00-DX1.3559B3A9-6699-472F-B731-1BD9F93EE82A-3 | TCGA-LUAD/TCGA-49-AARE-01Z-00-DX1.3559B3A9-6699-472F-B731-1BD9F93EE82A.pt | [
{
"from": "human",
"value": "<image>\nWhat is the histological classification based on your examination of the slide?"
},
{
"from": "gpt",
"value": "The histological classification of the findings on this slide is poorly differentiated adenocarcinoma. This is characterized by the poorly differen... |
Morphology_choice_TCGA-A6-6650-01Z-00-DX1.92f39e59-8784-4dfd-a06f-804bebcdfb26-3 | TCGA-COAD/TCGA-A6-6650-01Z-00-DX1.92f39e59-8784-4dfd-a06f-804bebcdfb26.pt | [
{
"from": "human",
"value": "<image>\nWhat are the notable features of the cellular morphology in this slide? A) The nuclei are uniform in appearance, showing no signs of pleomorphism. B) Nuclei are highly variable with significant pleomorphism and numerous mitotic figures. C) There is moderate variability ... |
Diagnosis_choice_TCGA-CC-A3MA-01Z-00-DX1.96F9CA78-2690-4FAF-859A-D3D9CCBA98F1-1 | TCGA-LIHC/TCGA-CC-A3MA-01Z-00-DX1.96F9CA78-2690-4FAF-859A-D3D9CCBA98F1.pt | [
{
"from": "human",
"value": "<image>\nBased on the observed features, what do you think is the correct histological classification of the tumor? A) Hepatocellular carcinoma B) Cholangiocarcinoma C) Metastatic adenocarcinoma D) Angiosarcoma"
},
{
"from": "gpt",
"value": "A"
}
] |
Conversation_TCGA-EM-A4FN-01Z-00-DX1.9B07A541-3B90-4906-B168-B4B864C12FD5-1 | TCGA-THCA/TCGA-EM-A4FN-01Z-00-DX1.9B07A541-3B90-4906-B168-B4B864C12FD5.pt | [
{
"from": "human",
"value": "<image>\nCan you provide an overall description of the pathology slide?"
},
{
"from": "gpt",
"value": "The slide exhibits a multifocal pattern of papillary structures primarily lined by atypical epithelial cells, showcasing overlapping nuclei and nuclear grooves. The... |
Report_TCGA-OR-A5LT-01Z-00-DX1.030142AE-23DC-4082-87B4-D4D6E4CB9335-1 | TCGA-ACC/TCGA-OR-A5LT-01Z-00-DX1.030142AE-23DC-4082-87B4-D4D6E4CB9335.pt | [
{
"from": "human",
"value": "<image>\nProvide a concise report on the histopathological features and the diagnosis of the whole slide image."
},
{
"from": "gpt",
"value": "Microscopic observation of the pathology slide reveals cells with abundant eosinophilic (oxyphilic) cytoplasm invading the a... |
Conversation_TCGA-DJ-A1QD-01Z-00-DX1.69F164F2-DC35-473E-9DF6-142F83CD424F-1 | TCGA-THCA/TCGA-DJ-A1QD-01Z-00-DX1.69F164F2-DC35-473E-9DF6-142F83CD424F.pt | [
{
"from": "human",
"value": "<image>\nCan you provide an overall description of the whole slide image (WSI)?"
},
{
"from": "gpt",
"value": "The whole slide image prominently features papillary architecture characterized by complex branching fibrovascular cores. These are lined with epithelial ce... |
Diagnosis_choice_TCGA-IF-A4AK-01Z-00-DX1.A39253B8-4899-4360-BFF2-3538AEF7A970-2 | TCGA-SARC/TCGA-IF-A4AK-01Z-00-DX1.A39253B8-4899-4360-BFF2-3538AEF7A970.pt | [
{
"from": "human",
"value": "<image>\nWhat is the grading of this tumor according to its differentiation? A) Well differentiated B) Moderately differentiated C) Poorly differentiated D) Undifferentiated"
},
{
"from": "gpt",
"value": "C"
}
] |
Conversation_TCGA-UY-A9PB-01Z-00-DX1.4ACBFEEA-703A-47AF-A67D-359B9F027DD0-2 | TCGA-BLCA/TCGA-UY-A9PB-01Z-00-DX1.4ACBFEEA-703A-47AF-A67D-359B9F027DD0.pt | [
{
"from": "human",
"value": "<image>\nWhich observed features are most significant for making a diagnosis?"
},
{
"from": "gpt",
"value": "The most significant features include the marked nuclear enlargement and pleomorphism of atypical urothelial cells, the extensive infiltration into the muscul... |
Diagnosis_choice_TCGA-77-7139-01Z-00-DX1.b8b79b0c-4ea0-4f6c-8e6e-29ad76eca78f-1 | TCGA-LUSC/TCGA-77-7139-01Z-00-DX1.b8b79b0c-4ea0-4f6c-8e6e-29ad76eca78f.pt | [
{
"from": "human",
"value": "<image>\nBased on the observed features, what do you think is the correct histological classification of the tumor? A) Well-differentiated squamous cell carcinoma B) Adenocarcinoma C) Poorly differentiated squamous cell carcinoma D) Small cell carcinoma"
},
{
"from": "gp... |
Report_TCGA-BH-A0DV-01Z-00-DX1.2F0B5FB3-40F0-4D27-BFAC-390FB9A42B39-1 | TCGA-BRCA/TCGA-BH-A0DV-01Z-00-DX1.2F0B5FB3-40F0-4D27-BFAC-390FB9A42B39.pt | [
{
"from": "human",
"value": "<image>\nProvide a concise report on the histopathological features and the diagnosis of the whole slide image."
},
{
"from": "gpt",
"value": "Microscopic observation of the pathology slide reveals irregular clusters of epithelial cells infiltrating the stroma, formi... |
Conversation_TCGA-3U-A98G-01Z-00-DX1.5315FC96-F850-44EA-8480-04EDD64B1BAF-1 | TCGA-MESO/TCGA-3U-A98G-01Z-00-DX1.5315FC96-F850-44EA-8480-04EDD64B1BAF.pt | [
{
"from": "human",
"value": "<image>\nCan you provide an overall description of the whole slide image (WSI)?"
},
{
"from": "gpt",
"value": "The slide presents a biphasic pattern of mesothelioma, with a predominant epithelioid component making up 80% of the tumor. This component is characterized ... |
Diagnosis_choice_TCGA-AR-A0TQ-01Z-00-DX1.2BEA298C-6B3D-4133-ADBC-769E62CEFFA0-1 | TCGA-BRCA/TCGA-AR-A0TQ-01Z-00-DX1.2BEA298C-6B3D-4133-ADBC-769E62CEFFA0.pt | [
{
"from": "human",
"value": "<image>\nBased on the observed features, what do you think is the correct histological classification of the tumor? A) Infiltrating lobular carcinoma B) Medullary carcinoma C) Ductal carcinoma in situ D) Infiltrating ductal carcinoma"
},
{
"from": "gpt",
"value": "D"... |
Conversation_TCGA-56-7579-01Z-00-DX1.627f65b9-ac66-4f71-a6f4-394338b647f0-2 | TCGA-LUSC/TCGA-56-7579-01Z-00-DX1.627f65b9-ac66-4f71-a6f4-394338b647f0.pt | [
{
"from": "human",
"value": "<image>\nWhich observed features are most significant for making a diagnosis?"
},
{
"from": "gpt",
"value": "The significant features include nests and cords of squamous cells with intercellular bridges, keratinization, and moderate nuclear pleomorphism. Keratinizati... |
MorDetail_TCGA-BH-A1EX-01Z-00-DX1.16B6A817-6729-446E-9FCF-A4A333C5295D-1 | TCGA-BRCA/TCGA-BH-A1EX-01Z-00-DX1.16B6A817-6729-446E-9FCF-A4A333C5295D.pt | [
{
"from": "human",
"value": "<image>\nDo the epithelial cells infiltrate the surrounding stromal tissue?"
},
{
"from": "gpt",
"value": "Yes, the epithelial cells are infiltrating the surrounding stromal tissue, indicating invasive behavior. They extend beyond their usual boundaries into the stro... |
Morphology_TCGA-A3-3357-01Z-00-DX1.b85a8293-7b4f-4a8a-b799-77d7d7b39b3e-2 | TCGA-KIRC/TCGA-A3-3357-01Z-00-DX1.b85a8293-7b4f-4a8a-b799-77d7d7b39b3e.pt | [
{
"from": "human",
"value": "<image>\nWhat observations can you make about the tissue architecture on this slide?"
},
{
"from": "gpt",
"value": "The tumor shows irregular nests of clear cells surrounded by a stroma with a delicate vasculature. The architecture is notable for the absence of any c... |
Morphology_choice_TCGA-DK-A3WW-01Z-00-DX1.4C3751B5-BD3E-4902-A092-B5877B67851F-2 | TCGA-BLCA/TCGA-DK-A3WW-01Z-00-DX1.4C3751B5-BD3E-4902-A092-B5877B67851F.pt | [
{
"from": "human",
"value": "<image>\nHow does the tissue architecture of the tumor deviate from normal epithelial structures? A) The tumor shows glandular structures with moderate deviation from normal tissue architecture. B) The tumor forms highly organized acinar structures, similar to normal glands. C) ... |
Conversation_TCGA-D3-A2J6-06Z-00-DX1.1E4860D2-EC44-47BA-88AD-CE524E3CC2B7-3 | TCGA-SKCM/TCGA-D3-A2J6-06Z-00-DX1.1E4860D2-EC44-47BA-88AD-CE524E3CC2B7.pt | [
{
"from": "human",
"value": "<image>\nWhat is the histological classification based on your examination of the slide?"
},
{
"from": "gpt",
"value": "The histological examination indicates malignant melanoma. This classification is supported by the metastatic nature of the cells infiltrating the ... |
MorDetail_TCGA-BT-A20R-01Z-00-DX1.38320FC0-F1E5-401B-9336-D77796456B30-6 | TCGA-BLCA/TCGA-BT-A20R-01Z-00-DX1.38320FC0-F1E5-401B-9336-D77796456B30.pt | [
{
"from": "human",
"value": "<image>\nWhat is the appearance of the benign leiomyoma found in the perivesical adipose tissue?"
},
{
"from": "gpt",
"value": "The benign leiomyoma within the perivesical adipose tissue appears as a well-circumscribed nodule composed of spindle-shaped smooth muscle ... |
Conversation_TCGA-N7-A4Y8-01Z-00-DX4.94589553-78C5-414A-92C9-78EAE3375F37-2 | TCGA-UCS/TCGA-N7-A4Y8-01Z-00-DX4.94589553-78C5-414A-92C9-78EAE3375F37.pt | [
{
"from": "human",
"value": "<image>\nWhich observed features are most important for making a diagnosis?"
},
{
"from": "gpt",
"value": "The critical features for diagnosis include the biphasic composition of the tumor, with both sarcomatous and carcinomatous elements. The high-grade sarcomatous ... |
Diagnosis_choice_TCGA-CF-A3MI-01Z-00-DX1.5619CA1A-F772-44CC-BBE2-F2C365E2699D-2 | TCGA-BLCA/TCGA-CF-A3MI-01Z-00-DX1.5619CA1A-F772-44CC-BBE2-F2C365E2699D.pt | [
{
"from": "human",
"value": "<image>\nWhat is the grading of this tumor according to its differentiation? A) Well differentiated B) Moderately differentiated C) Poorly differentiated D) Undifferentiated"
},
{
"from": "gpt",
"value": "C"
}
] |
MorDetail_TCGA-A2-A04Y-01Z-00-DX1.4DC97AD6-4806-4A3A-A998-FD36F93590A4-4 | TCGA-BRCA/TCGA-A2-A04Y-01Z-00-DX1.4DC97AD6-4806-4A3A-A998-FD36F93590A4.pt | [
{
"from": "human",
"value": "<image>\nAre there any signs of tumor necrosis?"
},
{
"from": "gpt",
"value": "No, there are no signs of tumor necrosis observed in the examined sample. The tissue does not exhibit areas of cell death, which is often characterized by loss of the normal tissue structu... |
Morphology_choice_TCGA-XU-A931-01Z-00-DX1.4AE0C30A-F31A-4A1B-B539-750DB8DD4994-2 | TCGA-THYM/TCGA-XU-A931-01Z-00-DX1.4AE0C30A-F31A-4A1B-B539-750DB8DD4994.pt | [
{
"from": "human",
"value": "<image>\nHow is the tissue architecture described in this thymoma specimen? A) The tumor is composed entirely of solid sheets of cells with no distinct structures. B) The tumor shows nests of polygonal epithelial cells separated by thick fibrous septae. C) The tumor demonstrates... |
Conversation_TCGA-A3-3365-01Z-00-DX1.dc5b8d77-b5ba-47c8-b536-a8f1ed458ed3-1 | TCGA-KIRC/TCGA-A3-3365-01Z-00-DX1.dc5b8d77-b5ba-47c8-b536-a8f1ed458ed3.pt | [
{
"from": "human",
"value": "<image>\nCan you describe the overall findings observed in this pathology slide?"
},
{
"from": "gpt",
"value": "The slide reveals a nodular lesion composed of clear cells with a granular cytoplasm, which is characteristic of renal carcinoma. The lesion is well-define... |
MorDetail_TCGA-CF-A47S-01Z-00-DX1.1397F7C0-1098-4C42-B158-28A37723F5F6-3 | TCGA-BLCA/TCGA-CF-A47S-01Z-00-DX1.1397F7C0-1098-4C42-B158-28A37723F5F6.pt | [
{
"from": "human",
"value": "<image>\nIs necrosis present in the tissue sample?"
},
{
"from": "gpt",
"value": "Yes, necrosis is present within the tissue. There are areas where tissue breakdown and cell death are evident, characterized by the loss of normal cellular structure and presence of cel... |
MorDetail_TCGA-DX-A8BJ-01Z-00-DX2.2E7D8A52-B4C6-45E9-82C8-3C5E5748046C-4 | TCGA-SARC/TCGA-DX-A8BJ-01Z-00-DX2.2E7D8A52-B4C6-45E9-82C8-3C5E5748046C.pt | [
{
"from": "human",
"value": "<image>\nHow does the tumor interact with skeletal muscle fibers and fibro-adipose tissue?"
},
{
"from": "gpt",
"value": "The tumor shows involvement with skeletal muscle fibers and fibro-adipose tissue. The tumor cells infiltrate and disrupt these structures, causin... |
MorDetail_TCGA-FE-A237-01Z-00-DX1.4D6E9100-0586-43A9-9070-B24F1BD1E7A9-4 | TCGA-THCA/TCGA-FE-A237-01Z-00-DX1.4D6E9100-0586-43A9-9070-B24F1BD1E7A9.pt | [
{
"from": "human",
"value": "<image>\nAre psammoma bodies present in the tissue?"
},
{
"from": "gpt",
"value": "Yes, abundant psammoma bodies are noted within the nodule. Psammoma bodies are round, concentrically laminated calcific deposits commonly associated with papillary carcinoma. Their pre... |
Morphology_TCGA-XF-AAMR-01Z-00-DX1.7BFF4F04-9B60-41AA-9977-AF63547748AB-2 | TCGA-BLCA/TCGA-XF-AAMR-01Z-00-DX1.7BFF4F04-9B60-41AA-9977-AF63547748AB.pt | [
{
"from": "human",
"value": "<image>\nWhat observations can you make about the tissue architecture on this slide?"
},
{
"from": "gpt",
"value": "The tissue architecture is significantly distorted, primarily due to the invasive nature of the carcinoma. The structural arrangement of the bladder wa... |
Diagnosis_choice_TCGA-HQ-A5NE-01Z-00-DX1.8046B606-085B-406F-A8D7-92A3E021020A-1 | TCGA-BLCA/TCGA-HQ-A5NE-01Z-00-DX1.8046B606-085B-406F-A8D7-92A3E021020A.pt | [
{
"from": "human",
"value": "<image>\nBased on the observed features, what do you think is the correct histological classification of the tumor? A) Squamous cell carcinoma B) Invasive adenocarcinoma C) Invasive transitional cell (urothelial) carcinoma D) Papillary carcinoma"
},
{
"from": "gpt",
... |
Morphology_TCGA-HT-7480-01Z-00-DX1.42E0C267-020A-464E-9652-2068BEC181B8-1 | TCGA-LGG/TCGA-HT-7480-01Z-00-DX1.42E0C267-020A-464E-9652-2068BEC181B8.pt | [
{
"from": "human",
"value": "<image>\nCan you describe the pattern of tumor infiltration?"
},
{
"from": "gpt",
"value": "The tumor demonstrates diffuse infiltration into both white and gray matter, characterized by a widespread dispersion of neoplastic cells that intermingle with normal brain ti... |
Morphology_choice_TCGA-XV-A9W5-01Z-00-DX1.5FE52223-15BC-4DA0-A901-F7E4730AB6E7-1 | TCGA-SKCM/TCGA-XV-A9W5-01Z-00-DX1.5FE52223-15BC-4DA0-A901-F7E4730AB6E7.pt | [
{
"from": "human",
"value": "<image>\nWhat is the observed pattern of tumor infiltration in this melanoma specimen? A) Tumor cells remain confined to the epidermis with no dermal invasion. B) Tumor cells penetrate into deeper skin layers without vascular invasion. C) Tumor cells infiltrate vascular structur... |
Morphology_TCGA-QS-A5YQ-01Z-00-DX1.DDF17CB8-4995-4A4D-AFA7-E84BEEA84E3F-2 | TCGA-UCEC/TCGA-QS-A5YQ-01Z-00-DX1.DDF17CB8-4995-4A4D-AFA7-E84BEEA84E3F.pt | [
{
"from": "human",
"value": "<image>\nWhat observations can you make about the tissue architecture on this slide?"
},
{
"from": "gpt",
"value": "The tissue architecture consists of complex glandular structures that significantly deviate from the normal arrangement. The glands are closely packed ... |
Morphology_choice_TCGA-DX-A48P-01Z-00-DX1.682228F3-45D8-4482-86B1-B4E616BBF40A-1 | TCGA-SARC/TCGA-DX-A48P-01Z-00-DX1.682228F3-45D8-4482-86B1-B4E616BBF40A.pt | [
{
"from": "human",
"value": "<image>\nWhat observations can you make about the tissue architecture on this slide displaying leiomyosarcoma, NOS? A) The tumor shows irregular glandular structures with abnormal tissue architecture. B) The tumor is organized in round to oval nodular fragments with notable smoo... |
Stage_choice_TCGA-AG-3887-01Z-00-DX1.4973b987-ee11-4a5b-a2ba-d9910b363486-1 | TCGA-READ/TCGA-AG-3887-01Z-00-DX1.4973b987-ee11-4a5b-a2ba-d9910b363486.pt | [
{
"from": "human",
"value": "<image>\nWhat is the TNM staging for a patient with a tumor size of over 5 cm, no regional lymph node involvement, and no distant metastasis? A) T2 N0 M0 B) T1 N0 M0 C) T3 N0 M0 D) T4 N1 M0"
},
{
"from": "gpt",
"value": "C"
}
] |
Morphology_TCGA-CJ-6031-01Z-00-DX1.372B4225-F672-4E8F-9873-3A4FE6A7982A-2 | TCGA-KIRC/TCGA-CJ-6031-01Z-00-DX1.372B4225-F672-4E8F-9873-3A4FE6A7982A.pt | [
{
"from": "human",
"value": "<image>\nWhat observations can you make about the tissue architecture on this slide?"
},
{
"from": "gpt",
"value": "The tissue architecture demonstrates a predominant proliferation of clear cells, which are organized in nests and sheets. Central areas exhibit marked ... |
Morphology_choice_TCGA-DX-A8BL-01Z-00-DX3.3049E293-9505-4B7E-B470-A1B80CACC0F6-3 | TCGA-SARC/TCGA-DX-A8BL-01Z-00-DX3.3049E293-9505-4B7E-B470-A1B80CACC0F6.pt | [
{
"from": "human",
"value": "<image>\nWhat are the notable features of the cellular morphology in this slide? A) Nuclei are uniform in appearance, showing no signs of active division. B) There is minimal variability in nuclear size, with a low rate of cell division. C) Nuclei are considerably pleomorphic wi... |
Report_TCGA-FG-A713-01Z-00-DX3.61A211D7-4E07-48F3-BCA4-B05B0EDE5AB3-1 | TCGA-LGG/TCGA-FG-A713-01Z-00-DX3.61A211D7-4E07-48F3-BCA4-B05B0EDE5AB3.pt | [
{
"from": "human",
"value": "<image>\nHow would you summarize the morphological features and diagnosis in the whole slide histopathology image?"
},
{
"from": "gpt",
"value": "Microscopic observation of the pathology slide reveals evidence of infiltrating glioma, characterized by areas of hyperce... |
Morphology_choice_TCGA-HT-7472-01Z-00-DX1.79C3FA08-7FCF-46EE-972D-B8E06586619E-3 | TCGA-LGG/TCGA-HT-7472-01Z-00-DX1.79C3FA08-7FCF-46EE-972D-B8E06586619E.pt | [
{
"from": "human",
"value": "<image>\nWhat is observed in terms of cellular morphology in this glioma specimen? A) Cells exhibit highly irregular nuclei with abundant cytoplasm. B) Cells are hyperchromatic with prominent nucleoli and significant pleomorphism. C) Cells predominantly have round to somewhat ir... |
Diagnosis_choice_TCGA-ET-A25J-01Z-00-DX1.93E413F5-DDAE-4C04-B3C0-699A189893CC-1 | TCGA-THCA/TCGA-ET-A25J-01Z-00-DX1.93E413F5-DDAE-4C04-B3C0-699A189893CC.pt | [
{
"from": "human",
"value": "<image>\nBased on the observed features, what do you think is the correct histological classification of the tumor? A) Follicular carcinoma B) Medullary carcinoma C) Papillary carcinoma D) Anaplastic carcinoma"
},
{
"from": "gpt",
"value": "C"
}
] |
MorDetail_TCGA-21-5784-01Z-00-DX1.E50E7F4B-BE37-4171-94A7-E824CFF4B3BB-7 | TCGA-LUSC/TCGA-21-5784-01Z-00-DX1.E50E7F4B-BE37-4171-94A7-E824CFF4B3BB.pt | [
{
"from": "human",
"value": "<image>\nIs there any evidence of tumor involvement in the peribronchial lymph nodes?"
},
{
"from": "gpt",
"value": "There is no evidence of tumor involvement in the peribronchial lymph nodes seen on the slide. The lymph nodes appear unaffected by the carcinoma."
}... |
Morphology_TCGA-60-2695-01Z-00-DX1.4cc6c566-d60d-4ff9-9ea8-18a9da46ae6b-2 | TCGA-LUSC/TCGA-60-2695-01Z-00-DX1.4cc6c566-d60d-4ff9-9ea8-18a9da46ae6b.pt | [
{
"from": "human",
"value": "<image>\nWhat observations can you make about the tissue architecture on this slide?"
},
{
"from": "gpt",
"value": "The tissue architecture demonstrates poorly differentiated squamous epithelial cells with a basaloid appearance. These cells are organized in irregular... |
Morphology_choice_TCGA-D6-6515-01Z-00-DX2.270E24EB-B75B-4DA4-AD7D-217DBC83A3D7-2 | TCGA-HNSC/TCGA-D6-6515-01Z-00-DX2.270E24EB-B75B-4DA4-AD7D-217DBC83A3D7.pt | [
{
"from": "human",
"value": "<image>\nWhat observations can you make about the tissue architecture on this slide? A) The tumor shows glandular structures with moderate deviation from normal tissue architecture. B) The tumor forms highly organized squamous pearls. C) The tumor is composed entirely of solid s... |
Report_TCGA-AD-6890-01Z-00-DX1.4778042f-f210-489c-bb76-b4fe16b0d500-1 | TCGA-COAD/TCGA-AD-6890-01Z-00-DX1.4778042f-f210-489c-bb76-b4fe16b0d500.pt | [
{
"from": "human",
"value": "<image>\nHow would you summarize the morphological features and diagnosis in the whole slide histopathology image?"
},
{
"from": "gpt",
"value": "Microscopic observation of the pathology slide reveals moderately differentiated adenocarcinoma with tumor cells forming ... |
Morphology_TCGA-SP-A6QI-01Z-00-DX1.12CA08CC-2F40-4B0E-AEC3-8A1FCFA362F8-1 | TCGA-PCPG/TCGA-SP-A6QI-01Z-00-DX1.12CA08CC-2F40-4B0E-AEC3-8A1FCFA362F8.pt | [
{
"from": "human",
"value": "<image>\nWhat observations can you make about the tissue architecture on this slide?"
},
{
"from": "gpt",
"value": "The tumor exhibits a solid nesting and trabecular architecture, characterized by tightly packed nests of cells and trabecular formations interwoven wit... |
Morphology_choice_TCGA-G3-A5SJ-01Z-00-DX1.9218552C-F326-4B10-BCBA-031B32E8F905-3 | TCGA-LIHC/TCGA-G3-A5SJ-01Z-00-DX1.9218552C-F326-4B10-BCBA-031B32E8F905.pt | [
{
"from": "human",
"value": "<image>\nWhat are the notable features of the cellular morphology in this slide of hepatocellular carcinoma? A) Cells exhibit uniform size and shape with low mitotic activity. B) The nuclei display significant pleomorphism with numerous mitoses and high cellular atypia. C) Nucle... |
Diagnosis_choice_TCGA-A8-A06Q-01Z-00-DX1.622AC6E4-DB1A-4C8D-8185-52D4FD1F30B4-2 | TCGA-BRCA/TCGA-A8-A06Q-01Z-00-DX1.622AC6E4-DB1A-4C8D-8185-52D4FD1F30B4.pt | [
{
"from": "human",
"value": "<image>\nWhat is the grading of this tumor according to the Nottingham system given the observed features? A) NHG1 B) NHG2 C) NHG3 D) Not applicable"
},
{
"from": "gpt",
"value": "B"
}
] |
MorDetail_TCGA-A5-A7WK-01Z-00-DX1.A3C77356-8EEE-4901-A4A0-72FD934947C0-6 | TCGA-UCEC/TCGA-A5-A7WK-01Z-00-DX1.A3C77356-8EEE-4901-A4A0-72FD934947C0.pt | [
{
"from": "human",
"value": "<image>\nIs adenomyosis present in the observed tissue?"
},
{
"from": "gpt",
"value": "Yes, multifocal adenomyosis is observed, characterized by the presence of endometrial glands and stroma extending into the myometrium. The surrounding endometrial tissue appears in... |
Diagnosis_choice_TCGA-QK-A652-01Z-00-DX1.CCE949FD-A9F4-4EE2-8A5E-C1AED3852274-1 | TCGA-HNSC/TCGA-QK-A652-01Z-00-DX1.CCE949FD-A9F4-4EE2-8A5E-C1AED3852274.pt | [
{
"from": "human",
"value": "<image>\nBased on the observed features, what do you think is the correct histological classification of the tumor? A) Basal cell carcinoma B) Ductal carcinoma in situ C) Keratinizing squamous cell carcinoma D) Invasive lobular carcinoma"
},
{
"from": "gpt",
"val... |
MorDetail_TCGA-2H-A9GO-01Z-00-DX1.A3AEE5BB-3825-49B4-8F7B-B2CB9015515A-4 | TCGA-ESCA/TCGA-2H-A9GO-01Z-00-DX1.A3AEE5BB-3825-49B4-8F7B-B2CB9015515A.pt | [
{
"from": "human",
"value": "<image>\nIs vascular invasion observed in this slide?"
},
{
"from": "gpt",
"value": "No, vascular invasion is not observed. The malignant cells are not found within the lumens of blood vessels or lymphatic channels in this slide, indicating no evidence of vascular in... |
Morphology_choice_TCGA-RW-A7D0-01Z-00-DX1.DA17341B-E641-4FEC-9126-055334DCA57A-1 | TCGA-PCPG/TCGA-RW-A7D0-01Z-00-DX1.DA17341B-E641-4FEC-9126-055334DCA57A.pt | [
{
"from": "human",
"value": "<image>\nCan you describe the pattern of tumor infiltration in this adrenal gland mass? A) Tumor cells infiltrate the stroma, but without any vascular or neural involvement. B) Tumor mass remains well-encapsulated with no evidence of vascular invasion. C) Tumor cells show extens... |
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