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[Phospholipid characteristics of the HDLP2 and HDLP3 composition in dysalphalipoproteinemia].
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10,000,001
There has been determined the phospholipid composition in HDLP2 and HDLP3 obtained from the blood plasma of males with different cholesterol (CS) level of HDLP. An increase in CS of HDLP is shown to be associated with the increase in a percentage of phosphatidylcholine, a proportion of phosphatidylcholine/sphingomyelin and a reduction of the percentage of sphingomyelin (mainly in HDLP2) and to a lesser extent--in HDLP3. A direct correlation has been established between the level of CS of HDLP obtained from the blood plasma of males living in 3 different geographical zones of the USSR and the indices of the phospholipid composition of HDLP2. Changes found in the phospholipid composition of HDLP3 in dysalphalipoproteidemia are associated with a difference in the triglyceride level of the blood plasma.
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10,000,002
Preparation and properties of chromium(III) adenosine 5'-triphosphate, chromium(III) adenosine 5'-diphosphate, and related chromium(III) complexes.
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10,000,003
Effect of sodium copper chlorophyllin on the formation of calcium oxalate crystals in rat kidney.
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10,000,004
We induced the deposition of calcium oxalate crystals in rat kidney by intraperitoneal administration of 4-hydroxy-L-proline or sodium oxalate and studied the amounts and size distribution characteristics of the deposited crystals. Intravenous administration of sodium copper chlorophyllin inhibited the deposition and growth of calcium oxalate crystals induced by 4-hydroxy-L-proline or sodium oxalate. This finding may be of importance in calcium oxalate urolithiasis.
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10,000,005
Structure of an amniotic fluid component, 7-(4,5-cis-dihydroxy-1-cyclopenten-3-ylaminomethyl)-7-deazaguanine (queuine), a substrate for tRNA: guanine transglycosylase.
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10,000,006
A compound present in bovine amniotic fluid, and which is a substrate for tRNA:guanine transglycosylase, has been structurally characterized as queuine, a hypermodified base which occurs in transfer RNA. The structure assignment is based on mass spectrometry, proton nuclear magnetic resonance, and ultraviolet absorbance data.
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10,000,007
Folic acid binding protein in subjects with low serum folate.
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10,000,008
The staphylococcal phosphoenolpyruvate-dependent phosphotransferase system. Purification and characterisation of the galactoside-specific membrane-component enzyme II.
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10,000,009
The galactoside-specific membrane-bound component of the staphylococcal phosphoenolpyruvate-dependent phosphotransferase system, enzyme IIlac, was purified to homogeneity. The purification procedure involved several extractions steps at the particulate state, followed by solubilisation with Triton X-100. Up to this stage the biological activity of enzyme II was preserved. Isolation of the homogeneous protein involved gel filtration of the dodecylsulfate-denatured material. An apparent molecular weight of the polypeptide chain was estimated by dodecylsulfate gel electrophoresis. The 55000-Mr protein is visible in dodecylsulfate gels upon induction of the staphylococcal lac operon as a more intensively stained area. Antibodies against the denatured 55000-Mr protein inhibit the mutant complementation assay of enzyme II offered as membrane fragments. This demonstrates that the 55000-Mr protein and enzyme IIlac are identical. Polarity and the solubility of the protein in detergents are typical for an integral membrane protein.
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10,000,010
Evidence that the low-affinity folate-binding protein in erythrocyte hemolysate is identical to hemoglobin.
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10,000,011
Gel filtration studies on erythrocyte hemolysate demonstrated the presence of a folate binding protein, apparently of the low-affinity type, that co-elutes with hemoglobin. Further, the folate binder eluted with a low salt concentration after DEAE-Sepharose CL-6B anion-exchange chromatography of erythrocyte hemolysate at pH 6.3. The chromatographic behavior of hemoglobin labeled with [3H]folate was so similar to that of the present binder as to suggest that the folate binder in erythrocytes is in fact hemoglobin.
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10,000,012
Discrete Distribution of binding sites for Dolichos biflorus agglutinin (DBA) and for peanut agglutinin (PNA) in mouse organ tissues.
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10,000,013
The distribution of binding sites for two lectins with different specificities was studied in adult mice by staining paraffin sections with lectins labeled either with fluorescein isothiocyanate or horseradish peroxidase. Binding sites for Dolichos biflorus agglutinin, a lectin specific to terminal alpha-N-acetylgalactosamine residue, were detected only in several restricted regions, such as collecting tubules and Bowman's capsules of the kidney, bile ducts, pancreatic ducts, sperms, oocytes, some secreting cells, and the secreted mucin itself. Binding sites for peanut agglutinin (PNA), a lectin specific to terminal beta-galactosyl residue, were distributed more widely. However, differentiation-dependent alterations in the expression of PNA binding sites have been observed in two types of cell lineage. During the course of spermatogenesis, the binding sites were expressed at the stage of spermatocytes. In the epithelium of esophagus, the binding sites were present in cells of the superficial layer.
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10,000,014
Baumycin analogs isolated from Actinomadura sp.
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-0.0024633111897855997, 0.0008111656061373651 ]
10,000,015
Stimulation of the release of two glycoproteins from mouse 3T3 cells by growth factors and by agents that increase intralysosomal pH.
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10,000,016
LY79771: a novel compound for weight control.
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10,000,017
[Proximal gastric vagotomy - operative technic].
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10,000,018
The insertion of pig microvillus aminopeptidase into the membrane as probed by [125I]iodonaphthylazide.
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10,000,019
The insertion of pig intestinal microvillus aminopeptidase (EC 3.4.11.2) into the membrane was studied by the hydrophobic photolabel [125I]iodonaphthylazide. The aminopeptidase was either labelled in the microvillus membrane and purified, or labelled after detergent solubilization and purification in a buffer containing Triton X-100, and then isolated from the reaction mixture. Of the three subunits A (Mr 162000), B (Mr 123000) and C (Mr 62000) of the aminopeptidase, A and B, but not C contained radioactivity, indicating that both subunit A and B carry anchoring peptide. The radioactivity when released from the subunits by trypsin treatment was connected to low-molecular-weight material.
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10,000,020
[Surgical treatment of arterial insufficiency of the upper limbs].
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10,000,021
Cytogenetic effects of Rhodesian chrysotile on human lymphocytes in vitro.
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10,000,022
Cytogenetic studies were carried out on human lymphocytes from nine subjects; cells were incubated with Rhodesian chrysotile fibres (10 micrograms/ml) for 48 and 72 hours. After treatment, chromosome alterations were twice as frequent, and chromosome breaks showed the highest percentage increment. We focussed our attention on chromosome breaks, since they are typically induced by ionizing radiation and by chemical carcinogens, and in particular alkylating agents. Since asbestos strongly adsorbs proteins and since indications exist that the interaction may be selective, we consider that this type of interaction may be the cause of cytogenetic damage induced in vitro by asbestos.
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10,000,023
The rehabilitation counselor in private practice: perspectives for education and preparation.
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10,000,024
Chemical and nutritional studies on roselle seeds (Hibiscus sabdariffa L.).
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10,000,025
Unextracted and extracted roselle seeds (Hibiscus sabdariffa L.) were analysed for determining moisture, crude protein, ether extract, nitrogen-free extract, crude fiber, ash, calcium, phosphorus and sulfur. Digestibility trials with cocks showed that the digestible crude protein, total digestible nutrients, starch value and calculated metabolizable energy for the unextracted roselle seeds were 15.36%, 75.81%, 84.06% and 3184 kcal/kg respectively, the corresponding values for the extracted seeds were 27.50%, 68.83%, 64.23% and 2891 kcal/kg. Iodine number, saponification number, Reichert-Meissel and Polenske values for the roselle seed oil were 15.63, 258, 1.75 and 1.14 respectively.
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10,000,026
[Vitamin status in diabetic neuropathy (thiamine, riboflavin, pyridoxin, cobalamin and tocopherol)].
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10,000,027
Investigations on the vitamin pattern of diabetic neuropathy: thiamine, riboflavin, pyridoxine, cobalamin and tocopherol. The contents of the vitamins mentioned above have been measured in the blood of 119 patients (53 diabetic neuropathies, 66 diabetics without neuropathy). The incidence of neuropathy shows a strong correlation with the duration of the diabetic state, but not with sex, nor with concomitant diseases such as adipositas, hypertension, heart and circulatory diseases, except retinopathia diabetica. Most of the diabetics in our study are well supplied with vitamins B1, B2, and E; B6 and B12 are occasionally low, but there is no statistically relevant difference between diabetic controls and neuropathies. Adipose patients have neither a markedly different vitamin content nor a different calory uptake from non-adipose patients. A general trend towards reduced total calory uptake is seen in old age, men (lower protein intake) and women (lower carbohydrate intake) obviously differing somewhat in their habits. The influence of therapy on the vitamin pattern is not clear cut, except for patients under diet and biguanide-therapy showing a higher proportion of low or subnormal B12 values. The increased frequency of neuropathies in patients treated with sulfonyl-urea approaches only the limits of significance and needs further investigations.
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10,000,028
[Laterality and mother-child relations (author's transl)].
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10,000,029
Expanded programme on immunization in India: progress report.
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10,000,030
Study of physical growth and sexual maturation in a high socio-economic group from Bombay.
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10,000,031
[Tibial insertion tendinoses, achillodynia, and damage due to overuse of the foot-etiology, biomechanics, therapy (author's transl)].
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10,000,032
Group treatment of sexual dysfunction in gay men.
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10,000,033
Three different formats for treating gay men with sexual dysfunctions are described, with emphasis on group therapy for men who are without partners. Clients present with general sexual anxieties, lack of sexual desire, secondary erectile dysfunctions, and difficulties with ejaculatory control, both rapid and inhibited. The process of selecting a program, and in particular the factors to consider when deciding if a client should work with a lover, with a partner surrogate or in a group format, are discussed. Primary procedures of sex therapy in each of these formats are described. Some trends in the frequencies of presenting complaints are noted, as well as possible reasons for reported differences between homosexual and heterosexual men. Other special considerations for working with gay men in sex therapy are discussed. Results of a self-report survey of change, administered 6 weeks and again 6 months following the end of 5 different 10-week sex therapy groups, are reported.
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10,000,034
[Cryofibrinogen].
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10,000,035
[Biochemical basis of protein synthesis].
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10,000,036
[The preoperative medical evaluation of the aged woman].
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10,000,037
[Vascular pathology of femoral head necrosis (author's transl)].
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10,000,038
[Ergonovine effects upon hypophyseal circulation (author's transl)].
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10,000,039
[Various technics of local flapping].
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10,000,040
[Spondylitis tuberculosa (author's transl)].
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10,000,041
The use of radiographic studies in a teaching hospital.
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10,000,042
A study was conducted on the use of radiographic studies by 138 medical residents. They ordered an initial chest film on 88% of their patients and averaged a 34% yield. Though the range of other radiographic studies ordered per patient varied by a factor of 15, more than half the resident physicians ordered an average of less than one for every two patients. These physicians experienced overall yields between 0 and 100%, with half the residents averaging between 33 and 57%. This data base was then used to derive empirical norms of radiographic study utilization that can be employed to evaluate physicians' utilization in providing care to comparable populations.
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10,000,043
[Clinical observation of treatment of 281 cases of leptospirosis with methimidol hydrochloride (author's transl)].
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10,000,044
Psychiatric symptoms and symptom change during psychiatric hospitalization.
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10,000,045
[Oviductal physiological alterations and endosalpingiosis (author's transl)].
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10,000,046
A study was made of the oviducts from 110 patients salpingectomized between 1943 and 1976, after endosalpingiosis had been diagnosed. All of the patients were infertile women in whom histopathology performed after surgery revealed diverticula located mainly in the isthmic and interstitial portions of the oviductal wall. By either continuity or invasion, these configurations spread the endosalpingeal epithelium into the peritoneum and/or the ovary. Endosalpingiosis affects the muscular layer of the oviduct, which becomes thickened and rigid, thus accounting for the severe alterations of tubal physiology. The clinical aspects and microscopy of endosalpingiosis are described, and their differences from those of adnexo-peritoneal endometriosis are discussed.
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10,000,047
[Tachyphylaxis in continuous epidural anaesthesia with bupivacaine 0.125% and 0.25% (author's transl)].
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10,000,048
Based on the results in 105 patients under continual thoracic epidural analgesia differences in the dose response relationship of bolusinjections are found. While under bupivacaine 0.25% a decrease of the effectivity of additional bolusinjections can be stated, the dose response relationship does not change under bupivacaine 0.125%. Moreover the effectivity of bupivacaine 0.25% increases after an interruption of the local anaesthetic infusion. The pH-value of bupivacaine 0.25% was 6.0 and that of bupivacaine 0.125% 6.3. Even so the differences of the pH-values between the two solutions are rather small, a possible key to the problem of the dose response relationship, concerning tachyphylaxis, can be suggested. But further investigations have to show, whether the use of local anaesthetic solutions, being stable at pH-values of 7 to 8, makes the continuous epidural analgesia easier to handle for postoperative pain relief.
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10,000,049
Axis stability in toric soft lenses.
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10,000,050
[Anaesthesia in juvenile muscular atrophy (Kugelberg-Welander syndrome) (author's transl)].
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10,000,051
A ten-year-old boy with Kugelberg-Welander syndrome was referred to the Ear-Nose- and Throat department for an emergency tracheostomy operation. There was no time for premedication. General anaesthesia was performed with a combination of thiopentone, halothane and nitrous oxide. The patient was awake soon after the operation but developed severe respiratory depression necessitating mechanical ventilation for 12 hours. The causes of the respiratory depression and the anaesthetic problems presented by these cases are discussed.
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10,000,052
Extended wear contact lenses for aphakic correction, experiences with the Cooper Permalens, a preliminary report.
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10,000,053
[Headache after spinal analgesia with reference to the type of analgesic agent used (author's transl)].
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10,000,054
The incidence and localization of headache after spinal analgesia were studied by means of a questionnaire. The case material comprised 503 spinal analgesias carried out with a 4% hyperbaric and a 2% isobaric solution of mepivacaine respectively and with 0.5% isobaric solution of bupivacaine. The use of the 4% solution of mepivacaine was followed by an increased incidence of prolonged dull headache in the occipital region. The observations suggest that the occurrence of headache after spinal analgesia may also depend on the type of analgesic agent employed.
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10,000,055
Modification of available arginine residues in proteins by p-hydroxyphenylglyoxal.
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10,000,056
Retrospective study of retinal complications with posterior chamber lenses.
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10,000,057
Laboratory evaluation of chemical disinfection of soft contact lenses. II. Fungi as challenge organisms.
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10,000,058
The early development of corticobulbar and corticospinal systems. Studies using the North American opossum.
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10,000,059
The North American opossum is born 12 days after conception and is therefore available for experimental manipulation in an immature state. We have used the opossum to study the growth of cortical axons into the brainstem and spinal cord and have obtained evidence that such growth occurs in an orderly fashion. Cortical axons reach the ventral mesencephalon 12 days after birth and some of them have grown into the caudal medulla where they decussate by 23 days. At the latter stage immature cortical axons also distribute to the midbrain tegmentum, the basilar pons, the inferior olive and the hilum of the nucleus cuneatus. Cortical axons first enter the spinal cord about 30 days after birth where they are present in the white matter before growing into the dorsal horn. The forelimb placing reaction does not develop until well after cortical axons have reached cervical levels. Axons from the cerebral cortex grow into the spinal cord before there is evidence for cortical innervation of either the red nucleus or the bulbar reticular formation and well before pyramidal cells of the neocortex are mature. The relatively late development of corticospinal and corticobulbar systems contrasts markedly with the early growth of bulbospinal axons.
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10,000,060
[A comparison of anaesthetic awakening with out-patients treated by maxillo-facial surgery using 4 different anaesthetic techniques (author's transl)].
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10,000,061
To estimate and compare the awakening period following 4 different anaesthetic techniques (enflurane and halothane and two intraveinous anaesthetic substances: propanidide and althesin), the authors examined 120 outpatients who had undergone maxillo-facial surgery distributed over 4 sample groups of 30 each. A statistical analysis of the responses to psycho-dianostic tests has not enabled the authors to decide which anaesthetic ambulatory technique is preferable.
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10,000,062
Early extubation versus prophylactic ventilation in the high risk patient: a comparison of postoperative management in the prevention of respiratory complications.
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10,000,063
To evaluate whether prophylactic ventilation during the early postoperative period diminishes pulmonary complications, 35 high risk, elderly patients undergoing major, elective abdominal aortic reconstruction were prospectively randomized into either an early extubation group or a prophylactic ventilation group. The 17 patients assigned to the prophylactic ventilation group received mechanical ventilation by assist/control mode until 8 a.m. of the first postoperative day. The 17 patients assigned to the early extubation group were extubated after the operation as soon as they could maintain a pH of 7.35, with a spontaneous respiratory rate of less than 30. Preoperative measurements of functional residual capacity, intrapulmonary shunt, and oxygen delivery were compared to similar measurements during the initial two postoperative days. There were no significant differences between the groups with respect to age, length of operation, duration of anesthesia, operative blood loss, intraoperative fluid administration, or number of intraoperative transfusions. Patients in the prophylactic ventilation group were ventilated for an average of 18.3 +/- 0.5 hours. Patients in the early extubation group were ventilated for an average of 3.3 +/- 0.5 hours (p < 0.0005). No patient in either group required reintubation. Intrapulmonary shunt and oxygen delivery were not significantly different between the groups at any time during the study period. There was no mortality or significant morbidity in either group. These findings suggest that in high risk surgical patients, prophylactic ventilation, per se, may not diminish respiratory complications or improve gas exchange.
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10,000,064
[Chronic non-specific disease of the respiratory system and measurable alterations in workers in the chromium-plating industry (author's transl)].
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10,000,065
Lung function test performed on 26 chromium plating workers showed a high prevalence of obstructive disease and of change in DLCO. The connection between lung function impairment and occupational exposure to chromium is suggested by the relationship between respiratory changes and biological indices of chromium absorption. The prevalence and the severity of ventilatory impairment also show an increasing trend with the duration of the exposure, while the smoking habitus seems not to be important.
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10,000,066
[Tibial periostal graft in the repair of the primary cleft palate: preliminary report of a new technique (author's transl)].
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10,000,067
Reconstruction of the oral plane of a primary cleft palate using tibial periostal graft at the primary repair stage seems a highly appealing technique: -- the osteogenic power of the periosteum used as a free transplant has been demonstrated long ago (Ollier, Axhausen); -- two requisites must be filled when primary palate repair is undertaken: maintainance of the nasal fossa size and maintenance of the palatal fibromucosa that must be not submitted to any traction whatsoever, otherwise endognathia will arise. A vast, tight and strong periostal plane will be obtained with the periostal graft, the latter bringing also bone to the cleft. Better still, such a periostal graft can be extended backwards over the entire length of the cleft bony palate which will subsequently create a situation requiring simple soft palate repair.
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10,000,068
[Hyperselective angiography in the study of spinal diseases (author's transl)].
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10,000,069
We report about a new angiographic technique, spinal angiography, its indications and complication. Spinal angiography is clearly essential for the diagnosis in retro or intramedullary arterio-venous malformations and for metameric angiomatosis with neurological involvement.
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10,000,070
Enhancement of relaxation rate with paramagnetic contrast agents in NMR imaging.
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10,000,071
Enhancement of spin-lattice relaxation using oral ferric chloride and using inhaled oxygen is illustrated. A 0.06% solution of ferric chloride reduced the spin-lattice relaxation time in the fundus of the stomach from 730 ms to 285 ms. Ferric chloride may be useful as a bowel-labeling agent. In 5 volunteers inhalation of 100% oxygen decreased the mean observed spin-lattice relaxation time of blood within the left ventricular cavity. Although the change was small, it may have important uses in monitoring metabolic processes.
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10,000,072
A study of the influence of the ambient microflora on the structure of lung alveolar macrophages and an ultrastructural comparison of lung and peritoneal macrophages in germ-free and conventionally reared mice.
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10,000,073
In order to investigate quantitatively and objectively the influence of the normal microbial flora on the ultrastructure of the alveolar macrophage, three groups of mice were studied stereologically: germ-free (GF), conventionally reared under non sterile isolation conditions (IC), and conventionally reared in an open environment (OC). The alveolar macrophages of GF mice possess a smaller mitochondrial compartment, possibly with fewer organelles, than the macrophages of conventional mice. Other influences of the normal microflora on alveolar macrophage substructure are obscured by the effects of nonmicrobial stimuli such as droplets of lung surfactant. No previous comparison exists of alveolar and peritoneal macrophage ultrastructure. Lung macrophages are larger than the phagocytes of the peritoneum, but the difference in size is much less than is commonly believed. Alveolar macrophages are rounder than peritoneal macrophages, and exhibit much less rough endoplasmic reticulum (RER) as well as differences in mitochondrial morphometry. No difference in mitochondrial volume fraction exists between the two types of macrophage even though alveolar macrophages represent the extreme of aerobic adaptation in the mononuclear phagocyte system. Phagosomes occupy a significant fraction of cellular volume only in the alveolar macrophages. Moreover alveolar phagocytes contain fewer but larger represent the first objective, quantitative structural evidence confirming the common belief that alveolar macrophages experience greater physiological stimulation than peritoneal macrophages. The normal microflora accounts for only a small proportion of the differing degree of stimulation exerted on the two types of macrophage.
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10,000,074
An in-house industrial counseling program: the Northwestern Bell Telephone Company experience.
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10,000,075
Development of a counseling program at Northwestern Bell Telephone in the state of Iowa began in 1970. Since its inception, the program has expanded to assist nearly 2000 individuals per year with varying problems. It is not the first counseling program for employees (other programs are described in the paper), but it is unique in its availability to all employees in the state, with counselors strategically placed in the major districts of the Bell System. Because of its concern for human resources, the company supported the medical department in establishing the counseling program. The management has been supportive and noninterfering. The numbers of employees using the program and their responses to questionnaires indicate the need for the service. The advantages and costs of an in-house counseling service are discussed.
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10,000,076
Methodological and practical issues related to shiftwork research.
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10,000,077
This paper cites inconsistencies in the current literature regarding the health impact of shiftwork and suggests that these disparities may be attributed, in part, to shortcomings in the nature and reporting of cross-sectional field research. Selected methodological (e.g., differential accretion, cross-over) and practical (e.g., definition of independent and dependent variables) problems in the design and communication of shiftwork investigations are discussed and strategies are provided for their solution.
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10,000,078
The emerging role of the occupational physician in preventive medicine, health promotion and health education.
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10,000,079
Localized fatigue in accounting-machine operators.
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10,000,080
The foundation: qualitative research and occupational therapy.
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10,000,081
[Intracapsular vascular hamartoma. Description of a case].
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10,000,082
[At the beginning of the last third in the fight against tuberculosis in Switzerland (author's transl)].
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10,000,083
[Particular aspects in the rehabilitation of patients with neurological diseases (author's transl)].
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10,000,084
[Disorders of motility of the anal sphincter apparatus. 16 November 1980, Berne].
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10,000,085
[Dermatologic entomology. The practical medical importance of mites and insects in Switzerland and its surrounding regions. 13. Vespidae/wasps].
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10,000,086
[Dermatologic entomology. The practical medical importance of mites and insects in Switzerland and its surrounding regions. 15. Coleoptera/beetles].
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10,000,087
[A case from general practice (6)].
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10,000,088
[Family doctors and acute myocardial infarction (author's transl)].
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10,000,089
[Basic problems of antiarrhythmic treatment (author's transl)].
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10,000,090
[Anterior cervical discectomy for treatment of disc herniation (author's transl)].
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10,000,091
[Baker's cyst--disease or symptom?].
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10,000,092
[Asymptomatic hyperuricaemia: to treat or not to treat? (author's transl)].
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10,000,093
[The acute arterial occlusion of the lower limbs (author's transl)].
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10,000,094
[Radiology of colon and colonoscopy (author's transl)].
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10,000,095
Computer-videotape study of functional anatomy: a preliminary report and bibliography.
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-0.0018143401248380542, 0.038639530539512634, 0.02958434820175171 ]
10,000,096
Septic diskitis: report of case and review of the literature.
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10,000,097
Diagnosis of fever of unknown origin.
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10,000,098
Exploratory thoracotomy and postmortem evaluation: III. Clinical experience with diaphragmatic excursion.
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10,000,099
Current status of bilirubin encephalopathy.
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