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Trends in Chemistry
|
6_2
|
Which of the following options best describe the cover image?
|
MAC_Bench/Cell/Cover/Trends in Chemistry/6_2.png
|
A
|
BURP domain peptide cyclases (BpCs) represent a newly emerging class
of copper enzymes that catalyze the oxidative macrocyclization of peptides in plants,
offering exciting potential for advances in plant biochemistry and biotechnology.
In their
Opinion article, Hematian and Noyon discuss the recent breakthroughs in understanding
the sequence, structure, and function of BpCs, along with their proposed chemistry.
They offer potential mechanistic models and highlight critical structural aspects
that
could guide future research into BpCs' reactivity and catalytic mechanisms. Artwork
credit: Shabnam Hematian & M. Rafi ul O. K. Noyon
|
MAC_Bench/Cell/Story/Trends in Chemistry/6_2.txt
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groundtruth
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6_2.txt
|
In this special issue of Trends in Chemistry, we wrap up our inaugural content by continuing to address big questions in chemistry.
We introduce 14 new articles outlining key topics in chemistry including: lithium-metal
batteries; electrochemical water splitting; light hydrocarbon separations; glycosidic
bond hydroxylation; and two dimensional materials, just to name a few. The cover image
is a continuation of the Issue 1 cover but now with a collection of molecules, structures
and reactions primarily found within this issue.
|
MAC_Bench/Cell/Story/Trends in Chemistry/1_9.txt
|
clip
|
1_9.txt
|
The cover image illustrates nature-inspired biocatalytic photosynthesis that synthesizes
valuable chemicals and fuels using sunlight. Solar-driven collaborative catalysis
integrates the best attributes of photocatalysis and redox biocatalysis for sustainable
chemical synthesis. Photocatalytic molecules/materials harvest renewable solar light
to activate oxidoreductases with exceptional reaction selectivities. On pages 133–146
of this issue, Jinhyun Kim and Chan Beum Park review recent advances in collaborative
catalysis for solar biosynthesis. Image credit: Jinhyun Kim (Korea Advanced Institute
of Science and Technology).
|
MAC_Bench/Cell/Story/Trends in Chemistry/5_12.txt
|
vitg
|
5_12.txt
|
In this special issue of Trends in Chemistry, we highlight the design and emerging catalytic applications of transition metals
and their complexes in organic and organometallic chemistry, including: C-C bond formation,
C-H functionalization, branch-selective olefin hydroarylation, carbon-dioxide methanation,
and chemo-catalytic cellulose conversion to ethanol. On pages 510–523 of this issue,
Rueping and colleagues discuss visible light-induced excited-state transition-metal
catalysis. In contrast to metal/photoredox dual catalysis which has garnered significant
attention as a bond-forming platform, excited-state transition-metal catalysis employs
a single metal complex as both the photo- and cross-coupling catalyst, offering potential
efficient and economic C-C bond formation.
|
MAC_Bench/Cell/Story/Trends in Chemistry/1_5.txt
|
ave_1
|
1_5.txt
|
train
|
NATURE MEDICINE
|
30_8
|
Which of the following options best describe the cover image?
|
MAC_Bench/Nature/Cover/NATURE MEDICINE/30_8.png
|
D
|
Medicine in the digital age
As Nature Medicine celebrates its 25th anniversary, we bring our readers a special Focus on Digital Medicine that highlights the new technologies transforming medicine and healthcare, as well as the related regulatory challenges ahead.
See Focus
Image credit: Peter Crowther. Cover design: Erin Dewalt
|
MAC_Bench/Nature/Story/NATURE MEDICINE/25_12.txt
|
vith
|
25_12.txt
|
30th anniversary issue: the Future of Medicine
As Nature Medicine turns 30 years old, we will, throughout 2025, be looking at the future of medicine. In this first issue, we turn our attention to next-generation drug discovery.
Image and cover design: Alex Whitworth
|
MAC_Bench/Nature/Story/NATURE MEDICINE/31_1.txt
|
clip
|
31_1.txt
|
This month Nature Medicine features a collection of articles focusing on regenerative medicine (pp 814880). Cover image: "My Life as a Hill" by Pamela Goode
|
MAC_Bench/Nature/Story/NATURE MEDICINE/20_5.txt
|
vitg
|
20_5.txt
|
Heatwave mortality
In this issue, Xi et al. use data from a cohort of Chinese adults 65 years of age and older to show that variables related to functional aging are more predictive of increased heat-related mortality risk than is age alone. The cover highlights both the rise in global temperatures, via the color transition, and the importance of identifying those populations most vulnerable to climate change in order to inform targeted adaptation strategies.
See Xi et al.
Image: Yan Dong, Lanxi Xiao, Qiong Wu and Xiuge Zhang, Tsinghua University; at-large designers, Xuezhen Jin and Dezun Ji. Cover design: Marina Corral Spence
|
MAC_Bench/Nature/Story/NATURE MEDICINE/30_8.txt
|
groundtruth
|
30_8.txt
|
train
|
ACS Applied Bio Materials
|
2024_9
|
Which of the following options best describe the cover image?
|
MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2024_9.png
|
A
|
Discarded human eye lens proteins post cataract surgery developed as thin films capable of ion conduction: potential applications as eco-friendly flexible solid polymer electrolytes.
|
MAC_Bench/ACS/Story/ACS Applied Bio Materials/2024_9.txt
|
groundtruth
|
2024_9.txt
|
A newly designed DNA aptamer switch (keyhole on door) can reconfigure when binding to lead ions (purple spheres). The aptamer switch (aptaswitch) is used to detect lead ions using the fluorescent signal obtained on reconfiguration (open aptaswitches on other side of door). Cover art designed and created by Arun Richard Chandrasekaran.
|
MAC_Bench/ACS/Story/ACS Applied Bio Materials/2022_2.txt
|
vitg
|
2022_2.txt
|
The cover image depicts the semiconducting oligomer amphiphiles (OPV-PEG)-based activatable nanoprobes for in vivo imaging of biothiols. OPV-PEG is composed of a hydrophobic semiconducting segment that serves as both the signal source and the sensing moiety for biothiols, and the hydrophilic poly(ethylene glycol) (PEG) side chains to provide the water-solubility. OPV-PEG can self-assemble with a near-infrared (NIR) photosensitizer to emit both NIR fluorescence and afterglow luminescence. In the presence of biothiols in living animals, the NIR fluorescence of this nanoprobe is turned on, but the afterglow signal remains the same, which permits precise tracking of the probe location while detecting biothiols.
|
MAC_Bench/ACS/Story/ACS Applied Bio Materials/2018_3.txt
|
clip
|
2018_3.txt
|
The cover art depicts the photoresponsive conjugated polymer materials for applications in cell imaging, photodynamic therapy of cancer, and bioelectronic devices in a combined platform. Functionalization of the donor−acceptor-type polymer with a specific cellular targeting unit leads to uptake into tumor cell for fluorescent imaging. The photoresponsive polymer material could sensitize the molecular oxygen to generate reactive oxygen species leading to tumor cell death, while polymer materials can be modified to electrolytes to build up bioelectronic devices used for improving biocatalysis (photolysis of water to oxygen) and photoelectric conversion.
|
MAC_Bench/ACS/Story/ACS Applied Bio Materials/2018_6.txt
|
vith
|
2018_6.txt
|
train
|
ACS Measurement Science Au
|
2022_2
|
Which of the following options best describe the cover image?
|
MAC_Bench/ACS/Cover/ACS Measurement Science Au/2022_2.png
|
A
|
Despite its global importance in controlling the world's carbon dioxide levels, there is a lot we do not know about calcite dissolution. By studying the dissolution reaction at the single particle scale, we reveal the process to be limited by the diffusion of ions away from the mineral interface.
|
MAC_Bench/ACS/Story/ACS Measurement Science Au/2022_2.txt
|
groundtruth
|
2022_2.txt
|
Seeing is not believing: The weak transient current signals of single-particle collisions we recorded are often distorted by amplifiers' filter and the noise. It seems like we “see” signals from the reflection in the water. The “ripples” and “waving shadow” mask our “believing” of the dynamic nature of individual entities.
|
MAC_Bench/ACS/Story/ACS Measurement Science Au/2022_3.txt
|
ave_3
|
2022_3.txt
|
Almost a decade of developments: Substrate-integrated hollow waveguides for advanced gas sensing systems
|
MAC_Bench/ACS/Story/ACS Measurement Science Au/2021_1.txt
|
clip
|
2021_1.txt
|
This cover highlights the 2024 Rising Stars in Measurement Science. These nineteen early-career scientists from across the globe are making significant contributions to the field of measurement science, in spectroscopy, mass spectrometry, electrochemistry, and separations.
|
MAC_Bench/ACS/Story/ACS Measurement Science Au/2025_1.txt
|
ave_2
|
2025_1.txt
|
test
|
CELL RESEARCH
|
35_1
|
Which of the following options best describe the cover image?
|
MAC_Bench/Nature/Cover/CELL RESEARCH/35_1.png
|
B
|
The cover depicts a newly built elevated highway (replicating DNA) that is damaged (mismatch). A worker (MutS-MutL complex) identifies the damage and communicates with the repair department (Exo1) to fix the problem. The columns (buildings) represent chromatin remodeling and DNA metabolic proteins. Designed by Yipin Wu.See page 542-553 by Janice Ortega et al. for details.
Designed by Yipin Wu
|
MAC_Bench/Nature/Story/CELL RESEARCH/31_8.txt
|
ave_3
|
31_8.txt
|
The dual effects of glucocorticoids (GCs) are illustrated by bees. Left, low levels of GCs bind to the canonical high-affinity GC receptor (GR, the flower producing honey), mediating physiological and therapeutic effects. Right, high levels of GCs can also bind to the low-affinity receptor, tau, leading to bone loss and demonstrating pathological effects. See page 23–44 by Wenyu Fu et al. for details.
|
MAC_Bench/Nature/Story/CELL RESEARCH/35_1.txt
|
groundtruth
|
35_1.txt
|
The dual effects of glucocorticoids (GCs) are illustrated by bees. Left, low levels of GCs bind to the canonical high-affinity GC receptor (GR, the flower producing honey), mediating physiological and therapeutic effects. Right, high levels of GCs can also bind to the low-affinity receptor, tau, leading to bone loss and demonstrating pathological effects. See page 23–44 by Wenyu Fu et al. for details.
|
MAC_Bench/Nature/Story/CELL RESEARCH/35_2.txt
|
clip
|
35_2.txt
|
The cover image illustrates the aluminum (Al) ion receptor ALR1 (Beacon Tower)that senses toxic aluminum ions, inducing reactive oxygen species (ROS; smoke) generation and accumulation of STOP1 (commander),thereby activating organic acid anion (arrow) secretion to detoxify Al. See page 281–294 by Zhong Jie Ding et al. for details.
|
MAC_Bench/Nature/Story/CELL RESEARCH/34_9.txt
|
ave_2
|
34_9.txt
|
train
|
ACS Chemical Biology
|
2024_4
|
Which of the following options best describe the cover image?
|
MAC_Bench/ACS/Cover/ACS Chemical Biology/2024_4.png
|
B
|
DOI: 10.1021/cb1003652) reveal the biosynthetic pathway of a key autoinducer, CAI-1 associated with the life cycle and virulence of human pathogen, Vibrio cholerae. Cover art designed by Mable Fok.
|
MAC_Bench/ACS/Story/ACS Chemical Biology/2011_9.txt
|
clip
|
2011_9.txt
|
Protein abnormal S-palmitoylation is associated with a variety of diseases, but rare effective S-palmitoylation inhibitors have been reported. Targeting the PATs and
|
MAC_Bench/ACS/Story/ACS Chemical Biology/2024_4.txt
|
groundtruth
|
2024_4.txt
|
The cover picture highlights work with protein farnesyltransferase whose specificity was probed by screening peptide libraries prepared via SPOT synthesis. These experiments provide insights into the relationship between isoprenoid structure and protein specificity and reveal significant differences between prenyltransferases from different species that may be useful for drug design. Art designers: Josh Ochocki and Yen-Chih Wang
|
MAC_Bench/ACS/Story/ACS Chemical Biology/2014_5.txt
|
ave_1
|
2014_5.txt
|
This cover highlights the simultaneous observation of unusual -1 and -2 ribosomal frameshiftings on a slippery mRNA , via a novel mechanomagnetic detection of magnetic DNA rulers and centrifugal forces. Image Credit: Shoujun Xu
|
MAC_Bench/ACS/Story/ACS Chemical Biology/2017_7.txt
|
vith
|
2017_7.txt
|
train
|
Trends in Biotechnology
|
42_10
|
Which of the following options best describe the cover image?
|
MAC_Bench/Cell/Cover/Trends in Biotechnology/42_10.png
|
D
|
Trends in Biotechnology is celebrating its 30th year of publishing exciting reviews
in biotechnology. The coverimage shows microbes taking advantage of the occasion.
Cover image made by Julien Husson and coverdesigned by Paige Shaklee.
|
MAC_Bench/Cell/Story/Trends in Biotechnology/31_11.txt
|
clip
|
31_11.txt
|
On pages 448–458, Zahra Hamrang and colleagues review emerging trends and novel technologies
that offer a promising potential for accurately predicting and profiling protein aggregation
at various stages of biopharmaceutical product design. The cover image is from iStockPhoto
and design is by Paige Shaklee.
|
MAC_Bench/Cell/Story/Trends in Biotechnology/31_5.txt
|
vitg
|
31_5.txt
|
Trends in Biotechnology is celebrating its 30th year of publishing exciting reviews
in biotechnology. The coverimage shows microbes taking advantage of the occasion.
Cover image made by Julien Husson and coverdesigned by Paige Shaklee.
|
MAC_Bench/Cell/Story/Trends in Biotechnology/31_10.txt
|
ave_2
|
31_10.txt
|
The rising threat of multi-drug resistant infections has brought
bacteriophage into the spotlight, with advances in sequencing technologies and genetic
engineering techniques enabling rapid development of engineered phage therapeutics.
In pages 326–338 of this issue, Schmitt and colleagues discuss applications of designer
phage containing recombinant gene payloads to enhance antimicrobial activity and
manipulate the microbiome. Cover image from Jason Whitley, Senior Instructional
Designer, BTEC.
|
MAC_Bench/Cell/Story/Trends in Biotechnology/42_10.txt
|
groundtruth
|
42_10.txt
|
test
|
Lab Animal
|
53_4
|
Which of the following options best describe the cover image?
|
MAC_Bench/Nature/Cover/Lab Animal/53_4.png
|
D
|
Putting together genome puzzles
Assembling a genome is not unlike assembling a puzzle. As sequencing technologies continue to advance, genomic puzzles are becoming easier to put together. That’s facilitating the sequencing of many different animal species, some already common to the lab and others much more novel.
See Eisenstein
Image: Thanit Weerawan/Moment/Getty. Cover design: Erin Dewalt
|
MAC_Bench/Nature/Story/Lab Animal/48_8.txt
|
clip
|
48_8.txt
|
Precision genome editing in zebrafish
DNA base editors are promising tools that can induce point mutations at desired sites in the genome. However, a major limitation in applying such systems is the prerequisite of a protospacer adjacent motif (PAM) sequence next to the target site. In a News and Views, Pratishtha Varshney and Gaurav Varshney discuss how SpRY-based DNA base editors, with highly flexible PAM recognition, greatly expand targetable sites in the genome and the possibilities for disease modeling in zebrafish.
See Varshney & Varshney,
COVER IMAGE: Marina Spence. COVER DESIGN: Marina Spence.
|
MAC_Bench/Nature/Story/Lab Animal/51_1.txt
|
ave_3
|
51_1.txt
|
Reporting metadata in animal research
Data sharing allows data to be reused in other analyses, avoiding resources (and animals) being wasted in unnecessary replication studies. A new Perspective proposes a minimal metadata set to enable data sharing and repurposing in animal research, contributing to the principle of reduction.
See Moresis et al.
Cover image: Debbie Maizels. Cover design: Debbie Maizels.
|
MAC_Bench/Nature/Story/Lab Animal/53_10.txt
|
vith
|
53_10.txt
|
Exon-skipping gene editing in marmoset
Many disease-related genes cause perinatal death in genetically altered homozygous nonhuman primates (NHP). As NHP resources are limited, efficient methods are necessary to create new genetic models. In a new Article, Sasaki et al. show that using Platinum TALEN gene-editing technology in oocytes is an effective method for producing genetically modified heterozygous marmosets by exon skipping.
See Sato et al.
Cover image: Perception7 / iStock / Getty Images Plus and Marina Spence. Cover design: Marina Spence.
|
MAC_Bench/Nature/Story/Lab Animal/53_4.txt
|
groundtruth
|
53_4.txt
|
test
|
Science Signaling
|
2007_406
|
Which of the following options best describe the cover image?
|
MAC_Bench/Science/Cover/Science Signaling/2007_406.png
|
C
|
COVER This week's issue features a Perspective on how the neuropeptide VGF is involved in the mood-elevating effects of exercise and other stimuli. [Image: Jupiter Images]
|
MAC_Bench/Science/Story/Science Signaling/1_18.txt
|
vith
|
1_18.txt
|
ONLINE COVER This week features a Research Resource that identifies transcriptional links between chronic pain, stress and depression. The image shows a person suffering from stress and depression. [Image: OcusFocus/iStockphoto]
|
MAC_Bench/Science/Story/Science Signaling/10_471.txt
|
clip
|
10_471.txt
|
COVER This week features a Perspective on how day length modulates the behavioral effects of estrogens. [Image: J. Foxx/Getty Images]
|
MAC_Bench/Science/Story/Science Signaling/2007_406.txt
|
groundtruth
|
2007_406.txt
|
ONLINE COVER This week features a Research Article that describes how S-nitrosothiols limit signaling downstream of G protein–coupled receptors and thus could protect against ischemic injury in the heart. The image shows a man experiencing chest pains. [Image: Jeremy Sterk/iStockphoto]
|
MAC_Bench/Science/Story/Science Signaling/6_299.txt
|
vitg
|
6_299.txt
|
train
|
Nature Metabolism
|
6_2
|
Which of the following options best describe the cover image?
|
MAC_Bench/Nature/Cover/Nature Metabolism/6_2.png
|
A
|
Phages and food addiction
Bacteriophages in the gut microbiome are shown to regulate food addiction traits by modulating tryptophan and tyrosine metabolism in the host. The image depicts bacteriophages attacking a bacterial cell.
See Castells-Nobau et al.
Image credit: MattLphotography / Alamy Stock Photo. Cover design: Allen Beattie.
|
MAC_Bench/Nature/Story/Nature Metabolism/6_2.txt
|
groundtruth
|
6_2.txt
|
FASN cuts stress
In this issue of Nature Metabolism, Wei et al. identify a non-fatty acid synthesis function for FASN in suppressing diverse aspects of stress responses through a mechanism that involves FASN cleavage. Depicted are anesthetized C. elegans following stressful conditions.
See Wei et al.
Image: Hai Wei, UT Southwestern Medical Center. Cover Design: Thomas Phillips.
|
MAC_Bench/Nature/Story/Nature Metabolism/6_12.txt
|
vitg
|
6_12.txt
|
A gut microbiome-derived metabolite promotes obesity
Delta-valerobetaine is identified as a gut microbiome-derived metabolite that correlates with adiposity in humans, while exacerbating diet-induced obesity in mice.
See Liu, Owens, Saeedi et al.
Image: nobeastsofierce Science / Alamy Stock Photo. Cover Design: Thomas Phillips.
|
MAC_Bench/Nature/Story/Nature Metabolism/3_1.txt
|
vith
|
3_1.txt
|
Untangling the central and peripheral GLP-1 signalling circuitry
Brierley et al. find that central and peripheral GLP-1 systems suppress eating via independent gut–brain circuits.
See Brierley et al.
Image: Guillaume de Lartique, University of Florida. Cover Design: Thomas Phillips.
|
MAC_Bench/Nature/Story/Nature Metabolism/3_11.txt
|
clip
|
3_11.txt
|
train
|
Nature Chemical Biology
|
20_3
|
Which of the following options best describe the cover image?
|
MAC_Bench/Nature/Cover/Nature Chemical Biology/20_3.png
|
A
|
Respiration guides living materials
Graham et al. developed engineered living materials with controllable mechanic properties in response to environmental stimuli. This was achieved by programming bacteria (orange) embedded in the hydrogel matrix with genetic logic circuits to control the expression of MtrC (foreground), a membrane-associated protein that regulates the microbial respiration process.
See Graham et al. and Atkinson
Image: Ismar Miniel Mahfoud, The University of Texas at Austin; protein structure from PDB; PDB ID: 4LM8. Cover design: Alex Wing
|
MAC_Bench/Nature/Story/Nature Chemical Biology/20_3.txt
|
groundtruth
|
20_3.txt
|
The cover depicts numerous extracellular membrane vesicles associated with a long cellular process on a neural stem cell, imaged by a scanning electron microscope. Isolated extracellular vesicles were found to be metabolically active, and metabolomics analysis revealed the presence of asparaginase activity attributed to the enzyme asparaginase-like 1. Cover design by Erin Dewalt, based on an image generated by Jose Manuel Garcia-Verdugo and Clara Alfaro-Cervello. Article, p951; News & Views, p924
|
MAC_Bench/Nature/Story/Nature Chemical Biology/13_4.txt
|
clip
|
13_4.txt
|
20 years of Nature Chemical Biology
This month, Nature Chemical Biology celebrates 20 years with a selection of pieces that highlight some landmarks in chemical biology, examine current challenges and outline future directions. The cover image depicts a gel as a representation of the foundational techniques that underpin many advances in chemical biology.
See Editorial
Image: filo / DigitalVision Vectors / Getty Images. Cover design: Alex Wing
|
MAC_Bench/Nature/Story/Nature Chemical Biology/21_2.txt
|
vitg
|
21_2.txt
|
The cover depicts an acidic patch of ubiquitin (purple) on a chromatin fiber (gray structure) displayed on a background showing cross-peaks from hydrogen-deuterium exchange nuclear magnetic resonance analysis. The image is based on PDB 1UBQ and EMD 2600 visualized with the program Chimera. Cover design by Erin Dewalt, based on an image created by Galia Debelouchina. Article, p105
|
MAC_Bench/Nature/Story/Nature Chemical Biology/13_12.txt
|
ave_1
|
13_12.txt
|
train
|
Industrial & Engineering Chemistry Research
|
2024_36
|
Which of the following options best describe the cover image?
|
MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_36.png
|
D
|
This Special Issue of I&EC Research honors the contributions of Professor Joan F. Brennecke to the field of chemical engineering and environmental separation processes using ionic liquids and supercritical fluids.
|
MAC_Bench/ACS/Story/Industrial & Engineering Chemistry Research/2022_19.txt
|
vitg
|
2022_19.txt
|
: Graphics used on this cover have been selected from the following highlighted papers: T. Sun et al., “Syngas Conversion to Aromatics over the Co2C‑Based Catalyst and HZSM‑5 via a Tandem System” (DOI: 10.1021/acs.iecr.0c00237); W. Peng et al., “Guanidine-Functionalized Amphiphilic Silica Nanoparticles as a Pickering Interfacial Catalyst for Biodiesel Production” (DOI: 10.1021/acs.iecr.9b06097); and H. Yang et al., “Highly Efficient Production of 5‑Methoxymethylfurfural from Fructose in Dimethyl Sulfoxide/Amberlyst-15 Catalytic System” (DOI: 10.1021/acs.iecr.9b06392).
|
MAC_Bench/ACS/Story/Industrial & Engineering Chemistry Research/2020_42.txt
|
clip
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2020_42.txt
|
Graphics used on this cover have been selected from the following highlighted papers: H. Zhou et al., “Synergetic Bimetallic NiCo/CNT Catalyst for Hydrogen Production by Glycerol Steam Reforming: Effects of Metal Species Distribution” (DOI: 10.1021/acs.iecr.0c01258); X. Chen et al., “Lignocellulosic Biomass Upgrading into Valuable Nitrogen-Containing Compounds by Heterogeneous Catalysts” (DOI: 10.1021/acs.iecr.0c01815); Y. Wu et al., “Light Color Dihydroxybenzophenone Grafted Lignin with High UVA/ UVB Absorbance Ratio for Efficient and Safe Natural Sunscreen” (DOI: 10.1021/acs.iecr.9b06970); and T. Gao et al., “Base-Free Aerobic Oxidation of 5‑Hydroxymethylfurfural on a Ru(0) Center in Cooperation with a Co(II)/Co(III) Redox Pair over the One-Pot Synthesized Ru−Co Composites” (DOI: 10.1021/acs.iecr.0c00937).
|
MAC_Bench/ACS/Story/Industrial & Engineering Chemistry Research/2020_14.txt
|
vith
|
2020_14.txt
|
high hydrogen permeable ZIF-8 membranes offer great application potential for extracting hydrogen from coke oven gas.
|
MAC_Bench/ACS/Story/Industrial & Engineering Chemistry Research/2024_36.txt
|
groundtruth
|
2024_36.txt
|
val
|
Nature Reviews Neurology
|
20_11
|
Which of the following options best describe the cover image?
|
MAC_Bench/Nature/Cover/Nature Reviews Neurology/20_11.png
|
A
|
Inflammasome scaffolds, inspired by the Review on p67.
Cover design: Philip Patenall
|
MAC_Bench/Nature/Story/Nature Reviews Neurology/20_11.txt
|
groundtruth
|
20_11.txt
|
Adaptive and maladaptive myelination, inspired by the Review on p735.
Cover design: Philip Patenall.
|
MAC_Bench/Nature/Story/Nature Reviews Neurology/18_1.txt
|
clip
|
18_1.txt
|
Seizures in Alzheimer disease, inspired by the Review on p162.
Cover design: Philip Patenall
|
MAC_Bench/Nature/Story/Nature Reviews Neurology/20_10.txt
|
vith
|
20_10.txt
|
HIV and the brain, inspired by the Consensus Statement on p424.
Cover design: P.Patenall
|
MAC_Bench/Nature/Story/Nature Reviews Neurology/19_6.txt
|
vitg
|
19_6.txt
|
train
|
Caner Cell
|
42_9
|
Which of the following options best describe the cover image?
|
MAC_Bench/Cell/Cover/Caner Cell/42_9.png
|
B
|
On the cover: Defeating a complex disease like cancer will require a united, concerted
effort by different types of people from diverse backgrounds who can bring together
distinctive experiences and ways of thinking. This issue of Cancer Cell features Voices, Letter, and Commentary pieces discussing the importance of diversity
and immigration for the future of cancer research.
|
MAC_Bench/Cell/Story/Caner Cell/38_4.txt
|
clip
|
38_4.txt
|
On the cover: In this issue of Cancer Cell, two papers by Barisic et al. and Deng et al. evaluate how mutations in components of the BAF complex lead to the development of
B cell malignancies. In the cover, Barisic et al. demonstrate that ARID1A is required
for continuous eviction of nucleosomes, facilitating the sequential binding of transcription
factors necessary for safeguarding germinal center B cell fate towards plasma cells.
The cover image symbolizes ARID1A as Sisyphus, exerting significant effort and energy
to push boulders uphill, analogous to the BAF complex and ARID1A using energy from
ATP hydrolysis for nucleosome eviction. Birds in the image symbolize the antibodies
produced by plasma cells when ARID1A effectively remodels nucleosomes. Credit: Art
by Inmywork Studio.
|
MAC_Bench/Cell/Story/Caner Cell/42_9.txt
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groundtruth
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42_9.txt
|
On the cover: Immune cells are major defenders of our body but are often turned into
protectors (symbolized by the hairy cell holding a shield) of tumors (symbolized by
the crab) as well as promoting tumor progression. Decades of research in immunology
have led to the development of many immunotherapeutic approaches (symbolized by the
cells holding swords), some of which have shown encouraging clinical results in recent
years. This issue presents three Perspectives, two Articles, and three Previews illustrating
the progress in cancer immunotherapy and is published in conjunction with the April
Trends in Immunology special issue on immunity and cancer. Cover concept by Seth B. Coffelt and Karin
E. de Visser; cover artwork by Tomasz Ahrends.
|
MAC_Bench/Cell/Story/Caner Cell/27_3.txt
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vith
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27_3.txt
|
On the cover: In this issue of Cancer Cell, Sagnella et al. (pp. 354–370) show that nanocells attack tumors by delivering a
cytotoxin and engaging multiple arms of the immune system. The cytotoxin binds and
kills tumor cells. Dendritic cells and macrophages engulf dying tumor cells and display
tumor-associated antigens that are recognized by CD8+ T cells. Activated CD8+ T cells
home to the tumor, recognizing and killing live tumor cells and augmenting the anti-tumor
effect. The cover is an artistic rendition of the dual roles of the cyto-immunotherapeutic
nanocells. Design: Himanshu Brahmbhatt and Jennifer MacDiarmid. Image: Martin Hale,
Animated Biomedical Productions.
|
MAC_Bench/Cell/Story/Caner Cell/37_4.txt
|
vitg
|
37_4.txt
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test
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ACS Applied Bio Materials
|
2024_10
|
Which of the following options best describe the cover image?
|
MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2024_10.png
|
B
|
The cover art depicts the photoresponsive conjugated polymer materials for applications in cell imaging, photodynamic therapy of cancer, and bioelectronic devices in a combined platform. Functionalization of the donor−acceptor-type polymer with a specific cellular targeting unit leads to uptake into tumor cell for fluorescent imaging. The photoresponsive polymer material could sensitize the molecular oxygen to generate reactive oxygen species leading to tumor cell death, while polymer materials can be modified to electrolytes to build up bioelectronic devices used for improving biocatalysis (photolysis of water to oxygen) and photoelectric conversion.
|
MAC_Bench/ACS/Story/ACS Applied Bio Materials/2018_6.txt
|
vith
|
2018_6.txt
|
The image shows electrohydraulic discharge plasma disinfecting pathogens in a field of green cruciferous vegetables under a clear blue sky, symbolizing sustainable agriculture. Oxygen and nitrogen molecule icons around the plasma indicate RONS production, with a healthy sprouting cabbage seedling to signify seed growth promotion.
|
MAC_Bench/ACS/Story/ACS Applied Bio Materials/2024_10.txt
|
groundtruth
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2024_10.txt
|
Enhancing the fertilization efficiency is a key aspect to make agriculture more sustainable and cope with the future food demand. In this work, we propose a green synthetic pathway to incorporate plant macronutrients (N and K) into bone-like calcium phosphate nanoparticles. These multinutrient nanofertilizers provide a slow and gradual release of macronutrients (NPK), resulting in a more efficient fertilization process. Encouraging results on wheat plants represent a further step toward a new dawn for precision agriculture.
|
MAC_Bench/ACS/Story/ACS Applied Bio Materials/2020_10.txt
|
vitg
|
2020_10.txt
|
The cover image depicts the semiconducting oligomer amphiphiles (OPV-PEG)-based activatable nanoprobes for in vivo imaging of biothiols. OPV-PEG is composed of a hydrophobic semiconducting segment that serves as both the signal source and the sensing moiety for biothiols, and the hydrophilic poly(ethylene glycol) (PEG) side chains to provide the water-solubility. OPV-PEG can self-assemble with a near-infrared (NIR) photosensitizer to emit both NIR fluorescence and afterglow luminescence. In the presence of biothiols in living animals, the NIR fluorescence of this nanoprobe is turned on, but the afterglow signal remains the same, which permits precise tracking of the probe location while detecting biothiols.
|
MAC_Bench/ACS/Story/ACS Applied Bio Materials/2018_3.txt
|
clip
|
2018_3.txt
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val
|
Molecular Pharmaceutics
|
2024_6
|
Which of the following options best describe the cover image?
|
MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2024_6.png
|
D
|
The cover art symbolizes the importance of the prediction and control of the solid form in pharmaceutical solid state chemistry, a subject explored within this Virtual Special Issue (VSI) titled “Crystallizing the Role of Solid-State Form in Drug Delivery.” This VSI is jointly produced by Molecular Pharmaceutics and Crystal Growth & Design [https://pubs.acs.org/page/vi/solid-state-form-drug-delivery] and is guest edited by Dr. Doris Braun (University of Innsbruck), Prof. Lidia Tajber (Trinity College Dublin), Prof. Lynne Taylor (Purdue University), and Prof. Jonathan Steed (Durham University). The guest editors have selected a wide range of articles that collectively highlight ongoing advances in formulation approaches and our understanding of the molecular solid state. This new VSI builds on the joint retrospective Virtual Issue published in February 2021 [https://pubs.acs.org/page/cgdefu/vi/crystals-drug-delivery?ref=vi_collection]. A
|
MAC_Bench/ACS/Story/Molecular Pharmaceutics/2022_5.txt
|
vith
|
2022_5.txt
|
The cover art demonstrates the key finding from a study titled “Stabilizing Mechanisms of β-Lactoglobulin in Amorphous Solid Dispersions of Indomethacin”. β-Lactoglobulin-based amorphous solid dispersions of indomethacin are substantially stable even at 50–
|
MAC_Bench/ACS/Story/Molecular Pharmaceutics/2022_2.txt
|
clip
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2022_2.txt
|
Highlighting the cutting-edge, multidisciplinary, translational research in pharmaceutical sciences originating from researchers across Asia, the American Chemical Society journal Molecular Pharmaceutics is pleased to present a Virtual Special Issue titled "Advances in Molecular Pharmaceutical Research from Asia." Within the VSI, the Guest Editors have collected a wide range of articles that spotlights the wide range of research in the region. An accompanying editorial by the Guest Editor Team provides context and commentary to accompany the collection.
|
MAC_Bench/ACS/Story/Molecular Pharmaceutics/2023_5.txt
|
vitg
|
2023_5.txt
|
Point-of-care (POC) manufacturing facilities enable an agile pharmaceutical production paradigm that can respond to localized needs, providing personalized and precision medicine. We employed a theoretical framework encompassing the production of active pharmaceutical ingredient "inks" at a centralized facility, which are distributed to POC sites for DoD dispensing into/onto delivery vehicles (e.g., orodispersible films, capsules, and single liquid dose vials).
|
MAC_Bench/ACS/Story/Molecular Pharmaceutics/2024_6.txt
|
groundtruth
|
2024_6.txt
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test
|
BDJ
|
237_5
|
Which of the following options best describe the cover image?
|
MAC_Bench/Nature/Cover/BDJ/237_5.png
|
A
|
In this issue
This issue features articles on MRONJ, virtual clinics, and polishing systems.
Cover image: From 2019. The BDA Museum series which inspired the cover on this current issue was a direct lookback and comparison with modern practice and was published in the second half of 2019. One item was an operating face mask from the 1920s, complete with its stylish box (from Vol 227 Issue 8, 25 October 2019). As the series drew to a close at the end of that year, no one had any notion whatsoever of the pandemic that was about to engulf us in 2020 when the use of personal protective equipment became such a crucial element of enabling continuing health care.
©Tim Marrs
|
MAC_Bench/Nature/Story/BDJ/237_5.txt
|
groundtruth
|
237_5.txt
|
In this issue
This issue features articles on dentistry during the COVID-19 pandemic, the impact of COVID-19 on BAME dental professionals, and domestic violence during the pandemic.
Image credit: Joanna Culley
|
MAC_Bench/Nature/Story/BDJ/228_1.txt
|
clip
|
228_1.txt
|
In this issue
This issue features articles on experiences among volunteer dentists, integrated care, and diabetes and periodontitis.
Art ©Belmira Okoro, Image ©asbe/E+/Getty Images Plus
|
MAC_Bench/Nature/Story/BDJ/231_10.txt
|
ave_2
|
231_10.txt
|
In this issue
This issue features articles on dental fomite detection, endodontic complexity, and denture cleanliness and hygiene.
Cover image: This special cover series marks 150 years of the BDJ through visual storytelling. The illustrations ahead hope to encourage people to read the original papers, learn from our past and reflect on what we know now. Here the style, line, gesture and symbolism sets the scene for dental intervention within the Victorian classroom (graphite drawing).
Cover art by Rachel Jackson
|
MAC_Bench/Nature/Story/BDJ/233_12.txt
|
vitg
|
233_12.txt
|
val
|
Nature Climate Change
|
14_5
|
Which of the following options best describe the cover image?
|
MAC_Bench/Nature/Cover/Nature Climate Change/14_5.png
|
C
|
Coral rapid adaption
Due to anthropogenically driven thermal heat stress, tropical coral species, including Porites lichen as shown on the cover, are in decline. Their survival is therefore dependent on the ability to adapt or acclimatise. The prospects for rapid adaptive responses, including the role of transgenerational plasticity, are discussed in this Perspective.
See Nature Climate Change 7, 627-636
IMAGE: GERGELY TORDA
COVER DESIGN: LAUREN HESLOP
|
MAC_Bench/Nature/Story/Nature Climate Change/7_4.txt
|
clip
|
7_4.txt
|
Deoxygenation threatens reefs
Climate-change-associated ocean deoxygenation is a growing threat to marine ecosystems, including tropical coral reefs. In this issue, Pezner et al. use data from 32 coral reef habitats to demonstrate that hypoxic (low oxygen) conditions are already occurring on tropical coral reefs and that hypoxic event intensity, duration and severity will increase under continued ocean warming.
See Pezner et al.
Image: Yi Wei, National Sun Yat-sen University. Cover design: Valentina Monaco
|
MAC_Bench/Nature/Story/Nature Climate Change/13_9.txt
|
ave_2
|
13_9.txt
|
Debating coral futures
Coral reef bleaching is a common image of climate change impacts on marine ecosystems. In this month’s issue, we feature three opinion pieces discussing the future of coral reefs, including the need to move beyond narratives of global loss and considerations over the costs and benefits of choosing active intervention pathways.
See Streit et al., Webster et al. and McClanahan
Image: Marianne Purdie/Moment/Getty Images. Cover design: Debbie Maizels
|
MAC_Bench/Nature/Story/Nature Climate Change/14_5.txt
|
groundtruth
|
14_5.txt
|
The breadth and depth of ocean change
Climate change impacts on global oceans are varied, far-reaching and severe. In our Editorial we discuss work featured in this issue of Nature Climate Change, which ranges from the surface to the ocean depths, through physical changes and biological impacts, and encompasses scales from the sub-cellular to the global.
See Editorial.
Image: Olena Holubova / Alamy Stock Photo. Cover Design: Valentina Monaco
|
MAC_Bench/Nature/Story/Nature Climate Change/12_3.txt
|
ave_1
|
12_3.txt
|
train
|
One Earth
|
7_5
|
Which of the following options best describe the cover image?
|
MAC_Bench/Cell/Cover/One Earth/7_5.png
|
B
|
On the cover: The inaugural issue of One Earth focuses on climate action. Climate change is arguably the defining challenge of our
time, but more importantly, it is our inaction that will jeopardize the well-being
of future generations. Here, our cover depicts the generation at risk and their awareness
of, and engagement with, the climate issue while also reinterpreting the UN Sustainable
Development Goals' call for climate action icon (SDG 13).
|
MAC_Bench/Cell/Story/One Earth/1_4.txt
|
clip
|
1_4.txt
|
On the cover: Our cities are growing hotter. An urban heat island effect, augmented
by climate change, is creating stifling and dangerous conditions in urban centers,
and cooling solutions are at a premium. Air conditioning units, the go-to solution,
are expensive, energy hungry, and can release problematic refrigerants. Ballyscanlon,
Getty.
|
MAC_Bench/Cell/Story/One Earth/7_5.txt
|
groundtruth
|
7_5.txt
|
On the cover: Decarbonizing cities could hold the key to the successful reduction
of greenhouse gas emissions. However, cities are complex, multifaceted entities. A
systems approach is needed to help identify patterns among the chaos. Credit: Mikhail
Derevyanov/EyeEm via Getty Images.
|
MAC_Bench/Cell/Story/One Earth/5_6.txt
|
ave_2
|
5_6.txt
|
On the cover: Protecting the planet against further harm is critical, now more than
ever. To address the complex, interrelated, socio-environmental challenges threatening
societies and ecosystems, we need governance for sustainability. Image credit: Baac3nes
via Getty Images.
|
MAC_Bench/Cell/Story/One Earth/5_7.txt
|
ave_3
|
5_7.txt
|
val
|
NATURE REVIEWS GENETICS
|
26_2
|
Which of the following options best describe the cover image?
|
MAC_Bench/Nature/Cover/NATURE REVIEWS GENETICS/26_2.png
|
A
|
Inspired by the Review on p7.
Cover design: Patrick Morgan
|
MAC_Bench/Nature/Story/NATURE REVIEWS GENETICS/26_2.txt
|
groundtruth
|
26_2.txt
|
Inspired by the Review on p203
Cover design: Patrick Morgan.
|
MAC_Bench/Nature/Story/NATURE REVIEWS GENETICS/22_9.txt
|
clip
|
22_9.txt
|
Cover by Patrick Morgan. Original image sources: DNA - PhotoDisc/Getty; Stethoscope/keyboard - iStockphoto/Getty.
|
MAC_Bench/Nature/Story/NATURE REVIEWS GENETICS/19_12.txt
|
vitg
|
19_12.txt
|
Cover by Patrick Morgan. Inspired by the Perspective on p175.
|
MAC_Bench/Nature/Story/NATURE REVIEWS GENETICS/19_10.txt
|
vith
|
19_10.txt
|
train
|
ACS Food Science & Technology
|
2024_2
|
Which of the following options best describe the cover image?
|
MAC_Bench/ACS/Cover/ACS Food Science & Technology/2024_2.png
|
C
|
Factors contributing to honey botanical origin and volatile fingerprint: (1)
|
MAC_Bench/ACS/Story/ACS Food Science & Technology/2024_10.txt
|
clip
|
2024_10.txt
|
This study determined the efficacy of carotenes in modulating molecular targets in a hydrogen peroxide (H2O2)-induced AMD in vitro model. To evaluate cytotoxicity, a panel of 17 human cancer cells and non-cancerous human retinal pigment epithelium (ARPE-19) cells were treated with carotenes. A polymerase chain reaction (PCR) array study was conducted to evaluate the efficacy of carotenes in modulating oxidative stress, and its underlying molecular targets were also studied using bioinformatic analyses through reactome pathway analysis and targeted cell-based reporter assays.
|
MAC_Bench/ACS/Story/ACS Food Science & Technology/2022_2.txt
|
vitg
|
2022_2.txt
|
Optimizing brewing conditions to enhance probiotic viability in beer: Twenty-one lactic acid bacteria strains with potential probiotic properties were tested for resilience against ethanol and hops, with certain strains thriving in Gueuze-style sour beer. Findings indicate that alternative methods are required to support probiotic viability in hopped beers. This cover image was created using Canva AI.
|
MAC_Bench/ACS/Story/ACS Food Science & Technology/2024_2.txt
|
groundtruth
|
2024_2.txt
|
This research shows the high efficacy of wet ball milling for modifying rice starch structure and pasting behavior, which is insightful for designing cost-effective mechanical processes for rice starch-based foods.
|
MAC_Bench/ACS/Story/ACS Food Science & Technology/2021_8.txt
|
vith
|
2021_8.txt
|
test
|
Nature Biomedical Engineering
|
8_6
|
Which of the following options best describe the cover image?
|
MAC_Bench/Nature/Cover/Nature Biomedical Engineering/8_6.png
|
B
|
Engineering extracellular vesicles to target T cells
This issue highlights intestinal organoids for the analysis of off-tumour toxicities of T-cell-engaging bispecific antibodies, the affinity maturation of mouse B cells reprogrammed to express human antibodies, modular chimaeric cytokine receptors with leucine zippers, engineered extracellular vesicles for targeting T cells and for the delivery of mRNA to neurons, immune-privileged tissues formed from immunologically cloaked mouse embryonic stem cells, mesenchymal stromal cells with chimaeric antigen receptors, the generation of antigen-specific mature T cells from engineered stem cells, and engineered heart tissue for the study of metabolic rewiring during tachycardia.
The cover illustrates that extracellular vesicles can be engineered with multiple functionalities for the targeted delivery of biologics to T cells.
See Stranford et al.
Image: Justin Muir. Cover design: Alex Wing.
|
MAC_Bench/Nature/Story/Nature Biomedical Engineering/8_9.txt
|
ave_1
|
8_9.txt
|
Seeking antibiotics in the proteomes of extinct organisms
This issue highlights methods for spatial multi-omics at subcellular resolution, for the mapping of higher-order protein interactions, for studying the functions of non-coding regulatory elements, for interrogating sequence variation in antimicrobial peptides, for antimicrobial-peptide discovery by mining the proteome of extinct organisms, for reinforcing the intestinal mucosal barrier, and for the optogenetic stimulation of vagal nerves, to enhance glucose-stimulated insulin secretion.
The cover illustrates that compounds with antibiotic properties can be discovered by mining, using deep learning, the proteomes of all available extinct organisms.
See Wan et al.
Image: Pix Videos | de la Fuente Lab. Cover design: Alex Wing.
|
MAC_Bench/Nature/Story/Nature Biomedical Engineering/8_6.txt
|
groundtruth
|
8_6.txt
|
Supramolecular bispecific T cell engagers with controllable disassembly
This issue highlights advances in the design of bispecific T cell engagers, chimeric antigen receptor T cells, mineralized bacteria and other cellular as well as molecular immunotherapies for the modulation of the activity of the immune system against cancers and other inflammatory conditions.
The cover illustrates the small-molecule-mediated control of the antitumour activity of a supramolecular bispecific T cell engager through its disassembly.
See Gong et al.
Image: Ningqiang Gong. Cover design: Alex Wing.
|
MAC_Bench/Nature/Story/Nature Biomedical Engineering/8_8.txt
|
vith
|
8_8.txt
|
Patient-specific 3D-printed cardiac plugs
This issue highlights a personalized cardiovascular occluder made via 3D printing, a cloud-based machine-learning software for the prediction of CRISPR–Cas9 off-target effects, a stem-cell-based approach for the treatment of myocardial infarction, and engineered microbes for cancer chemoprevention.
The cover illustrates a 3D-printed personalized occluder for closing the heart’s left atrial appendage so as to prevent stroke in patients with atrial fibrillation.
See Robinson et al.
Image: Dalio Institute of Cardiovascular Imaging, Weill Cornell Medicine.
|
MAC_Bench/Nature/Story/Nature Biomedical Engineering/2_12.txt
|
clip
|
2_12.txt
|
val
|
Acta Pharmacologica Sinica
|
45_12
|
Which of the following options best describe the cover image?
|
MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/45_12.png
|
D
|
Cover Credit: CircNSD1 acts as ceRNA of miR-429-3p to promote the target gene SULF1 expression and activate Wnt/β-catenin pathway signaling to enhance fibroblasts proliferation and collagen deposition leading to cardiac fibrosis. (DOI 10.1038/s41401-024-01296-7). See the article in pages 2092-2106.
|
MAC_Bench/Nature/Story/Acta Pharmacologica Sinica/45_3.txt
|
clip
|
45_3.txt
|
Cover Credit: Mechanisms of Takeda G protein-coupled receptor-5 (TGR5) agonist on inhibiting intestinal epithelial cell apoptosis and ameliorating ulcerative colitis. Activation of TGR5 by OM8 enhanced cAMP/PKA signaling, which led to upregulation of c-FLIP expression, and subsequently suppressed JNK phosphorylation, thereby antagonizing TNF-α induced intestinal epithelial cell apoptosis.
|
MAC_Bench/Nature/Story/Acta Pharmacologica Sinica/44_5.txt
|
vitg
|
44_5.txt
|
Cover Credit: Urolithin A, as a fruit-derived natural product, protects against atherosclerotic plaque vulnerability by pleiotropic mechanisms, including promoting NO production, inhibiting YAP/TAZ-dependent endothelial inflammation as well as lowering lipid levels. Doi:10.1038/s41401-024-01317-5. See the article in pages 2277–2289
|
MAC_Bench/Nature/Story/Acta Pharmacologica Sinica/45_2.txt
|
ave_1
|
45_2.txt
|
Cover Credit: DZ2002, a reversible inhibitor of type III S-adenosyl-L-homocysteine hydrolase, attenuates TNF-α-induced NF-κB signaling by suppressing the degradation and phosphorylation of IκB, along with NF-κB p65 phosphorylation and nuclear translocation. Additionally, DZ2002 inhibits the activation of molecules in the STAT3-PI3K-Akt pathway, suppressing the secretion of inflammatory cytokines and pro-angiogenic factors. These findings strongly support DZ2002's promising therapeutic potential for dry eye disease (DED).
|
MAC_Bench/Nature/Story/Acta Pharmacologica Sinica/45_12.txt
|
groundtruth
|
45_12.txt
|
train
|
ACS ES&T Air
|
2024_8
|
Which of the following options best describe the cover image?
|
MAC_Bench/ACS/Cover/ACS ES&T Air/2024_8.png
|
D
|
This study illustrates the molecular composition of organic aerosols collected in the Houston, Texas region using direct sampling interfaced with high-resolution mass spectrometry. This study highlights the episodic prevalence and day/nighttime distribution of organosulfates and organonitrates enriched species.
|
MAC_Bench/ACS/Story/ACS ES&T Air/2024_3.txt
|
clip
|
2024_3.txt
|
Ethylene oxide (EtO) is a colorless, flammable, reactive gas commonly used for sterilization and chemical manufacturing that has become a contaminant of concern for the U.S. EPA as a result of an assessment of its toxicity, which found that EtO is more potent than had been previously understood.
|
MAC_Bench/ACS/Story/ACS ES&T Air/2024_5.txt
|
ave_3
|
2024_5.txt
|
Computational models of atmospheric composition do not always make scientifically trustworthy predictions. This is especially true for machine learning and AI tools that learn patterns from data without knowing the physical laws governing those patterns. We introduce a corrective approach that minimally adjusts the predicted concentrations of chemical species to guarantee conservation of mass.
|
MAC_Bench/ACS/Story/ACS ES&T Air/2025_2.txt
|
ave_2
|
2025_2.txt
|
Decamethylcyclopentasiloxane (D5) in personal care products vaporizes and undergoes oxidation in the atmosphere in the presence of hydroxyl radicals, resulting in the formation of oxidized compounds that contribute to aerosol formation. Such oxidation products were identified in fine particulate matter collected from the urban atmosphere of New York City. The background of this image was created by DALL·E3.
|
MAC_Bench/ACS/Story/ACS ES&T Air/2024_8.txt
|
groundtruth
|
2024_8.txt
|
train
|
NATURE BIOTECHNOLOGY
|
42_6
|
Which of the following options best describe the cover image?
|
MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/42_6.png
|
B
|
Nature Biotechnology celebrates 15 years of publishing the very best of biotech science and business. Cover art: Marina Corral.
|
MAC_Bench/Nature/Story/NATURE BIOTECHNOLOGY/29_10.txt
|
vith
|
29_10.txt
|
Measuring organellar sodium ions
A DNA nanodevice measuring organellar sodium ion levels in lysosomes of living cells. Zou et al. developed RatiNa for imaging intracellular Na+ at single-organelle resolution.
See Zou et al.
Image: Junyi Zou and Bruna Di Giacomo. Cover design: Erin Dewalt
|
MAC_Bench/Nature/Story/NATURE BIOTECHNOLOGY/42_6.txt
|
groundtruth
|
42_6.txt
|
Nature Biotechnology celebrates its 20-year anniversary. Cover art: Erin Boyle
|
MAC_Bench/Nature/Story/NATURE BIOTECHNOLOGY/34_10.txt
|
clip
|
34_10.txt
|
Nature Biotechnology celebrates its 25th anniversary
Nature Biotechnology celebrates 25 years of publishing the very best of biotech science and business.
See Editorial
Image: Peter Crowther. Cover Design: Erin Dewalt.
|
MAC_Bench/Nature/Story/NATURE BIOTECHNOLOGY/39_10.txt
|
ave_2
|
39_10.txt
|
train
|
NATURE IMMUNOLOGY
|
25_8
|
Which of the following options best describe the cover image?
|
MAC_Bench/Nature/Cover/NATURE IMMUNOLOGY/25_8.png
|
C
|
Formation of memory precursor NK cells
Natural killer (NK) cells are innate lymphocytes that possess traits of adaptive immunity, such as memory formation. O’Sullivan and colleagues show that the transcription factor Fli1 has important roles in controlling the establishment of NK cell memory.
See O’Sullivan
Image Credit: Helena Pinheiro. Cover design: Amie Fernandez
|
MAC_Bench/Nature/Story/NATURE IMMUNOLOGY/23_9.txt
|
vitg
|
23_9.txt
|
20 years of Nature Immunology
Twenty antibodies to reflect 20 years of Nature Immunology. To celebrate our anniversary, we have commissioned a series of Comments from some of our authors from the last 20 years that describe their landmark studies and how they drove immunology research forward.
See https://www.nature.com/collections/fddiddjdcj
Cover Design: Erin Dewalt.
|
MAC_Bench/Nature/Story/NATURE IMMUNOLOGY/21_6.txt
|
clip
|
21_6.txt
|
Regulating NK cell effector function
Li et al. identify the transcription factor MEF2C as essential for human natural killer (NK) cell function and viral immunity in mice and humans. This control is exerted by regulation of lipid metabolism, and deficiency in MEF2C can be overcome by supplementation with oleic acid.
See Li et al.
Image credit: Adalia Zhou, UCLA. Cover design: Amie Fernandez
|
MAC_Bench/Nature/Story/NATURE IMMUNOLOGY/25_8.txt
|
groundtruth
|
25_8.txt
|
NF-κB is the key transcription factor that orchestrates inflammatory responses and contributes to the development of the immune system. This month's focus features a series of specially commissioned review articles to mark the 25th anniversary of the discovery of NF-κB. http://www.nature.com/ni/focus/NF-kB/index.html Artwork by Lewis Long.
|
MAC_Bench/Nature/Story/NATURE IMMUNOLOGY/12_5.txt
|
ave_0
|
12_5.txt
|
val
|
Nature Sustainability
|
7_3
|
Which of the following options best describe the cover image?
|
MAC_Bench/Nature/Cover/Nature Sustainability/7_3.png
|
A
|
Ancient soil enrichment
Amazonian dark earth, rich soil resulting from ancient human land modification, has the potential to store substantial amounts of carbon, yet the number and size of Amazonian dark earth sites is unknown. Goldberg and colleagues develop a remote-sensing approach leveraging machine-learning classifiers to reveal its present extent.
See Goldberg et al.
Image: Bruno Moraes Puente Institute, (Nederland, CO, USA) and the Amazon Hopes Collective. Cover design: Alex Whitworth
|
MAC_Bench/Nature/Story/Nature Sustainability/7_3.txt
|
groundtruth
|
7_3.txt
|
Tropical forest carbon loss
Tropical forests store huge reserves of carbon but are under growing assault. Using satellite data, Zeng and colleagues show that annual carbon loss in tropical forests more than doubled between 2001 and 2019. Agricultural activities are driving most of this loss.
See Feng et al.
Image: LeoFFreitas / Moment / Getty. Cover Design: Valentina Monaco.
|
MAC_Bench/Nature/Story/Nature Sustainability/5_8.txt
|
clip
|
5_8.txt
|
Potential of uncontested lands
Restoring degraded landscapes for conservation purposes can involve transaction costs to acquire the land in the first place. McDonald-Madden and colleagues propose a framework for prioritizing uncontested lands that can provide ecosystem services without those costs.
See McDonald-Madden et al.
Image: Asa Rodger/Unsplash. Cover Design: David Shand.
|
MAC_Bench/Nature/Story/Nature Sustainability/3_12.txt
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ave_2
|
3_12.txt
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Forest subsidies in Chile
Given the benefits of forests, there are growing efforts to restore lost ones. This study finds that between 1986 and 2011, Chile’s forest subsidies encouraged expansion of plantations with exotic trees at the expense of native forest, likely reducing biodiversity and not increasing aboveground carbon storage.
See Heilmayr et al.
Image: Robert Heilmayr, University of California, Santa Barbara. Cover design: Valentina Monaco
|
MAC_Bench/Nature/Story/Nature Sustainability/3_4.txt
|
vith
|
3_4.txt
|
train
|
Cell Systems
|
15_6
|
Which of the following options best describe the cover image?
|
MAC_Bench/Cell/Cover/Cell Systems/15_6.png
|
B
|
On the cover: Cells occupy a diverse range of single cell states. In this issue of
Cell Systems, a team from the Allen Institute for Cell Science (Gerbin et al., 670–687) classified
thousands of single cells to quantify the relationship between cell organization and
gene expression. Here, the diversity of cell organization and gene expression is shown
in hiPSC-derived cardiomyocytes, where the sarcomere is labeled with alpha-actinin-2-mEGFP
(white). Cells are colored by the combined organizational score. Image credit: Thao
Do and the authors.
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MAC_Bench/Cell/Story/Cell Systems/12_7.txt
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ave_1
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12_7.txt
|
On the cover: An array of human kidney organoids patterned with precise control over
starting nephron progenitor number. Staining for podocytes (NPHS1, yellow), proximal
tubules (LTL, cyan), and distal tubules (ECAD, bright pink) demonstrates the capability
for more targeted self-organization of organoid tissues and structures. In this issue
of Cell Systems, Porter et al. use a DNA-based cell patterning technology to demonstrate that precise control over
the initial numbers and ratios of epithelial progenitors modulates tissue composition
and morphology in a human kidney organoid model. Image credit: the authors.
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MAC_Bench/Cell/Story/Cell Systems/15_6.txt
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groundtruth
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15_6.txt
|
On the cover: Cell Systems turns one. This issue features a Focus on RECOMB (Li et al., 21–34; Sefer et al.,
35–42; El-Kebir et al., 43–53; Simmons et al., 54–61; Dao et al., 62–70) and our new
Tool article format (Durand et al., 95–98 and 99–101; Liepe et al., 102–107) and badge
(Ritchie et al., 71–82). They represent one aspect of our broader ambition to bridge
research fields (see our Editorial, 1–2), including between experimental and computational
biologists (see Voices, 7–11). Scan the QR code for a special anniversary message
from the editors.
|
MAC_Bench/Cell/Story/Cell Systems/3_6.txt
|
clip
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3_6.txt
|
On the cover: What if each cell contained its own “experimentalist,” determining whether
to turn on GFP expression depending on the particular signaling dynamics it encountered?
In this issue of Cell Systems, Pavithran Ravindran, Jared Toettcher, and colleagues develop and validate synthetic
gene circuits, based on an incoherent feed-forward loop architecture, that selectively
respond to pulses of signaling activity. This opens the door for uncovering both the
underpinnings and implications of signaling dynamics. Image created by Oliver Hoeller
(www.oliverhoeller.com).
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MAC_Bench/Cell/Story/Cell Systems/13_11.txt
|
ave_2
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13_11.txt
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train
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Nature Reviews Neurology
|
20_12
|
Which of the following options best describe the cover image?
|
MAC_Bench/Nature/Cover/Nature Reviews Neurology/20_12.png
|
B
|
HIV and the brain, inspired by the Consensus Statement on p424.
Cover design: P.Patenall
|
MAC_Bench/Nature/Story/Nature Reviews Neurology/19_6.txt
|
clip
|
19_6.txt
|
Overlapping phenotypes, inspired by the Review on p7.
Cover design: Philip Patenall
|
MAC_Bench/Nature/Story/Nature Reviews Neurology/20_12.txt
|
groundtruth
|
20_12.txt
|
A global view of Alzheimer disease genetics, inspired by the Review on p261
Cover design: Philip Patenall
|
MAC_Bench/Nature/Story/Nature Reviews Neurology/19_8.txt
|
ave_1
|
19_8.txt
|
Genetics of cerebral small vessel disease, inspired by the Review on p84.
Cover design: Philip Patenall.
|
MAC_Bench/Nature/Story/Nature Reviews Neurology/18_11.txt
|
vith
|
18_11.txt
|
train
|
BDJ
|
237_12
|
Which of the following options best describe the cover image?
|
MAC_Bench/Nature/Cover/BDJ/237_12.png
|
D
|
In this issue
This issue features articles on MRONJ, virtual clinics, and polishing systems.
Cover image: From 2019. The BDA Museum series which inspired the cover on this current issue was a direct lookback and comparison with modern practice and was published in the second half of 2019. One item was an operating face mask from the 1920s, complete with its stylish box (from Vol 227 Issue 8, 25 October 2019). As the series drew to a close at the end of that year, no one had any notion whatsoever of the pandemic that was about to engulf us in 2020 when the use of personal protective equipment became such a crucial element of enabling continuing health care.
©Tim Marrs
|
MAC_Bench/Nature/Story/BDJ/237_5.txt
|
vitg
|
237_5.txt
|
In this issue
This issue features articles on dental fomite detection, endodontic complexity, and denture cleanliness and hygiene.
Cover image: This special cover series marks 150 years of the BDJ through visual storytelling. The illustrations ahead hope to encourage people to read the original papers, learn from our past and reflect on what we know now. Here the style, line, gesture and symbolism sets the scene for dental intervention within the Victorian classroom (graphite drawing).
Cover art by Rachel Jackson
|
MAC_Bench/Nature/Story/BDJ/233_12.txt
|
vith
|
233_12.txt
|
In this issue
This issue features articles on experiences among volunteer dentists, integrated care, and diabetes and periodontitis.
Art ©Belmira Okoro, Image ©asbe/E+/Getty Images Plus
|
MAC_Bench/Nature/Story/BDJ/231_10.txt
|
clip
|
231_10.txt
|
In this issue
This issue features articles on dental anxiety, cardiothoracic surgery, and the very first of our new “Review” article type!
Cover image: From 2005. A dentist painting her view from the practice ‘window on the world’, inspired by the selected cover image as an artwork hanging on the surgery wall (original cover by Irfan Ahmad, taken from Vol 199 Issue 4, 27 August 2005). See ‘Behind the new cover series’ written by Stephen in the News and Views section for further explanation.
©Tim Marrs, incorporating original cover art by Irfan Ahmad
|
MAC_Bench/Nature/Story/BDJ/237_12.txt
|
groundtruth
|
237_12.txt
|
train
|
Nature Reviews Neurology
|
20_3
|
Which of the following options best describe the cover image?
|
MAC_Bench/Nature/Cover/Nature Reviews Neurology/20_3.png
|
C
|
Modelling Alzheimer disease in a dish, inspired by the Review on p25.
Cover design: Philip Patenall.
|
MAC_Bench/Nature/Story/Nature Reviews Neurology/18_12.txt
|
clip
|
18_12.txt
|
Mechanism-based drug development in neuromyelitis optica spectrum disorders, inspired by the Review on p759.
Cover design: Philip Patenall.
|
MAC_Bench/Nature/Story/Nature Reviews Neurology/17_1.txt
|
vith
|
17_1.txt
|
Spectrum of disease, inspired by the Review on p602.
Cover design: Amie Fernandez
|
MAC_Bench/Nature/Story/Nature Reviews Neurology/20_3.txt
|
groundtruth
|
20_3.txt
|
Single-cell technologies and brain disease, inspired by the Review on p346.
Cover design: Philip Patenall
|
MAC_Bench/Nature/Story/Nature Reviews Neurology/19_7.txt
|
vitg
|
19_7.txt
|
val
|
Science Robotics
|
9_92
|
Which of the following options best describe the cover image?
|
MAC_Bench/Science/Cover/Science Robotics/9_92.png
|
D
|
ONLINE COVER Drones branch out. Continuous and systematic biomonitoring of natural environments could enable a better understanding of how the biosphere responds to environmental changes. Environmental DNA (eDNA) is a useful tool for assessing biodiversity levels, particularly in forests. Aucone et al. report a drone that can autonomously land and sample eDNA on tree branches with different stiffnesses. This month's cover is a photograph of the drone resting on a branch. Credit: Gottardo Pestalozzi and Enrico Pestalozzi
|
MAC_Bench/Science/Story/Science Robotics/8_74.txt
|
ave_2
|
8_74.txt
|
ONLINE COVER Special Issue on Autonomy and AI in Robotics. A team of legged robots can efficiently explore unstructured terrains with task-level autonomy. Arm et al. report on a robot team comprising a “scout” that can identify potential scientific targets in an environment, a “hybrid” that collects data from the targets, and a “scientist” that performs in-depth scientific analysis of the targets. The robot team could efficiently map terrain mimicking planetary environments, identify resource-enriched areas, and scientifically analyze targets of interest. This month’s cover is an image of a team of legged robots exploring a field of boulders. Credit: Arm et alMAC_Bench/Science Robotics
|
MAC_Bench/Science/Story/Science Robotics/8_80.txt
|
clip
|
8_80.txt
|
ONLINE COVER Special Issue on Robots in the Wild. Robots have been successfully deployed in a wide range of domains–including land, sea, air, and space–for a variety of applications such as search and rescue, oceanography, wildlife surveys, and space exploration. In this issue, Zhou et al. have developed a trajectory planner for swarms of micro drones that can be implemented using only an onboard computer. Their planner computes trajectories based on limited information from the drone's onboard sensors to enable collision-free flight in cluttered environments in the wild. This month's cover is a photo illustration of a swarm of micro-drones flying through a forest (see also the Focus by Soria). Credit: Zhou et al./Zhejiang University
|
MAC_Bench/Science/Story/Science Robotics/7_66.txt
|
vitg
|
7_66.txt
|
ONLINE COVER Robot Visual Trajectory Following. A bioinspired vision-based approach can enable small autonomous drones to follow routes over long distances. Van Dijk et al. developed a strategy for robot trajectory following that is inspired by desert ants to enable small drones to navigate without the need for high computational demands. The strategy combines odometry with highly compressed visual snapshots to record outbound flights with minimal memory consumption. Visual homing was then used on inbound flights to minimize the potential of drifting off course in autonomous drone navigation. This month’s cover shows a lightweight drone capable of visual route following to navigate in a forested environment. Credit: TU Delft, photo by Studio Oostrum
|
MAC_Bench/Science/Story/Science Robotics/9_92.txt
|
groundtruth
|
9_92.txt
|
val
|
Cell Metabolism
|
36_10
|
Which of the following options best describe the cover image?
|
MAC_Bench/Cell/Cover/Cell Metabolism/36_10.png
|
A
|
On the cover: Stress has a profound impact on gut disorders. In this issue of Cell Metabolism, Wei et al. reveal that psychological stress enriches gut microbial metabolite indole-3-acetate,
which disrupts intestinal stem cell differentiation and triggers epithelial injury.
The depiction of rolling clouds and stirring stars, inspired by Van Gogh’s masterpiece
The Starry Night, represents restless emotions in a person with depression. The broken ground and
castle along the winding river illustrate injured intestinal epithelia. The involvement
of microbes and the metabolite is represented as ants on the broken door. Cover art
by Xiao Zheng and Haiping Hao.
|
MAC_Bench/Cell/Story/Cell Metabolism/36_10.txt
|
groundtruth
|
36_10.txt
|
On the cover: The current issue marks the 15th anniversary of Cell Metabolism. To highlight the occasion, original artwork was commissioned from the artist Michael
Pantuso (https://www.pantusodesign.com/) and shared with the journal. The image reflects the exploration, typically in mouse
models, and reporting of strong mechanistic insight into physiology and disease that
have been the hallmark of research reports in Cell Metabolism since its inception.
|
MAC_Bench/Cell/Story/Cell Metabolism/31_6.txt
|
clip
|
31_6.txt
|
On the cover: This month we are celebrating Cell’s 50th anniversary by focusing on the exciting metabolic research that Cell Press
publishes across its titles. This month’s covers of Cell Metabolism, Cell, and Trends in Endocrinology & Metabolism, when put side-by-side, form a single image, reflective of the variety of topics
on metabolic research that you will find across the three journals and the connections
between them. Our cover reflects some of the contents of this issue, spanning from
review articles covering human cardiac metabolism (Bornstein et al.) and metabolic reprogramming in liver fibrosis (Horn and Tacke) to clinical studies on using thermal face imaging to predict aging and disease (Yu, Zhou, Mao et al.). Artwork credit: Sonhita Chakraborty.
|
MAC_Bench/Cell/Story/Cell Metabolism/36_6.txt
|
vitg
|
36_6.txt
|
On the cover: Although metabolism and apoptosis are critical for cellular homeostasis,
the connectivity between the two processes is unclear. On pp. 1217–1231, Lin et al.
use CRISPR/Cas9 loss-of-function screens to identify metabolic genes capable of influencing
cellular commitment to apoptosis. This analysis reveals metabolic pathways that specifically
cooperate with BCL-2 to sustain survival and maps out new potential targets for chemotherapy
in tumor cells. The cover image uses a cartographic metaphor to illustrate the concept
of a metabolic-apoptotic interface (represented by the vertical mountain range) being
actively mapped by a “CRISPR” pencil. Artwork by Leah Bury.
|
MAC_Bench/Cell/Story/Cell Metabolism/29_2.txt
|
ave_2
|
29_2.txt
|
val
|
ACS Engineering Au
|
2024_1
|
Which of the following options best describe the cover image?
|
MAC_Bench/ACS/Cover/ACS Engineering Au/2024_1.png
|
B
|
Frontier orbital energies of small organic molecules can be represented using knowledge-based and struct
|
MAC_Bench/ACS/Story/ACS Engineering Au/2022_3.txt
|
clip
|
2022_3.txt
|
This work presents the sustainable green solvent engineering for the synthesis of REWO (RE = Ce, Sm, Gd) nanoparticles, which are modified disposable screenprinted carbon electrodes for the electrochemical detection of 4-nitrotoluene in real-time analysis of water samples.
|
MAC_Bench/ACS/Story/ACS Engineering Au/2024_1.txt
|
groundtruth
|
2024_1.txt
|
Ammonia selective catalytic reduction (NH3-SCR) has been extensively applied for NOx emission control, where the formation of the greenhouse gas N2O is an issue.
|
MAC_Bench/ACS/Story/ACS Engineering Au/2024_3.txt
|
ave_2
|
2024_3.txt
|
Selective catalysts for the Oxidative Coupling of Methane (OCM) exhibit low ethane and ethylene (C2) productivity due to their limited activity. More active catalysts, on the other hand, often suffer from a low selectivity, resulting in pronounced carbon oxide formation. In this work, we try to combine the best of both worlds in adiabatic layered packed-bed reactors, with an active catalyst upstream of a more selective one, as an optimal solution to enhance the C2 productivity in the OCM process.
|
MAC_Bench/ACS/Story/ACS Engineering Au/2021_2.txt
|
vitg
|
2021_2.txt
|
train
|
Journal of the American Chemical Society
|
2024_47
|
Which of the following options best describe the cover image?
|
MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2024_47.png
|
D
|
A liquid–solid hybrid catalyst derived from Pickering emulsions has been successfully developed for continuous-flow reactions, which provides a new way for bridging the conceptual and technical gaps between homogeneous, heterogeneous and biological catalysis. See Yang and co-workers, DOI: 10.1021/jacs.8b11860. View the article.
|
MAC_Bench/ACS/Story/Journal of the American Chemical Society/2019_39.txt
|
vitg
|
2019_39.txt
|
This cover shows electrochemical gating of the molecular conductance of a redox-active osmium-containing molecular bridge, which is attached to the gold surface by direct gold—carbon bonding. Electrochemically gated electron transfer in an STM nanogap configuration is achieved for this metal—carbon contacted molecule. See Calvo and co-workers, p 2494. View the article.
|
MAC_Bench/ACS/Story/Journal of the American Chemical Society/2010_44.txt
|
clip
|
2010_44.txt
|
The cover represents an artistic view of the dynamic equilibrium in which conjugated porphyrin dimers (endowed with suitable crown ethers) associate with two fullerene-based guest molecules (bearing ammonium salts) by means of supramolecular forces involving complementary ammonium-crown ether interactions and π−π interactions between the porphyrin rings and the C60 moieties.
|
MAC_Bench/ACS/Story/Journal of the American Chemical Society/2016_5.txt
|
vith
|
2016_5.txt
|
LiFePO4–Li
|
MAC_Bench/ACS/Story/Journal of the American Chemical Society/2024_47.txt
|
groundtruth
|
2024_47.txt
|
train
|
NATURE REVIEWS CANCER
|
24_12
|
Which of the following options best describe the cover image?
|
MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/24_12.png
|
D
|
Aquatic diversity, inspired by the Reviews on p485 and p516.
Cover design: Lara Crow
|
MAC_Bench/Nature/Story/NATURE REVIEWS CANCER/20_4.txt
|
vith
|
20_4.txt
|
‘Empowering women in science; time for change?’, inspired by the Viewpoint on p547
Cover design: Lara Crow.
|
MAC_Bench/Nature/Story/NATURE REVIEWS CANCER/19_3.txt
|
ave_1
|
19_3.txt
|
Reflecting on 20 years, inspired by this month’s issue.
Cover design: Lara Crow.
|
MAC_Bench/Nature/Story/NATURE REVIEWS CANCER/21_3.txt
|
clip
|
21_3.txt
|
Chemotactic sirens, inspired by the Review on p28.
Cover design: Lara Crow
|
MAC_Bench/Nature/Story/NATURE REVIEWS CANCER/24_12.txt
|
groundtruth
|
24_12.txt
|
train
|
Nature Aging
|
4_10
|
Which of the following options best describe the cover image?
|
MAC_Bench/Nature/Cover/Nature Aging/4_10.png
|
A
|
Plasma membrane damage induces senescence
In this issue, Kojiro Suda, Yohsuke Moriyama, Nurhanani Razali and colleagues set out, using a genome-wide screen and gene-expression analysis in budding yeast, to better understand the cellular response to plasma membrane damage. The team discover that damage to the plasma membrane can limit replicative lifespan in yeast and induce senescence in human fibroblasts. The cover image shows kintsugi, the traditional Japanese art of repairing broken pottery by mending the cracks with urushi and gold. Kintsugi visibly incorporates the history of an object into its new form and thus transforms it. In this analogy, cell membrane damaged is repaired; however, rather than restoring the cell to its previous form, the new cellular nature is irreversibly changed and distinct from its previous state.
See Suda et al.
Image: Amy Cao. Cover design: Lauren Heslop.
|
MAC_Bench/Nature/Story/Nature Aging/4_10.txt
|
groundtruth
|
4_10.txt
|
Immune landscape in aging and frailty
In this issue, a study by Luo et al. reports blood immune cell profiles of newborn babies, young adults, and old adults with or without frailty syndrome. Combining cell-surface protein antibody-barcoded sequencing with single-cell RNA and T cell receptor sequencing, the study reveals characteristics of immune cells in healthy old age and frailty. The issue cover features a drawing of people at different stages of life, from infancy to old age.
See Luo et. al and the accompanying News & Views by De Maeyer and Akbar
Cover Image: Wen Lei, Jinan University. Cover Design: Lauren Heslop
|
MAC_Bench/Nature/Story/Nature Aging/2_9.txt
|
vith
|
2_9.txt
|
Inferring health trajectories
In this issue, Netta Mendelson Cohen et al. investigate individuals’ trajectories of healthy aging and age-related diseases. The researchers stitch together electronic health records with partial longitudinal coverage, using machine learning to untangle future healthy aging from chronic disease, and identify early indicators for healthy longevity. The cover image shows the study’s longevity-model features superimposed with representations of electronic health record information, which are connected via multiple solid or dotted lines that indicate differing propensities to drive the outputs of the models.
See Cohen et al.
Image: adapted from Nat. Aging https://doi.org/10.1038/s43587-023-00536-5 (2024), Springer Nature America (background and central graph), elenabs/iStock/Getty Images Plus (remaining elements). Cover Design: Lauren Heslop
|
MAC_Bench/Nature/Story/Nature Aging/4_12.txt
|
clip
|
4_12.txt
|
Cellular and proteomic profiling of aging and COVID-19
In this issue, a new Resource article from the Artyomov group documents and compares the human peripheral immune cell subset and plasma proteome characteristics of normal aging, moderate and severe COVID-19 disease, and non-COVID-19 lung diseases. The cover design features paper artwork depicting human lungs infected with SARS-CoV-2 and a variety of blood cell types as profiled in this study.
See Arthur et al. and the accompanying News and Views by Montgomery et al.
Image: Eugene Mymrin / Moment / Getty. Cover design: Lauren Heslop.
|
MAC_Bench/Nature/Story/Nature Aging/1_7.txt
|
vitg
|
1_7.txt
|
train
|
Journal of Chemical Theory and Computation
|
2025_1
|
Which of the following options best describe the cover image?
|
MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2025_1.png
|
B
|
A computational strategy is presented to improve the accuracy of local coupled cluster methods for systems containing first row transition metals. Dynamic correlation-induced orbital relaxation effects were identified as the main error source in local coupled cluster calculations. The cover art features a transition metal complex in the benchmark set.
|
MAC_Bench/ACS/Story/Journal of Chemical Theory and Computation/2023_18.txt
|
vitg
|
2023_18.txt
|
s-molecular dynamics simulations and umbrella sampling simulations allow the rationalization of New Delhi metallo-β-lactamase 1 enzyme inhibition by ebselen and ebsulfur to contrast antibiotic resistance. The role of chalcogen
|
MAC_Bench/ACS/Story/Journal of Chemical Theory and Computation/2025_1.txt
|
groundtruth
|
2025_1.txt
|
We have studied the reaction mechanism of the retaining glycosyltransferase ppGalNAcT2 using a combination of computational methods. The cover image shows the free energy surface calculated using metadynamics and a minimum free energy reaction path optimized using the string method. Both approaches yield a highly similar description of the reaction. The reaction proceeds from the reactant state (UDP-GalNAc + Thr; left) to the product state UDP + Thr-GalNAc; right) over a single barrier (transition state structure on top).
|
MAC_Bench/ACS/Story/Journal of Chemical Theory and Computation/2016_1.txt
|
ave_2
|
2016_1.txt
|
The effects of protein scaffolding on enzymatic catalysis are evident in the active site electron charge density. Geometric constraints on charge density isosurfaces mean that charge redistribution is facilitated in some regions and hindered in others. The most mobile regions of charge density coincide with bond bundles, which provide a sensitive probe for charge density analysis. The cover shows analogous bond bundles and critical point characteristic angles (double cones) in acetone and in the ketosteroid isomerase active side.
|
MAC_Bench/ACS/Story/Journal of Chemical Theory and Computation/2023_22.txt
|
clip
|
2023_22.txt
|
train
|
Caner Cell
|
42_6
|
Which of the following options best describe the cover image?
|
MAC_Bench/Cell/Cover/Caner Cell/42_6.png
|
D
|
On the cover: As Cancer Cell celebrates 10 years of publishing groundbreaking cancer
research, we reflect on the dramatic progress that has been made. The previous decade
has witnessed leaps forward in the understanding of the genetic, epigenetic, and metabolic
alterations in cancer cells, tumor heterogeneity, and the importance of the host in
tumor progression and therapy response. Experimental approaches such as RNA interference,
animal models, DNA sequencing, “omics,” and rational drug design have advanced tremendously
and greatly facilitated discovery. Several exciting new cancer therapeutics were approved
in the last decade. Encouraged by the achievements of the past decade, we look ahead
with excitement to the next 10 years of progress. Cover image by Scott Armstrong and
Eric D. Smith.
|
MAC_Bench/Cell/Story/Caner Cell/21_4.txt
|
vith
|
21_4.txt
|
On the cover: After one of the most challenging years marked by the COVID-19 pandemic
and a call for social change to eliminate racism and increase diversity and equity
in science, we want to bring hope for 2021. This issue of Cancer Cell features a Voices
(pp. 1–2) discussing lessons learned in 2020 and upcoming changes in cancer research
and oncology to shine some light on the future ahead.
|
MAC_Bench/Cell/Story/Caner Cell/39_12.txt
|
vitg
|
39_12.txt
|
On the cover: With the festive red and gold theme of this cover, the Cancer Cell editorial team celebrates the new year and kicks off the celebration of Cancer Cell’s 20th anniversary, which will span 2022 with many exciting articles.
|
MAC_Bench/Cell/Story/Caner Cell/40_12.txt
|
clip
|
40_12.txt
|
On the cover: Casanova-Salas et al. demonstrate how the genomic and transcriptomic cargo within circulating extracellular
vesicles (EVs) from liquid biopsies provides valuable insights into metastatic prostate
cancer outcomes and treatment responses and how this information could facilitate
the identification of biomarkers for guiding therapy switch decisions. The cover artwork
features an EV-lit traffic light, symbolizing the important role that circulating
EVs could play in the trafficking of clinically actionable information. Image credit:
Carlos Córdoba Terreros.
|
MAC_Bench/Cell/Story/Caner Cell/42_6.txt
|
groundtruth
|
42_6.txt
|
train
|
NATURE MATERIALS
|
23_3
|
Which of the following options best describe the cover image?
|
MAC_Bench/Nature/Cover/NATURE MATERIALS/23_3.png
|
D
|
Networks of notches in nanocomposite sheets prevent unpredictable local failure and increase the ultimate strain of the sheets from 4% to 370% without affecting their electrical conductance.
Letter p785
IMAGE: MATTHEW SHLIAN
COVER DESIGN: DAVID SHAND
|
MAC_Bench/Nature/Story/NATURE MATERIALS/14_5.txt
|
vitg
|
14_5.txt
|
Heteroepitaxial growth using aligned crystalline substrates allows extended metalorganic framework crystal growth oriented relative to the substrate.
Article p342; News & Views p283
IMAGE: KENJI OKADA, KEN IKIGAKI, MASAHIDE TAKAHASHI AND PAOLO FALCARO
COVER DESIGN: TULSI VORALIA
|
MAC_Bench/Nature/Story/NATURE MATERIALS/16_10.txt
|
clip
|
16_10.txt
|
2D material-wrapped Janus particles
Autoperforation of 2D materials for generating two-terminal memresistive Janus particles.
See Liu et al. and News & Views by He and Zhang.
Image: Photograph by Felice Frankel. Cover Design: David Shand.
|
MAC_Bench/Nature/Story/NATURE MATERIALS/17_2.txt
|
vith
|
17_2.txt
|
Phase engineering of 2D materials
A strategy of on-device phase engineering of two-dimensional materials is proposed, allowing the in situ realization of various lattice phases with distinct stoichiometries and versatile functions.
See Liu et al.
Image: Chaoyang Zhao, independent artist, and Junjie Shan, Nanjing University. Cover design: Alex Whitworth
|
MAC_Bench/Nature/Story/NATURE MATERIALS/23_3.txt
|
groundtruth
|
23_3.txt
|
train
|
Cell Chemical Biology
|
31_7
|
Which of the following options best describe the cover image?
|
MAC_Bench/Cell/Cover/Cell Chemical Biology/31_7.png
|
A
|
On the cover: Dual targeting of proteins (orange and blue) on the same cell surface
via bispecific antibodies (pink beige) holds great therapeutic promise with novel
modes of action that are rapidly advancing towards the clinic. Oslund et al. review the therapeutic impact of cis-targeting bispecific antibodies (pink beige)
in the clinic and their emerging applications and highlight features for enhancing
cis-targeting bispecific therapeutic development. Cover art created by Yi Zheng (yizhengillustration).
|
MAC_Bench/Cell/Story/Cell Chemical Biology/31_7.txt
|
groundtruth
|
31_7.txt
|
On the cover: Join us in celebrating the 30th anniversary of Cell Chemical Biology with this special issue. The imagery reflects the multidisciplinary nature of the
journal, spanning all areas of biological and biomedical sciences from academia to
industry, collectively forming the vibrant field of chemical biology. Dive into the
editorial to explore the journal's rich history, ongoing achievements, and future directions.
Cover art by Julie Sung.
|
MAC_Bench/Cell/Story/Cell Chemical Biology/31_5.txt
|
clip
|
31_5.txt
|
On the cover: After more than 20 years supporting the community of scientists dedicated
to research done at the interface of chemistry and biology, we bid farewell to Chemistry & Biology and introduce you to Cell Chemical Biology. We are excited about the new title that clearly reflects our commitment to chemical
biology and our alignment with the Cell Press family of journals. We are even more
excited about the exceptional science that we will continue to publish, and this special
issue highlights some of the areas in which chemical biology has been pushing the
limits and reaching for the blue skies.
|
MAC_Bench/Cell/Story/Cell Chemical Biology/23_12.txt
|
vith
|
23_12.txt
|
On the cover: Join us in celebrating the 30th anniversary of Cell Chemical Biology with this special issue. The imagery reflects the multidisciplinary nature of the
journal, spanning all areas of biological and biomedical sciences from academia to
industry, collectively forming the vibrant field of chemical biology. Dive into the
editorial to explore the journal's rich history, ongoing achievements, and future directions.
Cover art by Julie Sung.
|
MAC_Bench/Cell/Story/Cell Chemical Biology/31_4.txt
|
ave_1
|
31_4.txt
|
test
|
Nature Microbiology
|
10_2
|
Which of the following options best describe the cover image?
|
MAC_Bench/Nature/Cover/Nature Microbiology/10_2.png
|
D
|
Functional fluctuations in faecal flora
Longitudinal metagenomic and metatranscriptomic analyses of human faecal microbiomes reveal similar strain-level variation within and between individuals and allow dynamic functional variation to be tracked.
See Mehta et al. and Abu-Ali et al.
Image: Jason Lloyd-Price. Cover Design: Samantha Whitham.
|
MAC_Bench/Nature/Story/Nature Microbiology/3_10.txt
|
clip
|
3_10.txt
|
Functional roles in tree holes
Using natural tree-hole microbial communities, the authors show that bacterial abundance is related to their functional roles, with abundant phylotypes driving broad functional measures and rarer phylotypes implicated in more specialized measures.
See Rivett and Bell
Image: Thomas Bell. Cover Design: Samantha Whitham.
|
MAC_Bench/Nature/Story/Nature Microbiology/3_6.txt
|
vith
|
3_6.txt
|
Focus on microbial ecology
Microbes and viruses are abundant across terrestrial, freshwater and marine systems, and their behaviours have a profound influence on biogeochemical cycling, the climate, plant and agricultural productivity, and human and animal health. However, our understanding is plagued by unknowns regarding the nature of microbial interactions, the evolution and diversity of these communities, and best practices for studying and conceptualizing the complex dynamics of this unseen majority. This month’s focus issue features a set of Reviews, Perspectives and commentary that span microbial ecology from the organismal to the global scales, shining a light on the research questions that will guide the field.
See Editorial
Image and cover design: Alex Whitworth
|
MAC_Bench/Nature/Story/Nature Microbiology/9_5.txt
|
vitg
|
9_5.txt
|
Microbiome predicts potato growth potential
Pictured is an aerial image from a drone-mounted camera of a potato trial field. In this issue, Song et al. show that time-resolved drone imaging of potato crop development and seed tuber microbiome data can be used to predict potato vigour, or growth potential.
See Song et al.
Image: Elisa Atza, Technical University Delft. Cover design: Laoise Mac Gabhann
|
MAC_Bench/Nature/Story/Nature Microbiology/10_2.txt
|
groundtruth
|
10_2.txt
|
train
|
Nature Astronomy
|
8_5
|
Which of the following options best describe the cover image?
|
MAC_Bench/Nature/Cover/Nature Astronomy/8_5.png
|
B
|
Faster-than-fast blasts from the past
Fast radio bursts typically last milliseconds, with their durations connected in some way to the properties of their emitting regions, close to neutron stars or magnetars. But there have been hints of more rapid phenomena, and here Snelders et al., by re-analysing archival data, demonstrate the presence of microsecond-duration bursts that have been missed by previous searches.
See Snelders et al.
Image: Futselaar/ASTRON/NSF/NRAO/GBO. Cover design: Bethany Vukomanovic.
|
MAC_Bench/Nature/Story/Nature Astronomy/7_1.txt
|
vitg
|
7_1.txt
|
Studying accretion in extreme regimes
The Imaging X-ray Polarimetry Explorer has observed renowned Galactic X-ray binary Cygnus X-3, receiving photons reflected from the accretion funnel around the compact component. Accretion occurs at super-Eddington rates; the apparent luminosity makes Cygnus X-3 an ultraluminous X-ray source.
See Veledina et al.
Image: Alexander Mushtukov, University of Oxford ([email protected]). Cover design: Bethany Vukomanovic
|
MAC_Bench/Nature/Story/Nature Astronomy/8_5.txt
|
groundtruth
|
8_5.txt
|
A crescent-shaped heliosphere
3D magnetohydrodynamic simulations show that the heliosphere is not elongated and comet-like, but rather has a smaller crescent-like shape. The model agrees with observations obtained by Cassini, New Horizons, and the two Voyager spacecraft.
See Opher et al..
Image credit: Merav Opher, Boston University Cover Design: Allen Beattie.
|
MAC_Bench/Nature/Story/Nature Astronomy/4_6.txt
|
clip
|
4_6.txt
|
Out of the ordinary
Observations of a dusty high-redshift (z = 6) galaxy reveal it to be more representative of ‘normal’ star-forming galaxies in the local Universe, rather than the extreme starbursts of a similar age discovered to date. The cover image is an interpretation of this distant lensed galaxy by young illustrator Elda FloMont.
See Zavala et al.
Image: Elda FloMont, digital artist. Cover Design: Bethany Vukomanovic.
|
MAC_Bench/Nature/Story/Nature Astronomy/2_12.txt
|
vith
|
2_12.txt
|
train
|
Nature Reviews Cardiology
|
21_4
|
Which of the following options best describe the cover image?
|
MAC_Bench/Nature/Cover/Nature Reviews Cardiology/21_4.png
|
B
|
TGFβ in heart disease, inspired by the Review on p435.
Cover design: Vicky Summersby.
|
MAC_Bench/Nature/Story/Nature Reviews Cardiology/19_6.txt
|
ave_3
|
19_6.txt
|
Stress and cardiovascular disease, inspired by the Review on p603.
Cover design: Vicky Summersby
|
MAC_Bench/Nature/Story/Nature Reviews Cardiology/21_4.txt
|
groundtruth
|
21_4.txt
|
Noise pollution and cardiovascular risk, inspired by the Review on p619.
Cover design: Laura Marshall.
|
MAC_Bench/Nature/Story/Nature Reviews Cardiology/18_4.txt
|
clip
|
18_4.txt
|
Cardiovascular involvement in long COVID, inspired by the Review on p314.
Cover design: Vicky Summersby.
|
MAC_Bench/Nature/Story/Nature Reviews Cardiology/19_8.txt
|
vitg
|
19_8.txt
|
train
|
NATURE GENETICS
|
57_1
|
Which of the following options best describe the cover image?
|
MAC_Bench/Nature/Cover/NATURE GENETICS/57_1.png
|
D
|
Dynamic single-cell genetic effects
A new statistical method known as GASPACHO identifies nonlinear dynamic genetic effects using single-cell RNA-sequencing data.
See Kumasaka et al.
Image: Alamy. Cover Design: Tulsi Voralia.
|
MAC_Bench/Nature/Story/NATURE GENETICS/55_7.txt
|
ave_1
|
55_7.txt
|
Engineering crop polyploid genomes
Generation of clonal gametes in tomato enables polyploid genome design through controlled combination of pre-defined genome haplotypes.
See Wang et al.
Image: Rainer Franzen, Yazhong Wang and Rob Kesseler. Cover design: Tulsi Voralia
|
MAC_Bench/Nature/Story/NATURE GENETICS/56_7.txt
|
clip
|
56_7.txt
|
Mendel and memories
In celebration of the 200th anniversary of Gregor Mendel’s birth and the 30th anniversary of the launch of Nature Genetics, we look both forwards and backwards at how far the genetics field has come. This cover image is inspired by the cover of the first issue of Nature Genetics in 1992.
Image and Cover Design: Valentina Monaco.
|
MAC_Bench/Nature/Story/NATURE GENETICS/54_6.txt
|
vitg
|
54_6.txt
|
Blood DNA virome in COVID-19 and autoimmune diseases
Analysis of the blood DNA virome in patients with COVID-19 and autoimmune diseases associates endogenous HHV-6 and high anellovirus load with increased disease risk.
See Sasa et al.
Image: Itsuki Kitayama, STUDIO BIUM. Cover design: Tulsi Voralia
|
MAC_Bench/Nature/Story/NATURE GENETICS/57_1.txt
|
groundtruth
|
57_1.txt
|
train
|
One Earth
|
7_1
|
Which of the following options best describe the cover image?
|
MAC_Bench/Cell/Cover/One Earth/7_1.png
|
C
|
On the cover: The inaugural issue of One Earth focuses on climate action. Climate change is arguably the defining challenge of our
time, but more importantly, it is our inaction that will jeopardize the well-being
of future generations. Here, our cover depicts the generation at risk and their awareness
of, and engagement with, the climate issue while also reinterpreting the UN Sustainable
Development Goals' call for climate action icon (SDG 13).
|
MAC_Bench/Cell/Story/One Earth/1_4.txt
|
clip
|
1_4.txt
|
On the cover: Protecting the planet against further harm is critical, now more than
ever. To address the complex, interrelated, socio-environmental challenges threatening
societies and ecosystems, we need governance for sustainability. Image credit: Baac3nes
via Getty Images.
|
MAC_Bench/Cell/Story/One Earth/5_7.txt
|
ave_2
|
5_7.txt
|
On the cover: Soil, the earth beneath our feet, provides essential ecological services
for all life on Earth, but it is under immense pressure from anthropogenic activities.
Yet before we can effectively manage, protect, and restore our soils, we must first
develop a comprehensive understanding of soil health. Getty, Kami (Kuo, Jia-Wei).
|
MAC_Bench/Cell/Story/One Earth/7_1.txt
|
groundtruth
|
7_1.txt
|
On the cover: This year marks the completion of the first-ever Global Stocktake (GST)
of the Paris Agreement. While the GST has confirmed what is already known—progress
is thus far inadequate—it has also paved the way for ratcheted-up climate ambition.
On the cover, we feature art from Alisa Singer highlighting the potential for a realized
clean-energy transition. Entitled “Scaling up renewables is feasible” from her series,
“Environmental Graphiti – The Art of Climate Change,” the piece illustrates the recent
US precedents for natural gas and solar/wind expansion, indicating the feasibility
of ambitious buildout of large-scale renewable energy to meet the US 2035 carbon-pollution-free
power-sector target. This artwork is based on Figure 5 from the “The 2035 Report.”
Cover by Alisa Singer, http://www.environmentalgraphiti.org/, courtesy of the artist.
|
MAC_Bench/Cell/Story/One Earth/6_4.txt
|
ave_3
|
6_4.txt
|
train
|
Immunity
|
57_7
|
Which of the following options best describe the cover image?
|
MAC_Bench/Cell/Cover/Immunity/57_7.png
|
B
|
On the cover: 2024 marks the 30th anniversary of Immunity! To celebrate this milestone with the immunology community, we hosted an open call
for cover submissions for our special anniversary issue and are grateful to have received
beautiful and creative submissions from across the globe! The winning design featured
on the cover of this anniversary issue was designed by Yun Hsuan Elena Lin, a PhD
candidate in the laboratory of Dr. John Chang at the University of Californa, San
Diego. In her illustration, immune cells are depicted as flowers flourishing from
vases in the shape of the number 30. The stalks of the flowers are comprised of DNA,
RNA, mitochondria, antibodies, blood vessels, lymphatics, neuronal and glial cells,
microbes, and more, highlighting advances in immunology research over the past decades.
Model organisms populate the image as well, recognizing their key contributions in
driving substantial advances in human immunology. The bouquet captures the diversity
of immunological research published by Immunity, painted over a backdrop of dawn that symbolizes the exciting discoveries to come. In this issue, we present a collection of review and perspective articles on innate
immunity with a focus on pattern recognition. Rather than recognizing unique aspects
of a pathogen, the innate immune system uses families of receptors that recognize
shared features of potential threats to the host. Likewise, sensing of endogenous
molecular patterns enables maintenance of health. Throughout this collection of articles,
we explore the latest understanding of how the innate immune system evolved to ensure
that the body responds appropriately to the myriad of microbes in the environment
while maintaining regulation of homeostatic functions, how these mechanisms can go
awry in disease, and the prospects for harnessing these insights into the development
of new therapies.
|
MAC_Bench/Cell/Story/Immunity/57_9.txt
|
vitg
|
57_9.txt
|
On the cover: In this issue, Billipp et al. report the identification of a circuit wherein, upon detection of helminth infection,
tuft cells secrete acetylcholine that acts on neighboring epithelial cells to stimulate
chloride secretion. This then promotes the “weep” response and restricts helminth
infection, independently of other type 2 cells. The sentinel and effector functions
of epithelial tuft cells in host defense in the intestine are illustrated in the form
of Roman soldiers, where the apical “tuft” of microvilli are the plume on the centurion’s
helmet. An accompanying paper by Ndjim, Gasmi, Herbert, et al. reports similar findings.
Cover image by Lauren Hostette.
|
MAC_Bench/Cell/Story/Immunity/57_7.txt
|
groundtruth
|
57_7.txt
|
On the cover: 2019 marks the 25th anniversary of Immunity. The cover for this anniversary issue was designed to celebrate our authors, reviewers,
and readers and was created with photos submitted by immunology labs from around the
world (download the high-resolution image here). These photos, along with information about each lab, are compiled in a companion
website (https://www.cell.com/immunity/community) that we hope will serve as a resource to foster connections within the immunology
community. We thank all of the labs that participated in this effort—it has been fun!
In this issue, we also present to you fourteen commissioned reviews on the theme of
cytokines. These articles highlight the progress made in both the understanding of
these fundamental effectors of immunity and the translation of these insights into
the clinic. Cover design by Kavitha Scranton.
|
MAC_Bench/Cell/Story/Immunity/50_3.txt
|
clip
|
50_3.txt
|
On the cover: Establishment of long-lasting immunity depends on the generation of
germinal centers (GCs), microanatomical sites in which B cells improve their antibody
affinity over time. Pathogenic encounter and systemic inflammation, such as during
Salmonella Typhimurium infection, can compromise pre-existing GC reactions. In this issue, Biram et al.
(pages 442–458) show that disruption of GC reactions during bacterial infection depends
on the recruitment of Sca-1+ monocytes; GC B cells were incapable of adapting to the
metabolic alterations imposed by monocyte recruitment into lymphoid organs during
systemic inflammation. The mark left on host immunity by Salmonella Typhimurium interference of the antibody-mediated immune response is illustrated as a bacterium
(orange) in the context of disrupted GCs within Peyer’s patches. The background illustration
was designed based on GC visualization in the Peyer’s patches of mice infected with
S. Typhimurium. Bacterium figure was hand-drawn, inspired by electron microscopy images of S. Typhimurium. Image by Nitzan S. Biton and Adi Biram.
|
MAC_Bench/Cell/Story/Immunity/55_10.txt
|
ave_2
|
55_10.txt
|
train
|
Nature Reviews Neurology
|
21_1
|
Which of the following options best describe the cover image?
|
MAC_Bench/Nature/Cover/Nature Reviews Neurology/21_1.png
|
A
|
Brain diet, inspired by the Review on p5
Cover design: Amie Fernandez
|
MAC_Bench/Nature/Story/Nature Reviews Neurology/21_1.txt
|
groundtruth
|
21_1.txt
|
Modelling Alzheimer disease in a dish, inspired by the Review on p25.
Cover design: Philip Patenall.
|
MAC_Bench/Nature/Story/Nature Reviews Neurology/18_12.txt
|
vitg
|
18_12.txt
|
Brain diet, inspired by the Review on p5
Cover design: Amie Fernandez
|
MAC_Bench/Nature/Story/Nature Reviews Neurology/21_2.txt
|
clip
|
21_2.txt
|
Cholesterol in neurological disease, inspired by the Review on p583.
Cover design: Philip Patenall
|
MAC_Bench/Nature/Story/Nature Reviews Neurology/19_3.txt
|
ave_2
|
19_3.txt
|
train
|
Crystal Growth & Design
|
2025_3
|
Which of the following options best describe the cover image?
|
MAC_Bench/ACS/Cover/Crystal Growth & Design/2025_3.png
|
B
|
supramolecular polymeric motifs are combined in one crystal to produce the platforms for multimodal thermally tuned blue-to-green and/or NIR photoluminescence. The background of the cover image was generated by artificial intelligence (AI) using Microsoft Copilot.
|
MAC_Bench/ACS/Story/Crystal Growth & Design/2024_4.txt
|
vith
|
2024_4.txt
|
The pyrene-appended Fe(III) complex detects L-arginine compared to other amino acids via TURN-ON fluorescence through the Fe(III)/Fe(II) redox process. This graphic was created using Freepik’s AI Tool.
|
MAC_Bench/ACS/Story/Crystal Growth & Design/2025_3.txt
|
groundtruth
|
2025_3.txt
|
The cover shows two conformers of resorcinol and a single crystal of resorcinol polymorphs α grown in a high-pressure diamond-anvil cell. Resorcinol polymorphs were determined in the 1930s, but their metastable phases, symmetry, and densities have remained puzzling. The high-pressure structures reveal the mechanism destabilizing polymorphs α and β, involving the molecular conformation and directions of hydrogen bonds
|
MAC_Bench/ACS/Story/Crystal Growth & Design/2019_3.txt
|
clip
|
2019_3.txt
|
With the exploration of tyramine's role as a prolific coformer, this study delves into its extensive co-crystallization capabilities with diverse acids, analyzing crystal structures and electron density to uncover the key factors driving its versatility in multicomponent crystal formation.
|
MAC_Bench/ACS/Story/Crystal Growth & Design/2025_4.txt
|
vitg
|
2025_4.txt
|
train
|
One Earth
|
7_4
|
Which of the following options best describe the cover image?
|
MAC_Bench/Cell/Cover/One Earth/7_4.png
|
C
|
On the cover: This year marks the completion of the first-ever Global Stocktake (GST)
of the Paris Agreement. While the GST has confirmed what is already known—progress
is thus far inadequate—it has also paved the way for ratcheted-up climate ambition.
On the cover, we feature art from Alisa Singer highlighting the potential for a realized
clean-energy transition. Entitled “Scaling up renewables is feasible” from her series,
“Environmental Graphiti – The Art of Climate Change,” the piece illustrates the recent
US precedents for natural gas and solar/wind expansion, indicating the feasibility
of ambitious buildout of large-scale renewable energy to meet the US 2035 carbon-pollution-free
power-sector target. This artwork is based on Figure 5 from the “The 2035 Report.”
Cover by Alisa Singer, http://www.environmentalgraphiti.org/, courtesy of the artist.
|
MAC_Bench/Cell/Story/One Earth/6_4.txt
|
ave_2
|
6_4.txt
|
On the cover: This painting, and others in this series by John Sabraw, is inspired
by satellite imagery, dynamic flows of waterways, and the poetic beauty of complex
ecosystems. Sabraw incorporates sustainably sourced pigments that are extracted in
the process of remediating streams polluted from acid mine drainage from coal mining.
His collaborative team of engineers and environmentalists separate iron oxide pollutant
from clean water and transform it into safe and sustainable artist's pigment. As the
climate crisis continues to escalate, Sabraw's work offers an inspiring combination
of action, activism, and art that reminds us that there are many ways to make a difference.
For more of Sabraw's work, please visit https://www.johnsabraw.com/.
|
MAC_Bench/Cell/Story/One Earth/5_11.txt
|
ave_1
|
5_11.txt
|
On the cover: This month’s cover features The Role of Carbon Dioxide Removal from the series “Environmental Graphiti – The Art of Climate Change.” This artwork
is based on a figure from the United Nations Emission Gap Report 2017, which illustrates
the emission reductions from conventional mitigation technologies combined with carbon
dioxide removal (the black curve), against a business-as-usual scenario (the blue
curve), to keep global warming below 2°C relative to pre-industrial levels (with at
least 66% chance). Global net emissions levels turn to net zero and afterwards net
negative by the end of this century. Cover by Alisa Singer, http://www.environmentalgraphiti.org/, courtesy of the artist.
|
MAC_Bench/Cell/Story/One Earth/7_4.txt
|
groundtruth
|
7_4.txt
|
On the cover: The inaugural issue of One Earth focuses on climate action. Climate change is arguably the defining challenge of our
time, but more importantly, it is our inaction that will jeopardize the well-being
of future generations. Here, our cover depicts the generation at risk and their awareness
of, and engagement with, the climate issue while also reinterpreting the UN Sustainable
Development Goals' call for climate action icon (SDG 13).
|
MAC_Bench/Cell/Story/One Earth/1_4.txt
|
clip
|
1_4.txt
|
train
|
Trends in Microbiology
|
32_12
|
Which of the following options best describe the cover image?
|
MAC_Bench/Cell/Cover/Trends in Microbiology/32_12.png
|
B
|
This themed issue of Trends in Microbiology examines how single cells transition from one to many to exist within a community.
We also examine the benefits and challenges associated with living within a community.
Cover image from iStock/kpalimski.
|
MAC_Bench/Cell/Story/Trends in Microbiology/25_8.txt
|
vith
|
25_8.txt
|
The design of the cover image is based on Newton's cradle, which
is demonstrative of the conservation of momentum and energy. It is essential to
understand how microbes interact, assemble, and persist within microbial communities.
In the context of abundant and diverse commensal microbes in the host, enterococci,
as depicted as the lifted and released ball, drive the proliferation, pathogenicity
or
persistence of representative pathogens such as S. aureus, C. difficile and E. coli via metabolic cross-feeding, upregulation of virulence and biofilm formation, thus
influencing the progression of bacterial infections and affecting treatment options.
This
driving role of enterococci in polymicrobial infections is the subject of the review
by Xu
and colleagues. Image courtesy: Kui Zhu and Wenjiao Xu
|
MAC_Bench/Cell/Story/Trends in Microbiology/32_12.txt
|
groundtruth
|
32_12.txt
|
This themed issue of Trends in Microbiology examines the role that metabolism plays
in microbial life ranging from how microbes obtain energy to how microbes can alter
the metabolism of their host and use host-derived metabolites to their advantage.
The cover image was inspired by the hypothesis that perhaps pathogenic bacteria might
just be looking for food, which is discussed by Rohmer et al. on pages 341–348. Cover
image courtesy Rodolphe ‘Rodho’ Grandviennot.
|
MAC_Bench/Cell/Story/Trends in Microbiology/19_6.txt
|
vitg
|
19_6.txt
|
On pages 522–531, Stephanie Jones and Marie Elliot discuss the newly discovered explorer
cells in Streptomyces. Exploration in Streptomyces allows for rapid movement over a surface and occurs when there is a low level of
glucose. Cover image from iStock/hh5800.
|
MAC_Bench/Cell/Story/Trends in Microbiology/25_6.txt
|
clip
|
25_6.txt
|
train
|
Nature Cancer
|
5_6
|
Which of the following options best describe the cover image?
|
MAC_Bench/Nature/Cover/Nature Cancer/5_6.png
|
B
|
Five years of Nature Cancer
We mark Nature Cancer’s fifth anniversary with a Series of specially commissioned Reviews and opinion pieces on key developments in cancer research and oncology, together with a collection of primary research articles published in Nature Cancer over the past 5 years.
See our January Editorial
Image: Lukas Jonaitis / Alamy Stock Photo. Cover design: Allen Beattie
|
MAC_Bench/Nature/Story/Nature Cancer/6_1.txt
|
vith
|
6_1.txt
|
Mechano-metabolic programming of myeloid cells restricts tumor immunity
TGFβ-induced collagen deposition and metabolic programming of tumor-associated macrophages restricts the anti-tumor activity of CD8+ T cells in the breast cancer microenvironment.
See Tharp et al.
Image: Mary Kate Hayward. Cover design: Allen Beattie
|
MAC_Bench/Nature/Story/Nature Cancer/5_6.txt
|
groundtruth
|
5_6.txt
|
Stromal heterogeneity unraveled
Unravelling the dynamic changes in cancer-associated fibroblast subpopulations during breast cancer progression.
See Friedman et al..
Image: Genia Brodsky & Scherz-Shouval lab, Weizmann Institute of Science. Cover Design: Allen Beattie.
|
MAC_Bench/Nature/Story/Nature Cancer/1_6.txt
|
vitg
|
1_6.txt
|
Targeting tumor vascularization
De Palma and Hanahan outline the latest advances in understanding tumor angiogenesis and discuss therapeutic opportunities for targeting tumor vascularization.
See De Palma and Hanahan
Image: Mohammed Elamine ALIOUI / Alamy Stock Photo. Cover design: Allen Beattie
|
MAC_Bench/Nature/Story/Nature Cancer/5_7.txt
|
clip
|
5_7.txt
|
train
|
ACS Central Science
|
2025_1
|
Which of the following options best describe the cover image?
|
MAC_Bench/ACS/Cover/ACS Central Science/2025_1.png
|
A
|
Via synergistic photoredox/Brønsted acid catalysis, a novel three-component radical cascade reaction occurred through a radical addition/ring-opening/PCET-promoted radical–radical coupling protocol, affording an array of valuable enantioenriched
|
MAC_Bench/ACS/Story/ACS Central Science/2025_1.txt
|
groundtruth
|
2025_1.txt
|
Via synergistic photoredox/Brønsted acid catalysis, a novel three-component radical cascade reaction occurred through a radical addition/ring-opening/PCET-promoted radical–radical coupling protocol, affording an array of valuable enantioenriched
|
MAC_Bench/ACS/Story/ACS Central Science/2025_2.txt
|
clip
|
2025_2.txt
|
Shown in cartoon form is the key finding described by Yang et al., namely, that electron transfer between two pyrrole-based macrocycles and iodine can be readily controlled through the judicious choice of small molecule “players” and variations in the concentration. This work advances our understanding of fundamentals relevant to energy, catalysis, and molecular electronics.
|
MAC_Bench/ACS/Story/ACS Central Science/2024_7.txt
|
ave_2
|
2024_7.txt
|
A layer-blocked covalent organic framework (LB-COF) heterogenous film, synthesized via two successive surface-initiated polycondensations, shared superior photocatalytic uranium extraction performance as a result of the formation of a S-scheme heterojunction.
|
MAC_Bench/ACS/Story/ACS Central Science/2024_9.txt
|
ave_3
|
2024_9.txt
|
train
|
NATURE REVIEWS CANCER
|
24_6
|
Which of the following options best describe the cover image?
|
MAC_Bench/Nature/Cover/NATURE REVIEWS CANCER/24_6.png
|
C
|
There’s something fishy here, inspired by the Review on p263.
Cover design: Lara Crow.
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MAC_Bench/Nature/Story/NATURE REVIEWS CANCER/20_8.txt
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clip
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20_8.txt
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COVER: Slaying the senescent dragon, inspired by the Review on p340.
Cover design: David Johnston; cover concept: Liqin Wang.
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MAC_Bench/Nature/Story/NATURE REVIEWS CANCER/22_7.txt
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vith
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22_7.txt
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Thriving in an inhospitable environment, inspired by the Review on p448.
Cover design: Lara Crow
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MAC_Bench/Nature/Story/NATURE REVIEWS CANCER/24_6.txt
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groundtruth
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Modifications light up RNA, inspired by the Review on p303.
Cover design: Lara Crow.
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MAC_Bench/Nature/Story/NATURE REVIEWS CANCER/20_7.txt
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20_7.txt
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CELL RESEARCH
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34_7
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Which of the following options best describe the cover image?
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MAC_Bench/Nature/Cover/CELL RESEARCH/34_7.png
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B
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The cover uses a Chinese historical allusion of “beans casted on the ground magically turn into soldiers” to depict the intra-tumoral heterogeneity in pancreatic ductal adenocarcinoma and the battle between tumor cells (soldiers with shields) and T cells (soldiers with swords). See page 725-738 by Junya Peng et al. for details.
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MAC_Bench/Nature/Story/CELL RESEARCH/29_4.txt
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clip
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29_4.txt
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A Nian beast (proinflammatory PD-1+ T cells) wreaks havoc in the village (a metaphor for atherosclerosis, AS) on New Year's Eve. A man, dressed in red, ignites firecrackers (FcgR-binding anti-PD-1 mAb), preventing the Nian beast from causing trouble in the village (the shrinkage of AS plaques). See page 407–427 by Lin Fan et al. for details.
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MAC_Bench/Nature/Story/CELL RESEARCH/34_7.txt
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groundtruth
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34_7.txt
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The cover image illustrates the Lugou Bridge, which is one of the most famous scenic spots and the oldest existing stone arch bridge in Beijing. The stone lions carved above the stone guardrail are in different shapes, just like the heterogeneous fate choices of hemogenic endothelial cells on the way to become hematopoietic stem cells. See page 448–463 by Jun Xia et al. for details.
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The cover image illustrates how RNAi (terracotta warrior from Qin dynasty of China), as an "ancient" antiviral immunity mechanism, protects human neural progenitors (the wall) and brain organoids (beacon towers) from the invasion of Zika viruses. In antiviral RNAi, Dicer (the crossbow) produces viral siRNAs (the arrows) from viral dsRNA to specifically target and cleave viral genomic RNAs. Cover art is contributed by Dr. Yefei Li. See page 265-273 by Yan-Peng Xu et al. for details.
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MAC_Bench/Nature/Story/CELL RESEARCH/29_9.txt
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ave_1
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val
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Trendsin Neurosciences
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47_10
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Which of the following options best describe the cover image?
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MAC_Bench/Cell/Cover/Trendsin Neurosciences/47_10.png
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B
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Pyramidal neurons with active dendritic properties are found ubiquitously across the
neocortex. On pages 141–151, Matthew Larkum presents the hypothesis that both the
cellular properties and architecture of the cortex are tightly coupled, suggesting
a powerful operating principle of the cortex. The cover image shows layer 5 neocortical
pyramidal cells from different regions of the cortex coding for orientation, color
and form (of a tiger) while receiving feedback input (context) to the dendrites. An
artist's impression of a dendritic spike is shown in one of the pyramidal cells. Cover
design: Thomas Splettstoesser. Credit for the cloud image: Chris Schwarz (Shutterstock.com).
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MAC_Bench/Cell/Story/Trendsin Neurosciences/36_10.txt
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clip
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36_10.txt
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Microglia are the primary immune cells of the central nervous system
(CNS). Emerging evidence highlights the roles of homeostatic microglia in regulating
neuronal activity, interacting with synapses, tuning neural circuits, and modulating
behavior. In this issue of Trends in Neurosciences, Shunyi Zhao, Anthony Umpierre,
and Long-Jun Wu review how microglia sense and regulate neuronal activity through
synaptic interactions, thereby directly engaging with neural networks and influencing
behavior in adult mice. The cover features a 3D reconstructed two-photon image of
microglia (blue) interacting with cortical excitatory neurons and apical dendrites
(red).
The cover image was acquired and processed by Shunyi Zhao.
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MAC_Bench/Cell/Story/Trendsin Neurosciences/47_10.txt
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groundtruth
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47_10.txt
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Neural circuit function depends upon the precise composition and interconnectivity
of diverse cell populations. As conceptualized by the cover image, elucidating the
mechanisms governing circuit development and remodeling will provide researchers with
a blueprint for understanding both normal and pathological brain function. In this
Special Issue of Trends in Neurosciences all articles are devoted to providing an
overview of the latest research into the assembly and refinement of neural circuits.
Topics covered range from transcriptional control of cell fate and molecular control
of synapse assembly to circuit remodeling following learning, injury or disease. Cover
image: iStockphoto/roccomontoya
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MAC_Bench/Cell/Story/Trendsin Neurosciences/37_3.txt
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vith
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37_3.txt
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On The Cover: In this issue of Trends in Neurosciences, Jay Schulkin and Peter Sterling review recent evidence for allostasis, the efficient, anticipatory regulation of physiology. The brain predicts what will
be needed and, via myriad descending control mechanisms, including hypothalamus and
cerebral cortex, directs the neuroendocrine system and autonomic nervous system (see
cover) to deliver what is needed—just enough, just in time. This system minimizes
costly errors that need correction by feedback, i.e., homeostasis. Image credit: https://en.wikipedia.org/wiki/Autonomic_nervous_system, license type CC BY 3.0.
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MAC_Bench/Cell/Story/Trendsin Neurosciences/42_3.txt
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vitg
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42_3.txt
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train
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Nature Geoscience
|
17_5
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Which of the following options best describe the cover image?
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MAC_Bench/Nature/Cover/Nature Geoscience/17_5.png
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B
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The role of static versus dynamic stresses in earthquake clusters is unclear. Analysis of earthquakes triggered by a dyke intrusion at an Icelandic volcano unambiguously demonstrates that static stresses are important for earthquake clustering. The image shows the Holuhraun fissure eruption in Iceland on 2 September 2014.
Letter p629
IMAGE: BOB WHITE
COVER DESIGN: DAVID SHAND
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MAC_Bench/Nature/Story/Nature Geoscience/8_5.txt
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vitg
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8_5.txt
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Mapping Antarctica’s vegetation
Satellite-based mapping of vegetation shows that photosynthetic life occupies a total area of 44.2 km2 across Antarctica. This drone image reveals a striking landscape mosaic of mosses, lichens, and cyanobacteria covering ice-free areas of Robert Island, Antarctica — one of the most densely vegetated regions identified in the continent-wide mapping effort.
See Walshaw et al.
Image: Andrew Gray, Norsk institutt for naturforskning. Cover design: Alex Wing
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MAC_Bench/Nature/Story/Nature Geoscience/17_5.txt
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groundtruth
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17_5.txt
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High humidity in the warm Eocene
Early Eocene siderite spherules collected from Mount Blum, Washington State, United States, used to reconstruct past terrestrial temperature and hydroclimate conditions.
See van Dijk et al.
Image: Joep van Dijk, ETH Zürich. Cover Design: Thomas Phillips.
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MAC_Bench/Nature/Story/Nature Geoscience/13_2.txt
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clip
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13_2.txt
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Holocene temperature trends in the Arctic are unclear. An isotope record from ice wedges in Siberia suggests that winters have warmed since the mid-Holocene, whereas summer temperatures have cooled. The image shows a Pleistocene ice wedge on Muostakh Island, North Siberia, in August 2012.
Letter p122
IMAGE: THOMAS OPEL
COVER DESIGN: DAVID SHAND
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MAC_Bench/Nature/Story/Nature Geoscience/8_11.txt
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ave_2
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val
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Trends in Plant Science
|
29_4
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Which of the following options best describe the cover image?
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MAC_Bench/Cell/Cover/Trends in Plant Science/29_4.png
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C
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Two papers by Christoph-Martin Geilfus and colleagues and Muzammil Hussain, Dominique
Van Der Straeten and colleagues discuss the recent breakthrough discovery that stressed
plants emit various informative ultrasonic sound signals, which can be categorized
according to plant species, stress type, and stress severity. This unlocks a new path
into research of plant—environment interactions with multiple possibilities for future
applications. Image credit: Daniela Leitner (design) and Christoph-Martin Geilfus
(concept).
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MAC_Bench/Cell/Story/Trends in Plant Science/28_4.txt
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vitg
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28_4.txt
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The reviews in this issue are focussing on new emerging trends within the maturing
field of plant systems biology. In one of the reviews, on pages 212–221, Seung Yon
Rhee and Marek Mutwil introduce computational and statistical approaches and omics
data used for inferring gene function in plants, with an emphasis on network-based
inference. The authors also discuss caveats associated with network-based function
predictions such as performance assessment, annotation propagation, the guilt-by-association
concept, and the meaning of hubs. Finally, the authors note the current limitations
and possible future directions such as the need for gold standard data from several
species, unified access to data and tools, quantitative comparison of data and tool
quality, and high-throughput experimental validation platforms for systematic gene
function elucidation in plants. Cover design by Susanne C. Brink.
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MAC_Bench/Cell/Story/Trends in Plant Science/19_9.txt
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clip
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19_9.txt
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Most high-yielding crops are susceptible to abiotic and biotic stresses,
making them vulnerable to potential effects of climate change. A possible alternative
is
to accelerate the domestication of wild plants tolerant to harsh conditions and enhancing
their yields. However, competition between wild progenitors and newly domesticated
plants may reduce yields. To address this, Pedro M.P. Correia, Javad Najafi, and Michael
Palmgren propose using gene-editing to introduce traits into de novo domesticated
crops and make them visually distinct for weeding robots. By precise editing of key
genes for architectural traits and pigment accumulation, the plants' colors can be
altered. Manipulating these pivotal genes would significantly enhance the accuracy
of
discriminating between newly domesticated crops and their wild counterparts. Advanced
weeding robots could then be trained through machine learning methods to recognize
such signature traits. Image credit: Vibha Duraikkannan.
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MAC_Bench/Cell/Story/Trends in Plant Science/29_4.txt
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groundtruth
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29_4.txt
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Increasing evidence shows that many RNAs are targeted to specific locations within
cells, and that RNA-processing pathways occur in association with specific subcellular
structures. Therefore methods that allow the visualisation of RNA sequences within
a cellular context, and preferably at subcellular resolution, can help to answer important
questions in plant cell and developmental biology. On pages 196–203 Karl J. Oparka
and colleagues summarise approaches currently available for localising RNA in vivo
and address the specific limitations inherent with plant systems. Cover image provided
by Nynne Christensen (Tobacco trichome microinjected with genomic RNA of TMV. The
RNA, covalently labelled with a red fluorescent dye, forms granules that attach to
the actin–ER network. Also shown: chloroplast autofluorescence [blue] and the ER labelled
with a GFP fusion protein [green]). Cover design SCB.
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MAC_Bench/Cell/Story/Trends in Plant Science/15_9.txt
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ave_2
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15_9.txt
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train
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ACS Chemical Biology
|
2025_2
|
Which of the following options best describe the cover image?
|
MAC_Bench/ACS/Cover/ACS Chemical Biology/2025_2.png
|
C
|
DOI: 10.1021/cb1003652) reveal the biosynthetic pathway of a key autoinducer, CAI-1 associated with the life cycle and virulence of human pathogen, Vibrio cholerae. Cover art designed by Mable Fok.
|
MAC_Bench/ACS/Story/ACS Chemical Biology/2011_9.txt
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clip
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2011_9.txt
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This cover highlights the important role of phosphopantetheinylation of carrier protein in natural products biosynthesis, which is uncovered and harnessed by this study to activate cryptic/silenced natural products biosynthesis. Image credit: Benyin Zhang
|
MAC_Bench/ACS/Story/ACS Chemical Biology/2017_6.txt
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ave_2
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2017_6.txt
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Fluorescently labeled neutrophils (green) migrate from the blood island toward a tissue lesion generated by irradiating a small area of the fish with light, causing the production of cytotoxic radicals via activation of a photolatent BAPO compound.
|
MAC_Bench/ACS/Story/ACS Chemical Biology/2025_2.txt
|
groundtruth
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2025_2.txt
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screening of 41716 compounds in the nematode Caenorhabditis elegans identifies pre-clinical anticancer mycotoxins chaetocin and chetomin as potent inducers of novel nuclear metal homeostasis protein NUMR-1/2 in the alimentary canal. Chaetomiaceae fungi and C. elegans inhabit similar environments, raising the possibility that NUMR-1/2 functions as a resistance mechanism.
|
MAC_Bench/ACS/Story/ACS Chemical Biology/2024_8.txt
|
vith
|
2024_8.txt
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train
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Science Signaling
|
2007_391
|
Which of the following options best describe the cover image?
|
MAC_Bench/Science/Cover/Science Signaling/2007_391.png
|
D
|
ONLINE COVER This week features a Research Article that shows that the mitochondrial Ca2+ uniporter enables ATP production to match energy demands during the cell cycle. The image shows an artist's rendition of a mitotic cell. [Image: MedicalRF/Science Source]
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MAC_Bench/Science/Story/Science Signaling/12_579.txt
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clip
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12_579.txt
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ONLINE COVER This week features a Research Article that describes how, in addition to promoting translation, the kinase AKT also stimulates protein synthesis and cell growth by enhancing ribosome biogenesis. The image shows a ribosome translating a messenger RNA into protein. [Image: Peter Arnold, Inc./Alamy]
|
MAC_Bench/Science/Story/Science Signaling/4_188.txt
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vith
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4_188.txt
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ONLINE COVER This week features a Research Article that shows how inherited variations in mitochondrial DNA sequence, which correlate with the production of reactive oxygen species, shape gut microbiome species diversity in mice. The image is a scanning electron micrograph of a newborn baby's gut bacteria. [IMAGE: Steve Gschmeissner/Science Source]
|
MAC_Bench/Science/Story/Science Signaling/12_588.txt
|
vitg
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12_588.txt
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COVER This week features a Perspective on ubiquitination of the estrogen receptor by the BRCA1 complex. The image depicts a model of BRCA1 involvement in estrogen receptor ubiquitination. [Image: Christopher Bickel, AAAS]
|
MAC_Bench/Science/Story/Science Signaling/2007_391.txt
|
groundtruth
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2007_391.txt
|
val
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Environmental Science & Technology
|
2025_5
|
Which of the following options best describe the cover image?
|
MAC_Bench/ACS/Cover/Environmental Science & Technology/2025_5.png
|
C
|
This front cover depicts how machine learning and artificial intelligence are increasingly being applied to large environmentally relevant datasets for deciphering complex environmental relationships. The information uncovered and insights gained in system variables and behaviors help science discovery and solution advancement for environmental protection and sustainable development. ES&T is actively publishing transformational papers in this developing area of data science in environmental science and technology.
|
MAC_Bench/ACS/Story/Environmental Science & Technology/2022_11.txt
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clip
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2022_11.txt
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This ES&T special issue presents new research on persistent organic pollutants (POPs) from some of the leading experts in the field.
|
MAC_Bench/ACS/Story/Environmental Science & Technology/2021_11.txt
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vitg
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2021_11.txt
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This cover art showcases efforts to monitor CO2 emissions through the effective integration of multiple satellite measurements. It highlights an independent method for tracking progress in climate change mitigation.
|
MAC_Bench/ACS/Story/Environmental Science & Technology/2025_5.txt
|
groundtruth
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2025_5.txt
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Each year, ES&T selects exceptional papers from the previous year in the categories of Environmental Science, Environmental Technology, Environmental Policy, and Feature Articles for special recognition. This cover salutes the Best Papers of 201
|
MAC_Bench/ACS/Story/Environmental Science & Technology/2019_18.txt
|
vith
|
2019_18.txt
|
train
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Journal of Chemical Information and Modeling
|
2025_2
|
Which of the following options best describe the cover image?
|
MAC_Bench/ACS/Cover/Journal of Chemical Information and Modeling/2025_2.png
|
A
|
This figure shows materials being "scanned" by AI, as our method applies an AI-based filter to assess prediction reliability of AI-based regression models. The depicted structures are from the COD database (CC0 license) and were processed using the Avogadro software. View the article.
|
MAC_Bench/ACS/Story/Journal of Chemical Information and Modeling/2025_2.txt
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groundtruth
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2025_2.txt
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p 2666.
|
MAC_Bench/ACS/Story/Journal of Chemical Information and Modeling/2011_3.txt
|
vitg
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2011_3.txt
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, Z. Liu, and R. Wang, 2010, Vol. 50, Issue 9, pp 1682–1692.
|
MAC_Bench/ACS/Story/Journal of Chemical Information and Modeling/2011_10.txt
|
clip
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2011_10.txt
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We developed a new computational approach, EDES, based on enhanced-sampling MD simulations on a new set of collective variables. A key feature of EDES is the ability to generate “coconut-like” conformations of the binding site, that is relatively shrunk but accessible by ligands due to correct orientation of protein sidechains. EDES is able to enhance the sampling of druggable (including holo-like) conformations for proteins undergoing minor to large conformational changes upon ligand binding.
|
MAC_Bench/ACS/Story/Journal of Chemical Information and Modeling/2019_9.txt
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vith
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2019_9.txt
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train
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ACS Organic & Inorganic Au
|
2023_6
|
Which of the following options best describe the cover image?
|
MAC_Bench/ACS/Cover/ACS Organic & Inorganic Au/2023_6.png
|
D
|
Zinc(II) Complexes of SIRTi1/2 Analogues Transmetallating with Copper(II) Ions and Inducing ROS Mediated Paraptosis
|
MAC_Bench/ACS/Story/ACS Organic & Inorganic Au/2024_4.txt
|
ave_2
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2024_4.txt
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To form high-density metal/oxide interfacial active sites, we developed a catalyst preparation method based on hybrid clustering. An iridium-molybdenum
|
MAC_Bench/ACS/Story/ACS Organic & Inorganic Au/2023_2.txt
|
vitg
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2023_2.txt
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PET is a pernicious pollutant, that takes hundreds of years to break down, and accumulates in the environment. Most current strategies to recycle PET are both costly and ineffective, making enzymatic strategies to biodegrade PET particularly attractive. In particular, PET-degrading enzymes are conformationally flexible, and evolutionary conformational selection provides a strategy to enhance their activity. This, in turn, shines light on new paths to rescue our plastic-polluted oceans.
|
MAC_Bench/ACS/Story/ACS Organic & Inorganic Au/2023_5.txt
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clip
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2023_5.txt
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Convex-shaped Hammett plots allow to parametrize organic reactions and select the best catalysts for transformations with wide substrate scope, covering from electron-donor (ED) to electron-withdrawing functional groups (EWG).
|
MAC_Bench/ACS/Story/ACS Organic & Inorganic Au/2023_6.txt
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groundtruth
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2023_6.txt
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train
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Cancer Cell
|
42_1
|
Which of the following options best describe the cover image?
|
MAC_Bench/Cell/Cover/Cancer Cell/42_1.png
|
B
|
On the cover: The presentation of the CD44 variant (CD44v) licenses cancer cell (car)
to receive a supply of Cysteine (Cys) through the xCT cystine transporter (salesclerk).
CD44v stabilizes xCT at cell surface and thereby increases the intracellular amounts
of Cys for the synthesis of major antioxidant glutathione. Such CD44v-mediated antioxidative
action protects cancer cells from high levels of ROS in the tumor microenvironment.
See Ishimoto et al., 387–400. Artwork by Emi Kosano.
|
MAC_Bench/Cell/Story/Cancer Cell/19_4.txt
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clip
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19_4.txt
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On the cover: Yang et al. reveal a mechanism of immune evasion of tumor-initiating cells (TICs) and suggest
the strategy of combining CD155 blockade with anti-PD-1/PD-L1 therapy. The cover image
shows a cuckoo chick in a host bird’s nest, symbolizing CD49f+ TICs within the tumor microenvironment. The host bird represents neutrophils, attracted
to the cuckoo through its mimicry of the host’s calls, similar to how TICs release
CXCL2 to recruit neutrophils. The host then invests resources to feed the cuckoo,
paralleling neutrophils secreting CCL4 to support TIC survival. As the cuckoo matures,
its feathers (representing CD155) help it blend in and evade predators like the snake,
which symbolizes CD8+ T cells.
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MAC_Bench/Cell/Story/Cancer Cell/42_1.txt
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groundtruth
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42_1.txt
|
On the cover: After one of the most challenging years marked by the COVID-19 pandemic
and a call for social change to eliminate racism and increase diversity and equity
in science, we want to bring hope for 2021. This issue of Cancer Cell features a Voices
(pp. 1–2) discussing lessons learned in 2020 and upcoming changes in cancer research
and oncology to shine some light on the future ahead.
|
MAC_Bench/Cell/Story/Cancer Cell/39_12.txt
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vitg
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39_12.txt
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On the cover: With the festive red and gold theme of this cover, the Cancer Cell editorial team celebrates the new year and kicks off the celebration of Cancer Cell’s 20th anniversary, which will span 2022 with many exciting articles.
|
MAC_Bench/Cell/Story/Cancer Cell/40_12.txt
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vith
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40_12.txt
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val
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Accounts of Chemical Research
|
2024_19
|
Which of the following options best describe the cover image?
|
MAC_Bench/ACS/Cover/Accounts of Chemical Research/2024_19.png
|
D
|
Excited-state aromaticity, the reversal of ground-state aromaticity, can provide direct insight into excited-state properties. Recent verification for the excited-state aromaticity and new effective experimental strategies are discussed in this Account. See article by Dongho Kim and co-authors (10.1021/acs.accounts.7b00629). Cover art by Youngjae Kim.
|
MAC_Bench/ACS/Story/Accounts of Chemical Research/2018_7.txt
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vith
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2018_7.txt
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Aconitases are [4Fe–4S]2+ cluster-containing enzymes that are sensitive to metabolically-generated reactive species including superoxide radical (O2
|
MAC_Bench/ACS/Story/Accounts of Chemical Research/2019_4.txt
|
clip
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2019_4.txt
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–
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MAC_Bench/ACS/Story/Accounts of Chemical Research/2023_6.txt
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2023_6.txt
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The events occurring upon electron ionization span across 12 orders of magnitude in time, leading to the generation of numerous product ions detected by the mass spectrometer. Time-resolved measurements are helping scientists understand fragmentation patterns better and potentially impacting applications based on electron-initiated chemistry.
|
MAC_Bench/ACS/Story/Accounts of Chemical Research/2024_19.txt
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groundtruth
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2024_19.txt
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train
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Trends in Endocrinology & Metabolism
|
35_7
|
Which of the following options best describe the cover image?
|
MAC_Bench/Cell/Cover/Trends in Endocrinology & Metabolism/35_7.png
|
A
|
From the need for better preclinical models of disease to the use of new
technologies that can recapitulate the complexity of living systems, our approach
in
studying metabolic diseases is constantly being refined. This month, we focus on the
issue of modeling metabolism: our authors reflect on novel methodological approaches
in the study of endocrine and metabolic disorders and provide new frameworks to
address some of the current questions in diabetes, obesity, liver disease, cancer
metabolism and host-microbiome homeostasis. Our cover depicts this variety of
perspectives as building blocks of different colors and sizes that together contribute
a more comprehensive model of metabolism. Artwork credit: modified from Jobalou/
Getty Images.
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MAC_Bench/Cell/Story/Trends in Endocrinology & Metabolism/35_7.txt
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groundtruth
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35_7.txt
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This Special Issue of Trends in Endocrinology and Metabolism focuses on novel systems approaches for studying metabolic alterations in a high-throughput
scale. Leading experts review recent technological advances including analytical lipidomics
and the emerging area of in vivo lipid imaging, the genomics of voluntary exercise, cardiovascular disease and pediatric
obesity, new concepts in transcriptomics and phosphoproteomics, including new data
linking the microRNA interactome, RNA bindings proteins and the microbiome to metabolic
diseases. Cover mage is from iStockPhoto.
|
MAC_Bench/Cell/Story/Trends in Endocrinology & Metabolism/26_1.txt
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clip
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26_1.txt
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This Special Issue of Trends in Endocrinology and Metabolism focuses on a select list of GPCRs and their pivotal roles in a wide range of metabolic
processes, including glucose homeostasis and insulin secretion, appetite, calcium-sensing,
heart rate and blood pressure, sleep, to mention only a few. Our experts review the
most recent advances in these areas and offer forward-looking insights regarding the
actions of these key GPCRs in several metabolic and endocrine disorders. Cover image
was prepared by Effie Tzameli using the structure of the human beta-2 adrenergic receptor
in complex with the partial inverse agonist carazolol, licensed under the Creative
Commons Attribution-Share Alike 3.0 Unported license. Color scheme is from an Andy
Warhol painting image from Istockphoto.
|
MAC_Bench/Cell/Story/Trends in Endocrinology & Metabolism/27_4.txt
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vitg
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27_4.txt
|
This Special Issue of Trends in Endocrinology and Metabolism focuses on a select list of GPCRs and their pivotal roles in a wide range of metabolic
processes, including glucose homeostasis and insulin secretion, appetite, calcium-sensing,
heart rate and blood pressure, sleep, to mention only a few. Our experts review the
most recent advances in these areas and offer forward-looking insights regarding the
actions of these key GPCRs in several metabolic and endocrine disorders. Cover image
was prepared by Effie Tzameli using the structure of the human beta-2 adrenergic receptor
in complex with the partial inverse agonist carazolol, licensed under the Creative
Commons Attribution-Share Alike 3.0 Unported license. Color scheme is from an Andy
Warhol painting image from Istockphoto.
|
MAC_Bench/Cell/Story/Trends in Endocrinology & Metabolism/27_5.txt
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ave_1
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27_5.txt
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train
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Nature Chemistry
|
17_2
|
Which of the following options best describe the cover image?
|
MAC_Bench/Nature/Cover/Nature Chemistry/17_2.png
|
A
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Four-electron reduction of benzene
The reduction of benzene by molecular complexes remains a significant synthetic challenge, and it typically requires harsh reaction conditions involving group 1 metals. Now, a team led by Mathew Anker and Laurent Maron has shown that a highly polar organometallic samarium alkyl complex enables the four-electron reduction of benzene without the need for a group 1 metal. An artistic rendering of this reaction is pictured on the cover.
See Anker, Maron et al.
Image: Matthew Evans, Monash University. Cover design: Tulsi Voralia
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MAC_Bench/Nature/Story/Nature Chemistry/17_2.txt
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groundtruth
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17_2.txt
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Turning ten
This issue marks the 10th anniversary of the launch of Nature Chemistry. The cover features some of our favourite covers from the last decade, including one from each volume of the journal.
See Editorial
Image: polesnoy / Alamy Stock Photo. Cover Design: Tulsi Voralia
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MAC_Bench/Nature/Story/Nature Chemistry/11_9.txt
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vitg
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11_9.txt
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Complex terpene natural products are assembled in nature by reaction cascades that occur inside enzyme pockets that stabilize the cationic intermediates and transition states. Now Qi Zhang and Konrad Tiefenbacher have successfully mimicked this process inside a supramolecular assembly. As shown on the cover, six resorcinarene monomers self-assemble to form a cavity that can encapsulate a geranyl acetate substrate and catalyse its conversion to a variety of cyclic monoterpene natural products.Article p197;News & Views p187IMAGE: JOHANNES RICHERSCOVER DESIGN: ALEX WING
|
MAC_Bench/Nature/Story/Nature Chemistry/7_10.txt
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vith
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7_10.txt
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The magnetic properties of single-molecule magnets generally originate from a superexchange mechanism in which the spin states of two neighbouring metal ions couple to one another. Now, Long and co-workers have shown that a mixed-valence divanadium cluster with a bridging imidazolate ligand - shown on the cover of this issue - possesses a high-spin ground state that arises from a double-exchange mechanism based on electron delocalization. The versatility of imidazolate ligands in generating coordination complexes suggests that this could be a promising approach for producing a range of magnetic molecular materials. Cover image courtesy of Jeffrey D. rinehart.
Cover design by Alex Wing/Nature Chemistry.
Article p362
News & Views p351
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MAC_Bench/Nature/Story/Nature Chemistry/2_8.txt
|
clip
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2_8.txt
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train
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Inorganic Chemistry
|
2025_6
|
Which of the following options best describe the cover image?
|
MAC_Bench/ACS/Cover/Inorganic Chemistry/2025_6.png
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B
|
The cover illustrates the enlightenments gained on the development of earth-abundant Cr(III)-based emitters using bis(imidazolyl)-chelates. Those later enabled the preparation of the first homoleptic tris(didentate) Cr(III) compounds with a 6-membered ring chelate. This class of complexes was dominated so far by their 5-membered chelate rings counterparts (e.g., phenantroline, bipyridine).
|
MAC_Bench/ACS/Story/Inorganic Chemistry/2024_45.txt
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ave_2
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2024_45.txt
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Co-encapsulating ligands can facilitate tunable chemistry by bringing metals together. This cover, depicting a racing circuit, conveys the excitement of clocking both ligand and metal performance. As the associated paper shows, in this chemical race, acyclic ligands and trivalent cations are high performers. The cover was prepared with Adobe Illustrator and MidJourney.
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MAC_Bench/ACS/Story/Inorganic Chemistry/2025_6.txt
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groundtruth
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2025_6.txt
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The cover art shows the synthetic process of AB2-type arsines through benzodithiaarsole. This is an effective synthetic method because it is based on the abundant resource As2O3. A wide variety of arsenic ligands are now available as a result of this study.
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MAC_Bench/ACS/Story/Inorganic Chemistry/2022_8.txt
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clip
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2022_8.txt
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The cover illustrates the use of different acetylpyridine ligands in the design of two new cyanido-bridged Fe(II)−Ag(I) coordination polymers displaying thermally- and photo-induced spin crossover. The choice of the acetylpyridine ligand is the key to the observed properties. Cover art designed by Jezreel Parra and Carlos Cruz.
|
MAC_Bench/ACS/Story/Inorganic Chemistry/2024_15.txt
|
vitg
|
2024_15.txt
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val
|
Nature Reviews Endocrinology
|
20_12
|
Which of the following options best describe the cover image?
|
MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/20_12.png
|
D
|
Key advances in endocrinology, inspired by the Year in Reviews starting on p71
Cover design: Jennie Vallis
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MAC_Bench/Nature/Story/Nature Reviews Endocrinology/17_11.txt
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clip
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17_11.txt
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How to manage iatrogenic adrenal insufficiency, inspired by the Review on p209.
Cover design: Jennie Vallis
|
MAC_Bench/Nature/Story/Nature Reviews Endocrinology/20_9.txt
|
vith
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20_9.txt
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COVER: Modelling endometrial diseases, inspired by the Review on p727.
Cover design: Jennie Vallis.
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MAC_Bench/Nature/Story/Nature Reviews Endocrinology/18_1.txt
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ave_1
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18_1.txt
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The ageing thyroid, inspired by the Review on p5.
Cover design: Jennie Vallis
|
MAC_Bench/Nature/Story/Nature Reviews Endocrinology/20_12.txt
|
groundtruth
|
20_12.txt
|
val
|
Nature Metabolism
|
6_10
|
Which of the following options best describe the cover image?
|
MAC_Bench/Nature/Cover/Nature Metabolism/6_10.png
|
C
|
Maintaining mature melanocortin neurons
Hypothalamic melanocortin neurons control energy homeostasis by modulating appetite. Here the authors reveal a role of the transcription factor Tbx3 as a regulator of the peptidergic identity and function of immature and mature mouse melanocortin neurons.
See Quarta et al.
Image: Alexandre Fisette. Cover Design: Sam Whitham.
|
MAC_Bench/Nature/Story/Nature Metabolism/1_11.txt
|
clip
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1_11.txt
|
Vascular nutrient acquisition signals
Ong et al. demonstrate how YAP/TAZ and mTORC1 signalling intersect in endothelial cells to regulate nutrient acquisition and vascular growth. The cover depicts a mouse retina, labelled for PECAM (cyan), VE-cadherin (grey) and phosphorylated ribosomal protein S6 (red), indicating high mTORC1 signalling in angiogenic endothelial cells of the growing vascular network.
See Ong et al.
Image: Dr. Marco Castro, Angiogenesis & Metabolism Laboratory, Berlin Institute of Health at Charité, Universitätsmedizin Berlin and Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany. Cover Design: Thomas Phillips.
|
MAC_Bench/Nature/Story/Nature Metabolism/4_7.txt
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vitg
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4_7.txt
|
Bone-to-brain crosstalk
Bone-derived sclerostin accelerates the progression of Alzheimer’s disease (AD) by deregulating the Wnt–β-catenin signalling pathway in the brain. The image is a staining of the enzyme β-secretase (essential for AD pathogenesis) in a hippocampus section from a mouse model of AD.
See Shi et al.
Image: Baosheng Guo, Nanjing University. Cover Design: Thomas Phillips.
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MAC_Bench/Nature/Story/Nature Metabolism/6_10.txt
|
groundtruth
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6_10.txt
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Metabolizing alcohol via ALDH2 in cerebellar astrocytes
Jin et al. find that acetate produced by ALDH2 in cerebellar astrocytes contributes to the behavioural effects of alcohol.
See Jin et al.
Image: Science Photo Library / Alamy Stock Photo. Cover Design: Thomas Phillips.
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MAC_Bench/Nature/Story/Nature Metabolism/3_10.txt
|
vith
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3_10.txt
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train
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Journal of the American Chemical Society
|
2024_44
|
Which of the following options best describe the cover image?
|
MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2024_44.png
|
B
|
Mechanistic understanding of atom transfer radical polymerization (ATRP) is fundamental to predict and control polymerization outcomes and to guide the next advances in ATRP, which include using Fe catalysts, combining various stimuli, expanding the monomer and functionality scope, running it at larger or smaller scale, and developing controlled depolymerization procedures.
|
MAC_Bench/ACS/Story/Journal of the American Chemical Society/2022_18.txt
|
vith
|
2022_18.txt
|
While molecular marodipoles on average do not vary much with time (red line on the graph), they show huge picosecond fluctuations due to solvent dynamics (white line on the graph). View the article.
|
MAC_Bench/ACS/Story/Journal of the American Chemical Society/2024_44.txt
|
groundtruth
|
2024_44.txt
|
Through massive molecular dynamics simulations, it was found that the fluorine domain endows fluorinated ionic liquids ultrahigh solubility of nitrogen. Meanwhile, a theoretical model of fluorine densification energy was also constructed to predict the abnormal solubility of nitrogen based on the microscopic structure of fluorinated ionic liquids. View the article.
|
MAC_Bench/ACS/Story/Journal of the American Chemical Society/2024_15.txt
|
clip
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2024_15.txt
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A flow platform has been developed for the rapid assembly of polypeptides through native chemical ligation coupled with a novel photodesulfurization transformation. This technology was used to prepare the clinically approved HIV therapeutic enfuvirtide and the diagnostic agent somatorelin 2 orders of magnitude faster than traditional batch methods. See Payne and co-workers. DOI: 10.1021/jacs.8b03115. View the article.
|
MAC_Bench/ACS/Story/Journal of the American Chemical Society/2018_23.txt
|
vitg
|
2018_23.txt
|
train
|
Nature Human Behaviour
|
8_1
|
Which of the following options best describe the cover image?
|
MAC_Bench/Nature/Cover/Nature Human Behaviour/8_1.png
|
D
|
Exploring vast problem spaces
How do humans search for rewards in unfamiliar environments, where not all options can be exhaustively explored? Wu et al. show how a combination of generalization and optimistic sampling guides efficient human exploration in complex environments.
See Wu et al.
Image: Mike Ellis, The New Yorker © Conde Nast. Cover Design: Bethany Vukomanovic.
|
MAC_Bench/Nature/Story/Nature Human Behaviour/2_1.txt
|
ave_1
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2_1.txt
|
Nature Human Behaviour turns five
This month, we are celebrating our fifth anniversary with two dedicated Features. In one Feature, we asked 22 leading scientists in some of the key disciplines we cover to share their vision of the future of research in their disciplines. In a second Feature, past and present editors of the journal highlight some of their favourite papers and what made them special.
See Editorial, See also Box-Steffensmeier et al. and See also Antusch et al.
Cover image: incamerastock / Alamy Stock Photo. Cover design: Bethany Vukomanovic.
|
MAC_Bench/Nature/Story/Nature Human Behaviour/6_12.txt
|
clip
|
6_12.txt
|
Human behaviour and COVID-19
Human behaviour shapes the trajectory of pandemics, and behaviour is crucial to curb and contain disease spread. In this Focus, we bring together expert views from a broad range of disciplines across the behavioural and social sciences, to examine how individual and collective behaviour drive and can mitigate the COVID-19 pandemic.
Cover image: GeorgePeters/DigitalVision Vectors/Getty. Cover design: Bethany Vukomanovic
|
MAC_Bench/Nature/Story/Nature Human Behaviour/4_8.txt
|
ave_2
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4_8.txt
|
Executive function delays in neurodevelopmental conditions
Executive function delays are common in childhood neurodevelopmental conditions, such as autism, attention deficit hyperactivity disorder and tic disorders. However, it has been unclear whether delays in executive function development are a transdiagnostic feature of these conditions. Sadozai and colleagues address this question through a systematic review and meta-analysis of 180 studies. They find that, although there are a few differences among conditions, executive function delays are a transdiagnostic marker for neurodevelopmental conditions.
See Sadozai et al.
Image: Chris Sheng from Heifei Sondii Media Technology Co., Ltd. Cover design: Bethany Vukomanovic
|
MAC_Bench/Nature/Story/Nature Human Behaviour/8_1.txt
|
groundtruth
|
8_1.txt
|
train
|
Cell Reports Physical Science
|
5_6
|
Which of the following options best describe the cover image?
|
MAC_Bench/Cell/Cover/Cell Reports Physical Science/5_6.png
|
B
|
On the cover: A visual celebration of Cell Reports Physical Science’s fifth anniversary, featuring all of our covers from Volume 1, Issue 1 to December
2024’s Volume 5, Issue 12. We’d like to thank Cell Press’s own Philip Krzeminski for
his help in creating this beautiful cover.
|
MAC_Bench/Cell/Story/Cell Reports Physical Science/6_1.txt
|
clip
|
6_1.txt
|
On the cover: The cover, crafted by Guiyi Zhou, encapsulates the research of Xu et al. on leveraging advanced AI to transform polymeric gas separation membrane design.
It portrays a “polymer universe,” where dynamic interlocking yellow tracks represent
the complex polymer chains within an amorphous system. Shimmering stars scattered
throughout illustrate the gas molecules, emphasizing the focus on improving gas separation
efficiency. The spacecraft navigating this universe symbolizes the accelerating influence
of AI in propelling innovations in membrane technology.
|
MAC_Bench/Cell/Story/Cell Reports Physical Science/5_6.txt
|
groundtruth
|
5_6.txt
|
On the cover: A visual celebration of Cell Reports Physical Science’s fifth anniversary, featuring all of our covers from Volume 1, Issue 1 to December
2024’s Volume 5, Issue 12. We’d like to thank Cell Press’s own Philip Krzeminski for
his help in creating this beautiful cover.
|
MAC_Bench/Cell/Story/Cell Reports Physical Science/6_2.txt
|
ave_1
|
6_2.txt
|
On the cover: This month's issue of Cell Reports Physical Science features a special focus on aggregation induced emission. This collection of papers,
published alongside the rest of our great research articles and curated in collaboration
with Ben Zhong Tang and Dong Wang, brings together exciting fundamental and applied
research from this burgeoning field. Image credit: Dong Wang.
|
MAC_Bench/Cell/Story/Cell Reports Physical Science/3_11.txt
|
ave_2
|
3_11.txt
|
test
|
Journal of Chemical Theory and Computation
|
2024_2
|
Which of the following options best describe the cover image?
|
MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2024_2.png
|
A
|
Scanning the PDB and using QM calculations on the MP2/TZVPP level of theory, we highlight the geometric versatility and potential benefits of halogen–water interactions, trying to assess whether halogen bonding on water is more than a “drop in the ocean” for drug discovery.
|
MAC_Bench/ACS/Story/Journal of Chemical Theory and Computation/2024_2.txt
|
groundtruth
|
2024_2.txt
|
The
|
MAC_Bench/ACS/Story/Journal of Chemical Theory and Computation/2020_4.txt
|
vitg
|
2020_4.txt
|
A machine learning approach LINES is used to accelerate sampling of binding sites around TIM3 and P26. The strongest binding site is targeted and found to support stable binding in a pose that we hypothesize blocks TIM3-GAL9 binding, a reaction that is known to suppress immune responses.
|
MAC_Bench/ACS/Story/Journal of Chemical Theory and Computation/2023_7.txt
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clip
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2023_7.txt
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for clinical decision support. J. Chem. Theory Comput. 2017, 13, 210–222.
|
MAC_Bench/ACS/Story/Journal of Chemical Theory and Computation/2017_9.txt
|
vith
|
2017_9.txt
|
train
|
ACS Synthetic Biology
|
2024_12
|
Which of the following options best describe the cover image?
|
MAC_Bench/ACS/Cover/ACS Synthetic Biology/2024_12.png
|
A
|
Shining the spotlight on gene editors: optically controlled Cas9 and Cre provide precise spatiotemporal control over gene editing. The review discusses the methods for engineering the optical control of these enzymes. Why light? Clinical benefits? Any limitations? The future? Read more to find out!
|
MAC_Bench/ACS/Story/ACS Synthetic Biology/2024_12.txt
|
groundtruth
|
2024_12.txt
|
The cover art for this issue of ACS Synthetic Biology is part of the ACS Diversity and Inclusion Cover Art Series. The image, titled "Pipetting Hand," was created by Michael Rosnach,
|
MAC_Bench/ACS/Story/ACS Synthetic Biology/2024_9.txt
|
vith
|
2024_9.txt
|
The cover depicts a complex machine that generates new hues from combinations of primary colors. This process is analogous to the combinatorial engineering of biosynthetic genes to generate new molecules. Artwork by Marcela Vargas based on DOI: 10.1021/sb5003218.
|
MAC_Bench/ACS/Story/ACS Synthetic Biology/2015_7.txt
|
clip
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2015_7.txt
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In 2017, ACS Synthetic Biology had an amazing year, publishing more than 240 papers and sponsoring more than 10 conferences/events! We thank the authors, reviewers, and readers for your continued support of the journal and we look forward to working with you in 2018.
|
MAC_Bench/ACS/Story/ACS Synthetic Biology/2018_12.txt
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vitg
|
2018_12.txt
|
train
|
ACS Materials Letters
|
2024_7
|
Which of the following options best describe the cover image?
|
MAC_Bench/ACS/Cover/ACS Materials Letters/2024_7.png
|
C
|
In this Letter, Kumar et al. describe the use of intense light illumination to prepare atomically thin graphene, boron nitride, and MoS2 2D sheets via photoexfoliation, a novel scalable synthetic approach to achieve pure graphene and inorganic analogues. Credit: Shutterstock.com
|
MAC_Bench/ACS/Story/ACS Materials Letters/2022_11.txt
|
clip
|
2022_11.txt
|
Density functional theory + machine learning-based approaches are used to screen out suitable cathode hosts from a large number of MXenes for the optimum adsorption of possible intermediates in aluminum–sulfur batteries. AI was used partially in the creation of this cover graphic.
|
MAC_Bench/ACS/Story/ACS Materials Letters/2024_11.txt
|
vitg
|
2024_11.txt
|
A data-driven biomimetic approach is used to mimic the functionally graded structure of the Coscinodiscus species diatom for the design of architected honeycombs with tunable mechanical properties. The proposed approach leads to a novel design, which features a performance increase of 250% with respect to conventional honeycombs.
|
MAC_Bench/ACS/Story/ACS Materials Letters/2024_7.txt
|
groundtruth
|
2024_7.txt
|
In the article featured on the cover, the authors report the synthesis of an ionic liquid consisting of a polymerizable methacrylate with a thermally-labile Diels−Alder linkage between the ion-containing side chain and the polymer backbone. The cover illustration shows how, under UV light, the ionic liquid can be polymerized, and can then be induced to release ions in response to a thermal trigger. This ion release results in a clear increase in mobile ion content at the retro-Diels−Alder temperature which is retained after the material is returned to room temperature. This type of "triggerable" polymerizable ionic liquid has promise in next-generation responsive electronic devices.
|
MAC_Bench/ACS/Story/ACS Materials Letters/2020_9.txt
|
vith
|
2020_9.txt
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train
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Cell Systems
|
15_1
|
Which of the following options best describe the cover image?
|
MAC_Bench/Cell/Cover/Cell Systems/15_1.png
|
D
|
On the cover: Whole from many layers. Cell Systems invites readers to explore our pages, where we aim to cover outstanding research
toward understanding diverse systems and how their parts work together to shape the
behavior of the whole. Image courtesy of Janet Iwasa (http://onemicron.com/).
|
MAC_Bench/Cell/Story/Cell Systems/1_6.txt
|
ave_3
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1_6.txt
|
On the cover: Cell Systems turns one. This issue features a Focus on RECOMB (Li et al., 21–34; Sefer et al.,
35–42; El-Kebir et al., 43–53; Simmons et al., 54–61; Dao et al., 62–70) and our new
Tool article format (Durand et al., 95–98 and 99–101; Liepe et al., 102–107) and badge
(Ritchie et al., 71–82). They represent one aspect of our broader ambition to bridge
research fields (see our Editorial, 1–2), including between experimental and computational
biologists (see Voices, 7–11). Scan the QR code for a special anniversary message
from the editors.
|
MAC_Bench/Cell/Story/Cell Systems/3_6.txt
|
clip
|
3_6.txt
|
On the cover: Cell Systems is doing its part to keep the wheels of the scientific endeavor turning during the
COVID-19 pandemic. In this issue, Editor-in-Chief Quincey Justman (307) describes
our approach. Image credit: denisgo, Getty Images.
|
MAC_Bench/Cell/Story/Cell Systems/10_3.txt
|
vith
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10_3.txt
|
On the cover: Illustration of immunity and vaccination. This issue of Cell Systems focuses on systems immunology and includes a variety of primary research articles,
reviews, perspectives, and short pieces on the topic. Image credit: Getty.
|
MAC_Bench/Cell/Story/Cell Systems/15_1.txt
|
groundtruth
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15_1.txt
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train
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Developmental Cell
|
59_2
|
Which of the following options best describe the cover image?
|
MAC_Bench/Cell/Cover/Developmental Cell/59_2.png
|
A
|
On the cover: Even if tissue-specific multipotent stem cells are damaged and depleted,
the organism possesses the ability to regenerate multipotent stem cells. The cover
image illustrates the recovery process of intestinal stem cells damaged by irradiation
exposure. The image shows in situ hybridization of the small intestine (blue) prepared by a Swiss rolling technique
after irradiation, with stem cells marked by Olfm4 staining, in red. The merged image
with a stopwatch depicts the temporal recovery of intestinal stem cells over time.
To learn more about murine intestinal regeneration following tissue injury, see Ahn et al. Image credit: Sunghwan Bae.
|
MAC_Bench/Cell/Story/Developmental Cell/59_2.txt
|
groundtruth
|
59_2.txt
|
On the cover: An hourglass shows cells undergoing paligenosis, a cellular process
in which differentiated cells (mature, non-dividing) of diverse tissues and species
can return to proliferation again. An hourglass is mounted on a geared wheel within
a larger wheel, illustrating that the machinery underlying paligenosis allows cells
to cycle between differentiated and paligenotic states, which has important consequences
for regeneration, cancer, and aging. To learn more about the evolutionarily conserved
cellular mechanisms governing paligenosis, see Miao, Lewis, Cho et al. (pp. 178–194).
Cover image created in Adobe Photoshop by Macy E.-A. Mills; concept by Macy E.-A.
Mills and Jason C. Mills.
|
MAC_Bench/Cell/Story/Developmental Cell/55_5.txt
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ave_2
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55_5.txt
|
On the cover: In this issue we celebrate Developmental Cell's 20th anniversary year. The image depicts the fruits of the cell and developmental biology's
progress over the last two decades. Cell biology is represented by the epithelial
cell layer, development by Waddington's landscape, and a Tree of Knowledge to reflect
on growth and understanding of how cells and organisms respond to their environment.
Cover image drawn by Julie Sung (Scientific Illustrator at Cell Press).
|
MAC_Bench/Cell/Story/Developmental Cell/56_2.txt
|
ave_1
|
56_2.txt
|
On the cover: Developmental Cell publishes papers representing a full range of cell biology and development, from
molecular mechanism to organismal pathophysiology. The spiraling elements depicted
on the cover of this month's tenth anniversary issue suggest a continuum of relationships
amongst these intertwined disciplines. Cover image created by Kate Mahan and Yvonne
Blanco.
|
MAC_Bench/Cell/Story/Developmental Cell/21_6.txt
|
clip
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21_6.txt
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train
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Nature Reviews Neurology
|
21_2
|
Which of the following options best describe the cover image?
|
MAC_Bench/Nature/Cover/Nature Reviews Neurology/21_2.png
|
A
|
Brain diet, inspired by the Review on p5
Cover design: Amie Fernandez
|
MAC_Bench/Nature/Story/Nature Reviews Neurology/21_2.txt
|
groundtruth
|
21_2.txt
|
Cholesterol in neurological disease, inspired by the Review on p583.
Cover design: Philip Patenall
|
MAC_Bench/Nature/Story/Nature Reviews Neurology/19_3.txt
|
ave_2
|
19_3.txt
|
Brain diet, inspired by the Review on p5
Cover design: Amie Fernandez
|
MAC_Bench/Nature/Story/Nature Reviews Neurology/21_1.txt
|
clip
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21_1.txt
|
Modelling Alzheimer disease in a dish, inspired by the Review on p25.
Cover design: Philip Patenall.
|
MAC_Bench/Nature/Story/Nature Reviews Neurology/18_12.txt
|
vitg
|
18_12.txt
|
val
|
BDJ
|
237_3
|
Which of the following options best describe the cover image?
|
MAC_Bench/Nature/Cover/BDJ/237_3.png
|
C
|
In this issue
This issue features articles on dentistry during the COVID-19 pandemic, the impact of COVID-19 on BAME dental professionals, and domestic violence during the pandemic.
Image credit: Joanna Culley
|
MAC_Bench/Nature/Story/BDJ/228_1.txt
|
clip
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228_1.txt
|
In this issue
This issue features articles on COVID-19, stress and Brexit.
Image credit: Rachel Jackson
|
MAC_Bench/Nature/Story/BDJ/229_4.txt
|
vith
|
229_4.txt
|
In this issue
This issue features articles on peri-implantitis, implant-supported overdentures, and AI in oral medicine.
Cover image: From 2021. Our 2021 cover series recognising the strains placed on dental professionals in the wake of the coronavirus pandemic aimed to focus attention not only on the crossinfection control measures but also on the consequent human pressures. The cover on this issue (incorporating Vol 230 Issue 5, 12 March 2021) adds visual clues to some of the challenges we experienced in publishing during the pandemic.
©Tim Marrs, incorporating original photography by Filip Gierlinski
|
MAC_Bench/Nature/Story/BDJ/237_3.txt
|
groundtruth
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237_3.txt
|
In this issue
This issue features articles on COVID and the use of paracetamol, COVID and medical emergencies, and desquamative gingivitis.
Image credit: Rachel Jackson
|
MAC_Bench/Nature/Story/BDJ/229_12.txt
|
ave_1
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229_12.txt
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train
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Nature Machine Intelligence
|
6_5
|
Which of the following options best describe the cover image?
|
MAC_Bench/Nature/Cover/Nature Machine Intelligence/6_5.png
|
C
|
Neural architecture search for computational genomics
Applying deep learning models requires the tuning of network architectures for optimum performance, which can require substantial machine learning expertise. In this issue, Zijun Zhang et al. present a fully automated framework, AMBER, to design and apply convolutional neural networks for genomic sequences using neural architecture search. In an accompanying News & Views, Yi Zhang, Yang Liu and X. Shirley Liu discuss the AMBER technique and its potential to improve deep learning models in genomics.
See Zhang et al. and Zhang, Liu and Liu
Image: Simons Foundation. Cover design: Lauren Heslop.
|
MAC_Bench/Nature/Story/Nature Machine Intelligence/3_8.txt
|
vitg
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3_8.txt
|
Looking for the right questions
Machine learning offers a powerful tool to scientists for probing data. But these tools must be developed with the right questions in mind. This issue features a Perspective exploring the challenges for social sciences to connect to AI research, a Comment from conservation ecologists urging a focus on the right metrics and ethical approach for applying machine learning ‘in the wild’, and the next instalment of our Challenge Accepted series, highlighting the challenge of finding the right question — and prize — when organizing data science competitions.
Image: Gonzalo Rodriguez Gaspar, GRG Studios. Cover Design: Karen Moore.
|
MAC_Bench/Nature/Story/Nature Machine Intelligence/1_11.txt
|
vith
|
1_11.txt
|
Examining dataset responsibility in machine learning
Machine learning and deep learning algorithms depend on high-quality training data. Mittal et al. present a large audit of computer vision datasets and highlight the vital role of responsible databases in machine learning, emphasizing fairness, privacy and regulatory compliance. These principles are crucial for developing AI systems that are both effective and ethically sound.
See Mittal et al.
Image: Surbhi Mittal, IIT Jodhpur. Cover design: Emily Paul
|
MAC_Bench/Nature/Story/Nature Machine Intelligence/6_5.txt
|
groundtruth
|
6_5.txt
|
Learning from human decision making
Artificial intelligence and machine learning systems may surpass human performance on a variety of tasks, but they may also mimic or amplify human errors or biases. This issue of Nature Machine Intelligence features a Perspective describing decades of research by psychologists on the development and prevention of errors and biases in human judgment and decision making. The authors provide connections between the psychology and machine learning literatures, and offer guideposts for the development and improvement of machine learning algorithms.
See Alexander S. Rich and Todd M. Gureckis
Image: Exdez/DigitalVision Vectors/Getty images. Cover design: Karen Moore
|
MAC_Bench/Nature/Story/Nature Machine Intelligence/1_9.txt
|
clip
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1_9.txt
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train
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ACS Biomaterials Science & Engineering
|
2024_5
|
Which of the following options best describe the cover image?
|
MAC_Bench/ACS/Cover/ACS Biomaterials Science & Engineering/2024_5.png
|
A
|
The visual represents the groundbreaking fabrication of 3D polycaprolactone macrostructures by 3D electrospinning. Highlighted are the optimal parameters that enable the precise construction of uniform, hydrophilic scaffolds, suitable for enhanced cell penetration and growth
|
MAC_Bench/ACS/Story/ACS Biomaterials Science & Engineering/2024_5.txt
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groundtruth
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2024_5.txt
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marine-derived polysaccharides
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MAC_Bench/ACS/Story/ACS Biomaterials Science & Engineering/2016_1.txt
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clip
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2016_1.txt
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As a kind of facile tool, microfluidic paper-based analytical devices (μPADs) have been widely used in analytical and biomedical fields. However, limited flow control ability hinders their use in biofluidics fields, which require continuous perfusion. Here, the authors designed a novel, low-cost, and compact platform to address this problem. This platform has the potential to integrate with bioprinting and organ-on-a-chip, and can be developed into an organ-on -μPADs system. As most of the parts of this platform can be created using a three-dimensional (3D) desktop printer, it can be easily duplicated by other researchers.
|
MAC_Bench/ACS/Story/ACS Biomaterials Science & Engineering/2017_9.txt
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vith
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2017_9.txt
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A promising extrusion system based on an interfacial diffusion printing technique for one-step printing of tubular tissue grafts is proposed. The hydrogel grafts with the capability of enduring arterial pressure are mechanically stable in rabbit carotid artery replacement. Τhis work putσ forward a new bioengineering platform including high-performance materials and convenient techniques for small-diameter vascular grafts suitable for the coronary artery bypass grafting surgery.
|
MAC_Bench/ACS/Story/ACS Biomaterials Science & Engineering/2019_1.txt
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vitg
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2019_1.txt
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train
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ACS Macro Letters
|
2025_1
|
Which of the following options best describe the cover image?
|
MAC_Bench/ACS/Cover/ACS Macro Letters/2025_1.png
|
C
|
Aqueous photoiniferter polymerization of acrylonitrile, achieving high monomer conversion, faster kinetics, and controlled molecular weights, could dramatically improve polyacrylonitrile-based polymers for high-performance carbon fiber production. The AI-generated cover depicts black carbon fibers being pulled out of a beaker of shimmering saltwater, highlighting the potential application of this work.
|
MAC_Bench/ACS/Story/ACS Macro Letters/2024_1.txt
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clip
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2024_1.txt
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Polymer-protein conjugate particles with biocatalytic activity prepared by Schiff base synthesis can efficiently stabilize water-in-water emulsions. Considering the characteristics of all-aqueous, compartmental
|
MAC_Bench/ACS/Story/ACS Macro Letters/2017_6.txt
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vitg
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2017_6.txt
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Allying intramolecular transesterification (the backbiting side reaction) with a compositionally distinct star-shaped macroinitiator is proven particularly effective for the synthesis of cyclic alternating copolymers. The substantially enlarged solubility difference between the cyclic and acyclic part of the product significantly facilitates their separation by simple precipitation treatments.
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MAC_Bench/ACS/Story/ACS Macro Letters/2025_1.txt
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groundtruth
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2025_1.txt
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Dynamic covalent bonds can be incorporated into polymer networks for a host of applications. In this Viewpoint, Evans and coworkers describe the outlook for this class of polymers and highlight key questions regarding how dynamic bonds impact self-assembly, viscoelasticity, and functionality of dynamic polymer networks.
|
MAC_Bench/ACS/Story/ACS Macro Letters/2022_9.txt
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ave_0
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2022_9.txt
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train
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One Earth
|
7_8
|
Which of the following options best describe the cover image?
|
MAC_Bench/Cell/Cover/One Earth/7_8.png
|
B
|
On the cover: Decarbonizing cities could hold the key to the successful reduction
of greenhouse gas emissions. However, cities are complex, multifaceted entities. A
systems approach is needed to help identify patterns among the chaos. Credit: Mikhail
Derevyanov/EyeEm via Getty Images.
|
MAC_Bench/Cell/Story/One Earth/5_6.txt
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clip
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5_6.txt
|
On the cover: The chemical sector is a vital pillar of modern society, providing goods
and services that meet the everyday needs of the individual and offer solutions to
society-wide challenges: healthcare, agriculture, manufacturing, energy, and water
treatment, to name a few. Yet there are also trade-offs and externalities: emissions,
pollutants, and wastes are synonymous with today's chemical operations. A responsible
and sustainable future will only be realized if the chemical sector embraces circularity.
Hal Bergman for Getty Images.
|
MAC_Bench/Cell/Story/One Earth/7_8.txt
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groundtruth
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7_8.txt
|
On the cover: The inaugural issue of One Earth focuses on climate action. Climate change is arguably the defining challenge of our
time, but more importantly, it is our inaction that will jeopardize the well-being
of future generations. Here, our cover depicts the generation at risk and their awareness
of, and engagement with, the climate issue while also reinterpreting the UN Sustainable
Development Goals' call for climate action icon (SDG 13).
|
MAC_Bench/Cell/Story/One Earth/1_4.txt
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vitg
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1_4.txt
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On the cover: Protecting the planet against further harm is critical, now more than
ever. To address the complex, interrelated, socio-environmental challenges threatening
societies and ecosystems, we need governance for sustainability. Image credit: Baac3nes
via Getty Images.
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MAC_Bench/Cell/Story/One Earth/5_7.txt
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ave_2
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5_7.txt
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train
|
JACS Au
|
2025_1
|
Which of the following options best describe the cover image?
|
MAC_Bench/ACS/Cover/JACS Au/2025_1.png
|
A
|
This experimental and theoretical study investigates design factors for the preparation of cadmium coordination polymers (CPs) containing fluorene and fluorenone cores as single-crystal optical waveguides. The CPs exhibit exceptional light propagation with one of the lowest optical losses for CPs and organic waveguides, providing insights for future design and optimization. The cover artwork was made by Daniele Mele. Some of the layers were generated by means of Google Gemini and Playground AI tools.
|
MAC_Bench/ACS/Story/JACS Au/2025_1.txt
|
groundtruth
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2025_1.txt
|
This cover is part of ACS's Diversity & Inclusion Cover Art Series. Read more in the accompanying Editorial entitled “Ladies Are So Essential in Research (LASER).
|
MAC_Bench/ACS/Story/JACS Au/2023_12.txt
|
clip
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2023_12.txt
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Featured on this cover is a novel doping strategy, photoexcitation-assisted molecular doping (PE-MD), which is built upon the familiar mechanism of photoinduced electron transfer. The application of PE-MD to the PDPP4T polymer significantly amplifies its doping level, facilitating efficient thermoelectric conversion for clean energy.
|
MAC_Bench/ACS/Story/JACS Au/2024_3.txt
|
vith
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2024_3.txt
|
This cover art showcases the enhanced catalytic activity of Mo2C for selective hydrogenation of CO2 through metal defects, induced by a combination of carbon support and the carbonization process. These defects facilitate CO desorption with reduced magnetization at the active site and effectively promote surface hydrogen migration by neutralizing the atomic charge.
|
MAC_Bench/ACS/Story/JACS Au/2023_3.txt
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vitg
|
2023_3.txt
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train
|
Trends in Immunology
|
45_10
|
Which of the following options best describe the cover image?
|
MAC_Bench/Cell/Cover/Trends in Immunology/45_10.png
|
B
|
Central to survival is the ability to sense, interpret and respond to stimuli from
the environment, largely the work of the nervous and immune systems. In this Special
Issue, Trends in Immunology explores how these neuroimmune interactions build and maintain system homeostasis,
and influence what happens in disease. Cover image by Avi Friedlich based on a fluorescence
micrograph of immune cells in the meningeal lymphatics of a mouse model of multiple
sclerosis, generously supplied by Jonathan Kipnis and Antoine Louveau. An assembly
of dot-plots generated from the DNA sequence of the CD4 gene was repeatedly rotated
in space, and the resulting image was layered on the micrograph, with adjustments
for size and color. You can see more art by Avi at http://www.behance.net/friedlich.
|
MAC_Bench/Cell/Story/Trends in Immunology/36_3.txt
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vitg
|
36_3.txt
|
Our special issue on ‘Neuroimmunology – I’ showcases current research
in this discipline, emphasizing the reciprocal interplay between the brain and our
nervous
systems (central or peripheral). Various cells that act as partners and guardians
of our
nervous and immune systems, e.g., microglia, are highlighted. The articles presented
here unveil key research avenues that may enable a better understanding of neurological
and neuroimmune-related disorders. The cover image reflects the metamorphosis and
tessellation technique developed by Escher; here, a neuron gradually fills in the
gaps
between immune cells, and vice versa. Image credit: Felipe A. Pinho-Ribeiro.
|
MAC_Bench/Cell/Story/Trends in Immunology/45_10.txt
|
groundtruth
|
45_10.txt
|
Our special issue on ‘Neuroimmunology – I’ showcases current research
in this discipline, emphasizing the reciprocal interplay between the brain and our
nervous
systems (central or peripheral). Various cells that act as partners and guardians
of our
nervous and immune systems, e.g., microglia, are highlighted. The articles presented
here unveil key research avenues that may enable a better understanding of neurological
and neuroimmune-related disorders. The cover image reflects the metamorphosis and
tessellation technique developed by Escher; here, a neuron gradually fills in the
gaps
between immune cells, and vice versa. Image credit: Felipe A. Pinho-Ribeiro.
|
MAC_Bench/Cell/Story/Trends in Immunology/45_9.txt
|
clip
|
45_9.txt
|
Stemming from an overactivated immune system, cytokine storms (CS) are associated
with various pathologies, including infectious diseases (e.g. COVID-19), certain immunodeficiencies,
autoinflammatory diseases, or following therapeutic interventions. On pages 681–705,
Rajendra Karki and Thirumala-Devi Kanneganti discuss recent progress in innate immunity
and inflammatory cell death, providing insights into the cellular and molecular mechanisms
of CS and a possible rationale for future therapeutic discovery and development. Image
credit: gettyimages/andersborman. Cover design: Catarina Sacristán.
|
MAC_Bench/Cell/Story/Trends in Immunology/42_5.txt
|
vith
|
42_5.txt
|
train
|
Cancer Cell
|
42_9
|
Which of the following options best describe the cover image?
|
MAC_Bench/Cell/Cover/Cancer Cell/42_9.png
|
C
|
On the cover: Immune cells are major defenders of our body but are often turned into
protectors (symbolized by the hairy cell holding a shield) of tumors (symbolized by
the crab) as well as promoting tumor progression. Decades of research in immunology
have led to the development of many immunotherapeutic approaches (symbolized by the
cells holding swords), some of which have shown encouraging clinical results in recent
years. This issue presents three Perspectives, two Articles, and three Previews illustrating
the progress in cancer immunotherapy and is published in conjunction with the April
Trends in Immunology special issue on immunity and cancer. Cover concept by Seth B. Coffelt and Karin
E. de Visser; cover artwork by Tomasz Ahrends.
|
MAC_Bench/Cell/Story/Cancer Cell/27_3.txt
|
vith
|
27_3.txt
|
On the cover: Defeating a complex disease like cancer will require a united, concerted
effort by different types of people from diverse backgrounds who can bring together
distinctive experiences and ways of thinking. This issue of Cancer Cell features Voices, Letter, and Commentary pieces discussing the importance of diversity
and immigration for the future of cancer research.
|
MAC_Bench/Cell/Story/Cancer Cell/38_4.txt
|
clip
|
38_4.txt
|
On the cover: In this issue of Cancer Cell, two papers by Barisic et al. and Deng et al. evaluate how mutations in components of the BAF complex lead to the development of
B cell malignancies. In the cover, Barisic et al. demonstrate that ARID1A is required
for continuous eviction of nucleosomes, facilitating the sequential binding of transcription
factors necessary for safeguarding germinal center B cell fate towards plasma cells.
The cover image symbolizes ARID1A as Sisyphus, exerting significant effort and energy
to push boulders uphill, analogous to the BAF complex and ARID1A using energy from
ATP hydrolysis for nucleosome eviction. Birds in the image symbolize the antibodies
produced by plasma cells when ARID1A effectively remodels nucleosomes. Credit: Art
by Inmywork Studio.
|
MAC_Bench/Cell/Story/Cancer Cell/42_9.txt
|
groundtruth
|
42_9.txt
|
On the cover: In this issue of Cancer Cell, Sagnella et al. (pp. 354–370) show that nanocells attack tumors by delivering a
cytotoxin and engaging multiple arms of the immune system. The cytotoxin binds and
kills tumor cells. Dendritic cells and macrophages engulf dying tumor cells and display
tumor-associated antigens that are recognized by CD8+ T cells. Activated CD8+ T cells
home to the tumor, recognizing and killing live tumor cells and augmenting the anti-tumor
effect. The cover is an artistic rendition of the dual roles of the cyto-immunotherapeutic
nanocells. Design: Himanshu Brahmbhatt and Jennifer MacDiarmid. Image: Martin Hale,
Animated Biomedical Productions.
|
MAC_Bench/Cell/Story/Cancer Cell/37_4.txt
|
vitg
|
37_4.txt
|
train
|
ACS Food Science & Technology
|
2024_5
|
Which of the following options best describe the cover image?
|
MAC_Bench/ACS/Cover/ACS Food Science & Technology/2024_5.png
|
D
|
Factors contributing to honey botanical origin and volatile fingerprint: (1)
|
MAC_Bench/ACS/Story/ACS Food Science & Technology/2024_10.txt
|
clip
|
2024_10.txt
|
This study determined the efficacy of carotenes in modulating molecular targets in a hydrogen peroxide (H2O2)-induced AMD in vitro model. To evaluate cytotoxicity, a panel of 17 human cancer cells and non-cancerous human retinal pigment epithelium (ARPE-19) cells were treated with carotenes. A polymerase chain reaction (PCR) array study was conducted to evaluate the efficacy of carotenes in modulating oxidative stress, and its underlying molecular targets were also studied using bioinformatic analyses through reactome pathway analysis and targeted cell-based reporter assays.
|
MAC_Bench/ACS/Story/ACS Food Science & Technology/2022_2.txt
|
vith
|
2022_2.txt
|
This illustration, created using the "Image Creator from Playground AI" tool, vividly represents the theme of our study. It features a cup of dark tea, with steam symbolizing warmth and health, alongside a healthy-looking white rat. The graphic contrasts this with an image of a lethargic white rat, representing the condition before dark tea consumption. Additionally, it includes a graph or infographic indicating improvements in glucose levels or other diabetic markers in white rats post-
|
MAC_Bench/ACS/Story/ACS Food Science & Technology/2024_11.txt
|
vitg
|
2024_11.txt
|
–liquid microextraction combined with the solidification of the aqueous phase. This method provides a reliable, sensitive, user-friendly, and eco-friendly alternative for detecting acrylamide levels in vegetable and fruit chips. The graphic was designed with the use of Microsoft Copilot.
|
MAC_Bench/ACS/Story/ACS Food Science & Technology/2024_5.txt
|
groundtruth
|
2024_5.txt
|
test
|
Crystal Growth & Design
|
2024_11
|
Which of the following options best describe the cover image?
|
MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_11.png
|
A
|
The convolution of spatial confinement and interparticle interactions controls the formation of superparticles differing in structure and function, resulting in emergent properties. In this review, Marino et al. discuss recent developments in this topical area spanning length scales of colloidal particle assembly from nano- to micrometers. The cover image was AI-generated using Microsoft Copilot.
|
MAC_Bench/ACS/Story/Crystal Growth & Design/2024_11.txt
|
groundtruth
|
2024_11.txt
|
Twenty years and 19 volumes of Crystal Growth & Design represented by our first cover and the CGD fashion statements over the years.
|
MAC_Bench/ACS/Story/Crystal Growth & Design/2019_1.txt
|
vitg
|
2019_1.txt
|
supramolecular polymeric motifs are combined in one crystal to produce the platforms for multimodal thermally tuned blue-to-green and/or NIR photoluminescence. The background of the cover image was generated by artificial intelligence (AI) using Microsoft Copilot.
|
MAC_Bench/ACS/Story/Crystal Growth & Design/2024_4.txt
|
vith
|
2024_4.txt
|
The cover shows two conformers of resorcinol and a single crystal of resorcinol polymorphs α grown in a high-pressure diamond-anvil cell. Resorcinol polymorphs were determined in the 1930s, but their metastable phases, symmetry, and densities have remained puzzling. The high-pressure structures reveal the mechanism destabilizing polymorphs α and β, involving the molecular conformation and directions of hydrogen bonds
|
MAC_Bench/ACS/Story/Crystal Growth & Design/2019_3.txt
|
clip
|
2019_3.txt
|
test
|
Lab Animal
|
53_5
|
Which of the following options best describe the cover image?
|
MAC_Bench/Nature/Cover/Lab Animal/53_5.png
|
C
|
Meet the mimics
Ethology has a new tool. Robots are becoming an important part of study with several different groups from around the world constructing models of everything from insects to mammals in the hopes of understanding and ultimately modifying animal behavior.
See Katsnelson
Image: higyou / iStock / Getty Images Plus. Cover design: Erin Dewalt
|
MAC_Bench/Nature/Story/Lab Animal/47_4.txt
|
clip
|
47_4.txt
|
Refining the housing and husbandry of laboratory rats
Housing and husbandry conditions are known to affect animal welfare and research outcomes. In a new article, Neville et al. conducted a mapping review of refinements to laboratory rat housing and husbandry, and identified specific interventions that are likely to generate welfare improvements.
See Neville et al.
COVER IMAGE: Marina Spence. COVER DESIGN: Marina Spence.
|
MAC_Bench/Nature/Story/Lab Animal/52_10.txt
|
vitg
|
52_10.txt
|
New tool for monitoring mouse subretinal fibrosis
Efficient tools for monitoring fibrosis-related changes in neovascular age-related macular degeneration are lacking. Linder et al. describe the first use of fluorescently labeled collagen hybridizing peptides to directly image collagen remodeling and monitor fibrosis in two mouse models of ocular neovascularization.
See Linder
Cover image: Zentangle / iStock / Getty Images Plus and Marina Spence. Cover design: Marina Spence.
|
MAC_Bench/Nature/Story/Lab Animal/53_5.txt
|
groundtruth
|
53_5.txt
|
Licensing out that novel mouse
A novel mouse model can be a valuable asset to the institution that developed it. Understanding the various distribution agreements available can help developers protect their intellectual property (IP) while still getting their new mouse out to others to use. That’s more important than ever as technological advances in making new models change the IP landscape.
See Weintraub
Cover design: Erin Dewalt
|
MAC_Bench/Nature/Story/Lab Animal/48_7.txt
|
vith
|
48_7.txt
|
train
|
Cell Stem Cell
|
31_8
|
Which of the following options best describe the cover image?
|
MAC_Bench/Cell/Cover/Cell Stem Cell/31_8.png
|
C
|
On the cover: The cover illustrates the themes of both communication between different
stakeholders in regenerative medicine and repair processes mediated by stem cells.
Cover design by Yvonne Blanco.
|
MAC_Bench/Cell/Story/Cell Stem Cell/8_1.txt
|
clip
|
8_1.txt
|
On the cover: This month's cover presents an artistic interpretation of the passage
of time for stem cells to complement our special review issue on Stem Cells in Aging.
Image created by Yvonne Blanco.
|
MAC_Bench/Cell/Story/Cell Stem Cell/16_1.txt
|
ave_2
|
16_1.txt
|
On the cover: In this issue, Sun et al. report that the neonatal spinal cord extracellular matrix (ECM) provides developmental
cues for spinal cord neural progenitor cells and organoids to promote host-graft neural
connections, thereby enhancing the therapeutic effects on spinal cord injury. Their
findings suggest that the remarkable regenerative ability of the neonatal spinal cord
may stem from its favorable ECM environment. The cover shows the neonatal spinal cord
ECM molecular “workers” connecting the axonal “cables” of the organoid spheroids to
spinal cord “plugs” to rebuild the neural network. Image courtesy of the authors.
|
MAC_Bench/Cell/Story/Cell Stem Cell/31_8.txt
|
groundtruth
|
31_8.txt
|
On the cover: In two reports appearing in Cell Stem Cell and Cell Reports Medicine, Ramzy et al. (https://doi.org/10.1016/j.stem.2021.10.003) and Shapiro et al. (https://doi.org/10.1016/j.xcrm.2021.100466) provide evidence that stem cell-derived pancreatic endoderm cells can mature into
glucose-responsive, insulin-producing β cells in patients with type 1 diabetes. The
cover art depicts a small sapling representing the nascent therapy of treating diabetes
with stem cell-derived cells “encapsulated” within the leaves. The success of this
research draws upon a century of fundamental research shown in the roots, including
the discovery of insulin, cadaveric islet transplantation, pancreatic islet biology,
the discovery of embryonic stem cells within blastocysts, and the development of in vitro differentiation protocols. Image courtesy of Ramzy and Kieffer.
|
MAC_Bench/Cell/Story/Cell Stem Cell/28_1.txt
|
vitg
|
28_1.txt
|
train
|
Nature Food
|
5_10
|
Which of the following options best describe the cover image?
|
MAC_Bench/Nature/Cover/Nature Food/5_10.png
|
D
|
Marine resources for aquaculture
Salmon aquaculture is projected to grow by 2–3% per year to meet the increasing demand for aquatic foods. Wild-caught, marine-derived resources in the form of fish meal and fish oil are key sources of protein and lipids in salmon aquafeed formulations, but with wild fish stocks stagnating, this resource presents a limiting factor for future sector growth. Global salmon production potential was modelled, incorporating a 1–3% growth rate and exploring a variety of fish oil and fish meal utilization scenarios. Incorporating 3% fish oil and 3% fish meal in aquafeed could permit 2% per year production growth until 2100 — independent of novel aquaculture feeds that are currently being utilized.
Aquatic foods, such as salmon, form an important dietary source of long-chain omega-3 fatty acids. Based on these findings, 300 grams of salmon per week would provide almost all the recommended weekly intake of eicosapentaenoic acid and docosahexaenoic acid — demonstrating that finite marine resources, when used judiciously, can contribute to salmon aquaculture sector growth and healthy diets.
See Rocker et al.
Image: Marc Guitard/Moment/Getty. Cover Design: Tulsi Voralia.
|
MAC_Bench/Nature/Story/Nature Food/3_5.txt
|
ave_1
|
3_5.txt
|
One Health aquaculture
Aquaculture, the farming of aquatic animals and plants, is one of the fastest developing food sectors globally, and in recent years has become the main source of fish available for human consumption. Applying the principles of One Health — the interconnectedness of human, animal and planetary health — could well support enhanced sustainable production in aquaculture; facilitating food and nutrition security, poverty alleviation, economic development and the protection of natural resources.
See Stentiford et al.
Image: Sami Sarkis/Photographer's Choice RF/Getty. Cover Design: Tulsi Voralia
|
MAC_Bench/Nature/Story/Nature Food/1_5.txt
|
ave_3
|
1_5.txt
|
Nature Food
Since the publication of Nature Food’s first issue in January 2020, food systems research has come a long way — and much remains to be done. We celebrate the journal’s anniversary with a Focus issue and a webinar series.
See Editorial
Image: Shawn Williams / Alamy Stock Photo. Cover design: Tulsi Voralia
|
MAC_Bench/Nature/Story/Nature Food/6_1.txt
|
clip
|
6_1.txt
|
Nutrient retention in aquaculture
Salmon has one of the most efficient feed-to-food conversion rates among farmed animals, but its high trophic level makes salmon aquaculture a major consumer of marine resources — including species that are consumed directly by people, such as herring and mackerel. Re-allocating species currently used in salmon feeds towards direct human consumption can increase the overall amount of nutritious seafood while avoiding increases in wild-caught fish supply. Most edible feed fish contains higher concentrations of omega-3 fatty acids, iodine, calcium, iron and vitamin A than farmed salmon. Nutrient retention approaches can drive better performance of aquaculture and identify pathways towards sustainable growth.
See Willer et al.
Image: Jeff Rotman / Alamy Stock Photo. Cover Design: Tulsi Voralia.
|
MAC_Bench/Nature/Story/Nature Food/5_10.txt
|
groundtruth
|
5_10.txt
|
train
|
Trends in Microbiology
|
32_8
|
Which of the following options best describe the cover image?
|
MAC_Bench/Cell/Cover/Trends in Microbiology/32_8.png
|
B
|
This themed issue of Trends in Microbiology examines the role that metabolism plays
in microbial life ranging from how microbes obtain energy to how microbes can alter
the metabolism of their host and use host-derived metabolites to their advantage.
The cover image was inspired by the hypothesis that perhaps pathogenic bacteria might
just be looking for food, which is discussed by Rohmer et al. on pages 341–348. Cover
image courtesy Rodolphe ‘Rodho’ Grandviennot.
|
MAC_Bench/Cell/Story/Trends in Microbiology/19_6.txt
|
vitg
|
19_6.txt
|
Nitrogen (N) is absolutely essential to life as we know it. Though
atmospherically abundant, N must first be converted, or “fixed,” prior to biological
uptake
and crop fertilizer manufacturing. Synthetic N-fixation, today responsible for half
of all fixed
N, comes with profound economic and environmental costs. Fortunately, an alternative,
ancient biological strategy—catalyzed by microbially hosted nitrogenase proteins—holds
enormous bioengineering potential for sustainable N-fixation. Yet, researchers have
been
unable to mimic this elegant biological solution and lack an understanding of environmental
drivers in its evolution, limiting predictions for how biological N-fixation will
respond to a
changing climate. In this special issue, Holly Rucker and Betül Kaçar review the complex
history of nitrogen fixation over billions of years of planetary history.
Image courtesy: Prof. Betül Kaçar, UW-Madison.
|
MAC_Bench/Cell/Story/Trends in Microbiology/32_8.txt
|
groundtruth
|
32_8.txt
|
This themed issue of Trends in Microbiology examines some of the ways that a systems
biology approach has been used in microbiological research. As this often involves
the manipulation of large data sets that can include networks of genes, genomes or
protein interactions, for example, this cover playfully shows another type of network,
that of an imagined tree-like subway system. Cover image printed with permission from
Robert Adrian Hillman/iStockphoto LP.
|
MAC_Bench/Cell/Story/Trends in Microbiology/19_3.txt
|
vith
|
19_3.txt
|
This themed issue of Trends in Microbiology explores different aspects of microbial endurance and how microbes endure and flourish
in the environments they find themselves in. We examine how bacteria and viruses establish
chronic infections – from adaptation and population diversity, to the latent reservoir
in HIV as well as how this might be eliminated, and reactivation of latency. We discuss
how bacteria respond to stressful conditions from responses from the immune system
to antimicrobials and how the stress response is regulated. We also look at endurance
in beneficial interactions and how a stable gut microbiota is maintained and how stress
can act as a cue in symbiosis. Finally, we explore what endurance might mean for the
field of microbiology and how this might evolve in the 21st Century. The cover image by Kip Lyall playfully imagines what microbial endurance
might look like if microbes ran in marathons.
|
MAC_Bench/Cell/Story/Trends in Microbiology/24_9.txt
|
clip
|
24_9.txt
|
train
|
Nature Aging
|
5_1
|
Which of the following options best describe the cover image?
|
MAC_Bench/Nature/Cover/Nature Aging/5_1.png
|
D
|
Aging in unity
The cover image of Nature Aging’s first issue illustrates the notion that aging concerns everyone, pointing to the need for social unity and joined research endeavors to solve issues and seize opportunities associated with human aging. Our first issue features research and opinion articles authored by biologists, clinicians, social scientists and civil society and industry leaders that reflect the breadth of our interests, from the intricate details of the core biology of aging to public health and societal questions associated with population aging.
See Editorial
Image: Smartboy10 / DigitalVisionVectors / Getty. Cover design: Lauren Heslop.
|
MAC_Bench/Nature/Story/Nature Aging/1_12.txt
|
clip
|
1_12.txt
|
Focus on reproductive aging
Reproductive aging is an important determinant of fertility span and overall health and wellbeing in older age. In this issue, Nature Aging presents a series of reviews and opinion pieces on recent advances and future directions in reproductive aging research. The cover image shows seasonally colored trees — a springtime tree in green, and autumn trees in brilliant yellow and red — that represent different stages of reproductive physiology in aging.
See Editorial
Image: Alex Whitworth. Cover design: Alex Whitworth
|
MAC_Bench/Nature/Story/Nature Aging/4_1.txt
|
vitg
|
4_1.txt
|
Single-cell epigenetic age estimation
In this issue, a study by Trapp et al. introduces scAge, a computational framework that enables epigenetic age estimation at single-cell resolution. The new method can track the aging process in individual cells and its heterogeneity in tissue. Notably, scAge revealed a natural cellular rejuvenation event occurring during early embryogenesis. The issue cover features a cell, whose genome blends into the outline of a clock — its hands, denoting age, are driven by the CpG methylation patterns on the DNA.
See Trapp et al. and the accompanying News & Views by K. Lenhard Rudolph
Cover image: Tiamat Fox. Cover Design: Lauren Heslop
|
MAC_Bench/Nature/Story/Nature Aging/1_1.txt
|
vith
|
1_1.txt
|
Immune clearance of senescent cells
In this issue, Xinliang Ming, Ze Yang, Yuqiao Huang and colleagues develop a bifunctional peptide that links senescent and natural killer cells to induce immunological removal of senescent cells in fibrosis, injury, cancer and naturally aged mouse models. The cover image depicts the peptide as a scale on which senescent cells (left) are balanced with immune cells (right). The beneficial effects of this immunotherapy approach are symbolized by scattering senescent cells and sprouting tree branches.
See Ming et al.
Image: Ben Wang, Zhejiang University. Cover design: Lauren Heslop
|
MAC_Bench/Nature/Story/Nature Aging/5_1.txt
|
groundtruth
|
5_1.txt
|
test
|
iScience
|
27_3
|
Which of the following options best describe the cover image?
|
MAC_Bench/Cell/Cover/iScience/27_3.png
|
B
|
On the cover: Movable scattered units engraved with different types of cells gradually
assemble into a human shape. The accumulation of single-cell data provides growing
resources for constructing atlases for all cells of a human organ or the whole body.
Chen et al. (2022) developed a unified informatics framework that enables seamless
cell-centric assembly of scRNA-seq data from diverse sources and built the first human
ensemble cell atlas (hECA). hECA enables “in-data” exploration of the atlas as a virtual
human body with customizable logic expressions on all recorded features of the assembled
cells, provides quantitative portraitures of biological entities (organs, cell types,
and genes), and facilitates cell-type annotations with customizable references. Artwork
by Yuankui Lyu and Ruoqi Li, created with BioRender.com.
|
MAC_Bench/Cell/Story/iScience/25_7.txt
|
clip
|
25_7.txt
|
The cover image is a digital artwork visualizing whale songs recorded by an ocean-bottom
seismometer array. Utilizing spectrum analysis and dynamic imaging techniques, Ren et al. created visuals based on the variation in the amplitudes of the seismic waveforms.
The higher amplitude indicates that the recorded noise was closer to the seismometer,
and the greater energy level of the whale song resulted in a more accurate silhouette
of the whale. The authors further integrated artistic methodologies to produce images
and videos from seismic waveforms recorded in the ocean, which enable the general
public to gain a multisensory experience of the ocean soundscape studied by specialists.
Their artwork provides new dimensions of scientific data representation, while its
creation is also driven by the analysis of scientific datasets.
|
MAC_Bench/Cell/Story/iScience/27_3.txt
|
groundtruth
|
27_3.txt
|
On the cover: Plant responses to flooding are regulated through partially similar
regulators as responses to shade. This cover depicts an infrared image of a waterlogged
tomato plant illuminated with far-red light at the base of the stem. See Courbier
et al., vol. 22, 2019.
|
MAC_Bench/Cell/Story/iScience/23_12.txt
|
vith
|
23_12.txt
|
On the cover: In this issue of iScience, Enoki et al. performed time-lapse imaging of the circadian rhythm in mammalian master clock neurons
under warm and cold temperatures and asked whether the circadian clock continues or
stops during hypothermia. In the image, the animals are seated around the table at
Alice's “A Mad Tea Party” and are served either cold or hot tea, and the animals have
their own clocks. During the cold winter season (far side), the animals hibernate
with a stopped clock controlled by a hatmaker of calcium ions. In the warm spring
(rear side), the animals wake up, and the clock starts ticking again at the same time
as the environmental clock. Cover artwork by Keiko Nakamura (Space-Time Inc.) and
Hiroyuki Adachi (Sofa Graphic Design).
|
MAC_Bench/Cell/Story/iScience/26_1.txt
|
vitg
|
26_1.txt
|
val
|
ACS Infectious Diseases
|
2024_10
|
Which of the following options best describe the cover image?
|
MAC_Bench/ACS/Cover/ACS Infectious Diseases/2024_10.png
|
D
|
This cover shows a novel antiplasmodial agent attacking Plasmodium falciparum parasites in infected red blood cells. This new compound was re-engineered from the indole alkaloid yohimbine using a “ring distortion” chemical synthesis approach reported by Huigens, Chakrabarti, and co-workers. Artwork created by
|
MAC_Bench/ACS/Story/ACS Infectious Diseases/2020_11.txt
|
vitg
|
2020_11.txt
|
The cover art depicts how the tricyclic β-lactam attacks carbapenem-resistant Enterobacterales by overcoming three resistance mechanisms, which are β-lactamase production, porin deficiency, and the insertion mutation of four amino acids into penicillin-binding protein 3.
|
MAC_Bench/ACS/Story/ACS Infectious Diseases/2022_10.txt
|
clip
|
2022_10.txt
|
The cover depicts a microbiome wherein E. coli (blue) responds to quorum sensing signaling molecules produced by other bacteria. This issue features an article by Styles et al. who report new chemical modulators of an E. coli quorum sensing receptor and the characterization of the mode-of-action of a covalent inhibitor using top-down mass spectrometry.
|
MAC_Bench/ACS/Story/ACS Infectious Diseases/2020_1.txt
|
ave_2
|
2020_1.txt
|
Bi(III)-based compounds can allosterically target a SARS-CoV-2 nsp14/nsp10 complex to disrupt its MTase and ExoN activity, leading to inhibition of SARS-CoV-2 replication in mammalian cells, which is attributable to the Bi compounds’ ability to displace zinc ions from the zinc-finger sites of the nsp14/nsp10 complex and
|
MAC_Bench/ACS/Story/ACS Infectious Diseases/2024_10.txt
|
groundtruth
|
2024_10.txt
|
train
|
Science Advances
|
11_7
|
Which of the following options best describe the cover image?
|
MAC_Bench/Science/Cover/Science Advances/11_7.png
|
C
|
ONLINE COVER A frontlit lithophane graphic of the reaction for isoamyl acetate. To increase the access to high-resolution data for people with blindness, lithophane graphics were developed using 3D-printing. Alonzo et al. report the creation of lithophane codices with greater resolution and an unlimited range of protuberance compared to existing swell form graphics. High school students with blindness were able to accurately interpret lithophanes of esterification reactions, despite little or no prior training in chemistry or experience with lithophanes, resulting in an increased student interest and sense of belonging in science. Credit: Mayte Gonzalez
|
MAC_Bench/Science/Story/Science Advances/10_2.txt
|
vitg
|
10_2.txt
|
ONLINE COVER Mushroom growing from tree in a moist Pacific Northwest forest. One way vascular plants obtain soil nutrients is through mycorrhizal symbiosis, a strategy that can expand root surface area to increase absorption. Deng et al. offer evidence that types of mycorrhizae mediate plant interactions and the biodiversity -productivity relationship in diverse forests. The results suggest that mycorrhizal responses to climate change factors should be considered in forest management, particularly in the selection of tree species for both timber production and climate change mitigation. Credit: RobH/Getty Images
|
MAC_Bench/Science/Story/Science Advances/9_3.txt
|
vith
|
9_3.txt
|
ONLINE COVER Habitat and structural home of the fungus-cyanobacterium complex S. cyanobacteriicola-S. taiwanensis. Fungi often form the outer structure in symbiotic relationships such as lichens. However, Chen et al. discovered a symbiosis in Taiwan’s subtropical forests where fungi live within cyanobacterial sheaths, forming erect, nitrogen-fixing thalli. The discovery of the fungus-cyanobacterium complex demonstrates unique fungi residing within structures built by cyanobacteria. This finding sheds light on unique forms of symbiosis and expands our understanding of fungal partnerships in nature. Credit: Che-Chih Chen
|
MAC_Bench/Science/Story/Science Advances/11_7.txt
|
groundtruth
|
11_7.txt
|
ONLINE COVER Tears reveal more than just emotion. Tears' extracellular vesicles (EVs) allow us to see molecular-level signs of different diseases or actions of other organs inside our bodies. Hu et al. found that tear EVs act as immune effectors, maintain retinal homeostasis, and regulate inflammation. The rich bioinformation that tears carry offer value beyond the ocular system. Credit: Hu et alMAC_Bench/Science Advances
|
MAC_Bench/Science/Story/Science Advances/9_11.txt
|
clip
|
9_11.txt
|
test
|
Nature Chemical Engineering
|
1_12
|
Which of the following options best describe the cover image?
|
MAC_Bench/Nature/Cover/Nature Chemical Engineering/1_12.png
|
C
|
Stirring up plastics recycling
Emerging catalytic techniques can valorize plastic waste into valuable products. In addition to the ongoing search for more effective catalysts, disclosing the potential of these technologies requires dedicated reaction engineering efforts. Now, Javier Pérez-Ramírez and co-workers show how critical optimal mixing is in the three-phase hydrogenolysis of polyolefins. Following catalytic evaluation and computational fluid dynamics simulations, they derive an accessible quantitative criterion for determining stirring configurations to maximize catalyst effectiveness. This marks an important step towards standardized benchmarking of catalytic technologies. The cover depicts the top view of catalyst particle trajectories in a plastic melt when stirred with the optimal geometry.
See Jaydev et al. and Soltani & Rorrer
Image: Constance Ko and Javier Pérez-Ramírez, ETH Zurich. Cover design: Thomas Phillips.
|
MAC_Bench/Nature/Story/Nature Chemical Engineering/1_4.txt
|
ave_1
|
1_4.txt
|
Electrified processing of carbonates to ethylene
Industrial processes for the electrochemical production of ethylene from aqueous carbonate feedstocks are not well understood. Now, Sankar Nair and co-workers report process simulations and a techno-economic analysis to identify barriers to the future commercialization of this technology as well as advances needed to make the process feasible. The image illustrates an industrial-scale process designed to produce ethylene from carbon dioxide captured from the air through electrochemical reduction. It shows the flow of various species between the units in the process. It also highlights the complexities involved in optimizing the economics and evaluating the uncertainties of the process using computational approaches.
See Venkataraman et al.
Image: Anush Venkataraman, Georgia Institute of Technology. Cover design: Laoise Mac Gabhann.
|
MAC_Bench/Nature/Story/Nature Chemical Engineering/1_2.txt
|
vitg
|
1_2.txt
|
Lignin refined
Recalcitrant C–C bonds in lignin limit the monomer yield of current depolymerization strategies that target labile C–O bonds. Now, Emiel Hensen and colleagues present a process based on a bifunctional Pt/zeolite catalyst that selectively cleaves common C–C linkages in lignins, resulting in substantially increased fuel yields from common lignin sources.
See Luo et al. and Subbotina & Samec
Image: Hassan Tahini, ScienceBrush Design. Cover Design: Thomas Phillips.
|
MAC_Bench/Nature/Story/Nature Chemical Engineering/1_12.txt
|
groundtruth
|
1_12.txt
|
Microbial fragrance production
Benzyl acetate, a compound with a jasmine-like scent used in various products, is traditionally made through inefficient plant extraction or chemical methods. Now, Choi, Lee and colleagues have developed a more sustainable method using a metabolically engineered bacterium to produce benzyl acetate, achieving significant production levels in a fermentation process. The cover shows a 300-liter pilot-scale fermentor at KAIST, Korea.
See Choi et al. and Sokolova & Haslinger
Image: Kyeong Rok Choi and Sang Yup Lee, Korea Advanced Institute of Science & Technology. Cover Design: Thomas Phillips.
|
MAC_Bench/Nature/Story/Nature Chemical Engineering/1_10.txt
|
clip
|
1_10.txt
|
train
|
Joule
|
8_11
|
Which of the following options best describe the cover image?
|
MAC_Bench/Cell/Cover/Joule/8_11.png
|
C
|
On the Cover: The image presents the Science Tower in Graz, Austria, whose top features
1,000 m2 semitransparent dye-sensitized glass panels converting solar energy into electrical
energy. In this issue of Joule, Wang et al. (pp. 2065–2075) demonstrate the combination
of two judiciously designed organic dyes with a cheap ionic liquid electrolyte offering
both high efficiency and outstanding stability. Their findings will greatly benefit
this aesthetically attractive photovoltaic technology, whose deployment will contribute
to the future supply of renewable energy. Photograph courtesy of H. Glass.
|
MAC_Bench/Cell/Story/Joule/2_3.txt
|
ave_1
|
2_3.txt
|
On the cover: Joule is the home for scale-spanning energy research that plays a key role in the transition
to a cleaner, more sustainable future. This issue features a range of articles that
reflect themes relevant to COP26, covering fundamental research, technoeconomics,
and policy analysis that will enable the realization of net zero this century and
help to mitigate the climate crisis. Cover art by Phillip Krzeminski.
|
MAC_Bench/Cell/Story/Joule/5_3.txt
|
clip
|
5_3.txt
|
On the cover: Zhang et al. develop a universal encapsulation method for commercialized perovskite solar cell
(PSC). The encapsulated PSC modules passed outdoor stability, UV preconditioning,
and hail tests according to the International Electrotechnical Commission 61215 standard.
Image credit: Guodong Zhang, Yifan Zheng, and Yuchuan Shao.
|
MAC_Bench/Cell/Story/Joule/8_11.txt
|
groundtruth
|
8_11.txt
|
On the Cover: The cover image represents putting the “pieces” together of renewable
building blocks from biomass with reclaimed PET (rPET) to synthesize fiberglass-reinforced
plastics (FRPs) that can be used in high-value materials applications such as in wind
turbine blades. In this issue of Joule, Rorrer et al. (1006–1027) demonstrate that rPET can be deconstructed and subsequently
combined with monomers obtainable from biomass. The resulting FRPs exhibit superior
mechanical properties compared to the petroleum-based incumbent while using significantly
less energy in their manufacture on a per dollar basis when compared to typical-FRP
manufacture and chemical bottle-to-bottle recycling. Cover art by Ella Maru Studio.
|
MAC_Bench/Cell/Story/Joule/3_9.txt
|
ave_2
|
3_9.txt
|
val
|
NATURE GENETICS
|
56_9
|
Which of the following options best describe the cover image?
|
MAC_Bench/Nature/Cover/NATURE GENETICS/56_9.png
|
D
|
Mendel and memories
In celebration of the 200th anniversary of Gregor Mendel’s birth and the 30th anniversary of the launch of Nature Genetics, we look both forwards and backwards at how far the genetics field has come. This cover image is inspired by the cover of the first issue of Nature Genetics in 1992.
Image and Cover Design: Valentina Monaco.
|
MAC_Bench/Nature/Story/NATURE GENETICS/54_6.txt
|
vitg
|
54_6.txt
|
Peanut global phenotypic variation
Chloroplast and whole-genome sequencing of Arachis accessions sheds light on peanut evolutionary history and phenotypic diversification.
See Zheng et al.
Image: Nastasic/DigitalVision Vectors/Getty. Cover design: Laoise Mac Gabhann.
|
MAC_Bench/Nature/Story/NATURE GENETICS/56_4.txt
|
clip
|
56_4.txt
|
Lychee fruit genome
Sequencing of the genome of the lychee cultivar ‘Feizixiao’, along with analysis of 72 re-sequenced lychee accessions, identifies two different domestication events: one in Yunnan, and one in Hainan.
See Hu et al.
Image: Inge Johnsson / Alamy Stock Photo. Cover Design: Valentina Monaco.
|
MAC_Bench/Nature/Story/NATURE GENETICS/54_12.txt
|
vith
|
54_12.txt
|
Coffea arabica diversification history
Genome assemblies of allotetraploid Coffea arabica and representatives of its diploid progenitors provide insights into diversification history.
See Salojärvi et al.
Image: Amanda van der Sijs/500px/Getty. Cover design: Tulsi Voralia
|
MAC_Bench/Nature/Story/NATURE GENETICS/56_9.txt
|
groundtruth
|
56_9.txt
|
test
|
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